Amino acid dipepetide frequency for Spider associated circular virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.264AlaAla: 8.264 ± 1.009
1.653AlaCys: 1.653 ± 1.248
0.0AlaAsp: 0.0 ± 0.0
3.306AlaGlu: 3.306 ± 2.497
3.306AlaPhe: 3.306 ± 0.08
1.653AlaGly: 1.653 ± 1.168
0.0AlaHis: 0.0 ± 0.0
6.612AlaIle: 6.612 ± 2.577
8.264AlaLys: 8.264 ± 1.408
8.264AlaLeu: 8.264 ± 1.408
1.653AlaMet: 1.653 ± 1.168
8.264AlaAsn: 8.264 ± 1.408
0.0AlaPro: 0.0 ± 0.0
4.959AlaGln: 4.959 ± 1.328
9.917AlaArg: 9.917 ± 2.177
3.306AlaSer: 3.306 ± 0.08
3.306AlaThr: 3.306 ± 2.337
1.653AlaVal: 1.653 ± 1.168
3.306AlaTrp: 3.306 ± 2.497
3.306AlaTyr: 3.306 ± 0.08
0.0AlaXaa: 0.0 ± 0.0
Cys
1.653CysAla: 1.653 ± 1.168
0.0CysCys: 0.0 ± 0.0
3.306CysAsp: 3.306 ± 2.497
0.0CysGlu: 0.0 ± 0.0
3.306CysPhe: 3.306 ± 0.08
1.653CysGly: 1.653 ± 1.248
0.0CysHis: 0.0 ± 0.0
1.653CysIle: 1.653 ± 1.248
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.653CysAsn: 1.653 ± 1.248
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
3.306CysThr: 3.306 ± 0.08
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.612AspAla: 6.612 ± 0.16
0.0AspCys: 0.0 ± 0.0
6.612AspAsp: 6.612 ± 2.577
1.653AspGlu: 1.653 ± 1.168
1.653AspPhe: 1.653 ± 1.248
8.264AspGly: 8.264 ± 3.825
1.653AspHis: 1.653 ± 1.248
4.959AspIle: 4.959 ± 1.328
1.653AspLys: 1.653 ± 1.168
1.653AspLeu: 1.653 ± 1.168
0.0AspMet: 0.0 ± 0.0
3.306AspAsn: 3.306 ± 2.337
3.306AspPro: 3.306 ± 2.497
4.959AspGln: 4.959 ± 1.089
3.306AspArg: 3.306 ± 2.497
0.0AspSer: 0.0 ± 0.0
3.306AspThr: 3.306 ± 0.08
9.917AspVal: 9.917 ± 2.656
3.306AspTrp: 3.306 ± 0.08
3.306AspTyr: 3.306 ± 0.08
0.0AspXaa: 0.0 ± 0.0
Glu
4.959GluAla: 4.959 ± 1.089
1.653GluCys: 1.653 ± 1.248
1.653GluAsp: 1.653 ± 1.168
3.306GluGlu: 3.306 ± 2.497
1.653GluPhe: 1.653 ± 1.248
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
3.306GluIle: 3.306 ± 0.08
3.306GluLys: 3.306 ± 2.337
6.612GluLeu: 6.612 ± 2.577
1.653GluMet: 1.653 ± 0.837
1.653GluAsn: 1.653 ± 1.248
4.959GluPro: 4.959 ± 3.745
1.653GluGln: 1.653 ± 1.248
3.306GluArg: 3.306 ± 2.497
3.306GluSer: 3.306 ± 0.08
1.653GluThr: 1.653 ± 1.168
3.306GluVal: 3.306 ± 2.497
3.306GluTrp: 3.306 ± 2.497
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.653PheAla: 1.653 ± 1.168
0.0PheCys: 0.0 ± 0.0
4.959PheAsp: 4.959 ± 1.328
3.306PheGlu: 3.306 ± 0.08
1.653PhePhe: 1.653 ± 1.248
0.0PheGly: 0.0 ± 0.0
0.0PheHis: 0.0 ± 0.0
4.959PheIle: 4.959 ± 1.328
4.959PheLys: 4.959 ± 1.089
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
1.653PheAsn: 1.653 ± 1.248
1.653PhePro: 1.653 ± 1.248
1.653PheGln: 1.653 ± 1.248
9.917PheArg: 9.917 ± 2.656
1.653PheSer: 1.653 ± 1.168
1.653PheThr: 1.653 ± 1.168
3.306PheVal: 3.306 ± 0.08
1.653PheTrp: 1.653 ± 1.248
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.306GlyAla: 3.306 ± 2.497
0.0GlyCys: 0.0 ± 0.0
4.959GlyAsp: 4.959 ± 1.328
3.306GlyGlu: 3.306 ± 0.08
3.306GlyPhe: 3.306 ± 0.08
21.488GlyGly: 21.488 ± 0.689
0.0GlyHis: 0.0 ± 0.0
6.612GlyIle: 6.612 ± 4.993
3.306GlyLys: 3.306 ± 0.08
6.612GlyLeu: 6.612 ± 0.16
3.306GlyMet: 3.306 ± 2.337
3.306GlyAsn: 3.306 ± 2.337
1.653GlyPro: 1.653 ± 1.168
6.612GlyGln: 6.612 ± 2.257
3.306GlyArg: 3.306 ± 2.497
4.959GlySer: 4.959 ± 1.089
4.959GlyThr: 4.959 ± 3.505
0.0GlyVal: 0.0 ± 0.0
1.653GlyTrp: 1.653 ± 1.168
1.653GlyTyr: 1.653 ± 1.248
0.0GlyXaa: 0.0 ± 0.0
His
1.653HisAla: 1.653 ± 1.248
1.653HisCys: 1.653 ± 1.248
0.0HisAsp: 0.0 ± 0.0
1.653HisGlu: 1.653 ± 1.168
1.653HisPhe: 1.653 ± 1.248
1.653HisGly: 1.653 ± 1.248
1.653HisHis: 1.653 ± 1.248
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
4.959HisLeu: 4.959 ± 3.745
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
3.306HisPro: 3.306 ± 0.08
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
3.306IleCys: 3.306 ± 0.08
0.0IleAsp: 0.0 ± 0.0
4.959IleGlu: 4.959 ± 1.328
4.959IlePhe: 4.959 ± 3.745
4.959IleGly: 4.959 ± 1.089
1.653IleHis: 1.653 ± 1.248
1.653IleIle: 1.653 ± 1.248
4.959IleLys: 4.959 ± 3.745
3.306IleLeu: 3.306 ± 2.337
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
1.653IleGln: 1.653 ± 1.168
4.959IleArg: 4.959 ± 1.328
4.959IleSer: 4.959 ± 1.089
3.306IleThr: 3.306 ± 0.08
1.653IleVal: 1.653 ± 1.248
1.653IleTrp: 1.653 ± 1.248
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.959LysAla: 4.959 ± 1.328
0.0LysCys: 0.0 ± 0.0
3.306LysAsp: 3.306 ± 2.497
4.959LysGlu: 4.959 ± 1.328
3.306LysPhe: 3.306 ± 2.497
3.306LysGly: 3.306 ± 2.337
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
6.612LysLys: 6.612 ± 2.257
1.653LysLeu: 1.653 ± 1.168
0.0LysMet: 0.0 ± 0.808
0.0LysAsn: 0.0 ± 0.0
3.306LysPro: 3.306 ± 0.08
0.0LysGln: 0.0 ± 0.0
8.264LysArg: 8.264 ± 3.425
1.653LysSer: 1.653 ± 1.168
3.306LysThr: 3.306 ± 2.337
1.653LysVal: 1.653 ± 1.168
3.306LysTrp: 3.306 ± 0.08
8.264LysTyr: 8.264 ± 1.408
0.0LysXaa: 0.0 ± 0.0
Leu
6.612LeuAla: 6.612 ± 0.16
0.0LeuCys: 0.0 ± 0.0
4.959LeuAsp: 4.959 ± 1.328
3.306LeuGlu: 3.306 ± 2.497
4.959LeuPhe: 4.959 ± 3.505
4.959LeuGly: 4.959 ± 1.089
1.653LeuHis: 1.653 ± 1.248
1.653LeuIle: 1.653 ± 1.248
4.959LeuLys: 4.959 ± 1.089
3.306LeuLeu: 3.306 ± 0.08
0.0LeuMet: 0.0 ± 0.0
1.653LeuAsn: 1.653 ± 1.168
0.0LeuPro: 0.0 ± 0.0
0.0LeuGln: 0.0 ± 0.0
0.0LeuArg: 0.0 ± 0.0
3.306LeuSer: 3.306 ± 0.08
6.612LeuThr: 6.612 ± 2.257
6.612LeuVal: 6.612 ± 0.16
1.653LeuTrp: 1.653 ± 1.168
3.306LeuTyr: 3.306 ± 0.08
0.0LeuXaa: 0.0 ± 0.0
Met
1.653MetAla: 1.653 ± 1.168
0.0MetCys: 0.0 ± 0.0
1.653MetAsp: 1.653 ± 1.248
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
3.306MetGly: 3.306 ± 0.08
0.0MetHis: 0.0 ± 0.0
1.653MetIle: 1.653 ± 1.168
0.0MetLys: 0.0 ± 0.0
1.653MetLeu: 1.653 ± 1.168
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.306MetPro: 3.306 ± 0.08
0.0MetGln: 0.0 ± 0.0
1.653MetArg: 1.653 ± 1.168
0.0MetSer: 0.0 ± 0.0
3.306MetThr: 3.306 ± 2.337
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.306AsnAla: 3.306 ± 2.497
1.653AsnCys: 1.653 ± 1.248
8.264AsnAsp: 8.264 ± 1.009
1.653AsnGlu: 1.653 ± 1.168
1.653AsnPhe: 1.653 ± 1.248
4.959AsnGly: 4.959 ± 1.089
1.653AsnHis: 1.653 ± 1.248
3.306AsnIle: 3.306 ± 0.08
1.653AsnLys: 1.653 ± 1.168
1.653AsnLeu: 1.653 ± 1.168
0.0AsnMet: 0.0 ± 0.0
1.653AsnAsn: 1.653 ± 1.168
1.653AsnPro: 1.653 ± 1.168
0.0AsnGln: 0.0 ± 0.0
3.306AsnArg: 3.306 ± 2.337
1.653AsnSer: 1.653 ± 1.168
6.612AsnThr: 6.612 ± 2.257
1.653AsnVal: 1.653 ± 1.168
0.0AsnTrp: 0.0 ± 0.0
1.653AsnTyr: 1.653 ± 1.248
0.0AsnXaa: 0.0 ± 0.0
Pro
6.612ProAla: 6.612 ± 2.577
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
3.306ProGlu: 3.306 ± 0.08
1.653ProPhe: 1.653 ± 1.248
3.306ProGly: 3.306 ± 0.08
0.0ProHis: 0.0 ± 0.0
1.653ProIle: 1.653 ± 1.168
1.653ProLys: 1.653 ± 1.248
1.653ProLeu: 1.653 ± 1.248
1.653ProMet: 1.653 ± 1.168
1.653ProAsn: 1.653 ± 1.248
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
3.306ProArg: 3.306 ± 2.497
1.653ProSer: 1.653 ± 1.248
3.306ProThr: 3.306 ± 2.337
0.0ProVal: 0.0 ± 0.0
3.306ProTrp: 3.306 ± 0.08
3.306ProTyr: 3.306 ± 2.337
0.0ProXaa: 0.0 ± 0.0
Gln
4.959GlnAla: 4.959 ± 1.328
1.653GlnCys: 1.653 ± 1.248
3.306GlnAsp: 3.306 ± 2.337
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
1.653GlnGly: 1.653 ± 1.168
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
3.306GlnLeu: 3.306 ± 0.08
0.0GlnMet: 0.0 ± 0.0
3.306GlnAsn: 3.306 ± 2.337
0.0GlnPro: 0.0 ± 0.0
1.653GlnGln: 1.653 ± 1.168
0.0GlnArg: 0.0 ± 0.0
3.306GlnSer: 3.306 ± 2.497
0.0GlnThr: 0.0 ± 0.0
3.306GlnVal: 3.306 ± 2.337
1.653GlnTrp: 1.653 ± 1.168
1.653GlnTyr: 1.653 ± 1.168
0.0GlnXaa: 0.0 ± 0.0
Arg
4.959ArgAla: 4.959 ± 1.089
0.0ArgCys: 0.0 ± 0.0
8.264ArgAsp: 8.264 ± 1.408
3.306ArgGlu: 3.306 ± 2.497
3.306ArgPhe: 3.306 ± 0.08
3.306ArgGly: 3.306 ± 0.08
1.653ArgHis: 1.653 ± 1.248
3.306ArgIle: 3.306 ± 2.337
4.959ArgLys: 4.959 ± 1.089
1.653ArgLeu: 1.653 ± 1.168
0.0ArgMet: 0.0 ± 0.0
3.306ArgAsn: 3.306 ± 0.08
6.612ArgPro: 6.612 ± 2.257
0.0ArgGln: 0.0 ± 0.0
11.57ArgArg: 11.57 ± 5.762
9.917ArgSer: 9.917 ± 5.073
8.264ArgThr: 8.264 ± 3.425
4.959ArgVal: 4.959 ± 1.328
0.0ArgTrp: 0.0 ± 0.0
3.306ArgTyr: 3.306 ± 0.08
0.0ArgXaa: 0.0 ± 0.0
Ser
1.653SerAla: 1.653 ± 1.168
0.0SerCys: 0.0 ± 0.0
4.959SerAsp: 4.959 ± 1.089
0.0SerGlu: 0.0 ± 0.0
3.306SerPhe: 3.306 ± 2.337
6.612SerGly: 6.612 ± 2.577
1.653SerHis: 1.653 ± 1.248
1.653SerIle: 1.653 ± 1.248
4.959SerLys: 4.959 ± 1.089
0.0SerLeu: 0.0 ± 0.0
0.0SerMet: 0.0 ± 0.0
3.306SerAsn: 3.306 ± 0.08
3.306SerPro: 3.306 ± 2.497
1.653SerGln: 1.653 ± 1.168
6.612SerArg: 6.612 ± 0.16
6.612SerSer: 6.612 ± 2.257
9.917SerThr: 9.917 ± 7.011
1.653SerVal: 1.653 ± 1.168
1.653SerTrp: 1.653 ± 1.248
1.653SerTyr: 1.653 ± 1.248
0.0SerXaa: 0.0 ± 0.0
Thr
6.612ThrAla: 6.612 ± 4.674
1.653ThrCys: 1.653 ± 1.168
3.306ThrAsp: 3.306 ± 0.08
6.612ThrGlu: 6.612 ± 2.577
3.306ThrPhe: 3.306 ± 0.08
6.612ThrGly: 6.612 ± 4.674
0.0ThrHis: 0.0 ± 0.0
1.653ThrIle: 1.653 ± 1.168
1.653ThrLys: 1.653 ± 1.168
6.612ThrLeu: 6.612 ± 4.674
3.306ThrMet: 3.306 ± 2.337
3.306ThrAsn: 3.306 ± 0.08
3.306ThrPro: 3.306 ± 0.08
3.306ThrGln: 3.306 ± 2.337
1.653ThrArg: 1.653 ± 1.168
9.917ThrSer: 9.917 ± 7.011
3.306ThrThr: 3.306 ± 2.337
1.653ThrVal: 1.653 ± 1.248
0.0ThrTrp: 0.0 ± 0.0
6.612ThrTyr: 6.612 ± 2.257
0.0ThrXaa: 0.0 ± 0.0
Val
1.653ValAla: 1.653 ± 1.248
0.0ValCys: 0.0 ± 0.0
6.612ValAsp: 6.612 ± 2.577
3.306ValGlu: 3.306 ± 2.497
1.653ValPhe: 1.653 ± 1.168
0.0ValGly: 0.0 ± 0.0
3.306ValHis: 3.306 ± 2.497
1.653ValIle: 1.653 ± 1.248
4.959ValLys: 4.959 ± 1.328
3.306ValLeu: 3.306 ± 2.337
1.653ValMet: 1.653 ± 1.248
3.306ValAsn: 3.306 ± 2.337
1.653ValPro: 1.653 ± 1.168
0.0ValGln: 0.0 ± 0.0
3.306ValArg: 3.306 ± 2.337
4.959ValSer: 4.959 ± 1.089
4.959ValThr: 4.959 ± 1.328
0.0ValVal: 0.0 ± 0.0
0.0ValTrp: 0.0 ± 0.0
1.653ValTyr: 1.653 ± 1.168
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
3.306TrpCys: 3.306 ± 0.08
0.0TrpAsp: 0.0 ± 0.0
1.653TrpGlu: 1.653 ± 1.248
0.0TrpPhe: 0.0 ± 0.0
3.306TrpGly: 3.306 ± 2.497
3.306TrpHis: 3.306 ± 2.337
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
3.306TrpLeu: 3.306 ± 2.497
1.653TrpMet: 1.653 ± 1.248
3.306TrpAsn: 3.306 ± 0.08
0.0TrpPro: 0.0 ± 0.0
1.653TrpGln: 1.653 ± 1.168
3.306TrpArg: 3.306 ± 0.08
0.0TrpSer: 0.0 ± 0.0
1.653TrpThr: 1.653 ± 1.248
1.653TrpVal: 1.653 ± 1.168
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
9.917TyrAla: 9.917 ± 5.073
0.0TyrCys: 0.0 ± 0.0
3.306TyrAsp: 3.306 ± 0.08
1.653TyrGlu: 1.653 ± 1.248
0.0TyrPhe: 0.0 ± 0.0
3.306TyrGly: 3.306 ± 0.08
0.0TyrHis: 0.0 ± 0.0
1.653TyrIle: 1.653 ± 1.168
1.653TyrLys: 1.653 ± 1.168
0.0TyrLeu: 0.0 ± 0.0
1.653TyrMet: 1.653 ± 1.168
3.306TyrAsn: 3.306 ± 2.337
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
4.959TyrArg: 4.959 ± 1.089
0.0TyrSer: 0.0 ± 0.0
1.653TyrThr: 1.653 ± 1.168
4.959TyrVal: 4.959 ± 1.328
1.653TyrTrp: 1.653 ± 1.168
1.653TyrTyr: 1.653 ± 1.168
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (606 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski