Amino acid dipepetide frequency for Cryomyces minteri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.81AlaAla: 10.81 ± 0.07	0.933AlaCys: 0.933 ± 0.014	4.824AlaAsp: 4.824 ± 0.029	5.817AlaGlu: 5.817 ± 0.035	3.172AlaPhe: 3.172 ± 0.024	6.523AlaGly: 6.523 ± 0.04	2.0AlaHis: 2.0 ± 0.02	4.061AlaIle: 4.061 ± 0.028	4.47AlaLys: 4.47 ± 0.037	8.382AlaLeu: 8.382 ± 0.047	2.021AlaMet: 2.021 ± 0.02	3.106AlaAsn: 3.106 ± 0.021	5.265AlaPro: 5.265 ± 0.041	3.723AlaGln: 3.723 ± 0.027	5.6AlaArg: 5.6 ± 0.033	7.916AlaSer: 7.916 ± 0.049	5.83AlaThr: 5.83 ± 0.04	5.859AlaVal: 5.859 ± 0.035	1.145AlaTrp: 1.145 ± 0.015	2.284AlaTyr: 2.284 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.857CysAla: 0.857 ± 0.012	0.183CysCys: 0.183 ± 0.006	0.528CysAsp: 0.528 ± 0.012	0.523CysGlu: 0.523 ± 0.01	0.442CysPhe: 0.442 ± 0.008	0.815CysGly: 0.815 ± 0.014	0.271CysHis: 0.271 ± 0.007	0.551CysIle: 0.551 ± 0.01	0.446CysLys: 0.446 ± 0.009	1.039CysLeu: 1.039 ± 0.015	0.226CysMet: 0.226 ± 0.006	0.345CysAsn: 0.345 ± 0.008	0.535CysPro: 0.535 ± 0.01	0.358CysGln: 0.358 ± 0.007	0.605CysArg: 0.605 ± 0.011	0.692CysSer: 0.692 ± 0.013	0.612CysThr: 0.612 ± 0.01	0.725CysVal: 0.725 ± 0.011	0.154CysTrp: 0.154 ± 0.005	0.291CysTyr: 0.291 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.252AspAla: 5.252 ± 0.031	0.549AspCys: 0.549 ± 0.009	4.248AspAsp: 4.248 ± 0.039	4.768AspGlu: 4.768 ± 0.033	2.194AspPhe: 2.194 ± 0.022	4.337AspGly: 4.337 ± 0.028	1.22AspHis: 1.22 ± 0.014	2.748AspIle: 2.748 ± 0.025	2.327AspLys: 2.327 ± 0.023	5.032AspLeu: 5.032 ± 0.032	1.236AspMet: 1.236 ± 0.015	1.773AspAsn: 1.773 ± 0.018	3.265AspPro: 3.265 ± 0.025	1.819AspGln: 1.819 ± 0.019	3.209AspArg: 3.209 ± 0.029	3.96AspSer: 3.96 ± 0.026	3.052AspThr: 3.052 ± 0.025	4.069AspVal: 4.069 ± 0.029	0.852AspTrp: 0.852 ± 0.012	1.583AspTyr: 1.583 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.997GluAla: 5.997 ± 0.041	0.541GluCys: 0.541 ± 0.01	4.579GluAsp: 4.579 ± 0.04	6.022GluGlu: 6.022 ± 0.054	1.798GluPhe: 1.798 ± 0.019	4.214GluGly: 4.214 ± 0.031	1.485GluHis: 1.485 ± 0.017	2.849GluIle: 2.849 ± 0.024	3.753GluLys: 3.753 ± 0.031	5.335GluLeu: 5.335 ± 0.043	1.485GluMet: 1.485 ± 0.015	2.046GluAsn: 2.046 ± 0.019	2.681GluPro: 2.681 ± 0.022	2.682GluGln: 2.682 ± 0.027	4.447GluArg: 4.447 ± 0.035	3.978GluSer: 3.978 ± 0.028	3.367GluThr: 3.367 ± 0.025	3.816GluVal: 3.816 ± 0.03	0.871GluTrp: 0.871 ± 0.011	1.629GluTyr: 1.629 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.178PheAla: 3.178 ± 0.026	0.47PheCys: 0.47 ± 0.01	2.221PheAsp: 2.221 ± 0.02	2.106PheGlu: 2.106 ± 0.019	1.44PhePhe: 1.44 ± 0.019	2.813PheGly: 2.813 ± 0.026	0.815PheHis: 0.815 ± 0.012	1.521PheIle: 1.521 ± 0.016	1.375PheLys: 1.375 ± 0.017	3.202PheLeu: 3.202 ± 0.026	0.743PheMet: 0.743 ± 0.012	1.297PheAsn: 1.297 ± 0.015	1.786PhePro: 1.786 ± 0.02	1.211PheGln: 1.211 ± 0.016	1.893PheArg: 1.893 ± 0.018	2.691PheSer: 2.691 ± 0.022	2.02PheThr: 2.02 ± 0.019	2.421PheVal: 2.421 ± 0.022	0.57PheTrp: 0.57 ± 0.011	1.044PheTyr: 1.044 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	6.074GlyAla: 6.074 ± 0.041	0.758GlyCys: 0.758 ± 0.012	3.739GlyAsp: 3.739 ± 0.027	3.975GlyGlu: 3.975 ± 0.027	2.704GlyPhe: 2.704 ± 0.022	6.439GlyGly: 6.439 ± 0.059	1.643GlyHis: 1.643 ± 0.016	3.263GlyIle: 3.263 ± 0.023	3.586GlyLys: 3.586 ± 0.029	6.103GlyLeu: 6.103 ± 0.036	1.7GlyMet: 1.7 ± 0.02	2.524GlyAsn: 2.524 ± 0.023	3.281GlyPro: 3.281 ± 0.025	2.595GlyGln: 2.595 ± 0.026	4.485GlyArg: 4.485 ± 0.031	5.788GlySer: 5.788 ± 0.04	4.2GlyThr: 4.2 ± 0.03	4.757GlyVal: 4.757 ± 0.032	1.161GlyTrp: 1.161 ± 0.016	2.08GlyTyr: 2.08 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	2.044HisAla: 2.044 ± 0.02	0.273HisCys: 0.273 ± 0.007	1.354HisAsp: 1.354 ± 0.015	1.39HisGlu: 1.39 ± 0.018	0.903HisPhe: 0.903 ± 0.012	1.724HisGly: 1.724 ± 0.02	0.8HisHis: 0.8 ± 0.012	1.062HisIle: 1.062 ± 0.014	0.936HisLys: 0.936 ± 0.013	2.192HisLeu: 2.192 ± 0.021	0.448HisMet: 0.448 ± 0.009	0.834HisAsn: 0.834 ± 0.014	1.64HisPro: 1.64 ± 0.019	0.956HisGln: 0.956 ± 0.013	1.511HisArg: 1.511 ± 0.017	1.797HisSer: 1.797 ± 0.014	1.331HisThr: 1.331 ± 0.014	1.527HisVal: 1.527 ± 0.016	0.328HisTrp: 0.328 ± 0.007	0.703HisTyr: 0.703 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.142IleAla: 4.142 ± 0.026	0.59IleCys: 0.59 ± 0.009	2.714IleAsp: 2.714 ± 0.021	2.748IleGlu: 2.748 ± 0.019	1.652IlePhe: 1.652 ± 0.019	2.967IleGly: 2.967 ± 0.024	1.067IleHis: 1.067 ± 0.015	2.03IleIle: 2.03 ± 0.022	2.034IleLys: 2.034 ± 0.02	3.94IleLeu: 3.94 ± 0.031	0.889IleMet: 0.889 ± 0.012	1.629IleAsn: 1.629 ± 0.019	2.728IlePro: 2.728 ± 0.021	1.596IleGln: 1.596 ± 0.018	2.649IleArg: 2.649 ± 0.02	3.365IleSer: 3.365 ± 0.025	2.719IleThr: 2.719 ± 0.024	3.059IleVal: 3.059 ± 0.026	0.585IleTrp: 0.585 ± 0.012	1.21IleTyr: 1.21 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.562LysAla: 4.562 ± 0.036	0.386LysCys: 0.386 ± 0.009	2.89LysAsp: 2.89 ± 0.025	3.493LysGlu: 3.493 ± 0.028	1.339LysPhe: 1.339 ± 0.015	3.186LysGly: 3.186 ± 0.024	1.19LysHis: 1.19 ± 0.014	2.147LysIle: 2.147 ± 0.019	3.44LysLys: 3.44 ± 0.042	4.006LysLeu: 4.006 ± 0.032	1.029LysMet: 1.029 ± 0.015	1.658LysAsn: 1.658 ± 0.019	2.663LysPro: 2.663 ± 0.028	1.883LysGln: 1.883 ± 0.019	3.734LysArg: 3.734 ± 0.031	3.378LysSer: 3.378 ± 0.027	2.841LysThr: 2.841 ± 0.023	2.788LysVal: 2.788 ± 0.024	0.634LysTrp: 0.634 ± 0.01	1.278LysTyr: 1.278 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	8.177LeuAla: 8.177 ± 0.039	1.024LeuCys: 1.024 ± 0.014	5.144LeuAsp: 5.144 ± 0.032	5.543LeuGlu: 5.543 ± 0.047	3.128LeuPhe: 3.128 ± 0.027	5.849LeuGly: 5.849 ± 0.037	2.221LeuHis: 2.221 ± 0.021	3.519LeuIle: 3.519 ± 0.028	4.19LeuLys: 4.19 ± 0.034	8.356LeuLeu: 8.356 ± 0.048	1.726LeuMet: 1.726 ± 0.019	3.004LeuAsn: 3.004 ± 0.022	5.503LeuPro: 5.503 ± 0.038	3.833LeuGln: 3.833 ± 0.03	5.957LeuArg: 5.957 ± 0.037	7.081LeuSer: 7.081 ± 0.037	4.834LeuThr: 4.834 ± 0.031	5.431LeuVal: 5.431 ± 0.034	1.082LeuTrp: 1.082 ± 0.015	2.273LeuTyr: 2.273 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	2.182MetAla: 2.182 ± 0.02	0.216MetCys: 0.216 ± 0.006	1.239MetAsp: 1.239 ± 0.013	1.289MetGlu: 1.289 ± 0.015	0.727MetPhe: 0.727 ± 0.013	1.438MetGly: 1.438 ± 0.019	0.475MetHis: 0.475 ± 0.009	0.874MetIle: 0.874 ± 0.014	1.031MetLys: 1.031 ± 0.012	1.843MetLeu: 1.843 ± 0.018	0.535MetMet: 0.535 ± 0.01	0.786MetAsn: 0.786 ± 0.012	1.3MetPro: 1.3 ± 0.015	0.915MetGln: 0.915 ± 0.014	1.282MetArg: 1.282 ± 0.014	1.838MetSer: 1.838 ± 0.018	1.243MetThr: 1.243 ± 0.014	1.238MetVal: 1.238 ± 0.015	0.252MetTrp: 0.252 ± 0.007	0.491MetTyr: 0.491 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.339AsnAla: 3.339 ± 0.024	0.361AsnCys: 0.361 ± 0.007	1.903AsnAsp: 1.903 ± 0.018	2.01AsnGlu: 2.01 ± 0.019	1.279AsnPhe: 1.279 ± 0.014	3.098AsnGly: 3.098 ± 0.027	0.8AsnHis: 0.8 ± 0.01	1.823AsnIle: 1.823 ± 0.019	1.483AsnLys: 1.483 ± 0.017	3.014AsnLeu: 3.014 ± 0.027	0.774AsnMet: 0.774 ± 0.01	1.422AsnAsn: 1.422 ± 0.018	2.348AsnPro: 2.348 ± 0.022	1.2AsnGln: 1.2 ± 0.016	1.884AsnArg: 1.884 ± 0.02	2.554AsnSer: 2.554 ± 0.02	2.181AsnThr: 2.181 ± 0.02	2.365AsnVal: 2.365 ± 0.021	0.469AsnTrp: 0.469 ± 0.009	1.003AsnTyr: 1.003 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	5.643ProAla: 5.643 ± 0.044	0.396ProCys: 0.396 ± 0.01	3.123ProAsp: 3.123 ± 0.025	3.512ProGlu: 3.512 ± 0.027	1.961ProPhe: 1.961 ± 0.016	3.779ProGly: 3.779 ± 0.029	1.393ProHis: 1.393 ± 0.017	2.281ProIle: 2.281 ± 0.021	2.586ProLys: 2.586 ± 0.022	4.744ProLeu: 4.744 ± 0.032	1.063ProMet: 1.063 ± 0.015	2.108ProAsn: 2.108 ± 0.02	5.508ProPro: 5.508 ± 0.056	2.524ProGln: 2.524 ± 0.031	3.349ProArg: 3.349 ± 0.026	6.181ProSer: 6.181 ± 0.042	4.219ProThr: 4.219 ± 0.034	3.494ProVal: 3.494 ± 0.029	0.639ProTrp: 0.639 ± 0.011	1.524ProTyr: 1.524 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.588GlnAla: 3.588 ± 0.026	0.362GlnCys: 0.362 ± 0.008	1.995GlnAsp: 1.995 ± 0.018	2.361GlnGlu: 2.361 ± 0.024	1.13GlnPhe: 1.13 ± 0.013	2.463GlnGly: 2.463 ± 0.02	1.17GlnHis: 1.17 ± 0.016	1.744GlnIle: 1.744 ± 0.018	1.999GlnLys: 1.999 ± 0.022	3.491GlnLeu: 3.491 ± 0.028	0.879GlnMet: 0.879 ± 0.013	1.523GlnAsn: 1.523 ± 0.02	2.492GlnPro: 2.492 ± 0.028	2.756GlnGln: 2.756 ± 0.055	2.873GlnArg: 2.873 ± 0.024	3.113GlnSer: 3.113 ± 0.029	2.368GlnThr: 2.368 ± 0.021	2.073GlnVal: 2.073 ± 0.02	0.537GlnTrp: 0.537 ± 0.011	1.178GlnTyr: 1.178 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.368ArgAla: 5.368 ± 0.029	0.6ArgCys: 0.6 ± 0.011	3.531ArgAsp: 3.531 ± 0.031	4.194ArgGlu: 4.194 ± 0.037	2.091ArgPhe: 2.091 ± 0.022	3.989ArgGly: 3.989 ± 0.031	1.534ArgHis: 1.534 ± 0.018	2.795ArgIle: 2.795 ± 0.024	3.739ArgLys: 3.739 ± 0.029	5.535ArgLeu: 5.535 ± 0.033	1.377ArgMet: 1.377 ± 0.014	2.287ArgAsn: 2.287 ± 0.021	3.548ArgPro: 3.548 ± 0.03	2.692ArgGln: 2.692 ± 0.024	5.392ArgArg: 5.392 ± 0.041	4.854ArgSer: 4.854 ± 0.036	3.585ArgThr: 3.585 ± 0.028	3.555ArgVal: 3.555 ± 0.023	0.887ArgTrp: 0.887 ± 0.013	1.644ArgTyr: 1.644 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	7.491SerAla: 7.491 ± 0.044	0.7SerCys: 0.7 ± 0.012	4.195SerAsp: 4.195 ± 0.029	4.08SerGlu: 4.08 ± 0.027	2.766SerPhe: 2.766 ± 0.02	5.659SerGly: 5.659 ± 0.04	1.869SerHis: 1.869 ± 0.019	3.552SerIle: 3.552 ± 0.028	3.667SerLys: 3.667 ± 0.03	6.794SerLeu: 6.794 ± 0.039	1.624SerMet: 1.624 ± 0.014	2.993SerAsn: 2.993 ± 0.022	5.45SerPro: 5.45 ± 0.048	3.168SerGln: 3.168 ± 0.03	4.832SerArg: 4.832 ± 0.04	8.949SerSer: 8.949 ± 0.063	5.879SerThr: 5.879 ± 0.038	4.636SerVal: 4.636 ± 0.029	0.939SerTrp: 0.939 ± 0.013	2.009SerTyr: 2.009 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.936ThrAla: 5.936 ± 0.038	0.607ThrCys: 0.607 ± 0.01	2.897ThrAsp: 2.897 ± 0.022	3.117ThrGlu: 3.117 ± 0.026	2.139ThrPhe: 2.139 ± 0.02	4.23ThrGly: 4.23 ± 0.033	1.356ThrHis: 1.356 ± 0.017	2.887ThrIle: 2.887 ± 0.023	2.622ThrLys: 2.622 ± 0.022	5.387ThrLeu: 5.387 ± 0.034	1.194ThrMet: 1.194 ± 0.014	2.17ThrAsn: 2.17 ± 0.021	4.461ThrPro: 4.461 ± 0.032	2.163ThrGln: 2.163 ± 0.022	3.281ThrArg: 3.281 ± 0.025	5.656ThrSer: 5.656 ± 0.039	4.553ThrThr: 4.553 ± 0.042	3.851ThrVal: 3.851 ± 0.032	0.742ThrTrp: 0.742 ± 0.013	1.585ThrTyr: 1.585 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.779ValAla: 5.779 ± 0.036	0.725ValCys: 0.725 ± 0.011	3.894ValAsp: 3.894 ± 0.03	4.268ValGlu: 4.268 ± 0.036	2.355ValPhe: 2.355 ± 0.024	4.377ValGly: 4.377 ± 0.031	1.418ValHis: 1.418 ± 0.015	2.682ValIle: 2.682 ± 0.025	3.014ValLys: 3.014 ± 0.026	5.705ValLeu: 5.705 ± 0.036	1.327ValMet: 1.327 ± 0.016	2.181ValAsn: 2.181 ± 0.02	3.626ValPro: 3.626 ± 0.028	2.4ValGln: 2.4 ± 0.02	3.689ValArg: 3.689 ± 0.024	4.568ValSer: 4.568 ± 0.031	3.523ValThr: 3.523 ± 0.024	4.749ValVal: 4.749 ± 0.041	0.838ValTrp: 0.838 ± 0.012	1.705ValTyr: 1.705 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.061TrpAla: 1.061 ± 0.014	0.162TrpCys: 0.162 ± 0.005	0.798TrpAsp: 0.798 ± 0.013	0.809TrpGlu: 0.809 ± 0.012	0.485TrpPhe: 0.485 ± 0.01	0.858TrpGly: 0.858 ± 0.014	0.327TrpHis: 0.327 ± 0.007	0.664TrpIle: 0.664 ± 0.012	0.736TrpLys: 0.736 ± 0.011	1.249TrpLeu: 1.249 ± 0.014	0.34TrpMet: 0.34 ± 0.007	0.544TrpAsn: 0.544 ± 0.01	0.506TrpPro: 0.506 ± 0.009	0.541TrpGln: 0.541 ± 0.01	0.957TrpArg: 0.957 ± 0.013	0.968TrpSer: 0.968 ± 0.015	0.878TrpThr: 0.878 ± 0.014	0.799TrpVal: 0.799 ± 0.012	0.25TrpTrp: 0.25 ± 0.007	0.386TrpTyr: 0.386 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.26TyrAla: 2.26 ± 0.019	0.359TyrCys: 0.359 ± 0.007	1.674TyrAsp: 1.674 ± 0.019	1.548TyrGlu: 1.548 ± 0.016	1.113TyrPhe: 1.113 ± 0.015	2.095TyrGly: 2.095 ± 0.022	0.698TyrHis: 0.698 ± 0.012	1.258TyrIle: 1.258 ± 0.014	1.093TyrLys: 1.093 ± 0.014	2.527TyrLeu: 2.527 ± 0.022	0.578TyrMet: 0.578 ± 0.009	1.081TyrAsn: 1.081 ± 0.013	1.444TyrPro: 1.444 ± 0.015	1.081TyrGln: 1.081 ± 0.015	1.571TyrArg: 1.571 ± 0.018	1.926TyrSer: 1.926 ± 0.02	1.601TyrThr: 1.601 ± 0.016	1.609TyrVal: 1.609 ± 0.018	0.384TyrTrp: 0.384 ± 0.008	0.909TyrTyr: 0.909 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13291 proteins (6038804 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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