Amino acid dipepetide frequency for Parabacteroides chinchillae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.493AlaAla: 5.493 ± 0.115	0.931AlaCys: 0.931 ± 0.032	4.099AlaAsp: 4.099 ± 0.066	4.566AlaGlu: 4.566 ± 0.071	3.223AlaPhe: 3.223 ± 0.063	5.409AlaGly: 5.409 ± 0.085	1.096AlaHis: 1.096 ± 0.03	5.133AlaIle: 5.133 ± 0.076	4.328AlaLys: 4.328 ± 0.067	6.61AlaLeu: 6.61 ± 0.092	1.862AlaMet: 1.862 ± 0.041	3.4AlaAsn: 3.4 ± 0.063	2.282AlaPro: 2.282 ± 0.047	2.433AlaGln: 2.433 ± 0.048	2.877AlaArg: 2.877 ± 0.057	4.394AlaSer: 4.394 ± 0.069	3.87AlaThr: 3.87 ± 0.07	4.707AlaVal: 4.707 ± 0.078	0.736AlaTrp: 0.736 ± 0.026	2.833AlaTyr: 2.833 ± 0.056	0.0AlaXaa: 0.0 ± 0.0
Cys	0.746CysAla: 0.746 ± 0.029	0.215CysCys: 0.215 ± 0.015	0.583CysAsp: 0.583 ± 0.021	0.584CysGlu: 0.584 ± 0.026	0.604CysPhe: 0.604 ± 0.022	0.995CysGly: 0.995 ± 0.037	0.27CysHis: 0.27 ± 0.017	0.967CysIle: 0.967 ± 0.029	0.797CysLys: 0.797 ± 0.026	1.079CysLeu: 1.079 ± 0.033	0.349CysMet: 0.349 ± 0.018	0.622CysAsn: 0.622 ± 0.024	0.553CysPro: 0.553 ± 0.024	0.31CysGln: 0.31 ± 0.017	0.549CysArg: 0.549 ± 0.024	0.791CysSer: 0.791 ± 0.029	0.645CysThr: 0.645 ± 0.023	0.678CysVal: 0.678 ± 0.028	0.153CysTrp: 0.153 ± 0.014	0.521CysTyr: 0.521 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.856AspAla: 3.856 ± 0.061	0.603AspCys: 0.603 ± 0.027	2.669AspAsp: 2.669 ± 0.06	3.727AspGlu: 3.727 ± 0.074	2.904AspPhe: 2.904 ± 0.055	3.861AspGly: 3.861 ± 0.061	0.822AspHis: 0.822 ± 0.031	4.596AspIle: 4.596 ± 0.069	4.198AspLys: 4.198 ± 0.065	4.708AspLeu: 4.708 ± 0.07	1.679AspMet: 1.679 ± 0.042	3.04AspAsn: 3.04 ± 0.054	1.946AspPro: 1.946 ± 0.041	1.362AspGln: 1.362 ± 0.037	2.281AspArg: 2.281 ± 0.056	3.016AspSer: 3.016 ± 0.063	2.756AspThr: 2.756 ± 0.057	3.498AspVal: 3.498 ± 0.061	0.802AspTrp: 0.802 ± 0.027	2.74AspTyr: 2.74 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	4.746GluAla: 4.746 ± 0.089	0.634GluCys: 0.634 ± 0.025	3.136GluAsp: 3.136 ± 0.057	4.754GluGlu: 4.754 ± 0.083	2.334GluPhe: 2.334 ± 0.053	3.893GluGly: 3.893 ± 0.059	1.116GluHis: 1.116 ± 0.039	4.832GluIle: 4.832 ± 0.074	5.387GluLys: 5.387 ± 0.087	6.024GluLeu: 6.024 ± 0.082	1.994GluMet: 1.994 ± 0.04	3.633GluAsn: 3.633 ± 0.058	1.767GluPro: 1.767 ± 0.042	2.576GluGln: 2.576 ± 0.045	3.013GluArg: 3.013 ± 0.059	3.197GluSer: 3.197 ± 0.056	3.291GluThr: 3.291 ± 0.051	4.189GluVal: 4.189 ± 0.067	0.774GluTrp: 0.774 ± 0.029	2.697GluTyr: 2.697 ± 0.054	0.0GluXaa: 0.0 ± 0.0
Phe	3.155PheAla: 3.155 ± 0.061	0.645PheCys: 0.645 ± 0.027	2.829PheAsp: 2.829 ± 0.055	2.527PheGlu: 2.527 ± 0.047	2.356PhePhe: 2.356 ± 0.061	3.258PheGly: 3.258 ± 0.06	0.811PheHis: 0.811 ± 0.03	3.453PheIle: 3.453 ± 0.071	2.545PheLys: 2.545 ± 0.05	4.056PheLeu: 4.056 ± 0.072	1.266PheMet: 1.266 ± 0.035	2.52PheAsn: 2.52 ± 0.055	1.814PhePro: 1.814 ± 0.04	1.238PheGln: 1.238 ± 0.034	2.117PheArg: 2.117 ± 0.048	3.565PheSer: 3.565 ± 0.061	2.803PheThr: 2.803 ± 0.063	2.953PheVal: 2.953 ± 0.057	0.519PheTrp: 0.519 ± 0.024	2.007PheTyr: 2.007 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	4.448GlyAla: 4.448 ± 0.08	0.944GlyCys: 0.944 ± 0.03	3.417GlyAsp: 3.417 ± 0.061	3.991GlyGlu: 3.991 ± 0.056	3.223GlyPhe: 3.223 ± 0.055	4.71GlyGly: 4.71 ± 0.09	1.185GlyHis: 1.185 ± 0.034	5.48GlyIle: 5.48 ± 0.083	5.446GlyLys: 5.446 ± 0.08	5.8GlyLeu: 5.8 ± 0.078	2.06GlyMet: 2.06 ± 0.046	3.691GlyAsn: 3.691 ± 0.072	1.242GlyPro: 1.242 ± 0.034	2.071GlyGln: 2.071 ± 0.048	2.754GlyArg: 2.754 ± 0.062	4.102GlySer: 4.102 ± 0.069	4.193GlyThr: 4.193 ± 0.075	4.644GlyVal: 4.644 ± 0.079	0.925GlyTrp: 0.925 ± 0.033	3.402GlyTyr: 3.402 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	1.132HisAla: 1.132 ± 0.032	0.279HisCys: 0.279 ± 0.015	0.826HisAsp: 0.826 ± 0.033	0.951HisGlu: 0.951 ± 0.031	1.007HisPhe: 1.007 ± 0.033	1.076HisGly: 1.076 ± 0.037	0.437HisHis: 0.437 ± 0.022	1.466HisIle: 1.466 ± 0.04	1.047HisLys: 1.047 ± 0.031	1.726HisLeu: 1.726 ± 0.041	0.374HisMet: 0.374 ± 0.017	0.913HisAsn: 0.913 ± 0.032	0.991HisPro: 0.991 ± 0.033	0.549HisGln: 0.549 ± 0.021	0.79HisArg: 0.79 ± 0.027	1.058HisSer: 1.058 ± 0.035	0.989HisThr: 0.989 ± 0.029	0.989HisVal: 0.989 ± 0.034	0.249HisTrp: 0.249 ± 0.015	0.839HisTyr: 0.839 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.585IleAla: 5.585 ± 0.083	0.997IleCys: 0.997 ± 0.032	4.336IleAsp: 4.336 ± 0.07	4.66IleGlu: 4.66 ± 0.066	2.973IlePhe: 2.973 ± 0.066	4.913IleGly: 4.913 ± 0.073	1.396IleHis: 1.396 ± 0.043	5.222IleIle: 5.222 ± 0.085	4.704IleLys: 4.704 ± 0.067	6.465IleLeu: 6.465 ± 0.104	1.652IleMet: 1.652 ± 0.037	3.714IleAsn: 3.714 ± 0.067	3.472IlePro: 3.472 ± 0.061	2.537IleGln: 2.537 ± 0.042	3.542IleArg: 3.542 ± 0.065	5.032IleSer: 5.032 ± 0.075	4.219IleThr: 4.219 ± 0.072	4.54IleVal: 4.54 ± 0.076	0.698IleTrp: 0.698 ± 0.029	2.916IleTyr: 2.916 ± 0.054	0.0IleXaa: 0.0 ± 0.0
Lys	4.964LysAla: 4.964 ± 0.075	0.577LysCys: 0.577 ± 0.026	4.254LysAsp: 4.254 ± 0.075	6.08LysGlu: 6.08 ± 0.091	2.17LysPhe: 2.17 ± 0.049	4.692LysGly: 4.692 ± 0.075	1.211LysHis: 1.211 ± 0.034	4.602LysIle: 4.602 ± 0.068	5.3LysLys: 5.3 ± 0.076	5.604LysLeu: 5.604 ± 0.066	2.162LysMet: 2.162 ± 0.053	3.743LysAsn: 3.743 ± 0.056	2.322LysPro: 2.322 ± 0.05	2.871LysGln: 2.871 ± 0.056	3.147LysArg: 3.147 ± 0.059	3.511LysSer: 3.511 ± 0.055	3.732LysThr: 3.732 ± 0.068	4.402LysVal: 4.402 ± 0.062	0.742LysTrp: 0.742 ± 0.03	3.012LysTyr: 3.012 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	6.377LeuAla: 6.377 ± 0.092	1.222LeuCys: 1.222 ± 0.037	4.834LeuAsp: 4.834 ± 0.08	5.021LeuGlu: 5.021 ± 0.078	4.632LeuPhe: 4.632 ± 0.075	5.676LeuGly: 5.676 ± 0.072	1.672LeuHis: 1.672 ± 0.041	6.065LeuIle: 6.065 ± 0.091	6.353LeuLys: 6.353 ± 0.085	9.179LeuLeu: 9.179 ± 0.148	2.471LeuMet: 2.471 ± 0.049	4.8LeuAsn: 4.8 ± 0.075	4.149LeuPro: 4.149 ± 0.061	3.312LeuGln: 3.312 ± 0.065	3.875LeuArg: 3.875 ± 0.062	6.835LeuSer: 6.835 ± 0.099	5.033LeuThr: 5.033 ± 0.07	5.105LeuVal: 5.105 ± 0.072	0.95LeuTrp: 0.95 ± 0.031	3.743LeuTyr: 3.743 ± 0.058	0.0LeuXaa: 0.0 ± 0.0
Met	2.112MetAla: 2.112 ± 0.051	0.253MetCys: 0.253 ± 0.016	1.565MetAsp: 1.565 ± 0.037	1.893MetGlu: 1.893 ± 0.036	1.074MetPhe: 1.074 ± 0.03	1.798MetGly: 1.798 ± 0.039	0.464MetHis: 0.464 ± 0.02	1.769MetIle: 1.769 ± 0.042	2.42MetLys: 2.42 ± 0.049	2.571MetLeu: 2.571 ± 0.05	0.774MetMet: 0.774 ± 0.032	1.627MetAsn: 1.627 ± 0.042	1.177MetPro: 1.177 ± 0.034	1.075MetGln: 1.075 ± 0.029	1.147MetArg: 1.147 ± 0.034	1.511MetSer: 1.511 ± 0.038	1.399MetThr: 1.399 ± 0.036	1.587MetVal: 1.587 ± 0.044	0.215MetTrp: 0.215 ± 0.016	0.899MetTyr: 0.899 ± 0.031	0.0MetXaa: 0.0 ± 0.0
Asn	3.532AsnAla: 3.532 ± 0.058	0.512AsnCys: 0.512 ± 0.024	2.655AsnAsp: 2.655 ± 0.052	3.175AsnGlu: 3.175 ± 0.051	2.398AsnPhe: 2.398 ± 0.047	3.899AsnGly: 3.899 ± 0.076	0.931AsnHis: 0.931 ± 0.032	4.118AsnIle: 4.118 ± 0.068	3.768AsnLys: 3.768 ± 0.055	4.483AsnLeu: 4.483 ± 0.06	1.468AsnMet: 1.468 ± 0.041	3.056AsnAsn: 3.056 ± 0.066	2.614AsnPro: 2.614 ± 0.051	1.649AsnGln: 1.649 ± 0.042	2.418AsnArg: 2.418 ± 0.052	2.898AsnSer: 2.898 ± 0.052	3.0AsnThr: 3.0 ± 0.062	3.3AsnVal: 3.3 ± 0.056	0.677AsnTrp: 0.677 ± 0.027	2.485AsnTyr: 2.485 ± 0.054	0.0AsnXaa: 0.0 ± 0.0
Pro	2.802ProAla: 2.802 ± 0.06	0.354ProCys: 0.354 ± 0.018	2.652ProAsp: 2.652 ± 0.052	3.39ProGlu: 3.39 ± 0.062	1.969ProPhe: 1.969 ± 0.05	2.474ProGly: 2.474 ± 0.053	0.66ProHis: 0.66 ± 0.027	2.343ProIle: 2.343 ± 0.046	2.097ProLys: 2.097 ± 0.041	3.353ProLeu: 3.353 ± 0.062	0.894ProMet: 0.894 ± 0.028	1.726ProAsn: 1.726 ± 0.043	0.897ProPro: 0.897 ± 0.033	1.333ProGln: 1.333 ± 0.036	1.223ProArg: 1.223 ± 0.034	2.342ProSer: 2.342 ± 0.052	1.837ProThr: 1.837 ± 0.041	3.372ProVal: 3.372 ± 0.06	0.44ProTrp: 0.44 ± 0.019	1.754ProTyr: 1.754 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.376GlnAla: 2.376 ± 0.048	0.3GlnCys: 0.3 ± 0.016	1.612GlnAsp: 1.612 ± 0.044	2.229GlnGlu: 2.229 ± 0.055	1.361GlnPhe: 1.361 ± 0.037	1.932GlnGly: 1.932 ± 0.043	0.609GlnHis: 0.609 ± 0.024	2.495GlnIle: 2.495 ± 0.052	2.572GlnLys: 2.572 ± 0.05	3.294GlnLeu: 3.294 ± 0.062	0.983GlnMet: 0.983 ± 0.027	1.752GlnAsn: 1.752 ± 0.049	1.279GlnPro: 1.279 ± 0.032	1.514GlnGln: 1.514 ± 0.044	1.475GlnArg: 1.475 ± 0.046	2.023GlnSer: 2.023 ± 0.053	1.984GlnThr: 1.984 ± 0.048	2.087GlnVal: 2.087 ± 0.037	0.402GlnTrp: 0.402 ± 0.021	1.491GlnTyr: 1.491 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	2.626ArgAla: 2.626 ± 0.052	0.441ArgCys: 0.441 ± 0.021	2.111ArgAsp: 2.111 ± 0.05	2.802ArgGlu: 2.802 ± 0.059	2.236ArgPhe: 2.236 ± 0.047	2.278ArgGly: 2.278 ± 0.053	0.813ArgHis: 0.813 ± 0.028	3.655ArgIle: 3.655 ± 0.057	3.34ArgLys: 3.34 ± 0.061	4.254ArgLeu: 4.254 ± 0.064	1.431ArgMet: 1.431 ± 0.037	2.369ArgAsn: 2.369 ± 0.047	1.522ArgPro: 1.522 ± 0.044	1.625ArgGln: 1.625 ± 0.048	1.997ArgArg: 1.997 ± 0.052	2.353ArgSer: 2.353 ± 0.054	2.306ArgThr: 2.306 ± 0.048	2.472ArgVal: 2.472 ± 0.041	0.535ArgTrp: 0.535 ± 0.024	2.018ArgTyr: 2.018 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	4.26SerAla: 4.26 ± 0.068	0.807SerCys: 0.807 ± 0.032	3.435SerAsp: 3.435 ± 0.054	3.544SerGlu: 3.544 ± 0.061	3.623SerPhe: 3.623 ± 0.067	4.703SerGly: 4.703 ± 0.084	1.051SerHis: 1.051 ± 0.031	4.615SerIle: 4.615 ± 0.07	3.582SerLys: 3.582 ± 0.052	6.075SerLeu: 6.075 ± 0.087	1.514SerMet: 1.514 ± 0.04	2.912SerAsn: 2.912 ± 0.06	2.306SerPro: 2.306 ± 0.045	1.841SerGln: 1.841 ± 0.041	2.564SerArg: 2.564 ± 0.056	4.097SerSer: 4.097 ± 0.08	3.187SerThr: 3.187 ± 0.06	4.563SerVal: 4.563 ± 0.076	0.758SerTrp: 0.758 ± 0.027	2.815SerTyr: 2.815 ± 0.056	0.0SerXaa: 0.0 ± 0.0
Thr	3.852ThrAla: 3.852 ± 0.069	0.578ThrCys: 0.578 ± 0.022	3.39ThrAsp: 3.39 ± 0.054	3.33ThrGlu: 3.33 ± 0.065	2.727ThrPhe: 2.727 ± 0.047	4.401ThrGly: 4.401 ± 0.074	0.965ThrHis: 0.965 ± 0.031	4.262ThrIle: 4.262 ± 0.062	3.006ThrLys: 3.006 ± 0.058	5.178ThrLeu: 5.178 ± 0.076	1.227ThrMet: 1.227 ± 0.038	2.655ThrAsn: 2.655 ± 0.053	2.733ThrPro: 2.733 ± 0.056	1.665ThrGln: 1.665 ± 0.037	2.074ThrArg: 2.074 ± 0.042	3.401ThrSer: 3.401 ± 0.064	3.213ThrThr: 3.213 ± 0.073	3.989ThrVal: 3.989 ± 0.076	0.589ThrTrp: 0.589 ± 0.025	2.28ThrTyr: 2.28 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	4.71ValAla: 4.71 ± 0.08	1.015ValCys: 1.015 ± 0.033	3.507ValAsp: 3.507 ± 0.064	3.803ValGlu: 3.803 ± 0.06	2.92ValPhe: 2.92 ± 0.059	3.997ValGly: 3.997 ± 0.074	1.035ValHis: 1.035 ± 0.036	4.595ValIle: 4.595 ± 0.074	4.332ValLys: 4.332 ± 0.065	5.739ValLeu: 5.739 ± 0.088	1.624ValMet: 1.624 ± 0.04	3.51ValAsn: 3.51 ± 0.056	2.641ValPro: 2.641 ± 0.05	1.876ValGln: 1.876 ± 0.035	2.794ValArg: 2.794 ± 0.054	4.764ValSer: 4.764 ± 0.067	3.793ValThr: 3.793 ± 0.067	4.338ValVal: 4.338 ± 0.076	0.737ValTrp: 0.737 ± 0.027	2.685ValTyr: 2.685 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	0.685TrpAla: 0.685 ± 0.029	0.167TrpCys: 0.167 ± 0.012	0.691TrpAsp: 0.691 ± 0.029	0.655TrpGlu: 0.655 ± 0.026	0.536TrpPhe: 0.536 ± 0.022	0.848TrpGly: 0.848 ± 0.032	0.282TrpHis: 0.282 ± 0.017	0.836TrpIle: 0.836 ± 0.03	0.896TrpLys: 0.896 ± 0.029	1.121TrpLeu: 1.121 ± 0.041	0.379TrpMet: 0.379 ± 0.017	0.754TrpAsn: 0.754 ± 0.028	0.257TrpPro: 0.257 ± 0.015	0.455TrpGln: 0.455 ± 0.02	0.521TrpArg: 0.521 ± 0.024	0.621TrpSer: 0.621 ± 0.026	0.614TrpThr: 0.614 ± 0.024	0.655TrpVal: 0.655 ± 0.029	0.159TrpTrp: 0.159 ± 0.013	0.524TrpTyr: 0.524 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.823TyrAla: 2.823 ± 0.061	0.538TyrCys: 0.538 ± 0.021	2.462TyrAsp: 2.462 ± 0.053	2.302TyrGlu: 2.302 ± 0.049	2.169TyrPhe: 2.169 ± 0.045	2.918TyrGly: 2.918 ± 0.058	0.863TyrHis: 0.863 ± 0.026	3.067TyrIle: 3.067 ± 0.057	2.98TyrLys: 2.98 ± 0.05	3.984TyrLeu: 3.984 ± 0.066	1.167TyrMet: 1.167 ± 0.033	2.6TyrAsn: 2.6 ± 0.053	1.948TyrPro: 1.948 ± 0.043	1.477TyrGln: 1.477 ± 0.037	2.028TyrArg: 2.028 ± 0.051	2.739TyrSer: 2.739 ± 0.059	2.653TyrThr: 2.653 ± 0.055	2.35TyrVal: 2.35 ± 0.051	0.594TyrTrp: 0.594 ± 0.023	2.105TyrTyr: 2.105 ± 0.053	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3041 proteins (1072125 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---