Xylaria hypoxylon

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; sordariomyceta; Sordariomycetes; Xylariomycetidae; Xylariales; Xylariaceae; Xylaria

Average proteome isoelectric point is 6.29

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 11037 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A4Z0Z8W8|A0A4Z0Z8W8_9PEZI tRNA wybutosine-synthesizing protein 4 OS=Xylaria hypoxylon OX=37992 GN=E0Z10_g2906 PE=4 SV=1
MM1 pKa = 7.55TKK3 pKa = 10.0PNEE6 pKa = 4.42AIAVVVTVLILGGFIAFYY24 pKa = 10.95VFTYY28 pKa = 9.61CFRR31 pKa = 11.84HH32 pKa = 6.65SGDD35 pKa = 5.32DD36 pKa = 5.33DD37 pKa = 6.68DD38 pKa = 7.69DD39 pKa = 7.31DD40 pKa = 7.65DD41 pKa = 6.89DD42 pKa = 6.71DD43 pKa = 5.51EE44 pKa = 4.98YY45 pKa = 11.88NNDD48 pKa = 3.32YY49 pKa = 11.08GAVGSSAFLSTSTSTSAGEE68 pKa = 4.11PGDD71 pKa = 4.58GILRR75 pKa = 11.84PPPVVFAQSGRR86 pKa = 11.84SQYY89 pKa = 10.69PPANTSFPIGTDD101 pKa = 3.35TVPDD105 pKa = 4.61LPYY108 pKa = 10.45QDD110 pKa = 4.75NGTAAGGAGSHH121 pKa = 6.31GNGVGIAEE129 pKa = 4.65GTSGTPPPPAVDD141 pKa = 3.52VEE143 pKa = 4.43HH144 pKa = 7.34PDD146 pKa = 3.94DD147 pKa = 4.7RR148 pKa = 11.84GG149 pKa = 3.18

Molecular weight: 15.31 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A4Z0YLJ0|A0A4Z0YLJ0_9PEZI GATA-type domain-containing protein OS=Xylaria hypoxylon OX=37992 GN=E0Z10_g8450 PE=4 SV=1
MM1 pKa = 7.05MSSFRR6 pKa = 11.84GLCLLRR12 pKa = 11.84ATQTRR17 pKa = 11.84PSHH20 pKa = 6.18IPSSLHH26 pKa = 6.0LRR28 pKa = 11.84PSSITSRR35 pKa = 11.84ISPSPLHH42 pKa = 6.95HH43 pKa = 6.43IQQHH47 pKa = 4.74GRR49 pKa = 11.84RR50 pKa = 11.84SFHH53 pKa = 5.54WQSAASTTIEE63 pKa = 4.12GAQNLIVDD71 pKa = 4.35LHH73 pKa = 6.12TVTSLPWFLTIPLVAFTVGAVFRR96 pKa = 11.84LPFSIYY102 pKa = 7.03TQRR105 pKa = 11.84ILQRR109 pKa = 11.84RR110 pKa = 11.84TNFGPLLQAWNARR123 pKa = 11.84IQQDD127 pKa = 3.76VQQEE131 pKa = 4.69GISASSRR138 pKa = 11.84MSEE141 pKa = 3.8VKK143 pKa = 10.35ARR145 pKa = 11.84QDD147 pKa = 3.03KK148 pKa = 10.11ALKK151 pKa = 10.15RR152 pKa = 11.84IYY154 pKa = 10.18RR155 pKa = 11.84KK156 pKa = 10.25LGLQEE161 pKa = 3.1WRR163 pKa = 11.84MWGSILSFPIWLVAIDD179 pKa = 3.89AVRR182 pKa = 11.84RR183 pKa = 11.84LCGGPRR189 pKa = 11.84GLIGSLFIGPGSSSEE204 pKa = 4.29TTVAAHH210 pKa = 6.15VEE212 pKa = 4.38AASSLPPGSVADD224 pKa = 4.58PSTLDD229 pKa = 3.37PVAISSAVEE238 pKa = 3.93TAHH241 pKa = 6.51MATVDD246 pKa = 3.61PSLTLEE252 pKa = 4.24GCLWFTDD259 pKa = 3.98LTASDD264 pKa = 5.15PYY266 pKa = 11.41HH267 pKa = 6.45MLPIALSVTLVLNMLPKK284 pKa = 10.4SGEE287 pKa = 4.0KK288 pKa = 10.4FSDD291 pKa = 3.12RR292 pKa = 11.84VRR294 pKa = 11.84IALGRR299 pKa = 11.84RR300 pKa = 11.84PKK302 pKa = 10.27SARR305 pKa = 11.84AQTFAGDD312 pKa = 3.53EE313 pKa = 4.07KK314 pKa = 11.09VGFRR318 pKa = 11.84EE319 pKa = 3.77RR320 pKa = 11.84LFATFYY326 pKa = 10.76LCMVGVATLVGPLTLDD342 pKa = 3.76LPAALHH348 pKa = 6.28LYY350 pKa = 8.69WLASSMSNVLFMKK363 pKa = 10.21GLRR366 pKa = 11.84HH367 pKa = 6.05LMPVEE372 pKa = 3.81GRR374 pKa = 11.84LLKK377 pKa = 10.51RR378 pKa = 11.84CTGAEE383 pKa = 3.99FPVIRR388 pKa = 11.84PQRR391 pKa = 11.84QQKK394 pKa = 8.86NN395 pKa = 3.3

Molecular weight: 43.67 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

11037

0

11037

5574772

35

6685

505.1

55.9

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.488 ± 0.016

1.137 ± 0.008

5.876 ± 0.016

6.112 ± 0.022

3.725 ± 0.013

6.855 ± 0.02

2.398 ± 0.009

5.137 ± 0.014

4.767 ± 0.02

8.912 ± 0.024

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.067 ± 0.009

3.843 ± 0.012

5.932 ± 0.023

3.957 ± 0.014

5.998 ± 0.018

8.24 ± 0.024

6.141 ± 0.014

6.142 ± 0.014

1.465 ± 0.009

2.809 ± 0.01
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski