Amino acid dipepetide frequency for Bovine herpesvirus 4 (BoHV-4) (Movar virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.753AlaAla: 2.753 ± 0.26
1.021AlaCys: 1.021 ± 0.199
1.454AlaAsp: 1.454 ± 0.205
1.546AlaGlu: 1.546 ± 0.246
1.825AlaPhe: 1.825 ± 0.261
1.794AlaGly: 1.794 ± 0.312
1.392AlaHis: 1.392 ± 0.222
3.804AlaIle: 3.804 ± 0.258
2.072AlaLys: 2.072 ± 0.21
5.041AlaLeu: 5.041 ± 0.375
1.515AlaMet: 1.515 ± 0.241
2.598AlaAsn: 2.598 ± 0.324
2.753AlaPro: 2.753 ± 0.305
2.041AlaGln: 2.041 ± 0.328
1.979AlaArg: 1.979 ± 0.247
4.144AlaSer: 4.144 ± 0.426
3.402AlaThr: 3.402 ± 0.333
2.165AlaVal: 2.165 ± 0.308
0.433AlaTrp: 0.433 ± 0.131
1.701AlaTyr: 1.701 ± 0.386
0.0AlaXaa: 0.0 ± 0.0
Cys
1.237CysAla: 1.237 ± 0.2
0.773CysCys: 0.773 ± 0.172
1.206CysAsp: 1.206 ± 0.223
1.144CysGlu: 1.144 ± 0.186
1.763CysPhe: 1.763 ± 0.27
1.423CysGly: 1.423 ± 0.265
1.021CysHis: 1.021 ± 0.198
1.608CysIle: 1.608 ± 0.237
1.33CysLys: 1.33 ± 0.216
3.402CysLeu: 3.402 ± 0.466
0.526CysMet: 0.526 ± 0.134
0.99CysAsn: 0.99 ± 0.157
1.485CysPro: 1.485 ± 0.181
1.361CysGln: 1.361 ± 0.236
0.866CysArg: 0.866 ± 0.181
1.608CysSer: 1.608 ± 0.264
1.454CysThr: 1.454 ± 0.197
1.608CysVal: 1.608 ± 0.25
0.402CysTrp: 0.402 ± 0.125
0.773CysTyr: 0.773 ± 0.148
0.0CysXaa: 0.0 ± 0.0
Asp
2.103AspAla: 2.103 ± 0.304
1.144AspCys: 1.144 ± 0.227
2.474AspAsp: 2.474 ± 0.328
2.165AspGlu: 2.165 ± 0.398
2.072AspPhe: 2.072 ± 0.303
2.103AspGly: 2.103 ± 0.313
1.299AspHis: 1.299 ± 0.213
4.299AspIle: 4.299 ± 0.344
2.783AspLys: 2.783 ± 0.397
5.443AspLeu: 5.443 ± 0.34
1.67AspMet: 1.67 ± 0.279
2.165AspAsn: 2.165 ± 0.28
2.814AspPro: 2.814 ± 0.295
1.454AspGln: 1.454 ± 0.19
1.763AspArg: 1.763 ± 0.25
3.433AspSer: 3.433 ± 0.308
3.804AspThr: 3.804 ± 0.341
3.495AspVal: 3.495 ± 0.372
0.557AspTrp: 0.557 ± 0.122
1.639AspTyr: 1.639 ± 0.214
0.0AspXaa: 0.0 ± 0.0
Glu
2.814GluAla: 2.814 ± 0.341
1.299GluCys: 1.299 ± 0.253
3.526GluAsp: 3.526 ± 0.477
3.186GluGlu: 3.186 ± 0.525
2.041GluPhe: 2.041 ± 0.208
1.732GluGly: 1.732 ± 0.299
1.392GluHis: 1.392 ± 0.254
3.742GluIle: 3.742 ± 0.424
2.845GluLys: 2.845 ± 0.271
4.206GluLeu: 4.206 ± 0.328
1.206GluMet: 1.206 ± 0.188
3.186GluAsn: 3.186 ± 0.37
2.01GluPro: 2.01 ± 0.274
1.67GluGln: 1.67 ± 0.24
1.825GluArg: 1.825 ± 0.217
3.495GluSer: 3.495 ± 0.387
3.928GluThr: 3.928 ± 0.37
2.814GluVal: 2.814 ± 0.283
0.34GluTrp: 0.34 ± 0.108
1.392GluTyr: 1.392 ± 0.187
0.0GluXaa: 0.0 ± 0.0
Phe
1.206PheAla: 1.206 ± 0.186
1.268PheCys: 1.268 ± 0.175
1.979PheAsp: 1.979 ± 0.199
1.979PheGlu: 1.979 ± 0.286
3.155PhePhe: 3.155 ± 0.382
2.258PheGly: 2.258 ± 0.351
1.175PheHis: 1.175 ± 0.183
4.113PheIle: 4.113 ± 0.392
3.278PheLys: 3.278 ± 0.353
5.783PheLeu: 5.783 ± 0.466
1.701PheMet: 1.701 ± 0.235
2.196PheAsn: 2.196 ± 0.279
2.32PhePro: 2.32 ± 0.224
1.732PheGln: 1.732 ± 0.179
1.67PheArg: 1.67 ± 0.209
3.773PheSer: 3.773 ± 0.376
3.433PheThr: 3.433 ± 0.437
2.567PheVal: 2.567 ± 0.362
0.34PheTrp: 0.34 ± 0.136
2.66PheTyr: 2.66 ± 0.31
0.0PheXaa: 0.0 ± 0.0
Gly
2.196GlyAla: 2.196 ± 0.362
1.392GlyCys: 1.392 ± 0.263
3.155GlyAsp: 3.155 ± 0.371
3.031GlyGlu: 3.031 ± 0.324
2.196GlyPhe: 2.196 ± 0.301
2.289GlyGly: 2.289 ± 0.367
1.021GlyHis: 1.021 ± 0.132
2.753GlyIle: 2.753 ± 0.299
2.381GlyLys: 2.381 ± 0.287
4.917GlyLeu: 4.917 ± 0.502
1.33GlyMet: 1.33 ± 0.211
2.443GlyAsn: 2.443 ± 0.301
2.567GlyPro: 2.567 ± 0.307
1.608GlyGln: 1.608 ± 0.214
2.103GlyArg: 2.103 ± 0.337
3.402GlySer: 3.402 ± 0.373
2.783GlyThr: 2.783 ± 0.312
2.876GlyVal: 2.876 ± 0.359
0.526GlyTrp: 0.526 ± 0.12
1.794GlyTyr: 1.794 ± 0.23
0.0GlyXaa: 0.0 ± 0.0
His
1.052HisAla: 1.052 ± 0.164
0.804HisCys: 0.804 ± 0.14
1.268HisAsp: 1.268 ± 0.189
1.33HisGlu: 1.33 ± 0.265
1.546HisPhe: 1.546 ± 0.252
1.732HisGly: 1.732 ± 0.302
0.99HisHis: 0.99 ± 0.167
2.505HisIle: 2.505 ± 0.345
1.763HisLys: 1.763 ± 0.253
3.247HisLeu: 3.247 ± 0.345
0.619HisMet: 0.619 ± 0.198
1.144HisAsn: 1.144 ± 0.2
1.485HisPro: 1.485 ± 0.202
1.082HisGln: 1.082 ± 0.157
1.144HisArg: 1.144 ± 0.244
1.577HisSer: 1.577 ± 0.208
1.546HisThr: 1.546 ± 0.235
2.134HisVal: 2.134 ± 0.236
0.433HisTrp: 0.433 ± 0.121
0.835HisTyr: 0.835 ± 0.166
0.0HisXaa: 0.0 ± 0.0
Ile
2.258IleAla: 2.258 ± 0.289
1.917IleCys: 1.917 ± 0.274
3.526IleAsp: 3.526 ± 0.403
3.124IleGlu: 3.124 ± 0.39
3.866IlePhe: 3.866 ± 0.423
2.876IleGly: 2.876 ± 0.355
1.948IleHis: 1.948 ± 0.224
5.258IleIle: 5.258 ± 0.502
4.67IleLys: 4.67 ± 0.378
7.763IleLeu: 7.763 ± 0.533
1.67IleMet: 1.67 ± 0.257
4.732IleAsn: 4.732 ± 0.393
4.144IlePro: 4.144 ± 0.399
3.526IleGln: 3.526 ± 0.454
2.32IleArg: 2.32 ± 0.282
7.237IleSer: 7.237 ± 0.529
4.701IleThr: 4.701 ± 0.327
3.186IleVal: 3.186 ± 0.432
0.557IleTrp: 0.557 ± 0.131
3.216IleTyr: 3.216 ± 0.35
0.0IleXaa: 0.0 ± 0.0
Lys
1.763LysAla: 1.763 ± 0.232
1.361LysCys: 1.361 ± 0.255
3.495LysAsp: 3.495 ± 0.25
3.216LysGlu: 3.216 ± 0.354
2.381LysPhe: 2.381 ± 0.223
2.165LysGly: 2.165 ± 0.29
2.32LysHis: 2.32 ± 0.341
3.959LysIle: 3.959 ± 0.375
4.33LysLys: 4.33 ± 0.493
5.845LysLeu: 5.845 ± 0.607
1.917LysMet: 1.917 ± 0.192
3.742LysAsn: 3.742 ± 0.425
2.66LysPro: 2.66 ± 0.456
2.938LysGln: 2.938 ± 0.327
2.66LysArg: 2.66 ± 0.306
4.175LysSer: 4.175 ± 0.496
4.608LysThr: 4.608 ± 0.431
3.371LysVal: 3.371 ± 0.389
0.216LysTrp: 0.216 ± 0.081
2.32LysTyr: 2.32 ± 0.275
0.0LysXaa: 0.0 ± 0.0
Leu
4.948LeuAla: 4.948 ± 0.385
2.505LeuCys: 2.505 ± 0.358
4.546LeuAsp: 4.546 ± 0.445
5.876LeuGlu: 5.876 ± 0.501
5.381LeuPhe: 5.381 ± 0.455
4.917LeuGly: 4.917 ± 0.411
2.35LeuHis: 2.35 ± 0.235
5.938LeuIle: 5.938 ± 0.458
6.742LeuLys: 6.742 ± 0.468
9.989LeuLeu: 9.989 ± 0.595
2.381LeuMet: 2.381 ± 0.252
5.165LeuAsn: 5.165 ± 0.473
5.227LeuPro: 5.227 ± 0.506
4.484LeuGln: 4.484 ± 0.513
3.557LeuArg: 3.557 ± 0.349
8.35LeuSer: 8.35 ± 0.515
6.804LeuThr: 6.804 ± 0.51
5.289LeuVal: 5.289 ± 0.563
0.99LeuTrp: 0.99 ± 0.166
4.206LeuTyr: 4.206 ± 0.441
0.0LeuXaa: 0.0 ± 0.0
Met
2.103MetAla: 2.103 ± 0.285
0.526MetCys: 0.526 ± 0.129
1.608MetAsp: 1.608 ± 0.207
1.67MetGlu: 1.67 ± 0.207
1.608MetPhe: 1.608 ± 0.249
1.763MetGly: 1.763 ± 0.274
0.557MetHis: 0.557 ± 0.123
1.577MetIle: 1.577 ± 0.213
1.237MetLys: 1.237 ± 0.21
2.165MetLeu: 2.165 ± 0.305
0.619MetMet: 0.619 ± 0.141
1.299MetAsn: 1.299 ± 0.216
0.742MetPro: 0.742 ± 0.155
0.68MetGln: 0.68 ± 0.147
0.773MetArg: 0.773 ± 0.184
2.196MetSer: 2.196 ± 0.317
1.485MetThr: 1.485 ± 0.247
1.887MetVal: 1.887 ± 0.348
0.371MetTrp: 0.371 ± 0.098
1.423MetTyr: 1.423 ± 0.238
0.0MetXaa: 0.0 ± 0.0
Asn
2.103AsnAla: 2.103 ± 0.297
1.454AsnCys: 1.454 ± 0.235
1.577AsnAsp: 1.577 ± 0.249
2.134AsnGlu: 2.134 ± 0.328
2.381AsnPhe: 2.381 ± 0.307
2.35AsnGly: 2.35 ± 0.37
1.237AsnHis: 1.237 ± 0.22
5.845AsnIle: 5.845 ± 0.494
3.371AsnLys: 3.371 ± 0.27
5.072AsnLeu: 5.072 ± 0.402
1.237AsnMet: 1.237 ± 0.217
3.68AsnAsn: 3.68 ± 0.302
2.691AsnPro: 2.691 ± 0.322
2.289AsnGln: 2.289 ± 0.3
1.701AsnArg: 1.701 ± 0.287
4.423AsnSer: 4.423 ± 0.383
4.484AsnThr: 4.484 ± 0.41
2.938AsnVal: 2.938 ± 0.432
0.588AsnTrp: 0.588 ± 0.125
2.01AsnTyr: 2.01 ± 0.327
0.0AsnXaa: 0.0 ± 0.0
Pro
1.794ProAla: 1.794 ± 0.259
1.392ProCys: 1.392 ± 0.223
2.814ProAsp: 2.814 ± 0.322
2.35ProGlu: 2.35 ± 0.333
1.763ProPhe: 1.763 ± 0.216
3.526ProGly: 3.526 ± 0.341
1.485ProHis: 1.485 ± 0.209
3.557ProIle: 3.557 ± 0.516
3.124ProLys: 3.124 ± 0.537
5.041ProLeu: 5.041 ± 0.527
1.392ProMet: 1.392 ± 0.3
2.536ProAsn: 2.536 ± 0.277
6.34ProPro: 6.34 ± 1.191
3.186ProGln: 3.186 ± 0.621
2.32ProArg: 2.32 ± 0.307
4.608ProSer: 4.608 ± 0.387
4.144ProThr: 4.144 ± 0.467
3.618ProVal: 3.618 ± 0.345
0.68ProTrp: 0.68 ± 0.126
1.794ProTyr: 1.794 ± 0.239
0.0ProXaa: 0.0 ± 0.0
Gln
2.536GlnAla: 2.536 ± 0.375
1.268GlnCys: 1.268 ± 0.234
2.443GlnAsp: 2.443 ± 0.309
2.165GlnGlu: 2.165 ± 0.257
1.763GlnPhe: 1.763 ± 0.214
2.227GlnGly: 2.227 ± 0.278
1.206GlnHis: 1.206 ± 0.217
2.505GlnIle: 2.505 ± 0.311
2.938GlnLys: 2.938 ± 0.297
3.526GlnLeu: 3.526 ± 0.335
0.804GlnMet: 0.804 ± 0.178
2.072GlnAsn: 2.072 ± 0.229
2.041GlnPro: 2.041 ± 0.447
1.917GlnGln: 1.917 ± 0.234
1.794GlnArg: 1.794 ± 0.308
2.969GlnSer: 2.969 ± 0.312
2.536GlnThr: 2.536 ± 0.278
1.887GlnVal: 1.887 ± 0.222
0.742GlnTrp: 0.742 ± 0.181
2.01GlnTyr: 2.01 ± 0.35
0.0GlnXaa: 0.0 ± 0.0
Arg
2.165ArgAla: 2.165 ± 0.233
1.021ArgCys: 1.021 ± 0.185
2.258ArgAsp: 2.258 ± 0.388
2.443ArgGlu: 2.443 ± 0.293
1.546ArgPhe: 1.546 ± 0.224
2.381ArgGly: 2.381 ± 0.378
1.268ArgHis: 1.268 ± 0.219
1.979ArgIle: 1.979 ± 0.215
2.381ArgLys: 2.381 ± 0.303
3.804ArgLeu: 3.804 ± 0.371
0.99ArgMet: 0.99 ± 0.213
1.67ArgAsn: 1.67 ± 0.211
2.227ArgPro: 2.227 ± 0.32
1.361ArgGln: 1.361 ± 0.219
1.825ArgArg: 1.825 ± 0.268
2.103ArgSer: 2.103 ± 0.231
2.32ArgThr: 2.32 ± 0.27
2.103ArgVal: 2.103 ± 0.278
0.495ArgTrp: 0.495 ± 0.099
1.423ArgTyr: 1.423 ± 0.26
0.0ArgXaa: 0.0 ± 0.0
Ser
3.186SerAla: 3.186 ± 0.326
1.917SerCys: 1.917 ± 0.225
4.206SerAsp: 4.206 ± 0.392
3.309SerGlu: 3.309 ± 0.385
3.866SerPhe: 3.866 ± 0.307
3.433SerGly: 3.433 ± 0.326
2.474SerHis: 2.474 ± 0.319
6.062SerIle: 6.062 ± 0.436
4.237SerLys: 4.237 ± 0.426
8.134SerLeu: 8.134 ± 0.61
2.35SerMet: 2.35 ± 0.285
3.773SerAsn: 3.773 ± 0.309
4.763SerPro: 4.763 ± 0.448
3.526SerGln: 3.526 ± 0.374
2.845SerArg: 2.845 ± 0.247
7.608SerSer: 7.608 ± 0.998
7.175SerThr: 7.175 ± 0.955
4.608SerVal: 4.608 ± 0.332
0.526SerTrp: 0.526 ± 0.145
2.598SerTyr: 2.598 ± 0.271
0.0SerXaa: 0.0 ± 0.0
Thr
3.928ThrAla: 3.928 ± 0.397
1.577ThrCys: 1.577 ± 0.271
3.031ThrAsp: 3.031 ± 0.362
2.598ThrGlu: 2.598 ± 0.266
3.68ThrPhe: 3.68 ± 0.352
2.938ThrGly: 2.938 ± 0.272
2.629ThrHis: 2.629 ± 0.281
5.258ThrIle: 5.258 ± 0.407
3.309ThrLys: 3.309 ± 0.383
6.309ThrLeu: 6.309 ± 0.53
1.485ThrMet: 1.485 ± 0.247
3.68ThrAsn: 3.68 ± 0.381
4.917ThrPro: 4.917 ± 0.531
2.691ThrGln: 2.691 ± 0.315
2.567ThrArg: 2.567 ± 0.301
6.773ThrSer: 6.773 ± 0.965
5.783ThrThr: 5.783 ± 0.723
4.33ThrVal: 4.33 ± 0.493
0.835ThrTrp: 0.835 ± 0.136
2.969ThrTyr: 2.969 ± 0.328
0.0ThrXaa: 0.0 ± 0.0
Val
3.124ValAla: 3.124 ± 0.438
1.763ValCys: 1.763 ± 0.268
2.32ValAsp: 2.32 ± 0.314
3.186ValGlu: 3.186 ± 0.349
3.278ValPhe: 3.278 ± 0.345
2.35ValGly: 2.35 ± 0.383
1.392ValHis: 1.392 ± 0.222
3.495ValIle: 3.495 ± 0.371
3.711ValLys: 3.711 ± 0.356
5.289ValLeu: 5.289 ± 0.462
1.454ValMet: 1.454 ± 0.237
3.186ValAsn: 3.186 ± 0.329
3.216ValPro: 3.216 ± 0.319
2.505ValGln: 2.505 ± 0.301
2.258ValArg: 2.258 ± 0.316
5.041ValSer: 5.041 ± 0.566
3.866ValThr: 3.866 ± 0.307
3.649ValVal: 3.649 ± 0.493
0.649ValTrp: 0.649 ± 0.149
2.598ValTyr: 2.598 ± 0.35
0.0ValXaa: 0.0 ± 0.0
Trp
0.711TrpAla: 0.711 ± 0.156
0.371TrpCys: 0.371 ± 0.133
0.34TrpAsp: 0.34 ± 0.112
0.557TrpGlu: 0.557 ± 0.169
0.557TrpPhe: 0.557 ± 0.117
0.557TrpGly: 0.557 ± 0.148
0.155TrpHis: 0.155 ± 0.078
0.897TrpIle: 0.897 ± 0.184
0.464TrpLys: 0.464 ± 0.105
1.082TrpLeu: 1.082 ± 0.175
0.247TrpMet: 0.247 ± 0.079
0.526TrpAsn: 0.526 ± 0.146
0.897TrpPro: 0.897 ± 0.164
0.402TrpGln: 0.402 ± 0.099
0.34TrpArg: 0.34 ± 0.097
0.526TrpSer: 0.526 ± 0.138
0.557TrpThr: 0.557 ± 0.169
0.68TrpVal: 0.68 ± 0.145
0.062TrpTrp: 0.062 ± 0.037
0.371TrpTyr: 0.371 ± 0.103
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.454TyrAla: 1.454 ± 0.169
1.206TyrCys: 1.206 ± 0.205
1.454TyrAsp: 1.454 ± 0.229
1.639TyrGlu: 1.639 ± 0.207
1.917TyrPhe: 1.917 ± 0.242
1.948TyrGly: 1.948 ± 0.219
0.928TyrHis: 0.928 ± 0.16
3.34TyrIle: 3.34 ± 0.323
2.474TyrLys: 2.474 ± 0.315
3.588TyrLeu: 3.588 ± 0.457
1.144TyrMet: 1.144 ± 0.204
2.783TyrAsn: 2.783 ± 0.387
2.196TyrPro: 2.196 ± 0.291
0.897TyrGln: 0.897 ± 0.132
1.454TyrArg: 1.454 ± 0.197
3.155TyrSer: 3.155 ± 0.292
2.474TyrThr: 2.474 ± 0.306
3.124TyrVal: 3.124 ± 0.443
0.557TyrTrp: 0.557 ± 0.122
1.423TyrTyr: 1.423 ± 0.254
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 78 proteins (32335 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski