Cottontail rabbit papillomavirus (strain Kansas) (CRPV) (Papillomavirus sylvilagi)

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Kappapapillomavirus; Kappapapillomavirus 2

Average proteome isoelectric point is 6.23

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 8 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P03130|VE7_CRPVK Protein E7 OS=Cottontail rabbit papillomavirus (strain Kansas) OX=31553 GN=E7 PE=3 SV=1
MM1 pKa = 7.5EE2 pKa = 5.02NCLPRR7 pKa = 11.84SLEE10 pKa = 3.82KK11 pKa = 10.61LQQILQISLEE21 pKa = 4.34DD22 pKa = 4.02LPFGCIFCGKK32 pKa = 10.03LLGAAEE38 pKa = 4.16KK39 pKa = 10.76QLFKK43 pKa = 10.79CTGLCIVWHH52 pKa = 6.4KK53 pKa = 9.79GWPYY57 pKa = 8.87GTCRR61 pKa = 11.84DD62 pKa = 4.11CTVLSCALDD71 pKa = 4.39LYY73 pKa = 11.12CHH75 pKa = 7.3LALTAPALEE84 pKa = 4.69AEE86 pKa = 4.33ALVGQEE92 pKa = 3.3ISSWFMRR99 pKa = 11.84CTVCGRR105 pKa = 11.84RR106 pKa = 11.84LTIPEE111 pKa = 4.5KK112 pKa = 10.52IEE114 pKa = 3.5LRR116 pKa = 11.84ARR118 pKa = 11.84NCTLCCIDD126 pKa = 4.05KK127 pKa = 10.68GQYY130 pKa = 7.9FQWRR134 pKa = 11.84GHH136 pKa = 6.16CSSCKK141 pKa = 10.4LSDD144 pKa = 3.24QGDD147 pKa = 3.7LGGYY151 pKa = 8.23PPSPGSRR158 pKa = 11.84CGEE161 pKa = 3.91CDD163 pKa = 3.34EE164 pKa = 5.23CCVPDD169 pKa = 4.23LTHH172 pKa = 6.64LTPVDD177 pKa = 4.08LEE179 pKa = 4.26EE180 pKa = 5.51LGLYY184 pKa = 8.44PGPEE188 pKa = 3.75GTYY191 pKa = 10.24PDD193 pKa = 5.08LVDD196 pKa = 5.1LGPGVFGEE204 pKa = 4.16EE205 pKa = 4.24DD206 pKa = 3.63EE207 pKa = 4.64EE208 pKa = 5.83GGGLFDD214 pKa = 5.0SFEE217 pKa = 4.45EE218 pKa = 4.26EE219 pKa = 4.6DD220 pKa = 4.45PGPNQCGCFFCTSYY234 pKa = 11.19PSGTGDD240 pKa = 3.15TDD242 pKa = 3.57INQGPAGAAGIALQSDD258 pKa = 4.13PVCFCEE264 pKa = 3.77NCINFTEE271 pKa = 4.7FRR273 pKa = 3.87

Molecular weight: 29.74 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P03125|VE5_CRPVK Probable protein E5 OS=Cottontail rabbit papillomavirus (strain Kansas) OX=31553 GN=E5 PE=3 SV=1
MM1 pKa = 7.28SHH3 pKa = 5.24GHH5 pKa = 5.86CRR7 pKa = 11.84IPVEE11 pKa = 4.48KK12 pKa = 10.44GSKK15 pKa = 9.77ALRR18 pKa = 11.84KK19 pKa = 8.71RR20 pKa = 11.84HH21 pKa = 5.27SKK23 pKa = 8.81RR24 pKa = 11.84TQLLLRR30 pKa = 11.84FTMMVTEE37 pKa = 4.58GTTMNTHH44 pKa = 6.43CGVYY48 pKa = 10.48LLLGTLMGSGLRR60 pKa = 11.84LKK62 pKa = 10.74VEE64 pKa = 3.72WTIEE68 pKa = 3.95GFIMWTLKK76 pKa = 9.61EE77 pKa = 4.5TMCIMWTSQPTRR89 pKa = 11.84DD90 pKa = 3.82VLLLMDD96 pKa = 4.06TMTWCFKK103 pKa = 9.96TCASLLLSPAPPSRR117 pKa = 11.84WSVPLKK123 pKa = 9.8TPSPKK128 pKa = 10.09RR129 pKa = 11.84PPTVQCPPLKK139 pKa = 10.13RR140 pKa = 11.84KK141 pKa = 9.52QGPKK145 pKa = 9.95PRR147 pKa = 11.84VHH149 pKa = 6.75WADD152 pKa = 3.41EE153 pKa = 4.55GQGHH157 pKa = 5.49QGCNEE162 pKa = 3.48GRR164 pKa = 11.84QSNEE168 pKa = 3.15NRR170 pKa = 11.84PPRR173 pKa = 11.84TKK175 pKa = 10.47RR176 pKa = 11.84ILLPGTSDD184 pKa = 3.73RR185 pKa = 11.84LLQRR189 pKa = 11.84TLDD192 pKa = 3.55EE193 pKa = 3.94EE194 pKa = 4.18LRR196 pKa = 11.84RR197 pKa = 11.84LEE199 pKa = 3.82EE200 pKa = 4.23HH201 pKa = 6.68LPGGIDD207 pKa = 3.73GFASLL212 pKa = 4.98

Molecular weight: 24.1 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8

0

8

2669

94

602

333.6

37.29

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.032 ± 0.63

2.698 ± 0.938

6.107 ± 0.528

6.145 ± 0.488

4.159 ± 0.373

6.744 ± 0.787

2.136 ± 0.263

3.784 ± 0.3

4.946 ± 0.719

9.816 ± 0.869

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.873 ± 0.405

3.634 ± 0.372

6.294 ± 0.619

4.871 ± 0.484

5.807 ± 0.56

7.981 ± 0.625

6.332 ± 0.499

6.22 ± 0.476

1.349 ± 0.268

3.072 ± 0.507
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski