Human papillomavirus type 34

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 11

Average proteome isoelectric point is 6.52

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0P0E4T0|A0A0P0E4T0_HPV34 Regulatory protein E2 OS=Human papillomavirus type 34 OX=333764 GN=E2 PE=3 SV=1
MM1 pKa = 7.42HH2 pKa = 7.26GKK4 pKa = 9.75KK5 pKa = 10.09PSVQDD10 pKa = 2.98IVLDD14 pKa = 4.08LKK16 pKa = 10.25PTTEE20 pKa = 4.22TDD22 pKa = 3.49LTCYY26 pKa = 10.43EE27 pKa = 4.38SLDD30 pKa = 3.63NSEE33 pKa = 5.89DD34 pKa = 3.66EE35 pKa = 5.64DD36 pKa = 3.89EE37 pKa = 4.61TDD39 pKa = 3.38SHH41 pKa = 7.87LEE43 pKa = 4.01RR44 pKa = 11.84QAEE47 pKa = 4.18QAWYY51 pKa = 10.13RR52 pKa = 11.84IVTDD56 pKa = 3.88CSRR59 pKa = 11.84CEE61 pKa = 3.94STVCLTIEE69 pKa = 4.18STHH72 pKa = 6.69ADD74 pKa = 3.8LLVLEE79 pKa = 5.03DD80 pKa = 4.85LLMGALKK87 pKa = 9.96IVCPNCSRR95 pKa = 11.84RR96 pKa = 11.84LL97 pKa = 3.52

Molecular weight: 10.99 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0P0F0M0|A0A0P0F0M0_HPV34 Replication protein E1 OS=Human papillomavirus type 34 OX=333764 GN=E1 PE=3 SV=1
MM1 pKa = 7.78IIFIFVILFVFGFYY15 pKa = 9.48MCLSVSLAVSVCVYY29 pKa = 11.03AWLLLLIIITFLHH42 pKa = 6.42VSQSLLKK49 pKa = 10.51VYY51 pKa = 10.33ILYY54 pKa = 10.53VCVFYY59 pKa = 10.81IPMALVHH66 pKa = 5.85YY67 pKa = 9.49HH68 pKa = 6.33ATLQVTT74 pKa = 4.2

Molecular weight: 8.57 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2285

74

647

326.4

36.73

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.295 ± 0.498

2.976 ± 0.64

5.777 ± 0.4

4.77 ± 0.473

3.807 ± 0.342

5.602 ± 0.607

2.495 ± 0.417

5.339 ± 0.453

5.252 ± 0.627

8.359 ± 0.6

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.057 ± 0.43

4.683 ± 0.403

5.952 ± 1.042

4.639 ± 0.414

4.726 ± 0.448

7.965 ± 0.411

7.834 ± 0.989

6.783 ± 0.635

1.575 ± 0.387

4.114 ± 0.366
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski