Amino acid dipepetide frequency for Sphingobacterium deserti

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.349AlaAla: 6.349 ± 0.1
0.649AlaCys: 0.649 ± 0.024
4.546AlaAsp: 4.546 ± 0.057
4.679AlaGlu: 4.679 ± 0.062
3.587AlaPhe: 3.587 ± 0.052
5.327AlaGly: 5.327 ± 0.078
1.404AlaHis: 1.404 ± 0.036
5.598AlaIle: 5.598 ± 0.067
4.702AlaLys: 4.702 ± 0.066
7.474AlaLeu: 7.474 ± 0.086
1.796AlaMet: 1.796 ± 0.038
3.847AlaAsn: 3.847 ± 0.068
2.263AlaPro: 2.263 ± 0.039
3.142AlaGln: 3.142 ± 0.055
2.957AlaArg: 2.957 ± 0.049
4.91AlaSer: 4.91 ± 0.069
4.125AlaThr: 4.125 ± 0.066
5.137AlaVal: 5.137 ± 0.071
0.897AlaTrp: 0.897 ± 0.027
3.092AlaTyr: 3.092 ± 0.053
0.0AlaXaa: 0.0 ± 0.0
Cys
0.541CysAla: 0.541 ± 0.024
0.117CysCys: 0.117 ± 0.01
0.345CysAsp: 0.345 ± 0.016
0.389CysGlu: 0.389 ± 0.02
0.37CysPhe: 0.37 ± 0.016
0.588CysGly: 0.588 ± 0.025
0.179CysHis: 0.179 ± 0.012
0.56CysIle: 0.56 ± 0.023
0.397CysLys: 0.397 ± 0.02
0.742CysLeu: 0.742 ± 0.024
0.169CysMet: 0.169 ± 0.011
0.329CysAsn: 0.329 ± 0.016
0.268CysPro: 0.268 ± 0.017
0.222CysGln: 0.222 ± 0.012
0.308CysArg: 0.308 ± 0.016
0.531CysSer: 0.531 ± 0.019
0.408CysThr: 0.408 ± 0.021
0.473CysVal: 0.473 ± 0.021
0.082CysTrp: 0.082 ± 0.008
0.315CysTyr: 0.315 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
4.333AspAla: 4.333 ± 0.06
0.351AspCys: 0.351 ± 0.017
2.742AspAsp: 2.742 ± 0.052
3.538AspGlu: 3.538 ± 0.06
3.197AspPhe: 3.197 ± 0.052
4.088AspGly: 4.088 ± 0.067
1.032AspHis: 1.032 ± 0.028
4.152AspIle: 4.152 ± 0.057
3.61AspLys: 3.61 ± 0.054
5.361AspLeu: 5.361 ± 0.063
1.321AspMet: 1.321 ± 0.031
2.784AspAsn: 2.784 ± 0.05
2.095AspPro: 2.095 ± 0.044
1.941AspGln: 1.941 ± 0.041
2.713AspArg: 2.713 ± 0.043
3.16AspSer: 3.16 ± 0.059
2.466AspThr: 2.466 ± 0.048
3.857AspVal: 3.857 ± 0.053
0.839AspTrp: 0.839 ± 0.026
2.612AspTyr: 2.612 ± 0.042
0.0AspXaa: 0.0 ± 0.0
Glu
4.544GluAla: 4.544 ± 0.068
0.296GluCys: 0.296 ± 0.016
3.171GluAsp: 3.171 ± 0.057
4.445GluGlu: 4.445 ± 0.073
2.386GluPhe: 2.386 ± 0.041
3.7GluGly: 3.7 ± 0.046
1.245GluHis: 1.245 ± 0.029
4.433GluIle: 4.433 ± 0.066
4.61GluLys: 4.61 ± 0.071
5.83GluLeu: 5.83 ± 0.079
1.448GluMet: 1.448 ± 0.035
3.499GluAsn: 3.499 ± 0.049
1.554GluPro: 1.554 ± 0.039
2.77GluGln: 2.77 ± 0.054
3.131GluArg: 3.131 ± 0.047
3.361GluSer: 3.361 ± 0.048
3.085GluThr: 3.085 ± 0.053
4.011GluVal: 4.011 ± 0.056
0.647GluTrp: 0.647 ± 0.024
1.999GluTyr: 1.999 ± 0.038
0.0GluXaa: 0.0 ± 0.0
Phe
3.656PheAla: 3.656 ± 0.053
0.446PheCys: 0.446 ± 0.018
3.148PheAsp: 3.148 ± 0.048
2.924PheGlu: 2.924 ± 0.049
2.544PhePhe: 2.544 ± 0.055
3.49PheGly: 3.49 ± 0.045
0.911PheHis: 0.911 ± 0.029
3.143PheIle: 3.143 ± 0.056
2.756PheLys: 2.756 ± 0.043
4.601PheLeu: 4.601 ± 0.064
1.165PheMet: 1.165 ± 0.032
2.667PheAsn: 2.667 ± 0.05
1.768PhePro: 1.768 ± 0.036
1.635PheGln: 1.635 ± 0.037
2.071PheArg: 2.071 ± 0.042
3.727PheSer: 3.727 ± 0.054
2.948PheThr: 2.948 ± 0.05
3.151PheVal: 3.151 ± 0.055
0.596PheTrp: 0.596 ± 0.022
2.058PheTyr: 2.058 ± 0.039
0.0PheXaa: 0.0 ± 0.0
Gly
4.837GlyAla: 4.837 ± 0.075
0.573GlyCys: 0.573 ± 0.023
3.469GlyAsp: 3.469 ± 0.058
3.718GlyGlu: 3.718 ± 0.056
3.535GlyPhe: 3.535 ± 0.051
4.675GlyGly: 4.675 ± 0.078
1.222GlyHis: 1.222 ± 0.031
5.043GlyIle: 5.043 ± 0.067
4.88GlyLys: 4.88 ± 0.065
6.285GlyLeu: 6.285 ± 0.078
1.767GlyMet: 1.767 ± 0.036
3.564GlyAsn: 3.564 ± 0.06
1.468GlyPro: 1.468 ± 0.034
2.43GlyGln: 2.43 ± 0.05
3.058GlyArg: 3.058 ± 0.045
4.424GlySer: 4.424 ± 0.077
3.961GlyThr: 3.961 ± 0.067
4.573GlyVal: 4.573 ± 0.068
0.941GlyTrp: 0.941 ± 0.03
3.103GlyTyr: 3.103 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
1.49HisAla: 1.49 ± 0.037
0.199HisCys: 0.199 ± 0.013
1.009HisAsp: 1.009 ± 0.03
1.065HisGlu: 1.065 ± 0.03
1.118HisPhe: 1.118 ± 0.029
1.255HisGly: 1.255 ± 0.033
0.494HisHis: 0.494 ± 0.02
1.516HisIle: 1.516 ± 0.033
0.968HisLys: 0.968 ± 0.024
1.889HisLeu: 1.889 ± 0.043
0.393HisMet: 0.393 ± 0.016
0.931HisAsn: 0.931 ± 0.023
0.96HisPro: 0.96 ± 0.031
0.772HisGln: 0.772 ± 0.023
0.886HisArg: 0.886 ± 0.023
1.069HisSer: 1.069 ± 0.027
1.039HisThr: 1.039 ± 0.027
1.214HisVal: 1.214 ± 0.033
0.273HisTrp: 0.273 ± 0.016
0.967HisTyr: 0.967 ± 0.026
0.0HisXaa: 0.0 ± 0.0
Ile
5.933IleAla: 5.933 ± 0.073
0.663IleCys: 0.663 ± 0.025
4.472IleAsp: 4.472 ± 0.059
4.204IleGlu: 4.204 ± 0.067
3.148IlePhe: 3.148 ± 0.052
4.912IleGly: 4.912 ± 0.07
1.353IleHis: 1.353 ± 0.034
4.464IleIle: 4.464 ± 0.073
4.088IleLys: 4.088 ± 0.062
6.146IleLeu: 6.146 ± 0.069
1.33IleMet: 1.33 ± 0.035
3.589IleAsn: 3.589 ± 0.06
2.987IlePro: 2.987 ± 0.049
2.597IleGln: 2.597 ± 0.043
3.223IleArg: 3.223 ± 0.045
4.673IleSer: 4.673 ± 0.062
3.761IleThr: 3.761 ± 0.056
4.568IleVal: 4.568 ± 0.062
0.731IleTrp: 0.731 ± 0.026
2.478IleTyr: 2.478 ± 0.045
0.0IleXaa: 0.0 ± 0.0
Lys
4.645LysAla: 4.645 ± 0.069
0.246LysCys: 0.246 ± 0.013
3.777LysAsp: 3.777 ± 0.064
4.479LysGlu: 4.479 ± 0.067
2.438LysPhe: 2.438 ± 0.044
4.022LysGly: 4.022 ± 0.054
1.337LysHis: 1.337 ± 0.033
4.503LysIle: 4.503 ± 0.062
4.642LysLys: 4.642 ± 0.075
5.739LysLeu: 5.739 ± 0.069
1.71LysMet: 1.71 ± 0.038
3.55LysAsn: 3.55 ± 0.053
2.246LysPro: 2.246 ± 0.043
2.65LysGln: 2.65 ± 0.048
2.998LysArg: 2.998 ± 0.051
3.803LysSer: 3.803 ± 0.055
3.523LysThr: 3.523 ± 0.051
3.957LysVal: 3.957 ± 0.054
0.715LysTrp: 0.715 ± 0.026
2.363LysTyr: 2.363 ± 0.04
0.0LysXaa: 0.0 ± 0.0
Leu
7.462LeuAla: 7.462 ± 0.077
0.839LeuCys: 0.839 ± 0.032
5.276LeuAsp: 5.276 ± 0.064
5.327LeuGlu: 5.327 ± 0.07
4.882LeuPhe: 4.882 ± 0.067
6.137LeuGly: 6.137 ± 0.081
1.947LeuHis: 1.947 ± 0.041
6.283LeuIle: 6.283 ± 0.079
6.129LeuLys: 6.129 ± 0.073
9.907LeuLeu: 9.907 ± 0.134
2.198LeuMet: 2.198 ± 0.045
4.977LeuAsn: 4.977 ± 0.073
4.076LeuPro: 4.076 ± 0.055
3.994LeuGln: 3.994 ± 0.065
4.447LeuArg: 4.447 ± 0.05
7.166LeuSer: 7.166 ± 0.079
5.3LeuThr: 5.3 ± 0.065
5.664LeuVal: 5.664 ± 0.077
1.003LeuTrp: 1.003 ± 0.029
3.512LeuTyr: 3.512 ± 0.058
0.0LeuXaa: 0.0 ± 0.0
Met
1.753MetAla: 1.753 ± 0.042
0.142MetCys: 0.142 ± 0.01
1.295MetAsp: 1.295 ± 0.028
1.487MetGlu: 1.487 ± 0.032
0.879MetPhe: 0.879 ± 0.028
1.567MetGly: 1.567 ± 0.039
0.481MetHis: 0.481 ± 0.017
1.385MetIle: 1.385 ± 0.037
1.69MetLys: 1.69 ± 0.037
2.389MetLeu: 2.389 ± 0.047
0.602MetMet: 0.602 ± 0.021
1.21MetAsn: 1.21 ± 0.029
0.988MetPro: 0.988 ± 0.025
1.093MetGln: 1.093 ± 0.032
1.187MetArg: 1.187 ± 0.029
1.452MetSer: 1.452 ± 0.036
1.137MetThr: 1.137 ± 0.033
1.418MetVal: 1.418 ± 0.032
0.225MetTrp: 0.225 ± 0.014
0.729MetTyr: 0.729 ± 0.024
0.0MetXaa: 0.0 ± 0.0
Asn
3.813AsnAla: 3.813 ± 0.065
0.298AsnCys: 0.298 ± 0.017
2.651AsnAsp: 2.651 ± 0.048
2.959AsnGlu: 2.959 ± 0.049
2.643AsnPhe: 2.643 ± 0.055
3.706AsnGly: 3.706 ± 0.064
0.902AsnHis: 0.902 ± 0.029
3.786AsnIle: 3.786 ± 0.06
3.237AsnLys: 3.237 ± 0.051
4.981AsnLeu: 4.981 ± 0.076
1.247AsnMet: 1.247 ± 0.031
2.99AsnAsn: 2.99 ± 0.06
2.615AsnPro: 2.615 ± 0.044
1.922AsnGln: 1.922 ± 0.04
2.506AsnArg: 2.506 ± 0.044
3.206AsnSer: 3.206 ± 0.057
2.92AsnThr: 2.92 ± 0.056
3.376AsnVal: 3.376 ± 0.053
0.737AsnTrp: 0.737 ± 0.025
2.408AsnTyr: 2.408 ± 0.056
0.0AsnXaa: 0.0 ± 0.0
Pro
2.83ProAla: 2.83 ± 0.05
0.211ProCys: 0.211 ± 0.014
2.329ProAsp: 2.329 ± 0.041
2.614ProGlu: 2.614 ± 0.046
1.93ProPhe: 1.93 ± 0.038
2.211ProGly: 2.211 ± 0.048
0.724ProHis: 0.724 ± 0.025
2.507ProIle: 2.507 ± 0.041
2.039ProLys: 2.039 ± 0.048
3.341ProLeu: 3.341 ± 0.055
0.733ProMet: 0.733 ± 0.023
1.962ProAsn: 1.962 ± 0.043
0.867ProPro: 0.867 ± 0.028
1.422ProGln: 1.422 ± 0.03
1.305ProArg: 1.305 ± 0.031
2.395ProSer: 2.395 ± 0.04
2.227ProThr: 2.227 ± 0.04
2.566ProVal: 2.566 ± 0.046
0.416ProTrp: 0.416 ± 0.018
1.53ProTyr: 1.53 ± 0.033
0.0ProXaa: 0.0 ± 0.0
Gln
2.962GlnAla: 2.962 ± 0.053
0.177GlnCys: 0.177 ± 0.012
2.059GlnAsp: 2.059 ± 0.042
2.507GlnGlu: 2.507 ± 0.044
1.701GlnPhe: 1.701 ± 0.033
2.314GlnGly: 2.314 ± 0.046
1.03GlnHis: 1.03 ± 0.029
2.566GlnIle: 2.566 ± 0.05
2.438GlnLys: 2.438 ± 0.045
4.002GlnLeu: 4.002 ± 0.069
0.933GlnMet: 0.933 ± 0.027
1.995GlnAsn: 1.995 ± 0.037
1.36GlnPro: 1.36 ± 0.033
2.272GlnGln: 2.272 ± 0.052
1.971GlnArg: 1.971 ± 0.039
2.229GlnSer: 2.229 ± 0.047
2.15GlnThr: 2.15 ± 0.039
2.412GlnVal: 2.412 ± 0.049
0.479GlnTrp: 0.479 ± 0.021
1.643GlnTyr: 1.643 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
3.079ArgAla: 3.079 ± 0.044
0.245ArgCys: 0.245 ± 0.015
2.44ArgAsp: 2.44 ± 0.046
2.778ArgGlu: 2.778 ± 0.049
2.374ArgPhe: 2.374 ± 0.047
2.609ArgGly: 2.609 ± 0.047
0.841ArgHis: 0.841 ± 0.022
3.2ArgIle: 3.2 ± 0.042
3.048ArgLys: 3.048 ± 0.047
4.413ArgLeu: 4.413 ± 0.067
1.153ArgMet: 1.153 ± 0.03
2.618ArgAsn: 2.618 ± 0.048
1.583ArgPro: 1.583 ± 0.031
1.758ArgGln: 1.758 ± 0.035
1.977ArgArg: 1.977 ± 0.047
2.778ArgSer: 2.778 ± 0.043
2.338ArgThr: 2.338 ± 0.043
2.952ArgVal: 2.952 ± 0.048
0.656ArgTrp: 0.656 ± 0.024
2.288ArgTyr: 2.288 ± 0.044
0.0ArgXaa: 0.0 ± 0.0
Ser
4.87SerAla: 4.87 ± 0.069
0.589SerCys: 0.589 ± 0.025
3.202SerAsp: 3.202 ± 0.047
3.335SerGlu: 3.335 ± 0.049
3.739SerPhe: 3.739 ± 0.065
4.744SerGly: 4.744 ± 0.066
1.115SerHis: 1.115 ± 0.026
4.697SerIle: 4.697 ± 0.058
3.82SerLys: 3.82 ± 0.06
6.515SerLeu: 6.515 ± 0.076
1.454SerMet: 1.454 ± 0.036
3.275SerAsn: 3.275 ± 0.057
2.35SerPro: 2.35 ± 0.045
2.067SerGln: 2.067 ± 0.042
2.869SerArg: 2.869 ± 0.051
4.555SerSer: 4.555 ± 0.072
3.718SerThr: 3.718 ± 0.055
4.262SerVal: 4.262 ± 0.059
0.84SerTrp: 0.84 ± 0.03
2.881SerTyr: 2.881 ± 0.052
0.0SerXaa: 0.0 ± 0.0
Thr
4.492ThrAla: 4.492 ± 0.064
0.32ThrCys: 0.32 ± 0.016
3.125ThrAsp: 3.125 ± 0.046
2.953ThrGlu: 2.953 ± 0.049
2.925ThrPhe: 2.925 ± 0.055
4.086ThrGly: 4.086 ± 0.067
1.015ThrHis: 1.015 ± 0.028
3.982ThrIle: 3.982 ± 0.054
3.085ThrLys: 3.085 ± 0.05
5.483ThrLeu: 5.483 ± 0.07
1.032ThrMet: 1.032 ± 0.024
2.675ThrAsn: 2.675 ± 0.051
2.234ThrPro: 2.234 ± 0.037
1.879ThrGln: 1.879 ± 0.038
2.022ThrArg: 2.022 ± 0.04
3.486ThrSer: 3.486 ± 0.052
3.131ThrThr: 3.131 ± 0.057
3.785ThrVal: 3.785 ± 0.054
0.598ThrTrp: 0.598 ± 0.021
2.245ThrTyr: 2.245 ± 0.046
0.0ThrXaa: 0.0 ± 0.0
Val
4.996ValAla: 4.996 ± 0.065
0.55ValCys: 0.55 ± 0.022
4.087ValAsp: 4.087 ± 0.051
3.862ValGlu: 3.862 ± 0.054
3.18ValPhe: 3.18 ± 0.049
4.371ValGly: 4.371 ± 0.07
1.188ValHis: 1.188 ± 0.031
4.226ValIle: 4.226 ± 0.067
3.994ValLys: 3.994 ± 0.062
6.409ValLeu: 6.409 ± 0.076
1.433ValMet: 1.433 ± 0.032
3.44ValAsn: 3.44 ± 0.057
2.449ValPro: 2.449 ± 0.042
2.381ValGln: 2.381 ± 0.047
2.821ValArg: 2.821 ± 0.047
4.573ValSer: 4.573 ± 0.068
3.358ValThr: 3.358 ± 0.05
4.615ValVal: 4.615 ± 0.072
0.72ValTrp: 0.72 ± 0.023
2.466ValTyr: 2.466 ± 0.045
0.0ValXaa: 0.0 ± 0.0
Trp
0.786TrpAla: 0.786 ± 0.03
0.101TrpCys: 0.101 ± 0.008
0.67TrpAsp: 0.67 ± 0.024
0.727TrpGlu: 0.727 ± 0.025
0.557TrpPhe: 0.557 ± 0.021
0.894TrpGly: 0.894 ± 0.028
0.239TrpHis: 0.239 ± 0.013
0.79TrpIle: 0.79 ± 0.029
0.833TrpLys: 0.833 ± 0.027
1.115TrpLeu: 1.115 ± 0.031
0.364TrpMet: 0.364 ± 0.017
0.735TrpAsn: 0.735 ± 0.024
0.365TrpPro: 0.365 ± 0.019
0.547TrpGln: 0.547 ± 0.024
0.612TrpArg: 0.612 ± 0.02
0.769TrpSer: 0.769 ± 0.023
0.672TrpThr: 0.672 ± 0.025
0.696TrpVal: 0.696 ± 0.024
0.199TrpTrp: 0.199 ± 0.012
0.464TrpTyr: 0.464 ± 0.02
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.11TyrAla: 3.11 ± 0.053
0.32TyrCys: 0.32 ± 0.015
2.377TyrAsp: 2.377 ± 0.048
2.174TyrGlu: 2.174 ± 0.042
2.271TyrPhe: 2.271 ± 0.043
2.831TyrGly: 2.831 ± 0.047
0.849TyrHis: 0.849 ± 0.03
2.483TyrIle: 2.483 ± 0.042
2.379TyrLys: 2.379 ± 0.04
3.908TyrLeu: 3.908 ± 0.057
0.861TyrMet: 0.861 ± 0.025
2.265TyrAsn: 2.265 ± 0.045
1.664TyrPro: 1.664 ± 0.037
1.705TyrGln: 1.705 ± 0.041
2.066TyrArg: 2.066 ± 0.04
2.629TyrSer: 2.629 ± 0.054
2.286TyrThr: 2.286 ± 0.044
2.432TyrVal: 2.432 ± 0.044
0.542TyrTrp: 0.542 ± 0.019
1.841TyrTyr: 1.841 ± 0.043
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3969 proteins (1348934 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski