Amino acid dipepetide frequency for Panax ginseng flexivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.219AlaAla: 4.219 ± 2.649
1.758AlaCys: 1.758 ± 0.887
3.516AlaAsp: 3.516 ± 1.454
5.626AlaGlu: 5.626 ± 1.934
3.868AlaPhe: 3.868 ± 0.677
4.219AlaGly: 4.219 ± 0.957
1.758AlaHis: 1.758 ± 2.3
2.461AlaIle: 2.461 ± 0.569
3.868AlaLys: 3.868 ± 0.807
7.736AlaLeu: 7.736 ± 3.025
1.406AlaMet: 1.406 ± 0.709
2.813AlaAsn: 2.813 ± 3.334
2.11AlaPro: 2.11 ± 0.628
1.406AlaGln: 1.406 ± 0.709
3.516AlaArg: 3.516 ± 1.229
3.165AlaSer: 3.165 ± 2.139
1.055AlaThr: 1.055 ± 0.532
4.219AlaVal: 4.219 ± 1.733
0.0AlaTrp: 0.0 ± 0.0
1.055AlaTyr: 1.055 ± 0.547
0.0AlaXaa: 0.0 ± 0.0
Cys
2.461CysAla: 2.461 ± 1.018
0.0CysCys: 0.0 ± 0.0
1.758CysAsp: 1.758 ± 0.552
1.758CysGlu: 1.758 ± 0.658
2.461CysPhe: 2.461 ± 0.853
1.758CysGly: 1.758 ± 1.112
0.0CysHis: 0.0 ± 0.0
1.406CysIle: 1.406 ± 0.709
1.758CysLys: 1.758 ± 0.658
4.219CysLeu: 4.219 ± 2.128
1.055CysMet: 1.055 ± 1.073
0.0CysAsn: 0.0 ± 0.0
1.055CysPro: 1.055 ± 1.152
1.055CysGln: 1.055 ± 0.732
1.406CysArg: 1.406 ± 0.709
1.758CysSer: 1.758 ± 0.7
1.406CysThr: 1.406 ± 0.709
2.461CysVal: 2.461 ± 1.763
0.703CysTrp: 0.703 ± 0.355
0.703CysTyr: 0.703 ± 0.355
0.0CysXaa: 0.0 ± 0.0
Asp
1.758AspAla: 1.758 ± 0.887
1.406AspCys: 1.406 ± 0.617
3.165AspAsp: 3.165 ± 1.596
3.516AspGlu: 3.516 ± 0.93
4.219AspPhe: 4.219 ± 0.923
2.813AspGly: 2.813 ± 1.004
1.406AspHis: 1.406 ± 0.709
2.813AspIle: 2.813 ± 0.563
3.516AspLys: 3.516 ± 0.93
10.197AspLeu: 10.197 ± 2.165
1.406AspMet: 1.406 ± 0.52
2.813AspAsn: 2.813 ± 1.348
2.461AspPro: 2.461 ± 0.853
1.055AspGln: 1.055 ± 0.532
2.461AspArg: 2.461 ± 1.241
4.571AspSer: 4.571 ± 1.766
0.352AspThr: 0.352 ± 0.775
3.868AspVal: 3.868 ± 1.175
2.461AspTrp: 2.461 ± 1.018
1.758AspTyr: 1.758 ± 0.887
0.0AspXaa: 0.0 ± 0.0
Glu
3.868GluAla: 3.868 ± 1.2
1.055GluCys: 1.055 ± 0.625
5.626GluAsp: 5.626 ± 1.499
4.923GluGlu: 4.923 ± 0.805
2.461GluPhe: 2.461 ± 1.052
3.868GluGly: 3.868 ± 1.346
1.055GluHis: 1.055 ± 0.532
3.516GluIle: 3.516 ± 1.038
5.274GluLys: 5.274 ± 2.084
4.571GluLeu: 4.571 ± 2.138
2.461GluMet: 2.461 ± 0.87
3.868GluAsn: 3.868 ± 1.439
1.406GluPro: 1.406 ± 1.362
2.461GluGln: 2.461 ± 0.749
4.219GluArg: 4.219 ± 1.407
5.626GluSer: 5.626 ± 1.753
3.165GluThr: 3.165 ± 0.61
7.032GluVal: 7.032 ± 2.153
0.352GluTrp: 0.352 ± 0.177
1.055GluTyr: 1.055 ± 0.625
0.0GluXaa: 0.0 ± 0.0
Phe
2.813PheAla: 2.813 ± 0.886
1.406PheCys: 1.406 ± 0.52
4.571PheAsp: 4.571 ± 1.377
8.087PheGlu: 8.087 ± 2.227
2.813PhePhe: 2.813 ± 2.258
3.868PheGly: 3.868 ± 1.39
0.352PheHis: 0.352 ± 0.177
3.165PheIle: 3.165 ± 1.596
3.868PheLys: 3.868 ± 0.742
7.384PheLeu: 7.384 ± 3.067
1.406PheMet: 1.406 ± 0.709
3.868PheAsn: 3.868 ± 1.353
2.11PhePro: 2.11 ± 1.075
1.758PheGln: 1.758 ± 1.156
3.516PheArg: 3.516 ± 1.025
5.274PheSer: 5.274 ± 1.242
2.813PheThr: 2.813 ± 0.991
2.813PheVal: 2.813 ± 1.605
0.703PheTrp: 0.703 ± 0.355
1.758PheTyr: 1.758 ± 0.658
0.0PheXaa: 0.0 ± 0.0
Gly
1.758GlyAla: 1.758 ± 1.093
1.406GlyCys: 1.406 ± 0.694
3.165GlyAsp: 3.165 ± 1.335
4.571GlyGlu: 4.571 ± 0.743
5.626GlyPhe: 5.626 ± 1.344
4.219GlyGly: 4.219 ± 4.53
1.758GlyHis: 1.758 ± 0.887
2.461GlyIle: 2.461 ± 1.04
6.681GlyLys: 6.681 ± 2.89
4.571GlyLeu: 4.571 ± 0.964
1.055GlyMet: 1.055 ± 0.532
2.11GlyAsn: 2.11 ± 1.093
1.055GlyPro: 1.055 ± 2.498
2.11GlyGln: 2.11 ± 1.075
3.165GlyArg: 3.165 ± 1.119
7.736GlySer: 7.736 ± 1.259
1.758GlyThr: 1.758 ± 2.357
3.868GlyVal: 3.868 ± 1.174
1.055GlyTrp: 1.055 ± 0.532
0.703GlyTyr: 0.703 ± 0.355
0.0GlyXaa: 0.0 ± 0.0
His
1.055HisAla: 1.055 ± 0.532
1.055HisCys: 1.055 ± 0.625
1.055HisAsp: 1.055 ± 0.532
0.352HisGlu: 0.352 ± 0.177
2.813HisPhe: 2.813 ± 0.563
1.055HisGly: 1.055 ± 1.152
1.406HisHis: 1.406 ± 0.709
2.11HisIle: 2.11 ± 1.064
2.461HisLys: 2.461 ± 1.229
3.516HisLeu: 3.516 ± 1.281
0.703HisMet: 0.703 ± 0.355
0.703HisAsn: 0.703 ± 1.476
0.352HisPro: 0.352 ± 0.177
0.0HisGln: 0.0 ± 0.0
1.406HisArg: 1.406 ± 0.52
3.165HisSer: 3.165 ± 0.867
0.703HisThr: 0.703 ± 1.211
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.11HisTyr: 2.11 ± 1.064
0.0HisXaa: 0.0 ± 0.0
Ile
2.813IleAla: 2.813 ± 0.563
2.461IleCys: 2.461 ± 0.853
3.165IleAsp: 3.165 ± 1.127
3.516IleGlu: 3.516 ± 0.717
3.516IlePhe: 3.516 ± 1.191
2.461IleGly: 2.461 ± 2.284
2.11IleHis: 2.11 ± 1.075
1.055IleIle: 1.055 ± 1.305
3.868IleLys: 3.868 ± 1.053
5.977IleLeu: 5.977 ± 3.073
1.758IleMet: 1.758 ± 0.887
3.868IleAsn: 3.868 ± 1.377
1.758IlePro: 1.758 ± 0.726
0.703IleGln: 0.703 ± 0.355
3.868IleArg: 3.868 ± 1.607
5.274IleSer: 5.274 ± 2.026
1.758IleThr: 1.758 ± 0.887
2.813IleVal: 2.813 ± 2.237
0.703IleTrp: 0.703 ± 0.625
1.758IleTyr: 1.758 ± 1.112
0.0IleXaa: 0.0 ± 0.0
Lys
5.274LysAla: 5.274 ± 1.423
1.406LysCys: 1.406 ± 0.709
2.813LysAsp: 2.813 ± 1.01
5.626LysGlu: 5.626 ± 0.821
3.868LysPhe: 3.868 ± 1.353
3.868LysGly: 3.868 ± 1.053
0.703LysHis: 0.703 ± 1.142
3.165LysIle: 3.165 ± 1.128
4.923LysLys: 4.923 ± 2.983
7.736LysLeu: 7.736 ± 2.314
1.758LysMet: 1.758 ± 0.887
2.461LysAsn: 2.461 ± 2.264
3.165LysPro: 3.165 ± 1.074
1.055LysGln: 1.055 ± 0.547
5.626LysArg: 5.626 ± 0.908
6.681LysSer: 6.681 ± 1.477
4.571LysThr: 4.571 ± 1.096
4.571LysVal: 4.571 ± 1.572
0.0LysTrp: 0.0 ± 0.0
0.703LysTyr: 0.703 ± 1.549
0.0LysXaa: 0.0 ± 0.0
Leu
8.79LeuAla: 8.79 ± 1.269
3.165LeuCys: 3.165 ± 1.596
6.329LeuAsp: 6.329 ± 1.59
4.923LeuGlu: 4.923 ± 2.27
5.274LeuPhe: 5.274 ± 1.323
8.087LeuGly: 8.087 ± 1.889
3.516LeuHis: 3.516 ± 1.281
8.087LeuIle: 8.087 ± 4.933
8.439LeuLys: 8.439 ± 3.658
7.032LeuLeu: 7.032 ± 2.389
2.813LeuMet: 2.813 ± 1.04
7.032LeuAsn: 7.032 ± 1.738
3.868LeuPro: 3.868 ± 2.359
1.758LeuGln: 1.758 ± 1.606
5.626LeuArg: 5.626 ± 0.608
6.681LeuSer: 6.681 ± 2.027
4.219LeuThr: 4.219 ± 1.447
4.923LeuVal: 4.923 ± 2.865
0.352LeuTrp: 0.352 ± 0.913
2.813LeuTyr: 2.813 ± 0.984
0.0LeuXaa: 0.0 ± 0.0
Met
2.11MetAla: 2.11 ± 1.093
0.352MetCys: 0.352 ± 0.177
0.703MetAsp: 0.703 ± 0.355
3.165MetGlu: 3.165 ± 1.035
0.352MetPhe: 0.352 ± 0.177
1.055MetGly: 1.055 ± 0.532
0.703MetHis: 0.703 ± 0.355
0.703MetIle: 0.703 ± 0.355
0.703MetLys: 0.703 ± 0.355
2.813MetLeu: 2.813 ± 0.945
0.352MetMet: 0.352 ± 0.177
1.758MetAsn: 1.758 ± 0.658
1.406MetPro: 1.406 ± 0.709
0.703MetGln: 0.703 ± 0.625
1.758MetArg: 1.758 ± 0.887
1.758MetSer: 1.758 ± 1.191
0.703MetThr: 0.703 ± 0.355
0.352MetVal: 0.352 ± 0.177
0.0MetTrp: 0.0 ± 0.0
1.055MetTyr: 1.055 ± 0.547
0.0MetXaa: 0.0 ± 0.0
Asn
1.758AsnAla: 1.758 ± 1.161
2.813AsnCys: 2.813 ± 0.945
3.868AsnAsp: 3.868 ± 1.353
2.11AsnGlu: 2.11 ± 0.634
5.626AsnPhe: 5.626 ± 1.46
3.165AsnGly: 3.165 ± 1.596
1.758AsnHis: 1.758 ± 0.887
2.11AsnIle: 2.11 ± 1.075
2.461AsnLys: 2.461 ± 1.241
5.977AsnLeu: 5.977 ± 2.869
0.352AsnMet: 0.352 ± 0.565
1.758AsnAsn: 1.758 ± 1.447
1.758AsnPro: 1.758 ± 1.161
1.055AsnGln: 1.055 ± 0.532
2.813AsnArg: 2.813 ± 1.09
4.219AsnSer: 4.219 ± 1.337
0.703AsnThr: 0.703 ± 0.355
1.758AsnVal: 1.758 ± 1.465
0.703AsnTrp: 0.703 ± 0.625
1.406AsnTyr: 1.406 ± 1.118
0.0AsnXaa: 0.0 ± 0.0
Pro
2.11ProAla: 2.11 ± 1.636
2.11ProCys: 2.11 ± 1.075
3.165ProAsp: 3.165 ± 0.61
3.165ProGlu: 3.165 ± 1.64
2.461ProPhe: 2.461 ± 1.298
2.813ProGly: 2.813 ± 3.735
0.703ProHis: 0.703 ± 2.583
1.758ProIle: 1.758 ± 0.887
0.703ProLys: 0.703 ± 1.211
3.516ProLeu: 3.516 ± 2.067
0.352ProMet: 0.352 ± 0.177
1.758ProAsn: 1.758 ± 1.295
1.406ProPro: 1.406 ± 0.52
1.055ProGln: 1.055 ± 0.532
1.055ProArg: 1.055 ± 0.532
1.758ProSer: 1.758 ± 0.887
2.11ProThr: 2.11 ± 1.093
0.703ProVal: 0.703 ± 0.355
0.703ProTrp: 0.703 ± 0.355
0.703ProTyr: 0.703 ± 0.355
0.0ProXaa: 0.0 ± 0.0
Gln
0.703GlnAla: 0.703 ± 0.625
0.352GlnCys: 0.352 ± 0.177
2.11GlnAsp: 2.11 ± 1.442
1.055GlnGlu: 1.055 ± 0.532
1.406GlnPhe: 1.406 ± 0.709
1.406GlnGly: 1.406 ± 0.52
1.055GlnHis: 1.055 ± 0.547
0.703GlnIle: 0.703 ± 0.355
1.406GlnLys: 1.406 ± 0.694
3.868GlnLeu: 3.868 ± 0.819
0.352GlnMet: 0.352 ± 0.177
1.406GlnAsn: 1.406 ± 1.257
1.055GlnPro: 1.055 ± 1.152
1.055GlnGln: 1.055 ± 1.416
2.11GlnArg: 2.11 ± 1.093
2.11GlnSer: 2.11 ± 1.093
0.703GlnThr: 0.703 ± 0.355
0.703GlnVal: 0.703 ± 0.355
0.0GlnTrp: 0.0 ± 0.0
1.055GlnTyr: 1.055 ± 1.152
0.0GlnXaa: 0.0 ± 0.0
Arg
1.758ArgAla: 1.758 ± 0.552
2.11ArgCys: 2.11 ± 1.442
2.813ArgAsp: 2.813 ± 0.984
3.165ArgGlu: 3.165 ± 2.405
4.571ArgPhe: 4.571 ± 0.645
3.516ArgGly: 3.516 ± 1.477
2.461ArgHis: 2.461 ± 0.853
4.571ArgIle: 4.571 ± 2.311
4.571ArgLys: 4.571 ± 1.377
3.868ArgLeu: 3.868 ± 0.807
1.055ArgMet: 1.055 ± 0.827
2.813ArgAsn: 2.813 ± 1.01
1.758ArgPro: 1.758 ± 1.191
2.11ArgGln: 2.11 ± 1.104
3.516ArgArg: 3.516 ± 1.269
4.923ArgSer: 4.923 ± 1.37
0.703ArgThr: 0.703 ± 0.625
3.868ArgVal: 3.868 ± 1.175
0.703ArgTrp: 0.703 ± 0.355
3.516ArgTyr: 3.516 ± 1.281
0.0ArgXaa: 0.0 ± 0.0
Ser
4.571SerAla: 4.571 ± 2.98
2.461SerCys: 2.461 ± 1.241
4.571SerAsp: 4.571 ± 1.096
6.681SerGlu: 6.681 ± 2.433
4.571SerPhe: 4.571 ± 1.226
5.274SerGly: 5.274 ± 1.411
2.461SerHis: 2.461 ± 0.853
5.977SerIle: 5.977 ± 1.309
7.032SerLys: 7.032 ± 0.58
7.384SerLeu: 7.384 ± 1.123
1.406SerMet: 1.406 ± 0.709
2.461SerAsn: 2.461 ± 0.569
3.165SerPro: 3.165 ± 0.998
1.406SerGln: 1.406 ± 0.709
6.681SerArg: 6.681 ± 0.471
8.087SerSer: 8.087 ± 3.433
2.813SerThr: 2.813 ± 1.41
7.032SerVal: 7.032 ± 1.232
0.703SerTrp: 0.703 ± 0.355
1.758SerTyr: 1.758 ± 0.887
0.0SerXaa: 0.0 ± 0.0
Thr
2.813ThrAla: 2.813 ± 2.514
1.406ThrCys: 1.406 ± 1.608
0.703ThrAsp: 0.703 ± 0.355
1.758ThrGlu: 1.758 ± 0.658
4.923ThrPhe: 4.923 ± 1.933
3.516ThrGly: 3.516 ± 1.347
1.055ThrHis: 1.055 ± 0.532
0.703ThrIle: 0.703 ± 0.355
2.813ThrLys: 2.813 ± 1.004
2.11ThrLeu: 2.11 ± 0.634
1.406ThrMet: 1.406 ± 0.686
1.055ThrAsn: 1.055 ± 0.547
0.703ThrPro: 0.703 ± 0.625
0.352ThrGln: 0.352 ± 0.738
0.703ThrArg: 0.703 ± 0.681
2.461ThrSer: 2.461 ± 1.229
0.352ThrThr: 0.352 ± 0.738
2.461ThrVal: 2.461 ± 1.229
0.352ThrTrp: 0.352 ± 0.177
1.758ThrTyr: 1.758 ± 0.887
0.0ThrXaa: 0.0 ± 0.0
Val
5.626ValAla: 5.626 ± 2.281
1.055ValCys: 1.055 ± 0.532
2.461ValAsp: 2.461 ± 1.338
2.11ValGlu: 2.11 ± 0.634
1.758ValPhe: 1.758 ± 1.161
3.165ValGly: 3.165 ± 1.773
1.055ValHis: 1.055 ± 0.532
5.977ValIle: 5.977 ± 1.374
5.274ValLys: 5.274 ± 1.715
5.626ValLeu: 5.626 ± 1.222
0.703ValMet: 0.703 ± 0.625
1.406ValAsn: 1.406 ± 0.617
2.461ValPro: 2.461 ± 1.139
2.11ValGln: 2.11 ± 0.634
3.516ValArg: 3.516 ± 1.03
6.681ValSer: 6.681 ± 1.312
3.165ValThr: 3.165 ± 0.61
2.813ValVal: 2.813 ± 1.203
0.703ValTrp: 0.703 ± 0.355
1.406ValTyr: 1.406 ± 0.694
0.0ValXaa: 0.0 ± 0.0
Trp
1.055TrpAla: 1.055 ± 0.547
0.352TrpCys: 0.352 ± 0.177
0.352TrpAsp: 0.352 ± 0.177
0.0TrpGlu: 0.0 ± 0.0
1.055TrpPhe: 1.055 ± 0.532
0.352TrpGly: 0.352 ± 0.177
0.352TrpHis: 0.352 ± 0.177
0.352TrpIle: 0.352 ± 0.177
0.352TrpLys: 0.352 ± 0.177
1.758TrpLeu: 1.758 ± 0.7
0.0TrpMet: 0.0 ± 0.0
1.055TrpAsn: 1.055 ± 0.547
0.703TrpPro: 0.703 ± 0.355
0.0TrpGln: 0.0 ± 0.0
0.352TrpArg: 0.352 ± 0.177
1.055TrpSer: 1.055 ± 1.152
0.352TrpThr: 0.352 ± 0.775
1.406TrpVal: 1.406 ± 0.709
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.461TyrAla: 2.461 ± 1.04
1.055TyrCys: 1.055 ± 1.416
2.11TyrAsp: 2.11 ± 1.064
1.758TyrGlu: 1.758 ± 0.887
0.703TyrPhe: 0.703 ± 0.355
0.352TyrGly: 0.352 ± 0.177
0.352TyrHis: 0.352 ± 0.177
2.11TyrIle: 2.11 ± 1.25
0.0TyrLys: 0.0 ± 0.0
3.868TyrLeu: 3.868 ± 1.451
0.352TyrMet: 0.352 ± 0.177
3.516TyrAsn: 3.516 ± 1.281
0.352TyrPro: 0.352 ± 0.177
1.406TyrGln: 1.406 ± 1.118
1.055TyrArg: 1.055 ± 0.532
3.516TyrSer: 3.516 ± 1.281
0.0TyrThr: 0.0 ± 0.0
1.406TyrVal: 1.406 ± 0.709
0.703TyrTrp: 0.703 ± 0.355
0.352TyrTyr: 0.352 ± 0.738
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2845 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski