Amino acid dipepetide frequency for Pseudoramibacter alactolyticus ATCC 23263

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.259AlaAla: 12.259 ± 0.201
1.415AlaCys: 1.415 ± 0.057
6.312AlaAsp: 6.312 ± 0.114
6.153AlaGlu: 6.153 ± 0.127
3.992AlaPhe: 3.992 ± 0.096
8.155AlaGly: 8.155 ± 0.154
1.922AlaHis: 1.922 ± 0.054
6.56AlaIle: 6.56 ± 0.109
5.338AlaLys: 5.338 ± 0.1
9.873AlaLeu: 9.873 ± 0.129
3.246AlaMet: 3.246 ± 0.076
2.81AlaAsn: 2.81 ± 0.076
3.269AlaPro: 3.269 ± 0.064
3.206AlaGln: 3.206 ± 0.076
4.893AlaArg: 4.893 ± 0.098
4.591AlaSer: 4.591 ± 0.088
4.025AlaThr: 4.025 ± 0.092
8.096AlaVal: 8.096 ± 0.139
0.768AlaTrp: 0.768 ± 0.035
3.133AlaTyr: 3.133 ± 0.062
0.0AlaXaa: 0.0 ± 0.0
Cys
1.253CysAla: 1.253 ± 0.047
0.272CysCys: 0.272 ± 0.02
0.901CysAsp: 0.901 ± 0.037
0.828CysGlu: 0.828 ± 0.032
0.669CysPhe: 0.669 ± 0.03
1.475CysGly: 1.475 ± 0.048
0.372CysHis: 0.372 ± 0.027
0.826CysIle: 0.826 ± 0.035
0.558CysLys: 0.558 ± 0.033
1.184CysLeu: 1.184 ± 0.048
0.367CysMet: 0.367 ± 0.025
0.451CysAsn: 0.451 ± 0.025
0.697CysPro: 0.697 ± 0.035
0.381CysGln: 0.381 ± 0.026
0.853CysArg: 0.853 ± 0.034
0.684CysSer: 0.684 ± 0.031
0.687CysThr: 0.687 ± 0.03
0.989CysVal: 0.989 ± 0.034
0.132CysTrp: 0.132 ± 0.012
0.483CysTyr: 0.483 ± 0.025
0.0CysXaa: 0.0 ± 0.0
Asp
6.236AspAla: 6.236 ± 0.105
0.805AspCys: 0.805 ± 0.036
3.351AspAsp: 3.351 ± 0.1
3.894AspGlu: 3.894 ± 0.09
2.691AspPhe: 2.691 ± 0.058
4.456AspGly: 4.456 ± 0.093
1.39AspHis: 1.39 ± 0.047
4.07AspIle: 4.07 ± 0.078
2.95AspLys: 2.95 ± 0.077
5.211AspLeu: 5.211 ± 0.085
1.654AspMet: 1.654 ± 0.053
1.946AspAsn: 1.946 ± 0.054
2.454AspPro: 2.454 ± 0.057
1.95AspGln: 1.95 ± 0.06
3.296AspArg: 3.296 ± 0.083
2.5AspSer: 2.5 ± 0.063
2.832AspThr: 2.832 ± 0.074
4.18AspVal: 4.18 ± 0.075
0.676AspTrp: 0.676 ± 0.031
2.47AspTyr: 2.47 ± 0.066
0.0AspXaa: 0.0 ± 0.0
Glu
6.831GluAla: 6.831 ± 0.132
0.587GluCys: 0.587 ± 0.027
3.4GluAsp: 3.4 ± 0.076
3.929GluGlu: 3.929 ± 0.094
1.476GluPhe: 1.476 ± 0.044
3.657GluGly: 3.657 ± 0.074
1.249GluHis: 1.249 ± 0.044
4.279GluIle: 4.279 ± 0.083
4.913GluLys: 4.913 ± 0.094
4.872GluLeu: 4.872 ± 0.078
2.132GluMet: 2.132 ± 0.054
2.907GluAsn: 2.907 ± 0.073
1.777GluPro: 1.777 ± 0.057
2.164GluGln: 2.164 ± 0.064
3.428GluArg: 3.428 ± 0.074
2.801GluSer: 2.801 ± 0.067
3.746GluThr: 3.746 ± 0.078
3.643GluVal: 3.643 ± 0.082
0.483GluTrp: 0.483 ± 0.029
1.64GluTyr: 1.64 ± 0.053
0.0GluXaa: 0.0 ± 0.0
Phe
3.571PheAla: 3.571 ± 0.09
0.727PheCys: 0.727 ± 0.036
2.923PheAsp: 2.923 ± 0.065
2.467PheGlu: 2.467 ± 0.068
1.945PhePhe: 1.945 ± 0.066
3.322PheGly: 3.322 ± 0.079
0.726PheHis: 0.726 ± 0.028
2.568PheIle: 2.568 ± 0.067
2.116PheLys: 2.116 ± 0.056
3.347PheLeu: 3.347 ± 0.078
1.199PheMet: 1.199 ± 0.042
1.567PheAsn: 1.567 ± 0.048
1.445PhePro: 1.445 ± 0.043
1.065PheGln: 1.065 ± 0.037
1.717PheArg: 1.717 ± 0.057
2.502PheSer: 2.502 ± 0.062
1.999PheThr: 1.999 ± 0.054
2.801PheVal: 2.801 ± 0.076
0.468PheTrp: 0.468 ± 0.027
1.547PheTyr: 1.547 ± 0.059
0.0PheXaa: 0.0 ± 0.0
Gly
6.295GlyAla: 6.295 ± 0.122
1.266GlyCys: 1.266 ± 0.048
4.174GlyAsp: 4.174 ± 0.083
4.461GlyGlu: 4.461 ± 0.092
3.031GlyPhe: 3.031 ± 0.076
5.928GlyGly: 5.928 ± 0.121
1.601GlyHis: 1.601 ± 0.051
6.077GlyIle: 6.077 ± 0.105
4.932GlyLys: 4.932 ± 0.089
6.487GlyLeu: 6.487 ± 0.109
2.399GlyMet: 2.399 ± 0.069
2.515GlyAsn: 2.515 ± 0.069
1.889GlyPro: 1.889 ± 0.059
2.467GlyGln: 2.467 ± 0.059
4.548GlyArg: 4.548 ± 0.08
4.107GlySer: 4.107 ± 0.082
4.266GlyThr: 4.266 ± 0.104
5.384GlyVal: 5.384 ± 0.087
0.769GlyTrp: 0.769 ± 0.036
2.88GlyTyr: 2.88 ± 0.064
0.0GlyXaa: 0.0 ± 0.0
His
1.572HisAla: 1.572 ± 0.05
0.357HisCys: 0.357 ± 0.022
1.081HisAsp: 1.081 ± 0.037
0.988HisGlu: 0.988 ± 0.04
1.209HisPhe: 1.209 ± 0.045
1.451HisGly: 1.451 ± 0.043
0.649HisHis: 0.649 ± 0.034
1.376HisIle: 1.376 ± 0.043
0.889HisLys: 0.889 ± 0.036
2.062HisLeu: 2.062 ± 0.059
0.566HisMet: 0.566 ± 0.026
0.662HisAsn: 0.662 ± 0.036
1.147HisPro: 1.147 ± 0.047
0.845HisGln: 0.845 ± 0.043
1.396HisArg: 1.396 ± 0.05
1.02HisSer: 1.02 ± 0.038
0.988HisThr: 0.988 ± 0.045
1.267HisVal: 1.267 ± 0.04
0.235HisTrp: 0.235 ± 0.019
0.925HisTyr: 0.925 ± 0.035
0.0HisXaa: 0.0 ± 0.0
Ile
7.246IleAla: 7.246 ± 0.117
1.166IleCys: 1.166 ± 0.043
4.436IleAsp: 4.436 ± 0.084
4.091IleGlu: 4.091 ± 0.085
2.88IlePhe: 2.88 ± 0.08
5.583IleGly: 5.583 ± 0.12
1.368IleHis: 1.368 ± 0.052
4.355IleIle: 4.355 ± 0.103
3.753IleLys: 3.753 ± 0.089
6.004IleLeu: 6.004 ± 0.107
1.781IleMet: 1.781 ± 0.045
2.612IleAsn: 2.612 ± 0.06
3.06IlePro: 3.06 ± 0.066
2.012IleGln: 2.012 ± 0.057
3.732IleArg: 3.732 ± 0.081
3.881IleSer: 3.881 ± 0.084
3.707IleThr: 3.707 ± 0.084
4.98IleVal: 4.98 ± 0.098
0.504IleTrp: 0.504 ± 0.028
2.26IleTyr: 2.26 ± 0.066
0.0IleXaa: 0.0 ± 0.0
Lys
5.873LysAla: 5.873 ± 0.114
0.514LysCys: 0.514 ± 0.03
3.372LysAsp: 3.372 ± 0.079
3.878LysGlu: 3.878 ± 0.091
1.516LysPhe: 1.516 ± 0.053
3.776LysGly: 3.776 ± 0.076
1.087LysHis: 1.087 ± 0.04
4.562LysIle: 4.562 ± 0.102
4.896LysLys: 4.896 ± 0.126
4.395LysLeu: 4.395 ± 0.075
2.006LysMet: 2.006 ± 0.062
3.047LysAsn: 3.047 ± 0.088
2.033LysPro: 2.033 ± 0.057
2.192LysGln: 2.192 ± 0.063
3.447LysArg: 3.447 ± 0.086
3.073LysSer: 3.073 ± 0.076
4.012LysThr: 4.012 ± 0.086
3.657LysVal: 3.657 ± 0.084
0.55LysTrp: 0.55 ± 0.029
1.84LysTyr: 1.84 ± 0.049
0.0LysXaa: 0.0 ± 0.0
Leu
8.948LeuAla: 8.948 ± 0.138
1.413LeuCys: 1.413 ± 0.047
5.012LeuAsp: 5.012 ± 0.096
4.733LeuGlu: 4.733 ± 0.092
3.614LeuPhe: 3.614 ± 0.082
6.221LeuGly: 6.221 ± 0.099
1.529LeuHis: 1.529 ± 0.052
6.057LeuIle: 6.057 ± 0.094
5.821LeuLys: 5.821 ± 0.095
7.79LeuLeu: 7.79 ± 0.138
2.903LeuMet: 2.903 ± 0.058
3.374LeuAsn: 3.374 ± 0.06
4.084LeuPro: 4.084 ± 0.079
2.51LeuGln: 2.51 ± 0.061
4.313LeuArg: 4.313 ± 0.093
6.023LeuSer: 6.023 ± 0.105
5.54LeuThr: 5.54 ± 0.089
5.274LeuVal: 5.274 ± 0.089
0.831LeuTrp: 0.831 ± 0.038
2.745LeuTyr: 2.745 ± 0.069
0.0LeuXaa: 0.0 ± 0.0
Met
3.71MetAla: 3.71 ± 0.076
0.282MetCys: 0.282 ± 0.022
1.884MetAsp: 1.884 ± 0.058
1.495MetGlu: 1.495 ± 0.049
0.863MetPhe: 0.863 ± 0.038
2.232MetGly: 2.232 ± 0.058
0.604MetHis: 0.604 ± 0.029
2.21MetIle: 2.21 ± 0.054
2.029MetLys: 2.029 ± 0.057
2.645MetLeu: 2.645 ± 0.057
1.042MetMet: 1.042 ± 0.043
1.402MetAsn: 1.402 ± 0.048
1.366MetPro: 1.366 ± 0.048
1.134MetGln: 1.134 ± 0.045
1.774MetArg: 1.774 ± 0.052
1.551MetSer: 1.551 ± 0.048
1.949MetThr: 1.949 ± 0.055
1.995MetVal: 1.995 ± 0.056
0.165MetTrp: 0.165 ± 0.017
0.637MetTyr: 0.637 ± 0.03
0.0MetXaa: 0.0 ± 0.0
Asn
3.613AsnAla: 3.613 ± 0.09
0.507AsnCys: 0.507 ± 0.029
1.939AsnAsp: 1.939 ± 0.051
1.995AsnGlu: 1.995 ± 0.055
1.386AsnPhe: 1.386 ± 0.048
2.936AsnGly: 2.936 ± 0.077
0.894AsnHis: 0.894 ± 0.039
2.686AsnIle: 2.686 ± 0.077
1.945AsnLys: 1.945 ± 0.066
3.258AsnLeu: 3.258 ± 0.071
1.031AsnMet: 1.031 ± 0.039
1.416AsnAsn: 1.416 ± 0.06
1.869AsnPro: 1.869 ± 0.051
1.426AsnGln: 1.426 ± 0.044
2.21AsnArg: 2.21 ± 0.055
1.565AsnSer: 1.565 ± 0.058
2.045AsnThr: 2.045 ± 0.063
2.527AsnVal: 2.527 ± 0.067
0.41AsnTrp: 0.41 ± 0.025
1.266AsnTyr: 1.266 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
3.915ProAla: 3.915 ± 0.082
0.444ProCys: 0.444 ± 0.024
2.635ProAsp: 2.635 ± 0.067
3.337ProGlu: 3.337 ± 0.075
1.746ProPhe: 1.746 ± 0.05
3.06ProGly: 3.06 ± 0.072
0.725ProHis: 0.725 ± 0.032
2.459ProIle: 2.459 ± 0.056
2.177ProLys: 2.177 ± 0.063
3.076ProLeu: 3.076 ± 0.067
1.148ProMet: 1.148 ± 0.042
1.306ProAsn: 1.306 ± 0.047
1.064ProPro: 1.064 ± 0.051
1.146ProGln: 1.146 ± 0.039
1.611ProArg: 1.611 ± 0.053
1.87ProSer: 1.87 ± 0.059
1.756ProThr: 1.756 ± 0.057
3.153ProVal: 3.153 ± 0.064
0.387ProTrp: 0.387 ± 0.024
1.429ProTyr: 1.429 ± 0.045
0.0ProXaa: 0.0 ± 0.0
Gln
3.242GlnAla: 3.242 ± 0.07
0.391GlnCys: 0.391 ± 0.023
1.522GlnAsp: 1.522 ± 0.043
1.667GlnGlu: 1.667 ± 0.055
1.227GlnPhe: 1.227 ± 0.047
1.884GlnGly: 1.884 ± 0.052
0.561GlnHis: 0.561 ± 0.027
2.595GlnIle: 2.595 ± 0.071
2.737GlnLys: 2.737 ± 0.081
2.881GlnLeu: 2.881 ± 0.072
1.312GlnMet: 1.312 ± 0.048
1.532GlnAsn: 1.532 ± 0.048
1.12GlnPro: 1.12 ± 0.043
1.193GlnGln: 1.193 ± 0.045
1.806GlnArg: 1.806 ± 0.055
1.852GlnSer: 1.852 ± 0.059
2.029GlnThr: 2.029 ± 0.056
2.169GlnVal: 2.169 ± 0.059
0.347GlnTrp: 0.347 ± 0.024
1.147GlnTyr: 1.147 ± 0.047
0.0GlnXaa: 0.0 ± 0.0
Arg
4.621ArgAla: 4.621 ± 0.106
0.825ArgCys: 0.825 ± 0.042
2.914ArgAsp: 2.914 ± 0.074
3.775ArgGlu: 3.775 ± 0.081
2.285ArgPhe: 2.285 ± 0.055
3.604ArgGly: 3.604 ± 0.083
1.359ArgHis: 1.359 ± 0.046
3.821ArgIle: 3.821 ± 0.082
3.341ArgLys: 3.341 ± 0.078
5.148ArgLeu: 5.148 ± 0.108
1.78ArgMet: 1.78 ± 0.051
1.747ArgAsn: 1.747 ± 0.045
2.085ArgPro: 2.085 ± 0.068
2.401ArgGln: 2.401 ± 0.07
4.247ArgArg: 4.247 ± 0.11
2.642ArgSer: 2.642 ± 0.075
2.529ArgThr: 2.529 ± 0.065
3.573ArgVal: 3.573 ± 0.086
0.573ArgTrp: 0.573 ± 0.029
2.008ArgTyr: 2.008 ± 0.051
0.0ArgXaa: 0.0 ± 0.0
Ser
4.892SerAla: 4.892 ± 0.095
0.674SerCys: 0.674 ± 0.033
3.178SerAsp: 3.178 ± 0.064
3.392SerGlu: 3.392 ± 0.079
2.263SerPhe: 2.263 ± 0.066
4.933SerGly: 4.933 ± 0.097
1.153SerHis: 1.153 ± 0.042
3.202SerIle: 3.202 ± 0.072
2.676SerLys: 2.676 ± 0.074
4.622SerLeu: 4.622 ± 0.101
1.549SerMet: 1.549 ± 0.048
1.66SerAsn: 1.66 ± 0.05
1.956SerPro: 1.956 ± 0.057
1.673SerGln: 1.673 ± 0.048
3.047SerArg: 3.047 ± 0.071
2.742SerSer: 2.742 ± 0.08
2.404SerThr: 2.404 ± 0.065
3.931SerVal: 3.931 ± 0.084
0.46SerTrp: 0.46 ± 0.026
1.615SerTyr: 1.615 ± 0.067
0.0SerXaa: 0.0 ± 0.0
Thr
5.822ThrAla: 5.822 ± 0.107
0.626ThrCys: 0.626 ± 0.025
3.189ThrAsp: 3.189 ± 0.065
2.873ThrGlu: 2.873 ± 0.074
2.202ThrPhe: 2.202 ± 0.058
4.694ThrGly: 4.694 ± 0.092
1.055ThrHis: 1.055 ± 0.04
3.896ThrIle: 3.896 ± 0.079
2.737ThrLys: 2.737 ± 0.068
5.063ThrLeu: 5.063 ± 0.092
1.549ThrMet: 1.549 ± 0.051
1.763ThrAsn: 1.763 ± 0.055
2.464ThrPro: 2.464 ± 0.063
1.512ThrGln: 1.512 ± 0.054
2.513ThrArg: 2.513 ± 0.064
2.506ThrSer: 2.506 ± 0.068
2.938ThrThr: 2.938 ± 0.074
4.196ThrVal: 4.196 ± 0.092
0.431ThrTrp: 0.431 ± 0.029
1.694ThrTyr: 1.694 ± 0.061
0.0ThrXaa: 0.0 ± 0.0
Val
6.558ValAla: 6.558 ± 0.122
1.12ValCys: 1.12 ± 0.04
4.084ValAsp: 4.084 ± 0.081
3.593ValGlu: 3.593 ± 0.071
2.993ValPhe: 2.993 ± 0.074
4.81ValGly: 4.81 ± 0.096
1.28ValHis: 1.28 ± 0.047
5.211ValIle: 5.211 ± 0.096
3.875ValLys: 3.875 ± 0.091
6.594ValLeu: 6.594 ± 0.106
2.238ValMet: 2.238 ± 0.062
2.61ValAsn: 2.61 ± 0.066
2.903ValPro: 2.903 ± 0.08
1.992ValGln: 1.992 ± 0.053
3.517ValArg: 3.517 ± 0.084
4.095ValSer: 4.095 ± 0.069
4.115ValThr: 4.115 ± 0.095
5.114ValVal: 5.114 ± 0.092
0.556ValTrp: 0.556 ± 0.029
2.273ValTyr: 2.273 ± 0.06
0.0ValXaa: 0.0 ± 0.0
Trp
0.677TrpAla: 0.677 ± 0.033
0.156TrpCys: 0.156 ± 0.015
0.54TrpAsp: 0.54 ± 0.031
0.503TrpGlu: 0.503 ± 0.03
0.395TrpPhe: 0.395 ± 0.025
0.621TrpGly: 0.621 ± 0.03
0.256TrpHis: 0.256 ± 0.02
0.627TrpIle: 0.627 ± 0.03
0.458TrpLys: 0.458 ± 0.028
0.972TrpLeu: 0.972 ± 0.043
0.315TrpMet: 0.315 ± 0.024
0.359TrpAsn: 0.359 ± 0.022
0.326TrpPro: 0.326 ± 0.022
0.547TrpGln: 0.547 ± 0.026
0.629TrpArg: 0.629 ± 0.031
0.395TrpSer: 0.395 ± 0.024
0.442TrpThr: 0.442 ± 0.025
0.56TrpVal: 0.56 ± 0.03
0.1TrpTrp: 0.1 ± 0.011
0.289TrpTyr: 0.289 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.883TyrAla: 2.883 ± 0.065
0.517TyrCys: 0.517 ± 0.03
2.167TyrAsp: 2.167 ± 0.06
1.863TyrGlu: 1.863 ± 0.059
1.638TyrPhe: 1.638 ± 0.046
2.675TyrGly: 2.675 ± 0.063
0.904TyrHis: 0.904 ± 0.034
1.975TyrIle: 1.975 ± 0.05
1.587TyrLys: 1.587 ± 0.049
3.251TyrLeu: 3.251 ± 0.078
0.752TyrMet: 0.752 ± 0.035
1.237TyrAsn: 1.237 ± 0.041
1.432TyrPro: 1.432 ± 0.055
1.396TyrGln: 1.396 ± 0.054
2.3TyrArg: 2.3 ± 0.059
1.622TyrSer: 1.622 ± 0.049
1.713TyrThr: 1.713 ± 0.053
2.041TyrVal: 2.041 ± 0.048
0.329TyrTrp: 0.329 ± 0.02
1.388TyrTyr: 1.388 ± 0.044
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2514 proteins (698337 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski