Amino acid dipepetide frequency for Phytohabitans houttuyneae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	24.088AlaAla: 24.088 ± 0.15	1.093AlaCys: 1.093 ± 0.019	8.132AlaAsp: 8.132 ± 0.057	7.807AlaGlu: 7.807 ± 0.059	3.588AlaPhe: 3.588 ± 0.039	14.687AlaGly: 14.687 ± 0.074	2.663AlaHis: 2.663 ± 0.032	4.391AlaIle: 4.391 ± 0.042	2.324AlaLys: 2.324 ± 0.034	14.421AlaLeu: 14.421 ± 0.096	2.591AlaMet: 2.591 ± 0.034	2.317AlaAsn: 2.317 ± 0.033	7.124AlaPro: 7.124 ± 0.057	3.646AlaGln: 3.646 ± 0.039	10.611AlaArg: 10.611 ± 0.065	6.349AlaSer: 6.349 ± 0.053	8.333AlaThr: 8.333 ± 0.056	12.943AlaVal: 12.943 ± 0.083	2.1AlaTrp: 2.1 ± 0.025	2.866AlaTyr: 2.866 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	1.037CysAla: 1.037 ± 0.02	0.131CysCys: 0.131 ± 0.006	0.47CysAsp: 0.47 ± 0.013	0.337CysGlu: 0.337 ± 0.011	0.214CysPhe: 0.214 ± 0.008	0.974CysGly: 0.974 ± 0.017	0.201CysHis: 0.201 ± 0.008	0.141CysIle: 0.141 ± 0.007	0.094CysLys: 0.094 ± 0.005	0.703CysLeu: 0.703 ± 0.016	0.129CysMet: 0.129 ± 0.006	0.142CysAsn: 0.142 ± 0.007	0.506CysPro: 0.506 ± 0.014	0.207CysGln: 0.207 ± 0.007	0.681CysArg: 0.681 ± 0.015	0.446CysSer: 0.446 ± 0.012	0.472CysThr: 0.472 ± 0.013	0.617CysVal: 0.617 ± 0.014	0.155CysTrp: 0.155 ± 0.008	0.166CysTyr: 0.166 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	7.554AspAla: 7.554 ± 0.063	0.38AspCys: 0.38 ± 0.011	3.545AspAsp: 3.545 ± 0.036	3.689AspGlu: 3.689 ± 0.039	1.544AspPhe: 1.544 ± 0.024	6.629AspGly: 6.629 ± 0.063	1.315AspHis: 1.315 ± 0.021	1.735AspIle: 1.735 ± 0.027	0.975AspLys: 0.975 ± 0.023	6.706AspLeu: 6.706 ± 0.05	0.747AspMet: 0.747 ± 0.016	1.012AspAsn: 1.012 ± 0.018	4.614AspPro: 4.614 ± 0.044	1.634AspGln: 1.634 ± 0.022	5.097AspArg: 5.097 ± 0.045	2.323AspSer: 2.323 ± 0.029	2.872AspThr: 2.872 ± 0.036	4.952AspVal: 4.952 ± 0.038	0.98AspTrp: 0.98 ± 0.016	1.155AspTyr: 1.155 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	6.812GluAla: 6.812 ± 0.061	0.334GluCys: 0.334 ± 0.011	2.192GluAsp: 2.192 ± 0.027	2.539GluGlu: 2.539 ± 0.032	1.385GluPhe: 1.385 ± 0.019	3.471GluGly: 3.471 ± 0.035	1.308GluHis: 1.308 ± 0.022	1.965GluIle: 1.965 ± 0.027	0.925GluLys: 0.925 ± 0.019	5.912GluLeu: 5.912 ± 0.052	0.823GluMet: 0.823 ± 0.017	0.738GluAsn: 0.738 ± 0.015	3.394GluPro: 3.394 ± 0.037	1.956GluGln: 1.956 ± 0.027	5.215GluArg: 5.215 ± 0.056	2.242GluSer: 2.242 ± 0.025	2.39GluThr: 2.39 ± 0.027	4.605GluVal: 4.605 ± 0.04	0.79GluTrp: 0.79 ± 0.015	1.062GluTyr: 1.062 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.957PheAla: 3.957 ± 0.035	0.241PheCys: 0.241 ± 0.007	2.081PheAsp: 2.081 ± 0.026	1.353PheGlu: 1.353 ± 0.023	0.899PhePhe: 0.899 ± 0.019	2.982PheGly: 2.982 ± 0.034	0.562PheHis: 0.562 ± 0.015	0.758PheIle: 0.758 ± 0.017	0.403PheLys: 0.403 ± 0.013	2.433PheLeu: 2.433 ± 0.032	0.382PheMet: 0.382 ± 0.011	0.624PheAsn: 0.624 ± 0.015	1.321PhePro: 1.321 ± 0.021	0.733PheGln: 0.733 ± 0.015	1.826PheArg: 1.826 ± 0.026	1.343PheSer: 1.343 ± 0.021	1.977PheThr: 1.977 ± 0.03	2.458PheVal: 2.458 ± 0.032	0.442PheTrp: 0.442 ± 0.012	0.628PheTyr: 0.628 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	11.245GlyAla: 11.245 ± 0.076	0.859GlyCys: 0.859 ± 0.016	5.441GlyAsp: 5.441 ± 0.052	4.754GlyGlu: 4.754 ± 0.04	2.87GlyPhe: 2.87 ± 0.032	9.21GlyGly: 9.21 ± 0.078	2.151GlyHis: 2.151 ± 0.032	3.249GlyIle: 3.249 ± 0.034	1.89GlyLys: 1.89 ± 0.029	9.126GlyLeu: 9.126 ± 0.056	1.84GlyMet: 1.84 ± 0.028	1.801GlyAsn: 1.801 ± 0.031	5.208GlyPro: 5.208 ± 0.05	2.88GlyGln: 2.88 ± 0.031	7.801GlyArg: 7.801 ± 0.056	4.917GlySer: 4.917 ± 0.045	5.988GlyThr: 5.988 ± 0.059	7.962GlyVal: 7.962 ± 0.062	2.013GlyTrp: 2.013 ± 0.027	2.465GlyTyr: 2.465 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	2.631HisAla: 2.631 ± 0.026	0.185HisCys: 0.185 ± 0.007	1.293HisAsp: 1.293 ± 0.018	1.071HisGlu: 1.071 ± 0.017	0.572HisPhe: 0.572 ± 0.012	2.069HisGly: 2.069 ± 0.025	0.647HisHis: 0.647 ± 0.015	0.624HisIle: 0.624 ± 0.013	0.271HisLys: 0.271 ± 0.009	2.468HisLeu: 2.468 ± 0.029	0.295HisMet: 0.295 ± 0.009	0.415HisAsn: 0.415 ± 0.011	1.707HisPro: 1.707 ± 0.027	0.61HisGln: 0.61 ± 0.015	2.074HisArg: 2.074 ± 0.024	0.911HisSer: 0.911 ± 0.016	1.179HisThr: 1.179 ± 0.021	1.708HisVal: 1.708 ± 0.028	0.347HisTrp: 0.347 ± 0.012	0.438HisTyr: 0.438 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.942IleAla: 4.942 ± 0.044	0.281IleCys: 0.281 ± 0.008	2.345IleAsp: 2.345 ± 0.028	1.941IleGlu: 1.941 ± 0.027	0.846IlePhe: 0.846 ± 0.016	3.475IleGly: 3.475 ± 0.039	0.607IleHis: 0.607 ± 0.013	0.924IleIle: 0.924 ± 0.019	0.619IleLys: 0.619 ± 0.015	2.53IleLeu: 2.53 ± 0.03	0.449IleMet: 0.449 ± 0.012	0.752IleAsn: 0.752 ± 0.017	1.7IlePro: 1.7 ± 0.025	0.778IleGln: 0.778 ± 0.016	2.437IleArg: 2.437 ± 0.03	1.701IleSer: 1.701 ± 0.026	2.072IleThr: 2.072 ± 0.026	2.969IleVal: 2.969 ± 0.031	0.457IleTrp: 0.457 ± 0.012	0.648IleTyr: 0.648 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	2.277LysAla: 2.277 ± 0.034	0.101LysCys: 0.101 ± 0.006	0.814LysAsp: 0.814 ± 0.017	0.762LysGlu: 0.762 ± 0.017	0.367LysPhe: 0.367 ± 0.012	1.259LysGly: 1.259 ± 0.023	0.365LysHis: 0.365 ± 0.011	0.697LysIle: 0.697 ± 0.016	0.425LysLys: 0.425 ± 0.016	1.678LysLeu: 1.678 ± 0.025	0.299LysMet: 0.299 ± 0.01	0.311LysAsn: 0.311 ± 0.011	1.104LysPro: 1.104 ± 0.021	0.543LysGln: 0.543 ± 0.014	1.277LysArg: 1.277 ± 0.025	0.859LysSer: 0.859 ± 0.016	0.987LysThr: 0.987 ± 0.02	1.619LysVal: 1.619 ± 0.027	0.247LysTrp: 0.247 ± 0.008	0.35LysTyr: 0.35 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	16.408LeuAla: 16.408 ± 0.094	0.778LeuCys: 0.778 ± 0.014	6.917LeuAsp: 6.917 ± 0.059	3.91LeuGlu: 3.91 ± 0.036	2.617LeuPhe: 2.617 ± 0.034	8.918LeuGly: 8.918 ± 0.062	2.112LeuHis: 2.112 ± 0.026	3.176LeuIle: 3.176 ± 0.039	1.412LeuLys: 1.412 ± 0.026	10.808LeuLeu: 10.808 ± 0.088	1.484LeuMet: 1.484 ± 0.023	1.659LeuAsn: 1.659 ± 0.025	6.462LeuPro: 6.462 ± 0.049	2.015LeuGln: 2.015 ± 0.027	8.938LeuArg: 8.938 ± 0.06	5.314LeuSer: 5.314 ± 0.046	6.469LeuThr: 6.469 ± 0.046	9.477LeuVal: 9.477 ± 0.069	1.353LeuTrp: 1.353 ± 0.022	1.803LeuTyr: 1.803 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.218MetAla: 2.218 ± 0.026	0.123MetCys: 0.123 ± 0.006	0.799MetAsp: 0.799 ± 0.016	0.636MetGlu: 0.636 ± 0.014	0.489MetPhe: 0.489 ± 0.013	1.19MetGly: 1.19 ± 0.019	0.338MetHis: 0.338 ± 0.01	0.638MetIle: 0.638 ± 0.015	0.318MetLys: 0.318 ± 0.01	1.82MetLeu: 1.82 ± 0.029	0.262MetMet: 0.262 ± 0.009	0.338MetAsn: 0.338 ± 0.011	1.122MetPro: 1.122 ± 0.022	0.418MetGln: 0.418 ± 0.012	1.575MetArg: 1.575 ± 0.022	1.207MetSer: 1.207 ± 0.019	1.415MetThr: 1.415 ± 0.022	1.395MetVal: 1.395 ± 0.023	0.25MetTrp: 0.25 ± 0.009	0.309MetTyr: 0.309 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.279AsnAla: 2.279 ± 0.03	0.166AsnCys: 0.166 ± 0.007	0.967AsnAsp: 0.967 ± 0.021	0.784AsnGlu: 0.784 ± 0.016	0.527AsnPhe: 0.527 ± 0.013	2.029AsnGly: 2.029 ± 0.034	0.394AsnHis: 0.394 ± 0.011	0.638AsnIle: 0.638 ± 0.017	0.321AsnLys: 0.321 ± 0.01	1.823AsnLeu: 1.823 ± 0.026	0.262AsnMet: 0.262 ± 0.009	0.511AsnAsn: 0.511 ± 0.018	1.49AsnPro: 1.49 ± 0.025	0.606AsnGln: 0.606 ± 0.015	1.299AsnArg: 1.299 ± 0.022	0.9AsnSer: 0.9 ± 0.02	1.175AsnThr: 1.175 ± 0.028	1.454AsnVal: 1.454 ± 0.026	0.311AsnTrp: 0.311 ± 0.01	0.459AsnTyr: 0.459 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	9.698ProAla: 9.698 ± 0.072	0.36ProCys: 0.36 ± 0.01	4.777ProAsp: 4.777 ± 0.055	3.604ProGlu: 3.604 ± 0.039	1.552ProPhe: 1.552 ± 0.022	6.249ProGly: 6.249 ± 0.059	1.245ProHis: 1.245 ± 0.02	1.728ProIle: 1.728 ± 0.023	0.927ProLys: 0.927 ± 0.015	5.276ProLeu: 5.276 ± 0.041	1.084ProMet: 1.084 ± 0.018	1.072ProAsn: 1.072 ± 0.021	4.663ProPro: 4.663 ± 0.078	1.543ProGln: 1.543 ± 0.026	4.107ProArg: 4.107 ± 0.04	3.408ProSer: 3.408 ± 0.042	3.773ProThr: 3.773 ± 0.048	5.448ProVal: 5.448 ± 0.041	0.978ProTrp: 0.978 ± 0.018	1.287ProTyr: 1.287 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.81GlnAla: 3.81 ± 0.04	0.158GlnCys: 0.158 ± 0.007	1.147GlnAsp: 1.147 ± 0.018	1.188GlnGlu: 1.188 ± 0.018	0.741GlnPhe: 0.741 ± 0.015	1.878GlnGly: 1.878 ± 0.025	0.63GlnHis: 0.63 ± 0.016	1.123GlnIle: 1.123 ± 0.02	0.428GlnLys: 0.428 ± 0.013	3.07GlnLeu: 3.07 ± 0.032	0.473GlnMet: 0.473 ± 0.012	0.462GlnAsn: 0.462 ± 0.012	1.915GlnPro: 1.915 ± 0.03	1.161GlnGln: 1.161 ± 0.025	2.687GlnArg: 2.687 ± 0.03	1.218GlnSer: 1.218 ± 0.021	1.398GlnThr: 1.398 ± 0.022	2.704GlnVal: 2.704 ± 0.029	0.547GlnTrp: 0.547 ± 0.015	0.56GlnTyr: 0.56 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	10.373ArgAla: 10.373 ± 0.068	0.709ArgCys: 0.709 ± 0.017	4.629ArgAsp: 4.629 ± 0.044	4.354ArgGlu: 4.354 ± 0.042	2.455ArgPhe: 2.455 ± 0.029	5.994ArgGly: 5.994 ± 0.05	2.163ArgHis: 2.163 ± 0.028	3.046ArgIle: 3.046 ± 0.03	1.287ArgLys: 1.287 ± 0.02	9.34ArgLeu: 9.34 ± 0.069	1.815ArgMet: 1.815 ± 0.022	1.366ArgAsn: 1.366 ± 0.023	5.327ArgPro: 5.327 ± 0.044	2.59ArgGln: 2.59 ± 0.034	8.713ArgArg: 8.713 ± 0.07	4.107ArgSer: 4.107 ± 0.037	4.85ArgThr: 4.85 ± 0.041	6.512ArgVal: 6.512 ± 0.05	1.709ArgTrp: 1.709 ± 0.026	2.121ArgTyr: 2.121 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	6.535SerAla: 6.535 ± 0.049	0.44SerCys: 0.44 ± 0.013	2.486SerAsp: 2.486 ± 0.03	2.006SerGlu: 2.006 ± 0.027	1.474SerPhe: 1.474 ± 0.02	5.912SerGly: 5.912 ± 0.054	0.941SerHis: 0.941 ± 0.016	1.603SerIle: 1.603 ± 0.024	0.775SerLys: 0.775 ± 0.019	4.471SerLeu: 4.471 ± 0.048	1.072SerMet: 1.072 ± 0.019	0.964SerAsn: 0.964 ± 0.02	3.335SerPro: 3.335 ± 0.04	1.24SerGln: 1.24 ± 0.02	3.95SerArg: 3.95 ± 0.034	2.86SerSer: 2.86 ± 0.041	3.407SerThr: 3.407 ± 0.039	4.137SerVal: 4.137 ± 0.037	1.038SerTrp: 1.038 ± 0.021	1.182SerTyr: 1.182 ± 0.017	0.0SerXaa: 0.0 ± 0.0
Thr	8.732ThrAla: 8.732 ± 0.062	0.475ThrCys: 0.475 ± 0.012	3.319ThrAsp: 3.319 ± 0.035	2.659ThrGlu: 2.659 ± 0.03	1.803ThrPhe: 1.803 ± 0.024	6.478ThrGly: 6.478 ± 0.062	1.135ThrHis: 1.135 ± 0.018	2.07ThrIle: 2.07 ± 0.029	0.929ThrLys: 0.929 ± 0.02	5.788ThrLeu: 5.788 ± 0.043	1.022ThrMet: 1.022 ± 0.018	1.22ThrAsn: 1.22 ± 0.024	4.185ThrPro: 4.185 ± 0.051	1.372ThrGln: 1.372 ± 0.023	4.118ThrArg: 4.118 ± 0.038	3.242ThrSer: 3.242 ± 0.038	4.022ThrThr: 4.022 ± 0.05	6.333ThrVal: 6.333 ± 0.051	1.094ThrTrp: 1.094 ± 0.018	1.385ThrTyr: 1.385 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	12.887ValAla: 12.887 ± 0.084	0.668ValCys: 0.668 ± 0.016	5.846ValAsp: 5.846 ± 0.045	4.869ValGlu: 4.869 ± 0.045	2.335ValPhe: 2.335 ± 0.033	7.076ValGly: 7.076 ± 0.053	1.839ValHis: 1.839 ± 0.023	2.888ValIle: 2.888 ± 0.03	1.42ValLys: 1.42 ± 0.022	9.36ValLeu: 9.36 ± 0.072	1.274ValMet: 1.274 ± 0.023	1.757ValAsn: 1.757 ± 0.027	5.324ValPro: 5.324 ± 0.047	2.022ValGln: 2.022 ± 0.025	7.273ValArg: 7.273 ± 0.056	4.391ValSer: 4.391 ± 0.04	6.081ValThr: 6.081 ± 0.055	8.654ValVal: 8.654 ± 0.071	1.209ValTrp: 1.209 ± 0.021	1.687ValTyr: 1.687 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.779TrpAla: 1.779 ± 0.024	0.18TrpCys: 0.18 ± 0.007	0.864TrpAsp: 0.864 ± 0.019	0.678TrpGlu: 0.678 ± 0.013	0.494TrpPhe: 0.494 ± 0.012	1.062TrpGly: 1.062 ± 0.02	0.434TrpHis: 0.434 ± 0.011	0.564TrpIle: 0.564 ± 0.014	0.269TrpLys: 0.269 ± 0.009	2.027TrpLeu: 2.027 ± 0.028	0.301TrpMet: 0.301 ± 0.008	0.448TrpAsn: 0.448 ± 0.015	1.026TrpPro: 1.026 ± 0.019	0.666TrpGln: 0.666 ± 0.015	1.76TrpArg: 1.76 ± 0.025	1.127TrpSer: 1.127 ± 0.02	1.156TrpThr: 1.156 ± 0.022	1.162TrpVal: 1.162 ± 0.018	0.421TrpTrp: 0.421 ± 0.011	0.415TrpTyr: 0.415 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.809TyrAla: 2.809 ± 0.032	0.161TyrCys: 0.161 ± 0.007	1.394TyrAsp: 1.394 ± 0.023	1.118TyrGlu: 1.118 ± 0.022	0.629TyrPhe: 0.629 ± 0.015	2.132TyrGly: 2.132 ± 0.025	0.462TyrHis: 0.462 ± 0.012	0.512TyrIle: 0.512 ± 0.013	0.331TyrLys: 0.331 ± 0.011	2.271TyrLeu: 2.271 ± 0.028	0.255TyrMet: 0.255 ± 0.009	0.487TyrAsn: 0.487 ± 0.014	1.251TyrPro: 1.251 ± 0.019	0.678TyrGln: 0.678 ± 0.015	2.021TyrArg: 2.021 ± 0.024	0.963TyrSer: 0.963 ± 0.017	1.365TyrThr: 1.365 ± 0.023	1.752TyrVal: 1.752 ± 0.027	0.393TyrTrp: 0.393 ± 0.011	0.473TyrTyr: 0.473 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10523 proteins (3370841 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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