Amino acid dipepetide frequency for Ctenophore-associated circular virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.855AlaAla: 1.855 ± 1.404
0.0AlaCys: 0.0 ± 0.0
3.711AlaAsp: 3.711 ± 2.211
0.0AlaGlu: 0.0 ± 0.0
1.855AlaPhe: 1.855 ± 1.404
0.0AlaGly: 0.0 ± 0.0
1.855AlaHis: 1.855 ± 1.404
5.566AlaIle: 5.566 ± 4.211
5.566AlaLys: 5.566 ± 0.808
3.711AlaLeu: 3.711 ± 2.211
0.0AlaMet: 0.0 ± 0.0
1.855AlaAsn: 1.855 ± 1.106
0.0AlaPro: 0.0 ± 0.0
7.421AlaGln: 7.421 ± 0.596
9.276AlaArg: 9.276 ± 0.51
3.711AlaSer: 3.711 ± 0.298
5.566AlaThr: 5.566 ± 4.211
3.711AlaVal: 3.711 ± 0.298
0.0AlaTrp: 0.0 ± 0.0
7.421AlaTyr: 7.421 ± 3.105
0.0AlaXaa: 0.0 ± 0.0
Cys
1.855CysAla: 1.855 ± 1.106
0.0CysCys: 0.0 ± 0.0
1.855CysAsp: 1.855 ± 1.404
0.0CysGlu: 0.0 ± 0.0
3.711CysPhe: 3.711 ± 0.298
0.0CysGly: 0.0 ± 0.0
1.855CysHis: 1.855 ± 1.106
1.855CysIle: 1.855 ± 1.404
1.855CysLys: 1.855 ± 1.106
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.855CysArg: 1.855 ± 1.404
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.855CysTyr: 1.855 ± 1.404
0.0CysXaa: 0.0 ± 0.0
Asp
3.711AspAla: 3.711 ± 0.298
0.0AspCys: 0.0 ± 0.0
1.855AspAsp: 1.855 ± 1.106
7.421AspGlu: 7.421 ± 1.913
3.711AspPhe: 3.711 ± 0.298
5.566AspGly: 5.566 ± 3.317
0.0AspHis: 0.0 ± 0.0
3.711AspIle: 3.711 ± 0.298
1.855AspLys: 1.855 ± 1.404
7.421AspLeu: 7.421 ± 0.596
1.855AspMet: 1.855 ± 1.106
0.0AspAsn: 0.0 ± 0.0
11.132AspPro: 11.132 ± 3.403
1.855AspGln: 1.855 ± 1.106
7.421AspArg: 7.421 ± 1.913
1.855AspSer: 1.855 ± 1.106
7.421AspThr: 7.421 ± 3.105
0.0AspVal: 0.0 ± 0.0
1.855AspTrp: 1.855 ± 1.106
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.855GluAla: 1.855 ± 1.106
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
1.855GluGlu: 1.855 ± 1.106
5.566GluPhe: 5.566 ± 3.317
1.855GluGly: 1.855 ± 1.106
0.0GluHis: 0.0 ± 0.0
1.855GluIle: 1.855 ± 1.106
1.855GluLys: 1.855 ± 1.106
5.566GluLeu: 5.566 ± 1.701
3.711GluMet: 3.711 ± 2.211
0.0GluAsn: 0.0 ± 0.0
3.711GluPro: 3.711 ± 0.298
1.855GluGln: 1.855 ± 1.106
1.855GluArg: 1.855 ± 1.404
5.566GluSer: 5.566 ± 0.808
3.711GluThr: 3.711 ± 2.211
1.855GluVal: 1.855 ± 1.106
1.855GluTrp: 1.855 ± 1.106
1.855GluTyr: 1.855 ± 1.106
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.855PheCys: 1.855 ± 1.404
3.711PheAsp: 3.711 ± 2.807
1.855PheGlu: 1.855 ± 1.106
3.711PhePhe: 3.711 ± 0.298
3.711PheGly: 3.711 ± 2.211
1.855PheHis: 1.855 ± 1.404
3.711PheIle: 3.711 ± 2.211
0.0PheLys: 0.0 ± 0.0
5.566PheLeu: 5.566 ± 3.317
1.855PheMet: 1.855 ± 1.404
0.0PheAsn: 0.0 ± 0.0
5.566PhePro: 5.566 ± 3.317
1.855PheGln: 1.855 ± 1.106
5.566PheArg: 5.566 ± 1.701
1.855PheSer: 1.855 ± 1.106
1.855PheThr: 1.855 ± 1.106
5.566PheVal: 5.566 ± 0.808
0.0PheTrp: 0.0 ± 0.0
1.855PheTyr: 1.855 ± 1.106
0.0PheXaa: 0.0 ± 0.0
Gly
3.711GlyAla: 3.711 ± 0.298
1.855GlyCys: 1.855 ± 1.106
7.421GlyAsp: 7.421 ± 1.913
3.711GlyGlu: 3.711 ± 0.298
1.855GlyPhe: 1.855 ± 1.106
1.855GlyGly: 1.855 ± 1.106
0.0GlyHis: 0.0 ± 0.0
3.711GlyIle: 3.711 ± 0.298
7.421GlyLys: 7.421 ± 4.422
0.0GlyLeu: 0.0 ± 0.0
1.855GlyMet: 1.855 ± 1.106
0.0GlyAsn: 0.0 ± 0.0
0.0GlyPro: 0.0 ± 0.0
1.855GlyGln: 1.855 ± 1.106
7.421GlyArg: 7.421 ± 3.105
3.711GlySer: 3.711 ± 0.298
9.276GlyThr: 9.276 ± 4.509
1.855GlyVal: 1.855 ± 1.106
1.855GlyTrp: 1.855 ± 1.404
1.855GlyTyr: 1.855 ± 1.404
0.0GlyXaa: 0.0 ± 0.0
His
1.855HisAla: 1.855 ± 1.404
1.855HisCys: 1.855 ± 1.404
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.855HisPhe: 1.855 ± 1.106
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.855HisIle: 1.855 ± 1.404
1.855HisLys: 1.855 ± 1.404
1.855HisLeu: 1.855 ± 1.106
0.0HisMet: 0.0 ± 0.0
7.421HisAsn: 7.421 ± 0.596
3.711HisPro: 3.711 ± 2.211
1.855HisGln: 1.855 ± 1.404
1.855HisArg: 1.855 ± 1.106
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.855HisVal: 1.855 ± 1.106
1.855HisTrp: 1.855 ± 1.106
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.566IleAla: 5.566 ± 0.808
1.855IleCys: 1.855 ± 1.404
5.566IleAsp: 5.566 ± 4.211
5.566IleGlu: 5.566 ± 0.808
1.855IlePhe: 1.855 ± 1.106
5.566IleGly: 5.566 ± 0.808
0.0IleHis: 0.0 ± 0.0
3.711IleIle: 3.711 ± 0.298
1.855IleLys: 1.855 ± 1.106
3.711IleLeu: 3.711 ± 0.298
1.855IleMet: 1.855 ± 0.882
5.566IleAsn: 5.566 ± 1.701
1.855IlePro: 1.855 ± 1.404
1.855IleGln: 1.855 ± 1.404
1.855IleArg: 1.855 ± 1.404
1.855IleSer: 1.855 ± 1.404
0.0IleThr: 0.0 ± 0.0
0.0IleVal: 0.0 ± 0.0
1.855IleTrp: 1.855 ± 1.404
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
5.566LysAsp: 5.566 ± 3.317
1.855LysGlu: 1.855 ± 1.106
3.711LysPhe: 3.711 ± 0.298
1.855LysGly: 1.855 ± 1.106
3.711LysHis: 3.711 ± 2.807
1.855LysIle: 1.855 ± 1.106
3.711LysLys: 3.711 ± 0.298
1.855LysLeu: 1.855 ± 1.106
3.711LysMet: 3.711 ± 2.211
0.0LysAsn: 0.0 ± 0.0
0.0LysPro: 0.0 ± 0.0
0.0LysGln: 0.0 ± 0.0
7.421LysArg: 7.421 ± 0.596
1.855LysSer: 1.855 ± 1.106
3.711LysThr: 3.711 ± 2.211
0.0LysVal: 0.0 ± 0.0
0.0LysTrp: 0.0 ± 0.0
3.711LysTyr: 3.711 ± 0.298
0.0LysXaa: 0.0 ± 0.0
Leu
7.421LeuAla: 7.421 ± 0.596
0.0LeuCys: 0.0 ± 0.0
3.711LeuAsp: 3.711 ± 2.211
3.711LeuGlu: 3.711 ± 2.211
3.711LeuPhe: 3.711 ± 2.211
3.711LeuGly: 3.711 ± 2.211
3.711LeuHis: 3.711 ± 2.211
1.855LeuIle: 1.855 ± 1.106
1.855LeuLys: 1.855 ± 1.106
1.855LeuLeu: 1.855 ± 1.106
1.855LeuMet: 1.855 ± 1.404
11.132LeuAsn: 11.132 ± 5.912
3.711LeuPro: 3.711 ± 2.211
3.711LeuGln: 3.711 ± 0.298
7.421LeuArg: 7.421 ± 3.105
1.855LeuSer: 1.855 ± 1.106
5.566LeuThr: 5.566 ± 1.701
0.0LeuVal: 0.0 ± 0.0
1.855LeuTrp: 1.855 ± 1.404
1.855LeuTyr: 1.855 ± 1.404
0.0LeuXaa: 0.0 ± 0.0
Met
1.855MetAla: 1.855 ± 1.106
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.855MetGlu: 1.855 ± 1.106
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
1.855MetHis: 1.855 ± 1.404
1.855MetIle: 1.855 ± 1.404
1.855MetLys: 1.855 ± 1.106
1.855MetLeu: 1.855 ± 1.106
0.0MetMet: 0.0 ± 0.0
1.855MetAsn: 1.855 ± 1.404
1.855MetPro: 1.855 ± 1.106
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
3.711MetSer: 3.711 ± 2.807
1.855MetThr: 1.855 ± 1.106
1.855MetVal: 1.855 ± 1.106
0.0MetTrp: 0.0 ± 0.0
1.855MetTyr: 1.855 ± 1.106
0.0MetXaa: 0.0 ± 0.0
Asn
3.711AsnAla: 3.711 ± 0.298
0.0AsnCys: 0.0 ± 0.0
3.711AsnAsp: 3.711 ± 0.298
1.855AsnGlu: 1.855 ± 1.106
1.855AsnPhe: 1.855 ± 1.404
7.421AsnGly: 7.421 ± 3.105
0.0AsnHis: 0.0 ± 0.0
1.855AsnIle: 1.855 ± 1.404
0.0AsnLys: 0.0 ± 0.0
11.132AsnLeu: 11.132 ± 3.403
0.0AsnMet: 0.0 ± 0.982
5.566AsnAsn: 5.566 ± 0.808
1.855AsnPro: 1.855 ± 1.404
1.855AsnGln: 1.855 ± 1.404
3.711AsnArg: 3.711 ± 0.298
5.566AsnSer: 5.566 ± 4.211
3.711AsnThr: 3.711 ± 0.298
5.566AsnVal: 5.566 ± 3.317
1.855AsnTrp: 1.855 ± 1.106
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.855ProAla: 1.855 ± 1.106
0.0ProCys: 0.0 ± 0.0
11.132ProAsp: 11.132 ± 4.124
1.855ProGlu: 1.855 ± 1.106
0.0ProPhe: 0.0 ± 0.0
0.0ProGly: 0.0 ± 0.0
1.855ProHis: 1.855 ± 1.106
1.855ProIle: 1.855 ± 1.106
5.566ProLys: 5.566 ± 0.808
5.566ProLeu: 5.566 ± 4.211
0.0ProMet: 0.0 ± 0.0
3.711ProAsn: 3.711 ± 0.298
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
3.711ProArg: 3.711 ± 0.298
5.566ProSer: 5.566 ± 1.701
1.855ProThr: 1.855 ± 1.404
3.711ProVal: 3.711 ± 2.211
0.0ProTrp: 0.0 ± 0.0
1.855ProTyr: 1.855 ± 1.106
0.0ProXaa: 0.0 ± 0.0
Gln
3.711GlnAla: 3.711 ± 0.298
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.855GlnGlu: 1.855 ± 1.106
1.855GlnPhe: 1.855 ± 1.106
7.421GlnGly: 7.421 ± 1.913
0.0GlnHis: 0.0 ± 0.0
5.566GlnIle: 5.566 ± 1.701
0.0GlnLys: 0.0 ± 0.0
0.0GlnLeu: 0.0 ± 0.0
1.855GlnMet: 1.855 ± 1.404
3.711GlnAsn: 3.711 ± 2.807
0.0GlnPro: 0.0 ± 0.0
5.566GlnGln: 5.566 ± 0.808
5.566GlnArg: 5.566 ± 0.808
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
0.0GlnVal: 0.0 ± 0.0
1.855GlnTrp: 1.855 ± 1.106
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.566ArgAla: 5.566 ± 4.211
3.711ArgCys: 3.711 ± 0.298
3.711ArgAsp: 3.711 ± 2.807
1.855ArgGlu: 1.855 ± 1.106
3.711ArgPhe: 3.711 ± 0.298
5.566ArgGly: 5.566 ± 4.211
5.566ArgHis: 5.566 ± 0.808
1.855ArgIle: 1.855 ± 1.404
0.0ArgLys: 0.0 ± 0.0
5.566ArgLeu: 5.566 ± 0.808
1.855ArgMet: 1.855 ± 1.106
7.421ArgAsn: 7.421 ± 5.614
3.711ArgPro: 3.711 ± 0.298
3.711ArgGln: 3.711 ± 0.298
11.132ArgArg: 11.132 ± 0.894
7.421ArgSer: 7.421 ± 1.913
5.566ArgThr: 5.566 ± 3.317
3.711ArgVal: 3.711 ± 0.298
1.855ArgTrp: 1.855 ± 1.106
9.276ArgTyr: 9.276 ± 0.51
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
3.711SerAsp: 3.711 ± 0.298
3.711SerGlu: 3.711 ± 2.211
0.0SerPhe: 0.0 ± 0.0
3.711SerGly: 3.711 ± 0.298
0.0SerHis: 0.0 ± 0.0
1.855SerIle: 1.855 ± 1.106
3.711SerLys: 3.711 ± 0.298
1.855SerLeu: 1.855 ± 1.404
0.0SerMet: 0.0 ± 0.0
9.276SerAsn: 9.276 ± 0.51
3.711SerPro: 3.711 ± 2.211
1.855SerGln: 1.855 ± 1.404
1.855SerArg: 1.855 ± 1.404
3.711SerSer: 3.711 ± 2.211
5.566SerThr: 5.566 ± 1.701
5.566SerVal: 5.566 ± 1.701
1.855SerTrp: 1.855 ± 1.106
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
12.987ThrAla: 12.987 ± 7.316
0.0ThrCys: 0.0 ± 0.0
5.566ThrAsp: 5.566 ± 1.701
3.711ThrGlu: 3.711 ± 0.298
0.0ThrPhe: 0.0 ± 0.0
5.566ThrGly: 5.566 ± 4.211
3.711ThrHis: 3.711 ± 2.211
3.711ThrIle: 3.711 ± 0.298
1.855ThrLys: 1.855 ± 1.106
3.711ThrLeu: 3.711 ± 0.298
0.0ThrMet: 0.0 ± 0.0
3.711ThrAsn: 3.711 ± 2.211
1.855ThrPro: 1.855 ± 1.106
0.0ThrGln: 0.0 ± 0.0
3.711ThrArg: 3.711 ± 0.298
0.0ThrSer: 0.0 ± 0.0
1.855ThrThr: 1.855 ± 1.404
3.711ThrVal: 3.711 ± 0.298
1.855ThrTrp: 1.855 ± 1.106
3.711ThrTyr: 3.711 ± 0.298
0.0ThrXaa: 0.0 ± 0.0
Val
1.855ValAla: 1.855 ± 1.106
0.0ValCys: 0.0 ± 0.0
5.566ValAsp: 5.566 ± 0.808
1.855ValGlu: 1.855 ± 1.404
7.421ValPhe: 7.421 ± 4.422
3.711ValGly: 3.711 ± 2.211
1.855ValHis: 1.855 ± 1.106
0.0ValIle: 0.0 ± 0.0
1.855ValLys: 1.855 ± 1.106
3.711ValLeu: 3.711 ± 0.298
0.0ValMet: 0.0 ± 0.0
1.855ValAsn: 1.855 ± 1.106
3.711ValPro: 3.711 ± 2.807
1.855ValGln: 1.855 ± 1.106
5.566ValArg: 5.566 ± 3.317
0.0ValSer: 0.0 ± 0.0
1.855ValThr: 1.855 ± 1.404
7.421ValVal: 7.421 ± 0.596
1.855ValTrp: 1.855 ± 1.404
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
3.711TrpCys: 3.711 ± 0.298
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
3.711TrpPhe: 3.711 ± 0.298
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.855TrpLys: 1.855 ± 1.404
1.855TrpLeu: 1.855 ± 1.106
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.855TrpGln: 1.855 ± 1.106
1.855TrpArg: 1.855 ± 1.404
3.711TrpSer: 3.711 ± 2.211
1.855TrpThr: 1.855 ± 1.106
3.711TrpVal: 3.711 ± 0.298
1.855TrpTrp: 1.855 ± 1.404
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.711TyrAla: 3.711 ± 0.298
1.855TyrCys: 1.855 ± 1.106
1.855TyrAsp: 1.855 ± 1.106
1.855TyrGlu: 1.855 ± 1.106
1.855TyrPhe: 1.855 ± 1.404
3.711TyrGly: 3.711 ± 2.807
1.855TyrHis: 1.855 ± 1.404
3.711TyrIle: 3.711 ± 2.807
0.0TyrLys: 0.0 ± 0.0
3.711TyrLeu: 3.711 ± 2.211
1.855TyrMet: 1.855 ± 1.404
0.0TyrAsn: 0.0 ± 0.0
3.711TyrPro: 3.711 ± 2.211
0.0TyrGln: 0.0 ± 0.0
3.711TyrArg: 3.711 ± 0.298
0.0TyrSer: 0.0 ± 0.0
0.0TyrThr: 0.0 ± 0.0
1.855TyrVal: 1.855 ± 1.106
1.855TyrTrp: 1.855 ± 1.404
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (540 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski