Amino acid dipepetide frequency for Moraxella macacae 0408225

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.677AlaAla: 3.677 ± 0.119
1.108AlaCys: 1.108 ± 0.05
4.872AlaAsp: 4.872 ± 0.094
3.827AlaGlu: 3.827 ± 0.096
3.262AlaPhe: 3.262 ± 0.07
5.652AlaGly: 5.652 ± 0.116
1.562AlaHis: 1.562 ± 0.054
5.959AlaIle: 5.959 ± 0.119
7.219AlaLys: 7.219 ± 0.115
9.085AlaLeu: 9.085 ± 0.147
2.692AlaMet: 2.692 ± 0.071
5.101AlaAsn: 5.101 ± 0.103
2.462AlaPro: 2.462 ± 0.071
3.529AlaGln: 3.529 ± 0.092
2.903AlaArg: 2.903 ± 0.074
4.882AlaSer: 4.882 ± 0.101
5.128AlaThr: 5.128 ± 0.096
5.911AlaVal: 5.911 ± 0.104
1.032AlaTrp: 1.032 ± 0.049
2.469AlaTyr: 2.469 ± 0.061
0.0AlaXaa: 0.0 ± 0.0
Cys
0.688CysAla: 0.688 ± 0.034
0.137CysCys: 0.137 ± 0.017
0.609CysAsp: 0.609 ± 0.035
0.526CysGlu: 0.526 ± 0.032
0.436CysPhe: 0.436 ± 0.025
0.803CysGly: 0.803 ± 0.042
0.332CysHis: 0.332 ± 0.026
0.529CysIle: 0.529 ± 0.029
0.394CysLys: 0.394 ± 0.028
0.975CysLeu: 0.975 ± 0.04
0.23CysMet: 0.23 ± 0.019
0.379CysAsn: 0.379 ± 0.025
0.414CysPro: 0.414 ± 0.026
0.801CysGln: 0.801 ± 0.043
0.364CysArg: 0.364 ± 0.028
0.482CysSer: 0.482 ± 0.028
0.417CysThr: 0.417 ± 0.027
0.701CysVal: 0.701 ± 0.035
0.063CysTrp: 0.063 ± 0.011
0.339CysTyr: 0.339 ± 0.028
0.0CysXaa: 0.0 ± 0.0
Asp
3.797AspAla: 3.797 ± 0.088
0.532AspCys: 0.532 ± 0.031
3.701AspAsp: 3.701 ± 0.098
3.851AspGlu: 3.851 ± 0.088
2.978AspPhe: 2.978 ± 0.08
3.522AspGly: 3.522 ± 0.09
0.93AspHis: 0.93 ± 0.051
3.948AspIle: 3.948 ± 0.09
4.784AspLys: 4.784 ± 0.102
5.697AspLeu: 5.697 ± 0.109
1.501AspMet: 1.501 ± 0.053
3.816AspAsn: 3.816 ± 0.09
1.881AspPro: 1.881 ± 0.058
1.432AspGln: 1.432 ± 0.049
2.005AspArg: 2.005 ± 0.06
3.076AspSer: 3.076 ± 0.078
3.227AspThr: 3.227 ± 0.068
3.969AspVal: 3.969 ± 0.082
0.858AspTrp: 0.858 ± 0.041
2.08AspTyr: 2.08 ± 0.062
0.0AspXaa: 0.0 ± 0.0
Glu
3.634GluAla: 3.634 ± 0.095
0.359GluCys: 0.359 ± 0.026
1.864GluAsp: 1.864 ± 0.062
2.108GluGlu: 2.108 ± 0.08
2.12GluPhe: 2.12 ± 0.06
2.162GluGly: 2.162 ± 0.074
1.264GluHis: 1.264 ± 0.048
3.787GluIle: 3.787 ± 0.085
3.636GluLys: 3.636 ± 0.109
5.23GluLeu: 5.23 ± 0.103
1.324GluMet: 1.324 ± 0.051
3.11GluAsn: 3.11 ± 0.089
1.639GluPro: 1.639 ± 0.055
3.772GluGln: 3.772 ± 0.085
2.771GluArg: 2.771 ± 0.079
2.402GluSer: 2.402 ± 0.076
2.754GluThr: 2.754 ± 0.067
2.951GluVal: 2.951 ± 0.084
0.506GluTrp: 0.506 ± 0.029
1.42GluTyr: 1.42 ± 0.051
0.0GluXaa: 0.0 ± 0.0
Phe
4.15PheAla: 4.15 ± 0.101
0.628PheCys: 0.628 ± 0.033
3.372PheAsp: 3.372 ± 0.078
2.152PheGlu: 2.152 ± 0.061
1.988PhePhe: 1.988 ± 0.064
3.722PheGly: 3.722 ± 0.088
0.823PheHis: 0.823 ± 0.036
2.884PheIle: 2.884 ± 0.074
1.844PheLys: 1.844 ± 0.066
3.824PheLeu: 3.824 ± 0.106
1.115PheMet: 1.115 ± 0.045
2.397PheAsn: 2.397 ± 0.07
1.067PhePro: 1.067 ± 0.044
1.08PheGln: 1.08 ± 0.047
1.239PheArg: 1.239 ± 0.041
2.794PheSer: 2.794 ± 0.071
2.147PheThr: 2.147 ± 0.066
3.078PheVal: 3.078 ± 0.086
0.551PheTrp: 0.551 ± 0.034
1.524PheTyr: 1.524 ± 0.053
0.0PheXaa: 0.0 ± 0.0
Gly
4.6GlyAla: 4.6 ± 0.106
0.696GlyCys: 0.696 ± 0.037
3.293GlyAsp: 3.293 ± 0.09
3.797GlyGlu: 3.797 ± 0.081
3.424GlyPhe: 3.424 ± 0.079
4.407GlyGly: 4.407 ± 0.126
1.285GlyHis: 1.285 ± 0.046
4.585GlyIle: 4.585 ± 0.084
4.649GlyLys: 4.649 ± 0.09
6.782GlyLeu: 6.782 ± 0.128
2.065GlyMet: 2.065 ± 0.06
2.781GlyAsn: 2.781 ± 0.075
0.714GlyPro: 0.714 ± 0.04
2.657GlyGln: 2.657 ± 0.077
2.729GlyArg: 2.729 ± 0.083
3.41GlySer: 3.41 ± 0.089
2.823GlyThr: 2.823 ± 0.075
5.311GlyVal: 5.311 ± 0.116
0.729GlyTrp: 0.729 ± 0.039
2.414GlyTyr: 2.414 ± 0.07
0.0GlyXaa: 0.0 ± 0.0
His
2.197HisAla: 2.197 ± 0.072
0.232HisCys: 0.232 ± 0.019
1.477HisAsp: 1.477 ± 0.066
1.282HisGlu: 1.282 ± 0.045
0.96HisPhe: 0.96 ± 0.041
1.501HisGly: 1.501 ± 0.058
0.808HisHis: 0.808 ± 0.055
1.582HisIle: 1.582 ± 0.059
1.335HisLys: 1.335 ± 0.055
2.325HisLeu: 2.325 ± 0.074
0.496HisMet: 0.496 ± 0.033
1.185HisAsn: 1.185 ± 0.05
0.988HisPro: 0.988 ± 0.043
1.277HisGln: 1.277 ± 0.052
0.988HisArg: 0.988 ± 0.04
1.254HisSer: 1.254 ± 0.045
1.362HisThr: 1.362 ± 0.045
1.138HisVal: 1.138 ± 0.046
0.314HisTrp: 0.314 ± 0.024
0.808HisTyr: 0.808 ± 0.037
0.0HisXaa: 0.0 ± 0.0
Ile
6.673IleAla: 6.673 ± 0.123
0.716IleCys: 0.716 ± 0.041
4.862IleAsp: 4.862 ± 0.092
3.836IleGlu: 3.836 ± 0.082
2.631IlePhe: 2.631 ± 0.073
5.144IleGly: 5.144 ± 0.116
1.576IleHis: 1.576 ± 0.049
3.879IleIle: 3.879 ± 0.105
3.984IleLys: 3.984 ± 0.085
5.931IleLeu: 5.931 ± 0.109
1.529IleMet: 1.529 ± 0.057
3.908IleAsn: 3.908 ± 0.096
2.784IlePro: 2.784 ± 0.081
2.537IleGln: 2.537 ± 0.075
2.551IleArg: 2.551 ± 0.067
4.103IleSer: 4.103 ± 0.085
3.858IleThr: 3.858 ± 0.088
4.529IleVal: 4.529 ± 0.102
0.681IleTrp: 0.681 ± 0.034
2.02IleTyr: 2.02 ± 0.059
0.0IleXaa: 0.0 ± 0.0
Lys
5.161LysAla: 5.161 ± 0.103
0.337LysCys: 0.337 ± 0.024
3.358LysAsp: 3.358 ± 0.095
2.711LysGlu: 2.711 ± 0.087
2.217LysPhe: 2.217 ± 0.069
3.176LysGly: 3.176 ± 0.086
1.611LysHis: 1.611 ± 0.056
4.7LysIle: 4.7 ± 0.091
4.021LysLys: 4.021 ± 0.083
6.209LysLeu: 6.209 ± 0.123
1.464LysMet: 1.464 ± 0.049
4.498LysAsn: 4.498 ± 0.104
3.272LysPro: 3.272 ± 0.086
4.477LysGln: 4.477 ± 0.088
2.669LysArg: 2.669 ± 0.064
3.552LysSer: 3.552 ± 0.088
4.942LysThr: 4.942 ± 0.106
3.609LysVal: 3.609 ± 0.083
0.524LysTrp: 0.524 ± 0.032
1.582LysTyr: 1.582 ± 0.061
0.0LysXaa: 0.0 ± 0.0
Leu
10.693LeuAla: 10.693 ± 0.162
0.955LeuCys: 0.955 ± 0.041
6.164LeuAsp: 6.164 ± 0.114
4.437LeuGlu: 4.437 ± 0.102
3.971LeuPhe: 3.971 ± 0.098
6.421LeuGly: 6.421 ± 0.124
2.277LeuHis: 2.277 ± 0.07
6.505LeuIle: 6.505 ± 0.124
5.941LeuLys: 5.941 ± 0.12
10.382LeuLeu: 10.382 ± 0.201
2.507LeuMet: 2.507 ± 0.075
5.684LeuAsn: 5.684 ± 0.114
5.316LeuPro: 5.316 ± 0.093
5.36LeuGln: 5.36 ± 0.142
3.707LeuArg: 3.707 ± 0.093
7.157LeuSer: 7.157 ± 0.12
6.974LeuThr: 6.974 ± 0.12
6.211LeuVal: 6.211 ± 0.129
0.971LeuTrp: 0.971 ± 0.047
2.551LeuTyr: 2.551 ± 0.069
0.0LeuXaa: 0.0 ± 0.0
Met
2.248MetAla: 2.248 ± 0.067
0.177MetCys: 0.177 ± 0.016
1.098MetAsp: 1.098 ± 0.049
0.813MetGlu: 0.813 ± 0.034
0.895MetPhe: 0.895 ± 0.041
1.819MetGly: 1.819 ± 0.06
0.521MetHis: 0.521 ± 0.029
1.734MetIle: 1.734 ± 0.056
1.294MetLys: 1.294 ± 0.042
2.903MetLeu: 2.903 ± 0.081
0.724MetMet: 0.724 ± 0.04
1.289MetAsn: 1.289 ± 0.043
1.536MetPro: 1.536 ± 0.057
1.547MetGln: 1.547 ± 0.057
1.007MetArg: 1.007 ± 0.047
1.651MetSer: 1.651 ± 0.043
1.809MetThr: 1.809 ± 0.054
1.686MetVal: 1.686 ± 0.058
0.189MetTrp: 0.189 ± 0.018
0.559MetTyr: 0.559 ± 0.03
0.0MetXaa: 0.0 ± 0.0
Asn
4.639AsnAla: 4.639 ± 0.101
0.511AsnCys: 0.511 ± 0.028
3.06AsnAsp: 3.06 ± 0.076
2.657AsnGlu: 2.657 ± 0.07
2.392AsnPhe: 2.392 ± 0.068
3.015AsnGly: 3.015 ± 0.088
1.763AsnHis: 1.763 ± 0.065
3.627AsnIle: 3.627 ± 0.094
3.247AsnLys: 3.247 ± 0.095
6.052AsnLeu: 6.052 ± 0.118
1.224AsnMet: 1.224 ± 0.043
3.627AsnAsn: 3.627 ± 0.135
3.096AsnPro: 3.096 ± 0.077
3.868AsnGln: 3.868 ± 0.108
2.235AsnArg: 2.235 ± 0.066
2.943AsnSer: 2.943 ± 0.085
3.352AsnThr: 3.352 ± 0.093
3.133AsnVal: 3.133 ± 0.095
0.743AsnTrp: 0.743 ± 0.038
1.724AsnTyr: 1.724 ± 0.054
0.0AsnXaa: 0.0 ± 0.0
Pro
2.574ProAla: 2.574 ± 0.065
0.349ProCys: 0.349 ± 0.024
2.283ProAsp: 2.283 ± 0.064
1.859ProGlu: 1.859 ± 0.064
1.683ProPhe: 1.683 ± 0.053
0.97ProGly: 0.97 ± 0.055
0.79ProHis: 0.79 ± 0.035
3.151ProIle: 3.151 ± 0.07
3.305ProLys: 3.305 ± 0.078
3.677ProLeu: 3.677 ± 0.072
1.098ProMet: 1.098 ± 0.039
3.031ProAsn: 3.031 ± 0.07
1.37ProPro: 1.37 ± 0.055
1.597ProGln: 1.597 ± 0.052
1.163ProArg: 1.163 ± 0.044
2.322ProSer: 2.322 ± 0.067
2.936ProThr: 2.936 ± 0.077
2.621ProVal: 2.621 ± 0.073
0.284ProTrp: 0.284 ± 0.021
1.287ProTyr: 1.287 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
5.291GlnAla: 5.291 ± 0.104
0.317GlnCys: 0.317 ± 0.027
2.44GlnAsp: 2.44 ± 0.071
1.938GlnGlu: 1.938 ± 0.065
1.94GlnPhe: 1.94 ± 0.06
2.981GlnGly: 2.981 ± 0.075
1.405GlnHis: 1.405 ± 0.068
3.722GlnIle: 3.722 ± 0.09
3.627GlnLys: 3.627 ± 0.079
5.57GlnLeu: 5.57 ± 0.134
1.319GlnMet: 1.319 ± 0.049
3.605GlnAsn: 3.605 ± 0.107
1.948GlnPro: 1.948 ± 0.071
3.948GlnGln: 3.948 ± 0.187
1.946GlnArg: 1.946 ± 0.064
2.913GlnSer: 2.913 ± 0.074
3.308GlnThr: 3.308 ± 0.089
3.275GlnVal: 3.275 ± 0.079
0.439GlnTrp: 0.439 ± 0.027
1.457GlnTyr: 1.457 ± 0.057
0.0GlnXaa: 0.0 ± 0.0
Arg
2.686ArgAla: 2.686 ± 0.066
0.357ArgCys: 0.357 ± 0.026
1.948ArgAsp: 1.948 ± 0.062
2.212ArgGlu: 2.212 ± 0.067
2.038ArgPhe: 2.038 ± 0.053
2.342ArgGly: 2.342 ± 0.076
1.058ArgHis: 1.058 ± 0.046
2.756ArgIle: 2.756 ± 0.068
2.025ArgLys: 2.025 ± 0.059
4.817ArgLeu: 4.817 ± 0.101
1.008ArgMet: 1.008 ± 0.045
1.536ArgAsn: 1.536 ± 0.049
1.517ArgPro: 1.517 ± 0.056
2.377ArgGln: 2.377 ± 0.065
1.853ArgArg: 1.853 ± 0.058
1.961ArgSer: 1.961 ± 0.065
1.981ArgThr: 1.981 ± 0.062
2.405ArgVal: 2.405 ± 0.064
0.426ArgTrp: 0.426 ± 0.025
1.654ArgTyr: 1.654 ± 0.059
0.0ArgXaa: 0.0 ± 0.0
Ser
4.473SerAla: 4.473 ± 0.097
0.501SerCys: 0.501 ± 0.033
3.522SerAsp: 3.522 ± 0.084
3.035SerGlu: 3.035 ± 0.077
2.425SerPhe: 2.425 ± 0.065
3.958SerGly: 3.958 ± 0.087
1.457SerHis: 1.457 ± 0.056
3.662SerIle: 3.662 ± 0.078
3.133SerLys: 3.133 ± 0.071
5.967SerLeu: 5.967 ± 0.1
1.392SerMet: 1.392 ± 0.051
2.788SerAsn: 2.788 ± 0.074
2.073SerPro: 2.073 ± 0.071
3.3SerGln: 3.3 ± 0.089
2.314SerArg: 2.314 ± 0.061
3.03SerSer: 3.03 ± 0.091
3.031SerThr: 3.031 ± 0.084
4.275SerVal: 4.275 ± 0.076
0.558SerTrp: 0.558 ± 0.029
1.781SerTyr: 1.781 ± 0.062
0.0SerXaa: 0.0 ± 0.0
Thr
5.455ThrAla: 5.455 ± 0.106
0.522ThrCys: 0.522 ± 0.032
3.756ThrAsp: 3.756 ± 0.08
2.778ThrGlu: 2.778 ± 0.072
2.122ThrPhe: 2.122 ± 0.055
4.475ThrGly: 4.475 ± 0.098
1.501ThrHis: 1.501 ± 0.051
3.555ThrIle: 3.555 ± 0.074
3.751ThrLys: 3.751 ± 0.087
6.438ThrLeu: 6.438 ± 0.1
1.143ThrMet: 1.143 ± 0.046
3.0ThrAsn: 3.0 ± 0.088
3.008ThrPro: 3.008 ± 0.077
3.135ThrGln: 3.135 ± 0.094
1.794ThrArg: 1.794 ± 0.058
2.978ThrSer: 2.978 ± 0.072
4.024ThrThr: 4.024 ± 0.099
3.881ThrVal: 3.881 ± 0.093
0.566ThrTrp: 0.566 ± 0.03
1.496ThrTyr: 1.496 ± 0.049
0.0ThrXaa: 0.0 ± 0.0
Val
6.451ValAla: 6.451 ± 0.1
0.744ValCys: 0.744 ± 0.036
3.686ValAsp: 3.686 ± 0.088
3.071ValGlu: 3.071 ± 0.091
2.846ValPhe: 2.846 ± 0.076
4.485ValGly: 4.485 ± 0.098
1.254ValHis: 1.254 ± 0.043
5.019ValIle: 5.019 ± 0.091
4.1ValLys: 4.1 ± 0.093
7.236ValLeu: 7.236 ± 0.119
1.938ValMet: 1.938 ± 0.061
3.542ValAsn: 3.542 ± 0.086
1.758ValPro: 1.758 ± 0.06
2.666ValGln: 2.666 ± 0.07
2.602ValArg: 2.602 ± 0.065
3.878ValSer: 3.878 ± 0.08
3.397ValThr: 3.397 ± 0.086
4.969ValVal: 4.969 ± 0.11
0.729ValTrp: 0.729 ± 0.036
1.91ValTyr: 1.91 ± 0.057
0.0ValXaa: 0.0 ± 0.0
Trp
0.709TrpAla: 0.709 ± 0.032
0.103TrpCys: 0.103 ± 0.013
0.351TrpAsp: 0.351 ± 0.024
0.396TrpGlu: 0.396 ± 0.027
0.558TrpPhe: 0.558 ± 0.034
0.599TrpGly: 0.599 ± 0.038
0.356TrpHis: 0.356 ± 0.023
0.594TrpIle: 0.594 ± 0.033
0.294TrpLys: 0.294 ± 0.022
1.821TrpLeu: 1.821 ± 0.072
0.16TrpMet: 0.16 ± 0.015
0.257TrpAsn: 0.257 ± 0.022
0.139TrpPro: 0.139 ± 0.015
1.561TrpGln: 1.561 ± 0.065
0.517TrpArg: 0.517 ± 0.03
0.409TrpSer: 0.409 ± 0.026
0.461TrpThr: 0.461 ± 0.027
0.866TrpVal: 0.866 ± 0.042
0.144TrpTrp: 0.144 ± 0.017
0.372TrpTyr: 0.372 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.536TyrAla: 2.536 ± 0.068
0.337TyrCys: 0.337 ± 0.024
1.866TyrAsp: 1.866 ± 0.06
1.527TyrGlu: 1.527 ± 0.052
1.496TyrPhe: 1.496 ± 0.052
1.998TyrGly: 1.998 ± 0.058
0.938TyrHis: 0.938 ± 0.038
1.549TyrIle: 1.549 ± 0.054
1.511TyrLys: 1.511 ± 0.063
3.262TyrLeu: 3.262 ± 0.077
0.568TyrMet: 0.568 ± 0.031
1.374TyrAsn: 1.374 ± 0.057
1.369TyrPro: 1.369 ± 0.051
2.472TyrGln: 2.472 ± 0.07
1.601TyrArg: 1.601 ± 0.056
1.477TyrSer: 1.477 ± 0.052
1.446TyrThr: 1.446 ± 0.047
1.761TyrVal: 1.761 ± 0.06
0.361TyrTrp: 0.361 ± 0.026
1.058TyrTyr: 1.058 ± 0.05
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1822 proteins (599093 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski