Amino acid dipepetide frequency for Youngiibacter fragilis 232.1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.362AlaAla: 7.362 ± 0.117	0.864AlaCys: 0.864 ± 0.033	4.043AlaAsp: 4.043 ± 0.084	5.158AlaGlu: 5.158 ± 0.076	3.238AlaPhe: 3.238 ± 0.06	6.312AlaGly: 6.312 ± 0.127	1.024AlaHis: 1.024 ± 0.028	5.87AlaIle: 5.87 ± 0.072	4.662AlaLys: 4.662 ± 0.061	7.429AlaLeu: 7.429 ± 0.091	2.639AlaMet: 2.639 ± 0.054	2.386AlaAsn: 2.386 ± 0.055	2.024AlaPro: 2.024 ± 0.053	1.626AlaGln: 1.626 ± 0.036	3.618AlaArg: 3.618 ± 0.061	4.728AlaSer: 4.728 ± 0.086	3.386AlaThr: 3.386 ± 0.061	6.034AlaVal: 6.034 ± 0.087	0.536AlaTrp: 0.536 ± 0.024	2.67AlaTyr: 2.67 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.621CysAla: 0.621 ± 0.021	0.133CysCys: 0.133 ± 0.012	0.616CysAsp: 0.616 ± 0.021	0.65CysGlu: 0.65 ± 0.027	0.357CysPhe: 0.357 ± 0.018	1.042CysGly: 1.042 ± 0.04	0.268CysHis: 0.268 ± 0.015	0.758CysIle: 0.758 ± 0.027	0.461CysLys: 0.461 ± 0.022	0.798CysLeu: 0.798 ± 0.03	0.311CysMet: 0.311 ± 0.015	0.395CysAsn: 0.395 ± 0.019	0.502CysPro: 0.502 ± 0.024	0.258CysGln: 0.258 ± 0.016	0.581CysArg: 0.581 ± 0.022	0.725CysSer: 0.725 ± 0.028	0.552CysThr: 0.552 ± 0.022	0.532CysVal: 0.532 ± 0.024	0.066CysTrp: 0.066 ± 0.007	0.322CysTyr: 0.322 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.991AspAla: 3.991 ± 0.072	0.569AspCys: 0.569 ± 0.023	2.963AspAsp: 2.963 ± 0.072	4.792AspGlu: 4.792 ± 0.076	2.73AspPhe: 2.73 ± 0.049	4.412AspGly: 4.412 ± 0.084	0.901AspHis: 0.901 ± 0.028	5.042AspIle: 5.042 ± 0.067	3.679AspLys: 3.679 ± 0.063	5.333AspLeu: 5.333 ± 0.066	1.891AspMet: 1.891 ± 0.043	2.051AspAsn: 2.051 ± 0.056	2.184AspPro: 2.184 ± 0.043	1.008AspGln: 1.008 ± 0.028	3.13AspArg: 3.13 ± 0.062	3.636AspSer: 3.636 ± 0.058	2.929AspThr: 2.929 ± 0.054	3.87AspVal: 3.87 ± 0.069	0.497AspTrp: 0.497 ± 0.022	2.234AspTyr: 2.234 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	5.667GluAla: 5.667 ± 0.082	0.61GluCys: 0.61 ± 0.026	4.219GluAsp: 4.219 ± 0.072	6.139GluGlu: 6.139 ± 0.106	2.68GluPhe: 2.68 ± 0.054	5.213GluGly: 5.213 ± 0.074	1.063GluHis: 1.063 ± 0.032	5.659GluIle: 5.659 ± 0.087	6.057GluLys: 6.057 ± 0.095	6.91GluLeu: 6.91 ± 0.115	2.378GluMet: 2.378 ± 0.052	3.471GluAsn: 3.471 ± 0.06	1.929GluPro: 1.929 ± 0.047	1.574GluGln: 1.574 ± 0.044	3.665GluArg: 3.665 ± 0.074	4.125GluSer: 4.125 ± 0.058	3.466GluThr: 3.466 ± 0.054	5.059GluVal: 5.059 ± 0.08	0.54GluTrp: 0.54 ± 0.025	2.725GluTyr: 2.725 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	2.859PheAla: 2.859 ± 0.058	0.471PheCys: 0.471 ± 0.021	2.585PheAsp: 2.585 ± 0.05	2.717PheGlu: 2.717 ± 0.044	1.793PhePhe: 1.793 ± 0.045	3.59PheGly: 3.59 ± 0.062	0.705PheHis: 0.705 ± 0.022	3.266PheIle: 3.266 ± 0.064	2.298PheLys: 2.298 ± 0.05	3.803PheLeu: 3.803 ± 0.075	1.359PheMet: 1.359 ± 0.038	1.793PheAsn: 1.793 ± 0.041	1.353PhePro: 1.353 ± 0.038	0.925PheGln: 0.925 ± 0.03	2.229PheArg: 2.229 ± 0.057	3.056PheSer: 3.056 ± 0.056	2.429PheThr: 2.429 ± 0.051	2.617PheVal: 2.617 ± 0.049	0.328PheTrp: 0.328 ± 0.016	1.428PheTyr: 1.428 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	5.687GlyAla: 5.687 ± 0.117	0.971GlyCys: 0.971 ± 0.033	3.963GlyAsp: 3.963 ± 0.087	4.767GlyGlu: 4.767 ± 0.074	3.694GlyPhe: 3.694 ± 0.062	5.759GlyGly: 5.759 ± 0.142	1.275GlyHis: 1.275 ± 0.038	7.183GlyIle: 7.183 ± 0.088	5.691GlyLys: 5.691 ± 0.077	6.95GlyLeu: 6.95 ± 0.087	2.741GlyMet: 2.741 ± 0.054	3.16GlyAsn: 3.16 ± 0.057	1.739GlyPro: 1.739 ± 0.038	1.658GlyGln: 1.658 ± 0.039	3.85GlyArg: 3.85 ± 0.067	5.021GlySer: 5.021 ± 0.094	4.773GlyThr: 4.773 ± 0.097	5.32GlyVal: 5.32 ± 0.066	0.693GlyTrp: 0.693 ± 0.025	3.287GlyTyr: 3.287 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.014HisAla: 1.014 ± 0.034	0.208HisCys: 0.208 ± 0.012	0.932HisAsp: 0.932 ± 0.03	1.126HisGlu: 1.126 ± 0.034	0.74HisPhe: 0.74 ± 0.028	1.37HisGly: 1.37 ± 0.038	0.401HisHis: 0.401 ± 0.02	1.264HisIle: 1.264 ± 0.031	0.88HisLys: 0.88 ± 0.022	1.441HisLeu: 1.441 ± 0.042	0.533HisMet: 0.533 ± 0.024	0.61HisAsn: 0.61 ± 0.024	0.831HisPro: 0.831 ± 0.029	0.384HisGln: 0.384 ± 0.019	0.84HisArg: 0.84 ± 0.028	1.084HisSer: 1.084 ± 0.034	0.761HisThr: 0.761 ± 0.027	1.056HisVal: 1.056 ± 0.027	0.152HisTrp: 0.152 ± 0.013	0.634HisTyr: 0.634 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.423IleAla: 6.423 ± 0.096	0.819IleCys: 0.819 ± 0.032	4.413IleAsp: 4.413 ± 0.062	5.398IleGlu: 5.398 ± 0.069	3.014IlePhe: 3.014 ± 0.051	5.94IleGly: 5.94 ± 0.081	1.249IleHis: 1.249 ± 0.034	5.446IleIle: 5.446 ± 0.084	4.14IleLys: 4.14 ± 0.066	7.273IleLeu: 7.273 ± 0.103	2.299IleMet: 2.299 ± 0.049	2.819IleAsn: 2.819 ± 0.061	3.386IlePro: 3.386 ± 0.054	1.608IleGln: 1.608 ± 0.04	4.424IleArg: 4.424 ± 0.072	5.617IleSer: 5.617 ± 0.077	4.307IleThr: 4.307 ± 0.063	5.198IleVal: 5.198 ± 0.076	0.505IleTrp: 0.505 ± 0.023	2.394IleTyr: 2.394 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.646LysAla: 5.646 ± 0.076	0.489LysCys: 0.489 ± 0.021	4.545LysAsp: 4.545 ± 0.069	5.617LysGlu: 5.617 ± 0.095	2.059LysPhe: 2.059 ± 0.045	5.218LysGly: 5.218 ± 0.075	0.975LysHis: 0.975 ± 0.03	4.141LysIle: 4.141 ± 0.065	4.767LysLys: 4.767 ± 0.081	5.593LysLeu: 5.593 ± 0.087	1.887LysMet: 1.887 ± 0.047	2.863LysAsn: 2.863 ± 0.051	2.133LysPro: 2.133 ± 0.047	1.378LysGln: 1.378 ± 0.038	3.107LysArg: 3.107 ± 0.058	3.979LysSer: 3.979 ± 0.068	3.332LysThr: 3.332 ± 0.061	4.999LysVal: 4.999 ± 0.079	0.511LysTrp: 0.511 ± 0.022	2.503LysTyr: 2.503 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	6.96LeuAla: 6.96 ± 0.08	0.848LeuCys: 0.848 ± 0.028	5.655LeuAsp: 5.655 ± 0.069	6.817LeuGlu: 6.817 ± 0.089	3.695LeuPhe: 3.695 ± 0.069	7.114LeuGly: 7.114 ± 0.084	1.392LeuHis: 1.392 ± 0.037	6.565LeuIle: 6.565 ± 0.097	6.88LeuLys: 6.88 ± 0.087	8.312LeuLeu: 8.312 ± 0.108	3.084LeuMet: 3.084 ± 0.054	3.651LeuAsn: 3.651 ± 0.064	3.432LeuPro: 3.432 ± 0.056	2.175LeuGln: 2.175 ± 0.04	4.487LeuArg: 4.487 ± 0.072	6.94LeuSer: 6.94 ± 0.078	4.972LeuThr: 4.972 ± 0.067	6.356LeuVal: 6.356 ± 0.076	0.6LeuTrp: 0.6 ± 0.024	3.026LeuTyr: 3.026 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.62MetAla: 2.62 ± 0.052	0.201MetCys: 0.201 ± 0.014	2.106MetAsp: 2.106 ± 0.05	2.601MetGlu: 2.601 ± 0.049	1.129MetPhe: 1.129 ± 0.036	2.526MetGly: 2.526 ± 0.049	0.479MetHis: 0.479 ± 0.022	2.118MetIle: 2.118 ± 0.046	2.716MetLys: 2.716 ± 0.054	2.83MetLeu: 2.83 ± 0.054	0.947MetMet: 0.947 ± 0.036	1.471MetAsn: 1.471 ± 0.04	1.162MetPro: 1.162 ± 0.032	0.74MetGln: 0.74 ± 0.026	1.429MetArg: 1.429 ± 0.038	1.943MetSer: 1.943 ± 0.045	1.789MetThr: 1.789 ± 0.036	2.366MetVal: 2.366 ± 0.047	0.166MetTrp: 0.166 ± 0.012	0.804MetTyr: 0.804 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	2.858AsnAla: 2.858 ± 0.057	0.432AsnCys: 0.432 ± 0.017	1.976AsnAsp: 1.976 ± 0.046	2.678AsnGlu: 2.678 ± 0.047	1.574AsnPhe: 1.574 ± 0.038	3.242AsnGly: 3.242 ± 0.058	0.725AsnHis: 0.725 ± 0.025	3.356AsnIle: 3.356 ± 0.058	2.225AsnLys: 2.225 ± 0.049	3.878AsnLeu: 3.878 ± 0.062	1.236AsnMet: 1.236 ± 0.033	1.548AsnAsn: 1.548 ± 0.04	2.062AsnPro: 2.062 ± 0.043	1.052AsnGln: 1.052 ± 0.032	2.004AsnArg: 2.004 ± 0.042	2.496AsnSer: 2.496 ± 0.053	2.06AsnThr: 2.06 ± 0.048	2.771AsnVal: 2.771 ± 0.056	0.331AsnTrp: 0.331 ± 0.017	1.426AsnTyr: 1.426 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	2.394ProAla: 2.394 ± 0.056	0.318ProCys: 0.318 ± 0.018	2.282ProAsp: 2.282 ± 0.054	3.272ProGlu: 3.272 ± 0.054	1.538ProPhe: 1.538 ± 0.036	2.759ProGly: 2.759 ± 0.049	0.627ProHis: 0.627 ± 0.027	2.258ProIle: 2.258 ± 0.049	1.959ProLys: 1.959 ± 0.045	3.055ProLeu: 3.055 ± 0.058	1.074ProMet: 1.074 ± 0.029	1.191ProAsn: 1.191 ± 0.031	0.902ProPro: 0.902 ± 0.027	0.892ProGln: 0.892 ± 0.031	1.232ProArg: 1.232 ± 0.036	2.132ProSer: 2.132 ± 0.044	1.692ProThr: 1.692 ± 0.05	3.179ProVal: 3.179 ± 0.06	0.313ProTrp: 0.313 ± 0.016	1.358ProTyr: 1.358 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	1.718GlnAla: 1.718 ± 0.046	0.188GlnCys: 0.188 ± 0.012	1.191GlnAsp: 1.191 ± 0.031	1.647GlnGlu: 1.647 ± 0.04	0.857GlnPhe: 0.857 ± 0.029	1.659GlnGly: 1.659 ± 0.034	0.383GlnHis: 0.383 ± 0.017	1.639GlnIle: 1.639 ± 0.039	1.65GlnLys: 1.65 ± 0.042	2.022GlnLeu: 2.022 ± 0.043	0.802GlnMet: 0.802 ± 0.028	1.068GlnAsn: 1.068 ± 0.033	0.718GlnPro: 0.718 ± 0.028	0.589GlnGln: 0.589 ± 0.023	1.133GlnArg: 1.133 ± 0.036	1.327GlnSer: 1.327 ± 0.037	1.136GlnThr: 1.136 ± 0.033	1.669GlnVal: 1.669 ± 0.036	0.199GlnTrp: 0.199 ± 0.013	0.828GlnTyr: 0.828 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.81ArgAla: 2.81 ± 0.06	0.47ArgCys: 0.47 ± 0.024	2.93ArgAsp: 2.93 ± 0.055	4.215ArgGlu: 4.215 ± 0.089	2.119ArgPhe: 2.119 ± 0.045	2.933ArgGly: 2.933 ± 0.056	0.852ArgHis: 0.852 ± 0.028	4.371ArgIle: 4.371 ± 0.069	4.032ArgLys: 4.032 ± 0.068	4.828ArgLeu: 4.828 ± 0.079	1.77ArgMet: 1.77 ± 0.043	2.527ArgAsn: 2.527 ± 0.05	1.36ArgPro: 1.36 ± 0.04	1.372ArgGln: 1.372 ± 0.043	2.635ArgArg: 2.635 ± 0.053	2.815ArgSer: 2.815 ± 0.06	2.596ArgThr: 2.596 ± 0.051	3.163ArgVal: 3.163 ± 0.06	0.401ArgTrp: 0.401 ± 0.02	2.03ArgTyr: 2.03 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	4.595SerAla: 4.595 ± 0.083	0.597SerCys: 0.597 ± 0.02	3.649SerAsp: 3.649 ± 0.062	4.472SerGlu: 4.472 ± 0.065	3.102SerPhe: 3.102 ± 0.055	5.904SerGly: 5.904 ± 0.093	1.151SerHis: 1.151 ± 0.036	5.04SerIle: 5.04 ± 0.072	3.864SerLys: 3.864 ± 0.056	6.351SerLeu: 6.351 ± 0.09	2.212SerMet: 2.212 ± 0.044	2.329SerAsn: 2.329 ± 0.05	2.145SerPro: 2.145 ± 0.042	1.524SerGln: 1.524 ± 0.039	3.304SerArg: 3.304 ± 0.058	4.234SerSer: 4.234 ± 0.075	3.168SerThr: 3.168 ± 0.067	4.67SerVal: 4.67 ± 0.074	0.57SerTrp: 0.57 ± 0.023	2.436SerTyr: 2.436 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	4.298ThrAla: 4.298 ± 0.096	0.463ThrCys: 0.463 ± 0.021	3.05ThrAsp: 3.05 ± 0.052	3.499ThrGlu: 3.499 ± 0.058	2.219ThrPhe: 2.219 ± 0.045	5.092ThrGly: 5.092 ± 0.083	0.842ThrHis: 0.842 ± 0.027	3.915ThrIle: 3.915 ± 0.069	2.771ThrLys: 2.771 ± 0.049	4.882ThrLeu: 4.882 ± 0.077	1.539ThrMet: 1.539 ± 0.037	1.765ThrAsn: 1.765 ± 0.039	2.187ThrPro: 2.187 ± 0.049	1.009ThrGln: 1.009 ± 0.035	2.445ThrArg: 2.445 ± 0.045	3.227ThrSer: 3.227 ± 0.067	2.716ThrThr: 2.716 ± 0.053	4.26ThrVal: 4.26 ± 0.073	0.469ThrTrp: 0.469 ± 0.024	1.935ThrTyr: 1.935 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	5.045ValAla: 5.045 ± 0.067	0.746ValCys: 0.746 ± 0.026	3.995ValAsp: 3.995 ± 0.052	4.624ValGlu: 4.624 ± 0.081	3.066ValPhe: 3.066 ± 0.056	4.528ValGly: 4.528 ± 0.075	1.166ValHis: 1.166 ± 0.036	5.744ValIle: 5.744 ± 0.08	4.46ValLys: 4.46 ± 0.067	6.991ValLeu: 6.991 ± 0.085	2.166ValMet: 2.166 ± 0.043	2.948ValAsn: 2.948 ± 0.055	2.82ValPro: 2.82 ± 0.054	1.51ValGln: 1.51 ± 0.039	3.659ValArg: 3.659 ± 0.065	5.166ValSer: 5.166 ± 0.087	4.262ValThr: 4.262 ± 0.086	5.29ValVal: 5.29 ± 0.072	0.541ValTrp: 0.541 ± 0.022	2.387ValTyr: 2.387 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.505TrpAla: 0.505 ± 0.022	0.102TrpCys: 0.102 ± 0.01	0.46TrpAsp: 0.46 ± 0.02	0.517TrpGlu: 0.517 ± 0.022	0.404TrpPhe: 0.404 ± 0.02	0.581TrpGly: 0.581 ± 0.024	0.157TrpHis: 0.157 ± 0.012	0.543TrpIle: 0.543 ± 0.026	0.561TrpLys: 0.561 ± 0.023	0.73TrpLeu: 0.73 ± 0.028	0.232TrpMet: 0.232 ± 0.014	0.435TrpAsn: 0.435 ± 0.022	0.221TrpPro: 0.221 ± 0.015	0.253TrpGln: 0.253 ± 0.015	0.357TrpArg: 0.357 ± 0.019	0.455TrpSer: 0.455 ± 0.02	0.434TrpThr: 0.434 ± 0.021	0.442TrpVal: 0.442 ± 0.024	0.093TrpTrp: 0.093 ± 0.009	0.306TrpTyr: 0.306 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.537TyrAla: 2.537 ± 0.054	0.449TyrCys: 0.449 ± 0.019	2.269TyrAsp: 2.269 ± 0.046	2.443TyrGlu: 2.443 ± 0.051	1.597TyrPhe: 1.597 ± 0.04	2.988TyrGly: 2.988 ± 0.053	0.624TyrHis: 0.624 ± 0.026	2.494TyrIle: 2.494 ± 0.053	1.991TyrLys: 1.991 ± 0.044	3.548TyrLeu: 3.548 ± 0.06	1.04TyrMet: 1.04 ± 0.036	1.446TyrAsn: 1.446 ± 0.038	1.335TyrPro: 1.335 ± 0.037	0.886TyrGln: 0.886 ± 0.026	2.103TyrArg: 2.103 ± 0.046	2.614TyrSer: 2.614 ± 0.055	1.823TyrThr: 1.823 ± 0.049	2.267TyrVal: 2.267 ± 0.045	0.277TyrTrp: 0.277 ± 0.018	1.347TyrTyr: 1.347 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3729 proteins (1132455 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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