Amino acid dipepetide frequency for Borna disease virus (strain V) (BDV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.542AlaAla: 6.542 ± 1.385
0.569AlaCys: 0.569 ± 0.365
3.413AlaAsp: 3.413 ± 0.666
5.119AlaGlu: 5.119 ± 1.437
2.275AlaPhe: 2.275 ± 0.913
3.413AlaGly: 3.413 ± 0.931
0.284AlaHis: 0.284 ± 0.183
4.835AlaIle: 4.835 ± 1.394
3.129AlaLys: 3.129 ± 0.96
7.964AlaLeu: 7.964 ± 2.857
0.853AlaMet: 0.853 ± 0.348
1.422AlaAsn: 1.422 ± 0.474
3.982AlaPro: 3.982 ± 1.687
1.991AlaGln: 1.991 ± 0.605
5.404AlaArg: 5.404 ± 1.099
7.395AlaSer: 7.395 ± 1.794
3.697AlaThr: 3.697 ± 0.911
4.266AlaVal: 4.266 ± 0.472
1.422AlaTrp: 1.422 ± 1.363
1.991AlaTyr: 1.991 ± 0.338
0.0AlaXaa: 0.0 ± 0.0
Cys
0.853CysAla: 0.853 ± 0.358
1.138CysCys: 1.138 ± 0.461
1.138CysAsp: 1.138 ± 0.526
0.853CysGlu: 0.853 ± 0.649
0.569CysPhe: 0.569 ± 0.365
0.569CysGly: 0.569 ± 0.365
1.138CysHis: 1.138 ± 0.621
0.284CysIle: 0.284 ± 0.375
0.853CysLys: 0.853 ± 0.358
4.551CysLeu: 4.551 ± 1.526
0.569CysMet: 0.569 ± 0.531
1.138CysAsn: 1.138 ± 1.004
0.853CysPro: 0.853 ± 0.548
0.284CysGln: 0.284 ± 0.183
0.853CysArg: 0.853 ± 0.649
1.991CysSer: 1.991 ± 1.368
0.569CysThr: 0.569 ± 0.365
0.853CysVal: 0.853 ± 0.358
0.569CysTrp: 0.569 ± 0.365
0.569CysTyr: 0.569 ± 0.365
0.0CysXaa: 0.0 ± 0.0
Asp
3.129AspAla: 3.129 ± 1.031
1.422AspCys: 1.422 ± 0.645
1.138AspAsp: 1.138 ± 0.561
2.844AspGlu: 2.844 ± 1.334
2.56AspPhe: 2.56 ± 1.153
1.706AspGly: 1.706 ± 0.283
1.706AspHis: 1.706 ± 0.671
4.551AspIle: 4.551 ± 0.922
0.853AspLys: 0.853 ± 0.493
7.11AspLeu: 7.11 ± 1.006
1.991AspMet: 1.991 ± 0.662
0.853AspAsn: 0.853 ± 0.548
4.835AspPro: 4.835 ± 0.597
3.697AspGln: 3.697 ± 1.71
2.275AspArg: 2.275 ± 0.633
3.697AspSer: 3.697 ± 1.249
2.275AspThr: 2.275 ± 0.765
0.569AspVal: 0.569 ± 0.446
1.138AspTrp: 1.138 ± 0.39
2.275AspTyr: 2.275 ± 0.777
0.0AspXaa: 0.0 ± 0.0
Glu
3.697GluAla: 3.697 ± 0.91
1.422GluCys: 1.422 ± 0.642
3.982GluAsp: 3.982 ± 1.285
3.697GluGlu: 3.697 ± 1.034
2.844GluPhe: 2.844 ± 0.577
1.706GluGly: 1.706 ± 0.709
0.0GluHis: 0.0 ± 0.0
4.835GluIle: 4.835 ± 1.589
3.413GluLys: 3.413 ± 0.931
6.826GluLeu: 6.826 ± 1.109
1.138GluMet: 1.138 ± 0.411
1.991GluAsn: 1.991 ± 1.478
2.275GluPro: 2.275 ± 1.007
3.129GluGln: 3.129 ± 0.862
1.991GluArg: 1.991 ± 1.032
3.697GluSer: 3.697 ± 0.939
3.697GluThr: 3.697 ± 1.251
3.413GluVal: 3.413 ± 0.362
0.853GluTrp: 0.853 ± 0.543
1.422GluTyr: 1.422 ± 0.336
0.0GluXaa: 0.0 ± 0.0
Phe
1.991PheAla: 1.991 ± 0.947
0.284PheCys: 0.284 ± 0.183
1.422PheAsp: 1.422 ± 0.645
3.129PheGlu: 3.129 ± 0.388
1.706PhePhe: 1.706 ± 0.791
1.138PheGly: 1.138 ± 1.448
1.422PheHis: 1.422 ± 0.433
1.138PheIle: 1.138 ± 0.731
0.569PheLys: 0.569 ± 0.531
6.542PheLeu: 6.542 ± 2.389
1.138PheMet: 1.138 ± 0.859
2.275PheAsn: 2.275 ± 0.66
2.275PhePro: 2.275 ± 0.706
1.706PheGln: 1.706 ± 0.881
2.56PheArg: 2.56 ± 1.312
2.275PheSer: 2.275 ± 0.66
1.422PheThr: 1.422 ± 0.73
2.844PheVal: 2.844 ± 0.812
0.284PheTrp: 0.284 ± 0.183
1.706PheTyr: 1.706 ± 0.945
0.0PheXaa: 0.0 ± 0.0
Gly
4.551GlyAla: 4.551 ± 1.614
1.991GlyCys: 1.991 ± 0.961
2.275GlyAsp: 2.275 ± 0.933
4.835GlyGlu: 4.835 ± 2.271
1.706GlyPhe: 1.706 ± 0.709
3.413GlyGly: 3.413 ± 0.719
2.275GlyHis: 2.275 ± 0.373
1.991GlyIle: 1.991 ± 0.338
1.991GlyLys: 1.991 ± 0.814
5.119GlyLeu: 5.119 ± 0.966
0.569GlyMet: 0.569 ± 0.365
0.569GlyAsn: 0.569 ± 0.347
3.129GlyPro: 3.129 ± 1.583
1.991GlyGln: 1.991 ± 0.677
3.982GlyArg: 3.982 ± 1.234
4.551GlySer: 4.551 ± 1.699
4.266GlyThr: 4.266 ± 2.238
6.542GlyVal: 6.542 ± 1.028
0.853GlyTrp: 0.853 ± 0.854
2.275GlyTyr: 2.275 ± 0.463
0.0GlyXaa: 0.0 ± 0.0
His
2.56HisAla: 2.56 ± 0.783
0.853HisCys: 0.853 ± 0.616
1.138HisAsp: 1.138 ± 0.423
1.422HisGlu: 1.422 ± 1.092
0.569HisPhe: 0.569 ± 0.365
1.422HisGly: 1.422 ± 0.948
1.138HisHis: 1.138 ± 0.731
1.422HisIle: 1.422 ± 0.627
0.853HisLys: 0.853 ± 0.358
2.275HisLeu: 2.275 ± 1.136
0.284HisMet: 0.284 ± 0.183
0.569HisAsn: 0.569 ± 0.365
2.844HisPro: 2.844 ± 0.905
0.284HisGln: 0.284 ± 0.183
0.853HisArg: 0.853 ± 0.358
2.844HisSer: 2.844 ± 1.144
1.991HisThr: 1.991 ± 0.906
0.569HisVal: 0.569 ± 0.365
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.413IleAla: 3.413 ± 1.581
0.569IleCys: 0.569 ± 0.31
3.982IleAsp: 3.982 ± 1.262
2.844IleGlu: 2.844 ± 1.031
1.138IlePhe: 1.138 ± 0.39
4.835IleGly: 4.835 ± 1.589
0.569IleHis: 0.569 ± 0.365
5.119IleIle: 5.119 ± 1.964
5.404IleLys: 5.404 ± 2.545
4.266IleLeu: 4.266 ± 1.109
1.138IleMet: 1.138 ± 0.39
3.982IleAsn: 3.982 ± 0.77
2.844IlePro: 2.844 ± 1.099
2.56IleGln: 2.56 ± 0.633
6.542IleArg: 6.542 ± 0.791
4.835IleSer: 4.835 ± 1.724
1.991IleThr: 1.991 ± 0.947
2.275IleVal: 2.275 ± 0.777
0.0IleTrp: 0.0 ± 0.0
1.991IleTyr: 1.991 ± 0.741
0.0IleXaa: 0.0 ± 0.0
Lys
2.275LysAla: 2.275 ± 0.463
0.0LysCys: 0.0 ± 0.0
2.275LysAsp: 2.275 ± 1.518
4.266LysGlu: 4.266 ± 2.475
1.138LysPhe: 1.138 ± 1.063
1.706LysGly: 1.706 ± 0.58
0.853LysHis: 0.853 ± 0.898
1.706LysIle: 1.706 ± 0.785
2.844LysLys: 2.844 ± 1.099
6.826LysLeu: 6.826 ± 1.509
1.138LysMet: 1.138 ± 0.39
1.422LysAsn: 1.422 ± 0.697
0.853LysPro: 0.853 ± 0.358
0.853LysGln: 0.853 ± 0.548
2.275LysArg: 2.275 ± 0.56
3.413LysSer: 3.413 ± 2.193
4.835LysThr: 4.835 ± 1.327
3.129LysVal: 3.129 ± 1.141
0.284LysTrp: 0.284 ± 0.183
1.422LysTyr: 1.422 ± 0.692
0.0LysXaa: 0.0 ± 0.0
Leu
7.679LeuAla: 7.679 ± 1.621
2.844LeuCys: 2.844 ± 0.717
5.404LeuAsp: 5.404 ± 2.139
6.542LeuGlu: 6.542 ± 0.773
2.56LeuPhe: 2.56 ± 0.998
6.257LeuGly: 6.257 ± 1.103
1.991LeuHis: 1.991 ± 0.556
5.688LeuIle: 5.688 ± 0.588
5.404LeuLys: 5.404 ± 1.033
13.367LeuLeu: 13.367 ± 1.71
2.56LeuMet: 2.56 ± 0.932
5.119LeuAsn: 5.119 ± 2.679
8.248LeuPro: 8.248 ± 0.627
4.835LeuGln: 4.835 ± 0.95
5.119LeuArg: 5.119 ± 1.275
8.248LeuSer: 8.248 ± 0.739
7.395LeuThr: 7.395 ± 1.002
8.817LeuVal: 8.817 ± 1.207
0.853LeuTrp: 0.853 ± 0.548
4.835LeuTyr: 4.835 ± 1.374
0.0LeuXaa: 0.0 ± 0.0
Met
2.56MetAla: 2.56 ± 0.759
0.284MetCys: 0.284 ± 0.183
2.844MetAsp: 2.844 ± 0.866
1.991MetGlu: 1.991 ± 1.333
1.706MetPhe: 1.706 ± 1.065
0.569MetGly: 0.569 ± 0.365
0.0MetHis: 0.0 ± 0.0
2.275MetIle: 2.275 ± 1.228
1.991MetLys: 1.991 ± 1.333
1.422MetLeu: 1.422 ± 0.783
1.991MetMet: 1.991 ± 1.333
0.284MetAsn: 0.284 ± 0.47
1.138MetPro: 1.138 ± 0.496
0.853MetGln: 0.853 ± 0.358
0.569MetArg: 0.569 ± 0.365
1.991MetSer: 1.991 ± 0.717
1.706MetThr: 1.706 ± 0.283
0.853MetVal: 0.853 ± 0.548
0.284MetTrp: 0.284 ± 0.362
0.284MetTyr: 0.284 ± 0.362
0.0MetXaa: 0.0 ± 0.0
Asn
2.844AsnAla: 2.844 ± 0.695
0.284AsnCys: 0.284 ± 0.183
1.422AsnAsp: 1.422 ± 0.509
0.569AsnGlu: 0.569 ± 0.31
0.284AsnPhe: 0.284 ± 0.183
2.275AsnGly: 2.275 ± 1.458
1.138AsnHis: 1.138 ± 1.004
2.844AsnIle: 2.844 ± 1.385
0.853AsnLys: 0.853 ± 0.854
2.56AsnLeu: 2.56 ± 0.998
1.991AsnMet: 1.991 ± 0.357
0.569AsnAsn: 0.569 ± 0.31
2.844AsnPro: 2.844 ± 0.659
1.138AsnGln: 1.138 ± 0.595
1.991AsnArg: 1.991 ± 0.414
1.991AsnSer: 1.991 ± 1.273
1.138AsnThr: 1.138 ± 0.621
2.275AsnVal: 2.275 ± 1.265
0.284AsnTrp: 0.284 ± 0.362
0.569AsnTyr: 0.569 ± 0.31
0.0AsnXaa: 0.0 ± 0.0
Pro
5.119ProAla: 5.119 ± 0.7
1.422ProCys: 1.422 ± 0.914
2.844ProAsp: 2.844 ± 0.828
2.56ProGlu: 2.56 ± 0.873
2.56ProPhe: 2.56 ± 0.466
5.404ProGly: 5.404 ± 2.34
2.844ProHis: 2.844 ± 0.866
1.422ProIle: 1.422 ± 0.522
1.706ProLys: 1.706 ± 0.719
3.129ProLeu: 3.129 ± 1.137
1.138ProMet: 1.138 ± 1.312
0.853ProAsn: 0.853 ± 0.429
3.413ProPro: 3.413 ± 0.48
2.56ProGln: 2.56 ± 0.778
4.835ProArg: 4.835 ± 1.748
5.119ProSer: 5.119 ± 1.55
3.697ProThr: 3.697 ± 0.617
3.982ProVal: 3.982 ± 0.731
1.422ProTrp: 1.422 ± 0.433
2.275ProTyr: 2.275 ± 0.953
0.0ProXaa: 0.0 ± 0.0
Gln
1.138GlnAla: 1.138 ± 0.477
0.284GlnCys: 0.284 ± 0.362
1.422GlnAsp: 1.422 ± 0.433
1.138GlnGlu: 1.138 ± 0.737
1.706GlnPhe: 1.706 ± 0.619
2.56GlnGly: 2.56 ± 1.312
0.569GlnHis: 0.569 ± 0.365
2.56GlnIle: 2.56 ± 0.783
1.138GlnLys: 1.138 ± 0.731
5.688GlnLeu: 5.688 ± 1.625
1.422GlnMet: 1.422 ± 0.948
0.853GlnAsn: 0.853 ± 0.429
2.844GlnPro: 2.844 ± 0.659
0.853GlnGln: 0.853 ± 0.649
2.56GlnArg: 2.56 ± 1.143
2.844GlnSer: 2.844 ± 0.747
3.129GlnThr: 3.129 ± 1.048
1.991GlnVal: 1.991 ± 0.789
0.284GlnTrp: 0.284 ± 0.183
0.853GlnTyr: 0.853 ± 0.429
0.0GlnXaa: 0.0 ± 0.0
Arg
2.844ArgAla: 2.844 ± 1.168
1.138ArgCys: 1.138 ± 0.588
3.697ArgAsp: 3.697 ± 1.019
3.697ArgGlu: 3.697 ± 1.111
2.275ArgPhe: 2.275 ± 0.833
4.835ArgGly: 4.835 ± 1.287
1.138ArgHis: 1.138 ± 0.39
4.266ArgIle: 4.266 ± 1.437
2.275ArgLys: 2.275 ± 0.8
7.395ArgLeu: 7.395 ± 2.03
0.569ArgMet: 0.569 ± 0.365
1.422ArgAsn: 1.422 ± 0.94
5.688ArgPro: 5.688 ± 1.208
1.991ArgGln: 1.991 ± 0.677
6.826ArgArg: 6.826 ± 3.333
3.982ArgSer: 3.982 ± 0.811
1.991ArgThr: 1.991 ± 0.535
1.991ArgVal: 1.991 ± 0.823
1.138ArgTrp: 1.138 ± 0.477
1.991ArgTyr: 1.991 ± 0.906
0.0ArgXaa: 0.0 ± 0.0
Ser
8.248SerAla: 8.248 ± 2.057
2.56SerCys: 2.56 ± 1.253
4.835SerAsp: 4.835 ± 0.951
1.138SerGlu: 1.138 ± 0.477
5.119SerPhe: 5.119 ± 1.155
3.697SerGly: 3.697 ± 1.051
2.844SerHis: 2.844 ± 0.905
4.551SerIle: 4.551 ± 0.685
3.982SerLys: 3.982 ± 0.857
10.239SerLeu: 10.239 ± 0.716
1.991SerMet: 1.991 ± 1.44
1.422SerAsn: 1.422 ± 0.509
1.991SerPro: 1.991 ± 0.583
1.706SerGln: 1.706 ± 0.716
5.404SerArg: 5.404 ± 1.615
8.817SerSer: 8.817 ± 0.97
4.835SerThr: 4.835 ± 1.248
4.551SerVal: 4.551 ± 1.768
1.138SerTrp: 1.138 ± 0.477
3.697SerTyr: 3.697 ± 1.507
0.0SerXaa: 0.0 ± 0.0
Thr
3.413ThrAla: 3.413 ± 1.341
1.138ThrCys: 1.138 ± 0.477
3.697ThrAsp: 3.697 ± 0.694
2.844ThrGlu: 2.844 ± 0.767
1.991ThrPhe: 1.991 ± 0.947
4.551ThrGly: 4.551 ± 0.771
1.138ThrHis: 1.138 ± 0.731
5.404ThrIle: 5.404 ± 1.017
1.138ThrLys: 1.138 ± 0.529
7.11ThrLeu: 7.11 ± 0.692
3.413ThrMet: 3.413 ± 1.341
1.422ThrAsn: 1.422 ± 0.951
3.982ThrPro: 3.982 ± 1.371
2.56ThrGln: 2.56 ± 0.974
1.422ThrArg: 1.422 ± 0.57
4.551ThrSer: 4.551 ± 1.388
6.257ThrThr: 6.257 ± 2.285
4.551ThrVal: 4.551 ± 1.194
0.853ThrTrp: 0.853 ± 0.548
2.275ThrTyr: 2.275 ± 0.808
0.0ThrXaa: 0.0 ± 0.0
Val
4.266ValAla: 4.266 ± 1.0
0.569ValCys: 0.569 ± 0.365
3.129ValAsp: 3.129 ± 1.043
3.982ValGlu: 3.982 ± 1.414
2.56ValPhe: 2.56 ± 0.429
5.973ValGly: 5.973 ± 0.713
1.991ValHis: 1.991 ± 0.906
3.413ValIle: 3.413 ± 0.848
3.413ValLys: 3.413 ± 0.591
4.835ValLeu: 4.835 ± 1.461
1.138ValMet: 1.138 ± 0.477
1.991ValAsn: 1.991 ± 0.947
2.275ValPro: 2.275 ± 0.594
1.138ValGln: 1.138 ± 0.477
2.844ValArg: 2.844 ± 1.02
5.973ValSer: 5.973 ± 1.921
5.688ValThr: 5.688 ± 0.865
5.119ValVal: 5.119 ± 0.941
0.284ValTrp: 0.284 ± 0.362
1.138ValTyr: 1.138 ± 0.595
0.0ValXaa: 0.0 ± 0.0
Trp
0.569TrpAla: 0.569 ± 0.31
0.284TrpCys: 0.284 ± 0.183
0.569TrpAsp: 0.569 ± 0.617
0.853TrpGlu: 0.853 ± 0.358
0.569TrpPhe: 0.569 ± 0.724
0.569TrpGly: 0.569 ± 0.31
0.0TrpHis: 0.0 ± 0.0
0.853TrpIle: 0.853 ± 0.429
0.569TrpLys: 0.569 ± 0.365
1.706TrpLeu: 1.706 ± 0.931
0.0TrpMet: 0.0 ± 0.0
0.284TrpAsn: 0.284 ± 0.362
0.569TrpPro: 0.569 ± 0.446
0.853TrpGln: 0.853 ± 0.649
0.284TrpArg: 0.284 ± 0.183
1.706TrpSer: 1.706 ± 0.538
0.284TrpThr: 0.284 ± 0.183
1.706TrpVal: 1.706 ± 0.283
0.0TrpTrp: 0.0 ± 0.0
0.569TrpTyr: 0.569 ± 0.365
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.275TyrAla: 2.275 ± 0.592
1.138TyrCys: 1.138 ± 0.621
0.0TyrAsp: 0.0 ± 0.0
1.706TyrGlu: 1.706 ± 0.858
1.991TyrPhe: 1.991 ± 0.966
2.275TyrGly: 2.275 ± 0.463
0.853TyrHis: 0.853 ± 0.649
1.138TyrIle: 1.138 ± 0.621
1.138TyrLys: 1.138 ± 0.595
4.835TyrLeu: 4.835 ± 0.875
0.284TyrMet: 0.284 ± 0.47
1.422TyrAsn: 1.422 ± 0.645
1.706TyrPro: 1.706 ± 0.489
0.853TyrGln: 0.853 ± 0.358
2.56TyrArg: 2.56 ± 0.823
2.844TyrSer: 2.844 ± 1.253
2.844TyrThr: 2.844 ± 1.42
1.422TyrVal: 1.422 ± 0.73
0.853TyrTrp: 0.853 ± 0.616
1.138TyrTyr: 1.138 ± 0.477
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (3517 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski