Amino acid dipepetide frequency for Cacao Bacilliform SriLanka Virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.296AlaAla: 2.296 ± 1.062
0.918AlaCys: 0.918 ± 0.47
4.132AlaAsp: 4.132 ± 1.242
3.214AlaGlu: 3.214 ± 2.758
4.132AlaPhe: 4.132 ± 2.115
1.837AlaGly: 1.837 ± 0.998
0.918AlaHis: 0.918 ± 1.406
2.755AlaIle: 2.755 ± 1.124
5.969AlaLys: 5.969 ± 4.854
5.969AlaLeu: 5.969 ± 3.242
1.837AlaMet: 1.837 ± 0.94
2.755AlaAsn: 2.755 ± 3.348
2.296AlaPro: 2.296 ± 1.047
2.755AlaGln: 2.755 ± 1.41
2.755AlaArg: 2.755 ± 1.033
5.051AlaSer: 5.051 ± 3.974
3.673AlaThr: 3.673 ± 3.516
2.755AlaVal: 2.755 ± 2.351
0.918AlaTrp: 0.918 ± 1.406
1.377AlaTyr: 1.377 ± 0.705
0.0AlaXaa: 0.0 ± 0.0
Cys
0.459CysAla: 0.459 ± 0.235
1.377CysCys: 1.377 ± 0.705
0.0CysAsp: 0.0 ± 0.0
0.459CysGlu: 0.459 ± 0.235
0.918CysPhe: 0.918 ± 0.47
0.459CysGly: 0.459 ± 0.235
0.459CysHis: 0.459 ± 0.235
0.0CysIle: 0.0 ± 0.0
4.132CysLys: 4.132 ± 2.115
0.0CysLeu: 0.0 ± 0.0
0.459CysMet: 0.459 ± 0.235
0.918CysAsn: 0.918 ± 0.47
1.377CysPro: 1.377 ± 0.705
1.377CysGln: 1.377 ± 0.705
0.459CysArg: 0.459 ± 0.235
0.459CysSer: 0.459 ± 0.235
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.459CysTyr: 0.459 ± 0.235
0.0CysXaa: 0.0 ± 0.0
Asp
2.296AspAla: 2.296 ± 1.581
0.918AspCys: 0.918 ± 0.47
2.755AspAsp: 2.755 ± 1.41
4.132AspGlu: 4.132 ± 2.022
2.296AspPhe: 2.296 ± 1.175
3.214AspGly: 3.214 ± 1.645
0.918AspHis: 0.918 ± 0.47
1.377AspIle: 1.377 ± 0.705
3.214AspLys: 3.214 ± 1.056
5.051AspLeu: 5.051 ± 2.411
0.918AspMet: 0.918 ± 0.47
2.755AspAsn: 2.755 ± 1.033
3.673AspPro: 3.673 ± 2.254
2.755AspGln: 2.755 ± 1.124
2.755AspArg: 2.755 ± 1.012
3.214AspSer: 3.214 ± 1.645
1.837AspThr: 1.837 ± 1.14
2.755AspVal: 2.755 ± 1.033
0.918AspTrp: 0.918 ± 0.47
1.837AspTyr: 1.837 ± 0.94
0.0AspXaa: 0.0 ± 0.0
Glu
7.346GluAla: 7.346 ± 1.881
0.918GluCys: 0.918 ± 0.47
5.051GluAsp: 5.051 ± 1.554
12.397GluGlu: 12.397 ± 2.061
2.296GluPhe: 2.296 ± 1.047
5.51GluGly: 5.51 ± 1.206
1.377GluHis: 1.377 ± 1.253
4.132GluIle: 4.132 ± 6.176
6.428GluLys: 6.428 ± 2.757
6.887GluLeu: 6.887 ± 3.231
1.377GluMet: 1.377 ± 0.705
2.296GluAsn: 2.296 ± 1.175
4.132GluPro: 4.132 ± 1.578
3.673GluGln: 3.673 ± 1.101
5.051GluArg: 5.051 ± 1.178
5.969GluSer: 5.969 ± 4.084
5.51GluThr: 5.51 ± 1.109
6.428GluVal: 6.428 ± 1.812
2.755GluTrp: 2.755 ± 1.012
1.377GluTyr: 1.377 ± 1.258
0.0GluXaa: 0.0 ± 0.0
Phe
2.755PheAla: 2.755 ± 1.124
1.377PheCys: 1.377 ± 0.705
1.837PheAsp: 1.837 ± 0.94
1.837PheGlu: 1.837 ± 1.13
0.459PhePhe: 0.459 ± 0.235
2.296PheGly: 2.296 ± 1.175
0.918PheHis: 0.918 ± 0.47
2.296PheIle: 2.296 ± 1.175
4.591PheLys: 4.591 ± 1.767
2.296PheLeu: 2.296 ± 1.175
0.0PheMet: 0.0 ± 0.0
2.296PheAsn: 2.296 ± 1.175
0.459PhePro: 0.459 ± 0.235
2.755PheGln: 2.755 ± 1.012
2.296PheArg: 2.296 ± 1.175
1.837PheSer: 1.837 ± 1.14
0.918PheThr: 0.918 ± 1.406
1.837PheVal: 1.837 ± 0.94
0.0PheTrp: 0.0 ± 0.0
1.837PheTyr: 1.837 ± 0.94
0.0PheXaa: 0.0 ± 0.0
Gly
1.377GlyAla: 1.377 ± 0.705
0.918GlyCys: 0.918 ± 0.47
2.296GlyAsp: 2.296 ± 1.062
5.51GlyGlu: 5.51 ± 2.82
2.755GlyPhe: 2.755 ± 1.421
2.755GlyGly: 2.755 ± 1.41
0.459GlyHis: 0.459 ± 0.235
5.51GlyIle: 5.51 ± 1.736
4.132GlyLys: 4.132 ± 2.022
4.591GlyLeu: 4.591 ± 1.767
0.0GlyMet: 0.0 ± 0.0
0.918GlyAsn: 0.918 ± 0.47
2.755GlyPro: 2.755 ± 1.41
0.918GlyGln: 0.918 ± 0.47
3.214GlyArg: 3.214 ± 1.645
3.214GlySer: 3.214 ± 2.815
3.673GlyThr: 3.673 ± 1.404
4.591GlyVal: 4.591 ± 1.357
1.377GlyTrp: 1.377 ± 0.705
1.377GlyTyr: 1.377 ± 0.705
0.0GlyXaa: 0.0 ± 0.0
His
0.459HisAla: 0.459 ± 0.235
0.459HisCys: 0.459 ± 0.235
1.377HisAsp: 1.377 ± 1.258
0.0HisGlu: 0.0 ± 0.0
1.837HisPhe: 1.837 ± 0.94
1.377HisGly: 1.377 ± 0.705
0.0HisHis: 0.0 ± 0.0
2.296HisIle: 2.296 ± 1.175
0.459HisLys: 0.459 ± 0.235
1.837HisLeu: 1.837 ± 1.14
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.918HisPro: 0.918 ± 0.47
1.377HisGln: 1.377 ± 0.705
1.377HisArg: 1.377 ± 1.253
0.918HisSer: 0.918 ± 1.404
0.0HisThr: 0.0 ± 0.0
1.377HisVal: 1.377 ± 0.705
0.459HisTrp: 0.459 ± 0.235
1.377HisTyr: 1.377 ± 0.705
0.0HisXaa: 0.0 ± 0.0
Ile
2.296IleAla: 2.296 ± 2.678
1.837IleCys: 1.837 ± 0.94
1.837IleAsp: 1.837 ± 0.94
5.51IleGlu: 5.51 ± 2.024
2.755IlePhe: 2.755 ± 1.41
3.673IleGly: 3.673 ± 1.88
2.755IleHis: 2.755 ± 1.41
5.051IleIle: 5.051 ± 2.15
4.132IleLys: 4.132 ± 1.209
5.51IleLeu: 5.51 ± 3.417
0.459IleMet: 0.459 ± 0.235
3.673IleAsn: 3.673 ± 1.101
2.296IlePro: 2.296 ± 1.175
7.346IleGln: 7.346 ± 2.554
6.887IleArg: 6.887 ± 1.868
3.673IleSer: 3.673 ± 1.101
4.132IleThr: 4.132 ± 3.994
2.755IleVal: 2.755 ± 2.029
0.0IleTrp: 0.0 ± 0.0
1.377IleTyr: 1.377 ± 1.253
0.0IleXaa: 0.0 ± 0.0
Lys
4.132LysAla: 4.132 ± 2.746
1.377LysCys: 1.377 ± 0.705
4.591LysAsp: 4.591 ± 2.073
11.019LysGlu: 11.019 ± 3.476
2.296LysPhe: 2.296 ± 1.175
4.132LysGly: 4.132 ± 1.578
3.214LysHis: 3.214 ± 1.547
5.969LysIle: 5.969 ± 3.055
4.591LysLys: 4.591 ± 2.093
6.428LysLeu: 6.428 ± 3.879
1.837LysMet: 1.837 ± 0.94
4.132LysAsn: 4.132 ± 1.213
5.51LysPro: 5.51 ± 2.251
2.296LysGln: 2.296 ± 1.531
3.673LysArg: 3.673 ± 2.645
5.51LysSer: 5.51 ± 0.944
2.296LysThr: 2.296 ± 1.175
2.755LysVal: 2.755 ± 1.012
0.459LysTrp: 0.459 ± 0.235
0.459LysTyr: 0.459 ± 0.235
0.0LysXaa: 0.0 ± 0.0
Leu
5.51LeuAla: 5.51 ± 4.703
1.377LeuCys: 1.377 ± 0.705
5.051LeuAsp: 5.051 ± 1.178
7.346LeuGlu: 7.346 ± 1.745
0.459LeuPhe: 0.459 ± 0.235
3.214LeuGly: 3.214 ± 1.031
0.459LeuHis: 0.459 ± 0.235
5.969LeuIle: 5.969 ± 3.442
7.805LeuLys: 7.805 ± 2.314
8.264LeuLeu: 8.264 ± 3.1
1.837LeuMet: 1.837 ± 0.94
5.969LeuAsn: 5.969 ± 3.055
4.132LeuPro: 4.132 ± 1.113
6.887LeuGln: 6.887 ± 1.763
4.591LeuArg: 4.591 ± 2.014
6.428LeuSer: 6.428 ± 6.025
4.591LeuThr: 4.591 ± 2.256
6.428LeuVal: 6.428 ± 2.062
0.459LeuTrp: 0.459 ± 1.575
4.132LeuTyr: 4.132 ± 2.485
0.0LeuXaa: 0.0 ± 0.0
Met
0.459MetAla: 0.459 ± 0.235
0.459MetCys: 0.459 ± 0.235
1.377MetAsp: 1.377 ± 0.705
2.755MetGlu: 2.755 ± 1.41
0.459MetPhe: 0.459 ± 0.235
0.918MetGly: 0.918 ± 0.47
0.0MetHis: 0.0 ± 0.0
1.837MetIle: 1.837 ± 0.94
2.296MetLys: 2.296 ± 1.175
1.377MetLeu: 1.377 ± 0.705
1.377MetMet: 1.377 ± 0.705
0.459MetAsn: 0.459 ± 0.235
1.377MetPro: 1.377 ± 0.705
0.459MetGln: 0.459 ± 0.235
0.459MetArg: 0.459 ± 0.235
2.755MetSer: 2.755 ± 3.923
0.918MetThr: 0.918 ± 0.47
1.837MetVal: 1.837 ± 0.94
0.0MetTrp: 0.0 ± 0.0
0.918MetTyr: 0.918 ± 0.47
0.0MetXaa: 0.0 ± 0.0
Asn
1.837AsnAla: 1.837 ± 1.14
0.0AsnCys: 0.0 ± 0.0
2.296AsnAsp: 2.296 ± 2.658
2.296AsnGlu: 2.296 ± 1.175
0.918AsnPhe: 0.918 ± 0.47
3.673AsnGly: 3.673 ± 1.88
0.0AsnHis: 0.0 ± 0.0
2.296AsnIle: 2.296 ± 1.175
2.755AsnLys: 2.755 ± 1.41
7.346AsnLeu: 7.346 ± 4.418
0.918AsnMet: 0.918 ± 0.47
2.755AsnAsn: 2.755 ± 1.362
2.296AsnPro: 2.296 ± 1.175
3.673AsnGln: 3.673 ± 1.129
2.755AsnArg: 2.755 ± 1.033
1.837AsnSer: 1.837 ± 0.94
2.755AsnThr: 2.755 ± 1.41
1.837AsnVal: 1.837 ± 0.94
0.459AsnTrp: 0.459 ± 0.235
2.296AsnTyr: 2.296 ± 1.047
0.0AsnXaa: 0.0 ± 0.0
Pro
3.673ProAla: 3.673 ± 1.404
0.0ProCys: 0.0 ± 0.0
1.837ProAsp: 1.837 ± 0.94
3.214ProGlu: 3.214 ± 1.645
1.377ProPhe: 1.377 ± 0.705
2.296ProGly: 2.296 ± 1.062
0.918ProHis: 0.918 ± 0.47
3.214ProIle: 3.214 ± 1.284
3.214ProLys: 3.214 ± 4.053
5.51ProLeu: 5.51 ± 0.944
0.459ProMet: 0.459 ± 0.235
2.296ProAsn: 2.296 ± 1.175
2.755ProPro: 2.755 ± 1.124
0.918ProGln: 0.918 ± 0.47
2.755ProArg: 2.755 ± 1.41
4.591ProSer: 4.591 ± 1.387
3.214ProThr: 3.214 ± 1.031
2.296ProVal: 2.296 ± 1.037
1.377ProTrp: 1.377 ± 0.705
1.377ProTyr: 1.377 ± 0.705
0.0ProXaa: 0.0 ± 0.0
Gln
2.296GlnAla: 2.296 ± 1.047
0.0GlnCys: 0.0 ± 0.0
2.296GlnAsp: 2.296 ± 1.175
4.591GlnGlu: 4.591 ± 1.079
1.837GlnPhe: 1.837 ± 0.94
2.755GlnGly: 2.755 ± 1.033
1.837GlnHis: 1.837 ± 0.94
4.132GlnIle: 4.132 ± 1.022
5.051GlnLys: 5.051 ± 1.554
5.051GlnLeu: 5.051 ± 1.178
0.459GlnMet: 0.459 ± 0.235
2.755GlnAsn: 2.755 ± 1.124
3.214GlnPro: 3.214 ± 1.031
3.214GlnGln: 3.214 ± 1.645
5.051GlnArg: 5.051 ± 2.585
2.296GlnSer: 2.296 ± 1.175
1.837GlnThr: 1.837 ± 1.13
2.296GlnVal: 2.296 ± 1.175
1.377GlnTrp: 1.377 ± 0.705
2.755GlnTyr: 2.755 ± 1.738
0.0GlnXaa: 0.0 ± 0.0
Arg
4.132ArgAla: 4.132 ± 3.775
0.918ArgCys: 0.918 ± 0.47
1.837ArgAsp: 1.837 ± 0.94
5.51ArgGlu: 5.51 ± 3.477
2.755ArgPhe: 2.755 ± 1.738
2.755ArgGly: 2.755 ± 1.41
0.459ArgHis: 0.459 ± 0.235
5.51ArgIle: 5.51 ± 1.768
4.591ArgLys: 4.591 ± 2.35
4.132ArgLeu: 4.132 ± 2.115
3.673ArgMet: 3.673 ± 1.541
1.837ArgAsn: 1.837 ± 1.716
2.755ArgPro: 2.755 ± 1.012
1.377ArgGln: 1.377 ± 1.258
5.969ArgArg: 5.969 ± 4.903
5.051ArgSer: 5.051 ± 1.128
3.673ArgThr: 3.673 ± 1.88
2.755ArgVal: 2.755 ± 1.738
1.377ArgTrp: 1.377 ± 0.705
0.918ArgTyr: 0.918 ± 0.47
0.0ArgXaa: 0.0 ± 0.0
Ser
6.428SerAla: 6.428 ± 6.475
0.459SerCys: 0.459 ± 0.235
2.296SerAsp: 2.296 ± 1.581
5.969SerGlu: 5.969 ± 5.279
3.214SerPhe: 3.214 ± 1.645
4.591SerGly: 4.591 ± 1.767
0.459SerHis: 0.459 ± 0.235
5.051SerIle: 5.051 ± 2.399
2.755SerLys: 2.755 ± 1.033
5.969SerLeu: 5.969 ± 3.292
2.296SerMet: 2.296 ± 0.979
1.837SerAsn: 1.837 ± 1.758
1.837SerPro: 1.837 ± 0.94
4.591SerGln: 4.591 ± 1.357
4.591SerArg: 4.591 ± 0.998
6.428SerSer: 6.428 ± 8.365
3.673SerThr: 3.673 ± 2.645
2.296SerVal: 2.296 ± 1.047
0.918SerTrp: 0.918 ± 0.47
3.214SerTyr: 3.214 ± 1.25
0.0SerXaa: 0.0 ± 0.0
Thr
2.296ThrAla: 2.296 ± 1.037
0.459ThrCys: 0.459 ± 0.235
3.214ThrAsp: 3.214 ± 1.25
6.887ThrGlu: 6.887 ± 1.542
0.918ThrPhe: 0.918 ± 0.47
4.591ThrGly: 4.591 ± 1.096
1.377ThrHis: 1.377 ± 0.705
3.214ThrIle: 3.214 ± 1.25
3.673ThrLys: 3.673 ± 3.432
3.673ThrLeu: 3.673 ± 1.101
1.837ThrMet: 1.837 ± 1.14
1.837ThrAsn: 1.837 ± 1.14
1.377ThrPro: 1.377 ± 1.253
1.837ThrGln: 1.837 ± 2.812
2.296ThrArg: 2.296 ± 1.94
4.132ThrSer: 4.132 ± 1.213
1.837ThrThr: 1.837 ± 1.14
3.214ThrVal: 3.214 ± 1.25
0.459ThrTrp: 0.459 ± 0.235
1.377ThrTyr: 1.377 ± 0.705
0.0ThrXaa: 0.0 ± 0.0
Val
3.214ValAla: 3.214 ± 1.25
0.0ValCys: 0.0 ± 0.0
4.591ValAsp: 4.591 ± 1.767
3.214ValGlu: 3.214 ± 3.698
2.296ValPhe: 2.296 ± 1.037
0.918ValGly: 0.918 ± 1.083
0.459ValHis: 0.459 ± 0.235
5.51ValIle: 5.51 ± 1.992
2.296ValLys: 2.296 ± 1.531
5.051ValLeu: 5.051 ± 0.988
1.377ValMet: 1.377 ± 0.705
1.837ValAsn: 1.837 ± 0.94
2.755ValPro: 2.755 ± 1.41
3.214ValGln: 3.214 ± 1.031
3.214ValArg: 3.214 ± 1.031
3.673ValSer: 3.673 ± 1.101
3.673ValThr: 3.673 ± 1.101
1.377ValVal: 1.377 ± 1.015
0.0ValTrp: 0.0 ± 0.0
1.377ValTyr: 1.377 ± 0.705
0.0ValXaa: 0.0 ± 0.0
Trp
1.837TrpAla: 1.837 ± 0.94
0.0TrpCys: 0.0 ± 0.0
0.459TrpAsp: 0.459 ± 0.235
1.377TrpGlu: 1.377 ± 1.258
0.0TrpPhe: 0.0 ± 0.0
0.918TrpGly: 0.918 ± 1.406
0.459TrpHis: 0.459 ± 0.235
0.459TrpIle: 0.459 ± 0.235
1.377TrpLys: 1.377 ± 0.705
1.377TrpLeu: 1.377 ± 0.705
0.0TrpMet: 0.0 ± 0.0
0.918TrpAsn: 0.918 ± 0.47
0.459TrpPro: 0.459 ± 0.235
1.377TrpGln: 1.377 ± 0.705
0.918TrpArg: 0.918 ± 0.47
0.0TrpSer: 0.0 ± 0.0
1.377TrpThr: 1.377 ± 0.705
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.459TrpTyr: 0.459 ± 1.576
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.214TyrAla: 3.214 ± 1.547
0.0TyrCys: 0.0 ± 0.0
0.459TyrAsp: 0.459 ± 1.576
3.673TyrGlu: 3.673 ± 1.129
0.918TyrPhe: 0.918 ± 0.47
0.459TyrGly: 0.459 ± 0.235
0.459TyrHis: 0.459 ± 0.235
1.377TyrIle: 1.377 ± 0.705
3.214TyrLys: 3.214 ± 1.214
4.591TyrLeu: 4.591 ± 1.079
0.918TyrMet: 0.918 ± 0.987
2.755TyrAsn: 2.755 ± 1.41
0.918TyrPro: 0.918 ± 0.47
2.296TyrGln: 2.296 ± 1.175
1.377TyrArg: 1.377 ± 0.705
1.837TyrSer: 1.837 ± 0.94
0.918TyrThr: 0.918 ± 0.47
0.459TyrVal: 0.459 ± 1.194
0.459TyrTrp: 0.459 ± 0.235
1.377TyrTyr: 1.377 ± 0.705
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2179 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski