Amino acid dipepetide frequency for Beihai narna-like virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.456AlaAla: 14.456 ± 7.82
0.0AlaCys: 0.0 ± 0.0
6.803AlaAsp: 6.803 ± 0.427
2.551AlaGlu: 2.551 ± 0.163
5.102AlaPhe: 5.102 ± 0.326
5.102AlaGly: 5.102 ± 1.619
0.85AlaHis: 0.85 ± 0.916
1.701AlaIle: 1.701 ± 0.54
5.102AlaLys: 5.102 ± 2.259
17.007AlaLeu: 17.007 ± 0.226
0.0AlaMet: 0.0 ± 0.0
2.551AlaAsn: 2.551 ± 0.163
0.85AlaPro: 0.85 ± 0.916
1.701AlaGln: 1.701 ± 0.54
4.252AlaArg: 4.252 ± 0.703
5.102AlaSer: 5.102 ± 0.326
6.803AlaThr: 6.803 ± 0.427
4.252AlaVal: 4.252 ± 0.703
0.85AlaTrp: 0.85 ± 0.377
4.252AlaTyr: 4.252 ± 0.59
0.0AlaXaa: 0.0 ± 0.0
Cys
1.701CysAla: 1.701 ± 0.753
0.0CysCys: 0.0 ± 0.0
1.701CysAsp: 1.701 ± 0.753
0.0CysGlu: 0.0 ± 0.0
0.85CysPhe: 0.85 ± 0.377
0.85CysGly: 0.85 ± 0.377
0.85CysHis: 0.85 ± 0.377
0.85CysIle: 0.85 ± 0.377
0.0CysLys: 0.0 ± 0.0
1.701CysLeu: 1.701 ± 0.753
0.0CysMet: 0.0 ± 0.0
0.85CysAsn: 0.85 ± 0.377
0.85CysPro: 0.85 ± 0.377
0.0CysGln: 0.0 ± 0.0
2.551CysArg: 2.551 ± 0.163
3.401CysSer: 3.401 ± 1.08
1.701CysThr: 1.701 ± 0.753
0.85CysVal: 0.85 ± 0.916
0.0CysTrp: 0.0 ± 0.0
0.85CysTyr: 0.85 ± 0.377
0.0CysXaa: 0.0 ± 0.0
Asp
6.803AspAla: 6.803 ± 1.719
0.0AspCys: 0.0 ± 0.0
3.401AspAsp: 3.401 ± 0.213
0.85AspGlu: 0.85 ± 0.377
2.551AspPhe: 2.551 ± 1.13
2.551AspGly: 2.551 ± 0.163
0.85AspHis: 0.85 ± 0.377
1.701AspIle: 1.701 ± 0.54
0.0AspLys: 0.0 ± 0.0
5.102AspLeu: 5.102 ± 2.259
0.0AspMet: 0.0 ± 0.0
1.701AspAsn: 1.701 ± 0.753
5.952AspPro: 5.952 ± 0.05
0.85AspGln: 0.85 ± 0.377
1.701AspArg: 1.701 ± 0.753
4.252AspSer: 4.252 ± 1.996
0.85AspThr: 0.85 ± 0.377
4.252AspVal: 4.252 ± 0.59
0.85AspTrp: 0.85 ± 0.377
3.401AspTyr: 3.401 ± 1.506
0.0AspXaa: 0.0 ± 0.0
Glu
2.551GluAla: 2.551 ± 1.456
2.551GluCys: 2.551 ± 1.13
1.701GluAsp: 1.701 ± 0.54
5.102GluGlu: 5.102 ± 2.259
2.551GluPhe: 2.551 ± 0.163
3.401GluGly: 3.401 ± 0.213
1.701GluHis: 1.701 ± 0.753
0.85GluIle: 0.85 ± 0.377
0.85GluLys: 0.85 ± 0.377
3.401GluLeu: 3.401 ± 0.213
0.85GluMet: 0.85 ± 0.377
2.551GluAsn: 2.551 ± 1.13
2.551GluPro: 2.551 ± 1.13
0.85GluGln: 0.85 ± 0.377
5.952GluArg: 5.952 ± 1.343
2.551GluSer: 2.551 ± 0.163
1.701GluThr: 1.701 ± 0.753
1.701GluVal: 1.701 ± 0.753
3.401GluTrp: 3.401 ± 0.213
1.701GluTyr: 1.701 ± 1.833
0.0GluXaa: 0.0 ± 0.0
Phe
2.551PheAla: 2.551 ± 0.163
0.85PheCys: 0.85 ± 0.916
1.701PheAsp: 1.701 ± 0.54
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
4.252PheGly: 4.252 ± 1.883
0.0PheHis: 0.0 ± 0.0
1.701PheIle: 1.701 ± 0.753
0.85PheLys: 0.85 ± 0.377
5.102PheLeu: 5.102 ± 2.259
0.85PheMet: 0.85 ± 0.377
2.551PheAsn: 2.551 ± 2.749
2.551PhePro: 2.551 ± 0.163
2.551PheGln: 2.551 ± 0.163
2.551PheArg: 2.551 ± 1.13
4.252PheSer: 4.252 ± 0.703
2.551PheThr: 2.551 ± 0.163
3.401PheVal: 3.401 ± 0.213
0.0PheTrp: 0.0 ± 0.0
0.85PheTyr: 0.85 ± 0.377
0.0PheXaa: 0.0 ± 0.0
Gly
5.952GlyAla: 5.952 ± 2.536
1.701GlyCys: 1.701 ± 0.753
3.401GlyAsp: 3.401 ± 1.506
2.551GlyGlu: 2.551 ± 1.13
3.401GlyPhe: 3.401 ± 1.08
3.401GlyGly: 3.401 ± 1.08
1.701GlyHis: 1.701 ± 0.54
5.102GlyIle: 5.102 ± 2.912
4.252GlyLys: 4.252 ± 0.59
5.952GlyLeu: 5.952 ± 0.05
0.0GlyMet: 0.0 ± 0.0
3.401GlyAsn: 3.401 ± 1.08
4.252GlyPro: 4.252 ± 0.703
3.401GlyGln: 3.401 ± 0.213
5.952GlyArg: 5.952 ± 0.05
7.653GlySer: 7.653 ± 2.096
2.551GlyThr: 2.551 ± 1.456
5.952GlyVal: 5.952 ± 2.536
0.85GlyTrp: 0.85 ± 0.377
2.551GlyTyr: 2.551 ± 0.163
0.0GlyXaa: 0.0 ± 0.0
His
1.701HisAla: 1.701 ± 0.54
0.0HisCys: 0.0 ± 0.0
0.85HisAsp: 0.85 ± 0.377
0.85HisGlu: 0.85 ± 0.377
0.85HisPhe: 0.85 ± 0.377
0.0HisGly: 0.0 ± 0.0
0.85HisHis: 0.85 ± 0.916
0.0HisIle: 0.0 ± 0.0
0.85HisLys: 0.85 ± 0.377
5.952HisLeu: 5.952 ± 0.05
0.0HisMet: 0.0 ± 0.0
1.701HisAsn: 1.701 ± 0.753
1.701HisPro: 1.701 ± 1.833
0.85HisGln: 0.85 ± 0.377
0.85HisArg: 0.85 ± 0.377
1.701HisSer: 1.701 ± 0.753
0.0HisThr: 0.0 ± 0.0
0.85HisVal: 0.85 ± 0.916
0.0HisTrp: 0.0 ± 0.0
1.701HisTyr: 1.701 ± 0.753
0.0HisXaa: 0.0 ± 0.0
Ile
1.701IleAla: 1.701 ± 0.54
0.85IleCys: 0.85 ± 0.377
2.551IleAsp: 2.551 ± 0.163
2.551IleGlu: 2.551 ± 2.749
0.0IlePhe: 0.0 ± 0.0
1.701IleGly: 1.701 ± 0.753
1.701IleHis: 1.701 ± 0.753
0.85IleIle: 0.85 ± 0.916
1.701IleLys: 1.701 ± 0.54
2.551IleLeu: 2.551 ± 1.13
0.0IleMet: 0.0 ± 0.0
3.401IleAsn: 3.401 ± 0.213
5.102IlePro: 5.102 ± 1.619
0.0IleGln: 0.0 ± 0.0
0.85IleArg: 0.85 ± 0.377
2.551IleSer: 2.551 ± 1.13
0.85IleThr: 0.85 ± 0.377
0.85IleVal: 0.85 ± 0.916
0.85IleTrp: 0.85 ± 0.377
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.551LysAla: 2.551 ± 1.13
1.701LysCys: 1.701 ± 0.753
0.85LysAsp: 0.85 ± 0.377
0.85LysGlu: 0.85 ± 0.377
2.551LysPhe: 2.551 ± 1.13
0.0LysGly: 0.0 ± 0.0
1.701LysHis: 1.701 ± 0.753
0.85LysIle: 0.85 ± 0.377
4.252LysLys: 4.252 ± 0.59
5.952LysLeu: 5.952 ± 0.05
0.85LysMet: 0.85 ± 0.377
1.701LysAsn: 1.701 ± 0.753
0.85LysPro: 0.85 ± 0.377
0.85LysGln: 0.85 ± 0.916
1.701LysArg: 1.701 ± 0.753
1.701LysSer: 1.701 ± 0.753
0.85LysThr: 0.85 ± 0.916
3.401LysVal: 3.401 ± 1.506
0.0LysTrp: 0.0 ± 0.0
1.701LysTyr: 1.701 ± 0.753
0.0LysXaa: 0.0 ± 0.0
Leu
9.354LeuAla: 9.354 ± 0.263
2.551LeuCys: 2.551 ± 1.13
2.551LeuAsp: 2.551 ± 1.13
5.952LeuGlu: 5.952 ± 0.05
1.701LeuPhe: 1.701 ± 0.753
10.204LeuGly: 10.204 ± 1.933
0.85LeuHis: 0.85 ± 0.377
2.551LeuIle: 2.551 ± 1.13
0.85LeuLys: 0.85 ± 0.377
11.905LeuLeu: 11.905 ± 2.686
5.102LeuMet: 5.102 ± 0.345
3.401LeuAsn: 3.401 ± 0.213
7.653LeuPro: 7.653 ± 2.096
3.401LeuGln: 3.401 ± 1.08
8.503LeuArg: 8.503 ± 2.472
5.952LeuSer: 5.952 ± 1.343
5.102LeuThr: 5.102 ± 2.259
5.952LeuVal: 5.952 ± 1.243
1.701LeuTrp: 1.701 ± 0.54
1.701LeuTyr: 1.701 ± 0.753
0.0LeuXaa: 0.0 ± 0.0
Met
2.551MetAla: 2.551 ± 0.163
0.85MetCys: 0.85 ± 0.916
2.551MetAsp: 2.551 ± 0.163
1.701MetGlu: 1.701 ± 0.753
0.85MetPhe: 0.85 ± 0.916
0.85MetGly: 0.85 ± 0.377
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.85MetLys: 0.85 ± 0.377
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.701MetAsn: 1.701 ± 1.833
2.551MetPro: 2.551 ± 1.13
0.0MetGln: 0.0 ± 0.0
0.85MetArg: 0.85 ± 0.916
2.551MetSer: 2.551 ± 0.163
0.85MetThr: 0.85 ± 0.916
0.85MetVal: 0.85 ± 0.916
0.85MetTrp: 0.85 ± 0.377
0.85MetTyr: 0.85 ± 0.377
0.0MetXaa: 0.0 ± 0.0
Asn
1.701AsnAla: 1.701 ± 0.54
0.85AsnCys: 0.85 ± 0.377
2.551AsnAsp: 2.551 ± 0.163
3.401AsnGlu: 3.401 ± 1.506
0.85AsnPhe: 0.85 ± 0.377
5.102AsnGly: 5.102 ± 1.619
0.85AsnHis: 0.85 ± 0.377
0.0AsnIle: 0.0 ± 0.0
2.551AsnLys: 2.551 ± 0.163
1.701AsnLeu: 1.701 ± 0.753
0.85AsnMet: 0.85 ± 0.916
3.401AsnAsn: 3.401 ± 2.372
6.803AsnPro: 6.803 ± 4.745
0.0AsnGln: 0.0 ± 0.0
2.551AsnArg: 2.551 ± 1.13
0.85AsnSer: 0.85 ± 0.377
0.85AsnThr: 0.85 ± 0.377
5.952AsnVal: 5.952 ± 1.243
0.0AsnTrp: 0.0 ± 0.0
1.701AsnTyr: 1.701 ± 0.753
0.0AsnXaa: 0.0 ± 0.0
Pro
6.803ProAla: 6.803 ± 0.866
0.0ProCys: 0.0 ± 0.0
3.401ProAsp: 3.401 ± 0.213
3.401ProGlu: 3.401 ± 1.506
3.401ProPhe: 3.401 ± 0.213
5.102ProGly: 5.102 ± 2.912
0.85ProHis: 0.85 ± 0.916
3.401ProIle: 3.401 ± 0.213
0.85ProLys: 0.85 ± 0.377
6.803ProLeu: 6.803 ± 1.719
4.252ProMet: 4.252 ± 3.289
0.85ProAsn: 0.85 ± 0.377
8.503ProPro: 8.503 ± 2.472
1.701ProGln: 1.701 ± 0.753
6.803ProArg: 6.803 ± 4.745
5.102ProSer: 5.102 ± 0.326
4.252ProThr: 4.252 ± 1.883
3.401ProVal: 3.401 ± 0.213
0.85ProTrp: 0.85 ± 0.916
0.85ProTyr: 0.85 ± 0.916
0.0ProXaa: 0.0 ± 0.0
Gln
1.701GlnAla: 1.701 ± 0.753
1.701GlnCys: 1.701 ± 0.753
0.85GlnAsp: 0.85 ± 0.377
0.0GlnGlu: 0.0 ± 0.0
1.701GlnPhe: 1.701 ± 0.54
4.252GlnGly: 4.252 ± 1.996
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.701GlnLys: 1.701 ± 0.753
1.701GlnLeu: 1.701 ± 0.753
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
0.85GlnPro: 0.85 ± 0.377
0.85GlnGln: 0.85 ± 0.377
1.701GlnArg: 1.701 ± 0.753
1.701GlnSer: 1.701 ± 0.54
3.401GlnThr: 3.401 ± 2.372
2.551GlnVal: 2.551 ± 1.456
0.85GlnTrp: 0.85 ± 0.377
1.701GlnTyr: 1.701 ± 0.753
0.0GlnXaa: 0.0 ± 0.0
Arg
5.102ArgAla: 5.102 ± 1.619
2.551ArgCys: 2.551 ± 0.163
2.551ArgAsp: 2.551 ± 1.13
4.252ArgGlu: 4.252 ± 1.883
4.252ArgPhe: 4.252 ± 0.703
5.102ArgGly: 5.102 ± 0.326
2.551ArgHis: 2.551 ± 1.13
1.701ArgIle: 1.701 ± 0.753
0.85ArgLys: 0.85 ± 0.377
5.102ArgLeu: 5.102 ± 2.259
3.401ArgMet: 3.401 ± 0.213
2.551ArgAsn: 2.551 ± 1.13
2.551ArgPro: 2.551 ± 1.456
0.85ArgGln: 0.85 ± 0.377
13.605ArgArg: 13.605 ± 1.733
4.252ArgSer: 4.252 ± 0.59
7.653ArgThr: 7.653 ± 0.49
8.503ArgVal: 8.503 ± 0.113
3.401ArgTrp: 3.401 ± 0.213
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.803SerAla: 6.803 ± 1.719
1.701SerCys: 1.701 ± 0.753
4.252SerAsp: 4.252 ± 0.59
5.952SerGlu: 5.952 ± 0.05
4.252SerPhe: 4.252 ± 0.59
5.102SerGly: 5.102 ± 0.326
0.85SerHis: 0.85 ± 0.377
3.401SerIle: 3.401 ± 0.213
2.551SerLys: 2.551 ± 0.163
7.653SerLeu: 7.653 ± 1.783
2.551SerMet: 2.551 ± 1.13
1.701SerAsn: 1.701 ± 1.833
5.102SerPro: 5.102 ± 1.619
0.85SerGln: 0.85 ± 0.377
6.803SerArg: 6.803 ± 0.427
5.952SerSer: 5.952 ± 1.243
1.701SerThr: 1.701 ± 0.54
5.952SerVal: 5.952 ± 1.343
0.85SerTrp: 0.85 ± 0.377
1.701SerTyr: 1.701 ± 0.753
0.0SerXaa: 0.0 ± 0.0
Thr
4.252ThrAla: 4.252 ± 0.59
0.0ThrCys: 0.0 ± 0.0
3.401ThrAsp: 3.401 ± 1.506
4.252ThrGlu: 4.252 ± 0.59
0.85ThrPhe: 0.85 ± 0.377
6.803ThrGly: 6.803 ± 0.866
1.701ThrHis: 1.701 ± 0.54
3.401ThrIle: 3.401 ± 1.08
0.0ThrLys: 0.0 ± 0.0
2.551ThrLeu: 2.551 ± 0.163
0.0ThrMet: 0.0 ± 0.0
0.85ThrAsn: 0.85 ± 0.377
5.952ThrPro: 5.952 ± 1.343
2.551ThrGln: 2.551 ± 1.456
2.551ThrArg: 2.551 ± 0.163
3.401ThrSer: 3.401 ± 1.08
8.503ThrThr: 8.503 ± 7.87
2.551ThrVal: 2.551 ± 1.456
3.401ThrTrp: 3.401 ± 1.08
2.551ThrTyr: 2.551 ± 1.13
0.0ThrXaa: 0.0 ± 0.0
Val
4.252ValAla: 4.252 ± 0.703
0.85ValCys: 0.85 ± 0.916
0.85ValAsp: 0.85 ± 0.377
4.252ValGlu: 4.252 ± 0.703
1.701ValPhe: 1.701 ± 0.753
7.653ValGly: 7.653 ± 1.783
2.551ValHis: 2.551 ± 0.163
0.85ValIle: 0.85 ± 0.916
3.401ValLys: 3.401 ± 1.506
3.401ValLeu: 3.401 ± 1.506
0.85ValMet: 0.85 ± 0.916
4.252ValAsn: 4.252 ± 0.703
4.252ValPro: 4.252 ± 1.996
1.701ValGln: 1.701 ± 0.54
4.252ValArg: 4.252 ± 0.59
6.803ValSer: 6.803 ± 0.427
7.653ValThr: 7.653 ± 3.075
5.102ValVal: 5.102 ± 4.205
1.701ValTrp: 1.701 ± 0.753
2.551ValTyr: 2.551 ± 1.456
0.0ValXaa: 0.0 ± 0.0
Trp
3.401TrpAla: 3.401 ± 1.08
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.85TrpGly: 0.85 ± 0.916
0.0TrpHis: 0.0 ± 0.0
0.85TrpIle: 0.85 ± 0.377
2.551TrpLys: 2.551 ± 1.13
1.701TrpLeu: 1.701 ± 0.753
0.0TrpMet: 0.0 ± 0.367
0.85TrpAsn: 0.85 ± 0.916
0.85TrpPro: 0.85 ± 0.377
1.701TrpGln: 1.701 ± 0.753
4.252TrpArg: 4.252 ± 0.59
2.551TrpSer: 2.551 ± 0.163
0.0TrpThr: 0.0 ± 0.0
1.701TrpVal: 1.701 ± 0.753
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.401TyrAla: 3.401 ± 0.213
0.85TyrCys: 0.85 ± 0.377
1.701TyrAsp: 1.701 ± 0.753
0.0TyrGlu: 0.0 ± 0.0
1.701TyrPhe: 1.701 ± 0.54
1.701TyrGly: 1.701 ± 0.753
0.85TyrHis: 0.85 ± 0.916
0.85TyrIle: 0.85 ± 0.377
0.85TyrLys: 0.85 ± 0.377
1.701TyrLeu: 1.701 ± 0.753
0.85TyrMet: 0.85 ± 0.916
2.551TyrAsn: 2.551 ± 0.163
0.85TyrPro: 0.85 ± 0.377
2.551TyrGln: 2.551 ± 0.163
2.551TyrArg: 2.551 ± 1.13
3.401TyrSer: 3.401 ± 1.506
1.701TyrThr: 1.701 ± 0.753
0.85TyrVal: 0.85 ± 0.916
1.701TyrTrp: 1.701 ± 0.753
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1177 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski