Amino acid dipepetide frequency for Wuhan pillworm virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.035AlaAla: 3.035 ± 1.82
1.517AlaCys: 1.517 ± 0.484
3.035AlaAsp: 3.035 ± 0.777
0.0AlaGlu: 0.0 ± 0.0
1.517AlaPhe: 1.517 ± 1.302
4.552AlaGly: 4.552 ± 1.966
0.759AlaHis: 0.759 ± 0.627
0.759AlaIle: 0.759 ± 0.651
3.035AlaLys: 3.035 ± 1.396
9.105AlaLeu: 9.105 ± 2.102
2.276AlaMet: 2.276 ± 0.862
2.276AlaAsn: 2.276 ± 0.162
0.759AlaPro: 0.759 ± 0.591
3.794AlaGln: 3.794 ± 1.32
2.276AlaArg: 2.276 ± 1.222
5.311AlaSer: 5.311 ± 1.886
3.035AlaThr: 3.035 ± 1.596
3.035AlaVal: 3.035 ± 0.968
2.276AlaTrp: 2.276 ± 0.162
3.035AlaTyr: 3.035 ± 1.725
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.517CysAsp: 1.517 ± 0.721
0.759CysGlu: 0.759 ± 0.627
0.759CysPhe: 0.759 ± 0.591
1.517CysGly: 1.517 ± 0.721
0.759CysHis: 0.759 ± 0.651
0.0CysIle: 0.0 ± 0.0
0.759CysLys: 0.759 ± 0.651
0.759CysLeu: 0.759 ± 0.627
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.759CysSer: 0.759 ± 0.651
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
2.276CysTrp: 2.276 ± 1.087
0.759CysTyr: 0.759 ± 0.591
0.0CysXaa: 0.0 ± 0.0
Asp
3.035AspAla: 3.035 ± 0.481
0.759AspCys: 0.759 ± 0.627
1.517AspAsp: 1.517 ± 0.662
2.276AspGlu: 2.276 ± 1.146
5.311AspPhe: 5.311 ± 1.55
4.552AspGly: 4.552 ± 0.934
0.0AspHis: 0.0 ± 0.0
3.794AspIle: 3.794 ± 0.861
3.794AspLys: 3.794 ± 1.764
3.794AspLeu: 3.794 ± 2.182
1.517AspMet: 1.517 ± 0.662
3.035AspAsn: 3.035 ± 0.481
5.311AspPro: 5.311 ± 0.932
3.035AspGln: 3.035 ± 0.777
1.517AspArg: 1.517 ± 1.254
6.829AspSer: 6.829 ± 1.997
2.276AspThr: 2.276 ± 0.983
2.276AspVal: 2.276 ± 0.862
0.759AspTrp: 0.759 ± 0.591
3.794AspTyr: 3.794 ± 1.065
0.0AspXaa: 0.0 ± 0.0
Glu
1.517GluAla: 1.517 ± 0.662
0.0GluCys: 0.0 ± 0.0
0.759GluAsp: 0.759 ± 0.591
1.517GluGlu: 1.517 ± 0.662
1.517GluPhe: 1.517 ± 1.254
4.552GluGly: 4.552 ± 0.702
1.517GluHis: 1.517 ± 0.484
1.517GluIle: 1.517 ± 0.662
0.759GluLys: 0.759 ± 0.651
4.552GluLeu: 4.552 ± 0.324
0.759GluMet: 0.759 ± 0.591
2.276GluAsn: 2.276 ± 0.162
3.035GluPro: 3.035 ± 0.777
1.517GluGln: 1.517 ± 0.662
3.035GluArg: 3.035 ± 0.777
1.517GluSer: 1.517 ± 1.181
0.759GluThr: 0.759 ± 0.651
1.517GluVal: 1.517 ± 0.662
1.517GluTrp: 1.517 ± 1.254
1.517GluTyr: 1.517 ± 0.721
0.0GluXaa: 0.0 ± 0.0
Phe
0.759PheAla: 0.759 ± 0.591
2.276PheCys: 2.276 ± 1.146
0.0PheAsp: 0.0 ± 0.0
1.517PheGlu: 1.517 ± 0.484
0.759PhePhe: 0.759 ± 0.591
4.552PheGly: 4.552 ± 0.324
1.517PheHis: 1.517 ± 0.662
5.311PheIle: 5.311 ± 2.244
0.759PheLys: 0.759 ± 0.591
4.552PheLeu: 4.552 ± 1.724
0.0PheMet: 0.0 ± 0.0
1.517PheAsn: 1.517 ± 1.302
0.759PhePro: 0.759 ± 0.591
1.517PheGln: 1.517 ± 0.484
2.276PheArg: 2.276 ± 1.184
1.517PheSer: 1.517 ± 0.662
0.0PheThr: 0.0 ± 0.0
1.517PheVal: 1.517 ± 0.721
1.517PheTrp: 1.517 ± 1.181
2.276PheTyr: 2.276 ± 1.146
0.0PheXaa: 0.0 ± 0.0
Gly
5.311GlyAla: 5.311 ± 0.743
0.0GlyCys: 0.0 ± 0.0
3.794GlyAsp: 3.794 ± 0.861
3.794GlyGlu: 3.794 ± 0.358
3.035GlyPhe: 3.035 ± 0.968
4.552GlyGly: 4.552 ± 2.162
0.759GlyHis: 0.759 ± 0.591
6.07GlyIle: 6.07 ± 1.106
2.276GlyLys: 2.276 ± 0.983
1.517GlyLeu: 1.517 ± 1.181
0.759GlyMet: 0.759 ± 1.075
2.276GlyAsn: 2.276 ± 1.184
3.035GlyPro: 3.035 ± 1.396
3.035GlyGln: 3.035 ± 0.481
6.829GlyArg: 6.829 ± 1.911
7.587GlySer: 7.587 ± 2.089
8.346GlyThr: 8.346 ± 3.704
4.552GlyVal: 4.552 ± 0.702
3.794GlyTrp: 3.794 ± 0.711
1.517GlyTyr: 1.517 ± 0.484
0.0GlyXaa: 0.0 ± 0.0
His
2.276HisAla: 2.276 ± 0.862
0.0HisCys: 0.0 ± 0.0
1.517HisAsp: 1.517 ± 1.181
0.759HisGlu: 0.759 ± 0.627
0.0HisPhe: 0.0 ± 0.0
2.276HisGly: 2.276 ± 0.162
0.759HisHis: 0.759 ± 0.627
0.759HisIle: 0.759 ± 0.591
0.759HisLys: 0.759 ± 0.627
4.552HisLeu: 4.552 ± 1.051
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.759HisPro: 0.759 ± 0.627
1.517HisGln: 1.517 ± 1.302
1.517HisArg: 1.517 ± 1.254
1.517HisSer: 1.517 ± 0.662
0.0HisThr: 0.0 ± 0.0
1.517HisVal: 1.517 ± 0.662
0.759HisTrp: 0.759 ± 0.651
2.276HisTyr: 2.276 ± 1.222
0.0HisXaa: 0.0 ± 0.0
Ile
3.035IleAla: 3.035 ± 0.481
0.759IleCys: 0.759 ± 0.627
5.311IleAsp: 5.311 ± 0.408
3.794IleGlu: 3.794 ± 0.861
3.794IlePhe: 3.794 ± 1.065
3.035IleGly: 3.035 ± 0.968
3.035IleHis: 3.035 ± 0.968
3.035IleIle: 3.035 ± 1.619
1.517IleLys: 1.517 ± 1.181
5.311IleLeu: 5.311 ± 1.569
0.759IleMet: 0.759 ± 0.627
3.035IleAsn: 3.035 ± 0.777
1.517IlePro: 1.517 ± 0.484
3.035IleGln: 3.035 ± 0.481
3.035IleArg: 3.035 ± 1.324
4.552IleSer: 4.552 ± 1.314
2.276IleThr: 2.276 ± 0.862
3.794IleVal: 3.794 ± 1.407
1.517IleTrp: 1.517 ± 1.254
2.276IleTyr: 2.276 ± 1.772
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
6.829LysAsp: 6.829 ± 0.911
1.517LysGlu: 1.517 ± 0.662
3.035LysPhe: 3.035 ± 0.481
3.035LysGly: 3.035 ± 0.777
2.276LysHis: 2.276 ± 1.146
3.794LysIle: 3.794 ± 0.358
3.035LysLys: 3.035 ± 0.481
4.552LysLeu: 4.552 ± 1.724
2.276LysMet: 2.276 ± 0.162
1.517LysAsn: 1.517 ± 0.484
5.311LysPro: 5.311 ± 1.247
1.517LysGln: 1.517 ± 1.181
2.276LysArg: 2.276 ± 1.087
5.311LysSer: 5.311 ± 1.55
1.517LysThr: 1.517 ± 0.662
4.552LysVal: 4.552 ± 0.934
0.759LysTrp: 0.759 ± 0.591
1.517LysTyr: 1.517 ± 0.721
0.0LysXaa: 0.0 ± 0.0
Leu
4.552LeuAla: 4.552 ± 2.757
0.759LeuCys: 0.759 ± 0.627
6.829LeuAsp: 6.829 ± 1.543
3.794LeuGlu: 3.794 ± 1.065
5.311LeuPhe: 5.311 ± 2.34
5.311LeuGly: 5.311 ± 0.408
3.794LeuHis: 3.794 ± 0.358
4.552LeuIle: 4.552 ± 1.051
7.587LeuLys: 7.587 ± 1.089
9.863LeuLeu: 9.863 ± 3.606
2.276LeuMet: 2.276 ± 0.162
4.552LeuAsn: 4.552 ± 2.942
0.759LeuPro: 0.759 ± 0.591
6.07LeuGln: 6.07 ± 0.273
2.276LeuArg: 2.276 ± 0.862
10.622LeuSer: 10.622 ± 1.486
3.035LeuThr: 3.035 ± 0.968
5.311LeuVal: 5.311 ± 2.597
1.517LeuTrp: 1.517 ± 0.662
3.794LeuTyr: 3.794 ± 1.857
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.759MetCys: 0.759 ± 0.591
1.517MetAsp: 1.517 ± 0.662
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.759MetHis: 0.759 ± 0.627
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.517MetLeu: 1.517 ± 0.662
0.0MetMet: 0.0 ± 0.0
0.759MetAsn: 0.759 ± 0.651
0.759MetPro: 0.759 ± 0.651
0.759MetGln: 0.759 ± 0.627
3.035MetArg: 3.035 ± 1.619
3.035MetSer: 3.035 ± 0.481
2.276MetThr: 2.276 ± 0.162
0.759MetVal: 0.759 ± 0.651
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.794AsnAla: 3.794 ± 1.32
0.759AsnCys: 0.759 ± 0.651
0.759AsnAsp: 0.759 ± 0.651
2.276AsnGlu: 2.276 ± 1.222
1.517AsnPhe: 1.517 ± 0.484
3.035AsnGly: 3.035 ± 0.777
0.0AsnHis: 0.0 ± 0.0
3.035AsnIle: 3.035 ± 0.968
0.759AsnLys: 0.759 ± 0.651
5.311AsnLeu: 5.311 ± 2.244
1.517AsnMet: 1.517 ± 0.662
2.276AsnAsn: 2.276 ± 1.222
1.517AsnPro: 1.517 ± 1.254
3.794AsnGln: 3.794 ± 1.32
0.759AsnArg: 0.759 ± 0.627
4.552AsnSer: 4.552 ± 0.324
1.517AsnThr: 1.517 ± 1.302
3.794AsnVal: 3.794 ± 0.358
1.517AsnTrp: 1.517 ± 0.662
1.517AsnTyr: 1.517 ± 0.662
0.0AsnXaa: 0.0 ± 0.0
Pro
5.311ProAla: 5.311 ± 1.58
0.0ProCys: 0.0 ± 0.0
1.517ProAsp: 1.517 ± 0.662
3.035ProGlu: 3.035 ± 1.725
0.759ProPhe: 0.759 ± 0.627
5.311ProGly: 5.311 ± 1.569
0.759ProHis: 0.759 ± 0.591
0.759ProIle: 0.759 ± 0.627
1.517ProLys: 1.517 ± 0.721
2.276ProLeu: 2.276 ± 0.983
0.759ProMet: 0.759 ± 0.478
1.517ProAsn: 1.517 ± 0.484
3.794ProPro: 3.794 ± 0.358
1.517ProGln: 1.517 ± 1.181
3.794ProArg: 3.794 ± 2.23
6.07ProSer: 6.07 ± 0.273
6.829ProThr: 6.829 ± 0.911
1.517ProVal: 1.517 ± 0.484
1.517ProTrp: 1.517 ± 0.662
1.517ProTyr: 1.517 ± 0.484
0.0ProXaa: 0.0 ± 0.0
Gln
4.552GlnAla: 4.552 ± 2.872
0.0GlnCys: 0.0 ± 0.0
2.276GlnAsp: 2.276 ± 0.862
1.517GlnGlu: 1.517 ± 1.254
0.0GlnPhe: 0.0 ± 0.0
3.035GlnGly: 3.035 ± 1.596
1.517GlnHis: 1.517 ± 0.721
3.035GlnIle: 3.035 ± 1.619
3.794GlnLys: 3.794 ± 2.182
6.07GlnLeu: 6.07 ± 1.555
0.0GlnMet: 0.0 ± 0.0
0.759GlnAsn: 0.759 ± 0.651
2.276GlnPro: 2.276 ± 0.162
2.276GlnGln: 2.276 ± 1.222
5.311GlnArg: 5.311 ± 0.408
7.587GlnSer: 7.587 ± 2.534
1.517GlnThr: 1.517 ± 0.484
3.794GlnVal: 3.794 ± 1.32
0.759GlnTrp: 0.759 ± 0.627
0.759GlnTyr: 0.759 ± 0.591
0.0GlnXaa: 0.0 ± 0.0
Arg
1.517ArgAla: 1.517 ± 0.484
0.0ArgCys: 0.0 ± 0.0
3.794ArgAsp: 3.794 ± 0.711
3.035ArgGlu: 3.035 ± 1.324
3.035ArgPhe: 3.035 ± 0.777
3.794ArgGly: 3.794 ± 2.23
1.517ArgHis: 1.517 ± 1.254
4.552ArgIle: 4.552 ± 1.452
2.276ArgLys: 2.276 ± 1.772
6.07ArgLeu: 6.07 ± 3.03
0.0ArgMet: 0.0 ± 0.0
6.829ArgAsn: 6.829 ± 0.543
0.0ArgPro: 0.0 ± 0.0
3.035ArgGln: 3.035 ± 0.679
5.311ArgArg: 5.311 ± 0.743
3.794ArgSer: 3.794 ± 0.861
3.035ArgThr: 3.035 ± 0.481
3.035ArgVal: 3.035 ± 0.777
2.276ArgTrp: 2.276 ± 0.162
1.517ArgTyr: 1.517 ± 0.662
0.0ArgXaa: 0.0 ± 0.0
Ser
6.829SerAla: 6.829 ± 3.125
0.0SerCys: 0.0 ± 0.0
6.07SerAsp: 6.07 ± 1.555
1.517SerGlu: 1.517 ± 1.302
0.0SerPhe: 0.0 ± 0.0
7.587SerGly: 7.587 ± 3.238
1.517SerHis: 1.517 ± 1.181
3.035SerIle: 3.035 ± 0.481
12.14SerLys: 12.14 ± 0.536
3.794SerLeu: 3.794 ± 1.857
0.759SerMet: 0.759 ± 0.591
3.794SerAsn: 3.794 ± 1.267
3.035SerPro: 3.035 ± 0.679
5.311SerGln: 5.311 ± 1.714
7.587SerArg: 7.587 ± 2.813
6.829SerSer: 6.829 ± 2.325
8.346SerThr: 8.346 ± 2.643
8.346SerVal: 8.346 ± 2.559
3.035SerTrp: 3.035 ± 1.82
3.794SerTyr: 3.794 ± 1.764
0.0SerXaa: 0.0 ± 0.0
Thr
3.794ThrAla: 3.794 ± 0.861
2.276ThrCys: 2.276 ± 1.952
2.276ThrAsp: 2.276 ± 0.162
2.276ThrGlu: 2.276 ± 1.772
2.276ThrPhe: 2.276 ± 0.983
4.552ThrGly: 4.552 ± 1.452
0.0ThrHis: 0.0 ± 0.0
4.552ThrIle: 4.552 ± 1.968
2.276ThrLys: 2.276 ± 0.983
6.07ThrLeu: 6.07 ± 2.459
0.759ThrMet: 0.759 ± 0.514
0.0ThrAsn: 0.0 ± 0.0
8.346ThrPro: 8.346 ± 2.304
3.794ThrGln: 3.794 ± 1.267
0.759ThrArg: 0.759 ± 0.591
4.552ThrSer: 4.552 ± 1.724
4.552ThrThr: 4.552 ± 1.452
3.035ThrVal: 3.035 ± 1.396
0.759ThrTrp: 0.759 ± 0.591
0.759ThrTyr: 0.759 ± 0.651
0.0ThrXaa: 0.0 ± 0.0
Val
4.552ValAla: 4.552 ± 0.934
0.759ValCys: 0.759 ± 0.591
5.311ValAsp: 5.311 ± 0.932
0.0ValGlu: 0.0 ± 0.0
0.759ValPhe: 0.759 ± 0.591
5.311ValGly: 5.311 ± 0.408
0.759ValHis: 0.759 ± 0.651
6.07ValIle: 6.07 ± 2.008
3.035ValLys: 3.035 ± 0.481
4.552ValLeu: 4.552 ± 0.324
0.0ValMet: 0.0 ± 0.0
2.276ValAsn: 2.276 ± 1.952
7.587ValPro: 7.587 ± 3.76
1.517ValGln: 1.517 ± 1.254
3.794ValArg: 3.794 ± 1.403
6.07ValSer: 6.07 ± 1.323
3.794ValThr: 3.794 ± 1.267
6.829ValVal: 6.829 ± 1.997
2.276ValTrp: 2.276 ± 0.162
0.759ValTyr: 0.759 ± 0.591
0.0ValXaa: 0.0 ± 0.0
Trp
0.759TrpAla: 0.759 ± 0.591
0.0TrpCys: 0.0 ± 0.0
2.276TrpAsp: 2.276 ± 1.087
2.276TrpGlu: 2.276 ± 0.862
0.759TrpPhe: 0.759 ± 0.591
0.759TrpGly: 0.759 ± 0.627
0.759TrpHis: 0.759 ± 0.627
2.276TrpIle: 2.276 ± 1.146
2.276TrpLys: 2.276 ± 0.162
3.035TrpLeu: 3.035 ± 0.777
0.759TrpMet: 0.759 ± 0.651
0.759TrpAsn: 0.759 ± 0.591
0.0TrpPro: 0.0 ± 0.0
3.035TrpGln: 3.035 ± 0.968
0.0TrpArg: 0.0 ± 0.0
2.276TrpSer: 2.276 ± 1.184
1.517TrpThr: 1.517 ± 1.181
4.552TrpVal: 4.552 ± 2.942
0.0TrpTrp: 0.0 ± 0.0
1.517TrpTyr: 1.517 ± 0.721
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.759TyrAla: 0.759 ± 0.627
0.0TyrCys: 0.0 ± 0.0
2.276TyrAsp: 2.276 ± 1.087
0.0TyrGlu: 0.0 ± 0.0
0.759TyrPhe: 0.759 ± 0.591
2.276TyrGly: 2.276 ± 1.087
0.759TyrHis: 0.759 ± 0.627
1.517TyrIle: 1.517 ± 0.662
2.276TyrLys: 2.276 ± 1.772
5.311TyrLeu: 5.311 ± 0.743
0.0TyrMet: 0.0 ± 0.0
4.552TyrAsn: 4.552 ± 0.934
1.517TyrPro: 1.517 ± 1.254
0.759TyrGln: 0.759 ± 0.627
3.035TyrArg: 3.035 ± 1.725
3.035TyrSer: 3.035 ± 0.679
3.035TyrThr: 3.035 ± 0.481
2.276TyrVal: 2.276 ± 1.222
0.759TyrTrp: 0.759 ± 0.627
1.517TyrTyr: 1.517 ± 0.484
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1319 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski