Amino acid dipepetide frequency for Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex octospinosus echinatior)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.122AlaAla: 5.122 ± 0.055	1.225AlaCys: 1.225 ± 0.027	2.88AlaAsp: 2.88 ± 0.027	3.848AlaGlu: 3.848 ± 0.03	2.124AlaPhe: 2.124 ± 0.023	3.347AlaGly: 3.347 ± 0.031	1.419AlaHis: 1.419 ± 0.017	3.712AlaIle: 3.712 ± 0.028	3.673AlaLys: 3.673 ± 0.035	5.632AlaLeu: 5.632 ± 0.043	1.525AlaMet: 1.525 ± 0.018	2.777AlaAsn: 2.777 ± 0.027	2.689AlaPro: 2.689 ± 0.031	2.288AlaGln: 2.288 ± 0.025	3.668AlaArg: 3.668 ± 0.032	4.887AlaSer: 4.887 ± 0.035	3.974AlaThr: 3.974 ± 0.03	3.911AlaVal: 3.911 ± 0.03	0.634AlaTrp: 0.634 ± 0.013	1.636AlaTyr: 1.636 ± 0.018	0.001AlaXaa: 0.001 ± 0.0
Cys	1.15CysAla: 1.15 ± 0.016	0.491CysCys: 0.491 ± 0.011	1.136CysAsp: 1.136 ± 0.022	1.189CysGlu: 1.189 ± 0.022	0.742CysPhe: 0.742 ± 0.012	1.317CysGly: 1.317 ± 0.034	0.542CysHis: 0.542 ± 0.011	1.23CysIle: 1.23 ± 0.026	1.172CysLys: 1.172 ± 0.022	1.789CysLeu: 1.789 ± 0.028	0.438CysMet: 0.438 ± 0.008	1.013CysAsn: 1.013 ± 0.021	1.011CysPro: 1.011 ± 0.036	0.788CysGln: 0.788 ± 0.02	1.219CysArg: 1.219 ± 0.035	1.58CysSer: 1.58 ± 0.031	1.174CysThr: 1.174 ± 0.028	1.234CysVal: 1.234 ± 0.024	0.232CysTrp: 0.232 ± 0.007	0.599CysTyr: 0.599 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	3.075AspAla: 3.075 ± 0.027	1.016AspCys: 1.016 ± 0.024	3.677AspAsp: 3.677 ± 0.041	4.141AspGlu: 4.141 ± 0.034	2.057AspPhe: 2.057 ± 0.02	3.003AspGly: 3.003 ± 0.035	1.129AspHis: 1.129 ± 0.014	3.727AspIle: 3.727 ± 0.03	3.394AspLys: 3.394 ± 0.038	4.658AspLeu: 4.658 ± 0.033	1.262AspMet: 1.262 ± 0.014	2.867AspAsn: 2.867 ± 0.031	2.308AspPro: 2.308 ± 0.033	1.676AspGln: 1.676 ± 0.021	2.877AspArg: 2.877 ± 0.029	4.289AspSer: 4.289 ± 0.033	3.023AspThr: 3.023 ± 0.027	3.579AspVal: 3.579 ± 0.028	0.607AspTrp: 0.607 ± 0.01	1.808AspTyr: 1.808 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	3.888GluAla: 3.888 ± 0.032	1.219GluCys: 1.219 ± 0.037	4.156GluAsp: 4.156 ± 0.034	6.479GluGlu: 6.479 ± 0.089	2.075GluPhe: 2.075 ± 0.02	2.97GluGly: 2.97 ± 0.034	1.501GluHis: 1.501 ± 0.018	4.349GluIle: 4.349 ± 0.043	5.375GluLys: 5.375 ± 0.053	5.697GluLeu: 5.697 ± 0.047	1.659GluMet: 1.659 ± 0.02	3.91GluAsn: 3.91 ± 0.033	2.328GluPro: 2.328 ± 0.025	2.771GluGln: 2.771 ± 0.029	4.285GluArg: 4.285 ± 0.04	4.652GluSer: 4.652 ± 0.04	4.007GluThr: 4.007 ± 0.039	3.553GluVal: 3.553 ± 0.031	0.728GluTrp: 0.728 ± 0.01	1.944GluTyr: 1.944 ± 0.02	0.001GluXaa: 0.001 ± 0.0
Phe	2.135PheAla: 2.135 ± 0.021	0.811PheCys: 0.811 ± 0.013	1.989PheAsp: 1.989 ± 0.022	2.15PheGlu: 2.15 ± 0.025	1.521PhePhe: 1.521 ± 0.02	2.081PheGly: 2.081 ± 0.022	0.979PheHis: 0.979 ± 0.013	2.112PheIle: 2.112 ± 0.022	2.016PheLys: 2.016 ± 0.02	3.534PheLeu: 3.534 ± 0.033	0.813PheMet: 0.813 ± 0.013	1.742PheAsn: 1.742 ± 0.019	1.646PhePro: 1.646 ± 0.018	1.378PheGln: 1.378 ± 0.017	1.934PheArg: 1.934 ± 0.02	2.802PheSer: 2.802 ± 0.023	2.069PheThr: 2.069 ± 0.02	2.337PheVal: 2.337 ± 0.024	0.425PheTrp: 0.425 ± 0.01	1.286PheTyr: 1.286 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	3.061GlyAla: 3.061 ± 0.032	1.026GlyCys: 1.026 ± 0.017	2.803GlyAsp: 2.803 ± 0.031	3.108GlyGlu: 3.108 ± 0.034	2.022GlyPhe: 2.022 ± 0.025	4.214GlyGly: 4.214 ± 0.063	1.369GlyHis: 1.369 ± 0.019	3.316GlyIle: 3.316 ± 0.027	3.302GlyLys: 3.302 ± 0.027	4.333GlyLeu: 4.333 ± 0.042	1.225GlyMet: 1.225 ± 0.016	2.705GlyAsn: 2.705 ± 0.029	2.3GlyPro: 2.3 ± 0.042	1.972GlyGln: 1.972 ± 0.023	3.278GlyArg: 3.278 ± 0.031	4.412GlySer: 4.412 ± 0.047	3.18GlyThr: 3.18 ± 0.025	3.129GlyVal: 3.129 ± 0.027	0.646GlyTrp: 0.646 ± 0.011	1.874GlyTyr: 1.874 ± 0.026	0.001GlyXaa: 0.001 ± 0.0
His	1.445HisAla: 1.445 ± 0.017	0.598HisCys: 0.598 ± 0.011	1.182HisAsp: 1.182 ± 0.013	1.428HisGlu: 1.428 ± 0.017	0.955HisPhe: 0.955 ± 0.014	1.399HisGly: 1.399 ± 0.019	1.05HisHis: 1.05 ± 0.023	1.464HisIle: 1.464 ± 0.019	1.341HisLys: 1.341 ± 0.017	2.371HisLeu: 2.371 ± 0.023	0.603HisMet: 0.603 ± 0.012	1.186HisAsn: 1.186 ± 0.014	1.389HisPro: 1.389 ± 0.016	1.099HisGln: 1.099 ± 0.018	1.621HisArg: 1.621 ± 0.018	1.987HisSer: 1.987 ± 0.02	1.377HisThr: 1.377 ± 0.016	1.597HisVal: 1.597 ± 0.014	0.296HisTrp: 0.296 ± 0.007	0.864HisTyr: 0.864 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.906IleAla: 3.906 ± 0.029	1.313IleCys: 1.313 ± 0.026	3.4IleAsp: 3.4 ± 0.024	3.992IleGlu: 3.992 ± 0.039	2.382IlePhe: 2.382 ± 0.024	3.061IleGly: 3.061 ± 0.029	1.442IleHis: 1.442 ± 0.019	3.775IleIle: 3.775 ± 0.032	3.828IleLys: 3.828 ± 0.039	5.712IleLeu: 5.712 ± 0.042	1.395IleMet: 1.395 ± 0.019	3.154IleAsn: 3.154 ± 0.032	3.004IlePro: 3.004 ± 0.023	2.388IleGln: 2.388 ± 0.021	3.141IleArg: 3.141 ± 0.023	4.847IleSer: 4.847 ± 0.034	3.614IleThr: 3.614 ± 0.036	3.794IleVal: 3.794 ± 0.029	0.619IleTrp: 0.619 ± 0.012	1.927IleTyr: 1.927 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.301LysAla: 3.301 ± 0.031	1.234LysCys: 1.234 ± 0.025	3.612LysAsp: 3.612 ± 0.048	5.093LysGlu: 5.093 ± 0.062	2.131LysPhe: 2.131 ± 0.021	2.622LysGly: 2.622 ± 0.031	1.525LysHis: 1.525 ± 0.018	4.151LysIle: 4.151 ± 0.043	5.493LysLys: 5.493 ± 0.063	5.737LysLeu: 5.737 ± 0.038	1.56LysMet: 1.56 ± 0.016	3.479LysAsn: 3.479 ± 0.031	2.707LysPro: 2.707 ± 0.044	2.718LysGln: 2.718 ± 0.029	4.167LysArg: 4.167 ± 0.032	4.818LysSer: 4.818 ± 0.05	3.645LysThr: 3.645 ± 0.031	3.369LysVal: 3.369 ± 0.033	0.708LysTrp: 0.708 ± 0.011	2.165LysTyr: 2.165 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	5.773LeuAla: 5.773 ± 0.042	1.82LeuCys: 1.82 ± 0.021	4.701LeuAsp: 4.701 ± 0.039	5.983LeuGlu: 5.983 ± 0.05	3.16LeuPhe: 3.16 ± 0.034	4.287LeuGly: 4.287 ± 0.036	2.499LeuHis: 2.499 ± 0.025	4.887LeuIle: 4.887 ± 0.035	5.916LeuLys: 5.916 ± 0.045	8.713LeuLeu: 8.713 ± 0.065	2.031LeuMet: 2.031 ± 0.021	4.281LeuAsn: 4.281 ± 0.038	4.762LeuPro: 4.762 ± 0.036	4.398LeuGln: 4.398 ± 0.034	5.565LeuArg: 5.565 ± 0.041	7.24LeuSer: 7.24 ± 0.046	5.106LeuThr: 5.106 ± 0.037	4.829LeuVal: 4.829 ± 0.034	0.938LeuTrp: 0.938 ± 0.015	2.73LeuTyr: 2.73 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	1.566MetAla: 1.566 ± 0.018	0.438MetCys: 0.438 ± 0.009	1.314MetAsp: 1.314 ± 0.016	1.725MetGlu: 1.725 ± 0.016	0.821MetPhe: 0.821 ± 0.014	1.134MetGly: 1.134 ± 0.017	0.567MetHis: 0.567 ± 0.01	1.351MetIle: 1.351 ± 0.015	1.617MetLys: 1.617 ± 0.017	2.099MetLeu: 2.099 ± 0.023	0.646MetMet: 0.646 ± 0.01	1.136MetAsn: 1.136 ± 0.016	1.158MetPro: 1.158 ± 0.017	1.1MetGln: 1.1 ± 0.016	1.325MetArg: 1.325 ± 0.016	1.83MetSer: 1.83 ± 0.02	1.37MetThr: 1.37 ± 0.015	1.19MetVal: 1.19 ± 0.015	0.243MetTrp: 0.243 ± 0.007	0.721MetTyr: 0.721 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.036AsnAla: 3.036 ± 0.026	0.96AsnCys: 0.96 ± 0.019	2.887AsnAsp: 2.887 ± 0.029	3.381AsnGlu: 3.381 ± 0.029	1.862AsnPhe: 1.862 ± 0.019	2.879AsnGly: 2.879 ± 0.025	1.193AsnHis: 1.193 ± 0.017	3.605AsnIle: 3.605 ± 0.03	3.185AsnLys: 3.185 ± 0.03	4.488AsnLeu: 4.488 ± 0.04	1.254AsnMet: 1.254 ± 0.018	3.292AsnAsn: 3.292 ± 0.038	2.24AsnPro: 2.24 ± 0.032	1.925AsnGln: 1.925 ± 0.024	2.533AsnArg: 2.533 ± 0.023	4.037AsnSer: 4.037 ± 0.036	2.909AsnThr: 2.909 ± 0.027	3.476AsnVal: 3.476 ± 0.029	0.56AsnTrp: 0.56 ± 0.009	1.684AsnTyr: 1.684 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	2.932ProAla: 2.932 ± 0.03	0.846ProCys: 0.846 ± 0.043	2.403ProAsp: 2.403 ± 0.023	3.087ProGlu: 3.087 ± 0.039	1.623ProPhe: 1.623 ± 0.019	2.739ProGly: 2.739 ± 0.057	1.238ProHis: 1.238 ± 0.017	2.743ProIle: 2.743 ± 0.028	2.639ProLys: 2.639 ± 0.032	4.089ProLeu: 4.089 ± 0.026	1.023ProMet: 1.023 ± 0.015	2.237ProAsn: 2.237 ± 0.029	4.082ProPro: 4.082 ± 0.066	1.983ProGln: 1.983 ± 0.029	2.814ProArg: 2.814 ± 0.024	4.361ProSer: 4.361 ± 0.041	3.137ProThr: 3.137 ± 0.03	2.996ProVal: 2.996 ± 0.026	0.504ProTrp: 0.504 ± 0.009	1.497ProTyr: 1.497 ± 0.019	0.001ProXaa: 0.001 ± 0.0
Gln	2.364GlnAla: 2.364 ± 0.025	0.823GlnCys: 0.823 ± 0.024	1.957GlnAsp: 1.957 ± 0.019	2.905GlnGlu: 2.905 ± 0.031	1.348GlnPhe: 1.348 ± 0.016	1.773GlnGly: 1.773 ± 0.024	1.243GlnHis: 1.243 ± 0.017	2.372GlnIle: 2.372 ± 0.023	2.645GlnLys: 2.645 ± 0.024	3.812GlnLeu: 3.812 ± 0.037	0.996GlnMet: 0.996 ± 0.013	2.239GlnAsn: 2.239 ± 0.023	1.965GlnPro: 1.965 ± 0.025	3.316GlnGln: 3.316 ± 0.071	2.622GlnArg: 2.622 ± 0.023	3.141GlnSer: 3.141 ± 0.034	2.336GlnThr: 2.336 ± 0.025	2.182GlnVal: 2.182 ± 0.024	0.465GlnTrp: 0.465 ± 0.01	1.291GlnTyr: 1.291 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	3.389ArgAla: 3.389 ± 0.031	1.206ArgCys: 1.206 ± 0.022	3.189ArgAsp: 3.189 ± 0.03	4.05ArgGlu: 4.05 ± 0.037	2.062ArgPhe: 2.062 ± 0.022	3.199ArgGly: 3.199 ± 0.034	1.65ArgHis: 1.65 ± 0.018	3.369ArgIle: 3.369 ± 0.028	4.165ArgLys: 4.165 ± 0.028	5.248ArgLeu: 5.248 ± 0.039	1.35ArgMet: 1.35 ± 0.017	3.062ArgAsn: 3.062 ± 0.025	2.655ArgPro: 2.655 ± 0.036	2.454ArgGln: 2.454 ± 0.021	4.871ArgArg: 4.871 ± 0.046	4.757ArgSer: 4.757 ± 0.042	3.179ArgThr: 3.179 ± 0.025	3.136ArgVal: 3.136 ± 0.025	0.693ArgTrp: 0.693 ± 0.012	1.876ArgTyr: 1.876 ± 0.021	0.001ArgXaa: 0.001 ± 0.0
Ser	4.677SerAla: 4.677 ± 0.036	1.54SerCys: 1.54 ± 0.031	4.373SerAsp: 4.373 ± 0.028	4.811SerGlu: 4.811 ± 0.038	2.757SerPhe: 2.757 ± 0.026	4.66SerGly: 4.66 ± 0.037	1.949SerHis: 1.949 ± 0.021	4.552SerIle: 4.552 ± 0.035	4.707SerLys: 4.707 ± 0.039	7.057SerLeu: 7.057 ± 0.041	1.809SerMet: 1.809 ± 0.018	4.259SerAsn: 4.259 ± 0.03	4.503SerPro: 4.503 ± 0.054	3.206SerGln: 3.206 ± 0.031	4.768SerArg: 4.768 ± 0.041	8.552SerSer: 8.552 ± 0.077	5.402SerThr: 5.402 ± 0.047	4.736SerVal: 4.736 ± 0.032	0.842SerTrp: 0.842 ± 0.015	2.282SerTyr: 2.282 ± 0.021	0.001SerXaa: 0.001 ± 0.0
Thr	3.815ThrAla: 3.815 ± 0.032	1.238ThrCys: 1.238 ± 0.026	3.008ThrAsp: 3.008 ± 0.025	3.795ThrGlu: 3.795 ± 0.047	2.142ThrPhe: 2.142 ± 0.019	3.273ThrGly: 3.273 ± 0.031	1.305ThrHis: 1.305 ± 0.015	3.711ThrIle: 3.711 ± 0.029	3.536ThrLys: 3.536 ± 0.042	5.384ThrLeu: 5.384 ± 0.043	1.387ThrMet: 1.387 ± 0.017	2.971ThrAsn: 2.971 ± 0.028	3.248ThrPro: 3.248 ± 0.035	2.182ThrGln: 2.182 ± 0.021	3.13ThrArg: 3.13 ± 0.027	5.457ThrSer: 5.457 ± 0.043	4.419ThrThr: 4.419 ± 0.064	3.824ThrVal: 3.824 ± 0.033	0.661ThrTrp: 0.661 ± 0.01	1.758ThrTyr: 1.758 ± 0.022	0.001ThrXaa: 0.001 ± 0.0
Val	4.037ValAla: 4.037 ± 0.028	1.31ValCys: 1.31 ± 0.025	3.183ValAsp: 3.183 ± 0.026	3.786ValGlu: 3.786 ± 0.031	2.15ValPhe: 2.15 ± 0.023	2.982ValGly: 2.982 ± 0.023	1.465ValHis: 1.465 ± 0.015	3.608ValIle: 3.608 ± 0.028	3.607ValLys: 3.607 ± 0.03	5.288ValLeu: 5.288 ± 0.034	1.34ValMet: 1.34 ± 0.016	2.817ValAsn: 2.817 ± 0.028	3.104ValPro: 3.104 ± 0.028	2.438ValGln: 2.438 ± 0.025	3.191ValArg: 3.191 ± 0.026	4.635ValSer: 4.635 ± 0.032	3.939ValThr: 3.939 ± 0.034	3.704ValVal: 3.704 ± 0.032	0.632ValTrp: 0.632 ± 0.013	1.84ValTyr: 1.84 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.553TrpAla: 0.553 ± 0.011	0.23TrpCys: 0.23 ± 0.006	0.584TrpAsp: 0.584 ± 0.011	0.648TrpGlu: 0.648 ± 0.01	0.463TrpPhe: 0.463 ± 0.009	0.523TrpGly: 0.523 ± 0.009	0.305TrpHis: 0.305 ± 0.008	0.754TrpIle: 0.754 ± 0.013	0.754TrpLys: 0.754 ± 0.015	1.112TrpLeu: 1.112 ± 0.016	0.281TrpMet: 0.281 ± 0.008	0.594TrpAsn: 0.594 ± 0.01	0.433TrpPro: 0.433 ± 0.009	0.481TrpGln: 0.481 ± 0.009	0.748TrpArg: 0.748 ± 0.011	0.822TrpSer: 0.822 ± 0.012	0.61TrpThr: 0.61 ± 0.011	0.534TrpVal: 0.534 ± 0.01	0.187TrpTrp: 0.187 ± 0.006	0.37TrpTyr: 0.37 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.745TyrAla: 1.745 ± 0.02	0.703TyrCys: 0.703 ± 0.011	1.738TyrAsp: 1.738 ± 0.019	1.947TyrGlu: 1.947 ± 0.019	1.364TyrPhe: 1.364 ± 0.017	1.814TyrGly: 1.814 ± 0.023	0.885TyrHis: 0.885 ± 0.013	1.905TyrIle: 1.905 ± 0.024	1.868TyrLys: 1.868 ± 0.02	2.868TyrLeu: 2.868 ± 0.026	0.755TyrMet: 0.755 ± 0.012	1.662TyrAsn: 1.662 ± 0.021	1.443TyrPro: 1.443 ± 0.02	1.238TyrGln: 1.238 ± 0.019	1.801TyrArg: 1.801 ± 0.019	2.336TyrSer: 2.336 ± 0.026	1.773TyrThr: 1.773 ± 0.018	1.944TyrVal: 1.944 ± 0.019	0.365TyrTrp: 0.365 ± 0.01	1.202TyrTyr: 1.202 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.257XaaXaa: 0.257 ± 0.076

Statistics based on 13962 proteins (6253196 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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