Amino acid dipepetide frequency for Sistotremastrum suecicum HHB10207 ss-3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.243AlaAla: 7.243 ± 0.05
1.0AlaCys: 1.0 ± 0.014
3.846AlaAsp: 3.846 ± 0.03
4.563AlaGlu: 4.563 ± 0.037
3.276AlaPhe: 3.276 ± 0.025
4.737AlaGly: 4.737 ± 0.031
1.9AlaHis: 1.9 ± 0.019
4.204AlaIle: 4.204 ± 0.027
3.647AlaLys: 3.647 ± 0.035
8.298AlaLeu: 8.298 ± 0.045
1.696AlaMet: 1.696 ± 0.019
2.703AlaAsn: 2.703 ± 0.025
4.727AlaPro: 4.727 ± 0.041
3.147AlaGln: 3.147 ± 0.026
4.699AlaArg: 4.699 ± 0.031
7.452AlaSer: 7.452 ± 0.043
4.835AlaThr: 4.835 ± 0.029
4.909AlaVal: 4.909 ± 0.03
1.108AlaTrp: 1.108 ± 0.015
2.033AlaTyr: 2.033 ± 0.021
0.0AlaXaa: 0.0 ± 0.0
Cys
0.906CysAla: 0.906 ± 0.014
0.234CysCys: 0.234 ± 0.007
0.664CysAsp: 0.664 ± 0.012
0.61CysGlu: 0.61 ± 0.01
0.529CysPhe: 0.529 ± 0.01
0.869CysGly: 0.869 ± 0.014
0.366CysHis: 0.366 ± 0.009
0.714CysIle: 0.714 ± 0.012
0.472CysLys: 0.472 ± 0.01
1.386CysLeu: 1.386 ± 0.019
0.248CysMet: 0.248 ± 0.006
0.406CysAsn: 0.406 ± 0.01
0.806CysPro: 0.806 ± 0.015
0.483CysGln: 0.483 ± 0.01
0.826CysArg: 0.826 ± 0.011
1.038CysSer: 1.038 ± 0.018
0.753CysThr: 0.753 ± 0.012
0.81CysVal: 0.81 ± 0.013
0.219CysTrp: 0.219 ± 0.006
0.322CysTyr: 0.322 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
4.468AspAla: 4.468 ± 0.028
0.638AspCys: 0.638 ± 0.01
4.032AspAsp: 4.032 ± 0.034
4.291AspGlu: 4.291 ± 0.032
2.143AspPhe: 2.143 ± 0.023
3.67AspGly: 3.67 ± 0.027
1.378AspHis: 1.378 ± 0.018
3.18AspIle: 3.18 ± 0.025
2.03AspLys: 2.03 ± 0.021
5.336AspLeu: 5.336 ± 0.036
1.094AspMet: 1.094 ± 0.014
1.676AspAsn: 1.676 ± 0.019
3.596AspPro: 3.596 ± 0.028
1.782AspGln: 1.782 ± 0.021
2.991AspArg: 2.991 ± 0.027
4.224AspSer: 4.224 ± 0.035
2.804AspThr: 2.804 ± 0.025
3.811AspVal: 3.811 ± 0.029
0.9AspTrp: 0.9 ± 0.014
1.404AspTyr: 1.404 ± 0.016
0.0AspXaa: 0.0 ± 0.0
Glu
4.743GluAla: 4.743 ± 0.036
0.687GluCys: 0.687 ± 0.011
3.994GluAsp: 3.994 ± 0.037
5.005GluGlu: 5.005 ± 0.038
1.979GluPhe: 1.979 ± 0.017
3.533GluGly: 3.533 ± 0.028
1.42GluHis: 1.42 ± 0.017
3.237GluIle: 3.237 ± 0.023
3.159GluLys: 3.159 ± 0.033
5.303GluLeu: 5.303 ± 0.036
1.303GluMet: 1.303 ± 0.017
2.104GluAsn: 2.104 ± 0.019
2.796GluPro: 2.796 ± 0.028
2.081GluGln: 2.081 ± 0.021
3.975GluArg: 3.975 ± 0.033
4.421GluSer: 4.421 ± 0.028
3.28GluThr: 3.28 ± 0.023
3.461GluVal: 3.461 ± 0.027
0.939GluTrp: 0.939 ± 0.012
1.495GluTyr: 1.495 ± 0.018
0.0GluXaa: 0.0 ± 0.0
Phe
3.014PheAla: 3.014 ± 0.024
0.567PheCys: 0.567 ± 0.01
2.386PheAsp: 2.386 ± 0.02
2.221PheGlu: 2.221 ± 0.02
1.688PhePhe: 1.688 ± 0.018
2.725PheGly: 2.725 ± 0.026
1.019PheHis: 1.019 ± 0.014
2.049PheIle: 2.049 ± 0.022
1.513PheLys: 1.513 ± 0.017
3.906PheLeu: 3.906 ± 0.03
0.728PheMet: 0.728 ± 0.012
1.372PheAsn: 1.372 ± 0.017
2.272PhePro: 2.272 ± 0.022
1.403PheGln: 1.403 ± 0.015
2.109PheArg: 2.109 ± 0.018
3.42PheSer: 3.42 ± 0.028
2.22PheThr: 2.22 ± 0.021
2.586PheVal: 2.586 ± 0.023
0.64PheTrp: 0.64 ± 0.01
1.06PheTyr: 1.06 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
4.477GlyAla: 4.477 ± 0.033
0.792GlyCys: 0.792 ± 0.014
3.246GlyAsp: 3.246 ± 0.026
3.25GlyGlu: 3.25 ± 0.027
2.548GlyPhe: 2.548 ± 0.023
4.931GlyGly: 4.931 ± 0.047
1.617GlyHis: 1.617 ± 0.019
3.33GlyIle: 3.33 ± 0.024
3.059GlyLys: 3.059 ± 0.026
5.527GlyLeu: 5.527 ± 0.035
1.341GlyMet: 1.341 ± 0.016
2.132GlyAsn: 2.132 ± 0.026
3.353GlyPro: 3.353 ± 0.029
2.134GlyGln: 2.134 ± 0.021
3.755GlyArg: 3.755 ± 0.033
5.497GlySer: 5.497 ± 0.041
3.785GlyThr: 3.785 ± 0.029
3.987GlyVal: 3.987 ± 0.029
1.081GlyTrp: 1.081 ± 0.014
1.784GlyTyr: 1.784 ± 0.022
0.0GlyXaa: 0.0 ± 0.0
His
1.944HisAla: 1.944 ± 0.019
0.377HisCys: 0.377 ± 0.009
1.406HisAsp: 1.406 ± 0.016
1.379HisGlu: 1.379 ± 0.017
1.067HisPhe: 1.067 ± 0.014
1.625HisGly: 1.625 ± 0.02
0.926HisHis: 0.926 ± 0.019
1.418HisIle: 1.418 ± 0.016
0.888HisLys: 0.888 ± 0.013
2.718HisLeu: 2.718 ± 0.024
0.447HisMet: 0.447 ± 0.009
0.866HisAsn: 0.866 ± 0.013
2.021HisPro: 2.021 ± 0.023
0.942HisGln: 0.942 ± 0.016
1.622HisArg: 1.622 ± 0.019
2.358HisSer: 2.358 ± 0.024
1.408HisThr: 1.408 ± 0.016
1.606HisVal: 1.606 ± 0.016
0.369HisTrp: 0.369 ± 0.008
0.705HisTyr: 0.705 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
4.341IleAla: 4.341 ± 0.026
0.79IleCys: 0.79 ± 0.011
2.956IleAsp: 2.956 ± 0.022
2.8IleGlu: 2.8 ± 0.022
2.194IlePhe: 2.194 ± 0.021
3.118IleGly: 3.118 ± 0.029
1.417IleHis: 1.417 ± 0.016
2.759IleIle: 2.759 ± 0.025
2.189IleLys: 2.189 ± 0.018
5.293IleLeu: 5.293 ± 0.044
0.994IleMet: 0.994 ± 0.014
1.761IleAsn: 1.761 ± 0.017
3.616IlePro: 3.616 ± 0.027
1.995IleGln: 1.995 ± 0.019
3.144IleArg: 3.144 ± 0.024
4.536IleSer: 4.536 ± 0.03
2.967IleThr: 2.967 ± 0.024
3.423IleVal: 3.423 ± 0.026
0.8IleTrp: 0.8 ± 0.014
1.422IleTyr: 1.422 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
3.946LysAla: 3.946 ± 0.038
0.49LysCys: 0.49 ± 0.01
2.472LysAsp: 2.472 ± 0.022
3.106LysGlu: 3.106 ± 0.03
1.513LysPhe: 1.513 ± 0.019
2.704LysGly: 2.704 ± 0.024
1.067LysHis: 1.067 ± 0.013
2.363LysIle: 2.363 ± 0.023
2.912LysLys: 2.912 ± 0.038
3.965LysLeu: 3.965 ± 0.029
0.862LysMet: 0.862 ± 0.013
1.528LysAsn: 1.528 ± 0.019
2.514LysPro: 2.514 ± 0.025
1.519LysGln: 1.519 ± 0.016
3.179LysArg: 3.179 ± 0.025
3.534LysSer: 3.534 ± 0.03
2.677LysThr: 2.677 ± 0.024
2.578LysVal: 2.578 ± 0.022
0.689LysTrp: 0.689 ± 0.011
1.217LysTyr: 1.217 ± 0.015
0.0LysXaa: 0.0 ± 0.0
Leu
7.799LeuAla: 7.799 ± 0.038
1.364LeuCys: 1.364 ± 0.018
5.365LeuAsp: 5.365 ± 0.038
5.673LeuGlu: 5.673 ± 0.039
3.635LeuPhe: 3.635 ± 0.03
5.681LeuGly: 5.681 ± 0.039
2.597LeuHis: 2.597 ± 0.021
4.704LeuIle: 4.704 ± 0.034
4.377LeuLys: 4.377 ± 0.037
9.219LeuLeu: 9.219 ± 0.05
1.746LeuMet: 1.746 ± 0.02
3.333LeuAsn: 3.333 ± 0.023
6.529LeuPro: 6.529 ± 0.04
3.794LeuGln: 3.794 ± 0.026
6.328LeuArg: 6.328 ± 0.041
8.938LeuSer: 8.938 ± 0.052
5.388LeuThr: 5.388 ± 0.03
5.728LeuVal: 5.728 ± 0.042
1.316LeuTrp: 1.316 ± 0.018
2.454LeuTyr: 2.454 ± 0.019
0.0LeuXaa: 0.0 ± 0.0
Met
1.726MetAla: 1.726 ± 0.02
0.23MetCys: 0.23 ± 0.006
1.156MetAsp: 1.156 ± 0.016
1.131MetGlu: 1.131 ± 0.014
0.714MetPhe: 0.714 ± 0.012
1.206MetGly: 1.206 ± 0.016
0.495MetHis: 0.495 ± 0.01
1.003MetIle: 1.003 ± 0.015
0.976MetLys: 0.976 ± 0.014
1.695MetLeu: 1.695 ± 0.017
0.483MetMet: 0.483 ± 0.011
0.755MetAsn: 0.755 ± 0.012
1.214MetPro: 1.214 ± 0.018
0.72MetGln: 0.72 ± 0.012
1.214MetArg: 1.214 ± 0.017
2.001MetSer: 2.001 ± 0.019
1.241MetThr: 1.241 ± 0.016
1.03MetVal: 1.03 ± 0.015
0.255MetTrp: 0.255 ± 0.006
0.442MetTyr: 0.442 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
3.005AsnAla: 3.005 ± 0.024
0.419AsnCys: 0.419 ± 0.009
1.771AsnAsp: 1.771 ± 0.018
1.872AsnGlu: 1.872 ± 0.017
1.355AsnPhe: 1.355 ± 0.014
2.514AsnGly: 2.514 ± 0.027
0.888AsnHis: 0.888 ± 0.013
2.046AsnIle: 2.046 ± 0.02
1.294AsnLys: 1.294 ± 0.017
3.414AsnLeu: 3.414 ± 0.028
0.705AsnMet: 0.705 ± 0.011
1.248AsnAsn: 1.248 ± 0.018
2.569AsnPro: 2.569 ± 0.024
1.208AsnGln: 1.208 ± 0.015
1.867AsnArg: 1.867 ± 0.02
2.791AsnSer: 2.791 ± 0.028
2.032AsnThr: 2.032 ± 0.024
2.36AsnVal: 2.36 ± 0.02
0.516AsnTrp: 0.516 ± 0.01
0.887AsnTyr: 0.887 ± 0.013
0.0AsnXaa: 0.0 ± 0.0
Pro
4.97ProAla: 4.97 ± 0.041
0.563ProCys: 0.563 ± 0.01
3.388ProAsp: 3.388 ± 0.027
3.77ProGlu: 3.77 ± 0.032
2.446ProPhe: 2.446 ± 0.023
3.589ProGly: 3.589 ± 0.035
1.674ProHis: 1.674 ± 0.017
3.046ProIle: 3.046 ± 0.023
2.578ProLys: 2.578 ± 0.027
5.644ProLeu: 5.644 ± 0.033
1.027ProMet: 1.027 ± 0.016
2.39ProAsn: 2.39 ± 0.024
6.521ProPro: 6.521 ± 0.082
2.364ProGln: 2.364 ± 0.028
3.646ProArg: 3.646 ± 0.035
7.729ProSer: 7.729 ± 0.057
4.369ProThr: 4.369 ± 0.035
3.689ProVal: 3.689 ± 0.032
0.738ProTrp: 0.738 ± 0.011
1.577ProTyr: 1.577 ± 0.017
0.0ProXaa: 0.0 ± 0.0
Gln
3.086GlnAla: 3.086 ± 0.027
0.485GlnCys: 0.485 ± 0.01
1.915GlnAsp: 1.915 ± 0.02
2.088GlnGlu: 2.088 ± 0.021
1.33GlnPhe: 1.33 ± 0.017
2.043GlnGly: 2.043 ± 0.022
0.981GlnHis: 0.981 ± 0.016
1.981GlnIle: 1.981 ± 0.018
1.699GlnLys: 1.699 ± 0.022
3.364GlnLeu: 3.364 ± 0.025
0.761GlnMet: 0.761 ± 0.011
1.452GlnAsn: 1.452 ± 0.018
2.243GlnPro: 2.243 ± 0.028
1.638GlnGln: 1.638 ± 0.031
2.376GlnArg: 2.376 ± 0.025
3.365GlnSer: 3.365 ± 0.029
2.354GlnThr: 2.354 ± 0.021
2.014GlnVal: 2.014 ± 0.02
0.576GlnTrp: 0.576 ± 0.01
1.087GlnTyr: 1.087 ± 0.014
0.0GlnXaa: 0.0 ± 0.0
Arg
4.693ArgAla: 4.693 ± 0.031
0.795ArgCys: 0.795 ± 0.012
3.281ArgAsp: 3.281 ± 0.027
3.703ArgGlu: 3.703 ± 0.031
2.256ArgPhe: 2.256 ± 0.02
3.447ArgGly: 3.447 ± 0.028
1.718ArgHis: 1.718 ± 0.016
3.204ArgIle: 3.204 ± 0.024
3.242ArgLys: 3.242 ± 0.027
5.92ArgLeu: 5.92 ± 0.038
1.289ArgMet: 1.289 ± 0.016
2.139ArgAsn: 2.139 ± 0.018
3.576ArgPro: 3.576 ± 0.033
2.266ArgGln: 2.266 ± 0.021
4.996ArgArg: 4.996 ± 0.047
5.362ArgSer: 5.362 ± 0.037
3.548ArgThr: 3.548 ± 0.028
3.533ArgVal: 3.533 ± 0.028
0.975ArgTrp: 0.975 ± 0.013
1.671ArgTyr: 1.671 ± 0.02
0.0ArgXaa: 0.0 ± 0.0
Ser
6.899SerAla: 6.899 ± 0.041
1.016SerCys: 1.016 ± 0.013
4.65SerAsp: 4.65 ± 0.033
4.464SerGlu: 4.464 ± 0.033
3.584SerPhe: 3.584 ± 0.029
5.402SerGly: 5.402 ± 0.038
2.445SerHis: 2.445 ± 0.024
4.566SerIle: 4.566 ± 0.034
3.725SerLys: 3.725 ± 0.025
8.933SerLeu: 8.933 ± 0.051
1.692SerMet: 1.692 ± 0.017
3.19SerAsn: 3.19 ± 0.029
6.652SerPro: 6.652 ± 0.061
3.491SerGln: 3.491 ± 0.031
5.509SerArg: 5.509 ± 0.036
11.357SerSer: 11.357 ± 0.099
6.424SerThr: 6.424 ± 0.05
5.113SerVal: 5.113 ± 0.033
1.158SerTrp: 1.158 ± 0.015
2.156SerTyr: 2.156 ± 0.021
0.0SerXaa: 0.0 ± 0.0
Thr
4.699ThrAla: 4.699 ± 0.031
0.77ThrCys: 0.77 ± 0.01
2.768ThrAsp: 2.768 ± 0.02
2.929ThrGlu: 2.929 ± 0.025
2.507ThrPhe: 2.507 ± 0.02
3.627ThrGly: 3.627 ± 0.028
1.477ThrHis: 1.477 ± 0.019
3.222ThrIle: 3.222 ± 0.028
2.46ThrLys: 2.46 ± 0.02
6.085ThrLeu: 6.085 ± 0.033
1.098ThrMet: 1.098 ± 0.014
1.999ThrAsn: 1.999 ± 0.024
4.67ThrPro: 4.67 ± 0.042
2.055ThrGln: 2.055 ± 0.02
3.347ThrArg: 3.347 ± 0.028
6.265ThrSer: 6.265 ± 0.047
4.161ThrThr: 4.161 ± 0.04
3.647ThrVal: 3.647 ± 0.028
0.857ThrTrp: 0.857 ± 0.012
1.523ThrTyr: 1.523 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
5.081ValAla: 5.081 ± 0.034
0.807ValCys: 0.807 ± 0.013
3.682ValAsp: 3.682 ± 0.025
3.767ValGlu: 3.767 ± 0.028
2.476ValPhe: 2.476 ± 0.023
3.643ValGly: 3.643 ± 0.03
1.569ValHis: 1.569 ± 0.017
3.187ValIle: 3.187 ± 0.026
2.793ValLys: 2.793 ± 0.024
6.02ValLeu: 6.02 ± 0.039
1.235ValMet: 1.235 ± 0.014
2.085ValAsn: 2.085 ± 0.021
3.826ValPro: 3.826 ± 0.034
2.29ValGln: 2.29 ± 0.025
3.449ValArg: 3.449 ± 0.025
4.825ValSer: 4.825 ± 0.031
3.421ValThr: 3.421 ± 0.03
4.271ValVal: 4.271 ± 0.033
0.907ValTrp: 0.907 ± 0.013
1.632ValTyr: 1.632 ± 0.02
0.0ValXaa: 0.0 ± 0.0
Trp
1.044TrpAla: 1.044 ± 0.013
0.218TrpCys: 0.218 ± 0.007
0.931TrpAsp: 0.931 ± 0.017
0.858TrpGlu: 0.858 ± 0.013
0.555TrpPhe: 0.555 ± 0.011
0.835TrpGly: 0.835 ± 0.012
0.373TrpHis: 0.373 ± 0.009
0.886TrpIle: 0.886 ± 0.013
0.824TrpLys: 0.824 ± 0.013
1.304TrpLeu: 1.304 ± 0.014
0.382TrpMet: 0.382 ± 0.009
0.67TrpAsn: 0.67 ± 0.011
0.639TrpPro: 0.639 ± 0.011
0.517TrpGln: 0.517 ± 0.011
1.024TrpArg: 1.024 ± 0.013
1.21TrpSer: 1.21 ± 0.013
0.966TrpThr: 0.966 ± 0.014
0.83TrpVal: 0.83 ± 0.012
0.273TrpTrp: 0.273 ± 0.007
0.397TrpTyr: 0.397 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.939TyrAla: 1.939 ± 0.02
0.423TyrCys: 0.423 ± 0.009
1.539TyrAsp: 1.539 ± 0.021
1.435TyrGlu: 1.435 ± 0.014
1.103TyrPhe: 1.103 ± 0.014
1.729TyrGly: 1.729 ± 0.02
0.764TyrHis: 0.764 ± 0.013
1.415TyrIle: 1.415 ± 0.017
1.0TyrLys: 1.0 ± 0.015
2.636TyrLeu: 2.636 ± 0.024
0.554TyrMet: 0.554 ± 0.009
0.953TyrAsn: 0.953 ± 0.011
1.576TyrPro: 1.576 ± 0.018
1.009TyrGln: 1.009 ± 0.016
1.558TyrArg: 1.558 ± 0.017
2.106TyrSer: 2.106 ± 0.024
1.532TyrThr: 1.532 ± 0.017
1.579TyrVal: 1.579 ± 0.016
0.42TyrTrp: 0.42 ± 0.008
0.835TyrTyr: 0.835 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13633 proteins (5578206 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski