Amino acid dipepetide frequency for Carnation mottle virus (CarMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.929AlaAla: 7.929 ± 1.274
2.973AlaCys: 2.973 ± 0.626
2.973AlaAsp: 2.973 ± 0.576
4.46AlaGlu: 4.46 ± 0.727
1.487AlaPhe: 1.487 ± 0.328
5.946AlaGly: 5.946 ± 0.869
1.982AlaHis: 1.982 ± 0.68
4.955AlaIle: 4.955 ± 0.743
4.955AlaLys: 4.955 ± 1.154
6.442AlaLeu: 6.442 ± 0.398
2.478AlaMet: 2.478 ± 0.231
4.46AlaAsn: 4.46 ± 1.133
1.982AlaPro: 1.982 ± 0.68
1.982AlaGln: 1.982 ± 0.942
2.478AlaArg: 2.478 ± 0.231
6.442AlaSer: 6.442 ± 1.427
1.487AlaThr: 1.487 ± 0.328
4.46AlaVal: 4.46 ± 0.985
0.991AlaTrp: 0.991 ± 0.34
1.982AlaTyr: 1.982 ± 0.68
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.478CysGlu: 2.478 ± 0.231
0.991CysPhe: 0.991 ± 0.34
2.478CysGly: 2.478 ± 0.714
0.0CysHis: 0.0 ± 0.0
1.487CysIle: 1.487 ± 0.328
0.991CysLys: 0.991 ± 0.34
2.973CysLeu: 2.973 ± 1.02
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.982CysPro: 1.982 ± 0.68
0.991CysGln: 0.991 ± 0.34
1.982CysArg: 1.982 ± 0.68
0.496CysSer: 0.496 ± 0.627
1.487CysThr: 1.487 ± 0.686
3.964CysVal: 3.964 ± 1.36
0.991CysTrp: 0.991 ± 0.34
2.478CysTyr: 2.478 ± 0.714
0.0CysXaa: 0.0 ± 0.0
Asp
3.469AspAla: 3.469 ± 0.918
2.973AspCys: 2.973 ± 1.02
1.982AspAsp: 1.982 ± 0.942
0.991AspGlu: 0.991 ± 0.34
0.496AspPhe: 0.496 ± 0.627
4.955AspGly: 4.955 ± 0.463
0.0AspHis: 0.0 ± 0.0
2.478AspIle: 2.478 ± 0.78
2.973AspLys: 2.973 ± 1.783
2.973AspLeu: 2.973 ± 0.657
1.982AspMet: 1.982 ± 0.68
0.991AspAsn: 0.991 ± 0.34
2.478AspPro: 2.478 ± 0.231
1.982AspGln: 1.982 ± 0.68
2.973AspArg: 2.973 ± 1.02
4.46AspSer: 4.46 ± 0.853
0.991AspThr: 0.991 ± 1.255
1.487AspVal: 1.487 ± 0.328
0.496AspTrp: 0.496 ± 0.627
1.487AspTyr: 1.487 ± 0.328
0.0AspXaa: 0.0 ± 0.0
Glu
1.982GluAla: 1.982 ± 0.68
0.991GluCys: 0.991 ± 0.34
1.487GluAsp: 1.487 ± 0.328
3.964GluGlu: 3.964 ± 1.36
2.973GluPhe: 2.973 ± 1.02
4.955GluGly: 4.955 ± 0.463
1.982GluHis: 1.982 ± 0.68
2.973GluIle: 2.973 ± 1.02
3.469GluLys: 3.469 ± 0.48
4.955GluLeu: 4.955 ± 1.588
3.469GluMet: 3.469 ± 0.48
2.478GluAsn: 2.478 ± 0.231
1.982GluPro: 1.982 ± 0.68
0.496GluGln: 0.496 ± 0.627
6.442GluArg: 6.442 ± 1.727
1.982GluSer: 1.982 ± 0.754
3.964GluThr: 3.964 ± 0.455
6.938GluVal: 6.938 ± 2.005
0.0GluTrp: 0.0 ± 0.0
0.991GluTyr: 0.991 ± 0.34
0.0GluXaa: 0.0 ± 0.0
Phe
0.991PheAla: 0.991 ± 0.34
1.487PheCys: 1.487 ± 0.686
4.46PheAsp: 4.46 ± 0.799
2.973PheGlu: 2.973 ± 0.657
0.991PhePhe: 0.991 ± 0.34
3.469PheGly: 3.469 ± 0.48
0.991PheHis: 0.991 ± 0.34
1.982PheIle: 1.982 ± 0.942
0.991PheLys: 0.991 ± 0.34
0.991PheLeu: 0.991 ± 0.34
1.487PheMet: 1.487 ± 0.605
4.46PheAsn: 4.46 ± 0.66
1.487PhePro: 1.487 ± 0.328
0.991PheGln: 0.991 ± 0.34
0.0PheArg: 0.0 ± 0.0
1.487PheSer: 1.487 ± 0.686
2.478PheThr: 2.478 ± 1.35
0.991PheVal: 0.991 ± 0.34
0.0PheTrp: 0.0 ± 0.0
4.46PheTyr: 4.46 ± 0.799
0.0PheXaa: 0.0 ± 0.0
Gly
1.982GlyAla: 1.982 ± 0.68
1.982GlyCys: 1.982 ± 0.68
5.946GlyAsp: 5.946 ± 0.673
2.973GlyGlu: 2.973 ± 0.657
6.938GlyPhe: 6.938 ± 1.078
7.929GlyGly: 7.929 ± 1.618
0.991GlyHis: 0.991 ± 0.34
2.478GlyIle: 2.478 ± 0.231
5.451GlyLys: 5.451 ± 2.806
7.929GlyLeu: 7.929 ± 2.003
1.982GlyMet: 1.982 ± 0.68
5.451GlyAsn: 5.451 ± 1.22
2.973GlyPro: 2.973 ± 0.657
1.982GlyGln: 1.982 ± 0.942
3.964GlyArg: 3.964 ± 0.455
1.982GlySer: 1.982 ± 0.68
0.991GlyThr: 0.991 ± 1.255
5.946GlyVal: 5.946 ± 0.833
3.469GlyTrp: 3.469 ± 0.48
4.46GlyTyr: 4.46 ± 0.799
0.0GlyXaa: 0.0 ± 0.0
His
0.991HisAla: 0.991 ± 0.34
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.991HisGlu: 0.991 ± 0.34
1.487HisPhe: 1.487 ± 0.667
0.991HisGly: 0.991 ± 0.34
0.991HisHis: 0.991 ± 0.34
1.982HisIle: 1.982 ± 1.081
0.0HisLys: 0.0 ± 0.0
3.469HisLeu: 3.469 ± 0.884
0.0HisMet: 0.0 ± 0.0
0.991HisAsn: 0.991 ± 0.34
0.991HisPro: 0.991 ± 0.34
0.0HisGln: 0.0 ± 0.0
0.991HisArg: 0.991 ± 0.34
2.973HisSer: 2.973 ± 1.02
1.982HisThr: 1.982 ± 0.68
2.478HisVal: 2.478 ± 0.231
0.991HisTrp: 0.991 ± 0.34
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.442IleAla: 6.442 ± 0.398
0.991IleCys: 0.991 ± 0.34
1.982IleAsp: 1.982 ± 0.68
4.955IleGlu: 4.955 ± 1.561
0.0IlePhe: 0.0 ± 0.0
3.964IleGly: 3.964 ± 0.511
0.496IleHis: 0.496 ± 0.715
0.991IleIle: 0.991 ± 1.16
1.982IleLys: 1.982 ± 0.68
2.973IleLeu: 2.973 ± 0.657
0.0IleMet: 0.0 ± 0.0
1.982IleAsn: 1.982 ± 0.68
0.991IlePro: 0.991 ± 1.255
1.487IleGln: 1.487 ± 0.328
7.433IleArg: 7.433 ± 1.084
4.46IleSer: 4.46 ± 2.509
4.955IleThr: 4.955 ± 0.463
2.973IleVal: 2.973 ± 1.918
1.982IleTrp: 1.982 ± 0.68
0.991IleTyr: 0.991 ± 0.34
0.0IleXaa: 0.0 ± 0.0
Lys
4.46LysAla: 4.46 ± 0.799
0.991LysCys: 0.991 ± 0.34
2.973LysAsp: 2.973 ± 0.576
5.946LysGlu: 5.946 ± 2.04
1.982LysPhe: 1.982 ± 0.68
3.469LysGly: 3.469 ± 1.263
1.487LysHis: 1.487 ± 0.328
6.938LysIle: 6.938 ± 0.64
1.982LysLys: 1.982 ± 0.68
2.478LysLeu: 2.478 ± 1.566
1.487LysMet: 1.487 ± 0.617
1.982LysAsn: 1.982 ± 0.68
1.982LysPro: 1.982 ± 0.754
2.478LysGln: 2.478 ± 1.7
3.469LysArg: 3.469 ± 0.48
3.469LysSer: 3.469 ± 0.48
3.469LysThr: 3.469 ± 2.38
0.991LysVal: 0.991 ± 1.255
0.496LysTrp: 0.496 ± 0.627
3.964LysTyr: 3.964 ± 0.455
0.991LysXaa: 0.991 ± 0.34
Leu
7.929LeuAla: 7.929 ± 1.72
0.0LeuCys: 0.0 ± 0.0
2.973LeuAsp: 2.973 ± 1.02
2.973LeuGlu: 2.973 ± 1.02
1.487LeuPhe: 1.487 ± 0.328
2.973LeuGly: 2.973 ± 0.657
0.496LeuHis: 0.496 ± 0.814
6.442LeuIle: 6.442 ± 1.198
6.442LeuLys: 6.442 ± 1.466
7.433LeuLeu: 7.433 ± 1.883
3.469LeuMet: 3.469 ± 0.884
3.964LeuAsn: 3.964 ± 1.359
1.487LeuPro: 1.487 ± 0.686
0.991LeuGln: 0.991 ± 1.255
5.946LeuArg: 5.946 ± 0.833
3.964LeuSer: 3.964 ± 3.123
4.955LeuThr: 4.955 ± 0.602
12.389LeuVal: 12.389 ± 0.747
0.991LeuTrp: 0.991 ± 0.34
0.991LeuTyr: 0.991 ± 0.34
0.0LeuXaa: 0.0 ± 0.0
Met
3.964MetAla: 3.964 ± 1.36
0.991MetCys: 0.991 ± 0.34
0.496MetAsp: 0.496 ± 0.715
1.982MetGlu: 1.982 ± 0.942
0.0MetPhe: 0.0 ± 0.0
1.982MetGly: 1.982 ± 0.68
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.982MetLys: 1.982 ± 0.68
2.478MetLeu: 2.478 ± 1.259
2.478MetMet: 2.478 ± 0.321
1.487MetAsn: 1.487 ± 0.328
0.496MetPro: 0.496 ± 0.814
0.991MetGln: 0.991 ± 0.34
0.0MetArg: 0.0 ± 0.0
3.469MetSer: 3.469 ± 0.48
0.991MetThr: 0.991 ± 1.255
2.973MetVal: 2.973 ± 1.02
0.991MetTrp: 0.991 ± 0.34
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.973AsnAla: 2.973 ± 1.02
1.982AsnCys: 1.982 ± 0.68
1.982AsnAsp: 1.982 ± 0.942
1.487AsnGlu: 1.487 ± 0.328
0.991AsnPhe: 0.991 ± 1.018
5.946AsnGly: 5.946 ± 0.802
3.964AsnHis: 3.964 ± 1.36
0.991AsnIle: 0.991 ± 0.34
3.964AsnLys: 3.964 ± 0.455
4.46AsnLeu: 4.46 ± 1.133
0.0AsnMet: 0.0 ± 0.0
1.982AsnAsn: 1.982 ± 0.68
2.973AsnPro: 2.973 ± 0.657
2.973AsnGln: 2.973 ± 0.626
4.46AsnArg: 4.46 ± 1.277
0.991AsnSer: 0.991 ± 1.16
1.982AsnThr: 1.982 ± 0.68
5.946AsnVal: 5.946 ± 1.005
0.496AsnTrp: 0.496 ± 0.715
1.487AsnTyr: 1.487 ± 0.686
0.0AsnXaa: 0.0 ± 0.0
Pro
3.469ProAla: 3.469 ± 0.918
0.0ProCys: 0.0 ± 0.0
1.982ProAsp: 1.982 ± 0.68
0.991ProGlu: 0.991 ± 0.34
0.0ProPhe: 0.0 ± 0.0
1.982ProGly: 1.982 ± 0.942
0.0ProHis: 0.0 ± 0.0
0.496ProIle: 0.496 ± 0.627
0.991ProLys: 0.991 ± 0.34
4.955ProLeu: 4.955 ± 0.602
0.0ProMet: 0.0 ± 0.0
1.487ProAsn: 1.487 ± 0.686
1.982ProPro: 1.982 ± 2.253
2.478ProGln: 2.478 ± 0.231
4.955ProArg: 4.955 ± 1.588
4.46ProSer: 4.46 ± 0.727
3.469ProThr: 3.469 ± 2.819
6.938ProVal: 6.938 ± 1.303
0.0ProTrp: 0.0 ± 0.0
0.991ProTyr: 0.991 ± 0.34
0.0ProXaa: 0.0 ± 0.0
Gln
1.982GlnAla: 1.982 ± 0.942
1.982GlnCys: 1.982 ± 0.68
0.0GlnAsp: 0.0 ± 0.0
0.991GlnGlu: 0.991 ± 0.34
0.991GlnPhe: 0.991 ± 0.34
1.982GlnGly: 1.982 ± 0.68
2.478GlnHis: 2.478 ± 0.714
1.982GlnIle: 1.982 ± 0.868
2.478GlnLys: 2.478 ± 1.217
1.982GlnLeu: 1.982 ± 0.942
2.478GlnMet: 2.478 ± 0.627
0.991GlnAsn: 0.991 ± 0.34
2.478GlnPro: 2.478 ± 0.231
1.487GlnGln: 1.487 ± 0.686
0.991GlnArg: 0.991 ± 0.34
0.991GlnSer: 0.991 ± 0.34
1.982GlnThr: 1.982 ± 0.942
0.0GlnVal: 0.0 ± 0.0
1.487GlnTrp: 1.487 ± 0.328
0.496GlnTyr: 0.496 ± 0.627
0.0GlnXaa: 0.0 ± 0.0
Arg
5.451ArgAla: 5.451 ± 1.188
1.487ArgCys: 1.487 ± 0.686
2.478ArgAsp: 2.478 ± 0.231
1.982ArgGlu: 1.982 ± 0.68
6.442ArgPhe: 6.442 ± 1.466
6.442ArgGly: 6.442 ± 0.562
1.982ArgHis: 1.982 ± 0.68
3.964ArgIle: 3.964 ± 0.455
5.451ArgLys: 5.451 ± 1.578
2.478ArgLeu: 2.478 ± 0.714
2.973ArgMet: 2.973 ± 0.657
1.982ArgAsn: 1.982 ± 0.942
0.991ArgPro: 0.991 ± 1.255
0.991ArgGln: 0.991 ± 0.34
6.442ArgArg: 6.442 ± 0.562
4.46ArgSer: 4.46 ± 1.277
2.478ArgThr: 2.478 ± 0.231
5.946ArgVal: 5.946 ± 0.673
0.991ArgTrp: 0.991 ± 0.34
2.973ArgTyr: 2.973 ± 1.02
0.0ArgXaa: 0.0 ± 0.0
Ser
6.938SerAla: 6.938 ± 0.64
1.982SerCys: 1.982 ± 0.68
4.46SerAsp: 4.46 ± 2.055
1.487SerGlu: 1.487 ± 0.667
3.469SerPhe: 3.469 ± 1.03
3.469SerGly: 3.469 ± 0.48
0.991SerHis: 0.991 ± 0.34
2.973SerIle: 2.973 ± 1.372
4.955SerLys: 4.955 ± 0.602
6.442SerLeu: 6.442 ± 0.398
1.487SerMet: 1.487 ± 0.328
3.469SerAsn: 3.469 ± 0.48
4.46SerPro: 4.46 ± 0.985
0.496SerGln: 0.496 ± 0.627
3.964SerArg: 3.964 ± 0.511
3.469SerSer: 3.469 ± 0.884
3.964SerThr: 3.964 ± 2.774
5.451SerVal: 5.451 ± 0.803
0.0SerTrp: 0.0 ± 0.0
0.991SerTyr: 0.991 ± 0.34
0.0SerXaa: 0.0 ± 0.0
Thr
3.964ThrAla: 3.964 ± 1.884
0.0ThrCys: 0.0 ± 0.0
0.991ThrAsp: 0.991 ± 0.34
2.478ThrGlu: 2.478 ± 0.231
2.973ThrPhe: 2.973 ± 1.372
3.964ThrGly: 3.964 ± 0.511
0.0ThrHis: 0.0 ± 0.0
3.469ThrIle: 3.469 ± 0.48
4.955ThrLys: 4.955 ± 1.588
2.478ThrLeu: 2.478 ± 1.35
0.496ThrMet: 0.496 ± 0.627
4.46ThrAsn: 4.46 ± 2.055
6.938ThrPro: 6.938 ± 0.64
0.496ThrGln: 0.496 ± 0.627
3.469ThrArg: 3.469 ± 0.918
1.487ThrSer: 1.487 ± 1.679
3.964ThrThr: 3.964 ± 0.455
3.469ThrVal: 3.469 ± 2.819
0.0ThrTrp: 0.0 ± 0.0
0.991ThrTyr: 0.991 ± 1.255
0.0ThrXaa: 0.0 ± 0.0
Val
6.442ValAla: 6.442 ± 1.399
2.478ValCys: 2.478 ± 0.231
4.955ValAsp: 4.955 ± 1.258
8.92ValGlu: 8.92 ± 1.598
3.469ValPhe: 3.469 ± 0.48
6.442ValGly: 6.442 ± 0.562
3.469ValHis: 3.469 ± 1.002
4.46ValIle: 4.46 ± 0.727
2.478ValLys: 2.478 ± 1.566
3.469ValLeu: 3.469 ± 1.03
0.991ValMet: 0.991 ± 0.34
5.946ValAsn: 5.946 ± 1.005
2.973ValPro: 2.973 ± 0.576
3.469ValGln: 3.469 ± 0.48
5.451ValArg: 5.451 ± 1.131
9.911ValSer: 9.911 ± 1.928
2.478ValThr: 2.478 ± 1.35
11.893ValVal: 11.893 ± 0.823
0.0ValTrp: 0.0 ± 0.0
1.487ValTyr: 1.487 ± 0.328
0.0ValXaa: 0.0 ± 0.0
Trp
0.496TrpAla: 0.496 ± 0.627
2.478TrpCys: 2.478 ± 0.231
0.0TrpAsp: 0.0 ± 0.0
0.991TrpGlu: 0.991 ± 0.34
0.0TrpPhe: 0.0 ± 0.0
0.991TrpGly: 0.991 ± 0.34
0.0TrpHis: 0.0 ± 0.0
0.991TrpIle: 0.991 ± 0.34
0.0TrpLys: 0.0 ± 0.0
1.982TrpLeu: 1.982 ± 0.68
0.0TrpMet: 0.0 ± 0.0
1.982TrpAsn: 1.982 ± 0.68
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.991TrpArg: 0.991 ± 0.34
1.982TrpSer: 1.982 ± 0.68
0.0TrpThr: 0.0 ± 0.0
1.487TrpVal: 1.487 ± 1.533
0.991TrpTrp: 0.991 ± 0.34
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.991TyrAla: 0.991 ± 0.34
0.0TyrCys: 0.0 ± 0.0
0.496TyrAsp: 0.496 ± 0.627
4.46TyrGlu: 4.46 ± 0.799
0.0TyrPhe: 0.0 ± 0.0
2.478TyrGly: 2.478 ± 0.231
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
0.991TyrLys: 0.991 ± 0.34
4.955TyrLeu: 4.955 ± 1.7
0.0TyrMet: 0.0 ± 0.0
1.487TyrAsn: 1.487 ± 0.686
0.0TyrPro: 0.0 ± 0.0
3.964TyrGln: 3.964 ± 1.36
1.982TyrArg: 1.982 ± 0.942
1.982TyrSer: 1.982 ± 0.868
2.973TyrThr: 2.973 ± 0.657
4.46TyrVal: 4.46 ± 0.799
0.0TyrTrp: 0.0 ± 0.0
0.496TyrTyr: 0.496 ± 0.814
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.991XaaGly: 0.991 ± 0.34
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2019 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski