Amino acid dipepetide frequency for Elderberry carlavirus E

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.832AlaAla: 6.832 ± 1.027
1.438AlaCys: 1.438 ± 1.01
3.955AlaAsp: 3.955 ± 0.663
4.315AlaGlu: 4.315 ± 2.846
3.596AlaPhe: 3.596 ± 1.147
4.675AlaGly: 4.675 ± 0.993
2.157AlaHis: 2.157 ± 0.432
5.753AlaIle: 5.753 ± 1.308
7.192AlaLys: 7.192 ± 3.206
9.349AlaLeu: 9.349 ± 2.171
1.798AlaMet: 1.798 ± 0.693
5.394AlaAsn: 5.394 ± 1.819
2.877AlaPro: 2.877 ± 1.107
2.157AlaGln: 2.157 ± 1.148
4.315AlaArg: 4.315 ± 2.353
5.034AlaSer: 5.034 ± 2.081
4.315AlaThr: 4.315 ± 1.763
4.675AlaVal: 4.675 ± 1.564
0.719AlaTrp: 0.719 ± 0.526
1.798AlaTyr: 1.798 ± 0.956
0.0AlaXaa: 0.0 ± 0.0
Cys
2.517CysAla: 2.517 ± 0.873
0.0CysCys: 0.0 ± 0.0
0.719CysAsp: 0.719 ± 0.73
1.798CysGlu: 1.798 ± 0.904
2.157CysPhe: 2.157 ± 0.795
2.157CysGly: 2.157 ± 0.782
0.0CysHis: 0.0 ± 0.0
0.719CysIle: 0.719 ± 0.383
0.36CysLys: 0.36 ± 0.191
2.157CysLeu: 2.157 ± 0.869
0.36CysMet: 0.36 ± 0.765
1.079CysAsn: 1.079 ± 1.099
0.719CysPro: 0.719 ± 0.627
1.438CysGln: 1.438 ± 1.426
0.719CysArg: 0.719 ± 0.383
1.438CysSer: 1.438 ± 0.745
3.955CysThr: 3.955 ± 1.065
1.798CysVal: 1.798 ± 0.864
0.36CysTrp: 0.36 ± 0.831
0.36CysTyr: 0.36 ± 0.191
0.0CysXaa: 0.0 ± 0.0
Asp
3.596AspAla: 3.596 ± 1.166
0.719AspCys: 0.719 ± 0.383
1.438AspAsp: 1.438 ± 0.765
4.675AspGlu: 4.675 ± 0.833
1.798AspPhe: 1.798 ± 0.55
2.517AspGly: 2.517 ± 1.083
0.36AspHis: 0.36 ± 0.191
4.675AspIle: 4.675 ± 1.4
1.798AspLys: 1.798 ± 0.536
6.113AspLeu: 6.113 ± 1.638
1.438AspMet: 1.438 ± 0.606
1.079AspAsn: 1.079 ± 0.574
2.517AspPro: 2.517 ± 0.899
1.438AspGln: 1.438 ± 0.567
3.955AspArg: 3.955 ± 2.332
1.798AspSer: 1.798 ± 0.971
2.157AspThr: 2.157 ± 1.683
1.798AspVal: 1.798 ± 0.956
1.079AspTrp: 1.079 ± 0.461
2.877AspTyr: 2.877 ± 0.452
0.0AspXaa: 0.0 ± 0.0
Glu
5.034GluAla: 5.034 ± 1.488
0.36GluCys: 0.36 ± 0.191
2.517GluAsp: 2.517 ± 0.873
4.675GluGlu: 4.675 ± 1.237
2.517GluPhe: 2.517 ± 0.76
4.675GluGly: 4.675 ± 0.833
4.315GluHis: 4.315 ± 1.844
3.955GluIle: 3.955 ± 0.663
3.236GluLys: 3.236 ± 1.192
8.63GluLeu: 8.63 ± 2.643
1.079GluMet: 1.079 ± 1.161
1.798GluAsn: 1.798 ± 0.628
3.955GluPro: 3.955 ± 1.162
1.798GluGln: 1.798 ± 0.536
4.315GluArg: 4.315 ± 0.728
3.236GluSer: 3.236 ± 1.193
2.877GluThr: 2.877 ± 0.993
2.517GluVal: 2.517 ± 0.877
0.719GluTrp: 0.719 ± 0.383
1.798GluTyr: 1.798 ± 0.628
0.0GluXaa: 0.0 ± 0.0
Phe
3.596PheAla: 3.596 ± 1.1
1.079PheCys: 1.079 ± 0.574
3.236PheAsp: 3.236 ± 0.691
5.034PheGlu: 5.034 ± 2.086
1.438PhePhe: 1.438 ± 0.47
2.517PheGly: 2.517 ± 1.072
1.798PheHis: 1.798 ± 0.628
3.236PheIle: 3.236 ± 1.826
1.079PheLys: 1.079 ± 0.461
5.394PheLeu: 5.394 ± 2.267
1.798PheMet: 1.798 ± 0.532
2.157PheAsn: 2.157 ± 0.432
1.079PhePro: 1.079 ± 0.574
1.438PheGln: 1.438 ± 1.81
1.798PheArg: 1.798 ± 0.825
3.236PheSer: 3.236 ± 0.818
3.955PheThr: 3.955 ± 1.123
1.798PheVal: 1.798 ± 0.628
0.36PheTrp: 0.36 ± 0.191
1.438PheTyr: 1.438 ± 1.426
0.0PheXaa: 0.0 ± 0.0
Gly
2.517GlyAla: 2.517 ± 0.399
1.438GlyCys: 1.438 ± 1.026
2.517GlyAsp: 2.517 ± 0.797
3.955GlyGlu: 3.955 ± 1.123
3.596GlyPhe: 3.596 ± 2.038
3.236GlyGly: 3.236 ± 1.321
0.36GlyHis: 0.36 ± 0.191
3.596GlyIle: 3.596 ± 1.023
4.315GlyLys: 4.315 ± 1.763
6.113GlyLeu: 6.113 ± 0.91
0.36GlyMet: 0.36 ± 0.191
3.236GlyAsn: 3.236 ± 1.192
2.517GlyPro: 2.517 ± 0.709
0.719GlyGln: 0.719 ± 0.627
5.394GlyArg: 5.394 ± 1.164
5.753GlySer: 5.753 ± 2.424
4.315GlyThr: 4.315 ± 2.19
4.675GlyVal: 4.675 ± 0.703
0.719GlyTrp: 0.719 ± 0.383
1.438GlyTyr: 1.438 ± 0.765
0.0GlyXaa: 0.0 ± 0.0
His
2.157HisAla: 2.157 ± 0.676
0.719HisCys: 0.719 ± 0.627
1.079HisAsp: 1.079 ± 0.615
1.438HisGlu: 1.438 ± 0.765
1.798HisPhe: 1.798 ± 0.536
1.079HisGly: 1.079 ± 0.99
0.36HisHis: 0.36 ± 0.191
2.157HisIle: 2.157 ± 0.676
1.798HisLys: 1.798 ± 0.55
3.596HisLeu: 3.596 ± 1.035
0.719HisMet: 0.719 ± 0.526
1.079HisAsn: 1.079 ± 0.461
1.438HisPro: 1.438 ± 0.47
1.079HisGln: 1.079 ± 0.99
1.438HisArg: 1.438 ± 0.765
2.517HisSer: 2.517 ± 1.083
1.438HisThr: 1.438 ± 1.254
1.079HisVal: 1.079 ± 0.922
0.36HisTrp: 0.36 ± 0.191
1.438HisTyr: 1.438 ± 0.765
0.0HisXaa: 0.0 ± 0.0
Ile
5.394IleAla: 5.394 ± 4.311
1.079IleCys: 1.079 ± 0.566
4.675IleAsp: 4.675 ± 1.5
5.394IleGlu: 5.394 ± 0.831
2.877IlePhe: 2.877 ± 0.75
2.877IleGly: 2.877 ± 0.915
1.079IleHis: 1.079 ± 0.574
4.315IleIle: 4.315 ± 0.911
2.157IleLys: 2.157 ± 1.148
5.034IleLeu: 5.034 ± 1.42
0.719IleMet: 0.719 ± 0.356
3.236IleAsn: 3.236 ± 0.818
3.236IlePro: 3.236 ± 1.522
2.877IleGln: 2.877 ± 0.75
2.877IleArg: 2.877 ± 1.527
4.675IleSer: 4.675 ± 0.703
1.438IleThr: 1.438 ± 0.679
3.236IleVal: 3.236 ± 0.862
0.0IleTrp: 0.0 ± 0.0
2.877IleTyr: 2.877 ± 1.027
0.0IleXaa: 0.0 ± 0.0
Lys
4.675LysAla: 4.675 ± 1.521
0.36LysCys: 0.36 ± 0.831
1.798LysAsp: 1.798 ± 0.536
4.315LysGlu: 4.315 ± 1.71
3.236LysPhe: 3.236 ± 1.167
3.236LysGly: 3.236 ± 1.005
0.719LysHis: 0.719 ± 0.713
3.236LysIle: 3.236 ± 0.838
5.034LysLys: 5.034 ± 1.675
6.832LysLeu: 6.832 ± 2.555
0.36LysMet: 0.36 ± 0.191
1.798LysAsn: 1.798 ± 1.684
3.596LysPro: 3.596 ± 1.014
0.36LysGln: 0.36 ± 0.191
5.034LysArg: 5.034 ± 1.517
3.955LysSer: 3.955 ± 1.968
4.675LysThr: 4.675 ± 1.895
3.236LysVal: 3.236 ± 0.896
1.079LysTrp: 1.079 ± 0.461
1.798LysTyr: 1.798 ± 0.536
0.0LysXaa: 0.0 ± 0.0
Leu
8.63LeuAla: 8.63 ± 2.566
4.675LeuCys: 4.675 ± 2.5
5.394LeuAsp: 5.394 ± 2.392
6.472LeuGlu: 6.472 ± 2.202
5.753LeuPhe: 5.753 ± 1.302
5.394LeuGly: 5.394 ± 1.073
3.955LeuHis: 3.955 ± 1.526
6.113LeuIle: 6.113 ± 1.309
8.27LeuLys: 8.27 ± 2.701
10.428LeuLeu: 10.428 ± 4.069
2.157LeuMet: 2.157 ± 1.148
2.157LeuAsn: 2.157 ± 0.945
6.472LeuPro: 6.472 ± 1.635
2.157LeuGln: 2.157 ± 0.853
5.034LeuArg: 5.034 ± 0.824
7.192LeuSer: 7.192 ± 2.107
6.113LeuThr: 6.113 ± 2.476
7.551LeuVal: 7.551 ± 2.574
0.719LeuTrp: 0.719 ± 0.383
2.517LeuTyr: 2.517 ± 1.274
0.0LeuXaa: 0.0 ± 0.0
Met
2.517MetAla: 2.517 ± 0.828
0.719MetCys: 0.719 ± 0.383
1.079MetAsp: 1.079 ± 1.099
1.079MetGlu: 1.079 ± 0.574
0.0MetPhe: 0.0 ± 0.0
1.798MetGly: 1.798 ± 0.825
1.438MetHis: 1.438 ± 0.765
1.438MetIle: 1.438 ± 0.47
0.36MetLys: 0.36 ± 0.191
1.438MetLeu: 1.438 ± 1.053
0.36MetMet: 0.36 ± 0.729
0.0MetAsn: 0.0 ± 0.0
2.157MetPro: 2.157 ± 0.928
0.36MetGln: 0.36 ± 0.191
1.438MetArg: 1.438 ± 0.47
0.36MetSer: 0.36 ± 0.191
0.719MetThr: 0.719 ± 1.288
0.719MetVal: 0.719 ± 0.526
0.0MetTrp: 0.0 ± 0.0
0.719MetTyr: 0.719 ± 0.383
0.0MetXaa: 0.0 ± 0.0
Asn
3.236AsnAla: 3.236 ± 0.905
2.157AsnCys: 2.157 ± 1.148
1.798AsnAsp: 1.798 ± 0.956
1.798AsnGlu: 1.798 ± 0.628
2.877AsnPhe: 2.877 ± 0.993
1.798AsnGly: 1.798 ± 1.455
0.36AsnHis: 0.36 ± 0.191
0.36AsnIle: 0.36 ± 0.644
2.517AsnLys: 2.517 ± 0.899
2.877AsnLeu: 2.877 ± 1.53
1.438AsnMet: 1.438 ± 1.053
1.798AsnAsn: 1.798 ± 0.55
1.798AsnPro: 1.798 ± 1.684
0.719AsnGln: 0.719 ± 0.627
2.517AsnArg: 2.517 ± 0.917
2.157AsnSer: 2.157 ± 1.24
1.798AsnThr: 1.798 ± 0.55
1.438AsnVal: 1.438 ± 0.567
1.079AsnTrp: 1.079 ± 0.669
1.438AsnTyr: 1.438 ± 0.745
0.0AsnXaa: 0.0 ± 0.0
Pro
5.034ProAla: 5.034 ± 1.902
1.438ProCys: 1.438 ± 0.765
4.315ProAsp: 4.315 ± 0.809
3.955ProGlu: 3.955 ± 0.883
0.36ProPhe: 0.36 ± 0.191
3.236ProGly: 3.236 ± 1.283
2.157ProHis: 2.157 ± 1.48
3.236ProIle: 3.236 ± 1.676
1.079ProLys: 1.079 ± 0.704
4.675ProLeu: 4.675 ± 2.444
0.719ProMet: 0.719 ± 0.73
1.079ProAsn: 1.079 ± 0.922
4.315ProPro: 4.315 ± 2.951
1.079ProGln: 1.079 ± 0.574
3.236ProArg: 3.236 ± 1.573
3.236ProSer: 3.236 ± 0.702
2.877ProThr: 2.877 ± 1.358
2.517ProVal: 2.517 ± 0.828
0.36ProTrp: 0.36 ± 0.191
2.517ProTyr: 2.517 ± 0.828
0.0ProXaa: 0.0 ± 0.0
Gln
2.517GlnAla: 2.517 ± 2.388
1.438GlnCys: 1.438 ± 0.885
0.36GlnAsp: 0.36 ± 0.191
0.36GlnGlu: 0.36 ± 0.191
1.079GlnPhe: 1.079 ± 0.574
0.36GlnGly: 0.36 ± 0.191
0.36GlnHis: 0.36 ± 0.772
1.438GlnIle: 1.438 ± 0.567
1.079GlnLys: 1.079 ± 0.461
3.955GlnLeu: 3.955 ± 1.355
0.0GlnMet: 0.0 ± 0.0
1.079GlnAsn: 1.079 ± 0.461
2.517GlnPro: 2.517 ± 0.911
0.36GlnGln: 0.36 ± 0.191
1.438GlnArg: 1.438 ± 0.885
2.517GlnSer: 2.517 ± 0.873
1.438GlnThr: 1.438 ± 0.567
0.36GlnVal: 0.36 ± 0.772
0.36GlnTrp: 0.36 ± 0.785
0.719GlnTyr: 0.719 ± 0.627
0.0GlnXaa: 0.0 ± 0.0
Arg
5.034ArgAla: 5.034 ± 1.51
2.157ArgCys: 2.157 ± 1.665
3.596ArgAsp: 3.596 ± 2.093
2.517ArgGlu: 2.517 ± 1.117
3.955ArgPhe: 3.955 ± 0.883
3.236ArgGly: 3.236 ± 0.632
3.236ArgHis: 3.236 ± 1.076
2.517ArgIle: 2.517 ± 0.828
3.236ArgLys: 3.236 ± 1.749
6.472ArgLeu: 6.472 ± 1.507
1.798ArgMet: 1.798 ± 0.706
1.438ArgAsn: 1.438 ± 0.765
1.438ArgPro: 1.438 ± 1.422
1.079ArgGln: 1.079 ± 1.161
3.236ArgArg: 3.236 ± 1.026
4.315ArgSer: 4.315 ± 0.998
4.675ArgThr: 4.675 ± 1.926
2.157ArgVal: 2.157 ± 1.946
1.079ArgTrp: 1.079 ± 0.574
2.517ArgTyr: 2.517 ± 0.828
0.0ArgXaa: 0.0 ± 0.0
Ser
5.034SerAla: 5.034 ± 0.926
1.798SerCys: 1.798 ± 0.829
3.236SerAsp: 3.236 ± 0.896
3.955SerGlu: 3.955 ± 1.218
3.236SerPhe: 3.236 ± 0.568
3.596SerGly: 3.596 ± 1.239
0.719SerHis: 0.719 ± 0.383
2.517SerIle: 2.517 ± 0.652
7.551SerLys: 7.551 ± 1.867
6.832SerLeu: 6.832 ± 3.251
1.079SerMet: 1.079 ± 0.461
2.877SerAsn: 2.877 ± 1.225
4.675SerPro: 4.675 ± 0.993
2.517SerGln: 2.517 ± 0.884
3.955SerArg: 3.955 ± 1.526
6.472SerSer: 6.472 ± 1.199
3.955SerThr: 3.955 ± 1.305
3.596SerVal: 3.596 ± 0.971
0.0SerTrp: 0.0 ± 0.0
2.517SerTyr: 2.517 ± 1.212
0.0SerXaa: 0.0 ± 0.0
Thr
3.955ThrAla: 3.955 ± 0.582
0.36ThrCys: 0.36 ± 0.831
2.157ThrAsp: 2.157 ± 0.922
4.315ThrGlu: 4.315 ± 1.258
4.315ThrPhe: 4.315 ± 1.472
5.034ThrGly: 5.034 ± 0.971
2.877ThrHis: 2.877 ± 0.969
4.315ThrIle: 4.315 ± 0.626
2.877ThrLys: 2.877 ± 1.206
6.472ThrLeu: 6.472 ± 2.76
1.438ThrMet: 1.438 ± 0.765
2.517ThrAsn: 2.517 ± 0.828
3.236ThrPro: 3.236 ± 1.372
0.719ThrGln: 0.719 ± 0.383
2.517ThrArg: 2.517 ± 1.409
4.315ThrSer: 4.315 ± 1.224
2.157ThrThr: 2.157 ± 1.182
3.596ThrVal: 3.596 ± 1.301
0.0ThrTrp: 0.0 ± 0.0
3.236ThrTyr: 3.236 ± 1.456
0.0ThrXaa: 0.0 ± 0.0
Val
3.955ValAla: 3.955 ± 2.041
1.079ValCys: 1.079 ± 0.574
3.236ValAsp: 3.236 ± 1.181
1.079ValGlu: 1.079 ± 0.566
2.517ValPhe: 2.517 ± 0.709
6.472ValGly: 6.472 ± 2.391
2.157ValHis: 2.157 ± 0.676
3.236ValIle: 3.236 ± 1.055
2.517ValLys: 2.517 ± 0.399
5.394ValLeu: 5.394 ± 1.45
0.36ValMet: 0.36 ± 0.191
0.719ValAsn: 0.719 ± 0.383
1.438ValPro: 1.438 ± 0.679
0.36ValGln: 0.36 ± 0.644
3.955ValArg: 3.955 ± 0.647
5.034ValSer: 5.034 ± 1.216
5.394ValThr: 5.394 ± 0.649
2.157ValVal: 2.157 ± 1.567
0.36ValTrp: 0.36 ± 0.772
1.438ValTyr: 1.438 ± 0.66
0.0ValXaa: 0.0 ± 0.0
Trp
1.438TrpAla: 1.438 ± 0.745
0.719TrpCys: 0.719 ± 0.383
0.36TrpAsp: 0.36 ± 0.191
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.36TrpGly: 0.36 ± 0.644
0.36TrpHis: 0.36 ± 0.191
0.719TrpIle: 0.719 ± 0.679
0.0TrpLys: 0.0 ± 0.0
1.079TrpLeu: 1.079 ± 0.574
0.0TrpMet: 0.0 ± 0.0
0.36TrpAsn: 0.36 ± 0.644
0.36TrpPro: 0.36 ± 0.191
0.36TrpGln: 0.36 ± 0.644
0.719TrpArg: 0.719 ± 1.661
0.719TrpSer: 0.719 ± 0.383
0.0TrpThr: 0.0 ± 0.0
1.438TrpVal: 1.438 ± 0.765
0.0TrpTrp: 0.0 ± 0.0
0.719TrpTyr: 0.719 ± 0.383
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.675TyrAla: 4.675 ± 1.106
1.079TyrCys: 1.079 ± 0.704
0.719TyrAsp: 0.719 ± 0.383
2.877TyrGlu: 2.877 ± 1.426
0.36TyrPhe: 0.36 ± 0.191
2.517TyrGly: 2.517 ± 1.117
0.0TyrHis: 0.0 ± 0.0
2.517TyrIle: 2.517 ± 1.353
2.877TyrLys: 2.877 ± 1.53
4.315TyrLeu: 4.315 ± 0.693
0.36TyrMet: 0.36 ± 0.191
1.079TyrAsn: 1.079 ± 0.669
1.079TyrPro: 1.079 ± 0.574
0.719TyrGln: 0.719 ± 0.383
1.798TyrArg: 1.798 ± 0.829
2.157TyrSer: 2.157 ± 0.711
2.157TyrThr: 2.157 ± 0.782
2.517TyrVal: 2.517 ± 0.828
0.36TyrTrp: 0.36 ± 0.191
0.719TyrTyr: 0.719 ± 0.526
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2782 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski