Amino acid dipepetide frequency for Spring viraemia of carp virus (strain ATCC VR-1390)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.94AlaAla: 3.94 ± 0.937
1.407AlaCys: 1.407 ± 0.445
2.815AlaAsp: 2.815 ± 0.431
2.252AlaGlu: 2.252 ± 0.933
0.844AlaPhe: 0.844 ± 0.73
2.252AlaGly: 2.252 ± 0.58
1.126AlaHis: 1.126 ± 0.504
2.815AlaIle: 2.815 ± 1.243
1.97AlaLys: 1.97 ± 0.638
5.348AlaLeu: 5.348 ± 1.064
0.563AlaMet: 0.563 ± 0.312
0.844AlaAsn: 0.844 ± 0.324
0.844AlaPro: 0.844 ± 0.455
1.407AlaGln: 1.407 ± 0.781
1.689AlaArg: 1.689 ± 0.373
3.377AlaSer: 3.377 ± 1.901
3.94AlaThr: 3.94 ± 1.291
2.533AlaVal: 2.533 ± 0.646
0.844AlaTrp: 0.844 ± 0.716
1.689AlaTyr: 1.689 ± 0.686
0.0AlaXaa: 0.0 ± 0.0
Cys
0.844CysAla: 0.844 ± 0.684
0.281CysCys: 0.281 ± 0.409
0.844CysAsp: 0.844 ± 0.455
1.126CysGlu: 1.126 ± 0.668
0.281CysPhe: 0.281 ± 0.156
1.407CysGly: 1.407 ± 0.386
0.563CysHis: 0.563 ± 0.334
1.126CysIle: 1.126 ± 0.625
1.407CysLys: 1.407 ± 0.75
1.407CysLeu: 1.407 ± 0.781
0.0CysMet: 0.0 ± 0.0
1.126CysAsn: 1.126 ± 0.436
1.126CysPro: 1.126 ± 0.383
1.97CysGln: 1.97 ± 0.564
1.407CysArg: 1.407 ± 0.698
0.563CysSer: 0.563 ± 0.369
0.844CysThr: 0.844 ± 0.324
1.407CysVal: 1.407 ± 0.698
0.281CysTrp: 0.281 ± 0.156
0.281CysTyr: 0.281 ± 0.388
0.0CysXaa: 0.0 ± 0.0
Asp
1.126AspAla: 1.126 ± 0.37
0.281AspCys: 0.281 ± 0.393
3.659AspAsp: 3.659 ± 2.242
4.222AspGlu: 4.222 ± 2.415
1.126AspPhe: 1.126 ± 0.479
3.377AspGly: 3.377 ± 1.56
0.844AspHis: 0.844 ± 0.324
3.94AspIle: 3.94 ± 1.033
2.252AspLys: 2.252 ± 0.564
6.192AspLeu: 6.192 ± 2.128
1.689AspMet: 1.689 ± 1.093
2.533AspAsn: 2.533 ± 1.037
2.533AspPro: 2.533 ± 0.767
1.97AspGln: 1.97 ± 0.538
2.533AspArg: 2.533 ± 0.687
5.348AspSer: 5.348 ± 0.829
3.377AspThr: 3.377 ± 1.008
3.94AspVal: 3.94 ± 1.197
3.096AspTrp: 3.096 ± 0.591
2.815AspTyr: 2.815 ± 0.886
0.0AspXaa: 0.0 ± 0.0
Glu
2.533GluAla: 2.533 ± 0.684
1.97GluCys: 1.97 ± 1.133
5.348GluAsp: 5.348 ± 3.078
8.725GluGlu: 8.725 ± 4.239
1.97GluPhe: 1.97 ± 0.462
4.503GluGly: 4.503 ± 0.978
2.252GluHis: 2.252 ± 0.934
4.222GluIle: 4.222 ± 0.686
5.066GluLys: 5.066 ± 0.681
5.066GluLeu: 5.066 ± 0.987
2.252GluMet: 2.252 ± 0.56
1.97GluAsn: 1.97 ± 0.692
2.533GluPro: 2.533 ± 1.804
1.126GluGln: 1.126 ± 0.471
2.533GluArg: 2.533 ± 0.312
5.91GluSer: 5.91 ± 1.389
3.94GluThr: 3.94 ± 1.182
4.503GluVal: 4.503 ± 0.995
1.97GluTrp: 1.97 ± 0.827
1.689GluTyr: 1.689 ± 0.614
0.0GluXaa: 0.0 ± 0.0
Phe
0.844PheAla: 0.844 ± 0.324
0.844PheCys: 0.844 ± 0.324
1.689PheAsp: 1.689 ± 1.222
2.815PheGlu: 2.815 ± 0.892
1.689PhePhe: 1.689 ± 0.619
3.377PheGly: 3.377 ± 0.925
0.281PheHis: 0.281 ± 0.393
1.407PheIle: 1.407 ± 0.386
1.97PheLys: 1.97 ± 0.702
3.94PheLeu: 3.94 ± 0.561
0.844PheMet: 0.844 ± 0.413
1.689PheAsn: 1.689 ± 1.082
2.533PhePro: 2.533 ± 0.535
1.689PheGln: 1.689 ± 0.466
3.096PheArg: 3.096 ± 0.587
2.533PheSer: 2.533 ± 0.713
1.407PheThr: 1.407 ± 0.533
1.126PheVal: 1.126 ± 0.383
0.844PheTrp: 0.844 ± 0.457
0.844PheTyr: 0.844 ± 0.48
0.0PheXaa: 0.0 ± 0.0
Gly
1.689GlyAla: 1.689 ± 0.937
0.281GlyCys: 0.281 ± 0.156
4.785GlyAsp: 4.785 ± 0.881
3.096GlyGlu: 3.096 ± 0.803
2.815GlyPhe: 2.815 ± 0.826
3.659GlyGly: 3.659 ± 1.194
2.252GlyHis: 2.252 ± 0.74
5.629GlyIle: 5.629 ± 1.434
4.503GlyLys: 4.503 ± 0.65
9.288GlyLeu: 9.288 ± 1.525
1.407GlyMet: 1.407 ± 0.367
3.94GlyAsn: 3.94 ± 1.776
2.533GlyPro: 2.533 ± 0.689
2.533GlyGln: 2.533 ± 0.684
3.096GlyArg: 3.096 ± 0.569
4.222GlySer: 4.222 ± 1.046
5.629GlyThr: 5.629 ± 2.523
2.533GlyVal: 2.533 ± 1.043
1.689GlyTrp: 1.689 ± 1.003
1.407GlyTyr: 1.407 ± 0.574
0.0GlyXaa: 0.0 ± 0.0
His
1.126HisAla: 1.126 ± 0.668
0.563HisCys: 0.563 ± 0.447
0.844HisAsp: 0.844 ± 0.455
1.407HisGlu: 1.407 ± 1.202
1.689HisPhe: 1.689 ± 0.7
1.126HisGly: 1.126 ± 0.402
1.126HisHis: 1.126 ± 0.383
1.97HisIle: 1.97 ± 0.692
1.97HisLys: 1.97 ± 0.655
1.689HisLeu: 1.689 ± 0.396
0.0HisMet: 0.0 ± 0.0
1.126HisAsn: 1.126 ± 0.625
2.533HisPro: 2.533 ± 0.687
0.844HisGln: 0.844 ± 0.413
1.689HisArg: 1.689 ± 0.64
2.815HisSer: 2.815 ± 1.426
0.563HisThr: 0.563 ± 0.312
2.815HisVal: 2.815 ± 0.934
0.563HisTrp: 0.563 ± 0.334
1.97HisTyr: 1.97 ± 0.752
0.0HisXaa: 0.0 ± 0.0
Ile
1.97IleAla: 1.97 ± 0.574
1.689IleCys: 1.689 ± 0.466
5.066IleAsp: 5.066 ± 2.68
4.222IleGlu: 4.222 ± 0.473
1.689IlePhe: 1.689 ± 1.003
5.629IleGly: 5.629 ± 1.384
1.97IleHis: 1.97 ± 1.391
3.94IleIle: 3.94 ± 1.599
5.066IleLys: 5.066 ± 1.828
3.659IleLeu: 3.659 ± 1.395
1.97IleMet: 1.97 ± 0.564
2.533IleAsn: 2.533 ± 1.043
4.785IlePro: 4.785 ± 0.884
3.096IleGln: 3.096 ± 0.694
5.066IleArg: 5.066 ± 0.625
5.91IleSer: 5.91 ± 0.553
2.533IleThr: 2.533 ± 0.4
3.377IleVal: 3.377 ± 0.642
0.844IleTrp: 0.844 ± 0.324
1.97IleTyr: 1.97 ± 0.752
0.0IleXaa: 0.0 ± 0.0
Lys
2.815LysAla: 2.815 ± 0.77
0.844LysCys: 0.844 ± 0.324
2.533LysAsp: 2.533 ± 0.4
5.629LysGlu: 5.629 ± 2.487
2.252LysPhe: 2.252 ± 0.957
4.222LysGly: 4.222 ± 0.894
1.407LysHis: 1.407 ± 0.406
4.503LysIle: 4.503 ± 1.645
2.252LysLys: 2.252 ± 0.896
7.599LysLeu: 7.599 ± 0.775
1.97LysMet: 1.97 ± 0.538
2.533LysAsn: 2.533 ± 0.684
2.252LysPro: 2.252 ± 1.267
1.97LysGln: 1.97 ± 0.638
4.503LysArg: 4.503 ± 0.429
4.222LysSer: 4.222 ± 1.177
5.066LysThr: 5.066 ± 0.881
3.659LysVal: 3.659 ± 0.733
1.126LysTrp: 1.126 ± 0.423
1.97LysTyr: 1.97 ± 1.5
0.0LysXaa: 0.0 ± 0.0
Leu
4.222LeuAla: 4.222 ± 1.332
1.407LeuCys: 1.407 ± 0.337
5.066LeuAsp: 5.066 ± 0.919
5.91LeuGlu: 5.91 ± 0.956
2.815LeuPhe: 2.815 ± 1.071
5.348LeuGly: 5.348 ± 0.598
1.97LeuHis: 1.97 ± 0.902
7.881LeuIle: 7.881 ± 0.748
6.755LeuLys: 6.755 ± 1.511
8.162LeuLeu: 8.162 ± 1.556
3.096LeuMet: 3.096 ± 0.844
5.066LeuAsn: 5.066 ± 0.987
3.377LeuPro: 3.377 ± 1.077
2.815LeuGln: 2.815 ± 0.614
6.473LeuArg: 6.473 ± 2.105
8.725LeuSer: 8.725 ± 2.773
5.91LeuThr: 5.91 ± 1.4
4.785LeuVal: 4.785 ± 1.46
0.844LeuTrp: 0.844 ± 0.436
3.377LeuTyr: 3.377 ± 1.115
0.0LeuXaa: 0.0 ± 0.0
Met
1.97MetAla: 1.97 ± 0.655
0.0MetCys: 0.0 ± 0.0
1.126MetAsp: 1.126 ± 0.504
1.689MetGlu: 1.689 ± 0.467
1.689MetPhe: 1.689 ± 0.534
2.252MetGly: 2.252 ± 0.582
0.563MetHis: 0.563 ± 0.312
1.126MetIle: 1.126 ± 0.383
2.252MetLys: 2.252 ± 0.992
2.252MetLeu: 2.252 ± 0.945
1.407MetMet: 1.407 ± 0.75
0.844MetAsn: 0.844 ± 0.436
1.126MetPro: 1.126 ± 1.079
0.563MetGln: 0.563 ± 0.312
2.252MetArg: 2.252 ± 0.469
3.659MetSer: 3.659 ± 1.011
1.689MetThr: 1.689 ± 0.614
0.563MetVal: 0.563 ± 0.369
0.0MetTrp: 0.0 ± 0.0
1.126MetTyr: 1.126 ± 0.668
0.0MetXaa: 0.0 ± 0.0
Asn
2.815AsnAla: 2.815 ± 1.684
1.689AsnCys: 1.689 ± 0.467
0.844AsnAsp: 0.844 ± 0.349
1.407AsnGlu: 1.407 ± 0.442
0.844AsnPhe: 0.844 ± 0.324
4.503AsnGly: 4.503 ± 1.432
2.252AsnHis: 2.252 ± 0.897
1.407AsnIle: 1.407 ± 0.639
3.94AsnLys: 3.94 ± 1.458
5.066AsnLeu: 5.066 ± 1.2
0.844AsnMet: 0.844 ± 0.324
2.815AsnAsn: 2.815 ± 1.193
1.97AsnPro: 1.97 ± 0.462
1.126AsnGln: 1.126 ± 0.625
0.563AsnArg: 0.563 ± 0.312
3.377AsnSer: 3.377 ± 1.325
2.252AsnThr: 2.252 ± 0.957
1.407AsnVal: 1.407 ± 1.06
0.844AsnTrp: 0.844 ± 0.413
1.689AsnTyr: 1.689 ± 0.373
0.0AsnXaa: 0.0 ± 0.0
Pro
1.97ProAla: 1.97 ± 0.462
0.281ProCys: 0.281 ± 0.156
4.503ProAsp: 4.503 ± 1.319
0.563ProGlu: 0.563 ± 0.447
1.97ProPhe: 1.97 ± 0.351
1.126ProGly: 1.126 ± 0.62
2.252ProHis: 2.252 ± 1.022
3.377ProIle: 3.377 ± 1.295
1.97ProLys: 1.97 ± 0.638
4.222ProLeu: 4.222 ± 0.9
0.844ProMet: 0.844 ± 0.615
1.689ProAsn: 1.689 ± 0.483
2.533ProPro: 2.533 ± 0.684
1.126ProGln: 1.126 ± 0.668
3.377ProArg: 3.377 ± 0.645
4.503ProSer: 4.503 ± 0.365
3.377ProThr: 3.377 ± 0.618
3.659ProVal: 3.659 ± 0.945
0.844ProTrp: 0.844 ± 0.436
0.844ProTyr: 0.844 ± 0.895
0.0ProXaa: 0.0 ± 0.0
Gln
2.252GlnAla: 2.252 ± 0.58
0.563GlnCys: 0.563 ± 0.574
1.126GlnAsp: 1.126 ± 0.625
1.689GlnGlu: 1.689 ± 0.373
1.126GlnPhe: 1.126 ± 0.471
2.815GlnGly: 2.815 ± 0.265
1.407GlnHis: 1.407 ± 0.85
2.815GlnIle: 2.815 ± 1.219
2.533GlnLys: 2.533 ± 0.983
1.689GlnLeu: 1.689 ± 0.662
0.844GlnMet: 0.844 ± 0.455
1.97GlnAsn: 1.97 ± 1.093
1.126GlnPro: 1.126 ± 0.799
0.844GlnGln: 0.844 ± 0.349
1.126GlnArg: 1.126 ± 0.383
1.97GlnSer: 1.97 ± 0.752
2.252GlnThr: 2.252 ± 0.659
1.97GlnVal: 1.97 ± 0.943
0.281GlnTrp: 0.281 ± 0.388
1.97GlnTyr: 1.97 ± 0.462
0.0GlnXaa: 0.0 ± 0.0
Arg
1.689ArgAla: 1.689 ± 0.698
1.407ArgCys: 1.407 ± 0.406
2.252ArgAsp: 2.252 ± 0.64
7.318ArgGlu: 7.318 ± 1.797
3.096ArgPhe: 3.096 ± 0.587
3.94ArgGly: 3.94 ± 1.348
1.689ArgHis: 1.689 ± 0.614
3.096ArgIle: 3.096 ± 0.691
2.533ArgLys: 2.533 ± 0.493
3.94ArgLeu: 3.94 ± 1.287
1.689ArgMet: 1.689 ± 0.753
1.97ArgAsn: 1.97 ± 0.618
1.407ArgPro: 1.407 ± 0.386
1.126ArgGln: 1.126 ± 0.675
2.252ArgArg: 2.252 ± 0.469
4.503ArgSer: 4.503 ± 0.65
1.97ArgThr: 1.97 ± 0.462
4.222ArgVal: 4.222 ± 1.255
1.689ArgTrp: 1.689 ± 0.373
1.689ArgTyr: 1.689 ± 0.856
0.0ArgXaa: 0.0 ± 0.0
Ser
4.222SerAla: 4.222 ± 0.989
1.689SerCys: 1.689 ± 0.64
3.377SerAsp: 3.377 ± 0.814
5.629SerGlu: 5.629 ± 1.698
1.97SerPhe: 1.97 ± 0.759
5.348SerGly: 5.348 ± 1.529
1.126SerHis: 1.126 ± 0.402
5.91SerIle: 5.91 ± 0.284
6.755SerLys: 6.755 ± 1.981
8.725SerLeu: 8.725 ± 1.482
1.97SerMet: 1.97 ± 0.538
3.096SerAsn: 3.096 ± 0.276
2.533SerPro: 2.533 ± 1.037
2.252SerGln: 2.252 ± 0.934
4.785SerArg: 4.785 ± 1.353
7.599SerSer: 7.599 ± 2.86
4.785SerThr: 4.785 ± 0.924
6.473SerVal: 6.473 ± 0.907
1.97SerTrp: 1.97 ± 0.462
3.377SerTyr: 3.377 ± 0.746
0.0SerXaa: 0.0 ± 0.0
Thr
2.252ThrAla: 2.252 ± 0.399
0.844ThrCys: 0.844 ± 0.324
2.815ThrAsp: 2.815 ± 0.855
3.377ThrGlu: 3.377 ± 0.432
2.252ThrPhe: 2.252 ± 0.707
4.503ThrGly: 4.503 ± 0.644
2.533ThrHis: 2.533 ± 0.637
4.222ThrIle: 4.222 ± 1.204
3.096ThrLys: 3.096 ± 0.871
5.348ThrLeu: 5.348 ± 1.302
2.533ThrMet: 2.533 ± 0.816
2.252ThrAsn: 2.252 ± 0.569
1.97ThrPro: 1.97 ± 0.909
1.126ThrGln: 1.126 ± 0.625
0.844ThrArg: 0.844 ± 0.469
3.94ThrSer: 3.94 ± 1.091
3.94ThrThr: 3.94 ± 1.171
4.785ThrVal: 4.785 ± 1.416
1.407ThrTrp: 1.407 ± 0.533
3.377ThrTyr: 3.377 ± 1.182
0.0ThrXaa: 0.0 ± 0.0
Val
2.533ValAla: 2.533 ± 2.062
1.126ValCys: 1.126 ± 0.383
5.629ValAsp: 5.629 ± 1.353
4.503ValGlu: 4.503 ± 1.59
3.096ValPhe: 3.096 ± 1.272
2.815ValGly: 2.815 ± 0.696
1.407ValHis: 1.407 ± 0.406
3.659ValIle: 3.659 ± 1.298
3.096ValLys: 3.096 ± 0.918
4.503ValLeu: 4.503 ± 1.287
2.533ValMet: 2.533 ± 0.817
1.407ValAsn: 1.407 ± 0.668
5.348ValPro: 5.348 ± 1.226
1.97ValGln: 1.97 ± 0.45
3.377ValArg: 3.377 ± 0.66
5.629ValSer: 5.629 ± 2.079
2.252ValThr: 2.252 ± 0.24
2.533ValVal: 2.533 ± 1.129
0.844ValTrp: 0.844 ± 0.349
1.689ValTyr: 1.689 ± 0.619
0.0ValXaa: 0.0 ± 0.0
Trp
0.281TrpAla: 0.281 ± 0.409
0.0TrpCys: 0.0 ± 0.0
1.689TrpAsp: 1.689 ± 0.369
3.377TrpGlu: 3.377 ± 1.184
0.563TrpPhe: 0.563 ± 0.312
1.97TrpGly: 1.97 ± 0.987
0.281TrpHis: 0.281 ± 0.156
2.815TrpIle: 2.815 ± 1.017
1.407TrpLys: 1.407 ± 0.386
0.844TrpLeu: 0.844 ± 0.349
0.563TrpMet: 0.563 ± 0.369
0.281TrpAsn: 0.281 ± 0.156
0.563TrpPro: 0.563 ± 0.312
0.844TrpGln: 0.844 ± 0.324
0.0TrpArg: 0.0 ± 0.0
1.126TrpSer: 1.126 ± 0.625
0.563TrpThr: 0.563 ± 0.369
1.689TrpVal: 1.689 ± 0.914
0.0TrpTrp: 0.0 ± 0.0
1.126TrpTyr: 1.126 ± 0.37
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.407TyrAla: 1.407 ± 0.894
1.126TyrCys: 1.126 ± 0.625
0.844TyrAsp: 0.844 ± 0.529
1.126TyrGlu: 1.126 ± 0.504
1.689TyrPhe: 1.689 ± 0.662
3.096TyrGly: 3.096 ± 0.691
1.126TyrHis: 1.126 ± 0.504
1.126TyrIle: 1.126 ± 1.136
2.533TyrLys: 2.533 ± 0.816
5.066TyrLeu: 5.066 ± 0.835
0.844TyrMet: 0.844 ± 0.716
1.97TyrAsn: 1.97 ± 0.949
1.407TyrPro: 1.407 ± 0.467
1.97TyrGln: 1.97 ± 0.957
2.815TyrArg: 2.815 ± 1.546
3.659TyrSer: 3.659 ± 1.16
1.126TyrThr: 1.126 ± 0.383
1.97TyrVal: 1.97 ± 1.184
0.0TyrTrp: 0.0 ± 0.0
0.563TyrTyr: 0.563 ± 0.312
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3554 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski