Amino acid dipepetide frequency for Sporomusa malonica

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.599AlaAla: 10.599 ± 0.135	1.149AlaCys: 1.149 ± 0.031	4.652AlaAsp: 4.652 ± 0.056	5.812AlaGlu: 5.812 ± 0.078	3.158AlaPhe: 3.158 ± 0.051	8.029AlaGly: 8.029 ± 0.104	1.462AlaHis: 1.462 ± 0.032	6.727AlaIle: 6.727 ± 0.073	5.542AlaLys: 5.542 ± 0.07	8.605AlaLeu: 8.605 ± 0.081	2.656AlaMet: 2.656 ± 0.045	3.367AlaAsn: 3.367 ± 0.054	2.621AlaPro: 2.621 ± 0.046	3.287AlaGln: 3.287 ± 0.052	3.955AlaArg: 3.955 ± 0.06	4.678AlaSer: 4.678 ± 0.069	4.472AlaThr: 4.472 ± 0.074	7.763AlaVal: 7.763 ± 0.072	0.749AlaTrp: 0.749 ± 0.024	2.614AlaTyr: 2.614 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.928CysAla: 0.928 ± 0.028	0.242CysCys: 0.242 ± 0.014	0.563CysAsp: 0.563 ± 0.018	0.624CysGlu: 0.624 ± 0.02	0.46CysPhe: 0.46 ± 0.017	1.289CysGly: 1.289 ± 0.034	0.305CysHis: 0.305 ± 0.014	0.849CysIle: 0.849 ± 0.023	0.574CysLys: 0.574 ± 0.02	1.1CysLeu: 1.1 ± 0.028	0.33CysMet: 0.33 ± 0.014	0.477CysAsn: 0.477 ± 0.018	0.725CysPro: 0.725 ± 0.029	0.525CysGln: 0.525 ± 0.018	0.653CysArg: 0.653 ± 0.021	0.797CysSer: 0.797 ± 0.024	0.654CysThr: 0.654 ± 0.022	0.766CysVal: 0.766 ± 0.027	0.12CysTrp: 0.12 ± 0.009	0.392CysTyr: 0.392 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.867AspAla: 3.867 ± 0.056	0.681AspCys: 0.681 ± 0.024	2.236AspAsp: 2.236 ± 0.04	3.222AspGlu: 3.222 ± 0.051	2.065AspPhe: 2.065 ± 0.044	3.49AspGly: 3.49 ± 0.061	0.853AspHis: 0.853 ± 0.024	4.53AspIle: 4.53 ± 0.066	3.343AspLys: 3.343 ± 0.052	4.51AspLeu: 4.51 ± 0.051	1.449AspMet: 1.449 ± 0.032	2.146AspAsn: 2.146 ± 0.045	1.812AspPro: 1.812 ± 0.035	1.541AspGln: 1.541 ± 0.031	2.284AspArg: 2.284 ± 0.033	2.691AspSer: 2.691 ± 0.047	2.67AspThr: 2.67 ± 0.053	3.605AspVal: 3.605 ± 0.06	0.57AspTrp: 0.57 ± 0.02	1.998AspTyr: 1.998 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	5.431GluAla: 5.431 ± 0.07	0.64GluCys: 0.64 ± 0.021	2.601GluAsp: 2.601 ± 0.043	4.105GluGlu: 4.105 ± 0.056	2.345GluPhe: 2.345 ± 0.045	3.448GluGly: 3.448 ± 0.054	1.264GluHis: 1.264 ± 0.031	4.882GluIle: 4.882 ± 0.076	4.334GluLys: 4.334 ± 0.061	6.773GluLeu: 6.773 ± 0.084	1.873GluMet: 1.873 ± 0.035	2.547GluAsn: 2.547 ± 0.041	1.828GluPro: 1.828 ± 0.036	3.013GluGln: 3.013 ± 0.06	3.225GluArg: 3.225 ± 0.052	2.783GluSer: 2.783 ± 0.045	3.277GluThr: 3.277 ± 0.048	4.498GluVal: 4.498 ± 0.057	0.584GluTrp: 0.584 ± 0.02	2.133GluTyr: 2.133 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.444PheAla: 3.444 ± 0.05	0.562PheCys: 0.562 ± 0.021	2.067PheAsp: 2.067 ± 0.041	1.983PheGlu: 1.983 ± 0.039	1.644PhePhe: 1.644 ± 0.038	3.182PheGly: 3.182 ± 0.051	0.679PheHis: 0.679 ± 0.024	2.905PheIle: 2.905 ± 0.052	1.843PheLys: 1.843 ± 0.036	3.518PheLeu: 3.518 ± 0.059	1.015PheMet: 1.015 ± 0.028	1.624PheAsn: 1.624 ± 0.037	1.411PhePro: 1.411 ± 0.029	1.072PheGln: 1.072 ± 0.029	1.6PheArg: 1.6 ± 0.034	2.689PheSer: 2.689 ± 0.045	2.312PheThr: 2.312 ± 0.037	2.755PheVal: 2.755 ± 0.043	0.439PheTrp: 0.439 ± 0.019	1.261PheTyr: 1.261 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	6.311GlyAla: 6.311 ± 0.099	1.163GlyCys: 1.163 ± 0.031	3.425GlyAsp: 3.425 ± 0.058	4.162GlyGlu: 4.162 ± 0.063	3.165GlyPhe: 3.165 ± 0.041	5.774GlyGly: 5.774 ± 0.089	1.452GlyHis: 1.452 ± 0.033	6.312GlyIle: 6.312 ± 0.073	4.827GlyLys: 4.827 ± 0.056	7.596GlyLeu: 7.596 ± 0.081	2.444GlyMet: 2.444 ± 0.045	2.878GlyAsn: 2.878 ± 0.086	1.996GlyPro: 1.996 ± 0.039	3.109GlyGln: 3.109 ± 0.058	3.47GlyArg: 3.47 ± 0.054	4.317GlySer: 4.317 ± 0.077	4.354GlyThr: 4.354 ± 0.077	5.756GlyVal: 5.756 ± 0.062	0.822GlyTrp: 0.822 ± 0.028	2.84GlyTyr: 2.84 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.366HisAla: 1.366 ± 0.028	0.291HisCys: 0.291 ± 0.01	0.955HisAsp: 0.955 ± 0.026	1.079HisGlu: 1.079 ± 0.028	0.721HisPhe: 0.721 ± 0.022	1.424HisGly: 1.424 ± 0.03	0.497HisHis: 0.497 ± 0.019	1.399HisIle: 1.399 ± 0.031	0.958HisLys: 0.958 ± 0.025	1.709HisLeu: 1.709 ± 0.038	0.497HisMet: 0.497 ± 0.02	0.784HisAsn: 0.784 ± 0.023	0.957HisPro: 0.957 ± 0.029	0.696HisGln: 0.696 ± 0.019	0.882HisArg: 0.882 ± 0.023	1.122HisSer: 1.122 ± 0.027	1.005HisThr: 1.005 ± 0.03	1.199HisVal: 1.199 ± 0.03	0.23HisTrp: 0.23 ± 0.011	0.671HisTyr: 0.671 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.143IleAla: 7.143 ± 0.072	0.863IleCys: 0.863 ± 0.024	4.128IleAsp: 4.128 ± 0.054	4.663IleGlu: 4.663 ± 0.056	2.571IlePhe: 2.571 ± 0.043	5.772IleGly: 5.772 ± 0.069	1.277IleHis: 1.277 ± 0.034	5.77IleIle: 5.77 ± 0.073	4.382IleLys: 4.382 ± 0.06	6.504IleLeu: 6.504 ± 0.085	1.915IleMet: 1.915 ± 0.034	3.376IleAsn: 3.376 ± 0.052	3.305IlePro: 3.305 ± 0.056	2.215IleGln: 2.215 ± 0.038	3.255IleArg: 3.255 ± 0.053	4.617IleSer: 4.617 ± 0.058	4.625IleThr: 4.625 ± 0.065	5.631IleVal: 5.631 ± 0.07	0.577IleTrp: 0.577 ± 0.019	2.144IleTyr: 2.144 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	5.163LysAla: 5.163 ± 0.065	0.585LysCys: 0.585 ± 0.021	2.931LysAsp: 2.931 ± 0.046	4.105LysGlu: 4.105 ± 0.067	1.805LysPhe: 1.805 ± 0.039	3.567LysGly: 3.567 ± 0.047	1.041LysHis: 1.041 ± 0.025	4.272LysIle: 4.272 ± 0.064	3.619LysLys: 3.619 ± 0.052	5.789LysLeu: 5.789 ± 0.066	1.836LysMet: 1.836 ± 0.041	2.644LysAsn: 2.644 ± 0.047	2.406LysPro: 2.406 ± 0.039	2.577LysGln: 2.577 ± 0.039	2.528LysArg: 2.528 ± 0.044	2.882LysSer: 2.882 ± 0.051	3.258LysThr: 3.258 ± 0.041	4.492LysVal: 4.492 ± 0.061	0.556LysTrp: 0.556 ± 0.019	1.921LysTyr: 1.921 ± 0.041	0.0LysXaa: 0.0 ± 0.0
Leu	10.287LeuAla: 10.287 ± 0.102	1.142LeuCys: 1.142 ± 0.029	4.864LeuAsp: 4.864 ± 0.055	5.706LeuGlu: 5.706 ± 0.067	3.697LeuPhe: 3.697 ± 0.058	7.353LeuGly: 7.353 ± 0.092	1.628LeuHis: 1.628 ± 0.034	6.465LeuIle: 6.465 ± 0.075	5.654LeuLys: 5.654 ± 0.061	9.391LeuLeu: 9.391 ± 0.105	2.462LeuMet: 2.462 ± 0.04	3.925LeuAsn: 3.925 ± 0.055	4.38LeuPro: 4.38 ± 0.051	3.111LeuGln: 3.111 ± 0.045	4.175LeuArg: 4.175 ± 0.063	6.245LeuSer: 6.245 ± 0.071	6.254LeuThr: 6.254 ± 0.071	7.024LeuVal: 7.024 ± 0.071	0.857LeuTrp: 0.857 ± 0.024	2.675LeuTyr: 2.675 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.91MetAla: 2.91 ± 0.048	0.265MetCys: 0.265 ± 0.014	1.327MetAsp: 1.327 ± 0.028	1.611MetGlu: 1.611 ± 0.042	0.908MetPhe: 0.908 ± 0.024	2.081MetGly: 2.081 ± 0.045	0.452MetHis: 0.452 ± 0.016	1.833MetIle: 1.833 ± 0.038	1.64MetLys: 1.64 ± 0.035	2.808MetLeu: 2.808 ± 0.046	0.795MetMet: 0.795 ± 0.024	1.215MetAsn: 1.215 ± 0.033	1.255MetPro: 1.255 ± 0.029	1.016MetGln: 1.016 ± 0.029	1.256MetArg: 1.256 ± 0.028	1.82MetSer: 1.82 ± 0.032	1.646MetThr: 1.646 ± 0.032	2.023MetVal: 2.023 ± 0.033	0.201MetTrp: 0.201 ± 0.011	0.701MetTyr: 0.701 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.141AsnAla: 3.141 ± 0.05	0.564AsnCys: 0.564 ± 0.021	1.857AsnAsp: 1.857 ± 0.042	2.205AsnGlu: 2.205 ± 0.045	1.517AsnPhe: 1.517 ± 0.033	2.86AsnGly: 2.86 ± 0.061	0.808AsnHis: 0.808 ± 0.023	3.498AsnIle: 3.498 ± 0.059	2.433AsnLys: 2.433 ± 0.046	4.006AsnLeu: 4.006 ± 0.059	1.161AsnMet: 1.161 ± 0.029	1.992AsnAsn: 1.992 ± 0.053	2.114AsnPro: 2.114 ± 0.035	1.657AsnGln: 1.657 ± 0.038	1.903AsnArg: 1.903 ± 0.035	2.452AsnSer: 2.452 ± 0.054	2.338AsnThr: 2.338 ± 0.051	2.816AsnVal: 2.816 ± 0.045	0.453AsnTrp: 0.453 ± 0.02	1.444AsnTyr: 1.444 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	3.564ProAla: 3.564 ± 0.06	0.443ProCys: 0.443 ± 0.018	2.403ProAsp: 2.403 ± 0.042	3.171ProGlu: 3.171 ± 0.054	1.636ProPhe: 1.636 ± 0.03	3.265ProGly: 3.265 ± 0.058	0.786ProHis: 0.786 ± 0.023	2.524ProIle: 2.524 ± 0.045	1.844ProLys: 1.844 ± 0.035	3.722ProLeu: 3.722 ± 0.055	0.87ProMet: 0.87 ± 0.025	1.416ProAsn: 1.416 ± 0.031	1.413ProPro: 1.413 ± 0.035	1.402ProGln: 1.402 ± 0.029	1.395ProArg: 1.395 ± 0.028	1.928ProSer: 1.928 ± 0.036	1.94ProThr: 1.94 ± 0.043	3.593ProVal: 3.593 ± 0.054	0.408ProTrp: 0.408 ± 0.018	1.297ProTyr: 1.297 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.921GlnAla: 3.921 ± 0.056	0.37GlnCys: 0.37 ± 0.015	1.808GlnAsp: 1.808 ± 0.038	2.634GlnGlu: 2.634 ± 0.042	1.266GlnPhe: 1.266 ± 0.029	2.729GlnGly: 2.729 ± 0.054	0.701GlnHis: 0.701 ± 0.021	2.584GlnIle: 2.584 ± 0.042	2.021GlnLys: 2.021 ± 0.041	3.642GlnLeu: 3.642 ± 0.051	1.077GlnMet: 1.077 ± 0.031	1.537GlnAsn: 1.537 ± 0.034	1.555GlnPro: 1.555 ± 0.034	1.91GlnGln: 1.91 ± 0.051	1.624GlnArg: 1.624 ± 0.034	2.119GlnSer: 2.119 ± 0.043	2.017GlnThr: 2.017 ± 0.037	2.909GlnVal: 2.909 ± 0.048	0.304GlnTrp: 0.304 ± 0.014	1.21GlnTyr: 1.21 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	3.163ArgAla: 3.163 ± 0.049	0.564ArgCys: 0.564 ± 0.022	2.247ArgAsp: 2.247 ± 0.039	3.3ArgGlu: 3.3 ± 0.053	1.768ArgPhe: 1.768 ± 0.036	2.779ArgGly: 2.779 ± 0.049	0.952ArgHis: 0.952 ± 0.028	3.302ArgIle: 3.302 ± 0.05	2.695ArgLys: 2.695 ± 0.047	4.742ArgLeu: 4.742 ± 0.065	1.367ArgMet: 1.367 ± 0.029	1.782ArgAsn: 1.782 ± 0.035	1.719ArgPro: 1.719 ± 0.038	2.398ArgGln: 2.398 ± 0.047	2.341ArgArg: 2.341 ± 0.044	2.249ArgSer: 2.249 ± 0.046	2.3ArgThr: 2.3 ± 0.042	3.144ArgVal: 3.144 ± 0.055	0.463ArgTrp: 0.463 ± 0.017	1.596ArgTyr: 1.596 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	4.724SerAla: 4.724 ± 0.058	0.697SerCys: 0.697 ± 0.022	2.686SerAsp: 2.686 ± 0.05	3.25SerGlu: 3.25 ± 0.05	2.34SerPhe: 2.34 ± 0.044	5.104SerGly: 5.104 ± 0.089	1.175SerHis: 1.175 ± 0.028	4.196SerIle: 4.196 ± 0.057	3.006SerLys: 3.006 ± 0.047	5.801SerLeu: 5.801 ± 0.062	1.571SerMet: 1.571 ± 0.029	2.139SerAsn: 2.139 ± 0.044	2.32SerPro: 2.32 ± 0.042	2.357SerGln: 2.357 ± 0.04	2.688SerArg: 2.688 ± 0.046	3.559SerSer: 3.559 ± 0.068	3.041SerThr: 3.041 ± 0.051	4.053SerVal: 4.053 ± 0.06	0.599SerTrp: 0.599 ± 0.021	1.919SerTyr: 1.919 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.655ThrAla: 5.655 ± 0.078	0.61ThrCys: 0.61 ± 0.02	2.765ThrAsp: 2.765 ± 0.05	3.018ThrGlu: 3.018 ± 0.046	2.051ThrPhe: 2.051 ± 0.041	5.383ThrGly: 5.383 ± 0.1	0.973ThrHis: 0.973 ± 0.023	4.287ThrIle: 4.287 ± 0.065	2.755ThrLys: 2.755 ± 0.046	5.291ThrLeu: 5.291 ± 0.062	1.473ThrMet: 1.473 ± 0.033	2.268ThrAsn: 2.268 ± 0.052	2.58ThrPro: 2.58 ± 0.045	1.759ThrGln: 1.759 ± 0.036	2.108ThrArg: 2.108 ± 0.037	3.038ThrSer: 3.038 ± 0.047	3.331ThrThr: 3.331 ± 0.059	4.859ThrVal: 4.859 ± 0.065	0.503ThrTrp: 0.503 ± 0.019	1.629ThrTyr: 1.629 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.116ValAla: 7.116 ± 0.082	0.943ValCys: 0.943 ± 0.025	3.919ValAsp: 3.919 ± 0.054	4.564ValGlu: 4.564 ± 0.062	3.029ValPhe: 3.029 ± 0.046	5.308ValGly: 5.308 ± 0.062	1.219ValHis: 1.219 ± 0.029	5.691ValIle: 5.691 ± 0.071	4.408ValLys: 4.408 ± 0.059	7.35ValLeu: 7.35 ± 0.073	2.041ValMet: 2.041 ± 0.037	3.274ValAsn: 3.274 ± 0.051	2.881ValPro: 2.881 ± 0.047	2.296ValGln: 2.296 ± 0.04	3.304ValArg: 3.304 ± 0.052	4.716ValSer: 4.716 ± 0.054	4.623ValThr: 4.623 ± 0.064	6.031ValVal: 6.031 ± 0.071	0.648ValTrp: 0.648 ± 0.022	2.294ValTyr: 2.294 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.711TrpAla: 0.711 ± 0.026	0.104TrpCys: 0.104 ± 0.009	0.449TrpAsp: 0.449 ± 0.019	0.578TrpGlu: 0.578 ± 0.02	0.424TrpPhe: 0.424 ± 0.018	0.786TrpGly: 0.786 ± 0.025	0.216TrpHis: 0.216 ± 0.012	0.525TrpIle: 0.525 ± 0.02	0.452TrpLys: 0.452 ± 0.019	1.196TrpLeu: 1.196 ± 0.029	0.245TrpMet: 0.245 ± 0.013	0.406TrpAsn: 0.406 ± 0.016	0.382TrpPro: 0.382 ± 0.017	0.568TrpGln: 0.568 ± 0.023	0.516TrpArg: 0.516 ± 0.019	0.526TrpSer: 0.526 ± 0.019	0.428TrpThr: 0.428 ± 0.018	0.655TrpVal: 0.655 ± 0.026	0.165TrpTrp: 0.165 ± 0.011	0.301TrpTyr: 0.301 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.454TyrAla: 2.454 ± 0.04	0.496TyrCys: 0.496 ± 0.017	1.68TyrAsp: 1.68 ± 0.037	1.791TyrGlu: 1.791 ± 0.037	1.436TyrPhe: 1.436 ± 0.037	2.549TyrGly: 2.549 ± 0.047	0.701TyrHis: 0.701 ± 0.021	2.181TyrIle: 2.181 ± 0.045	1.646TyrLys: 1.646 ± 0.035	3.241TyrLeu: 3.241 ± 0.059	0.687TyrMet: 0.687 ± 0.022	1.423TyrAsn: 1.423 ± 0.035	1.362TyrPro: 1.362 ± 0.034	1.431TyrGln: 1.431 ± 0.032	1.71TyrArg: 1.71 ± 0.036	2.0TyrSer: 2.0 ± 0.038	1.79TyrThr: 1.79 ± 0.042	2.08TyrVal: 2.08 ± 0.035	0.385TyrTrp: 0.385 ± 0.018	1.259TyrTyr: 1.259 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4926 proteins (1505841 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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