Amino acid dipepetide frequency for Chrysosporum ovalisporum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.527AlaAla: 7.527 ± 0.116	0.789AlaCys: 0.789 ± 0.028	3.818AlaAsp: 3.818 ± 0.064	5.234AlaGlu: 5.234 ± 0.082	2.755AlaPhe: 2.755 ± 0.053	5.462AlaGly: 5.462 ± 0.09	1.491AlaHis: 1.491 ± 0.042	6.477AlaIle: 6.477 ± 0.093	4.109AlaLys: 4.109 ± 0.072	8.484AlaLeu: 8.484 ± 0.121	1.927AlaMet: 1.927 ± 0.054	3.352AlaAsn: 3.352 ± 0.075	2.847AlaPro: 2.847 ± 0.057	4.171AlaGln: 4.171 ± 0.083	3.687AlaArg: 3.687 ± 0.072	4.613AlaSer: 4.613 ± 0.07	4.467AlaThr: 4.467 ± 0.065	5.671AlaVal: 5.671 ± 0.088	1.012AlaTrp: 1.012 ± 0.038	2.24AlaTyr: 2.24 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.699CysAla: 0.699 ± 0.027	0.182CysCys: 0.182 ± 0.016	0.553CysAsp: 0.553 ± 0.02	0.541CysGlu: 0.541 ± 0.025	0.427CysPhe: 0.427 ± 0.022	0.866CysGly: 0.866 ± 0.033	0.326CysHis: 0.326 ± 0.023	0.588CysIle: 0.588 ± 0.024	0.343CysLys: 0.343 ± 0.017	1.11CysLeu: 1.11 ± 0.035	0.175CysMet: 0.175 ± 0.013	0.411CysAsn: 0.411 ± 0.024	0.595CysPro: 0.595 ± 0.028	0.645CysGln: 0.645 ± 0.028	0.53CysArg: 0.53 ± 0.025	0.606CysSer: 0.606 ± 0.026	0.497CysThr: 0.497 ± 0.022	0.599CysVal: 0.599 ± 0.023	0.149CysTrp: 0.149 ± 0.011	0.351CysTyr: 0.351 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	3.432AspAla: 3.432 ± 0.06	0.537AspCys: 0.537 ± 0.025	1.951AspAsp: 1.951 ± 0.057	2.825AspGlu: 2.825 ± 0.069	2.22AspPhe: 2.22 ± 0.05	3.014AspGly: 3.014 ± 0.07	0.844AspHis: 0.844 ± 0.031	3.431AspIle: 3.431 ± 0.058	2.171AspLys: 2.171 ± 0.057	5.566AspLeu: 5.566 ± 0.093	0.887AspMet: 0.887 ± 0.034	1.869AspAsn: 1.869 ± 0.053	2.424AspPro: 2.424 ± 0.061	1.894AspGln: 1.894 ± 0.051	2.491AspArg: 2.491 ± 0.057	2.704AspSer: 2.704 ± 0.052	2.502AspThr: 2.502 ± 0.047	3.001AspVal: 3.001 ± 0.058	0.834AspTrp: 0.834 ± 0.029	1.775AspTyr: 1.775 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	5.0GluAla: 5.0 ± 0.076	0.457GluCys: 0.457 ± 0.021	2.593GluAsp: 2.593 ± 0.06	3.919GluGlu: 3.919 ± 0.089	2.419GluPhe: 2.419 ± 0.045	3.088GluGly: 3.088 ± 0.056	1.101GluHis: 1.101 ± 0.036	5.0GluIle: 5.0 ± 0.078	3.599GluLys: 3.599 ± 0.077	6.974GluLeu: 6.974 ± 0.104	1.338GluMet: 1.338 ± 0.042	2.918GluAsn: 2.918 ± 0.057	2.48GluPro: 2.48 ± 0.059	3.429GluGln: 3.429 ± 0.067	3.242GluArg: 3.242 ± 0.059	3.2GluSer: 3.2 ± 0.061	3.47GluThr: 3.47 ± 0.058	4.221GluVal: 4.221 ± 0.065	0.764GluTrp: 0.764 ± 0.031	1.802GluTyr: 1.802 ± 0.056	0.0GluXaa: 0.0 ± 0.0
Phe	3.172PheAla: 3.172 ± 0.066	0.569PheCys: 0.569 ± 0.027	2.175PheAsp: 2.175 ± 0.049	1.99PheGlu: 1.99 ± 0.047	1.65PhePhe: 1.65 ± 0.043	2.996PheGly: 2.996 ± 0.062	0.877PheHis: 0.877 ± 0.03	2.355PheIle: 2.355 ± 0.058	1.518PheLys: 1.518 ± 0.044	4.156PheLeu: 4.156 ± 0.08	0.71PheMet: 0.71 ± 0.025	1.758PheAsn: 1.758 ± 0.044	1.898PhePro: 1.898 ± 0.044	1.854PheGln: 1.854 ± 0.037	1.79PheArg: 1.79 ± 0.043	2.726PheSer: 2.726 ± 0.048	2.346PheThr: 2.346 ± 0.054	2.44PheVal: 2.44 ± 0.055	0.714PheTrp: 0.714 ± 0.03	1.296PheTyr: 1.296 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	4.892GlyAla: 4.892 ± 0.1	0.815GlyCys: 0.815 ± 0.028	3.208GlyAsp: 3.208 ± 0.073	4.236GlyGlu: 4.236 ± 0.083	3.076GlyPhe: 3.076 ± 0.064	4.999GlyGly: 4.999 ± 0.086	1.386GlyHis: 1.386 ± 0.042	5.274GlyIle: 5.274 ± 0.09	4.184GlyLys: 4.184 ± 0.057	7.201GlyLeu: 7.201 ± 0.09	1.609GlyMet: 1.609 ± 0.04	3.008GlyAsn: 3.008 ± 0.075	1.559GlyPro: 1.559 ± 0.053	2.974GlyGln: 2.974 ± 0.058	3.423GlyArg: 3.423 ± 0.061	4.118GlySer: 4.118 ± 0.065	3.873GlyThr: 3.873 ± 0.066	5.077GlyVal: 5.077 ± 0.083	1.108GlyTrp: 1.108 ± 0.039	2.382GlyTyr: 2.382 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	1.044HisAla: 1.044 ± 0.033	0.301HisCys: 0.301 ± 0.018	0.812HisAsp: 0.812 ± 0.032	0.968HisGlu: 0.968 ± 0.031	0.804HisPhe: 0.804 ± 0.03	1.401HisGly: 1.401 ± 0.04	0.75HisHis: 0.75 ± 0.037	1.289HisIle: 1.289 ± 0.038	0.912HisLys: 0.912 ± 0.029	2.515HisLeu: 2.515 ± 0.058	0.313HisMet: 0.313 ± 0.02	0.938HisAsn: 0.938 ± 0.032	1.5HisPro: 1.5 ± 0.035	1.378HisGln: 1.378 ± 0.042	1.367HisArg: 1.367 ± 0.04	1.357HisSer: 1.357 ± 0.037	1.061HisThr: 1.061 ± 0.034	0.899HisVal: 0.899 ± 0.029	0.43HisTrp: 0.43 ± 0.022	0.718HisTyr: 0.718 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.895IleAla: 6.895 ± 0.099	0.771IleCys: 0.771 ± 0.033	3.602IleAsp: 3.602 ± 0.065	3.844IleGlu: 3.844 ± 0.064	2.764IlePhe: 2.764 ± 0.063	4.659IleGly: 4.659 ± 0.075	1.391IleHis: 1.391 ± 0.038	4.197IleIle: 4.197 ± 0.084	3.127IleLys: 3.127 ± 0.055	7.044IleLeu: 7.044 ± 0.098	0.982IleMet: 0.982 ± 0.033	3.178IleAsn: 3.178 ± 0.064	3.889IlePro: 3.889 ± 0.074	3.091IleGln: 3.091 ± 0.051	3.132IleArg: 3.132 ± 0.057	4.614IleSer: 4.614 ± 0.075	4.12IleThr: 4.12 ± 0.07	4.418IleVal: 4.418 ± 0.08	0.876IleTrp: 0.876 ± 0.035	2.033IleTyr: 2.033 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	3.79LysAla: 3.79 ± 0.068	0.299LysCys: 0.299 ± 0.017	1.983LysAsp: 1.983 ± 0.052	2.692LysGlu: 2.692 ± 0.054	1.871LysPhe: 1.871 ± 0.044	2.594LysGly: 2.594 ± 0.058	0.862LysHis: 0.862 ± 0.03	3.81LysIle: 3.81 ± 0.075	2.403LysLys: 2.403 ± 0.058	5.577LysLeu: 5.577 ± 0.085	0.919LysMet: 0.919 ± 0.028	2.261LysAsn: 2.261 ± 0.052	2.501LysPro: 2.501 ± 0.055	2.622LysGln: 2.622 ± 0.053	2.173LysArg: 2.173 ± 0.054	3.055LysSer: 3.055 ± 0.058	2.943LysThr: 2.943 ± 0.055	3.307LysVal: 3.307 ± 0.057	0.5LysTrp: 0.5 ± 0.023	1.568LysTyr: 1.568 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	9.903LeuAla: 9.903 ± 0.117	1.057LeuCys: 1.057 ± 0.032	5.081LeuAsp: 5.081 ± 0.08	6.998LeuGlu: 6.998 ± 0.089	3.882LeuPhe: 3.882 ± 0.077	7.981LeuGly: 7.981 ± 0.101	2.12LeuHis: 2.12 ± 0.048	7.043LeuIle: 7.043 ± 0.095	5.372LeuLys: 5.372 ± 0.074	11.284LeuLeu: 11.284 ± 0.145	2.249LeuMet: 2.249 ± 0.058	4.561LeuAsn: 4.561 ± 0.077	5.917LeuPro: 5.917 ± 0.086	5.965LeuGln: 5.965 ± 0.101	5.469LeuArg: 5.469 ± 0.09	7.092LeuSer: 7.092 ± 0.101	6.464LeuThr: 6.464 ± 0.081	7.511LeuVal: 7.511 ± 0.102	1.395LeuTrp: 1.395 ± 0.047	2.619LeuTyr: 2.619 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	1.996MetAla: 1.996 ± 0.052	0.173MetCys: 0.173 ± 0.014	0.769MetAsp: 0.769 ± 0.027	1.087MetGlu: 1.087 ± 0.034	0.643MetPhe: 0.643 ± 0.025	1.564MetGly: 1.564 ± 0.048	0.316MetHis: 0.316 ± 0.017	1.167MetIle: 1.167 ± 0.035	0.956MetLys: 0.956 ± 0.032	1.982MetLeu: 1.982 ± 0.052	0.479MetMet: 0.479 ± 0.023	0.864MetAsn: 0.864 ± 0.031	0.932MetPro: 0.932 ± 0.031	0.912MetGln: 0.912 ± 0.032	1.042MetArg: 1.042 ± 0.035	1.356MetSer: 1.356 ± 0.042	1.4MetThr: 1.4 ± 0.035	1.456MetVal: 1.456 ± 0.035	0.165MetTrp: 0.165 ± 0.014	0.413MetTyr: 0.413 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.81AsnAla: 2.81 ± 0.055	0.543AsnCys: 0.543 ± 0.026	1.519AsnAsp: 1.519 ± 0.043	1.847AsnGlu: 1.847 ± 0.046	2.04AsnPhe: 2.04 ± 0.045	2.509AsnGly: 2.509 ± 0.052	1.098AsnHis: 1.098 ± 0.038	2.964AsnIle: 2.964 ± 0.061	1.806AsnLys: 1.806 ± 0.049	5.56AsnLeu: 5.56 ± 0.1	0.693AsnMet: 0.693 ± 0.03	2.072AsnAsn: 2.072 ± 0.059	2.932AsnPro: 2.932 ± 0.067	2.683AsnGln: 2.683 ± 0.057	2.334AsnArg: 2.334 ± 0.046	3.053AsnSer: 3.053 ± 0.065	2.267AsnThr: 2.267 ± 0.053	2.334AsnVal: 2.334 ± 0.046	0.803AsnTrp: 0.803 ± 0.032	1.634AsnTyr: 1.634 ± 0.046	0.0AsnXaa: 0.0 ± 0.0
Pro	3.13ProAla: 3.13 ± 0.064	0.419ProCys: 0.419 ± 0.022	2.824ProAsp: 2.824 ± 0.052	4.033ProGlu: 4.033 ± 0.064	1.673ProPhe: 1.673 ± 0.041	3.591ProGly: 3.591 ± 0.072	1.147ProHis: 1.147 ± 0.036	3.054ProIle: 3.054 ± 0.053	2.179ProLys: 2.179 ± 0.056	4.885ProLeu: 4.885 ± 0.074	0.853ProMet: 0.853 ± 0.027	2.128ProAsn: 2.128 ± 0.054	2.419ProPro: 2.419 ± 0.056	2.969ProGln: 2.969 ± 0.062	2.01ProArg: 2.01 ± 0.046	2.829ProSer: 2.829 ± 0.052	2.923ProThr: 2.923 ± 0.066	3.531ProVal: 3.531 ± 0.07	0.705ProTrp: 0.705 ± 0.033	1.387ProTyr: 1.387 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	4.544GlnAla: 4.544 ± 0.071	0.439GlnCys: 0.439 ± 0.022	2.17GlnAsp: 2.17 ± 0.051	3.735GlnGlu: 3.735 ± 0.069	1.753GlnPhe: 1.753 ± 0.047	3.619GlnGly: 3.619 ± 0.059	0.927GlnHis: 0.927 ± 0.034	3.742GlnIle: 3.742 ± 0.062	2.875GlnLys: 2.875 ± 0.059	5.986GlnLeu: 5.986 ± 0.112	1.094GlnMet: 1.094 ± 0.034	2.215GlnAsn: 2.215 ± 0.047	2.755GlnPro: 2.755 ± 0.054	3.729GlnGln: 3.729 ± 0.086	3.062GlnArg: 3.062 ± 0.064	2.775GlnSer: 2.775 ± 0.061	2.845GlnThr: 2.845 ± 0.058	4.009GlnVal: 4.009 ± 0.064	0.776GlnTrp: 0.776 ± 0.027	1.258GlnTyr: 1.258 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	3.189ArgAla: 3.189 ± 0.069	0.543ArgCys: 0.543 ± 0.024	2.427ArgAsp: 2.427 ± 0.051	3.252ArgGlu: 3.252 ± 0.059	2.076ArgPhe: 2.076 ± 0.045	3.096ArgGly: 3.096 ± 0.056	1.175ArgHis: 1.175 ± 0.034	3.356ArgIle: 3.356 ± 0.069	2.146ArgLys: 2.146 ± 0.042	5.919ArgLeu: 5.919 ± 0.089	0.973ArgMet: 0.973 ± 0.029	2.121ArgAsn: 2.121 ± 0.05	2.159ArgPro: 2.159 ± 0.053	3.209ArgGln: 3.209 ± 0.062	3.11ArgArg: 3.11 ± 0.073	3.034ArgSer: 3.034 ± 0.052	2.465ArgThr: 2.465 ± 0.053	3.541ArgVal: 3.541 ± 0.066	0.851ArgTrp: 0.851 ± 0.028	1.872ArgTyr: 1.872 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	4.371SerAla: 4.371 ± 0.077	0.601SerCys: 0.601 ± 0.026	2.756SerAsp: 2.756 ± 0.059	3.485SerGlu: 3.485 ± 0.062	2.451SerPhe: 2.451 ± 0.058	4.441SerGly: 4.441 ± 0.071	1.51SerHis: 1.51 ± 0.04	3.764SerIle: 3.764 ± 0.063	2.468SerLys: 2.468 ± 0.06	7.116SerLeu: 7.116 ± 0.092	1.269SerMet: 1.269 ± 0.038	2.546SerAsn: 2.546 ± 0.057	3.406SerPro: 3.406 ± 0.062	3.814SerGln: 3.814 ± 0.073	3.192SerArg: 3.192 ± 0.057	4.22SerSer: 4.22 ± 0.079	3.543SerThr: 3.543 ± 0.063	4.116SerVal: 4.116 ± 0.068	0.97SerTrp: 0.97 ± 0.033	1.783SerTyr: 1.783 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	4.961ThrAla: 4.961 ± 0.079	0.466ThrCys: 0.466 ± 0.026	2.643ThrAsp: 2.643 ± 0.063	3.308ThrGlu: 3.308 ± 0.052	1.981ThrPhe: 1.981 ± 0.047	4.423ThrGly: 4.423 ± 0.076	1.091ThrHis: 1.091 ± 0.034	3.794ThrIle: 3.794 ± 0.065	2.379ThrLys: 2.379 ± 0.051	6.159ThrLeu: 6.159 ± 0.077	0.908ThrMet: 0.908 ± 0.034	2.246ThrAsn: 2.246 ± 0.053	3.459ThrPro: 3.459 ± 0.063	2.817ThrGln: 2.817 ± 0.064	2.477ThrArg: 2.477 ± 0.055	3.625ThrSer: 3.625 ± 0.068	3.525ThrThr: 3.525 ± 0.079	4.154ThrVal: 4.154 ± 0.064	0.733ThrTrp: 0.733 ± 0.026	1.601ThrTyr: 1.601 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	5.925ValAla: 5.925 ± 0.084	0.681ValCys: 0.681 ± 0.033	3.479ValAsp: 3.479 ± 0.065	4.377ValGlu: 4.377 ± 0.081	2.626ValPhe: 2.626 ± 0.055	4.855ValGly: 4.855 ± 0.082	1.187ValHis: 1.187 ± 0.042	4.753ValIle: 4.753 ± 0.076	3.418ValLys: 3.418 ± 0.065	6.841ValLeu: 6.841 ± 0.091	1.532ValMet: 1.532 ± 0.048	3.194ValAsn: 3.194 ± 0.055	2.982ValPro: 2.982 ± 0.055	2.939ValGln: 2.939 ± 0.055	3.273ValArg: 3.273 ± 0.058	4.231ValSer: 4.231 ± 0.068	3.925ValThr: 3.925 ± 0.068	5.076ValVal: 5.076 ± 0.089	0.787ValTrp: 0.787 ± 0.03	1.944ValTyr: 1.944 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.811TrpAla: 0.811 ± 0.029	0.165TrpCys: 0.165 ± 0.012	0.625TrpAsp: 0.625 ± 0.027	0.928TrpGlu: 0.928 ± 0.037	0.563TrpPhe: 0.563 ± 0.026	1.075TrpGly: 1.075 ± 0.038	0.351TrpHis: 0.351 ± 0.021	0.854TrpIle: 0.854 ± 0.031	0.587TrpLys: 0.587 ± 0.024	2.013TrpLeu: 2.013 ± 0.053	0.319TrpMet: 0.319 ± 0.017	0.644TrpAsn: 0.644 ± 0.03	0.358TrpPro: 0.358 ± 0.023	1.223TrpGln: 1.223 ± 0.04	0.872TrpArg: 0.872 ± 0.035	0.778TrpSer: 0.778 ± 0.027	0.576TrpThr: 0.576 ± 0.024	0.909TrpVal: 0.909 ± 0.032	0.243TrpTrp: 0.243 ± 0.02	0.448TrpTyr: 0.448 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.042TyrAla: 2.042 ± 0.044	0.386TyrCys: 0.386 ± 0.02	1.384TyrAsp: 1.384 ± 0.036	1.714TyrGlu: 1.714 ± 0.043	1.314TyrPhe: 1.314 ± 0.039	2.171TyrGly: 2.171 ± 0.048	0.807TyrHis: 0.807 ± 0.032	1.717TyrIle: 1.717 ± 0.049	1.18TyrLys: 1.18 ± 0.041	3.587TyrLeu: 3.587 ± 0.062	0.44TyrMet: 0.44 ± 0.021	1.216TyrAsn: 1.216 ± 0.037	1.678TyrPro: 1.678 ± 0.039	1.992TyrGln: 1.992 ± 0.047	1.838TyrArg: 1.838 ± 0.05	1.836TyrSer: 1.836 ± 0.039	1.538TyrThr: 1.538 ± 0.045	1.757TyrVal: 1.757 ± 0.044	0.529TyrTrp: 0.529 ± 0.023	1.071TyrTyr: 1.071 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2851 proteins (968037 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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