Amino acid dipepetide frequency for Talpa europaea papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.975AlaAla: 3.975 ± 1.156
0.442AlaCys: 0.442 ± 0.41
3.534AlaAsp: 3.534 ± 0.982
4.417AlaGlu: 4.417 ± 1.508
4.859AlaPhe: 4.859 ± 0.78
0.442AlaGly: 0.442 ± 0.386
0.0AlaHis: 0.0 ± 0.0
2.208AlaIle: 2.208 ± 0.411
2.65AlaLys: 2.65 ± 0.913
4.417AlaLeu: 4.417 ± 1.429
3.092AlaMet: 3.092 ± 1.271
1.325AlaAsn: 1.325 ± 0.718
2.208AlaPro: 2.208 ± 1.246
2.208AlaGln: 2.208 ± 0.938
2.65AlaArg: 2.65 ± 1.213
3.975AlaSer: 3.975 ± 1.695
1.767AlaThr: 1.767 ± 0.576
2.208AlaVal: 2.208 ± 0.772
0.0AlaTrp: 0.0 ± 0.0
2.65AlaTyr: 2.65 ± 1.33
0.0AlaXaa: 0.0 ± 0.0
Cys
0.442CysAla: 0.442 ± 0.335
0.883CysCys: 0.883 ± 0.893
0.0CysAsp: 0.0 ± 0.0
0.883CysGlu: 0.883 ± 0.43
0.0CysPhe: 0.0 ± 0.0
1.325CysGly: 1.325 ± 1.224
0.0CysHis: 0.0 ± 0.0
0.442CysIle: 0.442 ± 0.547
4.417CysLys: 4.417 ± 1.416
2.208CysLeu: 2.208 ± 1.281
0.442CysMet: 0.442 ± 0.335
1.325CysAsn: 1.325 ± 0.688
1.325CysPro: 1.325 ± 0.762
0.0CysGln: 0.0 ± 0.0
0.883CysArg: 0.883 ± 0.612
2.208CysSer: 2.208 ± 1.375
0.442CysThr: 0.442 ± 0.479
0.883CysVal: 0.883 ± 0.473
0.442CysTrp: 0.442 ± 0.335
1.325CysTyr: 1.325 ± 1.151
0.0CysXaa: 0.0 ± 0.0
Asp
1.325AspAla: 1.325 ± 0.667
0.883AspCys: 0.883 ± 0.67
3.975AspAsp: 3.975 ± 1.823
6.184AspGlu: 6.184 ± 1.507
2.208AspPhe: 2.208 ± 1.219
3.534AspGly: 3.534 ± 1.447
0.883AspHis: 0.883 ± 0.43
5.742AspIle: 5.742 ± 1.623
2.208AspLys: 2.208 ± 0.745
3.975AspLeu: 3.975 ± 1.077
0.883AspMet: 0.883 ± 0.473
2.65AspAsn: 2.65 ± 0.97
3.975AspPro: 3.975 ± 1.226
2.208AspGln: 2.208 ± 0.71
1.767AspArg: 1.767 ± 1.032
4.859AspSer: 4.859 ± 1.746
1.325AspThr: 1.325 ± 0.554
4.417AspVal: 4.417 ± 0.651
0.883AspTrp: 0.883 ± 0.612
1.767AspTyr: 1.767 ± 0.576
0.0AspXaa: 0.0 ± 0.0
Glu
3.092GluAla: 3.092 ± 1.358
0.883GluCys: 0.883 ± 0.67
4.859GluAsp: 4.859 ± 2.036
7.951GluGlu: 7.951 ± 2.822
1.767GluPhe: 1.767 ± 0.576
5.3GluGly: 5.3 ± 1.157
0.883GluHis: 0.883 ± 0.697
5.3GluIle: 5.3 ± 1.816
2.65GluLys: 2.65 ± 1.488
8.392GluLeu: 8.392 ± 2.145
0.883GluMet: 0.883 ± 0.861
4.417GluAsn: 4.417 ± 1.392
3.534GluPro: 3.534 ± 1.233
4.859GluGln: 4.859 ± 1.261
2.208GluArg: 2.208 ± 0.954
5.3GluSer: 5.3 ± 1.753
5.742GluThr: 5.742 ± 1.418
1.325GluVal: 1.325 ± 0.989
1.767GluTrp: 1.767 ± 1.003
1.325GluTyr: 1.325 ± 0.799
0.0GluXaa: 0.0 ± 0.0
Phe
2.208PheAla: 2.208 ± 0.938
1.767PheCys: 1.767 ± 1.016
4.417PheAsp: 4.417 ± 0.925
5.742PheGlu: 5.742 ± 1.444
3.092PhePhe: 3.092 ± 0.805
1.767PheGly: 1.767 ± 0.63
0.883PheHis: 0.883 ± 0.663
3.534PheIle: 3.534 ± 1.412
1.767PheLys: 1.767 ± 0.604
2.65PheLeu: 2.65 ± 1.603
0.442PheMet: 0.442 ± 0.406
1.767PheAsn: 1.767 ± 0.946
1.767PhePro: 1.767 ± 1.158
1.767PheGln: 1.767 ± 0.63
1.767PheArg: 1.767 ± 0.613
3.975PheSer: 3.975 ± 1.583
2.65PheThr: 2.65 ± 0.972
2.65PheVal: 2.65 ± 0.769
2.208PheTrp: 2.208 ± 0.878
1.325PheTyr: 1.325 ± 0.408
0.0PheXaa: 0.0 ± 0.0
Gly
1.325GlyAla: 1.325 ± 0.427
0.883GlyCys: 0.883 ± 0.697
3.534GlyAsp: 3.534 ± 1.666
3.975GlyGlu: 3.975 ± 1.271
1.325GlyPhe: 1.325 ± 0.467
3.975GlyGly: 3.975 ± 1.272
0.883GlyHis: 0.883 ± 0.475
2.208GlyIle: 2.208 ± 0.818
2.208GlyLys: 2.208 ± 1.18
3.534GlyLeu: 3.534 ± 0.947
0.883GlyMet: 0.883 ± 0.473
3.534GlyAsn: 3.534 ± 1.924
6.184GlyPro: 6.184 ± 2.35
1.325GlyGln: 1.325 ± 0.68
5.3GlyArg: 5.3 ± 2.074
6.625GlySer: 6.625 ± 1.648
4.859GlyThr: 4.859 ± 1.553
5.3GlyVal: 5.3 ± 1.73
0.442GlyTrp: 0.442 ± 0.479
0.883GlyTyr: 0.883 ± 0.475
0.0GlyXaa: 0.0 ± 0.0
His
0.442HisAla: 0.442 ± 0.386
0.442HisCys: 0.442 ± 0.335
0.442HisAsp: 0.442 ± 0.479
0.883HisGlu: 0.883 ± 0.727
1.325HisPhe: 1.325 ± 1.23
0.883HisGly: 0.883 ± 0.43
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.325HisLys: 1.325 ± 0.427
2.208HisLeu: 2.208 ± 0.81
0.442HisMet: 0.442 ± 0.386
0.0HisAsn: 0.0 ± 0.0
0.883HisPro: 0.883 ± 0.475
0.883HisGln: 0.883 ± 0.43
0.883HisArg: 0.883 ± 0.514
1.767HisSer: 1.767 ± 1.027
2.208HisThr: 2.208 ± 0.922
2.65HisVal: 2.65 ± 0.592
1.325HisTrp: 1.325 ± 0.87
0.883HisTyr: 0.883 ± 0.561
0.0HisXaa: 0.0 ± 0.0
Ile
1.325IleAla: 1.325 ± 0.771
0.442IleCys: 0.442 ± 0.386
3.534IleAsp: 3.534 ± 1.058
4.859IleGlu: 4.859 ± 1.593
2.208IlePhe: 2.208 ± 0.878
3.534IleGly: 3.534 ± 1.288
1.325IleHis: 1.325 ± 0.408
2.208IleIle: 2.208 ± 1.21
3.534IleLys: 3.534 ± 1.517
2.65IleLeu: 2.65 ± 1.13
0.442IleMet: 0.442 ± 0.386
3.534IleAsn: 3.534 ± 1.449
3.092IlePro: 3.092 ± 1.482
1.325IleGln: 1.325 ± 0.653
3.534IleArg: 3.534 ± 1.192
2.65IleSer: 2.65 ± 0.802
3.092IleThr: 3.092 ± 1.077
3.975IleVal: 3.975 ± 1.104
0.0IleTrp: 0.0 ± 0.0
2.65IleTyr: 2.65 ± 1.009
0.0IleXaa: 0.0 ± 0.0
Lys
3.534LysAla: 3.534 ± 1.294
1.325LysCys: 1.325 ± 0.87
2.208LysAsp: 2.208 ± 0.89
4.417LysGlu: 4.417 ± 1.629
3.092LysPhe: 3.092 ± 1.179
3.092LysGly: 3.092 ± 1.785
1.767LysHis: 1.767 ± 0.604
2.208LysIle: 2.208 ± 0.82
3.975LysLys: 3.975 ± 1.549
3.092LysLeu: 3.092 ± 1.428
1.325LysMet: 1.325 ± 0.667
1.767LysAsn: 1.767 ± 0.886
1.325LysPro: 1.325 ± 0.72
2.208LysGln: 2.208 ± 0.759
5.3LysArg: 5.3 ± 1.213
3.534LysSer: 3.534 ± 2.26
2.65LysThr: 2.65 ± 0.842
3.534LysVal: 3.534 ± 1.154
0.442LysTrp: 0.442 ± 0.386
1.325LysTyr: 1.325 ± 0.467
0.0LysXaa: 0.0 ± 0.0
Leu
4.859LeuAla: 4.859 ± 1.364
3.092LeuCys: 3.092 ± 1.589
5.742LeuAsp: 5.742 ± 1.352
3.534LeuGlu: 3.534 ± 1.682
4.859LeuPhe: 4.859 ± 1.601
7.509LeuGly: 7.509 ± 2.671
3.534LeuHis: 3.534 ± 1.56
3.092LeuIle: 3.092 ± 0.888
6.184LeuLys: 6.184 ± 1.85
9.276LeuLeu: 9.276 ± 2.165
1.767LeuMet: 1.767 ± 0.826
3.092LeuAsn: 3.092 ± 0.782
4.859LeuPro: 4.859 ± 1.507
5.742LeuGln: 5.742 ± 1.273
3.975LeuArg: 3.975 ± 1.142
6.184LeuSer: 6.184 ± 1.657
5.3LeuThr: 5.3 ± 0.811
6.625LeuVal: 6.625 ± 1.202
0.883LeuTrp: 0.883 ± 0.697
3.534LeuTyr: 3.534 ± 1.161
0.0LeuXaa: 0.0 ± 0.0
Met
2.208MetAla: 2.208 ± 1.064
0.0MetCys: 0.0 ± 0.0
1.325MetAsp: 1.325 ± 0.762
1.325MetGlu: 1.325 ± 1.079
1.325MetPhe: 1.325 ± 0.745
0.442MetGly: 0.442 ± 0.335
0.0MetHis: 0.0 ± 0.0
2.65MetIle: 2.65 ± 0.938
0.0MetLys: 0.0 ± 0.0
1.325MetLeu: 1.325 ± 0.723
0.0MetMet: 0.0 ± 0.0
1.325MetAsn: 1.325 ± 1.157
0.442MetPro: 0.442 ± 0.335
1.767MetGln: 1.767 ± 1.027
0.0MetArg: 0.0 ± 0.0
2.65MetSer: 2.65 ± 1.289
1.325MetThr: 1.325 ± 0.813
1.325MetVal: 1.325 ± 0.427
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.767AsnAla: 1.767 ± 0.576
1.767AsnCys: 1.767 ± 0.844
3.092AsnAsp: 3.092 ± 1.502
1.325AsnGlu: 1.325 ± 0.935
3.534AsnPhe: 3.534 ± 1.155
2.208AsnGly: 2.208 ± 0.454
0.0AsnHis: 0.0 ± 0.0
1.767AsnIle: 1.767 ± 0.776
2.208AsnLys: 2.208 ± 0.685
3.975AsnLeu: 3.975 ± 1.271
0.442AsnMet: 0.442 ± 0.386
2.208AsnAsn: 2.208 ± 0.954
2.65AsnPro: 2.65 ± 1.111
2.208AsnGln: 2.208 ± 0.954
3.534AsnArg: 3.534 ± 1.121
4.417AsnSer: 4.417 ± 0.823
4.417AsnThr: 4.417 ± 1.528
1.325AsnVal: 1.325 ± 0.427
0.883AsnTrp: 0.883 ± 0.67
0.883AsnTyr: 0.883 ± 0.771
0.0AsnXaa: 0.0 ± 0.0
Pro
5.3ProAla: 5.3 ± 1.439
0.883ProCys: 0.883 ± 0.612
2.65ProAsp: 2.65 ± 1.268
3.534ProGlu: 3.534 ± 0.996
1.325ProPhe: 1.325 ± 0.505
1.325ProGly: 1.325 ± 0.904
0.883ProHis: 0.883 ± 0.561
2.65ProIle: 2.65 ± 1.724
2.208ProLys: 2.208 ± 0.759
7.067ProLeu: 7.067 ± 1.158
0.442ProMet: 0.442 ± 0.335
3.092ProAsn: 3.092 ± 1.752
6.184ProPro: 6.184 ± 1.123
0.883ProGln: 0.883 ± 0.475
5.3ProArg: 5.3 ± 1.739
5.3ProSer: 5.3 ± 2.2
3.534ProThr: 3.534 ± 1.972
3.975ProVal: 3.975 ± 1.683
0.442ProTrp: 0.442 ± 0.547
2.208ProTyr: 2.208 ± 1.247
0.0ProXaa: 0.0 ± 0.0
Gln
0.883GlnAla: 0.883 ± 0.514
0.0GlnCys: 0.0 ± 0.0
0.442GlnAsp: 0.442 ± 0.479
3.092GlnGlu: 3.092 ± 1.23
0.883GlnPhe: 0.883 ± 0.43
2.65GlnGly: 2.65 ± 0.682
0.442GlnHis: 0.442 ± 0.386
1.325GlnIle: 1.325 ± 0.505
1.325GlnLys: 1.325 ± 0.789
7.509GlnLeu: 7.509 ± 2.68
2.208GlnMet: 2.208 ± 0.71
3.975GlnAsn: 3.975 ± 0.791
2.65GlnPro: 2.65 ± 1.232
1.767GlnGln: 1.767 ± 0.647
1.767GlnArg: 1.767 ± 0.818
4.417GlnSer: 4.417 ± 1.489
2.208GlnThr: 2.208 ± 0.82
2.208GlnVal: 2.208 ± 0.411
0.883GlnTrp: 0.883 ± 0.43
1.325GlnTyr: 1.325 ± 0.427
0.0GlnXaa: 0.0 ± 0.0
Arg
4.417ArgAla: 4.417 ± 0.798
1.767ArgCys: 1.767 ± 1.278
3.975ArgAsp: 3.975 ± 1.876
2.208ArgGlu: 2.208 ± 0.862
3.975ArgPhe: 3.975 ± 0.852
4.859ArgGly: 4.859 ± 1.728
2.208ArgHis: 2.208 ± 0.818
1.325ArgIle: 1.325 ± 0.804
3.534ArgLys: 3.534 ± 1.449
7.067ArgLeu: 7.067 ± 1.426
0.883ArgMet: 0.883 ± 0.732
0.883ArgAsn: 0.883 ± 0.514
2.208ArgPro: 2.208 ± 1.067
2.65ArgGln: 2.65 ± 1.143
7.509ArgArg: 7.509 ± 2.712
5.3ArgSer: 5.3 ± 2.661
2.65ArgThr: 2.65 ± 0.792
3.975ArgVal: 3.975 ± 1.472
0.442ArgTrp: 0.442 ± 0.41
2.65ArgTyr: 2.65 ± 0.581
0.0ArgXaa: 0.0 ± 0.0
Ser
3.534SerAla: 3.534 ± 1.665
1.325SerCys: 1.325 ± 0.715
4.859SerAsp: 4.859 ± 1.335
5.3SerGlu: 5.3 ± 1.005
3.975SerPhe: 3.975 ± 1.662
3.534SerGly: 3.534 ± 0.941
1.325SerHis: 1.325 ± 1.437
4.859SerIle: 4.859 ± 1.726
3.092SerLys: 3.092 ± 1.407
9.276SerLeu: 9.276 ± 2.101
0.442SerMet: 0.442 ± 0.335
4.417SerAsn: 4.417 ± 1.508
3.975SerPro: 3.975 ± 1.254
4.859SerGln: 4.859 ± 1.907
7.067SerArg: 7.067 ± 2.713
5.3SerSer: 5.3 ± 2.416
6.184SerThr: 6.184 ± 2.209
7.067SerVal: 7.067 ± 3.116
0.0SerTrp: 0.0 ± 0.0
0.442SerTyr: 0.442 ± 0.594
0.0SerXaa: 0.0 ± 0.0
Thr
2.65ThrAla: 2.65 ± 1.236
0.883ThrCys: 0.883 ± 0.43
1.325ThrAsp: 1.325 ± 0.799
4.859ThrGlu: 4.859 ± 1.424
3.975ThrPhe: 3.975 ± 1.944
4.859ThrGly: 4.859 ± 1.603
0.883ThrHis: 0.883 ± 0.43
2.208ThrIle: 2.208 ± 0.505
3.975ThrLys: 3.975 ± 1.98
7.067ThrLeu: 7.067 ± 1.661
2.65ThrMet: 2.65 ± 1.289
2.208ThrAsn: 2.208 ± 0.849
5.742ThrPro: 5.742 ± 1.942
1.767ThrGln: 1.767 ± 0.696
5.3ThrArg: 5.3 ± 1.344
3.975ThrSer: 3.975 ± 1.62
3.534ThrThr: 3.534 ± 1.205
3.534ThrVal: 3.534 ± 0.999
0.883ThrTrp: 0.883 ± 0.958
0.883ThrTyr: 0.883 ± 0.771
0.0ThrXaa: 0.0 ± 0.0
Val
2.65ValAla: 2.65 ± 1.091
0.883ValCys: 0.883 ± 0.543
4.859ValAsp: 4.859 ± 1.196
5.3ValGlu: 5.3 ± 1.633
2.208ValPhe: 2.208 ± 0.82
3.975ValGly: 3.975 ± 1.644
2.208ValHis: 2.208 ± 0.718
3.534ValIle: 3.534 ± 1.454
2.208ValLys: 2.208 ± 0.64
4.417ValLeu: 4.417 ± 1.441
0.0ValMet: 0.0 ± 0.0
1.325ValAsn: 1.325 ± 1.005
5.3ValPro: 5.3 ± 1.047
0.442ValGln: 0.442 ± 0.41
3.975ValArg: 3.975 ± 1.223
6.625ValSer: 6.625 ± 1.19
6.184ValThr: 6.184 ± 2.16
3.975ValVal: 3.975 ± 1.089
1.325ValTrp: 1.325 ± 0.745
1.325ValTyr: 1.325 ± 0.858
0.0ValXaa: 0.0 ± 0.0
Trp
0.883TrpAla: 0.883 ± 0.43
0.442TrpCys: 0.442 ± 0.386
0.442TrpAsp: 0.442 ± 0.335
0.883TrpGlu: 0.883 ± 0.43
0.0TrpPhe: 0.0 ± 0.0
0.442TrpGly: 0.442 ± 0.547
1.325TrpHis: 1.325 ± 0.87
0.442TrpIle: 0.442 ± 0.335
1.325TrpLys: 1.325 ± 0.789
1.325TrpLeu: 1.325 ± 0.745
0.0TrpMet: 0.0 ± 0.0
0.883TrpAsn: 0.883 ± 0.561
0.0TrpPro: 0.0 ± 0.0
1.325TrpGln: 1.325 ± 0.87
0.0TrpArg: 0.0 ± 0.0
0.883TrpSer: 0.883 ± 0.43
1.325TrpThr: 1.325 ± 1.079
1.325TrpVal: 1.325 ± 1.005
0.0TrpTrp: 0.0 ± 0.0
0.442TrpTyr: 0.442 ± 0.335
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.208TyrAla: 2.208 ± 1.129
0.883TyrCys: 0.883 ± 0.893
0.442TyrAsp: 0.442 ± 0.335
2.208TyrGlu: 2.208 ± 0.924
2.208TyrPhe: 2.208 ± 1.011
3.534TyrGly: 3.534 ± 0.871
0.442TyrHis: 0.442 ± 0.386
2.208TyrIle: 2.208 ± 0.958
1.325TyrLys: 1.325 ± 1.005
2.208TyrLeu: 2.208 ± 0.756
1.325TyrMet: 1.325 ± 0.629
0.883TyrAsn: 0.883 ± 0.475
0.883TyrPro: 0.883 ± 0.475
1.767TyrGln: 1.767 ± 1.003
1.767TyrArg: 1.767 ± 1.051
0.883TyrSer: 0.883 ± 0.82
1.767TyrThr: 1.767 ± 0.918
0.442TyrVal: 0.442 ± 0.386
0.442TyrTrp: 0.442 ± 0.386
2.208TyrTyr: 2.208 ± 1.246
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2265 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski