Amino acid dipepetide frequency for Asian prunus virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.672AlaAla: 5.672 ± 1.5
1.063AlaCys: 1.063 ± 0.551
4.254AlaAsp: 4.254 ± 2.435
2.127AlaGlu: 2.127 ± 0.645
3.899AlaPhe: 3.899 ± 1.101
5.672AlaGly: 5.672 ± 2.138
1.772AlaHis: 1.772 ± 0.485
3.19AlaIle: 3.19 ± 1.997
6.381AlaLys: 6.381 ± 1.156
4.254AlaLeu: 4.254 ± 0.634
0.709AlaMet: 0.709 ± 0.642
4.254AlaAsn: 4.254 ± 2.204
1.063AlaPro: 1.063 ± 0.43
0.709AlaGln: 0.709 ± 1.214
3.899AlaArg: 3.899 ± 0.49
5.672AlaSer: 5.672 ± 3.394
2.836AlaThr: 2.836 ± 2.669
1.772AlaVal: 1.772 ± 0.7
0.354AlaTrp: 0.354 ± 0.184
0.354AlaTyr: 0.354 ± 0.184
0.0AlaXaa: 0.0 ± 0.0
Cys
1.772CysAla: 1.772 ± 1.333
0.0CysCys: 0.0 ± 0.0
0.354CysAsp: 0.354 ± 0.184
0.0CysGlu: 0.0 ± 0.0
1.418CysPhe: 1.418 ± 0.606
3.19CysGly: 3.19 ± 1.951
0.0CysHis: 0.0 ± 0.0
1.063CysIle: 1.063 ± 0.551
1.063CysLys: 1.063 ± 0.551
2.836CysLeu: 2.836 ± 1.278
0.354CysMet: 0.354 ± 0.184
1.063CysAsn: 1.063 ± 0.551
0.709CysPro: 0.709 ± 0.665
1.418CysGln: 1.418 ± 0.606
1.418CysArg: 1.418 ± 0.735
1.772CysSer: 1.772 ± 0.918
0.354CysThr: 0.354 ± 0.184
2.481CysVal: 2.481 ± 1.365
0.0CysTrp: 0.0 ± 0.0
1.772CysTyr: 1.772 ± 1.263
0.0CysXaa: 0.0 ± 0.0
Asp
2.127AspAla: 2.127 ± 2.078
1.772AspCys: 1.772 ± 0.656
0.709AspAsp: 0.709 ± 0.367
3.545AspGlu: 3.545 ± 0.474
3.19AspPhe: 3.19 ± 0.507
2.836AspGly: 2.836 ± 1.11
1.418AspHis: 1.418 ± 0.606
2.836AspIle: 2.836 ± 2.09
2.481AspLys: 2.481 ± 1.082
7.444AspLeu: 7.444 ± 1.474
1.063AspMet: 1.063 ± 0.423
2.836AspAsn: 2.836 ± 1.365
2.481AspPro: 2.481 ± 1.082
2.127AspGln: 2.127 ± 1.219
2.481AspArg: 2.481 ± 1.082
3.545AspSer: 3.545 ± 0.657
1.772AspThr: 1.772 ± 1.333
2.836AspVal: 2.836 ± 0.882
0.354AspTrp: 0.354 ± 0.184
1.772AspTyr: 1.772 ± 0.656
0.0AspXaa: 0.0 ± 0.0
Glu
6.026GluAla: 6.026 ± 1.037
0.354GluCys: 0.354 ± 0.184
4.963GluAsp: 4.963 ± 1.087
4.963GluGlu: 4.963 ± 1.464
2.836GluPhe: 2.836 ± 0.711
4.608GluGly: 4.608 ± 1.916
1.063GluHis: 1.063 ± 0.43
4.608GluIle: 4.608 ± 0.684
3.899GluLys: 3.899 ± 0.964
3.899GluLeu: 3.899 ± 1.008
1.063GluMet: 1.063 ± 0.43
2.481GluAsn: 2.481 ± 0.851
3.545GluPro: 3.545 ± 1.783
0.709GluGln: 0.709 ± 0.493
2.836GluArg: 2.836 ± 0.952
5.672GluSer: 5.672 ± 1.321
1.063GluThr: 1.063 ± 1.09
7.444GluVal: 7.444 ± 2.025
0.0GluTrp: 0.0 ± 0.0
1.418GluTyr: 1.418 ± 0.606
0.0GluXaa: 0.0 ± 0.0
Phe
4.963PheAla: 4.963 ± 0.991
2.127PheCys: 2.127 ± 0.749
3.545PheAsp: 3.545 ± 2.486
5.672PheGlu: 5.672 ± 0.776
2.836PhePhe: 2.836 ± 0.882
3.899PheGly: 3.899 ± 0.82
2.127PheHis: 2.127 ± 1.102
3.19PheIle: 3.19 ± 0.725
3.19PheLys: 3.19 ± 1.262
6.381PheLeu: 6.381 ± 2.719
0.354PheMet: 0.354 ± 0.184
1.772PheAsn: 1.772 ± 0.746
3.19PhePro: 3.19 ± 1.413
1.418PheGln: 1.418 ± 0.684
1.418PheArg: 1.418 ± 0.735
7.444PheSer: 7.444 ± 1.411
5.317PheThr: 5.317 ± 1.88
2.481PheVal: 2.481 ± 0.334
0.354PheTrp: 0.354 ± 0.184
0.709PheTyr: 0.709 ± 0.493
0.0PheXaa: 0.0 ± 0.0
Gly
2.836GlyAla: 2.836 ± 1.455
1.772GlyCys: 1.772 ± 1.096
4.608GlyAsp: 4.608 ± 1.48
3.899GlyGlu: 3.899 ± 1.426
2.127GlyPhe: 2.127 ± 0.645
1.418GlyGly: 1.418 ± 1.572
1.418GlyHis: 1.418 ± 0.735
3.19GlyIle: 3.19 ± 1.12
4.608GlyLys: 4.608 ± 1.741
6.026GlyLeu: 6.026 ± 2.286
0.709GlyMet: 0.709 ± 0.367
2.836GlyAsn: 2.836 ± 1.11
1.772GlyPro: 1.772 ± 1.183
2.127GlyGln: 2.127 ± 1.659
4.254GlyArg: 4.254 ± 1.322
6.026GlySer: 6.026 ± 0.744
3.545GlyThr: 3.545 ± 0.725
6.381GlyVal: 6.381 ± 1.302
0.709GlyTrp: 0.709 ± 0.493
1.772GlyTyr: 1.772 ± 0.485
0.0GlyXaa: 0.0 ± 0.0
His
0.709HisAla: 0.709 ± 0.698
0.709HisCys: 0.709 ± 0.665
1.063HisAsp: 1.063 ± 0.551
2.481HisGlu: 2.481 ± 0.851
0.709HisPhe: 0.709 ± 0.665
0.709HisGly: 0.709 ± 1.258
1.418HisHis: 1.418 ± 0.735
1.063HisIle: 1.063 ± 0.43
1.772HisLys: 1.772 ± 0.656
3.19HisLeu: 3.19 ± 1.653
0.354HisMet: 0.354 ± 0.9
0.709HisAsn: 0.709 ± 0.793
0.709HisPro: 0.709 ± 0.367
0.0HisGln: 0.0 ± 0.0
1.418HisArg: 1.418 ± 0.632
3.545HisSer: 3.545 ± 1.422
1.063HisThr: 1.063 ± 0.43
1.418HisVal: 1.418 ± 0.683
0.709HisTrp: 0.709 ± 0.793
1.418HisTyr: 1.418 ± 0.735
0.0HisXaa: 0.0 ± 0.0
Ile
2.127IleAla: 2.127 ± 1.751
1.063IleCys: 1.063 ± 0.666
2.481IleAsp: 2.481 ± 1.924
5.317IleGlu: 5.317 ± 0.7
3.19IlePhe: 3.19 ± 1.25
3.19IleGly: 3.19 ± 1.266
1.772IleHis: 1.772 ± 1.352
3.545IleIle: 3.545 ± 3.547
4.608IleLys: 4.608 ± 0.705
6.026IleLeu: 6.026 ± 2.176
1.418IleMet: 1.418 ± 0.441
1.772IleAsn: 1.772 ± 1.014
1.418IlePro: 1.418 ± 0.632
1.772IleGln: 1.772 ± 0.918
2.836IleArg: 2.836 ± 1.835
3.19IleSer: 3.19 ± 1.69
1.063IleThr: 1.063 ± 0.609
4.254IleVal: 4.254 ± 1.509
1.063IleTrp: 1.063 ± 0.666
1.772IleTyr: 1.772 ± 0.918
0.0IleXaa: 0.0 ± 0.0
Lys
3.899LysAla: 3.899 ± 1.286
0.0LysCys: 0.0 ± 0.0
2.127LysAsp: 2.127 ± 0.645
2.127LysGlu: 2.127 ± 0.374
3.899LysPhe: 3.899 ± 1.565
4.963LysGly: 4.963 ± 3.327
2.127LysHis: 2.127 ± 0.645
3.899LysIle: 3.899 ± 0.879
4.608LysLys: 4.608 ± 1.438
6.026LysLeu: 6.026 ± 1.482
1.063LysMet: 1.063 ± 0.551
4.254LysAsn: 4.254 ± 1.008
2.481LysPro: 2.481 ± 0.713
1.418LysGln: 1.418 ± 0.606
3.545LysArg: 3.545 ± 1.092
6.026LysSer: 6.026 ± 2.176
3.19LysThr: 3.19 ± 0.947
5.317LysVal: 5.317 ± 1.289
0.354LysTrp: 0.354 ± 0.184
1.772LysTyr: 1.772 ± 0.656
0.0LysXaa: 0.0 ± 0.0
Leu
3.545LeuAla: 3.545 ± 1.292
2.836LeuCys: 2.836 ± 1.013
6.381LeuAsp: 6.381 ± 1.554
5.672LeuGlu: 5.672 ± 1.905
6.735LeuPhe: 6.735 ± 2.234
6.381LeuGly: 6.381 ± 0.91
2.481LeuHis: 2.481 ± 0.713
5.317LeuIle: 5.317 ± 2.462
6.381LeuLys: 6.381 ± 0.813
5.672LeuLeu: 5.672 ± 2.326
1.418LeuMet: 1.418 ± 0.661
6.026LeuAsn: 6.026 ± 1.875
6.381LeuPro: 6.381 ± 2.047
3.19LeuGln: 3.19 ± 1.12
4.254LeuArg: 4.254 ± 0.917
9.571LeuSer: 9.571 ± 1.513
5.317LeuThr: 5.317 ± 1.214
7.444LeuVal: 7.444 ± 1.901
0.0LeuTrp: 0.0 ± 0.0
1.063LeuTyr: 1.063 ± 0.551
0.0LeuXaa: 0.0 ± 0.0
Met
2.836MetAla: 2.836 ± 1.469
0.709MetCys: 0.709 ± 0.367
1.418MetAsp: 1.418 ± 0.632
1.418MetGlu: 1.418 ± 0.441
1.063MetPhe: 1.063 ± 0.717
0.709MetGly: 0.709 ± 0.367
0.0MetHis: 0.0 ± 0.0
0.354MetIle: 0.354 ± 0.184
1.063MetLys: 1.063 ± 0.551
2.127MetLeu: 2.127 ± 0.761
0.709MetMet: 0.709 ± 0.53
1.063MetAsn: 1.063 ± 0.551
1.063MetPro: 1.063 ± 0.666
0.354MetGln: 0.354 ± 0.184
0.709MetArg: 0.709 ± 0.367
1.063MetSer: 1.063 ± 0.43
0.354MetThr: 0.354 ± 0.607
0.709MetVal: 0.709 ± 0.367
0.354MetTrp: 0.354 ± 0.607
0.354MetTyr: 0.354 ± 0.184
0.0MetXaa: 0.0 ± 0.0
Asn
1.772AsnAla: 1.772 ± 0.906
2.127AsnCys: 2.127 ± 0.76
0.354AsnAsp: 0.354 ± 0.184
2.481AsnGlu: 2.481 ± 1.286
3.545AsnPhe: 3.545 ± 1.837
2.836AsnGly: 2.836 ± 0.952
2.127AsnHis: 2.127 ± 0.761
3.19AsnIle: 3.19 ± 1.35
2.127AsnLys: 2.127 ± 0.645
8.508AsnLeu: 8.508 ± 1.966
0.709AsnMet: 0.709 ± 0.367
1.772AsnAsn: 1.772 ± 0.521
2.127AsnPro: 2.127 ± 1.102
1.772AsnGln: 1.772 ± 0.656
4.963AsnArg: 4.963 ± 1.939
3.545AsnSer: 3.545 ± 2.093
2.127AsnThr: 2.127 ± 0.59
1.063AsnVal: 1.063 ± 0.43
1.063AsnTrp: 1.063 ± 0.551
0.709AsnTyr: 0.709 ± 0.698
0.0AsnXaa: 0.0 ± 0.0
Pro
2.127ProAla: 2.127 ± 1.102
0.709ProCys: 0.709 ± 0.367
3.19ProAsp: 3.19 ± 1.305
4.608ProGlu: 4.608 ± 1.741
1.772ProPhe: 1.772 ± 0.906
2.481ProGly: 2.481 ± 1.286
1.063ProHis: 1.063 ± 1.285
3.19ProIle: 3.19 ± 2.136
1.418ProLys: 1.418 ± 0.744
2.481ProLeu: 2.481 ± 0.792
0.0ProMet: 0.0 ± 0.0
2.127ProAsn: 2.127 ± 0.927
4.963ProPro: 4.963 ± 3.886
1.772ProGln: 1.772 ± 0.746
1.418ProArg: 1.418 ± 0.985
4.963ProSer: 4.963 ± 2.004
1.772ProThr: 1.772 ± 0.918
2.481ProVal: 2.481 ± 1.394
1.418ProTrp: 1.418 ± 0.735
1.063ProTyr: 1.063 ± 0.609
0.0ProXaa: 0.0 ± 0.0
Gln
0.354GlnAla: 0.354 ± 0.184
0.0GlnCys: 0.0 ± 0.0
3.19GlnAsp: 3.19 ± 1.111
1.063GlnGlu: 1.063 ± 0.717
2.127GlnPhe: 2.127 ± 0.749
1.418GlnGly: 1.418 ± 0.441
0.354GlnHis: 0.354 ± 0.184
3.545GlnIle: 3.545 ± 1.806
1.418GlnLys: 1.418 ± 0.735
2.481GlnLeu: 2.481 ± 0.792
0.709GlnMet: 0.709 ± 0.367
1.418GlnAsn: 1.418 ± 0.735
0.709GlnPro: 0.709 ± 0.367
0.709GlnGln: 0.709 ± 0.493
1.418GlnArg: 1.418 ± 1.694
3.19GlnSer: 3.19 ± 0.755
1.772GlnThr: 1.772 ± 1.263
2.836GlnVal: 2.836 ± 2.166
0.0GlnTrp: 0.0 ± 0.0
0.709GlnTyr: 0.709 ± 0.367
0.0GlnXaa: 0.0 ± 0.0
Arg
3.545ArgAla: 3.545 ± 1.783
0.709ArgCys: 0.709 ± 0.367
3.19ArgAsp: 3.19 ± 1.12
3.19ArgGlu: 3.19 ± 0.915
4.963ArgPhe: 4.963 ± 1.342
1.772ArgGly: 1.772 ± 0.485
1.418ArgHis: 1.418 ± 1.331
1.418ArgIle: 1.418 ± 1.809
1.418ArgLys: 1.418 ± 0.735
5.317ArgLeu: 5.317 ± 0.987
1.063ArgMet: 1.063 ± 0.43
1.772ArgAsn: 1.772 ± 0.918
1.772ArgPro: 1.772 ± 0.646
1.418ArgGln: 1.418 ± 0.985
4.254ArgArg: 4.254 ± 1.163
6.026ArgSer: 6.026 ± 1.056
2.127ArgThr: 2.127 ± 0.374
3.899ArgVal: 3.899 ± 1.008
0.709ArgTrp: 0.709 ± 0.367
2.481ArgTyr: 2.481 ± 0.765
0.0ArgXaa: 0.0 ± 0.0
Ser
5.672SerAla: 5.672 ± 2.358
2.127SerCys: 2.127 ± 0.845
3.545SerAsp: 3.545 ± 0.971
4.254SerGlu: 4.254 ± 1.008
6.381SerPhe: 6.381 ± 1.554
6.735SerGly: 6.735 ± 1.861
1.772SerHis: 1.772 ± 0.746
3.545SerIle: 3.545 ± 1.326
7.09SerLys: 7.09 ± 2.224
6.026SerLeu: 6.026 ± 1.649
2.481SerMet: 2.481 ± 0.851
5.317SerAsn: 5.317 ± 0.456
4.608SerPro: 4.608 ± 0.842
3.545SerGln: 3.545 ± 1.275
3.545SerArg: 3.545 ± 1.275
7.09SerSer: 7.09 ± 1.661
7.444SerThr: 7.444 ± 3.626
5.317SerVal: 5.317 ± 1.541
0.354SerTrp: 0.354 ± 0.607
4.254SerTyr: 4.254 ± 1.763
0.0SerXaa: 0.0 ± 0.0
Thr
3.899ThrAla: 3.899 ± 3.12
1.418ThrCys: 1.418 ± 2.18
0.709ThrAsp: 0.709 ± 0.367
4.254ThrGlu: 4.254 ± 1.29
5.672ThrPhe: 5.672 ± 2.078
3.899ThrGly: 3.899 ± 1.158
0.709ThrHis: 0.709 ± 0.367
0.709ThrIle: 0.709 ± 0.367
2.127ThrLys: 2.127 ± 2.061
6.381ThrLeu: 6.381 ± 0.603
1.772ThrMet: 1.772 ± 0.672
1.418ThrAsn: 1.418 ± 0.441
1.063ThrPro: 1.063 ± 0.87
1.772ThrGln: 1.772 ± 0.918
2.481ThrArg: 2.481 ± 2.306
4.963ThrSer: 4.963 ± 5.273
3.545ThrThr: 3.545 ± 3.408
1.772ThrVal: 1.772 ± 0.918
0.0ThrTrp: 0.0 ± 0.0
1.418ThrTyr: 1.418 ± 0.606
0.0ThrXaa: 0.0 ± 0.0
Val
3.545ValAla: 3.545 ± 0.645
1.418ValCys: 1.418 ± 0.606
1.418ValAsp: 1.418 ± 0.606
3.899ValGlu: 3.899 ± 2.376
3.899ValPhe: 3.899 ± 0.8
3.899ValGly: 3.899 ± 1.584
1.063ValHis: 1.063 ± 0.609
2.836ValIle: 2.836 ± 1.005
4.963ValLys: 4.963 ± 1.38
7.444ValLeu: 7.444 ± 1.489
1.418ValMet: 1.418 ± 0.735
3.899ValAsn: 3.899 ± 1.158
4.254ValPro: 4.254 ± 0.568
2.481ValGln: 2.481 ± 1.394
3.19ValArg: 3.19 ± 0.527
5.317ValSer: 5.317 ± 1.218
3.899ValThr: 3.899 ± 1.656
6.735ValVal: 6.735 ± 3.141
0.354ValTrp: 0.354 ± 0.607
2.836ValTyr: 2.836 ± 1.474
0.0ValXaa: 0.0 ± 0.0
Trp
0.354TrpAla: 0.354 ± 0.184
0.709TrpCys: 0.709 ± 0.698
1.063TrpAsp: 1.063 ± 0.43
0.0TrpGlu: 0.0 ± 0.0
1.418TrpPhe: 1.418 ± 0.441
0.0TrpGly: 0.0 ± 0.0
0.354TrpHis: 0.354 ± 0.184
0.354TrpIle: 0.354 ± 0.184
0.0TrpLys: 0.0 ± 0.0
1.418TrpLeu: 1.418 ± 0.735
0.0TrpMet: 0.0 ± 0.0
1.063TrpAsn: 1.063 ± 1.093
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.354TrpSer: 0.354 ± 0.184
0.0TrpThr: 0.0 ± 0.0
1.063TrpVal: 1.063 ± 0.43
0.0TrpTrp: 0.0 ± 0.0
0.354TrpTyr: 0.354 ± 0.184
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.127TyrAla: 2.127 ± 0.645
1.418TyrCys: 1.418 ± 1.77
1.063TyrAsp: 1.063 ± 0.609
2.481TyrGlu: 2.481 ± 0.765
0.709TyrPhe: 0.709 ± 0.367
1.418TyrGly: 1.418 ± 0.606
0.709TyrHis: 0.709 ± 0.367
2.836TyrIle: 2.836 ± 1.212
2.481TyrLys: 2.481 ± 1.952
2.481TyrLeu: 2.481 ± 1.365
0.709TyrMet: 0.709 ± 0.367
1.063TyrAsn: 1.063 ± 0.551
0.709TyrPro: 0.709 ± 0.367
0.709TyrGln: 0.709 ± 0.665
2.127TyrArg: 2.127 ± 1.102
2.127TyrSer: 2.127 ± 0.645
1.418TyrThr: 1.418 ± 1.117
1.063TyrVal: 1.063 ± 0.551
0.354TyrTrp: 0.354 ± 0.184
0.709TyrTyr: 0.709 ± 0.367
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2822 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski