Amino acid dipepetide frequency for Psittacus erithacus timneh papillomavirus (isolate African grey parrot) (PePV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.842AlaAla: 8.842 ± 3.54
0.402AlaCys: 0.402 ± 0.432
5.627AlaAsp: 5.627 ± 1.495
3.215AlaGlu: 3.215 ± 1.068
1.206AlaPhe: 1.206 ± 0.472
3.215AlaGly: 3.215 ± 0.749
0.0AlaHis: 0.0 ± 0.0
2.814AlaIle: 2.814 ± 0.709
1.206AlaLys: 1.206 ± 0.389
7.235AlaLeu: 7.235 ± 1.508
0.804AlaMet: 0.804 ± 0.804
1.206AlaAsn: 1.206 ± 0.654
4.421AlaPro: 4.421 ± 1.629
1.608AlaGln: 1.608 ± 0.642
4.019AlaArg: 4.019 ± 1.622
4.019AlaSer: 4.019 ± 1.248
5.627AlaThr: 5.627 ± 1.079
3.215AlaVal: 3.215 ± 0.766
0.402AlaTrp: 0.402 ± 0.297
2.814AlaTyr: 2.814 ± 0.866
0.0AlaXaa: 0.0 ± 0.0
Cys
0.804CysAla: 0.804 ± 0.711
0.804CysCys: 0.804 ± 0.5
0.402CysAsp: 0.402 ± 0.356
0.402CysGlu: 0.402 ± 0.297
1.206CysPhe: 1.206 ± 0.567
0.804CysGly: 0.804 ± 0.536
0.402CysHis: 0.402 ± 0.4
0.804CysIle: 0.804 ± 0.593
1.206CysLys: 1.206 ± 0.493
0.804CysLeu: 0.804 ± 0.518
0.402CysMet: 0.402 ± 0.356
0.804CysAsn: 0.804 ± 0.553
2.01CysPro: 2.01 ± 0.902
0.804CysGln: 0.804 ± 0.342
1.206CysArg: 1.206 ± 0.493
0.402CysSer: 0.402 ± 0.297
2.412CysThr: 2.412 ± 1.155
0.804CysVal: 0.804 ± 0.711
0.402CysTrp: 0.402 ± 0.356
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.814AspAla: 2.814 ± 0.853
1.608AspCys: 1.608 ± 0.573
7.235AspAsp: 7.235 ± 2.387
3.617AspGlu: 3.617 ± 1.142
2.01AspPhe: 2.01 ± 0.979
4.823AspGly: 4.823 ± 1.229
0.804AspHis: 0.804 ± 0.518
4.823AspIle: 4.823 ± 1.155
3.215AspLys: 3.215 ± 1.194
5.225AspLeu: 5.225 ± 1.31
1.206AspMet: 1.206 ± 0.753
2.814AspAsn: 2.814 ± 0.865
7.637AspPro: 7.637 ± 1.213
0.402AspGln: 0.402 ± 0.356
2.814AspArg: 2.814 ± 1.013
7.235AspSer: 7.235 ± 1.677
5.627AspThr: 5.627 ± 1.221
5.225AspVal: 5.225 ± 0.617
0.804AspTrp: 0.804 ± 0.355
1.206AspTyr: 1.206 ± 0.549
0.0AspXaa: 0.0 ± 0.0
Glu
3.215GluAla: 3.215 ± 1.281
0.0GluCys: 0.0 ± 0.0
3.617GluAsp: 3.617 ± 0.567
5.225GluGlu: 5.225 ± 1.417
0.402GluPhe: 0.402 ± 0.323
5.225GluGly: 5.225 ± 1.519
2.814GluHis: 2.814 ± 0.915
2.412GluIle: 2.412 ± 0.859
0.402GluLys: 0.402 ± 0.356
4.823GluLeu: 4.823 ± 1.014
0.804GluMet: 0.804 ± 0.647
1.608GluAsn: 1.608 ± 0.854
2.412GluPro: 2.412 ± 0.868
1.608GluGln: 1.608 ± 0.835
2.814GluArg: 2.814 ± 0.918
3.215GluSer: 3.215 ± 1.12
5.627GluThr: 5.627 ± 1.668
2.01GluVal: 2.01 ± 0.788
2.01GluTrp: 2.01 ± 0.743
2.814GluTyr: 2.814 ± 1.035
0.0GluXaa: 0.0 ± 0.0
Phe
0.804PheAla: 0.804 ± 0.473
0.0PheCys: 0.0 ± 0.0
1.608PheAsp: 1.608 ± 0.686
2.01PheGlu: 2.01 ± 0.916
1.206PhePhe: 1.206 ± 0.31
2.814PheGly: 2.814 ± 0.732
0.402PheHis: 0.402 ± 0.4
2.01PheIle: 2.01 ± 0.686
0.804PheLys: 0.804 ± 0.593
4.019PheLeu: 4.019 ± 0.876
1.206PheMet: 1.206 ± 0.89
2.412PheAsn: 2.412 ± 0.684
2.01PhePro: 2.01 ± 1.251
0.804PheGln: 0.804 ± 0.647
2.814PheArg: 2.814 ± 1.035
1.206PheSer: 1.206 ± 0.31
3.215PheThr: 3.215 ± 0.884
1.608PheVal: 1.608 ± 0.656
1.206PheTrp: 1.206 ± 0.31
0.804PheTyr: 0.804 ± 0.778
0.0PheXaa: 0.0 ± 0.0
Gly
4.823GlyAla: 4.823 ± 1.493
1.608GlyCys: 1.608 ± 0.709
6.833GlyAsp: 6.833 ± 1.522
4.421GlyGlu: 4.421 ± 1.483
1.206GlyPhe: 1.206 ± 0.549
8.441GlyGly: 8.441 ± 1.677
1.206GlyHis: 1.206 ± 0.726
6.431GlyIle: 6.431 ± 2.121
1.206GlyLys: 1.206 ± 0.646
4.823GlyLeu: 4.823 ± 1.335
1.206GlyMet: 1.206 ± 0.628
2.814GlyAsn: 2.814 ± 0.764
4.421GlyPro: 4.421 ± 1.37
4.421GlyGln: 4.421 ± 0.271
6.029GlyArg: 6.029 ± 0.622
3.215GlySer: 3.215 ± 0.7
6.029GlyThr: 6.029 ± 2.323
5.225GlyVal: 5.225 ± 1.877
0.804GlyTrp: 0.804 ± 0.342
2.01GlyTyr: 2.01 ± 1.177
0.0GlyXaa: 0.0 ± 0.0
His
2.01HisAla: 2.01 ± 0.943
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.206HisGlu: 1.206 ± 0.562
0.402HisPhe: 0.402 ± 0.297
2.412HisGly: 2.412 ± 1.279
0.402HisHis: 0.402 ± 0.297
0.804HisIle: 0.804 ± 0.518
1.206HisLys: 1.206 ± 0.726
2.412HisLeu: 2.412 ± 0.933
0.804HisMet: 0.804 ± 0.473
1.608HisAsn: 1.608 ± 0.807
0.0HisPro: 0.0 ± 0.0
0.804HisGln: 0.804 ± 0.553
0.804HisArg: 0.804 ± 0.593
1.608HisSer: 1.608 ± 0.442
1.206HisThr: 1.206 ± 0.6
3.215HisVal: 3.215 ± 1.089
0.804HisTrp: 0.804 ± 0.473
1.608HisTyr: 1.608 ± 0.939
0.0HisXaa: 0.0 ± 0.0
Ile
2.412IleAla: 2.412 ± 0.774
0.804IleCys: 0.804 ± 0.474
3.617IleAsp: 3.617 ± 1.417
1.608IleGlu: 1.608 ± 0.442
0.402IlePhe: 0.402 ± 0.297
4.019IleGly: 4.019 ± 0.91
0.402IleHis: 0.402 ± 0.297
3.215IleIle: 3.215 ± 1.011
0.402IleLys: 0.402 ± 0.432
4.421IleLeu: 4.421 ± 2.207
0.804IleMet: 0.804 ± 0.553
1.608IleAsn: 1.608 ± 0.505
4.823IlePro: 4.823 ± 0.724
1.608IleGln: 1.608 ± 0.818
3.617IleArg: 3.617 ± 1.255
6.833IleSer: 6.833 ± 1.811
2.814IleThr: 2.814 ± 0.829
3.215IleVal: 3.215 ± 0.83
1.206IleTrp: 1.206 ± 0.847
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.804LysAla: 0.804 ± 0.711
1.206LysCys: 1.206 ± 0.474
2.412LysAsp: 2.412 ± 0.78
0.804LysGlu: 0.804 ± 0.593
1.608LysPhe: 1.608 ± 0.623
1.608LysGly: 1.608 ± 0.623
1.206LysHis: 1.206 ± 0.89
0.804LysIle: 0.804 ± 0.49
0.804LysLys: 0.804 ± 0.41
1.608LysLeu: 1.608 ± 0.642
0.402LysMet: 0.402 ± 0.297
0.402LysAsn: 0.402 ± 0.297
1.206LysPro: 1.206 ± 0.646
2.01LysGln: 2.01 ± 0.728
4.421LysArg: 4.421 ± 1.577
1.608LysSer: 1.608 ± 1.186
2.412LysThr: 2.412 ± 1.185
1.206LysVal: 1.206 ± 0.741
0.0LysTrp: 0.0 ± 0.0
2.01LysTyr: 2.01 ± 0.743
0.0LysXaa: 0.0 ± 0.0
Leu
3.617LeuAla: 3.617 ± 0.812
1.608LeuCys: 1.608 ± 0.658
6.431LeuAsp: 6.431 ± 0.777
3.215LeuGlu: 3.215 ± 0.958
4.421LeuPhe: 4.421 ± 1.357
6.029LeuGly: 6.029 ± 0.995
1.608LeuHis: 1.608 ± 0.484
4.019LeuIle: 4.019 ± 1.367
3.617LeuLys: 3.617 ± 1.245
9.646LeuLeu: 9.646 ± 2.35
2.01LeuMet: 2.01 ± 0.81
2.412LeuAsn: 2.412 ± 0.593
5.627LeuPro: 5.627 ± 1.997
6.833LeuGln: 6.833 ± 1.655
5.225LeuArg: 5.225 ± 1.628
8.039LeuSer: 8.039 ± 1.043
2.01LeuThr: 2.01 ± 0.839
3.215LeuVal: 3.215 ± 0.67
0.804LeuTrp: 0.804 ± 0.342
3.215LeuTyr: 3.215 ± 1.337
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
1.608MetCys: 1.608 ± 0.686
2.01MetAsp: 2.01 ± 0.491
3.215MetGlu: 3.215 ± 1.664
0.402MetPhe: 0.402 ± 0.297
0.0MetGly: 0.0 ± 0.0
0.402MetHis: 0.402 ± 0.356
1.608MetIle: 1.608 ± 0.82
0.402MetLys: 0.402 ± 0.432
0.804MetLeu: 0.804 ± 0.355
0.0MetMet: 0.0 ± 0.0
0.402MetAsn: 0.402 ± 0.356
0.0MetPro: 0.0 ± 0.0
0.804MetGln: 0.804 ± 0.474
2.01MetArg: 2.01 ± 0.879
1.206MetSer: 1.206 ± 0.549
0.402MetThr: 0.402 ± 0.356
2.412MetVal: 2.412 ± 0.438
0.402MetTrp: 0.402 ± 0.356
0.402MetTyr: 0.402 ± 0.297
0.0MetXaa: 0.0 ± 0.0
Asn
1.608AsnAla: 1.608 ± 0.642
0.804AsnCys: 0.804 ± 0.5
2.814AsnAsp: 2.814 ± 0.771
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
2.01AsnGly: 2.01 ± 0.732
0.804AsnHis: 0.804 ± 0.474
2.01AsnIle: 2.01 ± 0.321
1.608AsnLys: 1.608 ± 0.613
1.206AsnLeu: 1.206 ± 0.653
0.402AsnMet: 0.402 ± 0.297
1.206AsnAsn: 1.206 ± 0.646
3.215AsnPro: 3.215 ± 0.761
1.206AsnGln: 1.206 ± 0.741
2.412AsnArg: 2.412 ± 0.725
3.617AsnSer: 3.617 ± 1.059
3.617AsnThr: 3.617 ± 1.625
2.412AsnVal: 2.412 ± 1.048
0.0AsnTrp: 0.0 ± 0.0
2.01AsnTyr: 2.01 ± 0.784
0.0AsnXaa: 0.0 ± 0.0
Pro
6.431ProAla: 6.431 ± 1.8
0.804ProCys: 0.804 ± 0.355
6.431ProAsp: 6.431 ± 1.769
4.019ProGlu: 4.019 ± 1.238
2.412ProPhe: 2.412 ± 1.94
2.814ProGly: 2.814 ± 0.652
2.814ProHis: 2.814 ± 0.874
2.01ProIle: 2.01 ± 0.506
2.814ProLys: 2.814 ± 1.217
6.833ProLeu: 6.833 ± 2.022
0.0ProMet: 0.0 ± 0.0
3.215ProAsn: 3.215 ± 0.688
7.637ProPro: 7.637 ± 2.213
1.608ProGln: 1.608 ± 0.475
4.421ProArg: 4.421 ± 0.902
4.421ProSer: 4.421 ± 1.49
7.235ProThr: 7.235 ± 1.707
6.029ProVal: 6.029 ± 2.839
1.206ProTrp: 1.206 ± 0.83
3.617ProTyr: 3.617 ± 0.678
0.0ProXaa: 0.0 ± 0.0
Gln
1.608GlnAla: 1.608 ± 0.709
0.804GlnCys: 0.804 ± 0.355
2.412GlnAsp: 2.412 ± 0.898
2.814GlnGlu: 2.814 ± 1.435
0.804GlnPhe: 0.804 ± 0.355
1.608GlnGly: 1.608 ± 0.954
2.412GlnHis: 2.412 ± 0.771
0.804GlnIle: 0.804 ± 0.342
1.206GlnLys: 1.206 ± 0.563
4.823GlnLeu: 4.823 ± 0.97
0.804GlnMet: 0.804 ± 0.355
0.804GlnAsn: 0.804 ± 0.415
2.814GlnPro: 2.814 ± 0.798
0.402GlnGln: 0.402 ± 0.4
2.814GlnArg: 2.814 ± 1.062
0.804GlnSer: 0.804 ± 0.474
2.01GlnThr: 2.01 ± 0.729
2.814GlnVal: 2.814 ± 0.797
1.206GlnTrp: 1.206 ± 0.552
1.206GlnTyr: 1.206 ± 0.31
0.0GlnXaa: 0.0 ± 0.0
Arg
2.814ArgAla: 2.814 ± 0.502
1.608ArgCys: 1.608 ± 0.642
2.412ArgAsp: 2.412 ± 1.065
4.019ArgGlu: 4.019 ± 0.962
2.412ArgPhe: 2.412 ± 0.562
5.627ArgGly: 5.627 ± 1.075
1.608ArgHis: 1.608 ± 0.686
2.814ArgIle: 2.814 ± 0.557
2.01ArgLys: 2.01 ± 0.506
8.842ArgLeu: 8.842 ± 2.775
2.814ArgMet: 2.814 ± 0.762
1.206ArgAsn: 1.206 ± 0.726
5.627ArgPro: 5.627 ± 1.399
2.01ArgGln: 2.01 ± 0.855
11.656ArgArg: 11.656 ± 2.965
5.225ArgSer: 5.225 ± 1.05
6.029ArgThr: 6.029 ± 1.826
5.225ArgVal: 5.225 ± 2.421
0.402ArgTrp: 0.402 ± 0.356
3.215ArgTyr: 3.215 ± 0.518
0.0ArgXaa: 0.0 ± 0.0
Ser
8.039SerAla: 8.039 ± 2.155
0.402SerCys: 0.402 ± 0.356
5.627SerAsp: 5.627 ± 0.864
4.019SerGlu: 4.019 ± 0.601
3.215SerPhe: 3.215 ± 0.934
7.235SerGly: 7.235 ± 0.967
2.412SerHis: 2.412 ± 1.185
2.412SerIle: 2.412 ± 0.949
2.01SerLys: 2.01 ± 0.875
4.019SerLeu: 4.019 ± 1.698
1.206SerMet: 1.206 ± 0.474
3.617SerAsn: 3.617 ± 1.092
6.029SerPro: 6.029 ± 0.675
2.01SerGln: 2.01 ± 1.086
3.617SerArg: 3.617 ± 0.763
5.225SerSer: 5.225 ± 2.201
6.029SerThr: 6.029 ± 1.508
4.019SerVal: 4.019 ± 1.369
0.0SerTrp: 0.0 ± 0.0
2.01SerTyr: 2.01 ± 0.618
0.0SerXaa: 0.0 ± 0.0
Thr
6.029ThrAla: 6.029 ± 1.218
0.0ThrCys: 0.0 ± 0.0
4.019ThrAsp: 4.019 ± 1.328
4.421ThrGlu: 4.421 ± 1.803
4.421ThrPhe: 4.421 ± 1.111
6.029ThrGly: 6.029 ± 1.439
1.206ThrHis: 1.206 ± 0.683
5.225ThrIle: 5.225 ± 1.414
1.206ThrLys: 1.206 ± 0.31
3.215ThrLeu: 3.215 ± 1.081
0.804ThrMet: 0.804 ± 0.474
2.01ThrAsn: 2.01 ± 0.506
6.833ThrPro: 6.833 ± 1.323
2.412ThrGln: 2.412 ± 0.634
7.637ThrArg: 7.637 ± 1.404
5.627ThrSer: 5.627 ± 1.221
4.823ThrThr: 4.823 ± 1.375
6.029ThrVal: 6.029 ± 0.906
1.608ThrTrp: 1.608 ± 1.112
1.206ThrTyr: 1.206 ± 0.497
0.0ThrXaa: 0.0 ± 0.0
Val
1.608ValAla: 1.608 ± 0.406
2.01ValCys: 2.01 ± 0.993
4.019ValAsp: 4.019 ± 1.132
2.814ValGlu: 2.814 ± 1.24
3.215ValPhe: 3.215 ± 0.649
6.833ValGly: 6.833 ± 1.21
0.402ValHis: 0.402 ± 0.297
1.206ValIle: 1.206 ± 0.552
0.804ValLys: 0.804 ± 0.41
5.225ValLeu: 5.225 ± 1.324
0.804ValMet: 0.804 ± 0.355
1.608ValAsn: 1.608 ± 0.406
6.431ValPro: 6.431 ± 2.263
2.01ValGln: 2.01 ± 0.732
4.823ValArg: 4.823 ± 1.234
8.842ValSer: 8.842 ± 1.389
4.019ValThr: 4.019 ± 1.086
4.019ValVal: 4.019 ± 1.792
0.402ValTrp: 0.402 ± 0.356
3.617ValTyr: 3.617 ± 1.005
0.0ValXaa: 0.0 ± 0.0
Trp
0.804TrpAla: 0.804 ± 0.355
0.0TrpCys: 0.0 ± 0.0
1.206TrpAsp: 1.206 ± 0.387
0.804TrpGlu: 0.804 ± 0.778
0.402TrpPhe: 0.402 ± 0.323
2.412TrpGly: 2.412 ± 1.0
0.804TrpHis: 0.804 ± 0.778
1.206TrpIle: 1.206 ± 0.389
0.804TrpLys: 0.804 ± 0.474
1.206TrpLeu: 1.206 ± 0.549
0.402TrpMet: 0.402 ± 0.297
0.402TrpAsn: 0.402 ± 0.4
0.402TrpPro: 0.402 ± 0.297
1.206TrpGln: 1.206 ± 0.753
1.206TrpArg: 1.206 ± 0.387
0.402TrpSer: 0.402 ± 0.389
0.804TrpThr: 0.804 ± 0.473
0.804TrpVal: 0.804 ± 0.342
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.814TyrAla: 2.814 ± 0.668
0.804TyrCys: 0.804 ± 0.553
2.412TyrAsp: 2.412 ± 0.754
1.206TyrGlu: 1.206 ± 0.549
1.608TyrPhe: 1.608 ± 0.403
3.215TyrGly: 3.215 ± 0.766
1.206TyrHis: 1.206 ± 0.567
0.804TyrIle: 0.804 ± 0.711
1.608TyrLys: 1.608 ± 0.693
2.412TyrLeu: 2.412 ± 0.72
1.206TyrMet: 1.206 ± 0.549
0.804TyrAsn: 0.804 ± 0.41
3.215TyrPro: 3.215 ± 1.122
0.402TyrGln: 0.402 ± 0.297
3.215TyrArg: 3.215 ± 0.662
0.402TyrSer: 0.402 ± 0.4
2.814TyrThr: 2.814 ± 0.857
2.01TyrVal: 2.01 ± 0.979
1.608TyrTrp: 1.608 ± 0.693
1.206TyrTyr: 1.206 ± 0.596
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2489 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski