Amino acid dipepetide frequency for Spissistilus festinus reovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.861AlaAla: 4.861 ± 1.153
1.246AlaCys: 1.246 ± 0.359
3.864AlaAsp: 3.864 ± 0.435
3.739AlaGlu: 3.739 ± 0.667
2.617AlaPhe: 2.617 ± 0.421
3.615AlaGly: 3.615 ± 0.741
2.244AlaHis: 2.244 ± 0.407
4.612AlaIle: 4.612 ± 0.444
2.119AlaLys: 2.119 ± 0.547
7.728AlaLeu: 7.728 ± 0.796
2.368AlaMet: 2.368 ± 0.496
3.615AlaAsn: 3.615 ± 0.396
3.739AlaPro: 3.739 ± 0.603
2.867AlaGln: 2.867 ± 0.546
4.487AlaArg: 4.487 ± 0.551
6.107AlaSer: 6.107 ± 0.873
4.487AlaThr: 4.487 ± 0.864
4.986AlaVal: 4.986 ± 0.408
0.872AlaTrp: 0.872 ± 0.303
2.991AlaTyr: 2.991 ± 0.504
0.0AlaXaa: 0.0 ± 0.0
Cys
0.748CysAla: 0.748 ± 0.531
0.249CysCys: 0.249 ± 0.174
0.872CysAsp: 0.872 ± 0.314
0.748CysGlu: 0.748 ± 0.277
0.125CysPhe: 0.125 ± 0.113
0.872CysGly: 0.872 ± 0.317
0.249CysHis: 0.249 ± 0.124
1.122CysIle: 1.122 ± 0.451
0.125CysLys: 0.125 ± 0.137
1.496CysLeu: 1.496 ± 0.281
0.499CysMet: 0.499 ± 0.164
0.499CysAsn: 0.499 ± 0.179
0.374CysPro: 0.374 ± 0.203
0.499CysGln: 0.499 ± 0.154
0.997CysArg: 0.997 ± 0.314
1.496CysSer: 1.496 ± 0.253
0.499CysThr: 0.499 ± 0.206
0.997CysVal: 0.997 ± 0.165
0.125CysTrp: 0.125 ± 0.095
0.499CysTyr: 0.499 ± 0.157
0.0CysXaa: 0.0 ± 0.0
Asp
3.49AspAla: 3.49 ± 0.476
1.246AspCys: 1.246 ± 0.52
4.238AspAsp: 4.238 ± 0.802
2.493AspGlu: 2.493 ± 0.41
1.496AspPhe: 1.496 ± 0.367
2.742AspGly: 2.742 ± 0.599
0.997AspHis: 0.997 ± 0.375
3.365AspIle: 3.365 ± 0.516
2.368AspLys: 2.368 ± 0.557
5.235AspLeu: 5.235 ± 1.329
1.246AspMet: 1.246 ± 0.209
1.994AspAsn: 1.994 ± 0.43
3.365AspPro: 3.365 ± 0.439
1.994AspGln: 1.994 ± 0.315
3.365AspArg: 3.365 ± 0.746
3.615AspSer: 3.615 ± 0.488
2.742AspThr: 2.742 ± 0.51
4.736AspVal: 4.736 ± 0.813
0.748AspTrp: 0.748 ± 0.28
1.62AspTyr: 1.62 ± 0.384
0.0AspXaa: 0.0 ± 0.0
Glu
3.116GluAla: 3.116 ± 0.581
0.374GluCys: 0.374 ± 0.186
2.617GluAsp: 2.617 ± 0.528
2.244GluGlu: 2.244 ± 0.746
2.742GluPhe: 2.742 ± 0.492
2.742GluGly: 2.742 ± 0.338
1.371GluHis: 1.371 ± 0.371
2.991GluIle: 2.991 ± 0.664
1.62GluLys: 1.62 ± 0.433
3.49GluLeu: 3.49 ± 0.712
0.872GluMet: 0.872 ± 0.339
0.748GluAsn: 0.748 ± 0.362
2.368GluPro: 2.368 ± 0.604
1.745GluGln: 1.745 ± 0.376
3.49GluArg: 3.49 ± 0.824
3.365GluSer: 3.365 ± 0.66
2.991GluThr: 2.991 ± 0.293
4.362GluVal: 4.362 ± 0.426
0.997GluTrp: 0.997 ± 0.271
2.991GluTyr: 2.991 ± 0.513
0.0GluXaa: 0.0 ± 0.0
Phe
1.994PheAla: 1.994 ± 0.608
0.872PheCys: 0.872 ± 0.307
2.617PheAsp: 2.617 ± 0.703
1.994PheGlu: 1.994 ± 0.3
1.62PhePhe: 1.62 ± 0.452
2.244PheGly: 2.244 ± 0.462
0.997PheHis: 0.997 ± 0.366
1.87PheIle: 1.87 ± 0.297
2.244PheLys: 2.244 ± 0.377
2.617PheLeu: 2.617 ± 0.437
1.246PheMet: 1.246 ± 0.345
1.62PheAsn: 1.62 ± 0.422
2.991PhePro: 2.991 ± 0.474
2.867PheGln: 2.867 ± 0.467
1.87PheArg: 1.87 ± 0.324
2.742PheSer: 2.742 ± 0.484
2.244PheThr: 2.244 ± 0.452
2.493PheVal: 2.493 ± 0.625
0.125PheTrp: 0.125 ± 0.113
0.748PheTyr: 0.748 ± 0.289
0.0PheXaa: 0.0 ± 0.0
Gly
3.864GlyAla: 3.864 ± 0.534
0.623GlyCys: 0.623 ± 0.255
2.742GlyAsp: 2.742 ± 0.541
3.365GlyGlu: 3.365 ± 0.44
2.368GlyPhe: 2.368 ± 0.287
3.615GlyGly: 3.615 ± 0.616
0.872GlyHis: 0.872 ± 0.306
2.368GlyIle: 2.368 ± 0.39
2.742GlyLys: 2.742 ± 0.674
6.731GlyLeu: 6.731 ± 0.931
1.994GlyMet: 1.994 ± 0.464
1.745GlyAsn: 1.745 ± 0.48
1.994GlyPro: 1.994 ± 0.387
2.244GlyGln: 2.244 ± 0.42
3.241GlyArg: 3.241 ± 0.393
5.235GlySer: 5.235 ± 0.703
4.113GlyThr: 4.113 ± 0.455
4.861GlyVal: 4.861 ± 0.638
0.872GlyTrp: 0.872 ± 0.317
2.119GlyTyr: 2.119 ± 0.411
0.0GlyXaa: 0.0 ± 0.0
His
2.119HisAla: 2.119 ± 0.694
0.249HisCys: 0.249 ± 0.137
0.997HisAsp: 0.997 ± 0.287
0.249HisGlu: 0.249 ± 0.125
1.122HisPhe: 1.122 ± 0.299
1.745HisGly: 1.745 ± 0.392
0.623HisHis: 0.623 ± 0.207
1.246HisIle: 1.246 ± 0.335
0.249HisLys: 0.249 ± 0.126
3.49HisLeu: 3.49 ± 0.928
0.623HisMet: 0.623 ± 0.231
0.623HisAsn: 0.623 ± 0.5
1.87HisPro: 1.87 ± 0.548
0.748HisGln: 0.748 ± 0.243
1.745HisArg: 1.745 ± 0.357
2.368HisSer: 2.368 ± 0.51
1.246HisThr: 1.246 ± 0.385
1.87HisVal: 1.87 ± 0.509
0.623HisTrp: 0.623 ± 0.16
1.122HisTyr: 1.122 ± 0.375
0.0HisXaa: 0.0 ± 0.0
Ile
4.612IleAla: 4.612 ± 0.727
0.748IleCys: 0.748 ± 0.133
2.742IleAsp: 2.742 ± 0.312
2.493IleGlu: 2.493 ± 0.28
1.87IlePhe: 1.87 ± 0.406
2.742IleGly: 2.742 ± 0.63
1.371IleHis: 1.371 ± 0.371
3.989IleIle: 3.989 ± 0.382
2.617IleLys: 2.617 ± 0.547
3.739IleLeu: 3.739 ± 0.511
0.748IleMet: 0.748 ± 0.315
2.119IleAsn: 2.119 ± 0.632
4.113IlePro: 4.113 ± 0.55
2.368IleGln: 2.368 ± 0.674
3.49IleArg: 3.49 ± 0.451
5.484IleSer: 5.484 ± 0.443
5.36IleThr: 5.36 ± 0.822
4.238IleVal: 4.238 ± 0.864
0.997IleTrp: 0.997 ± 0.232
2.368IleTyr: 2.368 ± 0.439
0.0IleXaa: 0.0 ± 0.0
Lys
2.368LysAla: 2.368 ± 0.559
0.249LysCys: 0.249 ± 0.167
2.244LysAsp: 2.244 ± 0.35
2.244LysGlu: 2.244 ± 0.617
1.122LysPhe: 1.122 ± 0.275
2.867LysGly: 2.867 ± 0.688
0.748LysHis: 0.748 ± 0.281
2.617LysIle: 2.617 ± 0.616
1.62LysLys: 1.62 ± 0.589
4.487LysLeu: 4.487 ± 0.487
0.374LysMet: 0.374 ± 0.156
1.496LysAsn: 1.496 ± 0.527
1.496LysPro: 1.496 ± 0.29
1.246LysGln: 1.246 ± 0.32
2.742LysArg: 2.742 ± 0.385
3.241LysSer: 3.241 ± 0.654
1.87LysThr: 1.87 ± 0.77
3.615LysVal: 3.615 ± 0.681
0.872LysTrp: 0.872 ± 0.276
1.122LysTyr: 1.122 ± 0.5
0.0LysXaa: 0.0 ± 0.0
Leu
7.603LeuAla: 7.603 ± 0.524
1.745LeuCys: 1.745 ± 0.333
5.484LeuAsp: 5.484 ± 0.726
3.365LeuGlu: 3.365 ± 0.529
3.116LeuPhe: 3.116 ± 0.802
6.606LeuGly: 6.606 ± 1.222
2.742LeuHis: 2.742 ± 0.233
5.11LeuIle: 5.11 ± 0.768
3.989LeuLys: 3.989 ± 0.757
9.847LeuLeu: 9.847 ± 0.937
1.246LeuMet: 1.246 ± 0.512
3.989LeuAsn: 3.989 ± 0.45
7.852LeuPro: 7.852 ± 1.192
3.615LeuGln: 3.615 ± 0.532
5.734LeuArg: 5.734 ± 1.128
10.47LeuSer: 10.47 ± 1.076
7.229LeuThr: 7.229 ± 0.841
5.983LeuVal: 5.983 ± 0.595
1.246LeuTrp: 1.246 ± 0.482
3.615LeuTyr: 3.615 ± 0.541
0.0LeuXaa: 0.0 ± 0.0
Met
1.87MetAla: 1.87 ± 0.377
0.125MetCys: 0.125 ± 0.111
1.122MetAsp: 1.122 ± 0.191
1.122MetGlu: 1.122 ± 0.421
0.997MetPhe: 0.997 ± 0.293
0.748MetGly: 0.748 ± 0.197
0.623MetHis: 0.623 ± 0.127
1.122MetIle: 1.122 ± 0.338
0.499MetLys: 0.499 ± 0.348
2.493MetLeu: 2.493 ± 0.54
0.748MetMet: 0.748 ± 0.185
0.997MetAsn: 0.997 ± 0.544
0.374MetPro: 0.374 ± 0.32
0.872MetGln: 0.872 ± 0.366
0.872MetArg: 0.872 ± 0.263
3.116MetSer: 3.116 ± 0.615
0.997MetThr: 0.997 ± 0.189
2.244MetVal: 2.244 ± 0.486
0.374MetTrp: 0.374 ± 0.233
0.374MetTyr: 0.374 ± 0.32
0.0MetXaa: 0.0 ± 0.0
Asn
3.365AsnAla: 3.365 ± 0.804
0.249AsnCys: 0.249 ± 0.154
1.62AsnAsp: 1.62 ± 0.47
2.244AsnGlu: 2.244 ± 0.55
1.745AsnPhe: 1.745 ± 0.412
2.493AsnGly: 2.493 ± 0.587
1.371AsnHis: 1.371 ± 0.474
2.368AsnIle: 2.368 ± 0.658
0.623AsnLys: 0.623 ± 0.252
4.986AsnLeu: 4.986 ± 0.408
1.122AsnMet: 1.122 ± 0.235
0.872AsnAsn: 0.872 ± 0.186
1.994AsnPro: 1.994 ± 0.578
1.246AsnGln: 1.246 ± 0.281
1.994AsnArg: 1.994 ± 0.483
2.368AsnSer: 2.368 ± 0.498
1.62AsnThr: 1.62 ± 0.447
4.612AsnVal: 4.612 ± 0.816
0.872AsnTrp: 0.872 ± 0.267
1.496AsnTyr: 1.496 ± 0.357
0.0AsnXaa: 0.0 ± 0.0
Pro
3.864ProAla: 3.864 ± 0.614
1.122ProCys: 1.122 ± 0.364
2.119ProAsp: 2.119 ± 0.418
2.368ProGlu: 2.368 ± 0.422
1.87ProPhe: 1.87 ± 0.362
3.116ProGly: 3.116 ± 0.264
1.745ProHis: 1.745 ± 0.516
3.365ProIle: 3.365 ± 0.916
2.244ProLys: 2.244 ± 0.405
5.11ProLeu: 5.11 ± 0.835
0.623ProMet: 0.623 ± 0.198
3.864ProAsn: 3.864 ± 0.757
4.238ProPro: 4.238 ± 0.504
2.119ProGln: 2.119 ± 0.661
2.244ProArg: 2.244 ± 0.496
5.36ProSer: 5.36 ± 0.694
4.487ProThr: 4.487 ± 0.569
4.362ProVal: 4.362 ± 0.545
0.623ProTrp: 0.623 ± 0.298
2.493ProTyr: 2.493 ± 0.574
0.0ProXaa: 0.0 ± 0.0
Gln
2.742GlnAla: 2.742 ± 0.59
0.249GlnCys: 0.249 ± 0.148
1.745GlnAsp: 1.745 ± 0.336
1.371GlnGlu: 1.371 ± 0.508
0.997GlnPhe: 0.997 ± 0.361
1.87GlnGly: 1.87 ± 0.433
1.122GlnHis: 1.122 ± 0.567
2.368GlnIle: 2.368 ± 0.428
1.496GlnLys: 1.496 ± 0.489
3.989GlnLeu: 3.989 ± 0.935
0.748GlnMet: 0.748 ± 0.209
1.62GlnAsn: 1.62 ± 0.3
1.994GlnPro: 1.994 ± 0.383
1.62GlnGln: 1.62 ± 0.4
2.867GlnArg: 2.867 ± 0.294
3.116GlnSer: 3.116 ± 0.452
1.745GlnThr: 1.745 ± 0.401
3.365GlnVal: 3.365 ± 0.687
0.623GlnTrp: 0.623 ± 0.243
1.745GlnTyr: 1.745 ± 0.298
0.0GlnXaa: 0.0 ± 0.0
Arg
6.107ArgAla: 6.107 ± 0.795
0.748ArgCys: 0.748 ± 0.262
3.615ArgAsp: 3.615 ± 0.577
2.493ArgGlu: 2.493 ± 0.56
2.867ArgPhe: 2.867 ± 0.775
2.617ArgGly: 2.617 ± 0.618
1.371ArgHis: 1.371 ± 0.367
2.867ArgIle: 2.867 ± 0.459
2.742ArgLys: 2.742 ± 0.477
4.986ArgLeu: 4.986 ± 0.431
0.748ArgMet: 0.748 ± 0.298
1.496ArgAsn: 1.496 ± 0.227
2.991ArgPro: 2.991 ± 0.43
1.745ArgGln: 1.745 ± 0.374
2.617ArgArg: 2.617 ± 0.475
3.615ArgSer: 3.615 ± 0.603
3.49ArgThr: 3.49 ± 0.591
5.484ArgVal: 5.484 ± 0.644
0.374ArgTrp: 0.374 ± 0.191
2.617ArgTyr: 2.617 ± 0.715
0.0ArgXaa: 0.0 ± 0.0
Ser
6.98SerAla: 6.98 ± 0.445
0.997SerCys: 0.997 ± 0.474
5.36SerAsp: 5.36 ± 0.917
3.365SerGlu: 3.365 ± 0.295
2.493SerPhe: 2.493 ± 0.42
5.484SerGly: 5.484 ± 0.717
1.87SerHis: 1.87 ± 0.259
5.609SerIle: 5.609 ± 0.773
3.116SerLys: 3.116 ± 0.53
9.348SerLeu: 9.348 ± 0.603
2.368SerMet: 2.368 ± 0.318
2.867SerAsn: 2.867 ± 0.472
5.11SerPro: 5.11 ± 1.147
2.368SerGln: 2.368 ± 0.412
3.49SerArg: 3.49 ± 0.564
9.971SerSer: 9.971 ± 1.146
6.232SerThr: 6.232 ± 0.898
6.606SerVal: 6.606 ± 1.019
1.246SerTrp: 1.246 ± 0.415
4.362SerTyr: 4.362 ± 0.958
0.0SerXaa: 0.0 ± 0.0
Thr
3.864ThrAla: 3.864 ± 0.565
0.872ThrCys: 0.872 ± 0.221
2.244ThrAsp: 2.244 ± 0.668
3.365ThrGlu: 3.365 ± 0.575
3.365ThrPhe: 3.365 ± 0.42
3.989ThrGly: 3.989 ± 0.862
1.87ThrHis: 1.87 ± 0.273
4.113ThrIle: 4.113 ± 0.889
2.368ThrLys: 2.368 ± 0.684
6.481ThrLeu: 6.481 ± 0.44
1.62ThrMet: 1.62 ± 0.26
2.742ThrAsn: 2.742 ± 0.458
3.241ThrPro: 3.241 ± 0.402
2.617ThrGln: 2.617 ± 0.482
3.241ThrArg: 3.241 ± 0.439
5.734ThrSer: 5.734 ± 0.939
4.362ThrThr: 4.362 ± 0.615
4.487ThrVal: 4.487 ± 0.766
1.122ThrTrp: 1.122 ± 0.472
2.119ThrTyr: 2.119 ± 0.333
0.0ThrXaa: 0.0 ± 0.0
Val
4.736ValAla: 4.736 ± 1.054
0.374ValCys: 0.374 ± 0.167
3.615ValAsp: 3.615 ± 0.568
4.238ValGlu: 4.238 ± 0.578
2.742ValPhe: 2.742 ± 0.666
5.36ValGly: 5.36 ± 0.771
1.371ValHis: 1.371 ± 0.43
5.11ValIle: 5.11 ± 0.55
3.615ValLys: 3.615 ± 0.79
8.476ValLeu: 8.476 ± 1.019
1.87ValMet: 1.87 ± 0.454
3.116ValAsn: 3.116 ± 0.434
5.609ValPro: 5.609 ± 0.481
2.368ValGln: 2.368 ± 0.51
3.365ValArg: 3.365 ± 0.648
8.102ValSer: 8.102 ± 1.288
5.36ValThr: 5.36 ± 0.608
5.484ValVal: 5.484 ± 0.785
0.374ValTrp: 0.374 ± 0.169
2.867ValTyr: 2.867 ± 0.572
0.0ValXaa: 0.0 ± 0.0
Trp
1.246TrpAla: 1.246 ± 0.28
0.125TrpCys: 0.125 ± 0.113
0.748TrpAsp: 0.748 ± 0.288
1.122TrpGlu: 1.122 ± 0.217
0.623TrpPhe: 0.623 ± 0.307
0.374TrpGly: 0.374 ± 0.148
0.125TrpHis: 0.125 ± 0.095
0.748TrpIle: 0.748 ± 0.322
1.122TrpLys: 1.122 ± 0.297
1.371TrpLeu: 1.371 ± 0.128
0.374TrpMet: 0.374 ± 0.154
0.623TrpAsn: 0.623 ± 0.282
0.623TrpPro: 0.623 ± 0.32
0.249TrpGln: 0.249 ± 0.164
1.246TrpArg: 1.246 ± 0.366
0.997TrpSer: 0.997 ± 0.508
0.499TrpThr: 0.499 ± 0.201
0.499TrpVal: 0.499 ± 0.186
0.125TrpTrp: 0.125 ± 0.118
0.623TrpTyr: 0.623 ± 0.217
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.739TyrAla: 3.739 ± 0.496
0.623TyrCys: 0.623 ± 0.152
2.493TyrAsp: 2.493 ± 0.572
2.617TyrGlu: 2.617 ± 0.714
2.119TyrPhe: 2.119 ± 0.413
1.87TyrGly: 1.87 ± 0.615
1.246TyrHis: 1.246 ± 0.26
1.246TyrIle: 1.246 ± 0.389
1.122TyrLys: 1.122 ± 0.273
4.487TyrLeu: 4.487 ± 0.906
0.125TyrMet: 0.125 ± 0.137
2.617TyrAsn: 2.617 ± 0.429
0.997TyrPro: 0.997 ± 0.392
1.994TyrGln: 1.994 ± 0.512
2.493TyrArg: 2.493 ± 0.43
2.742TyrSer: 2.742 ± 0.541
2.244TyrThr: 2.244 ± 0.61
2.867TyrVal: 2.867 ± 0.264
0.249TyrTrp: 0.249 ± 0.16
1.496TyrTyr: 1.496 ± 0.348
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (8024 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski