Amino acid dipepetide frequency for Eimeria brunetti

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	88.143AlaAla: 88.143 ± 0.946	1.512AlaCys: 1.512 ± 0.023	4.831AlaAsp: 4.831 ± 0.056	7.738AlaGlu: 7.738 ± 0.062	2.395AlaPhe: 2.395 ± 0.025	8.158AlaGly: 8.158 ± 0.063	1.334AlaHis: 1.334 ± 0.019	2.027AlaIle: 2.027 ± 0.022	3.222AlaLys: 3.222 ± 0.041	7.849AlaLeu: 7.849 ± 0.065	1.072AlaMet: 1.072 ± 0.019	1.952AlaAsn: 1.952 ± 0.024	7.6AlaPro: 7.6 ± 0.076	3.389AlaGln: 3.389 ± 0.034	4.277AlaArg: 4.277 ± 0.032	6.898AlaSer: 6.898 ± 0.049	7.552AlaThr: 7.552 ± 0.067	6.341AlaVal: 6.341 ± 0.052	0.691AlaTrp: 0.691 ± 0.014	1.225AlaTyr: 1.225 ± 0.018	0.005AlaXaa: 0.005 ± 0.001
Cys	1.136CysAla: 1.136 ± 0.018	1.758CysCys: 1.758 ± 0.04	0.442CysAsp: 0.442 ± 0.012	0.607CysGlu: 0.607 ± 0.014	0.615CysPhe: 0.615 ± 0.013	1.056CysGly: 1.056 ± 0.019	0.229CysHis: 0.229 ± 0.008	0.633CysIle: 0.633 ± 0.014	0.476CysLys: 0.476 ± 0.013	1.898CysLeu: 1.898 ± 0.025	0.427CysMet: 0.427 ± 0.011	0.39CysAsn: 0.39 ± 0.01	0.79CysPro: 0.79 ± 0.03	0.399CysGln: 0.399 ± 0.01	1.033CysArg: 1.033 ± 0.016	2.825CysSer: 2.825 ± 0.033	0.723CysThr: 0.723 ± 0.014	0.795CysVal: 0.795 ± 0.014	0.243CysTrp: 0.243 ± 0.009	0.267CysTyr: 0.267 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.316AspAla: 4.316 ± 0.052	0.693AspCys: 0.693 ± 0.014	1.844AspAsp: 1.844 ± 0.044	2.514AspGlu: 2.514 ± 0.033	1.045AspPhe: 1.045 ± 0.018	2.471AspGly: 2.471 ± 0.033	0.421AspHis: 0.421 ± 0.012	1.227AspIle: 1.227 ± 0.022	1.548AspLys: 1.548 ± 0.032	2.765AspLeu: 2.765 ± 0.033	0.601AspMet: 0.601 ± 0.014	0.761AspAsn: 0.761 ± 0.018	2.123AspPro: 2.123 ± 0.029	1.025AspGln: 1.025 ± 0.022	2.279AspArg: 2.279 ± 0.044	3.302AspSer: 3.302 ± 0.038	1.874AspThr: 1.874 ± 0.026	1.669AspVal: 1.669 ± 0.02	0.403AspTrp: 0.403 ± 0.01	0.576AspTyr: 0.576 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	7.843GluAla: 7.843 ± 0.063	0.623GluCys: 0.623 ± 0.018	2.592GluAsp: 2.592 ± 0.036	7.111GluGlu: 7.111 ± 0.103	1.071GluPhe: 1.071 ± 0.016	5.186GluGly: 5.186 ± 0.049	0.744GluHis: 0.744 ± 0.015	1.504GluIle: 1.504 ± 0.025	3.341GluLys: 3.341 ± 0.067	4.363GluLeu: 4.363 ± 0.044	0.932GluMet: 0.932 ± 0.02	1.247GluAsn: 1.247 ± 0.023	2.181GluPro: 2.181 ± 0.03	5.54GluGln: 5.54 ± 0.072	3.409GluArg: 3.409 ± 0.051	2.564GluSer: 2.564 ± 0.032	5.012GluThr: 5.012 ± 0.093	2.536GluVal: 2.536 ± 0.029	0.496GluTrp: 0.496 ± 0.011	0.72GluTyr: 0.72 ± 0.013	0.001GluXaa: 0.001 ± 0.0
Phe	2.324PheAla: 2.324 ± 0.025	0.674PheCys: 0.674 ± 0.011	0.976PheAsp: 0.976 ± 0.018	1.222PheGlu: 1.222 ± 0.017	1.025PhePhe: 1.025 ± 0.019	1.379PheGly: 1.379 ± 0.023	0.421PheHis: 0.421 ± 0.01	0.835PheIle: 0.835 ± 0.017	0.816PheLys: 0.816 ± 0.015	2.57PheLeu: 2.57 ± 0.026	0.37PheMet: 0.37 ± 0.008	0.594PheAsn: 0.594 ± 0.013	1.209PhePro: 1.209 ± 0.017	0.761PheGln: 0.761 ± 0.014	1.204PheArg: 1.204 ± 0.018	2.201PheSer: 2.201 ± 0.022	0.909PheThr: 0.909 ± 0.016	1.58PheVal: 1.58 ± 0.021	0.254PheTrp: 0.254 ± 0.007	0.514PheTyr: 0.514 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	8.127GlyAla: 8.127 ± 0.068	1.182GlyCys: 1.182 ± 0.017	3.798GlyAsp: 3.798 ± 0.058	3.765GlyGlu: 3.765 ± 0.04	1.602GlyPhe: 1.602 ± 0.023	6.942GlyGly: 6.942 ± 0.073	0.817GlyHis: 0.817 ± 0.017	1.498GlyIle: 1.498 ± 0.023	2.118GlyLys: 2.118 ± 0.03	4.608GlyLeu: 4.608 ± 0.043	0.773GlyMet: 0.773 ± 0.014	1.218GlyAsn: 1.218 ± 0.022	4.814GlyPro: 4.814 ± 0.081	2.025GlyGln: 2.025 ± 0.03	3.439GlyArg: 3.439 ± 0.031	5.846GlySer: 5.846 ± 0.054	2.6GlyThr: 2.6 ± 0.033	3.141GlyVal: 3.141 ± 0.028	0.616GlyTrp: 0.616 ± 0.012	0.867GlyTyr: 0.867 ± 0.015	0.001GlyXaa: 0.001 ± 0.0
His	1.895HisAla: 1.895 ± 0.025	0.374HisCys: 0.374 ± 0.009	0.547HisAsp: 0.547 ± 0.015	1.039HisGlu: 1.039 ± 0.02	0.551HisPhe: 0.551 ± 0.01	0.958HisGly: 0.958 ± 0.018	1.095HisHis: 1.095 ± 0.031	0.542HisIle: 0.542 ± 0.011	0.747HisLys: 0.747 ± 0.015	2.122HisLeu: 2.122 ± 0.026	0.366HisMet: 0.366 ± 0.011	0.397HisAsn: 0.397 ± 0.011	1.422HisPro: 1.422 ± 0.021	2.506HisGln: 2.506 ± 0.047	1.431HisArg: 1.431 ± 0.018	1.417HisSer: 1.417 ± 0.022	0.767HisThr: 0.767 ± 0.015	0.79HisVal: 0.79 ± 0.015	0.231HisTrp: 0.231 ± 0.007	0.366HisTyr: 0.366 ± 0.011	0.001HisXaa: 0.001 ± 0.0
Ile	2.058IleAla: 2.058 ± 0.025	0.648IleCys: 0.648 ± 0.014	1.066IleAsp: 1.066 ± 0.018	1.494IleGlu: 1.494 ± 0.02	0.771IlePhe: 0.771 ± 0.013	1.335IleGly: 1.335 ± 0.019	0.574IleHis: 0.574 ± 0.011	0.845IleIle: 0.845 ± 0.026	1.047IleLys: 1.047 ± 0.019	1.938IleLeu: 1.938 ± 0.023	0.374IleMet: 0.374 ± 0.012	0.707IleAsn: 0.707 ± 0.016	1.302IlePro: 1.302 ± 0.024	1.093IleGln: 1.093 ± 0.018	1.441IleArg: 1.441 ± 0.02	2.069IleSer: 2.069 ± 0.028	0.986IleThr: 0.986 ± 0.02	1.194IleVal: 1.194 ± 0.02	0.243IleTrp: 0.243 ± 0.007	0.452IleTyr: 0.452 ± 0.011	0.001IleXaa: 0.001 ± 0.0
Lys	3.313LysAla: 3.313 ± 0.035	0.439LysCys: 0.439 ± 0.011	1.343LysAsp: 1.343 ± 0.028	4.49LysGlu: 4.49 ± 0.097	0.617LysPhe: 0.617 ± 0.013	3.154LysGly: 3.154 ± 0.045	0.697LysHis: 0.697 ± 0.014	0.933LysIle: 0.933 ± 0.017	2.641LysLys: 2.641 ± 0.06	2.563LysLeu: 2.563 ± 0.028	0.582LysMet: 0.582 ± 0.013	0.913LysAsn: 0.913 ± 0.016	1.634LysPro: 1.634 ± 0.028	3.557LysGln: 3.557 ± 0.04	2.764LysArg: 2.764 ± 0.034	1.697LysSer: 1.697 ± 0.022	1.703LysThr: 1.703 ± 0.025	1.377LysVal: 1.377 ± 0.023	0.313LysTrp: 0.313 ± 0.01	0.547LysTyr: 0.547 ± 0.013	0.001LysXaa: 0.001 ± 0.0
Leu	6.43LeuAla: 6.43 ± 0.052	1.515LeuCys: 1.515 ± 0.019	2.62LeuAsp: 2.62 ± 0.032	4.317LeuGlu: 4.317 ± 0.046	2.353LeuPhe: 2.353 ± 0.032	4.246LeuGly: 4.246 ± 0.038	2.376LeuHis: 2.376 ± 0.023	1.797LeuIle: 1.797 ± 0.023	3.104LeuLys: 3.104 ± 0.031	17.561LeuLeu: 17.561 ± 0.179	1.225LeuMet: 1.225 ± 0.019	1.657LeuAsn: 1.657 ± 0.026	5.823LeuPro: 5.823 ± 0.044	13.163LeuGln: 13.163 ± 0.151	5.815LeuArg: 5.815 ± 0.047	5.973LeuSer: 5.973 ± 0.049	2.811LeuThr: 2.811 ± 0.03	3.512LeuVal: 3.512 ± 0.041	0.894LeuTrp: 0.894 ± 0.017	1.362LeuTyr: 1.362 ± 0.016	0.001LeuXaa: 0.001 ± 0.0
Met	1.08MetAla: 1.08 ± 0.016	0.156MetCys: 0.156 ± 0.006	0.5MetAsp: 0.5 ± 0.011	0.946MetGlu: 0.946 ± 0.019	0.303MetPhe: 0.303 ± 0.01	0.959MetGly: 0.959 ± 0.018	0.454MetHis: 0.454 ± 0.01	0.299MetIle: 0.299 ± 0.009	0.609MetLys: 0.609 ± 0.015	1.426MetLeu: 1.426 ± 0.02	0.283MetMet: 0.283 ± 0.014	0.312MetAsn: 0.312 ± 0.009	0.691MetPro: 0.691 ± 0.015	1.632MetGln: 1.632 ± 0.029	0.977MetArg: 0.977 ± 0.016	0.704MetSer: 0.704 ± 0.013	0.536MetThr: 0.536 ± 0.012	0.569MetVal: 0.569 ± 0.013	0.145MetTrp: 0.145 ± 0.006	0.233MetTyr: 0.233 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	1.896AsnAla: 1.896 ± 0.025	0.51AsnCys: 0.51 ± 0.013	0.744AsnAsp: 0.744 ± 0.017	1.131AsnGlu: 1.131 ± 0.021	0.563AsnPhe: 0.563 ± 0.011	1.485AsnGly: 1.485 ± 0.025	0.332AsnHis: 0.332 ± 0.009	0.781AsnIle: 0.781 ± 0.016	1.076AsnLys: 1.076 ± 0.019	1.481AsnLeu: 1.481 ± 0.021	0.362AsnMet: 0.362 ± 0.01	1.041AsnAsn: 1.041 ± 0.032	1.344AsnPro: 1.344 ± 0.019	0.741AsnGln: 0.741 ± 0.015	1.205AsnArg: 1.205 ± 0.021	3.765AsnSer: 3.765 ± 0.051	1.078AsnThr: 1.078 ± 0.018	0.861AsnVal: 0.861 ± 0.016	0.214AsnTrp: 0.214 ± 0.007	0.379AsnTyr: 0.379 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	8.196ProAla: 8.196 ± 0.075	0.851ProCys: 0.851 ± 0.019	1.648ProAsp: 1.648 ± 0.025	2.76ProGlu: 2.76 ± 0.035	1.719ProPhe: 1.719 ± 0.022	2.824ProGly: 2.824 ± 0.038	1.4ProHis: 1.4 ± 0.021	1.172ProIle: 1.172 ± 0.019	1.698ProLys: 1.698 ± 0.021	6.067ProLeu: 6.067 ± 0.056	0.77ProMet: 0.77 ± 0.019	1.017ProAsn: 1.017 ± 0.015	6.545ProPro: 6.545 ± 0.075	4.183ProGln: 4.183 ± 0.05	2.852ProArg: 2.852 ± 0.036	5.089ProSer: 5.089 ± 0.045	2.633ProThr: 2.633 ± 0.033	2.631ProVal: 2.631 ± 0.028	0.601ProTrp: 0.601 ± 0.012	0.87ProTyr: 0.87 ± 0.015	0.002ProXaa: 0.002 ± 0.001
Gln	3.491GlnAla: 3.491 ± 0.039	0.521GlnCys: 0.521 ± 0.011	1.626GlnAsp: 1.626 ± 0.024	5.729GlnGlu: 5.729 ± 0.067	0.794GlnPhe: 0.794 ± 0.015	3.222GlnGly: 3.222 ± 0.034	4.174GlnHis: 4.174 ± 0.062	1.174GlnIle: 1.174 ± 0.017	3.221GlnLys: 3.221 ± 0.045	9.834GlnLeu: 9.834 ± 0.124	1.208GlnMet: 1.208 ± 0.022	0.968GlnAsn: 0.968 ± 0.018	3.74GlnPro: 3.74 ± 0.057	80.151GlnGln: 80.151 ± 0.874	5.785GlnArg: 5.785 ± 0.062	1.96GlnSer: 1.96 ± 0.022	2.174GlnThr: 2.174 ± 0.025	2.09GlnVal: 2.09 ± 0.028	0.572GlnTrp: 0.572 ± 0.014	0.594GlnTyr: 0.594 ± 0.015	0.003GlnXaa: 0.003 ± 0.001
Arg	4.53ArgAla: 4.53 ± 0.035	1.275ArgCys: 1.275 ± 0.019	2.119ArgAsp: 2.119 ± 0.034	3.785ArgGlu: 3.785 ± 0.05	1.303ArgPhe: 1.303 ± 0.018	4.144ArgGly: 4.144 ± 0.047	1.384ArgHis: 1.384 ± 0.019	1.516ArgIle: 1.516 ± 0.021	2.666ArgLys: 2.666 ± 0.033	5.569ArgLeu: 5.569 ± 0.045	1.05ArgMet: 1.05 ± 0.017	1.266ArgAsn: 1.266 ± 0.019	2.534ArgPro: 2.534 ± 0.026	5.473ArgGln: 5.473 ± 0.067	6.275ArgArg: 6.275 ± 0.073	4.56ArgSer: 4.56 ± 0.051	1.906ArgThr: 1.906 ± 0.029	2.527ArgVal: 2.527 ± 0.028	0.668ArgTrp: 0.668 ± 0.013	0.796ArgTyr: 0.796 ± 0.015	0.002ArgXaa: 0.002 ± 0.001
Ser	7.186SerAla: 7.186 ± 0.055	1.923SerCys: 1.923 ± 0.023	2.32SerAsp: 2.32 ± 0.028	3.057SerGlu: 3.057 ± 0.035	2.148SerPhe: 2.148 ± 0.023	4.728SerGly: 4.728 ± 0.043	1.054SerHis: 1.054 ± 0.02	1.996SerIle: 1.996 ± 0.028	2.948SerLys: 2.948 ± 0.033	6.111SerLeu: 6.111 ± 0.049	0.916SerMet: 0.916 ± 0.014	4.059SerAsn: 4.059 ± 0.058	5.065SerPro: 5.065 ± 0.052	2.214SerGln: 2.214 ± 0.028	5.223SerArg: 5.223 ± 0.046	34.666SerSer: 34.666 ± 0.392	3.589SerThr: 3.589 ± 0.032	3.2SerVal: 3.2 ± 0.032	0.699SerTrp: 0.699 ± 0.013	0.931SerTyr: 0.931 ± 0.016	0.003SerXaa: 0.003 ± 0.001
Thr	9.167ThrAla: 9.167 ± 0.087	0.616ThrCys: 0.616 ± 0.016	1.782ThrAsp: 1.782 ± 0.029	3.29ThrGlu: 3.29 ± 0.053	0.888ThrPhe: 0.888 ± 0.015	2.919ThrGly: 2.919 ± 0.034	0.715ThrHis: 0.715 ± 0.015	1.097ThrIle: 1.097 ± 0.024	1.572ThrLys: 1.572 ± 0.03	3.028ThrLeu: 3.028 ± 0.03	0.458ThrMet: 0.458 ± 0.011	1.091ThrAsn: 1.091 ± 0.019	3.221ThrPro: 3.221 ± 0.032	1.713ThrGln: 1.713 ± 0.024	1.921ThrArg: 1.921 ± 0.027	3.023ThrSer: 3.023 ± 0.034	2.526ThrThr: 2.526 ± 0.047	2.104ThrVal: 2.104 ± 0.029	0.305ThrTrp: 0.305 ± 0.01	0.596ThrTyr: 0.596 ± 0.013	0.001ThrXaa: 0.001 ± 0.0
Val	5.334ValAla: 5.334 ± 0.05	0.988ValCys: 0.988 ± 0.016	1.804ValAsp: 1.804 ± 0.027	2.73ValGlu: 2.73 ± 0.031	1.37ValPhe: 1.37 ± 0.019	2.752ValGly: 2.752 ± 0.031	0.9ValHis: 0.9 ± 0.016	1.009ValIle: 1.009 ± 0.017	1.472ValLys: 1.472 ± 0.022	4.487ValLeu: 4.487 ± 0.041	0.613ValMet: 0.613 ± 0.015	0.838ValAsn: 0.838 ± 0.016	2.368ValPro: 2.368 ± 0.03	2.335ValGln: 2.335 ± 0.033	2.14ValArg: 2.14 ± 0.028	3.812ValSer: 3.812 ± 0.041	1.493ValThr: 1.493 ± 0.023	2.557ValVal: 2.557 ± 0.04	0.51ValTrp: 0.51 ± 0.012	1.095ValTyr: 1.095 ± 0.019	0.001ValXaa: 0.001 ± 0.0
Trp	0.702TrpAla: 0.702 ± 0.013	0.16TrpCys: 0.16 ± 0.006	0.318TrpAsp: 0.318 ± 0.009	0.539TrpGlu: 0.539 ± 0.01	0.203TrpPhe: 0.203 ± 0.008	0.982TrpGly: 0.982 ± 0.017	0.163TrpHis: 0.163 ± 0.006	0.244TrpIle: 0.244 ± 0.008	0.393TrpLys: 0.393 ± 0.01	0.987TrpLeu: 0.987 ± 0.016	0.166TrpMet: 0.166 ± 0.006	0.193TrpAsn: 0.193 ± 0.008	0.379TrpPro: 0.379 ± 0.009	0.578TrpGln: 0.578 ± 0.016	0.841TrpArg: 0.841 ± 0.017	0.539TrpSer: 0.539 ± 0.011	0.353TrpThr: 0.353 ± 0.008	0.431TrpVal: 0.431 ± 0.01	0.153TrpTrp: 0.153 ± 0.006	0.1TrpTyr: 0.1 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.039TyrAla: 1.039 ± 0.017	0.328TyrCys: 0.328 ± 0.015	0.537TyrAsp: 0.537 ± 0.013	0.751TyrGlu: 0.751 ± 0.015	0.506TyrPhe: 0.506 ± 0.013	0.895TyrGly: 0.895 ± 0.017	0.278TyrHis: 0.278 ± 0.009	0.51TyrIle: 0.51 ± 0.013	0.561TyrLys: 0.561 ± 0.011	1.326TyrLeu: 1.326 ± 0.018	0.26TyrMet: 0.26 ± 0.008	0.367TyrAsn: 0.367 ± 0.01	0.742TyrPro: 0.742 ± 0.017	0.545TyrGln: 0.545 ± 0.013	1.034TyrArg: 1.034 ± 0.015	1.124TyrSer: 1.124 ± 0.017	0.808TyrThr: 0.808 ± 0.013	0.701TyrVal: 0.701 ± 0.014	0.175TyrTrp: 0.175 ± 0.007	0.341TyrTyr: 0.341 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.001	0.005XaaGln: 0.005 ± 0.001	0.002XaaArg: 0.002 ± 0.001	0.003XaaSer: 0.003 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.246XaaXaa: 0.246 ± 0.049

Statistics based on 8711 proteins (4764477 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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