Amino acid dipepetide frequency for Arsenicibacter rosenii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.673AlaAla: 7.673 ± 0.089	0.812AlaCys: 0.812 ± 0.023	5.098AlaAsp: 5.098 ± 0.058	4.646AlaGlu: 4.646 ± 0.058	3.839AlaPhe: 3.839 ± 0.041	7.58AlaGly: 7.58 ± 0.076	1.335AlaHis: 1.335 ± 0.03	5.057AlaIle: 5.057 ± 0.059	3.745AlaLys: 3.745 ± 0.052	8.064AlaLeu: 8.064 ± 0.072	1.941AlaMet: 1.941 ± 0.029	3.829AlaAsn: 3.829 ± 0.049	3.328AlaPro: 3.328 ± 0.046	3.62AlaGln: 3.62 ± 0.047	4.178AlaArg: 4.178 ± 0.044	5.042AlaSer: 5.042 ± 0.06	5.492AlaThr: 5.492 ± 0.072	5.86AlaVal: 5.86 ± 0.058	1.07AlaTrp: 1.07 ± 0.022	3.184AlaTyr: 3.184 ± 0.037	0.003AlaXaa: 0.003 ± 0.001
Cys	0.551CysAla: 0.551 ± 0.017	0.116CysCys: 0.116 ± 0.007	0.427CysAsp: 0.427 ± 0.027	0.361CysGlu: 0.361 ± 0.013	0.372CysPhe: 0.372 ± 0.014	0.601CysGly: 0.601 ± 0.022	0.215CysHis: 0.215 ± 0.011	0.48CysIle: 0.48 ± 0.015	0.296CysLys: 0.296 ± 0.013	0.902CysLeu: 0.902 ± 0.021	0.156CysMet: 0.156 ± 0.008	0.302CysAsn: 0.302 ± 0.013	0.395CysPro: 0.395 ± 0.016	0.379CysGln: 0.379 ± 0.015	0.469CysArg: 0.469 ± 0.017	0.548CysSer: 0.548 ± 0.022	0.534CysThr: 0.534 ± 0.022	0.498CysVal: 0.498 ± 0.016	0.122CysTrp: 0.122 ± 0.008	0.307CysTyr: 0.307 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.283AspAla: 4.283 ± 0.046	0.389AspCys: 0.389 ± 0.013	2.642AspAsp: 2.642 ± 0.039	3.251AspGlu: 3.251 ± 0.043	2.637AspPhe: 2.637 ± 0.036	4.204AspGly: 4.204 ± 0.053	0.952AspHis: 0.952 ± 0.022	3.201AspIle: 3.201 ± 0.049	2.856AspLys: 2.856 ± 0.043	4.999AspLeu: 4.999 ± 0.057	1.188AspMet: 1.188 ± 0.023	2.364AspAsn: 2.364 ± 0.038	2.603AspPro: 2.603 ± 0.042	2.182AspGln: 2.182 ± 0.035	2.948AspArg: 2.948 ± 0.041	2.654AspSer: 2.654 ± 0.035	2.753AspThr: 2.753 ± 0.045	3.611AspVal: 3.611 ± 0.038	0.924AspTrp: 0.924 ± 0.023	2.251AspTyr: 2.251 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	4.81GluAla: 4.81 ± 0.059	0.275GluCys: 0.275 ± 0.013	2.133GluAsp: 2.133 ± 0.035	2.927GluGlu: 2.927 ± 0.051	1.941GluPhe: 1.941 ± 0.035	3.274GluGly: 3.274 ± 0.044	1.016GluHis: 1.016 ± 0.024	3.049GluIle: 3.049 ± 0.042	3.324GluLys: 3.324 ± 0.05	5.346GluLeu: 5.346 ± 0.06	1.226GluMet: 1.226 ± 0.028	2.313GluAsn: 2.313 ± 0.036	2.046GluPro: 2.046 ± 0.036	2.69GluGln: 2.69 ± 0.042	3.016GluArg: 3.016 ± 0.043	2.666GluSer: 2.666 ± 0.034	3.152GluThr: 3.152 ± 0.043	3.467GluVal: 3.467 ± 0.04	0.682GluTrp: 0.682 ± 0.019	1.777GluTyr: 1.777 ± 0.03	0.0GluXaa: 0.0 ± 0.001
Phe	3.418PheAla: 3.418 ± 0.039	0.418PheCys: 0.418 ± 0.014	2.854PheAsp: 2.854 ± 0.038	2.084PheGlu: 2.084 ± 0.031	2.164PhePhe: 2.164 ± 0.04	3.451PheGly: 3.451 ± 0.043	0.734PheHis: 0.734 ± 0.02	2.488PheIle: 2.488 ± 0.036	1.854PheLys: 1.854 ± 0.033	4.052PheLeu: 4.052 ± 0.05	1.068PheMet: 1.068 ± 0.024	2.123PheAsn: 2.123 ± 0.036	1.838PhePro: 1.838 ± 0.03	1.509PheGln: 1.509 ± 0.027	2.651PheArg: 2.651 ± 0.042	3.309PheSer: 3.309 ± 0.039	3.207PheThr: 3.207 ± 0.044	2.967PheVal: 2.967 ± 0.042	0.633PheTrp: 0.633 ± 0.016	1.795PheTyr: 1.795 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.321GlyAla: 5.321 ± 0.065	0.795GlyCys: 0.795 ± 0.027	3.413GlyAsp: 3.413 ± 0.046	3.334GlyGlu: 3.334 ± 0.04	3.6GlyPhe: 3.6 ± 0.042	5.539GlyGly: 5.539 ± 0.08	1.304GlyHis: 1.304 ± 0.023	4.884GlyIle: 4.884 ± 0.043	4.42GlyLys: 4.42 ± 0.057	7.176GlyLeu: 7.176 ± 0.067	1.808GlyMet: 1.808 ± 0.033	3.565GlyAsn: 3.565 ± 0.057	2.306GlyPro: 2.306 ± 0.038	3.509GlyGln: 3.509 ± 0.044	3.701GlyArg: 3.701 ± 0.049	4.801GlySer: 4.801 ± 0.068	5.128GlyThr: 5.128 ± 0.075	4.973GlyVal: 4.973 ± 0.056	1.195GlyTrp: 1.195 ± 0.027	3.126GlyTyr: 3.126 ± 0.037	0.001GlyXaa: 0.001 ± 0.001
His	1.268HisAla: 1.268 ± 0.022	0.174HisCys: 0.174 ± 0.01	0.931HisAsp: 0.931 ± 0.022	0.967HisGlu: 0.967 ± 0.019	0.987HisPhe: 0.987 ± 0.023	1.189HisGly: 1.189 ± 0.025	0.491HisHis: 0.491 ± 0.018	1.214HisIle: 1.214 ± 0.028	0.803HisLys: 0.803 ± 0.018	1.873HisLeu: 1.873 ± 0.034	0.357HisMet: 0.357 ± 0.014	0.75HisAsn: 0.75 ± 0.02	1.136HisPro: 1.136 ± 0.024	0.833HisGln: 0.833 ± 0.025	1.031HisArg: 1.031 ± 0.025	0.956HisSer: 0.956 ± 0.021	1.137HisThr: 1.137 ± 0.02	1.099HisVal: 1.099 ± 0.028	0.306HisTrp: 0.306 ± 0.014	0.831HisTyr: 0.831 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	4.967IleAla: 4.967 ± 0.06	0.574IleCys: 0.574 ± 0.019	3.787IleAsp: 3.787 ± 0.046	3.155IleGlu: 3.155 ± 0.042	2.045IlePhe: 2.045 ± 0.035	4.604IleGly: 4.604 ± 0.053	1.119IleHis: 1.119 ± 0.023	3.152IleIle: 3.152 ± 0.048	2.721IleLys: 2.721 ± 0.04	4.904IleLeu: 4.904 ± 0.054	1.096IleMet: 1.096 ± 0.022	3.007IleAsn: 3.007 ± 0.035	2.939IlePro: 2.939 ± 0.041	2.391IleGln: 2.391 ± 0.034	3.807IleArg: 3.807 ± 0.046	3.85IleSer: 3.85 ± 0.044	3.973IleThr: 3.973 ± 0.049	3.636IleVal: 3.636 ± 0.046	0.707IleTrp: 0.707 ± 0.018	2.038IleTyr: 2.038 ± 0.03	0.001IleXaa: 0.001 ± 0.001
Lys	4.852LysAla: 4.852 ± 0.064	0.205LysCys: 0.205 ± 0.01	2.612LysAsp: 2.612 ± 0.042	2.959LysGlu: 2.959 ± 0.048	1.51LysPhe: 1.51 ± 0.028	3.615LysGly: 3.615 ± 0.045	0.929LysHis: 0.929 ± 0.023	2.769LysIle: 2.769 ± 0.039	3.126LysLys: 3.126 ± 0.055	4.647LysLeu: 4.647 ± 0.054	1.233LysMet: 1.233 ± 0.026	2.403LysAsn: 2.403 ± 0.043	2.907LysPro: 2.907 ± 0.044	2.383LysGln: 2.383 ± 0.033	2.624LysArg: 2.624 ± 0.041	2.68LysSer: 2.68 ± 0.04	3.37LysThr: 3.37 ± 0.046	3.146LysVal: 3.146 ± 0.04	0.601LysTrp: 0.601 ± 0.018	1.754LysTyr: 1.754 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	8.51LeuAla: 8.51 ± 0.075	0.81LeuCys: 0.81 ± 0.023	4.717LeuAsp: 4.717 ± 0.056	4.397LeuGlu: 4.397 ± 0.058	4.478LeuPhe: 4.478 ± 0.051	5.984LeuGly: 5.984 ± 0.06	1.834LeuHis: 1.834 ± 0.034	5.757LeuIle: 5.757 ± 0.064	5.21LeuLys: 5.21 ± 0.053	10.166LeuLeu: 10.166 ± 0.107	2.264LeuMet: 2.264 ± 0.038	4.654LeuAsn: 4.654 ± 0.055	5.094LeuPro: 5.094 ± 0.059	3.771LeuGln: 3.771 ± 0.047	5.117LeuArg: 5.117 ± 0.056	6.836LeuSer: 6.836 ± 0.065	7.647LeuThr: 7.647 ± 0.081	6.091LeuVal: 6.091 ± 0.057	1.118LeuTrp: 1.118 ± 0.026	3.349LeuTyr: 3.349 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	2.185MetAla: 2.185 ± 0.035	0.125MetCys: 0.125 ± 0.008	1.065MetAsp: 1.065 ± 0.022	1.059MetGlu: 1.059 ± 0.028	0.697MetPhe: 0.697 ± 0.019	1.517MetGly: 1.517 ± 0.029	0.454MetHis: 0.454 ± 0.015	1.2MetIle: 1.2 ± 0.032	1.479MetLys: 1.479 ± 0.029	2.285MetLeu: 2.285 ± 0.036	0.574MetMet: 0.574 ± 0.018	1.073MetAsn: 1.073 ± 0.023	1.223MetPro: 1.223 ± 0.026	1.049MetGln: 1.049 ± 0.025	1.13MetArg: 1.13 ± 0.024	1.287MetSer: 1.287 ± 0.024	1.49MetThr: 1.49 ± 0.026	1.353MetVal: 1.353 ± 0.029	0.207MetTrp: 0.207 ± 0.009	0.642MetTyr: 0.642 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.801AsnAla: 3.801 ± 0.048	0.363AsnCys: 0.363 ± 0.015	2.349AsnAsp: 2.349 ± 0.041	2.229AsnGlu: 2.229 ± 0.031	1.818AsnPhe: 1.818 ± 0.031	3.954AsnGly: 3.954 ± 0.055	0.863AsnHis: 0.863 ± 0.024	2.499AsnIle: 2.499 ± 0.038	2.084AsnLys: 2.084 ± 0.033	4.293AsnLeu: 4.293 ± 0.047	0.942AsnMet: 0.942 ± 0.02	2.325AsnAsn: 2.325 ± 0.042	2.854AsnPro: 2.854 ± 0.045	2.162AsnGln: 2.162 ± 0.037	2.816AsnArg: 2.816 ± 0.037	2.564AsnSer: 2.564 ± 0.049	3.026AsnThr: 3.026 ± 0.052	2.959AsnVal: 2.959 ± 0.053	0.675AsnTrp: 0.675 ± 0.021	1.95AsnTyr: 1.95 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	5.359ProAla: 5.359 ± 0.067	0.274ProCys: 0.274 ± 0.012	3.462ProAsp: 3.462 ± 0.041	3.12ProGlu: 3.12 ± 0.043	2.103ProPhe: 2.103 ± 0.031	3.439ProGly: 3.439 ± 0.052	0.783ProHis: 0.783 ± 0.018	2.084ProIle: 2.084 ± 0.034	2.177ProLys: 2.177 ± 0.033	3.866ProLeu: 3.866 ± 0.046	0.957ProMet: 0.957 ± 0.022	2.125ProAsn: 2.125 ± 0.033	1.528ProPro: 1.528 ± 0.036	1.658ProGln: 1.658 ± 0.033	1.579ProArg: 1.579 ± 0.026	2.388ProSer: 2.388 ± 0.034	2.656ProThr: 2.656 ± 0.045	4.644ProVal: 4.644 ± 0.054	0.488ProTrp: 0.488 ± 0.015	1.671ProTyr: 1.671 ± 0.032	0.001ProXaa: 0.001 ± 0.001
Gln	3.885GlnAla: 3.885 ± 0.05	0.241GlnCys: 0.241 ± 0.012	1.765GlnAsp: 1.765 ± 0.028	2.161GlnGlu: 2.161 ± 0.038	1.786GlnPhe: 1.786 ± 0.03	2.539GlnGly: 2.539 ± 0.045	0.919GlnHis: 0.919 ± 0.025	2.541GlnIle: 2.541 ± 0.038	2.377GlnLys: 2.377 ± 0.035	4.733GlnLeu: 4.733 ± 0.052	0.89GlnMet: 0.89 ± 0.023	1.896GlnAsn: 1.896 ± 0.032	2.314GlnPro: 2.314 ± 0.038	2.702GlnGln: 2.702 ± 0.047	2.309GlnArg: 2.309 ± 0.036	2.433GlnSer: 2.433 ± 0.034	3.148GlnThr: 3.148 ± 0.041	2.883GlnVal: 2.883 ± 0.038	0.575GlnTrp: 0.575 ± 0.018	1.702GlnTyr: 1.702 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	3.537ArgAla: 3.537 ± 0.046	0.326ArgCys: 0.326 ± 0.013	2.509ArgAsp: 2.509 ± 0.034	2.875ArgGlu: 2.875 ± 0.043	2.823ArgPhe: 2.823 ± 0.043	2.799ArgGly: 2.799 ± 0.041	1.065ArgHis: 1.065 ± 0.024	3.728ArgIle: 3.728 ± 0.048	2.967ArgLys: 2.967 ± 0.04	5.641ArgLeu: 5.641 ± 0.06	1.375ArgMet: 1.375 ± 0.025	2.575ArgAsn: 2.575 ± 0.037	2.31ArgPro: 2.31 ± 0.036	3.063ArgGln: 3.063 ± 0.048	2.835ArgArg: 2.835 ± 0.047	2.891ArgSer: 2.891 ± 0.039	3.129ArgThr: 3.129 ± 0.038	3.311ArgVal: 3.311 ± 0.043	0.83ArgTrp: 0.83 ± 0.021	2.414ArgTyr: 2.414 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.249SerAla: 5.249 ± 0.062	0.518SerCys: 0.518 ± 0.018	2.984SerAsp: 2.984 ± 0.037	2.699SerGlu: 2.699 ± 0.036	3.209SerPhe: 3.209 ± 0.04	5.366SerGly: 5.366 ± 0.069	1.021SerHis: 1.021 ± 0.024	3.411SerIle: 3.411 ± 0.044	2.47SerLys: 2.47 ± 0.038	6.44SerLeu: 6.44 ± 0.063	1.206SerMet: 1.206 ± 0.022	2.412SerAsn: 2.412 ± 0.043	2.88SerPro: 2.88 ± 0.045	2.275SerGln: 2.275 ± 0.037	2.973SerArg: 2.973 ± 0.041	3.634SerSer: 3.634 ± 0.059	3.716SerThr: 3.716 ± 0.063	4.793SerVal: 4.793 ± 0.063	0.808SerTrp: 0.808 ± 0.023	2.427SerTyr: 2.427 ± 0.037	0.001SerXaa: 0.001 ± 0.001
Thr	5.992ThrAla: 5.992 ± 0.09	0.475ThrCys: 0.475 ± 0.02	3.788ThrAsp: 3.788 ± 0.049	3.057ThrGlu: 3.057 ± 0.041	3.007ThrPhe: 3.007 ± 0.041	6.079ThrGly: 6.079 ± 0.071	1.078ThrHis: 1.078 ± 0.024	4.12ThrIle: 4.12 ± 0.048	2.613ThrLys: 2.613 ± 0.034	6.494ThrLeu: 6.494 ± 0.069	1.143ThrMet: 1.143 ± 0.023	2.997ThrAsn: 2.997 ± 0.057	3.426ThrPro: 3.426 ± 0.048	2.255ThrGln: 2.255 ± 0.038	2.905ThrArg: 2.905 ± 0.04	3.709ThrSer: 3.709 ± 0.056	4.404ThrThr: 4.404 ± 0.075	5.038ThrVal: 5.038 ± 0.08	0.795ThrTrp: 0.795 ± 0.025	2.661ThrTyr: 2.661 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	5.742ValAla: 5.742 ± 0.061	0.697ValCys: 0.697 ± 0.021	3.526ValAsp: 3.526 ± 0.046	3.249ValGlu: 3.249 ± 0.041	3.092ValPhe: 3.092 ± 0.042	4.473ValGly: 4.473 ± 0.053	1.098ValHis: 1.098 ± 0.023	4.176ValIle: 4.176 ± 0.052	3.365ValLys: 3.365 ± 0.053	6.609ValLeu: 6.609 ± 0.07	1.587ValMet: 1.587 ± 0.034	3.259ValAsn: 3.259 ± 0.045	3.018ValPro: 3.018 ± 0.038	2.664ValGln: 2.664 ± 0.033	3.704ValArg: 3.704 ± 0.049	5.1ValSer: 5.1 ± 0.056	4.689ValThr: 4.689 ± 0.071	5.063ValVal: 5.063 ± 0.069	0.934ValTrp: 0.934 ± 0.021	2.601ValTyr: 2.601 ± 0.037	0.001ValXaa: 0.001 ± 0.001
Trp	0.947TrpAla: 0.947 ± 0.024	0.109TrpCys: 0.109 ± 0.007	0.642TrpAsp: 0.642 ± 0.019	0.646TrpGlu: 0.646 ± 0.017	0.621TrpPhe: 0.621 ± 0.016	0.933TrpGly: 0.933 ± 0.025	0.329TrpHis: 0.329 ± 0.013	0.712TrpIle: 0.712 ± 0.021	0.67TrpLys: 0.67 ± 0.019	1.579TrpLeu: 1.579 ± 0.029	0.363TrpMet: 0.363 ± 0.014	0.643TrpAsn: 0.643 ± 0.02	0.474TrpPro: 0.474 ± 0.016	0.839TrpGln: 0.839 ± 0.023	0.705TrpArg: 0.705 ± 0.021	0.815TrpSer: 0.815 ± 0.022	0.756TrpThr: 0.756 ± 0.021	0.894TrpVal: 0.894 ± 0.022	0.242TrpTrp: 0.242 ± 0.012	0.534TrpTyr: 0.534 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.046TyrAla: 3.046 ± 0.039	0.336TyrCys: 0.336 ± 0.015	2.184TyrAsp: 2.184 ± 0.033	1.956TyrGlu: 1.956 ± 0.027	1.89TyrPhe: 1.89 ± 0.029	2.757TyrGly: 2.757 ± 0.036	0.794TyrHis: 0.794 ± 0.021	1.95TyrIle: 1.95 ± 0.03	1.769TyrLys: 1.769 ± 0.031	3.735TyrLeu: 3.735 ± 0.043	0.717TyrMet: 0.717 ± 0.017	1.914TyrAsn: 1.914 ± 0.036	1.743TyrPro: 1.743 ± 0.033	1.864TyrGln: 1.864 ± 0.034	2.501TyrArg: 2.501 ± 0.038	2.33TyrSer: 2.33 ± 0.039	2.631TyrThr: 2.631 ± 0.049	2.357TyrVal: 2.357 ± 0.033	0.54TyrTrp: 0.54 ± 0.017	1.66TyrTyr: 1.66 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.001XaaHis: 0.001 ± 0.001	0.0XaaIle: 0.0 ± 0.001	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.001XaaMet: 0.001 ± 0.001	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.002XaaThr: 0.002 ± 0.001	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.001

Statistics based on 5902 proteins (2137068 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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