Amino acid dipepetide frequency for Beihai picorna-like virus 30

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.848AlaAla: 5.848 ± 1.271
0.78AlaCys: 0.78 ± 0.319
5.068AlaAsp: 5.068 ± 0.952
5.068AlaGlu: 5.068 ± 0.207
3.509AlaPhe: 3.509 ± 0.43
3.899AlaGly: 3.899 ± 0.102
1.949AlaHis: 1.949 ± 1.068
4.288AlaIle: 4.288 ± 0.112
7.018AlaLys: 7.018 ± 0.115
3.899AlaLeu: 3.899 ± 0.644
0.39AlaMet: 0.39 ± 0.532
3.119AlaAsn: 3.119 ± 2.02
4.288AlaPro: 4.288 ± 0.112
0.78AlaGln: 0.78 ± 0.427
5.458AlaArg: 5.458 ± 0.007
6.238AlaSer: 6.238 ± 0.312
6.238AlaThr: 6.238 ± 3.294
5.068AlaVal: 5.068 ± 0.207
1.559AlaTrp: 1.559 ± 0.637
1.17AlaTyr: 1.17 ± 0.105
0.0AlaXaa: 0.0 ± 0.0
Cys
1.559CysAla: 1.559 ± 0.637
0.0CysCys: 0.0 ± 0.0
1.17CysAsp: 1.17 ± 0.641
1.949CysGlu: 1.949 ± 1.068
0.78CysPhe: 0.78 ± 0.319
0.78CysGly: 0.78 ± 0.427
0.39CysHis: 0.39 ± 0.214
0.0CysIle: 0.0 ± 0.0
0.39CysLys: 0.39 ± 0.214
1.17CysLeu: 1.17 ± 0.105
0.39CysMet: 0.39 ± 0.214
0.39CysAsn: 0.39 ± 0.214
1.559CysPro: 1.559 ± 0.854
0.39CysGln: 0.39 ± 0.214
0.39CysArg: 0.39 ± 0.214
1.559CysSer: 1.559 ± 0.108
0.39CysThr: 0.39 ± 0.214
1.17CysVal: 1.17 ± 0.641
0.78CysTrp: 0.78 ± 0.319
0.39CysTyr: 0.39 ± 0.214
0.0CysXaa: 0.0 ± 0.0
Asp
4.288AspAla: 4.288 ± 0.112
1.949AspCys: 1.949 ± 0.322
5.068AspAsp: 5.068 ± 0.539
6.628AspGlu: 6.628 ± 0.098
5.068AspPhe: 5.068 ± 0.539
2.339AspGly: 2.339 ± 0.21
1.559AspHis: 1.559 ± 0.854
3.509AspIle: 3.509 ± 0.315
4.678AspLys: 4.678 ± 0.325
7.407AspLeu: 7.407 ± 1.074
2.339AspMet: 2.339 ± 0.535
1.949AspAsn: 1.949 ± 0.424
3.509AspPro: 3.509 ± 1.061
0.39AspGln: 0.39 ± 0.214
1.559AspArg: 1.559 ± 0.854
3.119AspSer: 3.119 ± 0.962
3.119AspThr: 3.119 ± 0.529
1.949AspVal: 1.949 ± 0.424
0.78AspTrp: 0.78 ± 0.319
2.729AspTyr: 2.729 ± 0.749
0.0AspXaa: 0.0 ± 0.0
Glu
3.899GluAla: 3.899 ± 0.644
0.78GluCys: 0.78 ± 0.427
5.068GluAsp: 5.068 ± 1.284
8.577GluGlu: 8.577 ± 3.206
4.678GluPhe: 4.678 ± 2.562
2.339GluGly: 2.339 ± 1.281
1.559GluHis: 1.559 ± 0.108
5.848GluIle: 5.848 ± 1.711
3.899GluLys: 3.899 ± 2.135
7.797GluLeu: 7.797 ± 0.949
3.509GluMet: 3.509 ± 2.287
1.17GluAsn: 1.17 ± 0.105
2.339GluPro: 2.339 ± 0.21
2.729GluGln: 2.729 ± 0.749
2.729GluArg: 2.729 ± 0.749
3.119GluSer: 3.119 ± 0.217
3.509GluThr: 3.509 ± 0.315
4.288GluVal: 4.288 ± 0.857
0.39GluTrp: 0.39 ± 0.214
2.339GluTyr: 2.339 ± 0.21
0.0GluXaa: 0.0 ± 0.0
Phe
5.068PheAla: 5.068 ± 0.952
1.949PheCys: 1.949 ± 1.068
4.288PheAsp: 4.288 ± 0.857
4.288PheGlu: 4.288 ± 0.857
3.509PhePhe: 3.509 ± 0.315
4.678PheGly: 4.678 ± 1.071
2.339PheHis: 2.339 ± 1.281
2.729PheIle: 2.729 ± 0.749
2.729PheLys: 2.729 ± 0.749
3.119PheLeu: 3.119 ± 0.962
1.559PheMet: 1.559 ± 0.108
1.949PheAsn: 1.949 ± 1.169
1.949PhePro: 1.949 ± 1.915
1.17PheGln: 1.17 ± 0.105
1.17PheArg: 1.17 ± 0.851
2.339PheSer: 2.339 ± 0.956
3.899PheThr: 3.899 ± 0.644
1.949PheVal: 1.949 ± 0.322
0.39PheTrp: 0.39 ± 0.214
2.729PheTyr: 2.729 ± 0.742
0.0PheXaa: 0.0 ± 0.0
Gly
4.288GlyAla: 4.288 ± 2.125
1.949GlyCys: 1.949 ± 1.068
2.339GlyAsp: 2.339 ± 0.21
2.729GlyGlu: 2.729 ± 0.003
5.458GlyPhe: 5.458 ± 1.498
3.119GlyGly: 3.119 ± 2.02
1.17GlyHis: 1.17 ± 0.105
3.899GlyIle: 3.899 ± 0.102
2.339GlyLys: 2.339 ± 0.21
2.339GlyLeu: 2.339 ± 0.21
1.17GlyMet: 1.17 ± 0.641
3.899GlyAsn: 3.899 ± 0.102
2.729GlyPro: 2.729 ± 0.742
3.509GlyGln: 3.509 ± 0.315
3.899GlyArg: 3.899 ± 0.847
5.848GlySer: 5.848 ± 2.017
3.119GlyThr: 3.119 ± 2.02
3.509GlyVal: 3.509 ± 0.43
1.17GlyTrp: 1.17 ± 0.851
3.119GlyTyr: 3.119 ± 2.02
0.0GlyXaa: 0.0 ± 0.0
His
3.509HisAla: 3.509 ± 1.806
0.39HisCys: 0.39 ± 0.214
0.78HisAsp: 0.78 ± 0.427
1.949HisGlu: 1.949 ± 0.424
1.559HisPhe: 1.559 ± 0.108
1.559HisGly: 1.559 ± 0.854
1.17HisHis: 1.17 ± 0.641
1.559HisIle: 1.559 ± 0.108
0.78HisLys: 0.78 ± 0.427
1.17HisLeu: 1.17 ± 0.641
1.17HisMet: 1.17 ± 0.641
0.78HisAsn: 0.78 ± 0.427
2.729HisPro: 2.729 ± 0.749
0.78HisGln: 0.78 ± 0.427
1.559HisArg: 1.559 ± 0.108
1.949HisSer: 1.949 ± 1.068
1.17HisThr: 1.17 ± 0.105
1.949HisVal: 1.949 ± 1.068
0.78HisTrp: 0.78 ± 0.319
3.119HisTyr: 3.119 ± 0.529
0.0HisXaa: 0.0 ± 0.0
Ile
3.899IleAla: 3.899 ± 0.644
0.0IleCys: 0.0 ± 0.0
3.509IleAsp: 3.509 ± 0.315
1.949IleGlu: 1.949 ± 1.068
3.509IlePhe: 3.509 ± 1.176
2.339IleGly: 2.339 ± 0.956
1.559IleHis: 1.559 ± 1.383
2.339IleIle: 2.339 ± 0.535
2.339IleLys: 2.339 ± 1.281
3.509IleLeu: 3.509 ± 0.43
1.949IleMet: 1.949 ± 0.322
3.119IleAsn: 3.119 ± 0.217
4.288IlePro: 4.288 ± 0.634
1.17IleGln: 1.17 ± 0.641
1.949IleArg: 1.949 ± 0.322
6.238IleSer: 6.238 ± 0.434
3.119IleThr: 3.119 ± 0.529
3.509IleVal: 3.509 ± 0.43
0.39IleTrp: 0.39 ± 0.214
1.17IleTyr: 1.17 ± 0.851
0.0IleXaa: 0.0 ± 0.0
Lys
4.288LysAla: 4.288 ± 1.603
0.39LysCys: 0.39 ± 0.214
5.848LysAsp: 5.848 ± 1.711
1.949LysGlu: 1.949 ± 1.068
2.729LysPhe: 2.729 ± 1.495
4.288LysGly: 4.288 ± 0.857
1.949LysHis: 1.949 ± 1.068
2.339LysIle: 2.339 ± 1.281
4.288LysLys: 4.288 ± 2.349
6.628LysLeu: 6.628 ± 0.844
1.17LysMet: 1.17 ± 0.105
1.949LysAsn: 1.949 ± 1.068
2.729LysPro: 2.729 ± 0.749
1.949LysGln: 1.949 ± 0.322
4.288LysArg: 4.288 ± 1.603
5.068LysSer: 5.068 ± 2.03
3.899LysThr: 3.899 ± 0.644
2.729LysVal: 2.729 ± 0.742
0.39LysTrp: 0.39 ± 0.532
1.949LysTyr: 1.949 ± 0.424
0.0LysXaa: 0.0 ± 0.0
Leu
5.458LeuAla: 5.458 ± 0.752
0.78LeuCys: 0.78 ± 0.427
3.509LeuAsp: 3.509 ± 1.061
5.848LeuGlu: 5.848 ± 1.711
2.339LeuPhe: 2.339 ± 0.21
5.848LeuGly: 5.848 ± 1.271
2.729LeuHis: 2.729 ± 0.749
3.509LeuIle: 3.509 ± 1.061
7.018LeuLys: 7.018 ± 1.606
3.509LeuLeu: 3.509 ± 1.176
1.17LeuMet: 1.17 ± 0.105
1.17LeuAsn: 1.17 ± 0.851
4.678LeuPro: 4.678 ± 0.325
2.339LeuGln: 2.339 ± 1.281
4.288LeuArg: 4.288 ± 0.634
5.458LeuSer: 5.458 ± 2.23
5.848LeuThr: 5.848 ± 1.271
5.068LeuVal: 5.068 ± 1.284
0.78LeuTrp: 0.78 ± 0.427
2.339LeuTyr: 2.339 ± 0.535
0.0LeuXaa: 0.0 ± 0.0
Met
1.17MetAla: 1.17 ± 0.641
0.39MetCys: 0.39 ± 0.214
2.339MetAsp: 2.339 ± 0.21
1.17MetGlu: 1.17 ± 0.105
1.17MetPhe: 1.17 ± 0.105
1.949MetGly: 1.949 ± 1.169
1.17MetHis: 1.17 ± 0.641
2.339MetIle: 2.339 ± 0.535
1.17MetLys: 1.17 ± 0.105
2.339MetLeu: 2.339 ± 0.21
0.78MetMet: 0.78 ± 0.319
2.339MetAsn: 2.339 ± 0.956
1.17MetPro: 1.17 ± 0.105
0.39MetGln: 0.39 ± 0.214
1.949MetArg: 1.949 ± 0.424
0.39MetSer: 0.39 ± 0.532
2.729MetThr: 2.729 ± 0.742
1.17MetVal: 1.17 ± 0.105
0.0MetTrp: 0.0 ± 0.0
0.39MetTyr: 0.39 ± 0.532
0.0MetXaa: 0.0 ± 0.0
Asn
2.339AsnAla: 2.339 ± 0.21
0.78AsnCys: 0.78 ± 0.427
2.339AsnAsp: 2.339 ± 0.21
1.559AsnGlu: 1.559 ± 0.108
1.559AsnPhe: 1.559 ± 0.108
2.339AsnGly: 2.339 ± 2.447
0.39AsnHis: 0.39 ± 0.532
1.559AsnIle: 1.559 ± 0.108
3.119AsnLys: 3.119 ± 0.217
3.119AsnLeu: 3.119 ± 1.274
1.559AsnMet: 1.559 ± 0.854
0.78AsnAsn: 0.78 ± 0.427
3.899AsnPro: 3.899 ± 1.593
2.339AsnGln: 2.339 ± 0.21
1.559AsnArg: 1.559 ± 0.637
2.729AsnSer: 2.729 ± 0.742
1.559AsnThr: 1.559 ± 1.383
3.899AsnVal: 3.899 ± 0.102
1.17AsnTrp: 1.17 ± 0.105
1.17AsnTyr: 1.17 ± 0.641
0.0AsnXaa: 0.0 ± 0.0
Pro
4.678ProAla: 4.678 ± 0.42
0.0ProCys: 0.0 ± 0.0
2.339ProAsp: 2.339 ± 1.281
4.288ProGlu: 4.288 ± 1.603
2.729ProPhe: 2.729 ± 0.742
3.119ProGly: 3.119 ± 0.529
3.119ProHis: 3.119 ± 1.274
1.559ProIle: 1.559 ± 0.108
2.339ProLys: 2.339 ± 1.281
6.628ProLeu: 6.628 ± 0.647
0.39ProMet: 0.39 ± 0.532
0.78ProAsn: 0.78 ± 0.427
4.288ProPro: 4.288 ± 0.857
2.339ProGln: 2.339 ± 0.21
3.119ProArg: 3.119 ± 0.217
3.899ProSer: 3.899 ± 0.644
4.678ProThr: 4.678 ± 1.166
3.509ProVal: 3.509 ± 1.176
1.17ProTrp: 1.17 ± 0.641
2.339ProTyr: 2.339 ± 2.447
0.0ProXaa: 0.0 ± 0.0
Gln
2.339GlnAla: 2.339 ± 0.21
0.0GlnCys: 0.0 ± 0.0
0.78GlnAsp: 0.78 ± 0.319
2.339GlnGlu: 2.339 ± 0.535
1.17GlnPhe: 1.17 ± 0.105
2.729GlnGly: 2.729 ± 0.742
0.39GlnHis: 0.39 ± 0.214
0.78GlnIle: 0.78 ± 0.319
2.339GlnLys: 2.339 ± 1.281
1.949GlnLeu: 1.949 ± 0.322
0.39GlnMet: 0.39 ± 0.447
1.559GlnAsn: 1.559 ± 0.854
1.949GlnPro: 1.949 ± 0.322
0.0GlnGln: 0.0 ± 0.0
2.339GlnArg: 2.339 ± 0.535
2.339GlnSer: 2.339 ± 0.535
1.17GlnThr: 1.17 ± 0.105
1.17GlnVal: 1.17 ± 0.105
0.39GlnTrp: 0.39 ± 0.214
0.39GlnTyr: 0.39 ± 0.214
0.0GlnXaa: 0.0 ± 0.0
Arg
2.339ArgAla: 2.339 ± 0.21
0.39ArgCys: 0.39 ± 0.214
3.119ArgAsp: 3.119 ± 0.217
2.339ArgGlu: 2.339 ± 0.956
3.899ArgPhe: 3.899 ± 2.339
3.119ArgGly: 3.119 ± 0.217
2.339ArgHis: 2.339 ± 0.535
3.899ArgIle: 3.899 ± 1.389
3.119ArgLys: 3.119 ± 1.708
4.288ArgLeu: 4.288 ± 0.634
0.78ArgMet: 0.78 ± 0.427
2.339ArgAsn: 2.339 ± 0.956
3.899ArgPro: 3.899 ± 1.389
1.559ArgGln: 1.559 ± 0.637
4.288ArgArg: 4.288 ± 1.603
1.559ArgSer: 1.559 ± 0.854
1.949ArgThr: 1.949 ± 0.424
2.339ArgVal: 2.339 ± 1.281
0.39ArgTrp: 0.39 ± 0.214
3.119ArgTyr: 3.119 ± 0.217
0.0ArgXaa: 0.0 ± 0.0
Ser
4.288SerAla: 4.288 ± 0.112
0.78SerCys: 0.78 ± 0.319
3.119SerAsp: 3.119 ± 0.962
4.678SerGlu: 4.678 ± 1.071
2.729SerPhe: 2.729 ± 0.742
5.848SerGly: 5.848 ± 2.017
1.949SerHis: 1.949 ± 0.322
2.729SerIle: 2.729 ± 1.488
3.899SerLys: 3.899 ± 0.102
4.288SerLeu: 4.288 ± 0.857
1.949SerMet: 1.949 ± 1.169
2.729SerAsn: 2.729 ± 0.749
3.899SerPro: 3.899 ± 1.389
1.559SerGln: 1.559 ± 0.637
3.899SerArg: 3.899 ± 0.847
2.339SerSer: 2.339 ± 0.535
4.678SerThr: 4.678 ± 1.071
5.458SerVal: 5.458 ± 1.485
0.78SerTrp: 0.78 ± 0.319
1.949SerTyr: 1.949 ± 1.915
0.0SerXaa: 0.0 ± 0.0
Thr
5.068ThrAla: 5.068 ± 3.189
1.949ThrCys: 1.949 ± 0.424
3.119ThrAsp: 3.119 ± 1.274
5.458ThrGlu: 5.458 ± 0.752
3.899ThrPhe: 3.899 ± 0.102
4.678ThrGly: 4.678 ± 1.912
1.559ThrHis: 1.559 ± 0.108
3.899ThrIle: 3.899 ± 0.102
2.729ThrLys: 2.729 ± 0.742
5.068ThrLeu: 5.068 ± 0.207
1.559ThrMet: 1.559 ± 1.383
3.119ThrAsn: 3.119 ± 0.529
1.949ThrPro: 1.949 ± 0.424
0.78ThrGln: 0.78 ± 0.319
0.78ThrArg: 0.78 ± 0.319
3.509ThrSer: 3.509 ± 1.061
5.458ThrThr: 5.458 ± 3.721
5.068ThrVal: 5.068 ± 0.952
0.39ThrTrp: 0.39 ± 0.214
2.339ThrTyr: 2.339 ± 0.21
0.0ThrXaa: 0.0 ± 0.0
Val
7.407ValAla: 7.407 ± 1.074
1.949ValCys: 1.949 ± 0.322
6.238ValAsp: 6.238 ± 0.312
3.899ValGlu: 3.899 ± 0.102
1.949ValPhe: 1.949 ± 0.424
2.729ValGly: 2.729 ± 0.003
1.17ValHis: 1.17 ± 0.641
3.899ValIle: 3.899 ± 0.644
3.119ValLys: 3.119 ± 1.708
2.729ValLeu: 2.729 ± 0.003
1.949ValMet: 1.949 ± 0.322
4.288ValAsn: 4.288 ± 2.125
3.899ValPro: 3.899 ± 0.644
1.17ValGln: 1.17 ± 0.641
3.509ValArg: 3.509 ± 1.922
4.678ValSer: 4.678 ± 1.912
2.339ValThr: 2.339 ± 0.21
5.068ValVal: 5.068 ± 1.698
0.39ValTrp: 0.39 ± 0.214
2.729ValTyr: 2.729 ± 0.003
0.0ValXaa: 0.0 ± 0.0
Trp
0.78TrpAla: 0.78 ± 1.064
0.0TrpCys: 0.0 ± 0.0
1.17TrpAsp: 1.17 ± 0.641
1.17TrpGlu: 1.17 ± 0.641
0.39TrpPhe: 0.39 ± 0.532
0.39TrpGly: 0.39 ± 0.532
1.17TrpHis: 1.17 ± 0.641
0.39TrpIle: 0.39 ± 0.214
0.78TrpLys: 0.78 ± 0.319
0.78TrpLeu: 0.78 ± 0.319
0.78TrpMet: 0.78 ± 1.064
0.78TrpAsn: 0.78 ± 0.319
0.39TrpPro: 0.39 ± 0.214
0.39TrpGln: 0.39 ± 0.214
1.559TrpArg: 1.559 ± 0.854
0.0TrpSer: 0.0 ± 0.0
0.39TrpThr: 0.39 ± 0.214
1.17TrpVal: 1.17 ± 0.105
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.119TyrAla: 3.119 ± 0.529
0.39TyrCys: 0.39 ± 0.214
2.729TyrAsp: 2.729 ± 0.003
2.729TyrGlu: 2.729 ± 0.003
1.17TyrPhe: 1.17 ± 0.105
3.509TyrGly: 3.509 ± 1.061
0.78TyrHis: 0.78 ± 1.064
0.78TyrIle: 0.78 ± 1.064
2.729TyrLys: 2.729 ± 1.495
1.949TyrLeu: 1.949 ± 0.424
1.17TyrMet: 1.17 ± 0.641
1.559TyrAsn: 1.559 ± 1.383
1.17TyrPro: 1.17 ± 0.641
1.17TyrGln: 1.17 ± 0.105
0.78TyrArg: 0.78 ± 0.319
1.17TyrSer: 1.17 ± 1.596
3.119TyrThr: 3.119 ± 2.766
5.068TyrVal: 5.068 ± 0.207
0.39TyrTrp: 0.39 ± 0.214
1.949TyrTyr: 1.949 ± 1.169
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2566 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski