Amino acid dipepetide frequency for Wenling frogfish arenavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.588AlaAla: 2.588 ± 1.009
1.15AlaCys: 1.15 ± 0.207
2.876AlaAsp: 2.876 ± 0.282
1.726AlaGlu: 1.726 ± 0.423
2.301AlaPhe: 2.301 ± 1.022
2.876AlaGly: 2.876 ± 0.564
0.0AlaHis: 0.0 ± 0.0
2.301AlaIle: 2.301 ± 0.325
3.164AlaLys: 3.164 ± 1.553
3.739AlaLeu: 3.739 ± 0.911
1.15AlaMet: 1.15 ± 0.363
1.726AlaAsn: 1.726 ± 0.876
1.726AlaPro: 1.726 ± 1.305
0.863AlaGln: 0.863 ± 0.642
2.588AlaArg: 2.588 ± 0.572
4.026AlaSer: 4.026 ± 0.771
1.726AlaThr: 1.726 ± 0.5
3.164AlaVal: 3.164 ± 1.332
0.0AlaTrp: 0.0 ± 0.0
1.438AlaTyr: 1.438 ± 0.494
0.0AlaXaa: 0.0 ± 0.0
Cys
0.863CysAla: 0.863 ± 0.943
0.288CysCys: 0.288 ± 0.171
1.15CysAsp: 1.15 ± 0.399
2.301CysGlu: 2.301 ± 0.548
0.863CysPhe: 0.863 ± 0.305
2.301CysGly: 2.301 ± 1.168
1.15CysHis: 1.15 ± 0.363
2.876CysIle: 2.876 ± 0.903
2.301CysLys: 2.301 ± 0.97
4.314CysLeu: 4.314 ± 1.026
1.438CysMet: 1.438 ± 0.497
1.15CysAsn: 1.15 ± 0.584
0.863CysPro: 0.863 ± 0.512
2.013CysGln: 2.013 ± 0.841
4.026CysArg: 4.026 ± 1.207
2.876CysSer: 2.876 ± 0.642
2.301CysThr: 2.301 ± 1.168
1.15CysVal: 1.15 ± 0.207
0.575CysTrp: 0.575 ± 0.736
0.288CysTyr: 0.288 ± 0.368
0.0CysXaa: 0.0 ± 0.0
Asp
1.438AspAla: 1.438 ± 1.175
1.438AspCys: 1.438 ± 0.517
5.177AspAsp: 5.177 ± 1.511
5.752AspGlu: 5.752 ± 0.73
1.438AspPhe: 1.438 ± 0.53
3.164AspGly: 3.164 ± 0.57
0.863AspHis: 0.863 ± 0.567
4.026AspIle: 4.026 ± 1.207
3.739AspLys: 3.739 ± 0.418
6.903AspLeu: 6.903 ± 1.555
2.301AspMet: 2.301 ± 1.536
3.164AspAsn: 3.164 ± 0.585
3.451AspPro: 3.451 ± 0.717
0.863AspGln: 0.863 ± 0.633
1.726AspArg: 1.726 ± 0.55
7.765AspSer: 7.765 ± 1.41
1.438AspThr: 1.438 ± 0.657
3.164AspVal: 3.164 ± 0.853
0.863AspTrp: 0.863 ± 0.352
1.15AspTyr: 1.15 ± 0.795
0.0AspXaa: 0.0 ± 0.0
Glu
3.739GluAla: 3.739 ± 0.674
3.451GluCys: 3.451 ± 1.366
4.602GluAsp: 4.602 ± 1.087
5.177GluGlu: 5.177 ± 1.773
4.889GluPhe: 4.889 ± 1.231
5.464GluGly: 5.464 ± 0.715
1.726GluHis: 1.726 ± 0.235
5.752GluIle: 5.752 ± 0.804
6.327GluLys: 6.327 ± 0.889
6.615GluLeu: 6.615 ± 1.673
3.451GluMet: 3.451 ± 1.67
2.588GluAsn: 2.588 ± 0.41
2.013GluPro: 2.013 ± 0.386
2.013GluGln: 2.013 ± 1.195
3.451GluArg: 3.451 ± 0.508
3.164GluSer: 3.164 ± 0.425
1.726GluThr: 1.726 ± 0.5
6.04GluVal: 6.04 ± 0.282
1.15GluTrp: 1.15 ± 0.584
0.863GluTyr: 0.863 ± 0.352
0.0GluXaa: 0.0 ± 0.0
Phe
0.575PheAla: 0.575 ± 0.341
0.575PheCys: 0.575 ± 0.736
1.438PheAsp: 1.438 ± 0.904
2.013PheGlu: 2.013 ± 0.78
1.726PhePhe: 1.726 ± 0.235
1.726PheGly: 1.726 ± 0.235
1.15PheHis: 1.15 ± 0.584
3.739PheIle: 3.739 ± 0.453
2.876PheLys: 2.876 ± 1.334
4.026PheLeu: 4.026 ± 1.767
1.726PheMet: 1.726 ± 0.235
1.726PheAsn: 1.726 ± 0.64
0.288PhePro: 0.288 ± 0.171
0.575PheGln: 0.575 ± 0.875
2.013PheArg: 2.013 ± 1.201
3.739PheSer: 3.739 ± 0.861
2.588PheThr: 2.588 ± 0.41
1.15PheVal: 1.15 ± 0.665
1.726PheTrp: 1.726 ± 0.394
1.15PheTyr: 1.15 ± 0.683
0.0PheXaa: 0.0 ± 0.0
Gly
2.301GlyAla: 2.301 ± 0.325
4.314GlyCys: 4.314 ± 0.733
3.739GlyAsp: 3.739 ± 0.773
3.451GlyGlu: 3.451 ± 0.47
0.863GlyPhe: 0.863 ± 0.642
2.876GlyGly: 2.876 ± 0.903
1.15GlyHis: 1.15 ± 0.584
3.164GlyIle: 3.164 ± 0.585
6.903GlyLys: 6.903 ± 0.797
4.889GlyLeu: 4.889 ± 0.865
0.863GlyMet: 0.863 ± 0.567
2.301GlyAsn: 2.301 ± 0.84
1.726GlyPro: 1.726 ± 0.634
2.013GlyGln: 2.013 ± 1.216
5.177GlyArg: 5.177 ± 0.546
2.588GlySer: 2.588 ± 1.161
2.876GlyThr: 2.876 ± 0.903
3.164GlyVal: 3.164 ± 0.348
1.15GlyTrp: 1.15 ± 0.584
0.575GlyTyr: 0.575 ± 0.278
0.0GlyXaa: 0.0 ± 0.0
His
0.288HisAla: 0.288 ± 0.171
0.575HisCys: 0.575 ± 0.278
1.15HisAsp: 1.15 ± 0.363
2.013HisGlu: 2.013 ± 0.841
0.863HisPhe: 0.863 ± 0.275
2.013HisGly: 2.013 ± 1.476
1.15HisHis: 1.15 ± 0.584
1.15HisIle: 1.15 ± 0.683
0.863HisLys: 0.863 ± 0.352
2.876HisLeu: 2.876 ± 1.004
0.288HisMet: 0.288 ± 0.171
1.438HisAsn: 1.438 ± 0.736
1.438HisPro: 1.438 ± 0.572
2.013HisGln: 2.013 ± 1.359
1.726HisArg: 1.726 ± 0.539
2.301HisSer: 2.301 ± 0.662
1.15HisThr: 1.15 ± 0.795
0.863HisVal: 0.863 ± 0.275
0.288HisTrp: 0.288 ± 0.368
0.863HisTyr: 0.863 ± 0.305
0.0HisXaa: 0.0 ± 0.0
Ile
4.026IleAla: 4.026 ± 1.561
2.588IleCys: 2.588 ± 0.31
4.889IleAsp: 4.889 ± 1.935
3.164IleGlu: 3.164 ± 1.052
2.013IlePhe: 2.013 ± 0.669
4.026IleGly: 4.026 ± 1.164
2.301IleHis: 2.301 ± 0.872
2.588IleIle: 2.588 ± 0.695
5.177IleLys: 5.177 ± 1.161
5.464IleLeu: 5.464 ± 0.408
2.301IleMet: 2.301 ± 0.699
3.451IleAsn: 3.451 ± 1.716
2.588IlePro: 2.588 ± 0.715
2.301IleGln: 2.301 ± 1.004
4.314IleArg: 4.314 ± 0.868
5.464IleSer: 5.464 ± 0.835
5.464IleThr: 5.464 ± 1.095
2.301IleVal: 2.301 ± 0.567
0.575IleTrp: 0.575 ± 0.292
1.438IleTyr: 1.438 ± 0.533
0.0IleXaa: 0.0 ± 0.0
Lys
2.588LysAla: 2.588 ± 1.161
2.588LysCys: 2.588 ± 0.47
4.314LysAsp: 4.314 ± 2.761
5.752LysGlu: 5.752 ± 1.765
2.301LysPhe: 2.301 ± 0.755
4.026LysGly: 4.026 ± 0.653
1.438LysHis: 1.438 ± 0.636
5.464LysIle: 5.464 ± 1.641
5.752LysLys: 5.752 ± 1.075
10.066LysLeu: 10.066 ± 1.428
2.301LysMet: 2.301 ± 0.758
2.588LysAsn: 2.588 ± 0.31
2.013LysPro: 2.013 ± 0.386
1.726LysGln: 1.726 ± 0.876
5.752LysArg: 5.752 ± 1.42
7.765LysSer: 7.765 ± 1.727
3.739LysThr: 3.739 ± 1.443
4.602LysVal: 4.602 ± 1.393
1.726LysTrp: 1.726 ± 0.61
1.726LysTyr: 1.726 ± 1.024
0.0LysXaa: 0.0 ± 0.0
Leu
3.451LeuAla: 3.451 ± 1.45
3.164LeuCys: 3.164 ± 1.502
6.04LeuAsp: 6.04 ± 1.656
6.615LeuGlu: 6.615 ± 0.993
5.464LeuPhe: 5.464 ± 0.835
4.026LeuGly: 4.026 ± 0.887
2.876LeuHis: 2.876 ± 0.986
6.903LeuIle: 6.903 ± 1.223
9.491LeuLys: 9.491 ± 1.089
7.765LeuLeu: 7.765 ± 1.8
2.301LeuMet: 2.301 ± 0.548
6.903LeuAsn: 6.903 ± 1.645
5.464LeuPro: 5.464 ± 0.681
2.013LeuGln: 2.013 ± 0.841
4.314LeuArg: 4.314 ± 1.282
8.916LeuSer: 8.916 ± 2.128
4.602LeuThr: 4.602 ± 1.433
4.314LeuVal: 4.314 ± 1.105
1.15LeuTrp: 1.15 ± 0.544
2.301LeuTyr: 2.301 ± 0.548
0.0LeuXaa: 0.0 ± 0.0
Met
1.726MetAla: 1.726 ± 0.394
1.438MetCys: 1.438 ± 0.533
1.438MetAsp: 1.438 ± 1.175
3.739MetGlu: 3.739 ± 1.418
0.863MetPhe: 0.863 ± 0.305
1.438MetGly: 1.438 ± 0.497
0.575MetHis: 0.575 ± 0.593
2.876MetIle: 2.876 ± 0.987
3.451MetLys: 3.451 ± 0.323
2.013MetLeu: 2.013 ± 0.386
2.301MetMet: 2.301 ± 0.662
2.013MetAsn: 2.013 ± 0.69
0.288MetPro: 0.288 ± 0.171
1.15MetGln: 1.15 ± 0.399
3.164MetArg: 3.164 ± 0.512
2.301MetSer: 2.301 ± 0.414
2.588MetThr: 2.588 ± 0.47
1.438MetVal: 1.438 ± 0.854
0.0MetTrp: 0.0 ± 0.0
0.575MetTyr: 0.575 ± 0.278
0.0MetXaa: 0.0 ± 0.0
Asn
2.013AsnAla: 2.013 ± 0.807
1.15AsnCys: 1.15 ± 0.399
1.438AsnAsp: 1.438 ± 1.147
2.876AsnGlu: 2.876 ± 0.593
1.15AsnPhe: 1.15 ± 0.399
2.301AsnGly: 2.301 ± 2.306
2.013AsnHis: 2.013 ± 0.552
2.301AsnIle: 2.301 ± 0.697
2.876AsnLys: 2.876 ± 1.374
3.739AsnLeu: 3.739 ± 0.861
2.876AsnMet: 2.876 ± 0.855
2.013AsnAsn: 2.013 ± 0.561
2.013AsnPro: 2.013 ± 0.386
1.15AsnGln: 1.15 ± 1.047
2.876AsnArg: 2.876 ± 0.562
3.451AsnSer: 3.451 ± 1.198
2.588AsnThr: 2.588 ± 0.695
1.438AsnVal: 1.438 ± 0.657
0.863AsnTrp: 0.863 ± 0.275
1.438AsnTyr: 1.438 ± 0.141
0.0AsnXaa: 0.0 ± 0.0
Pro
1.15ProAla: 1.15 ± 0.399
0.863ProCys: 0.863 ± 0.567
2.588ProAsp: 2.588 ± 0.974
5.752ProGlu: 5.752 ± 0.73
1.438ProPhe: 1.438 ± 0.517
2.013ProGly: 2.013 ± 0.386
1.15ProHis: 1.15 ± 0.363
3.451ProIle: 3.451 ± 0.887
2.876ProLys: 2.876 ± 0.642
4.602ProLeu: 4.602 ± 1.078
0.0ProMet: 0.0 ± 0.0
1.15ProAsn: 1.15 ± 0.544
1.15ProPro: 1.15 ± 0.544
0.575ProGln: 0.575 ± 0.741
0.863ProArg: 0.863 ± 0.305
3.164ProSer: 3.164 ± 1.142
2.301ProThr: 2.301 ± 1.366
1.726ProVal: 1.726 ± 0.55
1.15ProTrp: 1.15 ± 0.544
0.575ProTyr: 0.575 ± 0.341
0.0ProXaa: 0.0 ± 0.0
Gln
1.15GlnAla: 1.15 ± 0.207
0.863GlnCys: 0.863 ± 0.512
1.726GlnAsp: 1.726 ± 0.705
2.013GlnGlu: 2.013 ± 0.367
0.288GlnPhe: 0.288 ± 0.368
2.301GlnGly: 2.301 ± 0.798
0.575GlnHis: 0.575 ± 0.341
1.726GlnIle: 1.726 ± 0.634
2.013GlnLys: 2.013 ± 0.78
3.164GlnLeu: 3.164 ± 1.742
1.726GlnMet: 1.726 ± 0.876
1.438GlnAsn: 1.438 ± 0.497
0.863GlnPro: 0.863 ± 0.642
0.575GlnGln: 0.575 ± 0.736
0.575GlnArg: 0.575 ± 0.292
3.739GlnSer: 3.739 ± 1.001
2.013GlnThr: 2.013 ± 0.669
1.726GlnVal: 1.726 ± 1.199
0.288GlnTrp: 0.288 ± 0.368
0.575GlnTyr: 0.575 ± 0.514
0.0GlnXaa: 0.0 ± 0.0
Arg
3.451ArgAla: 3.451 ± 0.757
1.15ArgCys: 1.15 ± 1.286
4.314ArgAsp: 4.314 ± 1.33
4.314ArgGlu: 4.314 ± 1.341
1.726ArgPhe: 1.726 ± 0.918
2.588ArgGly: 2.588 ± 0.796
1.15ArgHis: 1.15 ± 0.399
2.876ArgIle: 2.876 ± 0.521
4.602ArgLys: 4.602 ± 0.804
6.615ArgLeu: 6.615 ± 2.388
2.301ArgMet: 2.301 ± 0.87
1.15ArgAsn: 1.15 ± 0.855
2.301ArgPro: 2.301 ± 1.115
2.301ArgGln: 2.301 ± 1.62
4.889ArgArg: 4.889 ± 1.203
4.602ArgSer: 4.602 ± 1.173
3.739ArgThr: 3.739 ± 1.054
3.451ArgVal: 3.451 ± 1.221
0.288ArgTrp: 0.288 ± 0.664
2.301ArgTyr: 2.301 ± 0.87
0.0ArgXaa: 0.0 ± 0.0
Ser
4.026SerAla: 4.026 ± 0.743
3.451SerCys: 3.451 ± 1.366
5.177SerAsp: 5.177 ± 0.466
6.04SerGlu: 6.04 ± 0.72
2.301SerPhe: 2.301 ± 0.852
4.602SerGly: 4.602 ± 0.332
2.301SerHis: 2.301 ± 0.534
4.889SerIle: 4.889 ± 1.412
4.314SerLys: 4.314 ± 0.422
9.779SerLeu: 9.779 ± 2.533
3.451SerMet: 3.451 ± 1.366
2.301SerAsn: 2.301 ± 0.325
3.164SerPro: 3.164 ± 1.062
2.301SerGln: 2.301 ± 0.65
5.752SerArg: 5.752 ± 0.762
5.752SerSer: 5.752 ± 1.519
4.026SerThr: 4.026 ± 1.104
6.327SerVal: 6.327 ± 1.093
0.288SerTrp: 0.288 ± 0.371
2.013SerTyr: 2.013 ± 0.884
0.0SerXaa: 0.0 ± 0.0
Thr
2.013ThrAla: 2.013 ± 0.998
1.15ThrCys: 1.15 ± 0.399
1.15ThrAsp: 1.15 ± 0.363
3.451ThrGlu: 3.451 ± 1.306
2.301ThrPhe: 2.301 ± 0.664
4.314ThrGly: 4.314 ± 1.077
1.15ThrHis: 1.15 ± 1.153
2.876ThrIle: 2.876 ± 1.695
3.164ThrLys: 3.164 ± 0.944
4.889ThrLeu: 4.889 ± 0.404
1.438ThrMet: 1.438 ± 0.609
1.438ThrAsn: 1.438 ± 0.736
4.889ThrPro: 4.889 ± 1.262
2.013ThrGln: 2.013 ± 0.318
2.876ThrArg: 2.876 ± 0.883
3.739ThrSer: 3.739 ± 0.579
2.301ThrThr: 2.301 ± 1.173
2.876ThrVal: 2.876 ± 0.883
0.863ThrTrp: 0.863 ± 0.633
0.863ThrTyr: 0.863 ± 0.275
0.0ThrXaa: 0.0 ± 0.0
Val
2.301ValAla: 2.301 ± 0.428
3.164ValCys: 3.164 ± 0.681
3.739ValAsp: 3.739 ± 0.579
4.314ValGlu: 4.314 ± 0.609
2.301ValPhe: 2.301 ± 0.414
1.15ValGly: 1.15 ± 1.005
1.438ValHis: 1.438 ± 0.53
4.314ValIle: 4.314 ± 0.689
6.327ValLys: 6.327 ± 0.641
3.739ValLeu: 3.739 ± 1.44
1.438ValMet: 1.438 ± 1.015
2.876ValAsn: 2.876 ± 0.642
2.013ValPro: 2.013 ± 0.621
2.013ValGln: 2.013 ± 0.998
2.588ValArg: 2.588 ± 0.796
3.451ValSer: 3.451 ± 0.888
2.013ValThr: 2.013 ± 0.669
2.876ValVal: 2.876 ± 1.004
1.15ValTrp: 1.15 ± 0.683
1.438ValTyr: 1.438 ± 0.141
0.0ValXaa: 0.0 ± 0.0
Trp
1.15TrpAla: 1.15 ± 0.683
0.288TrpCys: 0.288 ± 0.368
0.863TrpAsp: 0.863 ± 0.766
1.438TrpGlu: 1.438 ± 0.533
0.288TrpPhe: 0.288 ± 0.368
1.438TrpGly: 1.438 ± 0.572
0.0TrpHis: 0.0 ± 0.0
1.438TrpIle: 1.438 ± 0.141
1.15TrpLys: 1.15 ± 0.363
0.863TrpLeu: 0.863 ± 0.642
0.863TrpMet: 0.863 ± 0.567
0.863TrpAsn: 0.863 ± 1.105
0.288TrpPro: 0.288 ± 0.664
0.288TrpGln: 0.288 ± 0.371
0.288TrpArg: 0.288 ± 0.368
0.863TrpSer: 0.863 ± 0.305
0.0TrpThr: 0.0 ± 0.0
1.726TrpVal: 1.726 ± 0.705
0.0TrpTrp: 0.0 ± 0.0
0.288TrpTyr: 0.288 ± 0.371
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.288TyrAla: 0.288 ± 0.371
1.438TyrCys: 1.438 ± 1.013
2.013TyrAsp: 2.013 ± 0.841
2.301TyrGlu: 2.301 ± 0.414
1.15TyrPhe: 1.15 ± 0.363
1.438TyrGly: 1.438 ± 0.497
1.15TyrHis: 1.15 ± 0.584
1.726TyrIle: 1.726 ± 0.423
1.15TyrLys: 1.15 ± 0.683
2.013TyrLeu: 2.013 ± 0.884
0.575TyrMet: 0.575 ± 0.593
0.288TyrAsn: 0.288 ± 0.368
0.0TyrPro: 0.0 ± 0.0
0.575TyrGln: 0.575 ± 0.341
1.15TyrArg: 1.15 ± 0.399
2.588TyrSer: 2.588 ± 0.926
0.575TyrThr: 0.575 ± 0.593
1.15TyrVal: 1.15 ± 0.207
0.288TyrTrp: 0.288 ± 0.171
0.288TyrTyr: 0.288 ± 0.368
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3478 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski