Amino acid dipepetide frequency for Marinilabilia salmonicolor

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.699AlaAla: 4.699 ± 0.073	0.541AlaCys: 0.541 ± 0.02	3.784AlaAsp: 3.784 ± 0.05	4.254AlaGlu: 4.254 ± 0.059	3.453AlaPhe: 3.453 ± 0.051	5.393AlaGly: 5.393 ± 0.074	1.18AlaHis: 1.18 ± 0.031	4.507AlaIle: 4.507 ± 0.065	3.326AlaLys: 3.326 ± 0.061	6.29AlaLeu: 6.29 ± 0.066	1.62AlaMet: 1.62 ± 0.04	2.913AlaAsn: 2.913 ± 0.047	2.225AlaPro: 2.225 ± 0.045	2.188AlaGln: 2.188 ± 0.039	3.169AlaArg: 3.169 ± 0.059	4.207AlaSer: 4.207 ± 0.057	3.319AlaThr: 3.319 ± 0.062	4.325AlaVal: 4.325 ± 0.066	0.804AlaTrp: 0.804 ± 0.023	2.211AlaTyr: 2.211 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.389CysAla: 0.389 ± 0.016	0.102CysCys: 0.102 ± 0.009	0.454CysAsp: 0.454 ± 0.017	0.486CysGlu: 0.486 ± 0.021	0.369CysPhe: 0.369 ± 0.016	0.617CysGly: 0.617 ± 0.024	0.209CysHis: 0.209 ± 0.013	0.445CysIle: 0.445 ± 0.018	0.404CysLys: 0.404 ± 0.017	0.602CysLeu: 0.602 ± 0.019	0.153CysMet: 0.153 ± 0.01	0.414CysAsn: 0.414 ± 0.017	0.376CysPro: 0.376 ± 0.021	0.238CysGln: 0.238 ± 0.013	0.395CysArg: 0.395 ± 0.017	0.51CysSer: 0.51 ± 0.024	0.409CysThr: 0.409 ± 0.019	0.408CysVal: 0.408 ± 0.018	0.09CysTrp: 0.09 ± 0.007	0.279CysTyr: 0.279 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.712AspAla: 3.712 ± 0.058	0.392AspCys: 0.392 ± 0.017	3.182AspAsp: 3.182 ± 0.071	4.319AspGlu: 4.319 ± 0.058	3.562AspPhe: 3.562 ± 0.048	4.161AspGly: 4.161 ± 0.081	1.084AspHis: 1.084 ± 0.028	4.043AspIle: 4.043 ± 0.054	3.457AspLys: 3.457 ± 0.052	5.279AspLeu: 5.279 ± 0.057	1.331AspMet: 1.331 ± 0.03	2.932AspAsn: 2.932 ± 0.054	2.159AspPro: 2.159 ± 0.045	1.904AspGln: 1.904 ± 0.04	2.41AspArg: 2.41 ± 0.046	3.269AspSer: 3.269 ± 0.058	2.423AspThr: 2.423 ± 0.047	3.876AspVal: 3.876 ± 0.059	0.869AspTrp: 0.869 ± 0.024	2.832AspTyr: 2.832 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	4.719GluAla: 4.719 ± 0.08	0.374GluCys: 0.374 ± 0.017	3.835GluAsp: 3.835 ± 0.053	5.847GluGlu: 5.847 ± 0.08	2.853GluPhe: 2.853 ± 0.043	4.398GluGly: 4.398 ± 0.067	1.261GluHis: 1.261 ± 0.032	5.351GluIle: 5.351 ± 0.067	5.947GluLys: 5.947 ± 0.08	6.422GluLeu: 6.422 ± 0.066	2.125GluMet: 2.125 ± 0.038	4.391GluAsn: 4.391 ± 0.053	2.05GluPro: 2.05 ± 0.032	2.652GluGln: 2.652 ± 0.048	2.997GluArg: 2.997 ± 0.052	3.807GluSer: 3.807 ± 0.053	3.73GluThr: 3.73 ± 0.055	4.913GluVal: 4.913 ± 0.058	0.865GluTrp: 0.865 ± 0.026	2.563GluTyr: 2.563 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	2.964PheAla: 2.964 ± 0.051	0.431PheCys: 0.431 ± 0.019	3.297PheAsp: 3.297 ± 0.054	3.409PheGlu: 3.409 ± 0.059	3.052PhePhe: 3.052 ± 0.057	3.561PheGly: 3.561 ± 0.056	0.999PheHis: 0.999 ± 0.03	3.331PheIle: 3.331 ± 0.056	2.838PheLys: 2.838 ± 0.046	4.891PheLeu: 4.891 ± 0.071	1.229PheMet: 1.229 ± 0.029	2.865PheAsn: 2.865 ± 0.042	1.912PhePro: 1.912 ± 0.038	1.506PheGln: 1.506 ± 0.034	2.334PheArg: 2.334 ± 0.043	4.424PheSer: 4.424 ± 0.056	2.687PheThr: 2.687 ± 0.046	3.148PheVal: 3.148 ± 0.05	0.665PheTrp: 0.665 ± 0.023	2.109PheTyr: 2.109 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.501GlyAla: 4.501 ± 0.066	0.672GlyCys: 0.672 ± 0.029	3.879GlyAsp: 3.879 ± 0.066	4.557GlyGlu: 4.557 ± 0.071	3.843GlyPhe: 3.843 ± 0.055	5.052GlyGly: 5.052 ± 0.09	1.367GlyHis: 1.367 ± 0.032	5.451GlyIle: 5.451 ± 0.07	4.693GlyLys: 4.693 ± 0.065	6.442GlyLeu: 6.442 ± 0.067	1.923GlyMet: 1.923 ± 0.042	3.848GlyAsn: 3.848 ± 0.065	1.746GlyPro: 1.746 ± 0.038	2.264GlyGln: 2.264 ± 0.039	2.966GlyArg: 2.966 ± 0.046	4.227GlySer: 4.227 ± 0.073	4.144GlyThr: 4.144 ± 0.082	4.823GlyVal: 4.823 ± 0.067	1.022GlyTrp: 1.022 ± 0.032	2.937GlyTyr: 2.937 ± 0.055	0.0GlyXaa: 0.0 ± 0.0
His	1.062HisAla: 1.062 ± 0.029	0.203HisCys: 0.203 ± 0.011	0.949HisAsp: 0.949 ± 0.026	1.183HisGlu: 1.183 ± 0.031	1.254HisPhe: 1.254 ± 0.032	1.216HisGly: 1.216 ± 0.033	0.6HisHis: 0.6 ± 0.024	1.393HisIle: 1.393 ± 0.031	1.164HisLys: 1.164 ± 0.029	2.037HisLeu: 2.037 ± 0.045	0.324HisMet: 0.324 ± 0.015	0.992HisAsn: 0.992 ± 0.028	1.162HisPro: 1.162 ± 0.032	0.848HisGln: 0.848 ± 0.027	0.92HisArg: 0.92 ± 0.028	1.209HisSer: 1.209 ± 0.03	0.954HisThr: 0.954 ± 0.027	0.93HisVal: 0.93 ± 0.022	0.268HisTrp: 0.268 ± 0.015	0.863HisTyr: 0.863 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	4.65IleAla: 4.65 ± 0.063	0.518IleCys: 0.518 ± 0.021	4.4IleAsp: 4.4 ± 0.054	5.07IleGlu: 5.07 ± 0.067	3.258IlePhe: 3.258 ± 0.053	4.569IleGly: 4.569 ± 0.066	1.392IleHis: 1.392 ± 0.032	4.803IleIle: 4.803 ± 0.08	4.307IleLys: 4.307 ± 0.065	6.125IleLeu: 6.125 ± 0.079	1.375IleMet: 1.375 ± 0.035	3.857IleAsn: 3.857 ± 0.051	3.239IlePro: 3.239 ± 0.049	2.178IleGln: 2.178 ± 0.036	3.335IleArg: 3.335 ± 0.051	5.321IleSer: 5.321 ± 0.073	4.0IleThr: 4.0 ± 0.074	4.305IleVal: 4.305 ± 0.061	0.759IleTrp: 0.759 ± 0.027	2.484IleTyr: 2.484 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.333LysAla: 4.333 ± 0.064	0.365LysCys: 0.365 ± 0.017	3.468LysAsp: 3.468 ± 0.06	5.559LysGlu: 5.559 ± 0.081	2.34LysPhe: 2.34 ± 0.043	4.189LysGly: 4.189 ± 0.059	1.24LysHis: 1.24 ± 0.028	4.606LysIle: 4.606 ± 0.065	5.154LysLys: 5.154 ± 0.078	5.177LysLeu: 5.177 ± 0.078	1.923LysMet: 1.923 ± 0.036	3.774LysAsn: 3.774 ± 0.063	2.283LysPro: 2.283 ± 0.043	2.244LysGln: 2.244 ± 0.044	2.886LysArg: 2.886 ± 0.052	3.801LysSer: 3.801 ± 0.057	3.651LysThr: 3.651 ± 0.055	4.178LysVal: 4.178 ± 0.061	0.775LysTrp: 0.775 ± 0.023	2.543LysTyr: 2.543 ± 0.049	0.0LysXaa: 0.0 ± 0.0
Leu	5.89LeuAla: 5.89 ± 0.077	0.615LeuCys: 0.615 ± 0.021	4.766LeuAsp: 4.766 ± 0.061	6.029LeuGlu: 6.029 ± 0.066	5.108LeuPhe: 5.108 ± 0.073	5.587LeuGly: 5.587 ± 0.072	1.668LeuHis: 1.668 ± 0.034	6.317LeuIle: 6.317 ± 0.078	7.112LeuLys: 7.112 ± 0.092	8.903LeuLeu: 8.903 ± 0.109	2.465LeuMet: 2.465 ± 0.041	5.211LeuAsn: 5.211 ± 0.063	3.925LeuPro: 3.925 ± 0.051	3.153LeuGln: 3.153 ± 0.05	3.932LeuArg: 3.932 ± 0.059	6.888LeuSer: 6.888 ± 0.081	5.092LeuThr: 5.092 ± 0.057	5.349LeuVal: 5.349 ± 0.075	1.087LeuTrp: 1.087 ± 0.032	3.021LeuTyr: 3.021 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.036MetAla: 2.036 ± 0.041	0.129MetCys: 0.129 ± 0.009	1.441MetAsp: 1.441 ± 0.033	1.824MetGlu: 1.824 ± 0.035	0.975MetPhe: 0.975 ± 0.024	1.849MetGly: 1.849 ± 0.037	0.474MetHis: 0.474 ± 0.017	1.521MetIle: 1.521 ± 0.035	1.936MetLys: 1.936 ± 0.039	2.21MetLeu: 2.21 ± 0.041	0.699MetMet: 0.699 ± 0.024	1.31MetAsn: 1.31 ± 0.034	1.086MetPro: 1.086 ± 0.029	0.958MetGln: 0.958 ± 0.025	1.113MetArg: 1.113 ± 0.03	1.504MetSer: 1.504 ± 0.03	1.26MetThr: 1.26 ± 0.032	1.802MetVal: 1.802 ± 0.042	0.231MetTrp: 0.231 ± 0.012	0.6MetTyr: 0.6 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.265AsnAla: 3.265 ± 0.051	0.41AsnCys: 0.41 ± 0.019	2.853AsnAsp: 2.853 ± 0.055	3.362AsnGlu: 3.362 ± 0.048	2.503AsnPhe: 2.503 ± 0.049	3.795AsnGly: 3.795 ± 0.074	1.198AsnHis: 1.198 ± 0.03	4.141AsnIle: 4.141 ± 0.055	3.224AsnLys: 3.224 ± 0.059	4.996AsnLeu: 4.996 ± 0.064	1.223AsnMet: 1.223 ± 0.03	3.106AsnAsn: 3.106 ± 0.052	2.785AsnPro: 2.785 ± 0.049	2.189AsnGln: 2.189 ± 0.045	2.551AsnArg: 2.551 ± 0.046	3.354AsnSer: 3.354 ± 0.055	2.861AsnThr: 2.861 ± 0.058	3.177AsnVal: 3.177 ± 0.054	0.748AsnTrp: 0.748 ± 0.025	2.33AsnTyr: 2.33 ± 0.048	0.0AsnXaa: 0.0 ± 0.0
Pro	2.735ProAla: 2.735 ± 0.051	0.232ProCys: 0.232 ± 0.012	3.021ProAsp: 3.021 ± 0.054	3.94ProGlu: 3.94 ± 0.06	2.084ProPhe: 2.084 ± 0.041	3.226ProGly: 3.226 ± 0.053	0.772ProHis: 0.772 ± 0.027	1.98ProIle: 1.98 ± 0.036	1.807ProLys: 1.807 ± 0.036	3.387ProLeu: 3.387 ± 0.049	0.875ProMet: 0.875 ± 0.028	1.583ProAsn: 1.583 ± 0.032	1.11ProPro: 1.11 ± 0.031	1.325ProGln: 1.325 ± 0.033	1.392ProArg: 1.392 ± 0.037	2.3ProSer: 2.3 ± 0.04	1.648ProThr: 1.648 ± 0.039	3.555ProVal: 3.555 ± 0.057	0.5ProTrp: 0.5 ± 0.019	1.387ProTyr: 1.387 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	2.099GlnAla: 2.099 ± 0.041	0.187GlnCys: 0.187 ± 0.013	1.599GlnAsp: 1.599 ± 0.029	2.456GlnGlu: 2.456 ± 0.045	1.482GlnPhe: 1.482 ± 0.032	2.0GlnGly: 2.0 ± 0.035	0.634GlnHis: 0.634 ± 0.023	2.511GlnIle: 2.511 ± 0.04	2.765GlnLys: 2.765 ± 0.054	3.226GlnLeu: 3.226 ± 0.053	1.099GlnMet: 1.099 ± 0.031	2.076GlnAsn: 2.076 ± 0.041	1.298GlnPro: 1.298 ± 0.03	1.5GlnGln: 1.5 ± 0.042	1.555GlnArg: 1.555 ± 0.036	2.064GlnSer: 2.064 ± 0.042	1.95GlnThr: 1.95 ± 0.042	2.124GlnVal: 2.124 ± 0.038	0.453GlnTrp: 0.453 ± 0.019	1.358GlnTyr: 1.358 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.446ArgAla: 2.446 ± 0.045	0.292ArgCys: 0.292 ± 0.015	2.374ArgAsp: 2.374 ± 0.043	3.371ArgGlu: 3.371 ± 0.055	2.514ArgPhe: 2.514 ± 0.045	2.568ArgGly: 2.568 ± 0.042	0.893ArgHis: 0.893 ± 0.025	3.491ArgIle: 3.491 ± 0.055	3.415ArgLys: 3.415 ± 0.06	4.298ArgLeu: 4.298 ± 0.053	1.23ArgMet: 1.23 ± 0.034	2.656ArgAsn: 2.656 ± 0.039	1.521ArgPro: 1.521 ± 0.036	1.74ArgGln: 1.74 ± 0.032	2.012ArgArg: 2.012 ± 0.044	2.308ArgSer: 2.308 ± 0.043	2.143ArgThr: 2.143 ± 0.036	2.694ArgVal: 2.694 ± 0.043	0.646ArgTrp: 0.646 ± 0.023	1.959ArgTyr: 1.959 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	4.117SerAla: 4.117 ± 0.056	0.568SerCys: 0.568 ± 0.02	3.899SerAsp: 3.899 ± 0.064	4.394SerGlu: 4.394 ± 0.054	3.787SerPhe: 3.787 ± 0.052	5.804SerGly: 5.804 ± 0.081	1.243SerHis: 1.243 ± 0.027	4.248SerIle: 4.248 ± 0.062	3.446SerLys: 3.446 ± 0.058	6.206SerLeu: 6.206 ± 0.06	1.489SerMet: 1.489 ± 0.032	3.095SerAsn: 3.095 ± 0.052	2.619SerPro: 2.619 ± 0.05	2.054SerGln: 2.054 ± 0.036	2.928SerArg: 2.928 ± 0.049	4.438SerSer: 4.438 ± 0.072	3.168SerThr: 3.168 ± 0.052	4.642SerVal: 4.642 ± 0.068	0.887SerTrp: 0.887 ± 0.023	2.466SerTyr: 2.466 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	3.531ThrAla: 3.531 ± 0.06	0.317ThrCys: 0.317 ± 0.019	3.171ThrAsp: 3.171 ± 0.058	3.362ThrGlu: 3.362 ± 0.053	2.692ThrPhe: 2.692 ± 0.045	4.781ThrGly: 4.781 ± 0.071	0.997ThrHis: 0.997 ± 0.029	4.166ThrIle: 4.166 ± 0.074	2.562ThrLys: 2.562 ± 0.041	4.789ThrLeu: 4.789 ± 0.063	1.046ThrMet: 1.046 ± 0.027	2.637ThrAsn: 2.637 ± 0.059	2.631ThrPro: 2.631 ± 0.063	1.527ThrGln: 1.527 ± 0.03	2.211ThrArg: 2.211 ± 0.037	3.493ThrSer: 3.493 ± 0.054	2.993ThrThr: 2.993 ± 0.059	3.443ThrVal: 3.443 ± 0.084	0.629ThrTrp: 0.629 ± 0.023	1.886ThrTyr: 1.886 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	4.385ValAla: 4.385 ± 0.066	0.532ValCys: 0.532 ± 0.021	3.837ValAsp: 3.837 ± 0.059	4.465ValGlu: 4.465 ± 0.056	3.673ValPhe: 3.673 ± 0.055	3.896ValGly: 3.896 ± 0.057	1.131ValHis: 1.131 ± 0.033	4.507ValIle: 4.507 ± 0.056	4.058ValLys: 4.058 ± 0.058	6.033ValLeu: 6.033 ± 0.075	1.611ValMet: 1.611 ± 0.035	3.447ValAsn: 3.447 ± 0.058	2.739ValPro: 2.739 ± 0.046	1.849ValGln: 1.849 ± 0.038	2.816ValArg: 2.816 ± 0.04	4.736ValSer: 4.736 ± 0.071	3.789ValThr: 3.789 ± 0.099	4.976ValVal: 4.976 ± 0.072	0.757ValTrp: 0.757 ± 0.025	2.266ValTyr: 2.266 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.732TrpAla: 0.732 ± 0.02	0.11TrpCys: 0.11 ± 0.009	0.722TrpAsp: 0.722 ± 0.025	0.867TrpGlu: 0.867 ± 0.025	0.711TrpPhe: 0.711 ± 0.021	0.98TrpGly: 0.98 ± 0.03	0.287TrpHis: 0.287 ± 0.014	0.844TrpIle: 0.844 ± 0.028	0.721TrpLys: 0.721 ± 0.022	1.183TrpLeu: 1.183 ± 0.037	0.408TrpMet: 0.408 ± 0.019	0.72TrpAsn: 0.72 ± 0.024	0.402TrpPro: 0.402 ± 0.02	0.545TrpGln: 0.545 ± 0.02	0.61TrpArg: 0.61 ± 0.02	0.821TrpSer: 0.821 ± 0.028	0.662TrpThr: 0.662 ± 0.027	0.778TrpVal: 0.778 ± 0.025	0.205TrpTrp: 0.205 ± 0.013	0.475TrpTyr: 0.475 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.143TyrAla: 2.143 ± 0.043	0.359TyrCys: 0.359 ± 0.017	2.265TyrAsp: 2.265 ± 0.047	2.342TyrGlu: 2.342 ± 0.046	2.139TyrPhe: 2.139 ± 0.044	2.715TyrGly: 2.715 ± 0.054	0.904TyrHis: 0.904 ± 0.025	2.288TyrIle: 2.288 ± 0.042	2.149TyrLys: 2.149 ± 0.038	3.625TyrLeu: 3.625 ± 0.056	0.813TyrMet: 0.813 ± 0.026	2.244TyrAsn: 2.244 ± 0.04	1.593TyrPro: 1.593 ± 0.03	1.578TyrGln: 1.578 ± 0.033	2.037TyrArg: 2.037 ± 0.039	2.816TyrSer: 2.816 ± 0.042	1.979TyrThr: 1.979 ± 0.051	2.058TyrVal: 2.058 ± 0.047	0.524TyrTrp: 0.524 ± 0.021	1.745TyrTyr: 1.745 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4084 proteins (1474478 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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