Amino acid dipepetide frequency for Phytophthora parasitica P1569

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.332AlaAla: 9.332 ± 0.048	1.282AlaCys: 1.282 ± 0.011	4.218AlaAsp: 4.218 ± 0.023	5.267AlaGlu: 5.267 ± 0.026	3.161AlaPhe: 3.161 ± 0.018	4.64AlaGly: 4.64 ± 0.025	1.7AlaHis: 1.7 ± 0.013	3.788AlaIle: 3.788 ± 0.02	4.579AlaLys: 4.579 ± 0.024	8.378AlaLeu: 8.378 ± 0.039	2.239AlaMet: 2.239 ± 0.016	3.011AlaAsn: 3.011 ± 0.017	4.003AlaPro: 4.003 ± 0.031	3.458AlaGln: 3.458 ± 0.022	4.908AlaArg: 4.908 ± 0.028	7.502AlaSer: 7.502 ± 0.037	5.653AlaThr: 5.653 ± 0.032	6.162AlaVal: 6.162 ± 0.029	0.891AlaTrp: 0.891 ± 0.009	1.88AlaTyr: 1.88 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	1.265CysAla: 1.265 ± 0.012	0.451CysCys: 0.451 ± 0.007	0.857CysAsp: 0.857 ± 0.009	0.937CysGlu: 0.937 ± 0.009	0.703CysPhe: 0.703 ± 0.009	1.226CysGly: 1.226 ± 0.012	0.396CysHis: 0.396 ± 0.006	0.804CysIle: 0.804 ± 0.01	0.724CysLys: 0.724 ± 0.01	1.414CysLeu: 1.414 ± 0.012	0.406CysMet: 0.406 ± 0.006	0.55CysAsn: 0.55 ± 0.008	0.765CysPro: 0.765 ± 0.017	0.57CysGln: 0.57 ± 0.007	1.036CysArg: 1.036 ± 0.011	1.482CysSer: 1.482 ± 0.016	0.984CysThr: 0.984 ± 0.013	1.269CysVal: 1.269 ± 0.012	0.241CysTrp: 0.241 ± 0.005	0.472CysTyr: 0.472 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.105AspAla: 5.105 ± 0.025	0.817AspCys: 0.817 ± 0.009	4.393AspAsp: 4.393 ± 0.028	4.93AspGlu: 4.93 ± 0.028	2.16AspPhe: 2.16 ± 0.015	3.834AspGly: 3.834 ± 0.023	1.136AspHis: 1.136 ± 0.009	2.576AspIle: 2.576 ± 0.017	2.547AspLys: 2.547 ± 0.018	4.758AspLeu: 4.758 ± 0.023	1.304AspMet: 1.304 ± 0.011	2.004AspAsn: 2.004 ± 0.015	2.533AspPro: 2.533 ± 0.017	1.917AspGln: 1.917 ± 0.013	2.833AspArg: 2.833 ± 0.019	4.315AspSer: 4.315 ± 0.026	3.114AspThr: 3.114 ± 0.017	4.34AspVal: 4.34 ± 0.026	0.635AspTrp: 0.635 ± 0.008	1.444AspTyr: 1.444 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	5.765GluAla: 5.765 ± 0.033	0.933GluCys: 0.933 ± 0.01	4.338GluAsp: 4.338 ± 0.023	6.092GluGlu: 6.092 ± 0.037	2.266GluPhe: 2.266 ± 0.016	3.211GluGly: 3.211 ± 0.017	1.511GluHis: 1.511 ± 0.014	3.055GluIle: 3.055 ± 0.019	3.981GluLys: 3.981 ± 0.026	6.731GluLeu: 6.731 ± 0.033	1.825GluMet: 1.825 ± 0.014	2.632GluAsn: 2.632 ± 0.016	2.29GluPro: 2.29 ± 0.018	3.03GluGln: 3.03 ± 0.02	4.293GluArg: 4.293 ± 0.027	4.544GluSer: 4.544 ± 0.026	3.664GluThr: 3.664 ± 0.022	4.142GluVal: 4.142 ± 0.019	0.762GluTrp: 0.762 ± 0.009	1.689GluTyr: 1.689 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.052PheAla: 3.052 ± 0.017	0.734PheCys: 0.734 ± 0.01	2.272PheAsp: 2.272 ± 0.015	2.278PheGlu: 2.278 ± 0.015	1.647PhePhe: 1.647 ± 0.015	2.681PheGly: 2.681 ± 0.022	0.95PheHis: 0.95 ± 0.01	1.578PheIle: 1.578 ± 0.013	1.544PheLys: 1.544 ± 0.013	3.528PheLeu: 3.528 ± 0.025	0.936PheMet: 0.936 ± 0.011	1.335PheAsn: 1.335 ± 0.011	1.636PhePro: 1.636 ± 0.014	1.519PheGln: 1.519 ± 0.013	2.134PheArg: 2.134 ± 0.015	3.015PheSer: 3.015 ± 0.021	2.119PheThr: 2.119 ± 0.016	2.895PheVal: 2.895 ± 0.02	0.462PheTrp: 0.462 ± 0.007	1.176PheTyr: 1.176 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	4.744GlyAla: 4.744 ± 0.027	1.063GlyCys: 1.063 ± 0.012	3.687GlyAsp: 3.687 ± 0.023	3.505GlyGlu: 3.505 ± 0.019	2.351GlyPhe: 2.351 ± 0.017	4.624GlyGly: 4.624 ± 0.039	1.427GlyHis: 1.427 ± 0.014	2.775GlyIle: 2.775 ± 0.018	3.126GlyLys: 3.126 ± 0.018	4.733GlyLeu: 4.733 ± 0.024	1.441GlyMet: 1.441 ± 0.012	2.394GlyAsn: 2.394 ± 0.019	1.956GlyPro: 1.956 ± 0.015	1.939GlyGln: 1.939 ± 0.017	3.388GlyArg: 3.388 ± 0.023	5.308GlySer: 5.308 ± 0.036	3.303GlyThr: 3.303 ± 0.024	4.336GlyVal: 4.336 ± 0.02	0.757GlyTrp: 0.757 ± 0.009	1.787GlyTyr: 1.787 ± 0.016	0.0GlyXaa: 0.0 ± 0.0
His	1.828HisAla: 1.828 ± 0.014	0.447HisCys: 0.447 ± 0.006	1.291HisAsp: 1.291 ± 0.011	1.506HisGlu: 1.506 ± 0.013	1.01HisPhe: 1.01 ± 0.011	1.535HisGly: 1.535 ± 0.012	0.734HisHis: 0.734 ± 0.01	0.973HisIle: 0.973 ± 0.01	1.017HisLys: 1.017 ± 0.011	2.233HisLeu: 2.233 ± 0.015	0.496HisMet: 0.496 ± 0.006	0.772HisAsn: 0.772 ± 0.007	1.22HisPro: 1.22 ± 0.012	1.03HisGln: 1.03 ± 0.011	1.612HisArg: 1.612 ± 0.014	1.804HisSer: 1.804 ± 0.014	1.184HisThr: 1.184 ± 0.009	1.722HisVal: 1.722 ± 0.015	0.303HisTrp: 0.303 ± 0.005	0.686HisTyr: 0.686 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.831IleAla: 3.831 ± 0.018	0.838IleCys: 0.838 ± 0.01	2.553IleAsp: 2.553 ± 0.017	2.747IleGlu: 2.747 ± 0.018	1.659IlePhe: 1.659 ± 0.015	2.5IleGly: 2.5 ± 0.018	0.989IleHis: 0.989 ± 0.01	1.815IleIle: 1.815 ± 0.017	2.045IleLys: 2.045 ± 0.015	3.792IleLeu: 3.792 ± 0.026	0.968IleMet: 0.968 ± 0.01	1.521IleAsn: 1.521 ± 0.012	2.221IlePro: 2.221 ± 0.015	1.824IleGln: 1.824 ± 0.015	2.586IleArg: 2.586 ± 0.015	3.391IleSer: 3.391 ± 0.02	2.473IleThr: 2.473 ± 0.018	3.243IleVal: 3.243 ± 0.024	0.504IleTrp: 0.504 ± 0.007	1.144IleTyr: 1.144 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	4.089LysAla: 4.089 ± 0.025	0.782LysCys: 0.782 ± 0.009	2.531LysAsp: 2.531 ± 0.015	3.574LysGlu: 3.574 ± 0.022	1.681LysPhe: 1.681 ± 0.013	2.319LysGly: 2.319 ± 0.017	1.259LysHis: 1.259 ± 0.012	2.2LysIle: 2.2 ± 0.014	4.112LysLys: 4.112 ± 0.035	5.188LysLeu: 5.188 ± 0.029	1.404LysMet: 1.404 ± 0.012	2.007LysAsn: 2.007 ± 0.014	2.319LysPro: 2.319 ± 0.019	2.467LysGln: 2.467 ± 0.019	3.997LysArg: 3.997 ± 0.026	3.64LysSer: 3.64 ± 0.021	3.283LysThr: 3.283 ± 0.02	3.021LysVal: 3.021 ± 0.019	0.727LysTrp: 0.727 ± 0.009	1.5LysTyr: 1.5 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	7.913LeuAla: 7.913 ± 0.039	1.609LeuCys: 1.609 ± 0.015	5.12LeuAsp: 5.12 ± 0.024	6.508LeuGlu: 6.508 ± 0.036	3.477LeuPhe: 3.477 ± 0.023	4.879LeuGly: 4.879 ± 0.021	2.584LeuHis: 2.584 ± 0.017	3.343LeuIle: 3.343 ± 0.021	4.817LeuLys: 4.817 ± 0.027	10.018LeuLeu: 10.018 ± 0.052	2.183LeuMet: 2.183 ± 0.015	3.256LeuAsn: 3.256 ± 0.02	4.601LeuPro: 4.601 ± 0.023	4.914LeuGln: 4.914 ± 0.031	6.484LeuArg: 6.484 ± 0.032	7.4LeuSer: 7.4 ± 0.036	5.015LeuThr: 5.015 ± 0.024	6.511LeuVal: 6.511 ± 0.027	1.064LeuTrp: 1.064 ± 0.01	2.307LeuTyr: 2.307 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	2.191MetAla: 2.191 ± 0.016	0.368MetCys: 0.368 ± 0.005	1.45MetAsp: 1.45 ± 0.013	1.84MetGlu: 1.84 ± 0.014	0.792MetPhe: 0.792 ± 0.01	1.321MetGly: 1.321 ± 0.013	0.574MetHis: 0.574 ± 0.007	0.971MetIle: 0.971 ± 0.01	1.409MetLys: 1.409 ± 0.012	2.468MetLeu: 2.468 ± 0.016	0.708MetMet: 0.708 ± 0.009	0.951MetAsn: 0.951 ± 0.009	1.088MetPro: 1.088 ± 0.011	1.152MetGln: 1.152 ± 0.012	1.5MetArg: 1.5 ± 0.012	1.843MetSer: 1.843 ± 0.011	1.494MetThr: 1.494 ± 0.012	1.533MetVal: 1.533 ± 0.013	0.299MetTrp: 0.299 ± 0.005	0.623MetTyr: 0.623 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.44AsnAla: 3.44 ± 0.02	0.635AsnCys: 0.635 ± 0.009	2.127AsnAsp: 2.127 ± 0.015	2.43AsnGlu: 2.43 ± 0.016	1.352AsnPhe: 1.352 ± 0.011	2.795AsnGly: 2.795 ± 0.02	0.793AsnHis: 0.793 ± 0.008	1.56AsnIle: 1.56 ± 0.012	1.694AsnLys: 1.694 ± 0.013	3.032AsnLeu: 3.032 ± 0.021	0.889AsnMet: 0.889 ± 0.009	1.473AsnAsn: 1.473 ± 0.013	1.8AsnPro: 1.8 ± 0.014	1.414AsnGln: 1.414 ± 0.012	2.005AsnArg: 2.005 ± 0.016	2.961AsnSer: 2.961 ± 0.019	2.143AsnThr: 2.143 ± 0.014	2.719AsnVal: 2.719 ± 0.017	0.446AsnTrp: 0.446 ± 0.007	1.003AsnTyr: 1.003 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	4.031ProAla: 4.031 ± 0.027	0.566ProCys: 0.566 ± 0.01	2.378ProAsp: 2.378 ± 0.016	2.969ProGlu: 2.969 ± 0.019	1.648ProPhe: 1.648 ± 0.015	2.482ProGly: 2.482 ± 0.017	1.029ProHis: 1.029 ± 0.011	1.825ProIle: 1.825 ± 0.014	2.238ProLys: 2.238 ± 0.019	3.991ProLeu: 3.991 ± 0.019	1.084ProMet: 1.084 ± 0.01	1.644ProAsn: 1.644 ± 0.013	3.271ProPro: 3.271 ± 0.035	1.821ProGln: 1.821 ± 0.013	2.827ProArg: 2.827 ± 0.022	4.547ProSer: 4.547 ± 0.026	3.433ProThr: 3.433 ± 0.026	3.414ProVal: 3.414 ± 0.024	0.488ProTrp: 0.488 ± 0.008	1.024ProTyr: 1.024 ± 0.011	0.0ProXaa: 0.0 ± 0.0
Gln	3.276GlnAla: 3.276 ± 0.02	0.636GlnCys: 0.636 ± 0.008	2.029GlnAsp: 2.029 ± 0.014	2.902GlnGlu: 2.902 ± 0.02	1.469GlnPhe: 1.469 ± 0.011	1.839GlnGly: 1.839 ± 0.014	1.217GlnHis: 1.217 ± 0.012	1.81GlnIle: 1.81 ± 0.014	2.175GlnLys: 2.175 ± 0.016	4.672GlnLeu: 4.672 ± 0.028	1.082GlnMet: 1.082 ± 0.011	1.467GlnAsn: 1.467 ± 0.013	1.836GlnPro: 1.836 ± 0.014	3.1GlnGln: 3.1 ± 0.032	3.318GlnArg: 3.318 ± 0.023	2.98GlnSer: 2.98 ± 0.02	2.363GlnThr: 2.363 ± 0.016	2.724GlnVal: 2.724 ± 0.016	0.593GlnTrp: 0.593 ± 0.008	1.123GlnTyr: 1.123 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	4.875ArgAla: 4.875 ± 0.025	1.07ArgCys: 1.07 ± 0.011	3.228ArgAsp: 3.228 ± 0.019	4.078ArgGlu: 4.078 ± 0.024	2.393ArgPhe: 2.393 ± 0.015	3.506ArgGly: 3.506 ± 0.025	1.655ArgHis: 1.655 ± 0.014	2.674ArgIle: 2.674 ± 0.016	3.651ArgLys: 3.651 ± 0.022	5.956ArgLeu: 5.956 ± 0.031	1.513ArgMet: 1.513 ± 0.011	2.24ArgAsn: 2.24 ± 0.016	2.532ArgPro: 2.532 ± 0.018	2.994ArgGln: 2.994 ± 0.022	5.567ArgArg: 5.567 ± 0.039	5.235ArgSer: 5.235 ± 0.031	3.192ArgThr: 3.192 ± 0.02	4.343ArgVal: 4.343 ± 0.025	0.871ArgTrp: 0.871 ± 0.011	1.667ArgTyr: 1.667 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	6.793SerAla: 6.793 ± 0.032	1.305SerCys: 1.305 ± 0.013	4.743SerAsp: 4.743 ± 0.027	4.626SerGlu: 4.626 ± 0.027	3.126SerPhe: 3.126 ± 0.022	5.348SerGly: 5.348 ± 0.036	1.629SerHis: 1.629 ± 0.014	3.628SerIle: 3.628 ± 0.021	3.993SerLys: 3.993 ± 0.022	6.991SerLeu: 6.991 ± 0.032	1.952SerMet: 1.952 ± 0.016	3.165SerAsn: 3.165 ± 0.018	4.348SerPro: 4.348 ± 0.027	2.797SerGln: 2.797 ± 0.019	4.871SerArg: 4.871 ± 0.029	9.931SerSer: 9.931 ± 0.059	5.976SerThr: 5.976 ± 0.035	5.535SerVal: 5.535 ± 0.027	0.976SerTrp: 0.976 ± 0.01	1.949SerTyr: 1.949 ± 0.015	0.0SerXaa: 0.0 ± 0.0
Thr	5.308ThrAla: 5.308 ± 0.027	0.967ThrCys: 0.967 ± 0.011	2.954ThrAsp: 2.954 ± 0.017	3.494ThrGlu: 3.494 ± 0.021	2.132ThrPhe: 2.132 ± 0.017	3.656ThrGly: 3.656 ± 0.028	1.247ThrHis: 1.247 ± 0.011	2.685ThrIle: 2.685 ± 0.02	3.081ThrLys: 3.081 ± 0.02	5.475ThrLeu: 5.475 ± 0.025	1.405ThrMet: 1.405 ± 0.012	2.175ThrAsn: 2.175 ± 0.016	3.647ThrPro: 3.647 ± 0.027	2.347ThrGln: 2.347 ± 0.016	3.425ThrArg: 3.425 ± 0.021	5.597ThrSer: 5.597 ± 0.03	4.487ThrThr: 4.487 ± 0.033	3.891ThrVal: 3.891 ± 0.026	0.698ThrTrp: 0.698 ± 0.009	1.4ThrTyr: 1.4 ± 0.013	0.0ThrXaa: 0.0 ± 0.0
Val	6.407ValAla: 6.407 ± 0.029	1.272ValCys: 1.272 ± 0.012	4.3ValAsp: 4.3 ± 0.022	4.736ValGlu: 4.736 ± 0.023	2.801ValPhe: 2.801 ± 0.019	3.845ValGly: 3.845 ± 0.022	1.609ValHis: 1.609 ± 0.013	2.909ValIle: 2.909 ± 0.021	3.46ValLys: 3.46 ± 0.021	6.882ValLeu: 6.882 ± 0.03	1.679ValMet: 1.679 ± 0.013	2.547ValAsn: 2.547 ± 0.015	3.138ValPro: 3.138 ± 0.018	2.808ValGln: 2.808 ± 0.019	3.949ValArg: 3.949 ± 0.02	5.343ValSer: 5.343 ± 0.027	4.025ValThr: 4.025 ± 0.026	5.624ValVal: 5.624 ± 0.028	0.799ValTrp: 0.799 ± 0.011	1.878ValTyr: 1.878 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	0.723TrpAla: 0.723 ± 0.008	0.225TrpCys: 0.225 ± 0.005	0.663TrpAsp: 0.663 ± 0.009	0.687TrpGlu: 0.687 ± 0.007	0.476TrpPhe: 0.476 ± 0.008	0.66TrpGly: 0.66 ± 0.01	0.291TrpHis: 0.291 ± 0.005	0.611TrpIle: 0.611 ± 0.008	0.795TrpLys: 0.795 ± 0.009	1.245TrpLeu: 1.245 ± 0.016	0.408TrpMet: 0.408 ± 0.007	0.558TrpAsn: 0.558 ± 0.008	0.393TrpPro: 0.393 ± 0.006	0.491TrpGln: 0.491 ± 0.007	0.876TrpArg: 0.876 ± 0.011	0.926TrpSer: 0.926 ± 0.011	0.756TrpThr: 0.756 ± 0.01	0.722TrpVal: 0.722 ± 0.008	0.191TrpTrp: 0.191 ± 0.004	0.368TrpTyr: 0.368 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.086TyrAla: 2.086 ± 0.012	0.551TyrCys: 0.551 ± 0.01	1.56TyrAsp: 1.56 ± 0.015	1.648TyrGlu: 1.648 ± 0.011	1.187TyrPhe: 1.187 ± 0.012	1.743TyrGly: 1.743 ± 0.018	0.672TyrHis: 0.672 ± 0.009	1.065TyrIle: 1.065 ± 0.011	1.113TyrLys: 1.113 ± 0.012	2.517TyrLeu: 2.517 ± 0.018	0.654TyrMet: 0.654 ± 0.007	1.01TyrAsn: 1.01 ± 0.01	1.113TyrPro: 1.113 ± 0.012	1.017TyrGln: 1.017 ± 0.011	1.634TyrArg: 1.634 ± 0.012	1.916TyrSer: 1.916 ± 0.016	1.408TyrThr: 1.408 ± 0.012	1.866TyrVal: 1.866 ± 0.016	0.36TyrTrp: 0.36 ± 0.005	0.87TyrTyr: 0.87 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 26477 proteins (10979262 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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