Amino acid dipepetide frequency for Rousettus aegyptiacus polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.54AlaAla: 5.54 ± 1.842
0.0AlaCys: 0.0 ± 0.0
3.878AlaAsp: 3.878 ± 1.876
3.878AlaGlu: 3.878 ± 1.749
1.662AlaPhe: 1.662 ± 0.758
3.878AlaGly: 3.878 ± 1.31
0.0AlaHis: 0.0 ± 0.0
3.878AlaIle: 3.878 ± 1.407
2.216AlaLys: 2.216 ± 0.864
7.202AlaLeu: 7.202 ± 4.021
1.108AlaMet: 1.108 ± 0.756
2.77AlaAsn: 2.77 ± 0.736
5.54AlaPro: 5.54 ± 1.871
6.648AlaGln: 6.648 ± 2.082
6.094AlaArg: 6.094 ± 2.954
2.216AlaSer: 2.216 ± 0.572
4.432AlaThr: 4.432 ± 1.795
4.432AlaVal: 4.432 ± 0.748
0.554AlaTrp: 0.554 ± 0.386
1.108AlaTyr: 1.108 ± 0.643
0.0AlaXaa: 0.0 ± 0.0
Cys
0.554CysAla: 0.554 ± 0.386
0.0CysCys: 0.0 ± 0.0
1.108CysAsp: 1.108 ± 0.773
0.0CysGlu: 0.0 ± 0.0
2.216CysPhe: 2.216 ± 1.539
0.554CysGly: 0.554 ± 0.386
1.662CysHis: 1.662 ± 0.745
1.108CysIle: 1.108 ± 0.515
2.216CysLys: 2.216 ± 0.864
2.216CysLeu: 2.216 ± 2.352
0.0CysMet: 0.0 ± 0.0
1.662CysAsn: 1.662 ± 0.899
0.0CysPro: 0.0 ± 0.0
0.554CysGln: 0.554 ± 0.386
1.662CysArg: 1.662 ± 1.159
1.662CysSer: 1.662 ± 0.729
0.554CysThr: 0.554 ± 0.386
0.554CysVal: 0.554 ± 0.386
0.554CysTrp: 0.554 ± 0.524
1.108CysTyr: 1.108 ± 1.644
0.0CysXaa: 0.0 ± 0.0
Asp
2.77AspAla: 2.77 ± 1.635
0.554AspCys: 0.554 ± 0.386
1.662AspAsp: 1.662 ± 0.964
1.108AspGlu: 1.108 ± 0.54
5.54AspPhe: 5.54 ± 2.849
2.77AspGly: 2.77 ± 0.509
1.108AspHis: 1.108 ± 0.77
2.77AspIle: 2.77 ± 0.509
4.432AspLys: 4.432 ± 1.157
6.648AspLeu: 6.648 ± 1.298
1.108AspMet: 1.108 ± 0.515
0.554AspAsn: 0.554 ± 0.524
3.878AspPro: 3.878 ± 0.607
1.108AspGln: 1.108 ± 0.773
0.0AspArg: 0.0 ± 0.0
3.878AspSer: 3.878 ± 1.31
2.216AspThr: 2.216 ± 0.864
2.216AspVal: 2.216 ± 0.814
2.216AspTrp: 2.216 ± 1.75
1.662AspTyr: 1.662 ± 0.765
0.0AspXaa: 0.0 ± 0.0
Glu
7.756GluAla: 7.756 ± 3.193
3.878GluCys: 3.878 ± 1.65
6.648GluAsp: 6.648 ± 1.946
8.31GluGlu: 8.31 ± 1.183
0.554GluPhe: 0.554 ± 0.386
4.432GluGly: 4.432 ± 1.25
1.108GluHis: 1.108 ± 0.773
2.216GluIle: 2.216 ± 1.247
3.324GluLys: 3.324 ± 1.325
6.648GluLeu: 6.648 ± 0.81
0.0GluMet: 0.0 ± 0.0
4.432GluAsn: 4.432 ± 0.804
2.216GluPro: 2.216 ± 1.545
1.662GluGln: 1.662 ± 0.756
0.554GluArg: 0.554 ± 0.386
4.432GluSer: 4.432 ± 2.514
2.77GluThr: 2.77 ± 1.837
6.094GluVal: 6.094 ± 1.962
1.108GluTrp: 1.108 ± 0.77
1.662GluTyr: 1.662 ± 0.745
0.0GluXaa: 0.0 ± 0.0
Phe
3.324PheAla: 3.324 ± 0.7
2.77PheCys: 2.77 ± 1.628
2.77PheAsp: 2.77 ± 1.025
2.77PheGlu: 2.77 ± 1.102
1.662PhePhe: 1.662 ± 0.83
0.554PheGly: 0.554 ± 0.822
0.554PheHis: 0.554 ± 0.386
0.554PheIle: 0.554 ± 0.545
2.77PheLys: 2.77 ± 1.05
4.432PheLeu: 4.432 ± 1.896
1.108PheMet: 1.108 ± 0.77
1.108PheAsn: 1.108 ± 0.515
4.432PhePro: 4.432 ± 0.748
1.108PheGln: 1.108 ± 0.515
1.108PheArg: 1.108 ± 0.673
3.324PheSer: 3.324 ± 0.748
3.878PheThr: 3.878 ± 1.364
3.878PheVal: 3.878 ± 1.65
1.662PheTrp: 1.662 ± 1.116
0.554PheTyr: 0.554 ± 0.524
0.0PheXaa: 0.0 ± 0.0
Gly
6.648GlyAla: 6.648 ± 2.313
0.554GlyCys: 0.554 ± 0.386
3.878GlyAsp: 3.878 ± 0.607
4.432GlyGlu: 4.432 ± 1.903
2.77GlyPhe: 2.77 ± 1.68
6.648GlyGly: 6.648 ± 1.867
1.108GlyHis: 1.108 ± 0.756
2.77GlyIle: 2.77 ± 1.16
2.216GlyLys: 2.216 ± 1.069
7.202GlyLeu: 7.202 ± 2.13
1.662GlyMet: 1.662 ± 0.83
3.878GlyAsn: 3.878 ± 0.489
4.432GlyPro: 4.432 ± 0.456
2.77GlyGln: 2.77 ± 1.05
3.324GlyArg: 3.324 ± 2.649
3.324GlySer: 3.324 ± 1.403
3.878GlyThr: 3.878 ± 1.749
4.986GlyVal: 4.986 ± 1.448
0.0GlyTrp: 0.0 ± 0.0
1.662GlyTyr: 1.662 ± 0.83
0.0GlyXaa: 0.0 ± 0.0
His
1.662HisAla: 1.662 ± 0.833
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.108HisGlu: 1.108 ± 0.773
2.216HisPhe: 2.216 ± 0.888
1.108HisGly: 1.108 ± 0.643
2.216HisHis: 2.216 ± 1.346
0.0HisIle: 0.0 ± 0.0
4.432HisLys: 4.432 ± 1.496
3.324HisLeu: 3.324 ± 1.285
0.0HisMet: 0.0 ± 0.0
0.554HisAsn: 0.554 ± 0.524
2.216HisPro: 2.216 ± 1.052
1.108HisGln: 1.108 ± 1.159
2.216HisArg: 2.216 ± 1.657
1.108HisSer: 1.108 ± 0.515
1.108HisThr: 1.108 ± 0.883
1.662HisVal: 1.662 ± 0.833
0.0HisTrp: 0.0 ± 0.0
0.554HisTyr: 0.554 ± 0.386
0.0HisXaa: 0.0 ± 0.0
Ile
2.77IleAla: 2.77 ± 0.936
1.108IleCys: 1.108 ± 0.773
1.662IleAsp: 1.662 ± 0.756
2.77IleGlu: 2.77 ± 1.472
2.216IlePhe: 2.216 ± 1.346
2.216IleGly: 2.216 ± 1.759
1.108IleHis: 1.108 ± 0.515
2.77IleIle: 2.77 ± 1.221
0.554IleLys: 0.554 ± 0.386
5.54IleLeu: 5.54 ± 1.136
0.0IleMet: 0.0 ± 0.0
1.662IleAsn: 1.662 ± 1.165
1.108IlePro: 1.108 ± 0.773
1.662IleGln: 1.662 ± 0.964
1.662IleArg: 1.662 ± 0.833
2.77IleSer: 2.77 ± 0.645
3.324IleThr: 3.324 ± 1.49
1.662IleVal: 1.662 ± 1.317
0.0IleTrp: 0.0 ± 0.0
3.324IleTyr: 3.324 ± 1.318
0.0IleXaa: 0.0 ± 0.0
Lys
5.54LysAla: 5.54 ± 2.099
2.216LysCys: 2.216 ± 1.539
1.662LysAsp: 1.662 ± 1.545
4.432LysGlu: 4.432 ± 2.514
0.554LysPhe: 0.554 ± 0.386
4.986LysGly: 4.986 ± 1.978
2.216LysHis: 2.216 ± 1.149
1.662LysIle: 1.662 ± 0.932
8.864LysLys: 8.864 ± 2.021
7.202LysLeu: 7.202 ± 2.402
1.662LysMet: 1.662 ± 0.964
1.662LysAsn: 1.662 ± 0.964
1.662LysPro: 1.662 ± 1.116
1.108LysGln: 1.108 ± 0.673
4.986LysArg: 4.986 ± 1.219
4.986LysSer: 4.986 ± 0.588
3.324LysThr: 3.324 ± 1.483
1.108LysVal: 1.108 ± 0.883
0.554LysTrp: 0.554 ± 0.386
2.216LysTyr: 2.216 ± 1.069
0.0LysXaa: 0.0 ± 0.0
Leu
6.648LeuAla: 6.648 ± 3.549
2.216LeuCys: 2.216 ± 1.069
3.878LeuAsp: 3.878 ± 1.388
6.648LeuGlu: 6.648 ± 1.844
4.986LeuPhe: 4.986 ± 1.612
5.54LeuGly: 5.54 ± 0.737
4.986LeuHis: 4.986 ± 1.911
5.54LeuIle: 5.54 ± 0.737
3.878LeuLys: 3.878 ± 1.273
11.08LeuLeu: 11.08 ± 2.956
3.324LeuMet: 3.324 ± 1.312
8.31LeuAsn: 8.31 ± 1.619
7.756LeuPro: 7.756 ± 2.196
7.756LeuGln: 7.756 ± 0.588
2.216LeuArg: 2.216 ± 0.572
4.986LeuSer: 4.986 ± 1.953
4.986LeuThr: 4.986 ± 1.439
3.878LeuVal: 3.878 ± 2.059
0.554LeuTrp: 0.554 ± 0.822
4.986LeuTyr: 4.986 ± 1.405
0.0LeuXaa: 0.0 ± 0.0
Met
2.216MetAla: 2.216 ± 0.87
0.554MetCys: 0.554 ± 0.386
1.662MetAsp: 1.662 ± 0.899
1.662MetGlu: 1.662 ± 0.899
0.554MetPhe: 0.554 ± 0.524
2.77MetGly: 2.77 ± 0.83
0.0MetHis: 0.0 ± 0.0
1.108MetIle: 1.108 ± 0.515
1.662MetLys: 1.662 ± 0.729
1.662MetLeu: 1.662 ± 0.833
0.0MetMet: 0.0 ± 0.0
1.108MetAsn: 1.108 ± 0.756
0.0MetPro: 0.0 ± 0.0
1.108MetGln: 1.108 ± 0.764
1.662MetArg: 1.662 ± 0.83
0.0MetSer: 0.0 ± 0.0
1.662MetThr: 1.662 ± 0.729
0.554MetVal: 0.554 ± 0.386
0.554MetTrp: 0.554 ± 0.524
0.554MetTyr: 0.554 ± 0.822
0.0MetXaa: 0.0 ± 0.0
Asn
2.216AsnAla: 2.216 ± 0.814
0.554AsnCys: 0.554 ± 0.524
1.108AsnAsp: 1.108 ± 0.773
2.216AsnGlu: 2.216 ± 1.464
1.108AsnPhe: 1.108 ± 0.77
4.432AsnGly: 4.432 ± 1.996
1.108AsnHis: 1.108 ± 1.019
2.216AsnIle: 2.216 ± 0.888
2.216AsnLys: 2.216 ± 1.069
5.54AsnLeu: 5.54 ± 1.565
2.216AsnMet: 2.216 ± 0.86
0.554AsnAsn: 0.554 ± 0.386
2.77AsnPro: 2.77 ± 1.261
1.662AsnGln: 1.662 ± 0.765
0.0AsnArg: 0.0 ± 0.0
0.554AsnSer: 0.554 ± 0.524
2.216AsnThr: 2.216 ± 1.03
3.878AsnVal: 3.878 ± 1.646
3.324AsnTrp: 3.324 ± 1.605
3.324AsnTyr: 3.324 ± 1.218
0.0AsnXaa: 0.0 ± 0.0
Pro
1.662ProAla: 1.662 ± 0.833
0.0ProCys: 0.0 ± 0.0
5.54ProAsp: 5.54 ± 1.173
7.202ProGlu: 7.202 ± 2.794
2.216ProPhe: 2.216 ± 0.814
5.54ProGly: 5.54 ± 1.095
0.554ProHis: 0.554 ± 0.524
1.662ProIle: 1.662 ± 1.038
4.986ProLys: 4.986 ± 1.57
4.986ProLeu: 4.986 ± 1.252
0.554ProMet: 0.554 ± 0.524
0.0ProAsn: 0.0 ± 0.0
7.756ProPro: 7.756 ± 1.707
1.662ProGln: 1.662 ± 0.756
2.77ProArg: 2.77 ± 0.794
6.094ProSer: 6.094 ± 1.478
2.216ProThr: 2.216 ± 0.621
3.324ProVal: 3.324 ± 1.545
0.0ProTrp: 0.0 ± 0.0
1.662ProTyr: 1.662 ± 0.954
0.0ProXaa: 0.0 ± 0.0
Gln
1.662GlnAla: 1.662 ± 0.765
0.0GlnCys: 0.0 ± 0.0
0.554GlnAsp: 0.554 ± 0.386
2.216GlnGlu: 2.216 ± 0.814
2.216GlnPhe: 2.216 ± 1.03
1.662GlnGly: 1.662 ± 0.964
1.662GlnHis: 1.662 ± 0.691
2.216GlnIle: 2.216 ± 0.572
3.324GlnLys: 3.324 ± 1.977
4.432GlnLeu: 4.432 ± 1.426
1.108GlnMet: 1.108 ± 0.756
1.662GlnAsn: 1.662 ± 0.729
2.216GlnPro: 2.216 ± 0.572
2.77GlnGln: 2.77 ± 0.509
4.432GlnArg: 4.432 ± 2.339
2.77GlnSer: 2.77 ± 0.969
3.324GlnThr: 3.324 ± 1.506
2.77GlnVal: 2.77 ± 1.472
0.554GlnTrp: 0.554 ± 0.386
2.216GlnTyr: 2.216 ± 1.766
0.0GlnXaa: 0.0 ± 0.0
Arg
2.77ArgAla: 2.77 ± 1.635
0.554ArgCys: 0.554 ± 0.386
1.662ArgAsp: 1.662 ± 0.899
3.324ArgGlu: 3.324 ± 1.605
1.662ArgPhe: 1.662 ± 0.756
1.662ArgGly: 1.662 ± 0.833
4.432ArgHis: 4.432 ± 1.794
2.216ArgIle: 2.216 ± 1.069
4.986ArgLys: 4.986 ± 0.635
2.77ArgLeu: 2.77 ± 1.598
0.554ArgMet: 0.554 ± 0.524
1.108ArgAsn: 1.108 ± 0.673
1.108ArgPro: 1.108 ± 0.883
1.662ArgGln: 1.662 ± 1.059
2.216ArgArg: 2.216 ± 1.461
2.77ArgSer: 2.77 ± 0.509
2.77ArgThr: 2.77 ± 1.635
2.216ArgVal: 2.216 ± 1.069
1.108ArgTrp: 1.108 ± 0.883
6.648ArgTyr: 6.648 ± 2.065
0.0ArgXaa: 0.0 ± 0.0
Ser
5.54SerAla: 5.54 ± 0.975
1.108SerCys: 1.108 ± 0.77
3.324SerAsp: 3.324 ± 1.545
4.986SerGlu: 4.986 ± 2.219
4.986SerPhe: 4.986 ± 1.185
2.77SerGly: 2.77 ± 0.509
0.554SerHis: 0.554 ± 0.524
3.324SerIle: 3.324 ± 0.808
2.216SerLys: 2.216 ± 0.864
4.986SerLeu: 4.986 ± 1.592
2.77SerMet: 2.77 ± 0.651
4.432SerAsn: 4.432 ± 1.181
3.324SerPro: 3.324 ± 1.469
4.432SerGln: 4.432 ± 1.021
3.324SerArg: 3.324 ± 1.318
3.878SerSer: 3.878 ± 1.234
4.432SerThr: 4.432 ± 1.744
1.108SerVal: 1.108 ± 0.515
2.216SerTrp: 2.216 ± 1.13
2.216SerTyr: 2.216 ± 1.57
0.0SerXaa: 0.0 ± 0.0
Thr
2.216ThrAla: 2.216 ± 0.572
1.662ThrCys: 1.662 ± 0.729
2.216ThrAsp: 2.216 ± 0.572
4.986ThrGlu: 4.986 ± 1.503
1.662ThrPhe: 1.662 ± 0.691
6.094ThrGly: 6.094 ± 1.251
0.0ThrHis: 0.0 ± 0.0
1.108ThrIle: 1.108 ± 1.047
0.554ThrLys: 0.554 ± 0.386
10.526ThrLeu: 10.526 ± 0.581
0.554ThrMet: 0.554 ± 0.524
2.216ThrAsn: 2.216 ± 0.717
4.432ThrPro: 4.432 ± 0.748
1.662ThrGln: 1.662 ± 0.745
4.432ThrArg: 4.432 ± 1.819
4.986ThrSer: 4.986 ± 1.446
3.324ThrThr: 3.324 ± 1.196
3.878ThrVal: 3.878 ± 1.31
0.0ThrTrp: 0.0 ± 0.0
1.108ThrTyr: 1.108 ± 0.883
0.0ThrXaa: 0.0 ± 0.0
Val
2.216ValAla: 2.216 ± 0.91
0.0ValCys: 0.0 ± 0.0
3.324ValAsp: 3.324 ± 1.955
2.77ValGlu: 2.77 ± 1.454
1.108ValPhe: 1.108 ± 0.54
3.878ValGly: 3.878 ± 2.447
0.554ValHis: 0.554 ± 0.545
1.662ValIle: 1.662 ± 0.745
2.77ValLys: 2.77 ± 1.454
5.54ValLeu: 5.54 ± 1.365
0.554ValMet: 0.554 ± 0.386
4.432ValAsn: 4.432 ± 2.002
2.216ValPro: 2.216 ± 1.464
1.662ValGln: 1.662 ± 1.159
2.216ValArg: 2.216 ± 1.075
7.756ValSer: 7.756 ± 1.553
6.094ValThr: 6.094 ± 1.678
0.554ValVal: 0.554 ± 0.524
1.108ValTrp: 1.108 ± 0.883
1.662ValTyr: 1.662 ± 0.833
0.0ValXaa: 0.0 ± 0.0
Trp
2.77TrpAla: 2.77 ± 1.598
0.0TrpCys: 0.0 ± 0.0
1.108TrpAsp: 1.108 ± 0.54
3.878TrpGlu: 3.878 ± 2.492
0.554TrpPhe: 0.554 ± 0.822
1.662TrpGly: 1.662 ± 1.545
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.662TrpLys: 1.662 ± 0.899
0.0TrpLeu: 0.0 ± 0.0
1.662TrpMet: 1.662 ± 0.756
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.108TrpGln: 1.108 ± 0.883
0.554TrpArg: 0.554 ± 0.822
0.554TrpSer: 0.554 ± 0.822
0.0TrpThr: 0.0 ± 0.0
0.554TrpVal: 0.554 ± 0.524
0.554TrpTrp: 0.554 ± 0.386
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.554TyrAla: 0.554 ± 0.545
2.216TyrCys: 2.216 ± 1.539
0.554TyrAsp: 0.554 ± 0.386
1.108TyrGlu: 1.108 ± 0.773
3.878TyrPhe: 3.878 ± 2.492
4.986TyrGly: 4.986 ± 1.03
1.662TyrHis: 1.662 ± 0.833
1.108TyrIle: 1.108 ± 0.883
3.324TyrLys: 3.324 ± 2.309
2.77TyrLeu: 2.77 ± 1.05
0.554TyrMet: 0.554 ± 0.386
1.108TyrAsn: 1.108 ± 0.77
3.324TyrPro: 3.324 ± 1.218
0.554TyrGln: 0.554 ± 0.524
2.77TyrArg: 2.77 ± 1.454
3.878TyrSer: 3.878 ± 1.97
1.108TyrThr: 1.108 ± 0.515
2.77TyrVal: 2.77 ± 1.102
0.0TyrTrp: 0.0 ± 0.0
2.216TyrTyr: 2.216 ± 0.572
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1806 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski