Amino acid dipepetide frequency for Hubei picorna-like virus 30

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.671AlaAla: 7.671 ± 0.0
0.0AlaCys: 0.0 ± 0.0
3.288AlaAsp: 3.288 ± 0.0
1.644AlaGlu: 1.644 ± 0.0
2.192AlaPhe: 2.192 ± 0.0
4.932AlaGly: 4.932 ± 0.0
1.644AlaHis: 1.644 ± 0.0
2.192AlaIle: 2.192 ± 0.0
4.932AlaLys: 4.932 ± 0.0
1.644AlaLeu: 1.644 ± 0.0
3.288AlaMet: 3.288 ± 0.0
3.288AlaAsn: 3.288 ± 0.0
4.932AlaPro: 4.932 ± 0.0
2.74AlaGln: 2.74 ± 0.0
3.836AlaArg: 3.836 ± 0.0
3.836AlaSer: 3.836 ± 0.0
3.836AlaThr: 3.836 ± 0.0
4.384AlaVal: 4.384 ± 0.0
0.548AlaTrp: 0.548 ± 0.0
3.288AlaTyr: 3.288 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.096CysAla: 1.096 ± 0.0
1.096CysCys: 1.096 ± 0.0
1.096CysAsp: 1.096 ± 0.0
0.548CysGlu: 0.548 ± 0.0
0.548CysPhe: 0.548 ± 0.0
1.644CysGly: 1.644 ± 0.0
0.548CysHis: 0.548 ± 0.0
0.548CysIle: 0.548 ± 0.0
0.548CysLys: 0.548 ± 0.0
2.192CysLeu: 2.192 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.192CysArg: 2.192 ± 0.0
2.192CysSer: 2.192 ± 0.0
2.192CysThr: 2.192 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.74AspAla: 2.74 ± 0.0
0.548AspCys: 0.548 ± 0.0
2.74AspAsp: 2.74 ± 0.0
3.836AspGlu: 3.836 ± 0.0
3.288AspPhe: 3.288 ± 0.0
2.74AspGly: 2.74 ± 0.0
0.548AspHis: 0.548 ± 0.0
7.671AspIle: 7.671 ± 0.0
4.932AspLys: 4.932 ± 0.0
2.74AspLeu: 2.74 ± 0.0
1.644AspMet: 1.644 ± 0.0
3.836AspAsn: 3.836 ± 0.0
3.288AspPro: 3.288 ± 0.0
1.096AspGln: 1.096 ± 0.0
1.644AspArg: 1.644 ± 0.0
4.384AspSer: 4.384 ± 0.0
2.192AspThr: 2.192 ± 0.0
3.836AspVal: 3.836 ± 0.0
1.096AspTrp: 1.096 ± 0.0
2.192AspTyr: 2.192 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.288GluAla: 3.288 ± 0.0
1.096GluCys: 1.096 ± 0.0
4.932GluAsp: 4.932 ± 0.0
4.384GluGlu: 4.384 ± 0.0
1.644GluPhe: 1.644 ± 0.0
6.027GluGly: 6.027 ± 0.0
0.0GluHis: 0.0 ± 0.0
3.288GluIle: 3.288 ± 0.0
3.836GluLys: 3.836 ± 0.0
6.027GluLeu: 6.027 ± 0.0
3.288GluMet: 3.288 ± 0.0
2.192GluAsn: 2.192 ± 0.0
2.74GluPro: 2.74 ± 0.0
1.644GluGln: 1.644 ± 0.0
2.74GluArg: 2.74 ± 0.0
2.192GluSer: 2.192 ± 0.0
3.288GluThr: 3.288 ± 0.0
3.288GluVal: 3.288 ± 0.0
2.192GluTrp: 2.192 ± 0.0
4.384GluTyr: 4.384 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.548PheCys: 0.548 ± 0.0
4.932PheAsp: 4.932 ± 0.0
4.384PheGlu: 4.384 ± 0.0
1.644PhePhe: 1.644 ± 0.0
3.288PheGly: 3.288 ± 0.0
0.548PheHis: 0.548 ± 0.0
3.288PheIle: 3.288 ± 0.0
3.836PheLys: 3.836 ± 0.0
3.836PheLeu: 3.836 ± 0.0
0.548PheMet: 0.548 ± 0.0
1.096PheAsn: 1.096 ± 0.0
2.192PhePro: 2.192 ± 0.0
1.644PheGln: 1.644 ± 0.0
1.644PheArg: 1.644 ± 0.0
3.836PheSer: 3.836 ± 0.0
2.74PheThr: 2.74 ± 0.0
3.836PheVal: 3.836 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.644GlyAla: 1.644 ± 0.0
1.096GlyCys: 1.096 ± 0.0
2.74GlyAsp: 2.74 ± 0.0
6.027GlyGlu: 6.027 ± 0.0
4.384GlyPhe: 4.384 ± 0.0
1.644GlyGly: 1.644 ± 0.0
0.548GlyHis: 0.548 ± 0.0
2.74GlyIle: 2.74 ± 0.0
7.671GlyLys: 7.671 ± 0.0
8.219GlyLeu: 8.219 ± 0.0
1.096GlyMet: 1.096 ± 0.0
1.644GlyAsn: 1.644 ± 0.0
2.74GlyPro: 2.74 ± 0.0
2.192GlyGln: 2.192 ± 0.0
2.192GlyArg: 2.192 ± 0.0
2.74GlySer: 2.74 ± 0.0
4.932GlyThr: 4.932 ± 0.0
4.384GlyVal: 4.384 ± 0.0
0.548GlyTrp: 0.548 ± 0.0
3.288GlyTyr: 3.288 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.096HisAla: 1.096 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.096HisAsp: 1.096 ± 0.0
0.548HisGlu: 0.548 ± 0.0
1.096HisPhe: 1.096 ± 0.0
0.548HisGly: 0.548 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.548HisIle: 0.548 ± 0.0
0.548HisLys: 0.548 ± 0.0
1.096HisLeu: 1.096 ± 0.0
0.548HisMet: 0.548 ± 0.0
1.644HisAsn: 1.644 ± 0.0
2.192HisPro: 2.192 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.548HisArg: 0.548 ± 0.0
1.096HisSer: 1.096 ± 0.0
1.644HisThr: 1.644 ± 0.0
1.096HisVal: 1.096 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.096HisTyr: 1.096 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.836IleAla: 3.836 ± 0.0
0.548IleCys: 0.548 ± 0.0
2.192IleAsp: 2.192 ± 0.0
6.027IleGlu: 6.027 ± 0.0
1.644IlePhe: 1.644 ± 0.0
1.096IleGly: 1.096 ± 0.0
2.192IleHis: 2.192 ± 0.0
1.644IleIle: 1.644 ± 0.0
5.479IleLys: 5.479 ± 0.0
3.836IleLeu: 3.836 ± 0.0
0.548IleMet: 0.548 ± 0.0
3.836IleAsn: 3.836 ± 0.0
3.836IlePro: 3.836 ± 0.0
2.192IleGln: 2.192 ± 0.0
2.74IleArg: 2.74 ± 0.0
4.384IleSer: 4.384 ± 0.0
3.288IleThr: 3.288 ± 0.0
2.192IleVal: 2.192 ± 0.0
2.192IleTrp: 2.192 ± 0.0
1.644IleTyr: 1.644 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.836LysAla: 3.836 ± 0.0
0.548LysCys: 0.548 ± 0.0
5.479LysAsp: 5.479 ± 0.0
4.384LysGlu: 4.384 ± 0.0
1.096LysPhe: 1.096 ± 0.0
6.027LysGly: 6.027 ± 0.0
1.096LysHis: 1.096 ± 0.0
3.288LysIle: 3.288 ± 0.0
1.096LysLys: 1.096 ± 0.0
8.767LysLeu: 8.767 ± 0.0
2.74LysMet: 2.74 ± 0.0
0.0LysAsn: 0.0 ± 0.0
1.644LysPro: 1.644 ± 0.0
1.644LysGln: 1.644 ± 0.0
5.479LysArg: 5.479 ± 0.0
6.575LysSer: 6.575 ± 0.0
5.479LysThr: 5.479 ± 0.0
4.932LysVal: 4.932 ± 0.0
1.644LysTrp: 1.644 ± 0.0
3.288LysTyr: 3.288 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.479LeuAla: 5.479 ± 0.0
1.096LeuCys: 1.096 ± 0.0
4.932LeuAsp: 4.932 ± 0.0
6.575LeuGlu: 6.575 ± 0.0
6.027LeuPhe: 6.027 ± 0.0
2.74LeuGly: 2.74 ± 0.0
0.548LeuHis: 0.548 ± 0.0
6.027LeuIle: 6.027 ± 0.0
6.575LeuLys: 6.575 ± 0.0
9.315LeuLeu: 9.315 ± 0.0
3.288LeuMet: 3.288 ± 0.0
4.384LeuAsn: 4.384 ± 0.0
0.548LeuPro: 0.548 ± 0.0
4.384LeuGln: 4.384 ± 0.0
4.384LeuArg: 4.384 ± 0.0
7.123LeuSer: 7.123 ± 0.0
4.384LeuThr: 4.384 ± 0.0
8.767LeuVal: 8.767 ± 0.0
1.096LeuTrp: 1.096 ± 0.0
4.384LeuTyr: 4.384 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.644MetAla: 1.644 ± 0.0
1.096MetCys: 1.096 ± 0.0
1.644MetAsp: 1.644 ± 0.0
2.192MetGlu: 2.192 ± 0.0
0.548MetPhe: 0.548 ± 0.0
1.644MetGly: 1.644 ± 0.0
0.548MetHis: 0.548 ± 0.0
1.644MetIle: 1.644 ± 0.0
4.384MetLys: 4.384 ± 0.0
0.548MetLeu: 0.548 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.096MetAsn: 1.096 ± 0.0
0.548MetPro: 0.548 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.548MetArg: 0.548 ± 0.0
5.479MetSer: 5.479 ± 0.0
1.096MetThr: 1.096 ± 0.0
1.096MetVal: 1.096 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.548MetTyr: 0.548 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.74AsnAla: 2.74 ± 0.0
0.0AsnCys: 0.0 ± 0.0
2.192AsnAsp: 2.192 ± 0.0
2.74AsnGlu: 2.74 ± 0.0
0.548AsnPhe: 0.548 ± 0.0
2.192AsnGly: 2.192 ± 0.0
0.548AsnHis: 0.548 ± 0.0
2.192AsnIle: 2.192 ± 0.0
1.644AsnLys: 1.644 ± 0.0
3.836AsnLeu: 3.836 ± 0.0
1.096AsnMet: 1.096 ± 0.0
2.192AsnAsn: 2.192 ± 0.0
4.384AsnPro: 4.384 ± 0.0
0.548AsnGln: 0.548 ± 0.0
2.192AsnArg: 2.192 ± 0.0
3.288AsnSer: 3.288 ± 0.0
2.192AsnThr: 2.192 ± 0.0
3.836AsnVal: 3.836 ± 0.0
0.548AsnTrp: 0.548 ± 0.0
0.548AsnTyr: 0.548 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.74ProAla: 2.74 ± 0.0
1.096ProCys: 1.096 ± 0.0
2.74ProAsp: 2.74 ± 0.0
1.644ProGlu: 1.644 ± 0.0
1.096ProPhe: 1.096 ± 0.0
3.288ProGly: 3.288 ± 0.0
1.644ProHis: 1.644 ± 0.0
2.74ProIle: 2.74 ± 0.0
2.74ProLys: 2.74 ± 0.0
4.384ProLeu: 4.384 ± 0.0
0.0ProMet: 0.0 ± 0.0
1.644ProAsn: 1.644 ± 0.0
2.74ProPro: 2.74 ± 0.0
3.836ProGln: 3.836 ± 0.0
2.192ProArg: 2.192 ± 0.0
2.74ProSer: 2.74 ± 0.0
2.74ProThr: 2.74 ± 0.0
3.836ProVal: 3.836 ± 0.0
1.096ProTrp: 1.096 ± 0.0
2.74ProTyr: 2.74 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.644GlnAla: 1.644 ± 0.0
0.0GlnCys: 0.0 ± 0.0
2.192GlnAsp: 2.192 ± 0.0
1.096GlnGlu: 1.096 ± 0.0
1.096GlnPhe: 1.096 ± 0.0
5.479GlnGly: 5.479 ± 0.0
0.0GlnHis: 0.0 ± 0.0
1.644GlnIle: 1.644 ± 0.0
2.74GlnLys: 2.74 ± 0.0
3.836GlnLeu: 3.836 ± 0.0
1.096GlnMet: 1.096 ± 0.0
1.096GlnAsn: 1.096 ± 0.0
1.096GlnPro: 1.096 ± 0.0
1.644GlnGln: 1.644 ± 0.0
1.096GlnArg: 1.096 ± 0.0
3.288GlnSer: 3.288 ± 0.0
0.548GlnThr: 0.548 ± 0.0
2.192GlnVal: 2.192 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.644GlnTyr: 1.644 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.192ArgAla: 2.192 ± 0.0
2.74ArgCys: 2.74 ± 0.0
3.836ArgAsp: 3.836 ± 0.0
2.192ArgGlu: 2.192 ± 0.0
3.836ArgPhe: 3.836 ± 0.0
2.74ArgGly: 2.74 ± 0.0
1.644ArgHis: 1.644 ± 0.0
1.096ArgIle: 1.096 ± 0.0
1.644ArgLys: 1.644 ± 0.0
5.479ArgLeu: 5.479 ± 0.0
1.644ArgMet: 1.644 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
1.644ArgPro: 1.644 ± 0.0
2.192ArgGln: 2.192 ± 0.0
1.096ArgArg: 1.096 ± 0.0
3.288ArgSer: 3.288 ± 0.0
3.288ArgThr: 3.288 ± 0.0
3.288ArgVal: 3.288 ± 0.0
0.548ArgTrp: 0.548 ± 0.0
1.644ArgTyr: 1.644 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
2.192SerAla: 2.192 ± 0.0
1.096SerCys: 1.096 ± 0.0
4.932SerAsp: 4.932 ± 0.0
4.384SerGlu: 4.384 ± 0.0
5.479SerPhe: 5.479 ± 0.0
5.479SerGly: 5.479 ± 0.0
1.096SerHis: 1.096 ± 0.0
4.932SerIle: 4.932 ± 0.0
6.027SerLys: 6.027 ± 0.0
7.123SerLeu: 7.123 ± 0.0
2.74SerMet: 2.74 ± 0.0
2.192SerAsn: 2.192 ± 0.0
4.384SerPro: 4.384 ± 0.0
2.74SerGln: 2.74 ± 0.0
1.096SerArg: 1.096 ± 0.0
7.123SerSer: 7.123 ± 0.0
6.575SerThr: 6.575 ± 0.0
4.932SerVal: 4.932 ± 0.0
2.192SerTrp: 2.192 ± 0.0
3.288SerTyr: 3.288 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
7.671ThrAla: 7.671 ± 0.0
1.096ThrCys: 1.096 ± 0.0
1.644ThrAsp: 1.644 ± 0.0
2.192ThrGlu: 2.192 ± 0.0
2.192ThrPhe: 2.192 ± 0.0
2.192ThrGly: 2.192 ± 0.0
0.0ThrHis: 0.0 ± 0.0
2.192ThrIle: 2.192 ± 0.0
2.74ThrLys: 2.74 ± 0.0
7.123ThrLeu: 7.123 ± 0.0
0.548ThrMet: 0.548 ± 0.0
1.644ThrAsn: 1.644 ± 0.0
4.932ThrPro: 4.932 ± 0.0
0.548ThrGln: 0.548 ± 0.0
4.384ThrArg: 4.384 ± 0.0
6.575ThrSer: 6.575 ± 0.0
4.384ThrThr: 4.384 ± 0.0
6.027ThrVal: 6.027 ± 0.0
1.644ThrTrp: 1.644 ± 0.0
1.096ThrTyr: 1.096 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
9.315ValAla: 9.315 ± 0.0
1.096ValCys: 1.096 ± 0.0
2.192ValAsp: 2.192 ± 0.0
4.384ValGlu: 4.384 ± 0.0
3.288ValPhe: 3.288 ± 0.0
3.836ValGly: 3.836 ± 0.0
2.192ValHis: 2.192 ± 0.0
4.384ValIle: 4.384 ± 0.0
5.479ValLys: 5.479 ± 0.0
4.932ValLeu: 4.932 ± 0.0
0.548ValMet: 0.548 ± 0.0
4.384ValAsn: 4.384 ± 0.0
2.192ValPro: 2.192 ± 0.0
3.288ValGln: 3.288 ± 0.0
4.932ValArg: 4.932 ± 0.0
2.74ValSer: 2.74 ± 0.0
3.288ValThr: 3.288 ± 0.0
4.932ValVal: 4.932 ± 0.0
1.096ValTrp: 1.096 ± 0.0
1.644ValTyr: 1.644 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.548TrpAla: 0.548 ± 0.0
0.548TrpCys: 0.548 ± 0.0
0.548TrpAsp: 0.548 ± 0.0
1.096TrpGlu: 1.096 ± 0.0
0.548TrpPhe: 0.548 ± 0.0
1.096TrpGly: 1.096 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.548TrpIle: 0.548 ± 0.0
0.548TrpLys: 0.548 ± 0.0
4.384TrpLeu: 4.384 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.548TrpPro: 0.548 ± 0.0
0.548TrpGln: 0.548 ± 0.0
0.548TrpArg: 0.548 ± 0.0
1.644TrpSer: 1.644 ± 0.0
0.548TrpThr: 0.548 ± 0.0
1.644TrpVal: 1.644 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.096TrpTyr: 1.096 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.74TyrAla: 2.74 ± 0.0
1.096TyrCys: 1.096 ± 0.0
1.644TyrAsp: 1.644 ± 0.0
2.192TyrGlu: 2.192 ± 0.0
1.644TyrPhe: 1.644 ± 0.0
3.836TyrGly: 3.836 ± 0.0
1.096TyrHis: 1.096 ± 0.0
2.74TyrIle: 2.74 ± 0.0
1.644TyrLys: 1.644 ± 0.0
2.74TyrLeu: 2.74 ± 0.0
1.096TyrMet: 1.096 ± 0.0
3.288TyrAsn: 3.288 ± 0.0
1.096TyrPro: 1.096 ± 0.0
1.096TyrGln: 1.096 ± 0.0
0.548TyrArg: 0.548 ± 0.0
5.479TyrSer: 5.479 ± 0.0
2.192TyrThr: 2.192 ± 0.0
1.644TyrVal: 1.644 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.74TyrTyr: 2.74 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (1826 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski