Amino acid dipepetide frequency for Callitrichine gammaherpesvirus 3 (Marmoset lymphocryptovirus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.042AlaAla: 6.042 ± 0.758
1.289AlaCys: 1.289 ± 0.174
3.035AlaAsp: 3.035 ± 0.324
3.064AlaGlu: 3.064 ± 0.352
2.892AlaPhe: 2.892 ± 0.304
3.579AlaGly: 3.579 ± 0.338
1.489AlaHis: 1.489 ± 0.176
3.808AlaIle: 3.808 ± 0.312
2.606AlaLys: 2.606 ± 0.278
7.331AlaLeu: 7.331 ± 0.548
1.747AlaMet: 1.747 ± 0.223
2.348AlaAsn: 2.348 ± 0.272
3.436AlaPro: 3.436 ± 0.346
2.262AlaGln: 2.262 ± 0.245
3.894AlaArg: 3.894 ± 0.346
6.472AlaSer: 6.472 ± 0.426
4.925AlaThr: 4.925 ± 0.459
5.011AlaVal: 5.011 ± 0.406
1.317AlaTrp: 1.317 ± 0.231
1.947AlaTyr: 1.947 ± 0.239
0.0AlaXaa: 0.0 ± 0.0
Cys
1.689CysAla: 1.689 ± 0.26
0.659CysCys: 0.659 ± 0.17
1.088CysAsp: 1.088 ± 0.201
1.002CysGlu: 1.002 ± 0.19
1.174CysPhe: 1.174 ± 0.193
1.06CysGly: 1.06 ± 0.211
1.031CysHis: 1.031 ± 0.208
1.317CysIle: 1.317 ± 0.225
0.745CysLys: 0.745 ± 0.132
2.892CysLeu: 2.892 ± 0.385
0.63CysMet: 0.63 ± 0.143
1.145CysAsn: 1.145 ± 0.186
1.403CysPro: 1.403 ± 0.23
0.916CysGln: 0.916 ± 0.153
1.26CysArg: 1.26 ± 0.207
1.689CysSer: 1.689 ± 0.235
1.317CysThr: 1.317 ± 0.145
1.632CysVal: 1.632 ± 0.218
0.286CysTrp: 0.286 ± 0.105
0.63CysTyr: 0.63 ± 0.132
0.0CysXaa: 0.0 ± 0.0
Asp
3.579AspAla: 3.579 ± 0.369
0.83AspCys: 0.83 ± 0.173
2.892AspAsp: 2.892 ± 0.426
2.778AspGlu: 2.778 ± 0.326
1.976AspPhe: 1.976 ± 0.243
3.322AspGly: 3.322 ± 0.315
1.031AspHis: 1.031 ± 0.185
3.121AspIle: 3.121 ± 0.326
1.775AspLys: 1.775 ± 0.207
4.553AspLeu: 4.553 ± 0.369
0.945AspMet: 0.945 ± 0.177
1.718AspAsn: 1.718 ± 0.23
3.35AspPro: 3.35 ± 0.327
1.432AspGln: 1.432 ± 0.226
2.864AspArg: 2.864 ± 0.306
3.436AspSer: 3.436 ± 0.315
3.15AspThr: 3.15 ± 0.276
3.78AspVal: 3.78 ± 0.349
0.573AspTrp: 0.573 ± 0.105
1.604AspTyr: 1.604 ± 0.216
0.0AspXaa: 0.0 ± 0.0
Glu
4.868GluAla: 4.868 ± 0.376
0.974GluCys: 0.974 ± 0.172
3.264GluAsp: 3.264 ± 0.406
3.923GluGlu: 3.923 ± 0.405
1.374GluPhe: 1.374 ± 0.162
2.606GluGly: 2.606 ± 0.311
1.775GluHis: 1.775 ± 0.214
3.035GluIle: 3.035 ± 0.322
2.234GluLys: 2.234 ± 0.201
5.04GluLeu: 5.04 ± 0.383
1.46GluMet: 1.46 ± 0.195
3.093GluAsn: 3.093 ± 0.376
3.035GluPro: 3.035 ± 0.302
2.205GluGln: 2.205 ± 0.337
2.405GluArg: 2.405 ± 0.233
4.066GluSer: 4.066 ± 0.338
4.181GluThr: 4.181 ± 0.384
3.15GluVal: 3.15 ± 0.322
0.544GluTrp: 0.544 ± 0.127
1.718GluTyr: 1.718 ± 0.225
0.0GluXaa: 0.0 ± 0.0
Phe
2.09PheAla: 2.09 ± 0.278
1.145PheCys: 1.145 ± 0.229
1.689PheAsp: 1.689 ± 0.19
1.861PheGlu: 1.861 ± 0.205
2.291PhePhe: 2.291 ± 0.241
2.148PheGly: 2.148 ± 0.261
1.06PheHis: 1.06 ± 0.171
2.978PheIle: 2.978 ± 0.297
1.747PheLys: 1.747 ± 0.261
5.04PheLeu: 5.04 ± 0.386
1.346PheMet: 1.346 ± 0.181
1.89PheAsn: 1.89 ± 0.247
2.291PhePro: 2.291 ± 0.27
1.46PheGln: 1.46 ± 0.19
2.062PheArg: 2.062 ± 0.245
3.522PheSer: 3.522 ± 0.338
3.007PheThr: 3.007 ± 0.361
2.864PheVal: 2.864 ± 0.246
0.515PheTrp: 0.515 ± 0.126
1.518PheTyr: 1.518 ± 0.2
0.0PheXaa: 0.0 ± 0.0
Gly
3.064GlyAla: 3.064 ± 0.259
0.974GlyCys: 0.974 ± 0.199
2.692GlyAsp: 2.692 ± 0.381
3.436GlyGlu: 3.436 ± 0.318
2.176GlyPhe: 2.176 ± 0.268
4.066GlyGly: 4.066 ± 0.509
1.775GlyHis: 1.775 ± 0.286
2.864GlyIle: 2.864 ± 0.35
2.491GlyLys: 2.491 ± 0.274
6.071GlyLeu: 6.071 ± 0.491
1.374GlyMet: 1.374 ± 0.181
2.52GlyAsn: 2.52 ± 0.211
3.379GlyPro: 3.379 ± 0.295
2.262GlyGln: 2.262 ± 0.248
3.808GlyArg: 3.808 ± 0.522
4.496GlySer: 4.496 ± 0.42
4.123GlyThr: 4.123 ± 0.41
4.238GlyVal: 4.238 ± 0.369
0.802GlyTrp: 0.802 ± 0.152
1.747GlyTyr: 1.747 ± 0.301
0.0GlyXaa: 0.0 ± 0.0
His
1.947HisAla: 1.947 ± 0.195
0.63HisCys: 0.63 ± 0.132
0.916HisAsp: 0.916 ± 0.127
1.289HisGlu: 1.289 ± 0.2
1.174HisPhe: 1.174 ± 0.193
2.062HisGly: 2.062 ± 0.215
1.031HisHis: 1.031 ± 0.155
1.718HisIle: 1.718 ± 0.261
1.174HisLys: 1.174 ± 0.221
3.35HisLeu: 3.35 ± 0.299
0.487HisMet: 0.487 ± 0.116
1.518HisAsn: 1.518 ± 0.233
2.291HisPro: 2.291 ± 0.384
0.83HisGln: 0.83 ± 0.147
1.46HisArg: 1.46 ± 0.25
1.689HisSer: 1.689 ± 0.227
2.004HisThr: 2.004 ± 0.21
1.775HisVal: 1.775 ± 0.211
0.258HisTrp: 0.258 ± 0.083
0.802HisTyr: 0.802 ± 0.131
0.0HisXaa: 0.0 ± 0.0
Ile
3.179IleAla: 3.179 ± 0.276
1.346IleCys: 1.346 ± 0.225
1.976IleAsp: 1.976 ± 0.259
2.549IleGlu: 2.549 ± 0.302
2.692IlePhe: 2.692 ± 0.295
2.405IleGly: 2.405 ± 0.258
1.403IleHis: 1.403 ± 0.242
3.522IleIle: 3.522 ± 0.317
2.52IleLys: 2.52 ± 0.3
5.813IleLeu: 5.813 ± 0.461
1.289IleMet: 1.289 ± 0.197
2.262IleAsn: 2.262 ± 0.292
4.038IlePro: 4.038 ± 0.384
2.434IleGln: 2.434 ± 0.266
3.179IleArg: 3.179 ± 0.25
4.524IleSer: 4.524 ± 0.335
4.066IleThr: 4.066 ± 0.405
3.007IleVal: 3.007 ± 0.272
0.63IleTrp: 0.63 ± 0.17
1.976IleTyr: 1.976 ± 0.289
0.0IleXaa: 0.0 ± 0.0
Lys
2.434LysAla: 2.434 ± 0.298
1.117LysCys: 1.117 ± 0.151
2.062LysAsp: 2.062 ± 0.23
2.634LysGlu: 2.634 ± 0.305
1.661LysPhe: 1.661 ± 0.235
1.775LysGly: 1.775 ± 0.204
1.145LysHis: 1.145 ± 0.175
2.634LysIle: 2.634 ± 0.262
1.89LysLys: 1.89 ± 0.297
3.78LysLeu: 3.78 ± 0.374
0.601LysMet: 0.601 ± 0.131
1.976LysAsn: 1.976 ± 0.266
2.663LysPro: 2.663 ± 0.311
1.689LysGln: 1.689 ± 0.222
2.806LysArg: 2.806 ± 0.303
3.637LysSer: 3.637 ± 0.342
3.408LysThr: 3.408 ± 0.3
2.234LysVal: 2.234 ± 0.289
0.229LysTrp: 0.229 ± 0.097
1.06LysTyr: 1.06 ± 0.151
0.0LysXaa: 0.0 ± 0.0
Leu
7.703LeuAla: 7.703 ± 0.533
2.864LeuCys: 2.864 ± 0.29
4.41LeuAsp: 4.41 ± 0.394
5.412LeuGlu: 5.412 ± 0.467
5.068LeuPhe: 5.068 ± 0.451
6.157LeuGly: 6.157 ± 0.549
2.835LeuHis: 2.835 ± 0.251
4.868LeuIle: 4.868 ± 0.406
4.553LeuLys: 4.553 ± 0.445
10.194LeuLeu: 10.194 ± 0.782
1.861LeuMet: 1.861 ± 0.262
3.952LeuAsn: 3.952 ± 0.269
5.613LeuPro: 5.613 ± 0.474
3.579LeuGln: 3.579 ± 0.319
6.357LeuArg: 6.357 ± 0.46
8.562LeuSer: 8.562 ± 0.463
7.13LeuThr: 7.13 ± 0.357
5.727LeuVal: 5.727 ± 0.469
1.117LeuTrp: 1.117 ± 0.173
3.15LeuTyr: 3.15 ± 0.378
0.0LeuXaa: 0.0 ± 0.0
Met
2.176MetAla: 2.176 ± 0.273
0.601MetCys: 0.601 ± 0.146
1.403MetAsp: 1.403 ± 0.172
1.546MetGlu: 1.546 ± 0.198
1.374MetPhe: 1.374 ± 0.186
1.174MetGly: 1.174 ± 0.193
0.487MetHis: 0.487 ± 0.107
1.031MetIle: 1.031 ± 0.141
0.601MetLys: 0.601 ± 0.123
2.004MetLeu: 2.004 ± 0.218
0.573MetMet: 0.573 ± 0.134
0.945MetAsn: 0.945 ± 0.17
1.031MetPro: 1.031 ± 0.207
0.573MetGln: 0.573 ± 0.12
1.031MetArg: 1.031 ± 0.159
1.718MetSer: 1.718 ± 0.219
1.46MetThr: 1.46 ± 0.195
1.632MetVal: 1.632 ± 0.253
0.372MetTrp: 0.372 ± 0.087
0.802MetTyr: 0.802 ± 0.133
0.0MetXaa: 0.0 ± 0.0
Asn
2.348AsnAla: 2.348 ± 0.225
0.802AsnCys: 0.802 ± 0.134
1.747AsnAsp: 1.747 ± 0.24
2.062AsnGlu: 2.062 ± 0.273
1.747AsnPhe: 1.747 ± 0.241
2.205AsnGly: 2.205 ± 0.259
1.117AsnHis: 1.117 ± 0.159
2.663AsnIle: 2.663 ± 0.311
2.434AsnLys: 2.434 ± 0.263
4.038AsnLeu: 4.038 ± 0.358
1.174AsnMet: 1.174 ± 0.17
1.976AsnAsn: 1.976 ± 0.22
3.15AsnPro: 3.15 ± 0.42
1.346AsnGln: 1.346 ± 0.199
2.434AsnArg: 2.434 ± 0.321
3.207AsnSer: 3.207 ± 0.306
2.606AsnThr: 2.606 ± 0.281
3.293AsnVal: 3.293 ± 0.314
0.43AsnTrp: 0.43 ± 0.112
1.26AsnTyr: 1.26 ± 0.198
0.0AsnXaa: 0.0 ± 0.0
Pro
3.408ProAla: 3.408 ± 0.293
1.604ProCys: 1.604 ± 0.2
3.035ProAsp: 3.035 ± 0.275
3.579ProGlu: 3.579 ± 0.353
2.033ProPhe: 2.033 ± 0.214
5.383ProGly: 5.383 ± 0.875
2.033ProHis: 2.033 ± 0.218
3.264ProIle: 3.264 ± 0.349
1.976ProLys: 1.976 ± 0.232
5.04ProLeu: 5.04 ± 0.329
0.945ProMet: 0.945 ± 0.178
2.491ProAsn: 2.491 ± 0.262
4.782ProPro: 4.782 ± 0.861
2.205ProGln: 2.205 ± 0.349
3.637ProArg: 3.637 ± 0.355
5.011ProSer: 5.011 ± 0.481
4.238ProThr: 4.238 ± 0.45
4.295ProVal: 4.295 ± 0.409
0.773ProTrp: 0.773 ± 0.144
1.632ProTyr: 1.632 ± 0.223
0.0ProXaa: 0.0 ± 0.0
Gln
2.634GlnAla: 2.634 ± 0.338
0.601GlnCys: 0.601 ± 0.119
1.833GlnAsp: 1.833 ± 0.209
2.033GlnGlu: 2.033 ± 0.256
1.804GlnPhe: 1.804 ± 0.248
1.919GlnGly: 1.919 ± 0.264
1.145GlnHis: 1.145 ± 0.176
1.804GlnIle: 1.804 ± 0.216
1.947GlnLys: 1.947 ± 0.224
2.377GlnLeu: 2.377 ± 0.273
0.745GlnMet: 0.745 ± 0.162
1.489GlnAsn: 1.489 ± 0.211
2.348GlnPro: 2.348 ± 0.364
1.718GlnGln: 1.718 ± 0.316
2.205GlnArg: 2.205 ± 0.224
2.634GlnSer: 2.634 ± 0.315
3.064GlnThr: 3.064 ± 0.257
1.89GlnVal: 1.89 ± 0.225
0.43GlnTrp: 0.43 ± 0.11
0.974GlnTyr: 0.974 ± 0.208
0.0GlnXaa: 0.0 ± 0.0
Arg
4.238ArgAla: 4.238 ± 0.331
1.546ArgCys: 1.546 ± 0.239
3.493ArgAsp: 3.493 ± 0.377
3.694ArgGlu: 3.694 ± 0.342
1.575ArgPhe: 1.575 ± 0.217
4.181ArgGly: 4.181 ± 0.574
1.947ArgHis: 1.947 ± 0.262
2.749ArgIle: 2.749 ± 0.256
2.577ArgLys: 2.577 ± 0.348
6.099ArgLeu: 6.099 ± 0.411
1.374ArgMet: 1.374 ± 0.202
2.234ArgAsn: 2.234 ± 0.243
3.293ArgPro: 3.293 ± 0.361
2.033ArgGln: 2.033 ± 0.282
4.467ArgArg: 4.467 ± 0.428
3.522ArgSer: 3.522 ± 0.265
2.72ArgThr: 2.72 ± 0.265
3.923ArgVal: 3.923 ± 0.343
0.716ArgTrp: 0.716 ± 0.187
2.004ArgTyr: 2.004 ± 0.26
0.0ArgXaa: 0.0 ± 0.0
Ser
5.154SerAla: 5.154 ± 0.365
1.775SerCys: 1.775 ± 0.248
3.98SerAsp: 3.98 ± 0.338
4.381SerGlu: 4.381 ± 0.441
3.293SerPhe: 3.293 ± 0.305
4.524SerGly: 4.524 ± 0.389
2.405SerHis: 2.405 ± 0.244
4.467SerIle: 4.467 ± 0.355
3.15SerLys: 3.15 ± 0.341
8.848SerLeu: 8.848 ± 0.547
1.947SerMet: 1.947 ± 0.197
2.778SerAsn: 2.778 ± 0.332
4.811SerPro: 4.811 ± 0.527
3.007SerGln: 3.007 ± 0.419
4.668SerArg: 4.668 ± 0.336
6.758SerSer: 6.758 ± 0.627
5.326SerThr: 5.326 ± 0.411
5.87SerVal: 5.87 ± 0.408
0.745SerTrp: 0.745 ± 0.18
1.804SerTyr: 1.804 ± 0.22
0.0SerXaa: 0.0 ± 0.0
Thr
4.868ThrAla: 4.868 ± 0.403
1.632ThrCys: 1.632 ± 0.258
3.522ThrAsp: 3.522 ± 0.325
3.35ThrGlu: 3.35 ± 0.299
3.207ThrPhe: 3.207 ± 0.356
3.923ThrGly: 3.923 ± 0.409
1.919ThrHis: 1.919 ± 0.27
3.15ThrIle: 3.15 ± 0.243
2.52ThrLys: 2.52 ± 0.241
7.875ThrLeu: 7.875 ± 0.508
1.374ThrMet: 1.374 ± 0.17
2.491ThrAsn: 2.491 ± 0.328
3.98ThrPro: 3.98 ± 0.446
2.52ThrGln: 2.52 ± 0.3
4.353ThrArg: 4.353 ± 0.65
5.842ThrSer: 5.842 ± 0.433
4.467ThrThr: 4.467 ± 0.405
4.954ThrVal: 4.954 ± 0.41
1.088ThrTrp: 1.088 ± 0.164
2.319ThrTyr: 2.319 ± 0.24
0.0ThrXaa: 0.0 ± 0.0
Val
4.209ValAla: 4.209 ± 0.324
2.148ValCys: 2.148 ± 0.328
3.436ValAsp: 3.436 ± 0.368
3.837ValGlu: 3.837 ± 0.353
3.15ValPhe: 3.15 ± 0.388
3.207ValGly: 3.207 ± 0.341
1.489ValHis: 1.489 ± 0.186
3.637ValIle: 3.637 ± 0.337
2.52ValLys: 2.52 ± 0.309
6.157ValLeu: 6.157 ± 0.375
1.747ValMet: 1.747 ± 0.192
2.778ValAsn: 2.778 ± 0.35
4.181ValPro: 4.181 ± 0.364
1.919ValGln: 1.919 ± 0.22
3.608ValArg: 3.608 ± 0.286
5.698ValSer: 5.698 ± 0.43
5.097ValThr: 5.097 ± 0.518
3.808ValVal: 3.808 ± 0.35
0.745ValTrp: 0.745 ± 0.137
2.491ValTyr: 2.491 ± 0.299
0.0ValXaa: 0.0 ± 0.0
Trp
0.859TrpAla: 0.859 ± 0.232
0.229TrpCys: 0.229 ± 0.072
0.601TrpAsp: 0.601 ± 0.147
0.601TrpGlu: 0.601 ± 0.125
0.315TrpPhe: 0.315 ± 0.09
0.659TrpGly: 0.659 ± 0.161
0.515TrpHis: 0.515 ± 0.144
0.601TrpIle: 0.601 ± 0.16
0.515TrpLys: 0.515 ± 0.118
1.546TrpLeu: 1.546 ± 0.19
0.286TrpMet: 0.286 ± 0.091
0.83TrpAsn: 0.83 ± 0.151
0.802TrpPro: 0.802 ± 0.134
0.229TrpGln: 0.229 ± 0.087
0.573TrpArg: 0.573 ± 0.133
0.888TrpSer: 0.888 ± 0.146
0.888TrpThr: 0.888 ± 0.188
0.601TrpVal: 0.601 ± 0.14
0.143TrpTrp: 0.143 ± 0.059
0.344TrpTyr: 0.344 ± 0.101
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.004TyrAla: 2.004 ± 0.203
0.802TyrCys: 0.802 ± 0.138
1.632TyrAsp: 1.632 ± 0.236
1.919TyrGlu: 1.919 ± 0.224
1.575TyrPhe: 1.575 ± 0.246
2.004TyrGly: 2.004 ± 0.212
0.773TyrHis: 0.773 ± 0.124
1.575TyrIle: 1.575 ± 0.21
1.46TyrLys: 1.46 ± 0.233
3.064TyrLeu: 3.064 ± 0.268
0.601TyrMet: 0.601 ± 0.127
1.604TyrAsn: 1.604 ± 0.214
1.489TyrPro: 1.489 ± 0.263
0.974TyrGln: 0.974 ± 0.175
1.317TyrArg: 1.317 ± 0.182
2.319TyrSer: 2.319 ± 0.297
2.176TyrThr: 2.176 ± 0.256
2.176TyrVal: 2.176 ± 0.318
0.315TyrTrp: 0.315 ± 0.093
1.002TyrTyr: 1.002 ± 0.201
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 72 proteins (34923 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski