Amino acid dipepetide frequency for Candidatus Competibacter denitrificans Run_A_D11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.851AlaAla: 13.851 ± 0.167	1.148AlaCys: 1.148 ± 0.031	6.035AlaAsp: 6.035 ± 0.07	6.954AlaGlu: 6.954 ± 0.093	3.615AlaPhe: 3.615 ± 0.052	8.668AlaGly: 8.668 ± 0.102	2.351AlaHis: 2.351 ± 0.052	5.676AlaIle: 5.676 ± 0.065	3.733AlaLys: 3.733 ± 0.072	13.733AlaLeu: 13.733 ± 0.14	2.574AlaMet: 2.574 ± 0.045	3.054AlaAsn: 3.054 ± 0.056	4.752AlaPro: 4.752 ± 0.075	4.491AlaGln: 4.491 ± 0.074	7.541AlaArg: 7.541 ± 0.103	5.202AlaSer: 5.202 ± 0.068	5.951AlaThr: 5.951 ± 0.082	8.005AlaVal: 8.005 ± 0.085	1.65AlaTrp: 1.65 ± 0.039	2.496AlaTyr: 2.496 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.013CysAla: 1.013 ± 0.034	0.137CysCys: 0.137 ± 0.011	0.541CysAsp: 0.541 ± 0.023	0.527CysGlu: 0.527 ± 0.019	0.39CysPhe: 0.39 ± 0.017	0.961CysGly: 0.961 ± 0.027	0.304CysHis: 0.304 ± 0.017	0.432CysIle: 0.432 ± 0.018	0.282CysLys: 0.282 ± 0.014	1.078CysLeu: 1.078 ± 0.033	0.18CysMet: 0.18 ± 0.012	0.252CysAsn: 0.252 ± 0.014	0.594CysPro: 0.594 ± 0.023	0.405CysGln: 0.405 ± 0.015	0.727CysArg: 0.727 ± 0.027	0.508CysSer: 0.508 ± 0.019	0.495CysThr: 0.495 ± 0.021	0.621CysVal: 0.621 ± 0.022	0.151CysTrp: 0.151 ± 0.011	0.315CysTyr: 0.315 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	5.303AspAla: 5.303 ± 0.071	0.526AspCys: 0.526 ± 0.021	2.662AspAsp: 2.662 ± 0.058	3.066AspGlu: 3.066 ± 0.058	2.135AspPhe: 2.135 ± 0.045	4.026AspGly: 4.026 ± 0.065	1.211AspHis: 1.211 ± 0.039	2.691AspIle: 2.691 ± 0.047	1.642AspLys: 1.642 ± 0.041	6.083AspLeu: 6.083 ± 0.081	0.97AspMet: 0.97 ± 0.028	1.412AspAsn: 1.412 ± 0.038	3.411AspPro: 3.411 ± 0.05	2.182AspGln: 2.182 ± 0.047	3.702AspArg: 3.702 ± 0.059	2.676AspSer: 2.676 ± 0.044	2.609AspThr: 2.609 ± 0.051	3.212AspVal: 3.212 ± 0.058	1.049AspTrp: 1.049 ± 0.03	1.757AspTyr: 1.757 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	6.414GluAla: 6.414 ± 0.09	0.477GluCys: 0.477 ± 0.02	2.344GluAsp: 2.344 ± 0.05	3.147GluGlu: 3.147 ± 0.066	1.915GluPhe: 1.915 ± 0.038	3.53GluGly: 3.53 ± 0.06	1.401GluHis: 1.401 ± 0.036	3.526GluIle: 3.526 ± 0.062	2.21GluLys: 2.21 ± 0.055	6.252GluLeu: 6.252 ± 0.096	1.312GluMet: 1.312 ± 0.031	1.684GluAsn: 1.684 ± 0.041	2.929GluPro: 2.929 ± 0.056	3.186GluGln: 3.186 ± 0.055	5.438GluArg: 5.438 ± 0.074	2.765GluSer: 2.765 ± 0.053	3.339GluThr: 3.339 ± 0.054	3.724GluVal: 3.724 ± 0.065	0.833GluTrp: 0.833 ± 0.027	1.224GluTyr: 1.224 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	3.763PheAla: 3.763 ± 0.057	0.452PheCys: 0.452 ± 0.019	2.193PheAsp: 2.193 ± 0.046	1.967PheGlu: 1.967 ± 0.042	1.541PhePhe: 1.541 ± 0.039	3.106PheGly: 3.106 ± 0.048	0.793PheHis: 0.793 ± 0.028	1.819PheIle: 1.819 ± 0.043	1.164PheLys: 1.164 ± 0.033	3.813PheLeu: 3.813 ± 0.063	0.718PheMet: 0.718 ± 0.028	1.23PheAsn: 1.23 ± 0.033	1.59PhePro: 1.59 ± 0.038	1.386PheGln: 1.386 ± 0.035	2.175PheArg: 2.175 ± 0.042	2.26PheSer: 2.26 ± 0.049	1.939PheThr: 1.939 ± 0.05	2.308PheVal: 2.308 ± 0.049	0.596PheTrp: 0.596 ± 0.025	1.08PheTyr: 1.08 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	6.931GlyAla: 6.931 ± 0.087	0.956GlyCys: 0.956 ± 0.031	3.886GlyAsp: 3.886 ± 0.062	4.387GlyGlu: 4.387 ± 0.059	3.271GlyPhe: 3.271 ± 0.055	6.135GlyGly: 6.135 ± 0.1	1.805GlyHis: 1.805 ± 0.036	4.277GlyIle: 4.277 ± 0.067	3.072GlyLys: 3.072 ± 0.062	8.825GlyLeu: 8.825 ± 0.094	2.023GlyMet: 2.023 ± 0.084	2.059GlyAsn: 2.059 ± 0.05	2.986GlyPro: 2.986 ± 0.049	3.487GlyGln: 3.487 ± 0.056	5.255GlyArg: 5.255 ± 0.069	4.088GlySer: 4.088 ± 0.065	3.833GlyThr: 3.833 ± 0.074	5.589GlyVal: 5.589 ± 0.081	1.421GlyTrp: 1.421 ± 0.042	2.393GlyTyr: 2.393 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.164HisAla: 2.164 ± 0.043	0.325HisCys: 0.325 ± 0.018	1.17HisAsp: 1.17 ± 0.033	1.152HisGlu: 1.152 ± 0.033	0.963HisPhe: 0.963 ± 0.027	1.88HisGly: 1.88 ± 0.041	0.749HisHis: 0.749 ± 0.026	1.091HisIle: 1.091 ± 0.026	0.574HisLys: 0.574 ± 0.022	2.616HisLeu: 2.616 ± 0.049	0.391HisMet: 0.391 ± 0.021	0.632HisAsn: 0.632 ± 0.022	1.583HisPro: 1.583 ± 0.04	1.034HisGln: 1.034 ± 0.029	1.754HisArg: 1.754 ± 0.039	1.132HisSer: 1.132 ± 0.032	1.036HisThr: 1.036 ± 0.031	1.221HisVal: 1.221 ± 0.033	0.477HisTrp: 0.477 ± 0.021	0.816HisTyr: 0.816 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.131IleAla: 6.131 ± 0.068	0.508IleCys: 0.508 ± 0.021	3.019IleAsp: 3.019 ± 0.054	3.333IleGlu: 3.333 ± 0.05	1.619IlePhe: 1.619 ± 0.042	4.499IleGly: 4.499 ± 0.073	1.159IleHis: 1.159 ± 0.034	2.44IleIle: 2.44 ± 0.053	1.937IleLys: 1.937 ± 0.044	4.872IleLeu: 4.872 ± 0.07	0.887IleMet: 0.887 ± 0.028	1.729IleAsn: 1.729 ± 0.039	2.701IlePro: 2.701 ± 0.049	1.819IleGln: 1.819 ± 0.038	3.468IleArg: 3.468 ± 0.06	2.68IleSer: 2.68 ± 0.048	2.888IleThr: 2.888 ± 0.052	3.475IleVal: 3.475 ± 0.054	0.574IleTrp: 0.574 ± 0.023	1.288IleTyr: 1.288 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.699LysAla: 3.699 ± 0.065	0.171LysCys: 0.171 ± 0.011	1.604LysAsp: 1.604 ± 0.046	1.827LysGlu: 1.827 ± 0.049	0.947LysPhe: 0.947 ± 0.028	2.305LysGly: 2.305 ± 0.053	0.67LysHis: 0.67 ± 0.024	2.017LysIle: 2.017 ± 0.049	1.494LysLys: 1.494 ± 0.041	3.471LysLeu: 3.471 ± 0.053	0.749LysMet: 0.749 ± 0.026	1.108LysAsn: 1.108 ± 0.032	2.175LysPro: 2.175 ± 0.048	1.419LysGln: 1.419 ± 0.04	2.323LysArg: 2.323 ± 0.048	1.739LysSer: 1.739 ± 0.037	2.169LysThr: 2.169 ± 0.042	2.349LysVal: 2.349 ± 0.05	0.365LysTrp: 0.365 ± 0.018	0.75LysTyr: 0.75 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.498LeuAla: 14.498 ± 0.142	1.113LeuCys: 1.113 ± 0.031	6.312LeuAsp: 6.312 ± 0.08	6.645LeuGlu: 6.645 ± 0.087	3.957LeuPhe: 3.957 ± 0.063	8.404LeuGly: 8.404 ± 0.098	2.481LeuHis: 2.481 ± 0.045	5.689LeuIle: 5.689 ± 0.071	3.972LeuLys: 3.972 ± 0.066	13.315LeuLeu: 13.315 ± 0.152	2.23LeuMet: 2.23 ± 0.045	3.362LeuAsn: 3.362 ± 0.055	6.495LeuPro: 6.495 ± 0.086	4.175LeuGln: 4.175 ± 0.061	8.352LeuArg: 8.352 ± 0.103	6.236LeuSer: 6.236 ± 0.069	6.183LeuThr: 6.183 ± 0.084	7.48LeuVal: 7.48 ± 0.083	1.581LeuTrp: 1.581 ± 0.043	2.715LeuTyr: 2.715 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.657MetAla: 2.657 ± 0.053	0.132MetCys: 0.132 ± 0.011	1.011MetAsp: 1.011 ± 0.032	1.109MetGlu: 1.109 ± 0.03	0.557MetPhe: 0.557 ± 0.023	1.577MetGly: 1.577 ± 0.056	0.358MetHis: 0.358 ± 0.015	1.091MetIle: 1.091 ± 0.03	0.879MetLys: 0.879 ± 0.028	2.193MetLeu: 2.193 ± 0.048	0.501MetMet: 0.501 ± 0.022	0.807MetAsn: 0.807 ± 0.022	1.182MetPro: 1.182 ± 0.027	0.766MetGln: 0.766 ± 0.027	1.41MetArg: 1.41 ± 0.035	1.367MetSer: 1.367 ± 0.052	1.397MetThr: 1.397 ± 0.038	1.503MetVal: 1.503 ± 0.033	0.149MetTrp: 0.149 ± 0.011	0.326MetTyr: 0.326 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.056AsnAla: 3.056 ± 0.062	0.262AsnCys: 0.262 ± 0.014	1.499AsnAsp: 1.499 ± 0.038	1.452AsnGlu: 1.452 ± 0.038	1.046AsnPhe: 1.046 ± 0.031	2.28AsnGly: 2.28 ± 0.05	0.638AsnHis: 0.638 ± 0.023	1.438AsnIle: 1.438 ± 0.04	0.866AsnLys: 0.866 ± 0.03	3.256AsnLeu: 3.256 ± 0.057	0.553AsnMet: 0.553 ± 0.024	0.886AsnAsn: 0.886 ± 0.039	2.246AsnPro: 2.246 ± 0.047	1.247AsnGln: 1.247 ± 0.036	2.244AsnArg: 2.244 ± 0.048	1.403AsnSer: 1.403 ± 0.041	1.497AsnThr: 1.497 ± 0.042	1.773AsnVal: 1.773 ± 0.047	0.432AsnTrp: 0.432 ± 0.017	0.826AsnTyr: 0.826 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.151ProAla: 6.151 ± 0.093	0.458ProCys: 0.458 ± 0.018	3.569ProAsp: 3.569 ± 0.054	3.529ProGlu: 3.529 ± 0.058	1.858ProPhe: 1.858 ± 0.04	4.066ProGly: 4.066 ± 0.064	1.163ProHis: 1.163 ± 0.032	2.535ProIle: 2.535 ± 0.046	1.65ProLys: 1.65 ± 0.04	5.894ProLeu: 5.894 ± 0.075	1.12ProMet: 1.12 ± 0.034	1.555ProAsn: 1.555 ± 0.039	3.482ProPro: 3.482 ± 0.091	1.945ProGln: 1.945 ± 0.041	2.873ProArg: 2.873 ± 0.051	2.872ProSer: 2.872 ± 0.055	3.175ProThr: 3.175 ± 0.066	4.347ProVal: 4.347 ± 0.071	0.836ProTrp: 0.836 ± 0.033	1.348ProTyr: 1.348 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	5.288GlnAla: 5.288 ± 0.092	0.349GlnCys: 0.349 ± 0.019	1.749GlnAsp: 1.749 ± 0.041	2.174GlnGlu: 2.174 ± 0.05	1.293GlnPhe: 1.293 ± 0.034	2.877GlnGly: 2.877 ± 0.053	1.017GlnHis: 1.017 ± 0.031	2.282GlnIle: 2.282 ± 0.045	1.321GlnLys: 1.321 ± 0.039	4.297GlnLeu: 4.297 ± 0.065	0.878GlnMet: 0.878 ± 0.026	1.179GlnAsn: 1.179 ± 0.031	2.599GlnPro: 2.599 ± 0.048	2.271GlnGln: 2.271 ± 0.056	3.772GlnArg: 3.772 ± 0.062	2.04GlnSer: 2.04 ± 0.043	2.201GlnThr: 2.201 ± 0.047	2.959GlnVal: 2.959 ± 0.048	0.625GlnTrp: 0.625 ± 0.024	0.935GlnTyr: 0.935 ± 0.03	0.001GlnXaa: 0.001 ± 0.001
Arg	6.998ArgAla: 6.998 ± 0.097	0.747ArgCys: 0.747 ± 0.025	3.743ArgAsp: 3.743 ± 0.053	4.552ArgGlu: 4.552 ± 0.073	3.004ArgPhe: 3.004 ± 0.054	4.426ArgGly: 4.426 ± 0.061	1.924ArgHis: 1.924 ± 0.042	3.745ArgIle: 3.745 ± 0.049	2.196ArgLys: 2.196 ± 0.044	9.215ArgLeu: 9.215 ± 0.108	1.574ArgMet: 1.574 ± 0.039	1.946ArgAsn: 1.946 ± 0.039	3.556ArgPro: 3.556 ± 0.059	3.816ArgGln: 3.816 ± 0.065	5.629ArgArg: 5.629 ± 0.081	3.277ArgSer: 3.277 ± 0.055	3.11ArgThr: 3.11 ± 0.049	4.71ArgVal: 4.71 ± 0.061	1.29ArgTrp: 1.29 ± 0.032	2.431ArgTyr: 2.431 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	5.607SerAla: 5.607 ± 0.071	0.486SerCys: 0.486 ± 0.018	2.535SerAsp: 2.535 ± 0.047	2.817SerGlu: 2.817 ± 0.057	1.885SerPhe: 1.885 ± 0.037	4.925SerGly: 4.925 ± 0.072	1.195SerHis: 1.195 ± 0.033	2.39SerIle: 2.39 ± 0.049	1.548SerLys: 1.548 ± 0.04	5.753SerLeu: 5.753 ± 0.073	1.116SerMet: 1.116 ± 0.033	1.435SerAsn: 1.435 ± 0.044	2.902SerPro: 2.902 ± 0.062	2.006SerGln: 2.006 ± 0.043	3.493SerArg: 3.493 ± 0.062	2.894SerSer: 2.894 ± 0.057	2.765SerThr: 2.765 ± 0.048	3.532SerVal: 3.532 ± 0.055	0.76SerTrp: 0.76 ± 0.023	1.394SerTyr: 1.394 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	6.185ThrAla: 6.185 ± 0.085	0.438ThrCys: 0.438 ± 0.019	2.803ThrAsp: 2.803 ± 0.051	2.835ThrGlu: 2.835 ± 0.05	1.765ThrPhe: 1.765 ± 0.037	4.627ThrGly: 4.627 ± 0.068	1.209ThrHis: 1.209 ± 0.032	2.452ThrIle: 2.452 ± 0.06	1.377ThrLys: 1.377 ± 0.039	6.886ThrLeu: 6.886 ± 0.088	0.914ThrMet: 0.914 ± 0.03	1.282ThrAsn: 1.282 ± 0.041	3.637ThrPro: 3.637 ± 0.072	1.927ThrGln: 1.927 ± 0.037	3.205ThrArg: 3.205 ± 0.052	2.434ThrSer: 2.434 ± 0.051	2.947ThrThr: 2.947 ± 0.073	4.561ThrVal: 4.561 ± 0.082	0.657ThrTrp: 0.657 ± 0.024	1.196ThrTyr: 1.196 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	8.025ValAla: 8.025 ± 0.08	0.749ValCys: 0.749 ± 0.028	3.682ValAsp: 3.682 ± 0.056	4.166ValGlu: 4.166 ± 0.071	2.518ValPhe: 2.518 ± 0.049	5.229ValGly: 5.229 ± 0.07	1.299ValHis: 1.299 ± 0.036	3.778ValIle: 3.778 ± 0.057	2.306ValLys: 2.306 ± 0.049	8.019ValLeu: 8.019 ± 0.081	1.577ValMet: 1.577 ± 0.04	2.088ValAsn: 2.088 ± 0.046	3.268ValPro: 3.268 ± 0.055	2.292ValGln: 2.292 ± 0.036	4.782ValArg: 4.782 ± 0.067	3.782ValSer: 3.782 ± 0.054	3.83ValThr: 3.83 ± 0.075	5.433ValVal: 5.433 ± 0.085	0.956ValTrp: 0.956 ± 0.031	1.611ValTyr: 1.611 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.235TrpAla: 1.235 ± 0.033	0.138TrpCys: 0.138 ± 0.01	0.632TrpAsp: 0.632 ± 0.026	0.727TrpGlu: 0.727 ± 0.026	0.597TrpPhe: 0.597 ± 0.022	0.954TrpGly: 0.954 ± 0.03	0.362TrpHis: 0.362 ± 0.018	0.653TrpIle: 0.653 ± 0.022	0.444TrpLys: 0.444 ± 0.018	2.419TrpLeu: 2.419 ± 0.059	0.292TrpMet: 0.292 ± 0.014	0.458TrpAsn: 0.458 ± 0.018	0.826TrpPro: 0.826 ± 0.028	0.837TrpGln: 0.837 ± 0.029	1.384TrpArg: 1.384 ± 0.039	0.779TrpSer: 0.779 ± 0.025	0.653TrpThr: 0.653 ± 0.024	1.074TrpVal: 1.074 ± 0.039	0.287TrpTrp: 0.287 ± 0.016	0.406TrpTyr: 0.406 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.514TyrAla: 2.514 ± 0.045	0.34TyrCys: 0.34 ± 0.018	1.334TyrAsp: 1.334 ± 0.037	1.285TyrGlu: 1.285 ± 0.034	1.017TyrPhe: 1.017 ± 0.028	2.206TyrGly: 2.206 ± 0.041	0.673TyrHis: 0.673 ± 0.023	1.004TyrIle: 1.004 ± 0.029	0.683TyrLys: 0.683 ± 0.027	3.202TyrLeu: 3.202 ± 0.056	0.411TyrMet: 0.411 ± 0.016	0.74TyrAsn: 0.74 ± 0.025	1.513TyrPro: 1.513 ± 0.041	1.415TyrGln: 1.415 ± 0.037	2.364TyrArg: 2.364 ± 0.043	1.304TyrSer: 1.304 ± 0.032	1.319TyrThr: 1.319 ± 0.031	1.516TyrVal: 1.516 ± 0.036	0.468TyrTrp: 0.468 ± 0.022	0.81TyrTyr: 0.81 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4014 proteins (1230550 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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