Amino acid dipepetide frequency for Cadicivirus A (isolate Dog/Hong Kong/209/2008)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.446AlaAla: 4.446 ± 0.5
0.445AlaCys: 0.445 ± 0.25
4.891AlaAsp: 4.891 ± 0.084
2.668AlaGlu: 2.668 ± 0.167
4.446AlaPhe: 4.446 ± 0.832
4.891AlaGly: 4.891 ± 1.248
1.779AlaHis: 1.779 ± 0.333
3.557AlaIle: 3.557 ± 0.0
3.557AlaLys: 3.557 ± 0.0
6.67AlaLeu: 6.67 ± 0.915
1.779AlaMet: 1.779 ± 0.333
3.112AlaAsn: 3.112 ± 0.915
4.446AlaPro: 4.446 ± 1.497
0.445AlaGln: 0.445 ± 0.416
3.112AlaArg: 3.112 ± 0.249
6.67AlaSer: 6.67 ± 0.249
4.446AlaThr: 4.446 ± 0.832
6.67AlaVal: 6.67 ± 0.417
0.0AlaTrp: 0.0 ± 0.0
2.668AlaTyr: 2.668 ± 0.832
0.0AlaXaa: 0.0 ± 0.0
Cys
0.889CysAla: 0.889 ± 0.166
0.445CysCys: 0.445 ± 0.416
0.445CysAsp: 0.445 ± 0.25
2.668CysGlu: 2.668 ± 0.832
1.334CysPhe: 1.334 ± 0.749
0.889CysGly: 0.889 ± 0.499
0.445CysHis: 0.445 ± 0.25
0.445CysIle: 0.445 ± 0.416
1.334CysLys: 1.334 ± 0.749
0.889CysLeu: 0.889 ± 0.166
0.445CysMet: 0.445 ± 0.416
0.889CysAsn: 0.889 ± 0.499
0.0CysPro: 0.0 ± 0.0
0.889CysGln: 0.889 ± 0.166
0.0CysArg: 0.0 ± 0.0
1.779CysSer: 1.779 ± 0.333
0.889CysThr: 0.889 ± 0.166
0.889CysVal: 0.889 ± 0.499
0.445CysTrp: 0.445 ± 0.25
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.557AspAla: 3.557 ± 0.665
0.445AspCys: 0.445 ± 0.25
4.446AspAsp: 4.446 ± 1.831
3.112AspGlu: 3.112 ± 1.748
1.779AspPhe: 1.779 ± 0.333
3.557AspGly: 3.557 ± 1.332
0.889AspHis: 0.889 ± 0.166
4.002AspIle: 4.002 ± 2.247
4.002AspLys: 4.002 ± 2.247
4.891AspLeu: 4.891 ± 0.749
1.779AspMet: 1.779 ± 0.998
1.779AspAsn: 1.779 ± 0.333
4.446AspPro: 4.446 ± 0.5
0.0AspGln: 0.0 ± 0.0
2.668AspArg: 2.668 ± 0.167
4.446AspSer: 4.446 ± 0.166
4.446AspThr: 4.446 ± 0.5
6.225AspVal: 6.225 ± 0.833
1.779AspTrp: 1.779 ± 0.999
3.112AspTyr: 3.112 ± 0.416
0.0AspXaa: 0.0 ± 0.0
Glu
3.557GluAla: 3.557 ± 1.332
1.334GluCys: 1.334 ± 0.749
4.002GluAsp: 4.002 ± 1.581
1.779GluGlu: 1.779 ± 0.999
4.002GluPhe: 4.002 ± 0.416
2.223GluGly: 2.223 ± 1.248
0.445GluHis: 0.445 ± 0.25
3.557GluIle: 3.557 ± 0.0
3.112GluLys: 3.112 ± 1.748
6.225GluLeu: 6.225 ± 1.498
2.223GluMet: 2.223 ± 0.808
1.334GluAsn: 1.334 ± 0.749
3.557GluPro: 3.557 ± 0.666
0.0GluGln: 0.0 ± 0.0
1.779GluArg: 1.779 ± 0.999
4.446GluSer: 4.446 ± 1.165
2.668GluThr: 2.668 ± 0.832
4.446GluVal: 4.446 ± 0.166
0.889GluTrp: 0.889 ± 0.166
2.223GluTyr: 2.223 ± 0.583
0.0GluXaa: 0.0 ± 0.0
Phe
5.336PheAla: 5.336 ± 1.665
1.779PheCys: 1.779 ± 0.333
4.446PheAsp: 4.446 ± 0.832
5.336PheGlu: 5.336 ± 0.333
0.889PhePhe: 0.889 ± 0.832
4.002PheGly: 4.002 ± 0.416
1.334PheHis: 1.334 ± 0.582
4.002PheIle: 4.002 ± 0.25
1.334PheLys: 1.334 ± 0.749
2.668PheLeu: 2.668 ± 0.167
0.889PheMet: 0.889 ± 0.499
2.668PheAsn: 2.668 ± 0.832
4.002PhePro: 4.002 ± 1.081
1.334PheGln: 1.334 ± 1.248
0.889PheArg: 0.889 ± 0.166
7.114PheSer: 7.114 ± 0.666
2.668PheThr: 2.668 ± 1.165
3.557PheVal: 3.557 ± 0.665
0.445PheTrp: 0.445 ± 0.25
0.445PheTyr: 0.445 ± 0.25
0.0PheXaa: 0.0 ± 0.0
Gly
2.668GlyAla: 2.668 ± 0.499
2.668GlyCys: 2.668 ± 0.167
1.334GlyAsp: 1.334 ± 0.749
4.446GlyGlu: 4.446 ± 0.166
5.336GlyPhe: 5.336 ± 0.998
0.889GlyGly: 0.889 ± 0.166
0.889GlyHis: 0.889 ± 0.166
0.889GlyIle: 0.889 ± 0.499
4.002GlyLys: 4.002 ± 1.581
7.559GlyLeu: 7.559 ± 1.081
1.334GlyMet: 1.334 ± 0.749
3.557GlyAsn: 3.557 ± 1.331
4.002GlyPro: 4.002 ± 1.747
0.889GlyGln: 0.889 ± 0.166
2.223GlyArg: 2.223 ± 0.749
3.112GlySer: 3.112 ± 0.915
3.557GlyThr: 3.557 ± 1.331
4.891GlyVal: 4.891 ± 0.582
0.445GlyTrp: 0.445 ± 0.416
1.334GlyTyr: 1.334 ± 0.749
0.445GlyXaa: 0.445 ± 0.416
His
1.334HisAla: 1.334 ± 0.083
0.0HisCys: 0.0 ± 0.0
2.668HisAsp: 2.668 ± 0.832
0.889HisGlu: 0.889 ± 0.499
0.0HisPhe: 0.0 ± 0.0
2.223HisGly: 2.223 ± 0.749
0.445HisHis: 0.445 ± 0.25
0.0HisIle: 0.0 ± 0.0
0.445HisLys: 0.445 ± 0.25
1.334HisLeu: 1.334 ± 0.749
0.889HisMet: 0.889 ± 0.499
0.889HisAsn: 0.889 ± 0.832
1.779HisPro: 1.779 ± 0.333
0.445HisGln: 0.445 ± 0.416
0.445HisArg: 0.445 ± 0.25
0.0HisSer: 0.0 ± 0.0
1.779HisThr: 1.779 ± 0.333
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.889HisTyr: 0.889 ± 0.166
0.0HisXaa: 0.0 ± 0.0
Ile
3.112IleAla: 3.112 ± 1.748
0.889IleCys: 0.889 ± 0.499
4.446IleAsp: 4.446 ± 0.5
3.112IleGlu: 3.112 ± 1.082
2.668IlePhe: 2.668 ± 0.167
3.112IleGly: 3.112 ± 0.915
1.779IleHis: 1.779 ± 0.999
1.334IleIle: 1.334 ± 0.749
4.891IleLys: 4.891 ± 2.081
2.668IleLeu: 2.668 ± 0.832
0.889IleMet: 0.889 ± 0.166
4.002IleAsn: 4.002 ± 1.747
7.114IlePro: 7.114 ± 1.331
0.445IleGln: 0.445 ± 0.416
0.445IleArg: 0.445 ± 0.25
6.225IleSer: 6.225 ± 1.164
2.223IleThr: 2.223 ± 0.583
2.223IleVal: 2.223 ± 0.083
0.0IleTrp: 0.0 ± 0.0
3.112IleTyr: 3.112 ± 0.249
0.0IleXaa: 0.0 ± 0.0
Lys
4.891LysAla: 4.891 ± 2.081
0.445LysCys: 0.445 ± 0.416
5.78LysAsp: 5.78 ± 2.58
3.112LysGlu: 3.112 ± 1.748
3.112LysPhe: 3.112 ± 0.416
2.668LysGly: 2.668 ± 0.167
1.779LysHis: 1.779 ± 0.999
2.668LysIle: 2.668 ± 1.498
6.225LysLys: 6.225 ± 3.496
5.336LysLeu: 5.336 ± 2.33
3.112LysMet: 3.112 ± 1.216
2.668LysAsn: 2.668 ± 0.832
3.112LysPro: 3.112 ± 0.416
0.445LysGln: 0.445 ± 0.25
1.779LysArg: 1.779 ± 0.999
2.223LysSer: 2.223 ± 1.248
3.557LysThr: 3.557 ± 0.0
8.448LysVal: 8.448 ± 2.747
0.889LysTrp: 0.889 ± 0.499
2.668LysTyr: 2.668 ± 1.498
0.0LysXaa: 0.0 ± 0.0
Leu
5.336LeuAla: 5.336 ± 0.332
2.223LeuCys: 2.223 ± 1.248
4.891LeuAsp: 4.891 ± 0.084
5.78LeuGlu: 5.78 ± 3.246
2.668LeuPhe: 2.668 ± 1.498
4.891LeuGly: 4.891 ± 1.248
0.889LeuHis: 0.889 ± 0.499
4.891LeuIle: 4.891 ± 1.415
7.114LeuLys: 7.114 ± 2.663
6.225LeuLeu: 6.225 ± 1.164
0.889LeuMet: 0.889 ± 0.832
3.557LeuAsn: 3.557 ± 0.0
7.114LeuPro: 7.114 ± 2.662
0.889LeuGln: 0.889 ± 0.832
4.891LeuArg: 4.891 ± 0.582
7.559LeuSer: 7.559 ± 1.747
4.446LeuThr: 4.446 ± 0.5
3.557LeuVal: 3.557 ± 0.665
0.445LeuTrp: 0.445 ± 0.25
6.225LeuTyr: 6.225 ± 0.499
0.0LeuXaa: 0.0 ± 0.0
Met
3.112MetAla: 3.112 ± 0.416
0.445MetCys: 0.445 ± 0.416
1.334MetAsp: 1.334 ± 0.083
1.334MetGlu: 1.334 ± 0.749
1.334MetPhe: 1.334 ± 0.749
0.889MetGly: 0.889 ± 0.166
0.445MetHis: 0.445 ± 0.25
1.334MetIle: 1.334 ± 0.083
1.779MetLys: 1.779 ± 0.999
2.668MetLeu: 2.668 ± 0.499
0.0MetMet: 0.0 ± 0.0
1.334MetAsn: 1.334 ± 0.582
1.334MetPro: 1.334 ± 0.083
0.0MetGln: 0.0 ± 0.0
0.445MetArg: 0.445 ± 0.25
1.334MetSer: 1.334 ± 0.582
2.223MetThr: 2.223 ± 0.083
0.445MetVal: 0.445 ± 0.25
0.445MetTrp: 0.445 ± 0.25
1.779MetTyr: 1.779 ± 0.333
0.0MetXaa: 0.0 ± 0.0
Asn
2.668AsnAla: 2.668 ± 0.499
0.445AsnCys: 0.445 ± 0.25
1.334AsnAsp: 1.334 ± 0.749
1.779AsnGlu: 1.779 ± 0.333
2.668AsnPhe: 2.668 ± 0.167
4.002AsnGly: 4.002 ± 0.916
0.445AsnHis: 0.445 ± 0.416
4.446AsnIle: 4.446 ± 0.166
3.112AsnLys: 3.112 ± 1.082
4.002AsnLeu: 4.002 ± 1.581
0.889AsnMet: 0.889 ± 0.166
2.668AsnAsn: 2.668 ± 1.165
2.223AsnPro: 2.223 ± 0.749
1.779AsnGln: 1.779 ± 1.664
1.334AsnArg: 1.334 ± 0.083
3.112AsnSer: 3.112 ± 0.915
5.78AsnThr: 5.78 ± 0.083
1.779AsnVal: 1.779 ± 0.333
1.779AsnTrp: 1.779 ± 0.333
0.445AsnTyr: 0.445 ± 0.416
0.0AsnXaa: 0.0 ± 0.0
Pro
3.557ProAla: 3.557 ± 0.665
0.445ProCys: 0.445 ± 0.25
2.668ProAsp: 2.668 ± 0.832
3.557ProGlu: 3.557 ± 1.332
5.336ProPhe: 5.336 ± 2.33
4.446ProGly: 4.446 ± 1.497
0.889ProHis: 0.889 ± 0.832
5.78ProIle: 5.78 ± 2.746
4.002ProLys: 4.002 ± 0.916
4.002ProLeu: 4.002 ± 0.416
0.889ProMet: 0.889 ± 0.166
2.668ProAsn: 2.668 ± 0.167
2.223ProPro: 2.223 ± 0.083
0.0ProGln: 0.0 ± 0.0
1.334ProArg: 1.334 ± 0.083
6.67ProSer: 6.67 ± 1.581
8.893ProThr: 8.893 ± 4.992
5.336ProVal: 5.336 ± 0.333
0.0ProTrp: 0.0 ± 0.0
2.668ProTyr: 2.668 ± 0.832
0.0ProXaa: 0.0 ± 0.0
Gln
2.223GlnAla: 2.223 ± 1.414
0.0GlnCys: 0.0 ± 0.0
0.445GlnAsp: 0.445 ± 0.25
0.445GlnGlu: 0.445 ± 0.416
1.334GlnPhe: 1.334 ± 1.248
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
0.445GlnLeu: 0.445 ± 0.416
0.889GlnMet: 0.889 ± 0.166
0.0GlnAsn: 0.0 ± 0.0
1.779GlnPro: 1.779 ± 1.664
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
1.334GlnSer: 1.334 ± 1.248
0.889GlnThr: 0.889 ± 0.832
0.445GlnVal: 0.445 ± 0.416
0.445GlnTrp: 0.445 ± 0.416
0.445GlnTyr: 0.445 ± 0.416
0.0GlnXaa: 0.0 ± 0.0
Arg
0.889ArgAla: 0.889 ± 0.166
0.445ArgCys: 0.445 ± 0.25
1.779ArgAsp: 1.779 ± 0.333
0.445ArgGlu: 0.445 ± 0.25
4.002ArgPhe: 4.002 ± 0.416
1.779ArgGly: 1.779 ± 0.333
0.889ArgHis: 0.889 ± 0.166
1.334ArgIle: 1.334 ± 0.083
4.002ArgLys: 4.002 ± 1.581
3.557ArgLeu: 3.557 ± 1.331
0.889ArgMet: 0.889 ± 0.166
2.223ArgAsn: 2.223 ± 1.248
1.779ArgPro: 1.779 ± 0.998
0.0ArgGln: 0.0 ± 0.0
1.779ArgArg: 1.779 ± 0.999
2.668ArgSer: 2.668 ± 1.165
4.002ArgThr: 4.002 ± 0.25
2.668ArgVal: 2.668 ± 0.167
0.445ArgTrp: 0.445 ± 0.25
1.334ArgTyr: 1.334 ± 0.749
0.0ArgXaa: 0.0 ± 0.0
Ser
7.114SerAla: 7.114 ± 2.662
1.334SerCys: 1.334 ± 0.083
5.78SerAsp: 5.78 ± 0.083
4.446SerGlu: 4.446 ± 1.831
5.336SerPhe: 5.336 ± 0.333
4.446SerGly: 4.446 ± 2.829
0.0SerHis: 0.0 ± 0.0
3.557SerIle: 3.557 ± 0.665
3.557SerLys: 3.557 ± 0.666
8.004SerLeu: 8.004 ± 0.831
2.223SerMet: 2.223 ± 0.749
4.446SerAsn: 4.446 ± 0.166
5.336SerPro: 5.336 ± 0.332
2.668SerGln: 2.668 ± 2.496
3.557SerArg: 3.557 ± 0.0
5.336SerSer: 5.336 ± 2.33
4.446SerThr: 4.446 ± 1.497
6.225SerVal: 6.225 ± 1.164
0.445SerTrp: 0.445 ± 0.416
3.112SerTyr: 3.112 ± 0.249
0.0SerXaa: 0.0 ± 0.0
Thr
6.67ThrAla: 6.67 ± 0.915
0.445ThrCys: 0.445 ± 0.416
4.002ThrAsp: 4.002 ± 0.25
3.557ThrGlu: 3.557 ± 0.665
3.112ThrPhe: 3.112 ± 0.249
5.336ThrGly: 5.336 ± 1.664
1.334ThrHis: 1.334 ± 0.749
2.223ThrIle: 2.223 ± 0.083
5.336ThrLys: 5.336 ± 1.665
8.893ThrLeu: 8.893 ± 1.664
0.445ThrMet: 0.445 ± 0.25
4.002ThrAsn: 4.002 ± 1.747
4.891ThrPro: 4.891 ± 0.749
0.445ThrGln: 0.445 ± 0.416
4.446ThrArg: 4.446 ± 0.832
6.225ThrSer: 6.225 ± 2.496
8.448ThrThr: 8.448 ± 3.91
4.446ThrVal: 4.446 ± 2.163
0.445ThrTrp: 0.445 ± 0.25
3.112ThrTyr: 3.112 ± 1.581
0.0ThrXaa: 0.0 ± 0.0
Val
5.78ValAla: 5.78 ± 2.746
0.889ValCys: 0.889 ± 0.499
4.002ValAsp: 4.002 ± 0.916
3.557ValGlu: 3.557 ± 0.666
2.668ValPhe: 2.668 ± 1.498
3.557ValGly: 3.557 ± 0.665
0.889ValHis: 0.889 ± 0.166
6.67ValIle: 6.67 ± 1.748
4.446ValLys: 4.446 ± 1.831
2.223ValLeu: 2.223 ± 0.583
0.889ValMet: 0.889 ± 0.166
1.779ValAsn: 1.779 ± 0.333
3.557ValPro: 3.557 ± 0.665
0.445ValGln: 0.445 ± 0.416
3.557ValArg: 3.557 ± 0.0
8.448ValSer: 8.448 ± 1.248
6.67ValThr: 6.67 ± 1.581
5.336ValVal: 5.336 ± 0.998
1.334ValTrp: 1.334 ± 1.248
3.557ValTyr: 3.557 ± 0.665
0.0ValXaa: 0.0 ± 0.0
Trp
0.889TrpAla: 0.889 ± 0.832
0.889TrpCys: 0.889 ± 0.499
0.445TrpAsp: 0.445 ± 0.25
0.0TrpGlu: 0.0 ± 0.0
0.445TrpPhe: 0.445 ± 0.416
0.445TrpGly: 0.445 ± 0.416
0.0TrpHis: 0.0 ± 0.0
1.334TrpIle: 1.334 ± 0.083
0.445TrpLys: 0.445 ± 0.25
1.334TrpLeu: 1.334 ± 0.083
1.334TrpMet: 1.334 ± 0.749
0.445TrpAsn: 0.445 ± 0.25
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.889TrpArg: 0.889 ± 0.166
0.889TrpSer: 0.889 ± 0.832
0.445TrpThr: 0.445 ± 0.25
0.445TrpVal: 0.445 ± 0.416
0.0TrpTrp: 0.0 ± 0.0
0.445TrpTyr: 0.445 ± 0.25
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.223TyrAla: 2.223 ± 0.749
0.0TyrCys: 0.0 ± 0.0
2.223TyrAsp: 2.223 ± 0.583
1.779TyrGlu: 1.779 ± 0.333
2.668TyrPhe: 2.668 ± 0.832
2.223TyrGly: 2.223 ± 1.248
0.889TyrHis: 0.889 ± 0.499
2.668TyrIle: 2.668 ± 1.165
2.668TyrLys: 2.668 ± 0.167
4.891TyrLeu: 4.891 ± 0.749
0.889TyrMet: 0.889 ± 0.499
2.668TyrAsn: 2.668 ± 1.498
2.668TyrPro: 2.668 ± 0.499
0.0TyrGln: 0.0 ± 0.0
1.334TyrArg: 1.334 ± 0.749
1.779TyrSer: 1.779 ± 0.333
5.336TyrThr: 5.336 ± 1.664
2.223TyrVal: 2.223 ± 0.749
0.445TyrTrp: 0.445 ± 0.416
1.334TyrTyr: 1.334 ± 0.083
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.445XaaAla: 0.445 ± 0.416
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2250 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski