Amino acid dipepetide frequency for Heterobasidion partitivirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.072AlaAla: 5.072 ± 2.729
0.725AlaCys: 0.725 ± 0.536
3.623AlaAsp: 3.623 ± 0.63
1.449AlaGlu: 1.449 ± 0.047
4.348AlaPhe: 4.348 ± 2.938
2.174AlaGly: 2.174 ± 0.443
2.899AlaHis: 2.899 ± 0.094
3.623AlaIle: 3.623 ± 0.396
2.899AlaLys: 2.899 ± 0.094
2.174AlaLeu: 2.174 ± 0.443
1.449AlaMet: 1.449 ± 0.979
4.348AlaAsn: 4.348 ± 0.141
6.522AlaPro: 6.522 ± 1.75
2.899AlaGln: 2.899 ± 0.094
4.348AlaArg: 4.348 ± 2.193
5.072AlaSer: 5.072 ± 2.729
7.246AlaThr: 7.246 ± 2.286
4.348AlaVal: 4.348 ± 2.193
0.725AlaTrp: 0.725 ± 0.536
4.348AlaTyr: 4.348 ± 0.141
0.0AlaXaa: 0.0 ± 0.0
Cys
2.174CysAla: 2.174 ± 0.583
0.0CysCys: 0.0 ± 0.0
0.725CysAsp: 0.725 ± 0.49
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.174CysLeu: 2.174 ± 0.443
0.0CysMet: 0.0 ± 0.0
0.725CysAsn: 0.725 ± 0.49
0.725CysPro: 0.725 ± 0.49
1.449CysGln: 1.449 ± 0.979
1.449CysArg: 1.449 ± 0.979
0.725CysSer: 0.725 ± 0.536
1.449CysThr: 1.449 ± 0.047
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.623AspAla: 3.623 ± 0.63
1.449AspCys: 1.449 ± 0.047
5.072AspAsp: 5.072 ± 1.375
2.899AspGlu: 2.899 ± 0.094
2.174AspPhe: 2.174 ± 0.583
2.899AspGly: 2.899 ± 0.094
0.0AspHis: 0.0 ± 0.0
2.174AspIle: 2.174 ± 0.443
2.174AspLys: 2.174 ± 0.443
7.971AspLeu: 7.971 ± 0.771
0.725AspMet: 0.725 ± 0.536
1.449AspAsn: 1.449 ± 0.979
3.623AspPro: 3.623 ± 1.656
3.623AspGln: 3.623 ± 1.422
3.623AspArg: 3.623 ± 1.422
6.522AspSer: 6.522 ± 0.302
2.174AspThr: 2.174 ± 0.443
5.072AspVal: 5.072 ± 0.677
0.725AspTrp: 0.725 ± 0.49
3.623AspTyr: 3.623 ± 1.422
0.0AspXaa: 0.0 ± 0.0
Glu
1.449GluAla: 1.449 ± 0.047
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
0.725GluGlu: 0.725 ± 0.49
2.174GluPhe: 2.174 ± 0.443
0.0GluGly: 0.0 ± 0.0
1.449GluHis: 1.449 ± 0.979
2.899GluIle: 2.899 ± 1.12
0.725GluLys: 0.725 ± 0.49
4.348GluLeu: 4.348 ± 0.141
0.725GluMet: 0.725 ± 0.536
1.449GluAsn: 1.449 ± 0.047
0.0GluPro: 0.0 ± 0.0
2.174GluGln: 2.174 ± 0.443
1.449GluArg: 1.449 ± 0.047
2.899GluSer: 2.899 ± 0.094
1.449GluThr: 1.449 ± 0.047
4.348GluVal: 4.348 ± 0.886
0.725GluTrp: 0.725 ± 0.49
2.899GluTyr: 2.899 ± 1.959
0.0GluXaa: 0.0 ± 0.0
Phe
4.348PheAla: 4.348 ± 0.886
2.174PheCys: 2.174 ± 0.443
3.623PheAsp: 3.623 ± 0.396
2.899PheGlu: 2.899 ± 0.094
3.623PhePhe: 3.623 ± 0.63
5.072PheGly: 5.072 ± 1.703
2.174PheHis: 2.174 ± 1.469
5.797PheIle: 5.797 ± 2.891
0.725PheLys: 0.725 ± 0.49
6.522PheLeu: 6.522 ± 0.724
2.899PheMet: 2.899 ± 1.733
4.348PheAsn: 4.348 ± 1.912
2.174PhePro: 2.174 ± 0.443
0.725PheGln: 0.725 ± 0.49
2.174PheArg: 2.174 ± 0.583
5.797PheSer: 5.797 ± 2.24
4.348PheThr: 4.348 ± 0.141
5.072PheVal: 5.072 ± 2.729
1.449PheTrp: 1.449 ± 0.979
3.623PheTyr: 3.623 ± 1.422
0.0PheXaa: 0.0 ± 0.0
Gly
0.725GlyAla: 0.725 ± 0.536
0.725GlyCys: 0.725 ± 0.536
3.623GlyAsp: 3.623 ± 0.63
1.449GlyGlu: 1.449 ± 1.073
6.522GlyPhe: 6.522 ± 2.354
2.174GlyGly: 2.174 ± 0.443
2.174GlyHis: 2.174 ± 0.583
5.072GlyIle: 5.072 ± 0.677
0.725GlyLys: 0.725 ± 0.536
3.623GlyLeu: 3.623 ± 0.63
1.449GlyMet: 1.449 ± 0.979
2.174GlyAsn: 2.174 ± 1.609
0.725GlyPro: 0.725 ± 0.49
0.0GlyGln: 0.0 ± 0.0
2.899GlyArg: 2.899 ± 2.146
3.623GlySer: 3.623 ± 1.656
1.449GlyThr: 1.449 ± 1.073
0.725GlyVal: 0.725 ± 0.49
0.0GlyTrp: 0.0 ± 0.0
3.623GlyTyr: 3.623 ± 2.448
0.0GlyXaa: 0.0 ± 0.0
His
4.348HisAla: 4.348 ± 0.141
0.725HisCys: 0.725 ± 0.49
2.174HisAsp: 2.174 ± 1.469
0.0HisGlu: 0.0 ± 0.0
2.174HisPhe: 2.174 ± 1.469
2.899HisGly: 2.899 ± 0.094
1.449HisHis: 1.449 ± 0.979
0.725HisIle: 0.725 ± 0.49
2.899HisLys: 2.899 ± 0.094
2.174HisLeu: 2.174 ± 0.443
2.174HisMet: 2.174 ± 0.583
3.623HisAsn: 3.623 ± 0.63
2.174HisPro: 2.174 ± 1.609
0.0HisGln: 0.0 ± 0.0
2.174HisArg: 2.174 ± 0.443
2.899HisSer: 2.899 ± 0.094
2.899HisThr: 2.899 ± 0.094
0.725HisVal: 0.725 ± 0.49
0.725HisTrp: 0.725 ± 0.49
1.449HisTyr: 1.449 ± 0.047
0.0HisXaa: 0.0 ± 0.0
Ile
5.072IleAla: 5.072 ± 0.677
0.725IleCys: 0.725 ± 0.49
3.623IleAsp: 3.623 ± 0.63
3.623IleGlu: 3.623 ± 1.422
7.246IlePhe: 7.246 ± 0.792
2.899IleGly: 2.899 ± 1.12
0.725IleHis: 0.725 ± 0.49
2.174IleIle: 2.174 ± 0.443
4.348IleLys: 4.348 ± 1.912
5.072IleLeu: 5.072 ± 0.349
2.174IleMet: 2.174 ± 0.443
2.174IleAsn: 2.174 ± 1.609
2.899IlePro: 2.899 ± 1.12
2.899IleGln: 2.899 ± 0.094
3.623IleArg: 3.623 ± 0.396
2.899IleSer: 2.899 ± 0.932
2.174IleThr: 2.174 ± 0.583
2.899IleVal: 2.899 ± 0.932
0.725IleTrp: 0.725 ± 0.49
0.725IleTyr: 0.725 ± 0.49
0.0IleXaa: 0.0 ± 0.0
Lys
1.449LysAla: 1.449 ± 1.073
0.0LysCys: 0.0 ± 0.0
2.174LysAsp: 2.174 ± 1.469
0.725LysGlu: 0.725 ± 0.49
0.725LysPhe: 0.725 ± 0.536
2.174LysGly: 2.174 ± 0.583
2.899LysHis: 2.899 ± 0.932
1.449LysIle: 1.449 ± 0.979
0.0LysLys: 0.0 ± 0.0
7.246LysLeu: 7.246 ± 3.87
1.449LysMet: 1.449 ± 0.979
0.725LysAsn: 0.725 ± 0.49
0.725LysPro: 0.725 ± 0.49
1.449LysGln: 1.449 ± 1.073
0.725LysArg: 0.725 ± 0.49
2.899LysSer: 2.899 ± 0.932
1.449LysThr: 1.449 ± 0.979
2.899LysVal: 2.899 ± 1.12
0.725LysTrp: 0.725 ± 0.49
2.899LysTyr: 2.899 ± 0.932
0.0LysXaa: 0.0 ± 0.0
Leu
5.072LeuAla: 5.072 ± 1.375
1.449LeuCys: 1.449 ± 0.047
2.174LeuAsp: 2.174 ± 0.443
2.899LeuGlu: 2.899 ± 0.094
5.072LeuPhe: 5.072 ± 1.703
5.797LeuGly: 5.797 ± 0.839
2.174LeuHis: 2.174 ± 1.609
12.319LeuIle: 12.319 ± 0.911
5.072LeuLys: 5.072 ± 0.349
10.87LeuLeu: 10.87 ± 2.214
2.899LeuMet: 2.899 ± 0.094
2.174LeuAsn: 2.174 ± 0.443
9.42LeuPro: 9.42 ± 1.235
2.899LeuGln: 2.899 ± 0.932
5.797LeuArg: 5.797 ± 0.187
6.522LeuSer: 6.522 ± 1.328
5.072LeuThr: 5.072 ± 1.375
1.449LeuVal: 1.449 ± 0.047
2.899LeuTrp: 2.899 ± 0.094
2.899LeuTyr: 2.899 ± 1.12
0.0LeuXaa: 0.0 ± 0.0
Met
1.449MetAla: 1.449 ± 0.047
0.0MetCys: 0.0 ± 0.0
0.725MetAsp: 0.725 ± 0.536
0.0MetGlu: 0.0 ± 0.0
1.449MetPhe: 1.449 ± 0.979
0.0MetGly: 0.0 ± 0.0
1.449MetHis: 1.449 ± 1.073
2.174MetIle: 2.174 ± 0.583
1.449MetLys: 1.449 ± 0.047
1.449MetLeu: 1.449 ± 0.979
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.899MetPro: 2.899 ± 0.932
1.449MetGln: 1.449 ± 0.979
0.0MetArg: 0.0 ± 0.0
2.899MetSer: 2.899 ± 0.932
2.174MetThr: 2.174 ± 0.443
0.725MetVal: 0.725 ± 0.49
1.449MetTrp: 1.449 ± 0.979
0.725MetTyr: 0.725 ± 0.49
0.0MetXaa: 0.0 ± 0.0
Asn
7.971AsnAla: 7.971 ± 0.771
0.0AsnCys: 0.0 ± 0.0
0.725AsnAsp: 0.725 ± 0.49
0.725AsnGlu: 0.725 ± 0.536
2.899AsnPhe: 2.899 ± 0.932
1.449AsnGly: 1.449 ± 0.047
0.725AsnHis: 0.725 ± 0.536
3.623AsnIle: 3.623 ± 0.396
1.449AsnLys: 1.449 ± 0.047
4.348AsnLeu: 4.348 ± 0.141
0.0AsnMet: 0.0 ± 0.37
1.449AsnAsn: 1.449 ± 0.047
5.797AsnPro: 5.797 ± 0.839
2.174AsnGln: 2.174 ± 0.443
2.174AsnArg: 2.174 ± 0.583
2.899AsnSer: 2.899 ± 1.12
2.174AsnThr: 2.174 ± 0.583
3.623AsnVal: 3.623 ± 0.63
1.449AsnTrp: 1.449 ± 1.073
1.449AsnTyr: 1.449 ± 0.979
0.0AsnXaa: 0.0 ± 0.0
Pro
5.797ProAla: 5.797 ± 4.292
0.0ProCys: 0.0 ± 0.0
7.246ProAsp: 7.246 ± 0.234
5.072ProGlu: 5.072 ± 1.375
5.072ProPhe: 5.072 ± 1.375
2.174ProGly: 2.174 ± 0.583
2.899ProHis: 2.899 ± 1.959
1.449ProIle: 1.449 ± 0.047
0.0ProLys: 0.0 ± 0.0
2.899ProLeu: 2.899 ± 0.932
0.725ProMet: 0.725 ± 0.49
5.072ProAsn: 5.072 ± 1.703
2.899ProPro: 2.899 ± 1.12
2.899ProGln: 2.899 ± 1.12
3.623ProArg: 3.623 ± 0.63
7.246ProSer: 7.246 ± 1.26
6.522ProThr: 6.522 ± 1.75
2.174ProVal: 2.174 ± 0.443
0.0ProTrp: 0.0 ± 0.0
1.449ProTyr: 1.449 ± 1.073
0.0ProXaa: 0.0 ± 0.0
Gln
1.449GlnAla: 1.449 ± 0.047
0.725GlnCys: 0.725 ± 0.49
2.899GlnAsp: 2.899 ± 1.959
1.449GlnGlu: 1.449 ± 0.979
1.449GlnPhe: 1.449 ± 1.073
2.174GlnGly: 2.174 ± 0.583
2.899GlnHis: 2.899 ± 0.094
2.899GlnIle: 2.899 ± 0.932
3.623GlnLys: 3.623 ± 2.448
3.623GlnLeu: 3.623 ± 0.63
0.725GlnMet: 0.725 ± 0.536
1.449GlnAsn: 1.449 ± 1.073
0.725GlnPro: 0.725 ± 0.536
2.174GlnGln: 2.174 ± 0.443
2.899GlnArg: 2.899 ± 0.932
1.449GlnSer: 1.449 ± 0.047
0.0GlnThr: 0.0 ± 0.0
2.174GlnVal: 2.174 ± 0.583
0.725GlnTrp: 0.725 ± 0.536
2.174GlnTyr: 2.174 ± 0.443
0.0GlnXaa: 0.0 ± 0.0
Arg
2.899ArgAla: 2.899 ± 0.932
0.0ArgCys: 0.0 ± 0.0
4.348ArgAsp: 4.348 ± 0.141
0.725ArgGlu: 0.725 ± 0.49
5.072ArgPhe: 5.072 ± 0.677
1.449ArgGly: 1.449 ± 0.047
3.623ArgHis: 3.623 ± 0.396
2.174ArgIle: 2.174 ± 0.443
1.449ArgLys: 1.449 ± 0.979
5.072ArgLeu: 5.072 ± 1.375
0.725ArgMet: 0.725 ± 0.49
2.899ArgAsn: 2.899 ± 1.12
4.348ArgPro: 4.348 ± 0.141
2.899ArgGln: 2.899 ± 1.12
2.174ArgArg: 2.174 ± 1.609
2.899ArgSer: 2.899 ± 0.094
3.623ArgThr: 3.623 ± 1.656
3.623ArgVal: 3.623 ± 1.656
0.725ArgTrp: 0.725 ± 0.49
5.072ArgTyr: 5.072 ± 1.375
0.0ArgXaa: 0.0 ± 0.0
Ser
7.246SerAla: 7.246 ± 1.26
0.725SerCys: 0.725 ± 0.49
5.797SerAsp: 5.797 ± 2.24
1.449SerGlu: 1.449 ± 0.047
5.072SerPhe: 5.072 ± 0.677
4.348SerGly: 4.348 ± 0.886
1.449SerHis: 1.449 ± 1.073
2.174SerIle: 2.174 ± 0.443
3.623SerLys: 3.623 ± 1.422
8.696SerLeu: 8.696 ± 3.359
0.0SerMet: 0.0 ± 0.0
5.797SerAsn: 5.797 ± 1.213
4.348SerPro: 4.348 ± 1.167
2.899SerGln: 2.899 ± 1.12
5.797SerArg: 5.797 ± 0.839
5.797SerSer: 5.797 ± 1.213
5.797SerThr: 5.797 ± 2.24
3.623SerVal: 3.623 ± 0.396
0.0SerTrp: 0.0 ± 0.0
4.348SerTyr: 4.348 ± 1.167
0.0SerXaa: 0.0 ± 0.0
Thr
2.174ThrAla: 2.174 ± 0.583
0.0ThrCys: 0.0 ± 0.0
4.348ThrAsp: 4.348 ± 0.141
2.174ThrGlu: 2.174 ± 0.443
6.522ThrPhe: 6.522 ± 0.724
2.174ThrGly: 2.174 ± 1.609
1.449ThrHis: 1.449 ± 0.047
3.623ThrIle: 3.623 ± 0.63
0.725ThrLys: 0.725 ± 0.49
6.522ThrLeu: 6.522 ± 0.724
0.0ThrMet: 0.0 ± 0.0
2.174ThrAsn: 2.174 ± 0.443
4.348ThrPro: 4.348 ± 1.167
2.899ThrGln: 2.899 ± 0.094
3.623ThrArg: 3.623 ± 0.396
3.623ThrSer: 3.623 ± 1.656
1.449ThrThr: 1.449 ± 0.047
5.797ThrVal: 5.797 ± 0.839
1.449ThrTrp: 1.449 ± 1.073
2.899ThrTyr: 2.899 ± 2.146
0.0ThrXaa: 0.0 ± 0.0
Val
3.623ValAla: 3.623 ± 1.656
0.0ValCys: 0.0 ± 0.0
4.348ValAsp: 4.348 ± 0.141
1.449ValGlu: 1.449 ± 0.047
4.348ValPhe: 4.348 ± 0.141
1.449ValGly: 1.449 ± 1.073
2.899ValHis: 2.899 ± 0.094
2.174ValIle: 2.174 ± 0.583
1.449ValLys: 1.449 ± 0.047
4.348ValLeu: 4.348 ± 0.886
2.174ValMet: 2.174 ± 1.469
1.449ValAsn: 1.449 ± 0.979
6.522ValPro: 6.522 ± 2.776
0.725ValGln: 0.725 ± 0.49
5.072ValArg: 5.072 ± 1.375
5.797ValSer: 5.797 ± 2.24
2.899ValThr: 2.899 ± 0.094
2.174ValVal: 2.174 ± 1.609
0.725ValTrp: 0.725 ± 0.536
2.174ValTyr: 2.174 ± 0.443
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.725TrpCys: 0.725 ± 0.49
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.725TrpPhe: 0.725 ± 0.49
0.725TrpGly: 0.725 ± 0.49
2.174TrpHis: 2.174 ± 0.443
0.725TrpIle: 0.725 ± 0.49
0.725TrpLys: 0.725 ± 0.49
2.899TrpLeu: 2.899 ± 0.094
0.0TrpMet: 0.0 ± 0.0
0.725TrpAsn: 0.725 ± 0.536
2.174TrpPro: 2.174 ± 0.583
0.0TrpGln: 0.0 ± 0.0
0.725TrpArg: 0.725 ± 0.536
2.899TrpSer: 2.899 ± 0.094
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.725TrpTyr: 0.725 ± 0.49
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.348TyrAla: 4.348 ± 0.886
1.449TyrCys: 1.449 ± 0.979
4.348TyrAsp: 4.348 ± 0.886
2.174TyrGlu: 2.174 ± 0.443
2.899TyrPhe: 2.899 ± 0.094
1.449TyrGly: 1.449 ± 0.047
2.899TyrHis: 2.899 ± 0.932
1.449TyrIle: 1.449 ± 0.047
0.725TyrLys: 0.725 ± 0.49
2.899TyrLeu: 2.899 ± 0.094
1.449TyrMet: 1.449 ± 0.047
3.623TyrAsn: 3.623 ± 1.422
2.174TyrPro: 2.174 ± 1.469
1.449TyrGln: 1.449 ± 0.979
1.449TyrArg: 1.449 ± 0.047
3.623TyrSer: 3.623 ± 1.656
3.623TyrThr: 3.623 ± 0.63
4.348TyrVal: 4.348 ± 0.886
0.725TyrTrp: 0.725 ± 0.49
0.725TyrTyr: 0.725 ± 0.536
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1381 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski