Amino acid dipepetide frequency for Alphamesonivirus 1 (isolate Aedes harrisoni/Cote d Ivoire/C79/2004)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.882AlaAla: 2.882 ± 0.933
1.219AlaCys: 1.219 ± 0.429
2.66AlaAsp: 2.66 ± 0.391
3.546AlaGlu: 3.546 ± 0.764
2.217AlaPhe: 2.217 ± 0.611
0.665AlaGly: 0.665 ± 0.137
1.884AlaHis: 1.884 ± 0.31
6.761AlaIle: 6.761 ± 0.53
4.322AlaLys: 4.322 ± 0.615
5.763AlaLeu: 5.763 ± 0.418
1.219AlaMet: 1.219 ± 1.567
3.657AlaAsn: 3.657 ± 0.458
1.441AlaPro: 1.441 ± 0.503
2.438AlaGln: 2.438 ± 0.879
2.66AlaArg: 2.66 ± 0.468
2.66AlaSer: 2.66 ± 0.738
3.436AlaThr: 3.436 ± 0.625
2.771AlaVal: 2.771 ± 0.273
0.443AlaTrp: 0.443 ± 0.169
4.433AlaTyr: 4.433 ± 0.908
0.0AlaXaa: 0.0 ± 0.0
Cys
0.887CysAla: 0.887 ± 0.288
0.111CysCys: 0.111 ± 0.064
0.887CysAsp: 0.887 ± 0.313
0.997CysGlu: 0.997 ± 0.345
0.997CysPhe: 0.997 ± 0.324
1.33CysGly: 1.33 ± 0.234
0.554CysHis: 0.554 ± 0.214
1.662CysIle: 1.662 ± 0.479
2.217CysLys: 2.217 ± 0.291
1.441CysLeu: 1.441 ± 0.208
0.554CysMet: 0.554 ± 0.183
1.33CysAsn: 1.33 ± 0.274
0.997CysPro: 0.997 ± 0.445
0.332CysGln: 0.332 ± 0.185
0.554CysArg: 0.554 ± 0.122
0.554CysSer: 0.554 ± 0.497
2.217CysThr: 2.217 ± 0.453
1.33CysVal: 1.33 ± 0.24
0.0CysTrp: 0.0 ± 0.0
1.108CysTyr: 1.108 ± 0.339
0.0CysXaa: 0.0 ± 0.0
Asp
2.549AspAla: 2.549 ± 1.05
1.108AspCys: 1.108 ± 0.428
3.436AspAsp: 3.436 ± 0.421
1.662AspGlu: 1.662 ± 0.292
3.657AspPhe: 3.657 ± 0.811
1.219AspGly: 1.219 ± 0.439
1.552AspHis: 1.552 ± 0.373
3.879AspIle: 3.879 ± 0.646
1.662AspLys: 1.662 ± 0.567
5.541AspLeu: 5.541 ± 0.436
0.332AspMet: 0.332 ± 0.185
3.879AspAsn: 3.879 ± 1.272
2.882AspPro: 2.882 ± 0.777
1.441AspGln: 1.441 ± 0.387
1.773AspArg: 1.773 ± 0.511
3.103AspSer: 3.103 ± 0.567
4.987AspThr: 4.987 ± 0.777
3.657AspVal: 3.657 ± 0.757
0.443AspTrp: 0.443 ± 0.157
3.657AspTyr: 3.657 ± 0.55
0.0AspXaa: 0.0 ± 0.0
Glu
1.995GluAla: 1.995 ± 0.225
1.108GluCys: 1.108 ± 0.213
1.884GluAsp: 1.884 ± 0.357
1.662GluGlu: 1.662 ± 0.204
3.879GluPhe: 3.879 ± 0.35
0.776GluGly: 0.776 ± 0.185
2.882GluHis: 2.882 ± 0.364
3.99GluIle: 3.99 ± 1.055
2.992GluLys: 2.992 ± 0.595
5.652GluLeu: 5.652 ± 0.996
1.219GluMet: 1.219 ± 0.191
2.549GluAsn: 2.549 ± 0.285
2.217GluPro: 2.217 ± 0.345
0.997GluGln: 0.997 ± 0.249
1.441GluArg: 1.441 ± 0.188
2.327GluSer: 2.327 ± 0.447
3.325GluThr: 3.325 ± 0.24
1.773GluVal: 1.773 ± 0.5
0.111GluTrp: 0.111 ± 0.064
1.662GluTyr: 1.662 ± 0.49
0.0GluXaa: 0.0 ± 0.0
Phe
2.327PheAla: 2.327 ± 0.413
0.776PheCys: 0.776 ± 0.367
3.103PheAsp: 3.103 ± 0.524
2.217PheGlu: 2.217 ± 0.248
0.443PhePhe: 0.443 ± 0.169
2.549PheGly: 2.549 ± 0.391
0.222PheHis: 0.222 ± 0.197
2.992PheIle: 2.992 ± 0.583
1.995PheLys: 1.995 ± 0.68
3.546PheLeu: 3.546 ± 0.272
1.219PheMet: 1.219 ± 0.395
3.325PheAsn: 3.325 ± 0.483
0.332PhePro: 0.332 ± 0.185
0.887PheGln: 0.887 ± 0.277
0.997PheArg: 0.997 ± 0.543
1.884PheSer: 1.884 ± 0.635
3.768PheThr: 3.768 ± 0.656
3.325PheVal: 3.325 ± 0.403
0.222PheTrp: 0.222 ± 0.084
1.773PheTyr: 1.773 ± 0.354
0.0PheXaa: 0.0 ± 0.0
Gly
1.33GlyAla: 1.33 ± 0.314
0.554GlyCys: 0.554 ± 0.183
1.108GlyAsp: 1.108 ± 0.428
1.441GlyGlu: 1.441 ± 0.636
1.773GlyPhe: 1.773 ± 0.224
1.33GlyGly: 1.33 ± 0.274
0.776GlyHis: 0.776 ± 0.263
1.441GlyIle: 1.441 ± 0.54
2.438GlyLys: 2.438 ± 0.439
3.546GlyLeu: 3.546 ± 0.891
0.665GlyMet: 0.665 ± 0.216
1.441GlyAsn: 1.441 ± 0.217
1.441GlyPro: 1.441 ± 0.324
0.776GlyGln: 0.776 ± 0.185
1.552GlyArg: 1.552 ± 0.37
2.106GlySer: 2.106 ± 0.865
2.882GlyThr: 2.882 ± 0.477
1.773GlyVal: 1.773 ± 0.457
0.443GlyTrp: 0.443 ± 0.395
1.884GlyTyr: 1.884 ± 0.32
0.0GlyXaa: 0.0 ± 0.0
His
1.995HisAla: 1.995 ± 0.26
0.997HisCys: 0.997 ± 0.292
1.219HisAsp: 1.219 ± 0.191
1.33HisGlu: 1.33 ± 0.274
1.552HisPhe: 1.552 ± 0.377
0.997HisGly: 0.997 ± 0.312
1.441HisHis: 1.441 ± 0.389
2.882HisIle: 2.882 ± 0.364
3.103HisLys: 3.103 ± 0.573
3.768HisLeu: 3.768 ± 0.806
1.108HisMet: 1.108 ± 0.279
2.66HisAsn: 2.66 ± 0.55
2.438HisPro: 2.438 ± 0.381
1.884HisGln: 1.884 ± 0.594
0.887HisArg: 0.887 ± 0.313
1.773HisSer: 1.773 ± 0.499
3.879HisThr: 3.879 ± 0.464
1.552HisVal: 1.552 ± 0.247
0.222HisTrp: 0.222 ± 0.129
1.995HisTyr: 1.995 ± 0.913
0.0HisXaa: 0.0 ± 0.0
Ile
5.209IleAla: 5.209 ± 0.836
1.441IleCys: 1.441 ± 0.636
4.433IleAsp: 4.433 ± 0.598
3.768IleGlu: 3.768 ± 0.492
2.327IlePhe: 2.327 ± 0.487
1.773IleGly: 1.773 ± 0.431
2.217IleHis: 2.217 ± 0.808
4.544IleIle: 4.544 ± 0.645
5.32IleLys: 5.32 ± 1.141
7.204IleLeu: 7.204 ± 1.087
2.438IleMet: 2.438 ± 0.318
5.874IleAsn: 5.874 ± 1.319
4.322IlePro: 4.322 ± 0.726
3.103IleGln: 3.103 ± 0.326
3.657IleArg: 3.657 ± 0.683
3.103IleSer: 3.103 ± 0.74
5.32IleThr: 5.32 ± 0.459
3.657IleVal: 3.657 ± 0.268
0.776IleTrp: 0.776 ± 0.098
4.655IleTyr: 4.655 ± 0.501
0.0IleXaa: 0.0 ± 0.0
Lys
2.992LysAla: 2.992 ± 0.525
0.665LysCys: 0.665 ± 0.317
3.879LysAsp: 3.879 ± 0.574
1.995LysGlu: 1.995 ± 0.336
1.441LysPhe: 1.441 ± 0.309
1.219LysGly: 1.219 ± 0.395
3.436LysHis: 3.436 ± 0.907
4.655LysIle: 4.655 ± 0.393
2.327LysLys: 2.327 ± 0.211
7.093LysLeu: 7.093 ± 0.971
1.219LysMet: 1.219 ± 0.376
3.657LysAsn: 3.657 ± 0.578
4.655LysPro: 4.655 ± 0.449
3.657LysGln: 3.657 ± 1.115
2.549LysArg: 2.549 ± 0.641
4.101LysSer: 4.101 ± 0.32
4.322LysThr: 4.322 ± 0.64
2.771LysVal: 2.771 ± 0.633
0.443LysTrp: 0.443 ± 0.139
3.99LysTyr: 3.99 ± 0.341
0.0LysXaa: 0.0 ± 0.0
Leu
6.206LeuAla: 6.206 ± 0.867
1.773LeuCys: 1.773 ± 0.529
6.206LeuAsp: 6.206 ± 1.439
4.987LeuGlu: 4.987 ± 0.767
3.546LeuPhe: 3.546 ± 0.294
2.992LeuGly: 2.992 ± 0.458
3.436LeuHis: 3.436 ± 0.356
7.425LeuIle: 7.425 ± 0.825
7.758LeuLys: 7.758 ± 1.126
9.088LeuLeu: 9.088 ± 0.962
2.992LeuMet: 2.992 ± 0.502
6.65LeuAsn: 6.65 ± 1.094
3.436LeuPro: 3.436 ± 0.951
5.763LeuGln: 5.763 ± 0.447
5.209LeuArg: 5.209 ± 0.454
6.761LeuSer: 6.761 ± 0.674
7.425LeuThr: 7.425 ± 0.47
5.098LeuVal: 5.098 ± 0.604
0.776LeuTrp: 0.776 ± 0.175
5.763LeuTyr: 5.763 ± 0.807
0.0LeuXaa: 0.0 ± 0.0
Met
1.441MetAla: 1.441 ± 0.503
0.332MetCys: 0.332 ± 0.108
1.108MetAsp: 1.108 ± 0.339
1.33MetGlu: 1.33 ± 0.47
1.33MetPhe: 1.33 ± 0.287
0.776MetGly: 0.776 ± 0.507
0.222MetHis: 0.222 ± 0.197
0.997MetIle: 0.997 ± 0.313
0.997MetLys: 0.997 ± 0.163
3.879MetLeu: 3.879 ± 0.68
0.443MetMet: 0.443 ± 0.169
1.773MetAsn: 1.773 ± 0.37
0.997MetPro: 0.997 ± 0.264
1.773MetGln: 1.773 ± 0.354
0.887MetArg: 0.887 ± 0.288
1.219MetSer: 1.219 ± 0.392
0.887MetThr: 0.887 ± 0.313
0.776MetVal: 0.776 ± 0.098
0.0MetTrp: 0.0 ± 0.0
0.887MetTyr: 0.887 ± 0.31
0.0MetXaa: 0.0 ± 0.0
Asn
4.876AsnAla: 4.876 ± 2.704
1.219AsnCys: 1.219 ± 0.402
3.546AsnAsp: 3.546 ± 0.505
2.771AsnGlu: 2.771 ± 0.705
3.657AsnPhe: 3.657 ± 0.907
2.882AsnGly: 2.882 ± 0.631
2.771AsnHis: 2.771 ± 0.451
4.322AsnIle: 4.322 ± 0.955
4.433AsnLys: 4.433 ± 0.543
7.425AsnLeu: 7.425 ± 1.026
1.441AsnMet: 1.441 ± 0.525
6.539AsnAsn: 6.539 ± 0.661
3.879AsnPro: 3.879 ± 0.934
3.325AsnGln: 3.325 ± 0.429
2.438AsnArg: 2.438 ± 0.339
3.546AsnSer: 3.546 ± 2.078
6.206AsnThr: 6.206 ± 0.533
4.322AsnVal: 4.322 ± 0.526
0.554AsnTrp: 0.554 ± 0.183
4.544AsnTyr: 4.544 ± 0.575
0.0AsnXaa: 0.0 ± 0.0
Pro
3.546ProAla: 3.546 ± 0.87
0.332ProCys: 0.332 ± 0.179
1.995ProAsp: 1.995 ± 0.5
2.66ProGlu: 2.66 ± 0.251
0.443ProPhe: 0.443 ± 0.139
1.552ProGly: 1.552 ± 0.744
1.773ProHis: 1.773 ± 0.572
2.771ProIle: 2.771 ± 0.48
2.327ProLys: 2.327 ± 1.575
6.982ProLeu: 6.982 ± 0.63
0.443ProMet: 0.443 ± 0.395
2.327ProAsn: 2.327 ± 0.761
2.217ProPro: 2.217 ± 0.586
1.441ProGln: 1.441 ± 0.581
1.552ProArg: 1.552 ± 0.474
3.103ProSer: 3.103 ± 0.39
3.879ProThr: 3.879 ± 0.693
2.327ProVal: 2.327 ± 0.34
0.332ProTrp: 0.332 ± 0.108
2.327ProTyr: 2.327 ± 0.301
0.0ProXaa: 0.0 ± 0.0
Gln
2.66GlnAla: 2.66 ± 0.866
0.887GlnCys: 0.887 ± 0.288
1.662GlnAsp: 1.662 ± 0.543
1.441GlnGlu: 1.441 ± 0.282
0.997GlnPhe: 0.997 ± 0.743
1.108GlnGly: 1.108 ± 0.331
2.882GlnHis: 2.882 ± 0.455
1.995GlnIle: 1.995 ± 0.36
1.662GlnLys: 1.662 ± 0.209
5.431GlnLeu: 5.431 ± 0.639
0.111GlnMet: 0.111 ± 0.064
3.436GlnAsn: 3.436 ± 0.724
2.106GlnPro: 2.106 ± 1.641
1.995GlnGln: 1.995 ± 1.687
1.441GlnArg: 1.441 ± 0.611
2.771GlnSer: 2.771 ± 0.818
2.106GlnThr: 2.106 ± 0.467
1.441GlnVal: 1.441 ± 0.188
0.332GlnTrp: 0.332 ± 0.179
2.66GlnTyr: 2.66 ± 0.627
0.0GlnXaa: 0.0 ± 0.0
Arg
2.327ArgAla: 2.327 ± 0.756
0.443ArgCys: 0.443 ± 0.157
2.327ArgAsp: 2.327 ± 0.386
1.884ArgGlu: 1.884 ± 0.389
1.108ArgPhe: 1.108 ± 0.315
0.554ArgGly: 0.554 ± 0.183
1.219ArgHis: 1.219 ± 0.191
3.546ArgIle: 3.546 ± 0.398
3.546ArgLys: 3.546 ± 0.694
2.327ArgLeu: 2.327 ± 0.34
0.776ArgMet: 0.776 ± 0.312
3.546ArgAsn: 3.546 ± 0.985
0.997ArgPro: 0.997 ± 0.316
2.217ArgGln: 2.217 ± 0.714
2.217ArgArg: 2.217 ± 0.415
1.552ArgSer: 1.552 ± 0.777
3.546ArgThr: 3.546 ± 0.304
2.217ArgVal: 2.217 ± 0.461
0.332ArgTrp: 0.332 ± 0.266
4.544ArgTyr: 4.544 ± 1.27
0.0ArgXaa: 0.0 ± 0.0
Ser
3.657SerAla: 3.657 ± 0.692
1.662SerCys: 1.662 ± 0.433
3.436SerAsp: 3.436 ± 0.542
3.768SerGlu: 3.768 ± 0.5
1.662SerPhe: 1.662 ± 0.365
1.552SerGly: 1.552 ± 0.516
2.217SerHis: 2.217 ± 0.855
3.768SerIle: 3.768 ± 1.764
3.436SerLys: 3.436 ± 1.115
3.768SerLeu: 3.768 ± 1.757
1.441SerMet: 1.441 ± 0.701
4.766SerAsn: 4.766 ± 0.759
1.995SerPro: 1.995 ± 0.473
1.441SerGln: 1.441 ± 0.368
1.773SerArg: 1.773 ± 0.271
4.655SerSer: 4.655 ± 1.799
4.101SerThr: 4.101 ± 1.332
2.549SerVal: 2.549 ± 0.58
0.0SerTrp: 0.0 ± 0.0
4.655SerTyr: 4.655 ± 1.332
0.0SerXaa: 0.0 ± 0.0
Thr
4.433ThrAla: 4.433 ± 0.759
1.995ThrCys: 1.995 ± 0.417
3.657ThrAsp: 3.657 ± 0.421
2.66ThrGlu: 2.66 ± 0.486
2.217ThrPhe: 2.217 ± 0.264
3.546ThrGly: 3.546 ± 0.629
2.327ThrHis: 2.327 ± 0.539
7.315ThrIle: 7.315 ± 1.226
5.209ThrLys: 5.209 ± 0.422
8.534ThrLeu: 8.534 ± 0.78
1.995ThrMet: 1.995 ± 0.451
5.098ThrAsn: 5.098 ± 0.73
4.766ThrPro: 4.766 ± 0.476
2.882ThrGln: 2.882 ± 0.628
3.546ThrArg: 3.546 ± 0.288
5.098ThrSer: 5.098 ± 0.909
8.977ThrThr: 8.977 ± 1.176
4.433ThrVal: 4.433 ± 0.421
0.332ThrTrp: 0.332 ± 0.348
3.768ThrTyr: 3.768 ± 0.656
0.0ThrXaa: 0.0 ± 0.0
Val
2.882ValAla: 2.882 ± 0.365
1.552ValCys: 1.552 ± 0.287
2.327ValAsp: 2.327 ± 0.733
1.662ValGlu: 1.662 ± 0.548
2.992ValPhe: 2.992 ± 0.529
0.554ValGly: 0.554 ± 0.366
2.771ValHis: 2.771 ± 0.459
3.768ValIle: 3.768 ± 0.574
2.217ValLys: 2.217 ± 0.39
6.65ValLeu: 6.65 ± 0.852
0.997ValMet: 0.997 ± 0.329
4.544ValAsn: 4.544 ± 0.936
1.33ValPro: 1.33 ± 0.274
0.887ValGln: 0.887 ± 0.557
2.549ValArg: 2.549 ± 0.218
3.103ValSer: 3.103 ± 0.434
4.433ValThr: 4.433 ± 0.359
1.662ValVal: 1.662 ± 0.341
0.111ValTrp: 0.111 ± 0.064
3.879ValTyr: 3.879 ± 0.633
0.0ValXaa: 0.0 ± 0.0
Trp
0.443TrpAla: 0.443 ± 0.419
0.0TrpCys: 0.0 ± 0.0
0.554TrpAsp: 0.554 ± 0.377
0.0TrpGlu: 0.0 ± 0.0
0.111TrpPhe: 0.111 ± 0.367
0.111TrpGly: 0.111 ± 0.064
0.443TrpHis: 0.443 ± 0.395
0.554TrpIle: 0.554 ± 0.194
0.0TrpLys: 0.0 ± 0.0
0.887TrpLeu: 0.887 ± 0.154
0.111TrpMet: 0.111 ± 0.064
0.332TrpAsn: 0.332 ± 0.193
0.111TrpPro: 0.111 ± 0.228
0.0TrpGln: 0.0 ± 0.0
0.776TrpArg: 0.776 ± 0.283
0.332TrpSer: 0.332 ± 0.108
0.776TrpThr: 0.776 ± 0.263
0.222TrpVal: 0.222 ± 0.084
0.0TrpTrp: 0.0 ± 0.0
0.665TrpTyr: 0.665 ± 0.137
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.438TyrAla: 2.438 ± 0.424
1.884TyrCys: 1.884 ± 0.599
2.992TyrAsp: 2.992 ± 0.232
2.66TyrGlu: 2.66 ± 0.644
1.552TyrPhe: 1.552 ± 0.197
3.214TyrGly: 3.214 ± 0.731
2.66TyrHis: 2.66 ± 0.401
5.874TyrIle: 5.874 ± 0.341
3.103TyrLys: 3.103 ± 0.412
4.876TyrLeu: 4.876 ± 0.676
1.219TyrMet: 1.219 ± 0.395
7.315TyrAsn: 7.315 ± 1.393
1.773TyrPro: 1.773 ± 0.347
1.884TyrGln: 1.884 ± 0.324
2.771TyrArg: 2.771 ± 0.406
2.549TyrSer: 2.549 ± 0.464
6.317TyrThr: 6.317 ± 0.559
3.214TyrVal: 3.214 ± 0.426
0.554TyrTrp: 0.554 ± 0.583
3.546TyrTyr: 3.546 ± 0.902
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (9024 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski