Amino acid dipepetide frequency for Canna yellow mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.897AlaAla: 4.897 ± 5.617
1.469AlaCys: 1.469 ± 0.705
2.938AlaAsp: 2.938 ± 1.41
6.856AlaGlu: 6.856 ± 3.291
2.449AlaPhe: 2.449 ± 1.175
2.938AlaGly: 2.938 ± 1.733
0.49AlaHis: 0.49 ± 1.743
4.407AlaIle: 4.407 ± 2.296
4.407AlaLys: 4.407 ± 2.87
12.243AlaLeu: 12.243 ± 0.671
2.449AlaMet: 2.449 ± 0.871
4.407AlaAsn: 4.407 ± 2.78
1.469AlaPro: 1.469 ± 1.435
2.449AlaGln: 2.449 ± 1.175
5.387AlaArg: 5.387 ± 1.694
4.897AlaSer: 4.897 ± 2.528
2.938AlaThr: 2.938 ± 2.869
3.918AlaVal: 3.918 ± 1.272
0.49AlaTrp: 0.49 ± 0.235
3.428AlaTyr: 3.428 ± 1.645
0.0AlaXaa: 0.0 ± 0.0
Cys
0.49CysAla: 0.49 ± 0.235
0.49CysCys: 0.49 ± 0.235
0.0CysAsp: 0.0 ± 0.0
0.49CysGlu: 0.49 ± 0.235
0.49CysPhe: 0.49 ± 0.235
1.959CysGly: 1.959 ± 0.94
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.959CysLys: 1.959 ± 0.94
1.469CysLeu: 1.469 ± 0.705
0.49CysMet: 0.49 ± 0.235
0.979CysAsn: 0.979 ± 0.47
0.49CysPro: 0.49 ± 0.235
0.49CysGln: 0.49 ± 0.235
1.469CysArg: 1.469 ± 0.705
1.469CysSer: 1.469 ± 1.374
0.0CysThr: 0.0 ± 0.0
0.49CysVal: 0.49 ± 0.235
0.0CysTrp: 0.0 ± 0.0
1.469CysTyr: 1.469 ± 1.374
0.0CysXaa: 0.0 ± 0.0
Asp
2.938AspAla: 2.938 ± 1.41
1.959AspCys: 1.959 ± 0.94
4.407AspAsp: 4.407 ± 1.416
3.428AspGlu: 3.428 ± 1.645
2.449AspPhe: 2.449 ± 1.175
3.918AspGly: 3.918 ± 1.881
0.0AspHis: 0.0 ± 0.0
1.959AspIle: 1.959 ± 0.94
4.407AspLys: 4.407 ± 2.586
6.856AspLeu: 6.856 ± 5.546
2.449AspMet: 2.449 ± 1.101
1.469AspAsn: 1.469 ± 1.374
2.449AspPro: 2.449 ± 1.175
1.959AspGln: 1.959 ± 0.94
1.959AspArg: 1.959 ± 0.94
1.959AspSer: 1.959 ± 0.94
3.918AspThr: 3.918 ± 2.663
3.918AspVal: 3.918 ± 2.433
0.979AspTrp: 0.979 ± 1.566
2.938AspTyr: 2.938 ± 0.998
0.0AspXaa: 0.0 ± 0.0
Glu
13.222GluAla: 13.222 ± 7.869
0.0GluCys: 0.0 ± 0.0
7.346GluAsp: 7.346 ± 1.919
12.733GluGlu: 12.733 ± 4.523
2.449GluPhe: 2.449 ± 1.175
3.918GluGly: 3.918 ± 0.976
1.959GluHis: 1.959 ± 0.94
6.366GluIle: 6.366 ± 1.667
5.877GluLys: 5.877 ± 1.48
5.877GluLeu: 5.877 ± 3.65
1.469GluMet: 1.469 ± 0.705
2.449GluAsn: 2.449 ± 1.087
1.959GluPro: 1.959 ± 1.331
4.407GluGln: 4.407 ± 2.296
4.897GluArg: 4.897 ± 1.162
3.428GluSer: 3.428 ± 1.645
2.938GluThr: 2.938 ± 1.41
6.366GluVal: 6.366 ± 2.131
1.469GluTrp: 1.469 ± 0.705
2.938GluTyr: 2.938 ± 0.998
0.0GluXaa: 0.0 ± 0.0
Phe
1.469PheAla: 1.469 ± 0.705
0.49PheCys: 0.49 ± 0.235
1.469PheAsp: 1.469 ± 0.705
1.469PheGlu: 1.469 ± 0.705
0.49PhePhe: 0.49 ± 0.235
1.469PheGly: 1.469 ± 0.705
0.979PheHis: 0.979 ± 0.47
3.428PheIle: 3.428 ± 0.958
1.469PheLys: 1.469 ± 0.705
4.897PheLeu: 4.897 ± 1.544
0.0PheMet: 0.0 ± 0.0
0.979PheAsn: 0.979 ± 0.47
1.959PhePro: 1.959 ± 0.94
2.938PheGln: 2.938 ± 1.41
1.959PheArg: 1.959 ± 0.94
1.469PheSer: 1.469 ± 0.705
1.959PheThr: 1.959 ± 1.331
0.0PheVal: 0.0 ± 0.0
0.979PheTrp: 0.979 ± 1.552
1.959PheTyr: 1.959 ± 0.94
0.0PheXaa: 0.0 ± 0.0
Gly
1.959GlyAla: 1.959 ± 0.94
1.469GlyCys: 1.469 ± 0.705
1.469GlyAsp: 1.469 ± 0.705
6.366GlyGlu: 6.366 ± 2.044
2.938GlyPhe: 2.938 ± 1.239
4.897GlyGly: 4.897 ± 0.82
0.49GlyHis: 0.49 ± 0.235
2.938GlyIle: 2.938 ± 1.41
3.428GlyLys: 3.428 ± 1.645
5.877GlyLeu: 5.877 ± 1.48
0.979GlyMet: 0.979 ± 0.47
2.938GlyAsn: 2.938 ± 1.733
1.469GlyPro: 1.469 ± 0.705
1.959GlyGln: 1.959 ± 1.217
3.918GlyArg: 3.918 ± 1.881
0.49GlySer: 0.49 ± 0.235
3.428GlyThr: 3.428 ± 1.257
3.428GlyVal: 3.428 ± 1.645
0.49GlyTrp: 0.49 ± 0.235
3.918GlyTyr: 3.918 ± 0.976
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.49HisCys: 0.49 ± 0.235
0.49HisAsp: 0.49 ± 0.235
0.979HisGlu: 0.979 ± 0.47
0.49HisPhe: 0.49 ± 0.235
0.0HisGly: 0.0 ± 0.0
0.979HisHis: 0.979 ± 0.47
3.918HisIle: 3.918 ± 1.272
0.979HisLys: 0.979 ± 0.47
1.959HisLeu: 1.959 ± 0.94
0.0HisMet: 0.0 ± 0.0
0.49HisAsn: 0.49 ± 1.743
0.0HisPro: 0.0 ± 0.0
0.49HisGln: 0.49 ± 0.235
2.938HisArg: 2.938 ± 2.749
0.0HisSer: 0.0 ± 0.0
0.979HisThr: 0.979 ± 1.552
1.469HisVal: 1.469 ± 0.705
0.49HisTrp: 0.49 ± 0.235
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.407IleAla: 4.407 ± 1.416
1.469IleCys: 1.469 ± 0.705
4.897IleAsp: 4.897 ± 2.351
5.877IleGlu: 5.877 ± 2.103
0.979IlePhe: 0.979 ± 0.47
6.366IleGly: 6.366 ± 0.289
0.979IleHis: 0.979 ± 3.486
4.407IleIle: 4.407 ± 2.116
6.366IleLys: 6.366 ± 1.942
4.407IleLeu: 4.407 ± 1.044
1.469IleMet: 1.469 ± 0.705
2.938IleAsn: 2.938 ± 1.41
3.918IlePro: 3.918 ± 0.976
2.938IleGln: 2.938 ± 0.998
4.897IleArg: 4.897 ± 1.544
2.449IleSer: 2.449 ± 3.701
4.407IleThr: 4.407 ± 1.416
3.428IleVal: 3.428 ± 0.958
0.49IleTrp: 0.49 ± 0.235
1.959IleTyr: 1.959 ± 0.94
0.0IleXaa: 0.0 ± 0.0
Lys
5.387LysAla: 5.387 ± 1.31
2.449LysCys: 2.449 ± 1.175
2.938LysAsp: 2.938 ± 2.749
6.856LysGlu: 6.856 ± 4.659
2.449LysPhe: 2.449 ± 1.087
5.387LysGly: 5.387 ± 2.586
2.938LysHis: 2.938 ± 1.41
7.346LysIle: 7.346 ± 2.773
5.387LysLys: 5.387 ± 1.31
5.387LysLeu: 5.387 ± 3.699
1.959LysMet: 1.959 ± 0.94
5.387LysAsn: 5.387 ± 2.327
3.428LysPro: 3.428 ± 0.958
2.938LysGln: 2.938 ± 1.733
1.959LysArg: 1.959 ± 0.94
3.918LysSer: 3.918 ± 1.272
2.938LysThr: 2.938 ± 1.41
5.387LysVal: 5.387 ± 5.362
0.49LysTrp: 0.49 ± 0.235
0.979LysTyr: 0.979 ± 0.47
0.0LysXaa: 0.0 ± 0.0
Leu
8.815LeuAla: 8.815 ± 5.56
1.469LeuCys: 1.469 ± 1.374
6.366LeuAsp: 6.366 ± 6.363
13.712LeuGlu: 13.712 ± 1.635
1.469LeuPhe: 1.469 ± 1.435
4.897LeuGly: 4.897 ± 1.162
1.959LeuHis: 1.959 ± 2.199
3.918LeuIle: 3.918 ± 4.295
8.325LeuLys: 8.325 ± 1.618
6.366LeuLeu: 6.366 ± 3.235
0.979LeuMet: 0.979 ± 0.47
4.407LeuAsn: 4.407 ± 1.416
2.449LeuPro: 2.449 ± 1.175
2.938LeuGln: 2.938 ± 2.749
5.387LeuArg: 5.387 ± 2.327
7.346LeuSer: 7.346 ± 3.396
3.428LeuThr: 3.428 ± 1.645
7.346LeuVal: 7.346 ± 0.493
0.0LeuTrp: 0.0 ± 0.0
1.959LeuTyr: 1.959 ± 0.94
0.0LeuXaa: 0.0 ± 0.0
Met
1.469MetAla: 1.469 ± 0.705
0.0MetCys: 0.0 ± 0.0
2.938MetAsp: 2.938 ± 1.41
2.938MetGlu: 2.938 ± 1.41
0.49MetPhe: 0.49 ± 0.235
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.469MetIle: 1.469 ± 0.705
1.469MetLys: 1.469 ± 0.705
2.449MetLeu: 2.449 ± 1.175
0.49MetMet: 0.49 ± 0.235
0.979MetAsn: 0.979 ± 0.47
1.469MetPro: 1.469 ± 0.705
1.469MetGln: 1.469 ± 0.705
0.0MetArg: 0.0 ± 0.0
2.449MetSer: 2.449 ± 1.966
1.469MetThr: 1.469 ± 0.705
0.0MetVal: 0.0 ± 0.0
0.49MetTrp: 0.49 ± 0.235
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.449AsnAla: 2.449 ± 1.087
0.49AsnCys: 0.49 ± 0.235
2.449AsnAsp: 2.449 ± 1.087
1.959AsnGlu: 1.959 ± 0.94
2.938AsnPhe: 2.938 ± 1.41
2.449AsnGly: 2.449 ± 1.175
0.0AsnHis: 0.0 ± 0.0
3.428AsnIle: 3.428 ± 4.559
3.428AsnLys: 3.428 ± 6.394
4.897AsnLeu: 4.897 ± 4.463
0.979AsnMet: 0.979 ± 0.47
1.469AsnAsn: 1.469 ± 1.374
1.959AsnPro: 1.959 ± 1.331
1.959AsnGln: 1.959 ± 0.94
1.469AsnArg: 1.469 ± 0.705
2.938AsnSer: 2.938 ± 3.488
2.938AsnThr: 2.938 ± 1.41
1.959AsnVal: 1.959 ± 1.217
0.979AsnTrp: 0.979 ± 1.566
2.449AsnTyr: 2.449 ± 1.175
0.0AsnXaa: 0.0 ± 0.0
Pro
3.918ProAla: 3.918 ± 1.318
0.49ProCys: 0.49 ± 0.235
2.449ProAsp: 2.449 ± 1.175
1.469ProGlu: 1.469 ± 0.705
0.49ProPhe: 0.49 ± 0.235
2.449ProGly: 2.449 ± 1.175
0.979ProHis: 0.979 ± 0.47
0.49ProIle: 0.49 ± 0.235
3.918ProLys: 3.918 ± 2.433
2.449ProLeu: 2.449 ± 1.087
0.49ProMet: 0.49 ± 0.235
3.918ProAsn: 3.918 ± 2.663
1.959ProPro: 1.959 ± 0.94
0.49ProGln: 0.49 ± 0.235
3.918ProArg: 3.918 ± 2.663
4.407ProSer: 4.407 ± 2.116
1.469ProThr: 1.469 ± 0.705
0.49ProVal: 0.49 ± 0.235
0.979ProTrp: 0.979 ± 0.47
0.49ProTyr: 0.49 ± 1.72
0.0ProXaa: 0.0 ± 0.0
Gln
3.428GlnAla: 3.428 ± 0.958
0.0GlnCys: 0.0 ± 0.0
2.938GlnAsp: 2.938 ± 1.239
3.428GlnGlu: 3.428 ± 3.238
0.979GlnPhe: 0.979 ± 0.47
0.979GlnGly: 0.979 ± 0.47
0.979GlnHis: 0.979 ± 0.47
3.918GlnIle: 3.918 ± 1.881
2.449GlnLys: 2.449 ± 4.842
3.428GlnLeu: 3.428 ± 1.502
0.0GlnMet: 0.0 ± 1.333
2.449GlnAsn: 2.449 ± 1.175
2.449GlnPro: 2.449 ± 1.087
4.407GlnGln: 4.407 ± 2.296
3.428GlnArg: 3.428 ± 1.645
0.49GlnSer: 0.49 ± 0.235
2.449GlnThr: 2.449 ± 1.087
3.918GlnVal: 3.918 ± 1.881
0.0GlnTrp: 0.0 ± 0.0
1.959GlnTyr: 1.959 ± 0.94
0.0GlnXaa: 0.0 ± 0.0
Arg
4.897ArgAla: 4.897 ± 0.82
0.49ArgCys: 0.49 ± 1.743
3.918ArgAsp: 3.918 ± 1.881
3.918ArgGlu: 3.918 ± 1.318
1.959ArgPhe: 1.959 ± 0.94
1.469ArgGly: 1.469 ± 0.705
0.49ArgHis: 0.49 ± 0.235
4.407ArgIle: 4.407 ± 2.116
2.938ArgLys: 2.938 ± 1.41
5.877ArgLeu: 5.877 ± 3.467
2.449ArgMet: 2.449 ± 1.175
2.449ArgAsn: 2.449 ± 1.966
2.938ArgPro: 2.938 ± 1.239
2.449ArgGln: 2.449 ± 1.264
1.959ArgArg: 1.959 ± 0.94
6.856ArgSer: 6.856 ± 3.291
3.918ArgThr: 3.918 ± 1.881
3.918ArgVal: 3.918 ± 1.272
1.959ArgTrp: 1.959 ± 0.94
1.959ArgTyr: 1.959 ± 0.94
0.0ArgXaa: 0.0 ± 0.0
Ser
2.449SerAla: 2.449 ± 1.264
0.0SerCys: 0.0 ± 0.0
2.938SerAsp: 2.938 ± 2.869
5.877SerGlu: 5.877 ± 1.995
1.469SerPhe: 1.469 ± 1.374
4.407SerGly: 4.407 ± 2.116
0.49SerHis: 0.49 ± 1.743
4.407SerIle: 4.407 ± 1.416
6.366SerLys: 6.366 ± 3.815
5.877SerLeu: 5.877 ± 2.477
0.979SerMet: 0.979 ± 0.47
0.979SerAsn: 0.979 ± 0.47
1.959SerPro: 1.959 ± 0.94
4.897SerGln: 4.897 ± 1.162
3.918SerArg: 3.918 ± 2.663
3.918SerSer: 3.918 ± 1.272
1.959SerThr: 1.959 ± 0.94
2.449SerVal: 2.449 ± 1.264
0.49SerTrp: 0.49 ± 0.235
1.469SerTyr: 1.469 ± 0.705
0.0SerXaa: 0.0 ± 0.0
Thr
3.428ThrAla: 3.428 ± 1.257
0.0ThrCys: 0.0 ± 0.0
0.979ThrAsp: 0.979 ± 0.47
5.387ThrGlu: 5.387 ± 0.605
3.428ThrPhe: 3.428 ± 1.645
3.918ThrGly: 3.918 ± 1.318
0.979ThrHis: 0.979 ± 0.47
4.897ThrIle: 4.897 ± 2.351
4.897ThrLys: 4.897 ± 1.544
3.918ThrLeu: 3.918 ± 2.433
0.49ThrMet: 0.49 ± 0.235
0.49ThrAsn: 0.49 ± 0.235
2.449ThrPro: 2.449 ± 1.264
1.959ThrGln: 1.959 ± 1.331
2.449ThrArg: 2.449 ± 1.175
4.407ThrSer: 4.407 ± 1.416
5.877ThrThr: 5.877 ± 1.863
0.979ThrVal: 0.979 ± 0.47
0.979ThrTrp: 0.979 ± 0.47
0.49ThrTyr: 0.49 ± 0.235
0.0ThrXaa: 0.0 ± 0.0
Val
4.897ValAla: 4.897 ± 1.162
0.979ValCys: 0.979 ± 0.47
1.959ValAsp: 1.959 ± 0.94
3.428ValGlu: 3.428 ± 2.585
2.938ValPhe: 2.938 ± 1.41
2.449ValGly: 2.449 ± 1.264
0.979ValHis: 0.979 ± 0.47
4.407ValIle: 4.407 ± 2.78
3.428ValLys: 3.428 ± 3.278
4.897ValLeu: 4.897 ± 2.553
1.959ValMet: 1.959 ± 0.94
1.959ValAsn: 1.959 ± 1.217
1.959ValPro: 1.959 ± 1.331
1.959ValGln: 1.959 ± 1.217
3.918ValArg: 3.918 ± 1.318
1.959ValSer: 1.959 ± 0.94
3.428ValThr: 3.428 ± 0.958
3.918ValVal: 3.918 ± 1.881
0.0ValTrp: 0.0 ± 0.0
2.938ValTyr: 2.938 ± 1.239
0.0ValXaa: 0.0 ± 0.0
Trp
0.979TrpAla: 0.979 ± 0.47
0.0TrpCys: 0.0 ± 0.0
0.49TrpAsp: 0.49 ± 0.235
1.469TrpGlu: 1.469 ± 2.432
0.0TrpPhe: 0.0 ± 0.0
0.49TrpGly: 0.49 ± 0.235
0.49TrpHis: 0.49 ± 0.235
0.49TrpIle: 0.49 ± 0.235
1.469TrpLys: 1.469 ± 1.435
1.959TrpLeu: 1.959 ± 0.94
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.49TrpPro: 0.49 ± 0.235
0.49TrpGln: 0.49 ± 0.235
1.469TrpArg: 1.469 ± 0.705
0.49TrpSer: 0.49 ± 0.235
0.979TrpThr: 0.979 ± 0.47
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.428TyrAla: 3.428 ± 1.645
0.49TyrCys: 0.49 ± 0.235
2.938TyrAsp: 2.938 ± 1.41
3.428TyrGlu: 3.428 ± 1.645
0.49TyrPhe: 0.49 ± 0.235
0.49TyrGly: 0.49 ± 0.235
0.979TyrHis: 0.979 ± 0.47
2.449TyrIle: 2.449 ± 1.175
2.938TyrLys: 2.938 ± 0.998
2.449TyrLeu: 2.449 ± 1.087
1.469TyrMet: 1.469 ± 0.705
2.449TyrAsn: 2.449 ± 1.966
0.49TyrPro: 0.49 ± 0.235
0.979TyrGln: 0.979 ± 1.566
3.918TyrArg: 3.918 ± 0.976
1.959TyrSer: 1.959 ± 0.94
0.979TyrThr: 0.979 ± 0.47
0.979TyrVal: 0.979 ± 0.47
0.0TyrTrp: 0.0 ± 0.0
1.959TyrTyr: 1.959 ± 0.94
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2043 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski