Amino acid dipepetide frequency for Fulvimonas soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	23.05AlaAla: 23.05 ± 0.223	1.385AlaCys: 1.385 ± 0.038	7.574AlaAsp: 7.574 ± 0.099	7.332AlaGlu: 7.332 ± 0.102	4.146AlaPhe: 4.146 ± 0.059	13.424AlaGly: 13.424 ± 0.165	2.967AlaHis: 2.967 ± 0.058	4.886AlaIle: 4.886 ± 0.077	3.071AlaLys: 3.071 ± 0.072	18.047AlaLeu: 18.047 ± 0.2	3.354AlaMet: 3.354 ± 0.057	2.604AlaAsn: 2.604 ± 0.05	7.94AlaPro: 7.94 ± 0.103	5.627AlaGln: 5.627 ± 0.097	12.03AlaArg: 12.03 ± 0.147	6.033AlaSer: 6.033 ± 0.09	5.778AlaThr: 5.778 ± 0.087	9.547AlaVal: 9.547 ± 0.108	2.389AlaTrp: 2.389 ± 0.05	2.729AlaTyr: 2.729 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	1.183CysAla: 1.183 ± 0.034	0.11CysCys: 0.11 ± 0.01	0.45CysAsp: 0.45 ± 0.024	0.434CysGlu: 0.434 ± 0.019	0.275CysPhe: 0.275 ± 0.015	0.96CysGly: 0.96 ± 0.029	0.246CysHis: 0.246 ± 0.017	0.28CysIle: 0.28 ± 0.017	0.171CysLys: 0.171 ± 0.014	0.885CysLeu: 0.885 ± 0.029	0.131CysMet: 0.131 ± 0.011	0.205CysAsn: 0.205 ± 0.014	0.43CysPro: 0.43 ± 0.021	0.194CysGln: 0.194 ± 0.012	0.623CysArg: 0.623 ± 0.025	0.371CysSer: 0.371 ± 0.018	0.371CysThr: 0.371 ± 0.022	0.597CysVal: 0.597 ± 0.024	0.117CysTrp: 0.117 ± 0.01	0.218CysTyr: 0.218 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	8.683AspAla: 8.683 ± 0.111	0.434AspCys: 0.434 ± 0.024	3.197AspAsp: 3.197 ± 0.064	3.239AspGlu: 3.239 ± 0.06	2.075AspPhe: 2.075 ± 0.049	6.17AspGly: 6.17 ± 0.101	1.165AspHis: 1.165 ± 0.032	1.951AspIle: 1.951 ± 0.042	1.393AspLys: 1.393 ± 0.041	5.459AspLeu: 5.459 ± 0.071	0.966AspMet: 0.966 ± 0.031	1.195AspAsn: 1.195 ± 0.038	3.681AspPro: 3.681 ± 0.064	1.516AspGln: 1.516 ± 0.039	3.896AspArg: 3.896 ± 0.061	2.116AspSer: 2.116 ± 0.048	2.398AspThr: 2.398 ± 0.055	3.953AspVal: 3.953 ± 0.055	1.146AspTrp: 1.146 ± 0.035	1.736AspTyr: 1.736 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	7.325GluAla: 7.325 ± 0.097	0.325GluCys: 0.325 ± 0.018	2.25GluAsp: 2.25 ± 0.058	2.488GluGlu: 2.488 ± 0.069	1.484GluPhe: 1.484 ± 0.043	3.851GluGly: 3.851 ± 0.065	1.444GluHis: 1.444 ± 0.033	2.096GluIle: 2.096 ± 0.052	1.424GluLys: 1.424 ± 0.047	6.439GluLeu: 6.439 ± 0.095	0.866GluMet: 0.866 ± 0.03	1.057GluAsn: 1.057 ± 0.034	2.735GluPro: 2.735 ± 0.058	2.423GluGln: 2.423 ± 0.045	5.514GluArg: 5.514 ± 0.085	2.092GluSer: 2.092 ± 0.046	2.233GluThr: 2.233 ± 0.039	3.693GluVal: 3.693 ± 0.065	0.649GluTrp: 0.649 ± 0.024	1.069GluTyr: 1.069 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.525PheAla: 4.525 ± 0.07	0.29PheCys: 0.29 ± 0.014	2.428PheAsp: 2.428 ± 0.047	1.738PheGlu: 1.738 ± 0.039	1.128PhePhe: 1.128 ± 0.039	3.469PheGly: 3.469 ± 0.061	0.755PheHis: 0.755 ± 0.026	0.978PheIle: 0.978 ± 0.033	0.785PheLys: 0.785 ± 0.026	3.027PheLeu: 3.027 ± 0.061	0.585PheMet: 0.585 ± 0.025	0.935PheAsn: 0.935 ± 0.031	1.442PhePro: 1.442 ± 0.039	0.928PheGln: 0.928 ± 0.029	2.332PheArg: 2.332 ± 0.047	1.619PheSer: 1.619 ± 0.039	1.517PheThr: 1.517 ± 0.048	2.624PheVal: 2.624 ± 0.053	0.459PheTrp: 0.459 ± 0.025	0.847PheTyr: 0.847 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	11.173GlyAla: 11.173 ± 0.136	0.859GlyCys: 0.859 ± 0.03	4.863GlyAsp: 4.863 ± 0.069	5.073GlyGlu: 5.073 ± 0.088	3.309GlyPhe: 3.309 ± 0.051	8.433GlyGly: 8.433 ± 0.159	2.266GlyHis: 2.266 ± 0.05	3.592GlyIle: 3.592 ± 0.052	2.838GlyLys: 2.838 ± 0.061	9.301GlyLeu: 9.301 ± 0.11	2.31GlyMet: 2.31 ± 0.043	2.201GlyAsn: 2.201 ± 0.055	3.351GlyPro: 3.351 ± 0.058	3.157GlyGln: 3.157 ± 0.063	7.367GlyArg: 7.367 ± 0.095	4.702GlySer: 4.702 ± 0.099	4.446GlyThr: 4.446 ± 0.117	6.669GlyVal: 6.669 ± 0.078	1.766GlyTrp: 1.766 ± 0.048	2.724GlyTyr: 2.724 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	3.513HisAla: 3.513 ± 0.055	0.242HisCys: 0.242 ± 0.014	1.309HisAsp: 1.309 ± 0.036	1.197HisGlu: 1.197 ± 0.033	0.846HisPhe: 0.846 ± 0.028	2.62HisGly: 2.62 ± 0.05	0.591HisHis: 0.591 ± 0.026	0.665HisIle: 0.665 ± 0.027	0.422HisLys: 0.422 ± 0.021	2.222HisLeu: 2.222 ± 0.049	0.467HisMet: 0.467 ± 0.023	0.435HisAsn: 0.435 ± 0.022	1.65HisPro: 1.65 ± 0.037	0.567HisGln: 0.567 ± 0.022	1.734HisArg: 1.734 ± 0.043	0.86HisSer: 0.86 ± 0.026	0.903HisThr: 0.903 ± 0.028	1.698HisVal: 1.698 ± 0.041	0.431HisTrp: 0.431 ± 0.021	0.705HisTyr: 0.705 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.402IleAla: 5.402 ± 0.083	0.263IleCys: 0.263 ± 0.016	2.757IleAsp: 2.757 ± 0.053	2.496IleGlu: 2.496 ± 0.052	0.945IlePhe: 0.945 ± 0.032	3.708IleGly: 3.708 ± 0.063	0.713IleHis: 0.713 ± 0.026	0.982IleIle: 0.982 ± 0.037	0.899IleLys: 0.899 ± 0.03	2.706IleLeu: 2.706 ± 0.058	0.408IleMet: 0.408 ± 0.022	1.004IleAsn: 1.004 ± 0.032	1.793IlePro: 1.793 ± 0.047	0.94IleGln: 0.94 ± 0.029	2.549IleArg: 2.549 ± 0.055	1.579IleSer: 1.579 ± 0.043	1.712IleThr: 1.712 ± 0.048	2.961IleVal: 2.961 ± 0.048	0.344IleTrp: 0.344 ± 0.021	0.796IleTyr: 0.796 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	3.311LysAla: 3.311 ± 0.078	0.115LysCys: 0.115 ± 0.01	1.353LysAsp: 1.353 ± 0.045	1.104LysGlu: 1.104 ± 0.044	0.633LysPhe: 0.633 ± 0.027	1.919LysGly: 1.919 ± 0.049	0.505LysHis: 0.505 ± 0.02	0.921LysIle: 0.921 ± 0.032	0.911LysLys: 0.911 ± 0.046	2.89LysLeu: 2.89 ± 0.057	0.481LysMet: 0.481 ± 0.021	0.624LysAsn: 0.624 ± 0.031	1.77LysPro: 1.77 ± 0.046	1.01LysGln: 1.01 ± 0.035	1.869LysArg: 1.869 ± 0.046	1.152LysSer: 1.152 ± 0.04	1.231LysThr: 1.231 ± 0.034	1.966LysVal: 1.966 ± 0.053	0.259LysTrp: 0.259 ± 0.017	0.578LysTyr: 0.578 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	18.555LeuAla: 18.555 ± 0.215	1.033LeuCys: 1.033 ± 0.032	7.248LeuAsp: 7.248 ± 0.097	5.397LeuGlu: 5.397 ± 0.072	3.408LeuPhe: 3.408 ± 0.059	9.855LeuGly: 9.855 ± 0.103	2.503LeuHis: 2.503 ± 0.049	3.152LeuIle: 3.152 ± 0.06	3.033LeuLys: 3.033 ± 0.059	13.262LeuLeu: 13.262 ± 0.178	1.84LeuMet: 1.84 ± 0.042	2.217LeuAsn: 2.217 ± 0.045	7.216LeuPro: 7.216 ± 0.084	3.375LeuGln: 3.375 ± 0.062	9.769LeuArg: 9.769 ± 0.13	5.255LeuSer: 5.255 ± 0.08	4.595LeuThr: 4.595 ± 0.079	7.787LeuVal: 7.787 ± 0.085	1.52LeuTrp: 1.52 ± 0.041	2.416LeuTyr: 2.416 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.526MetAla: 2.526 ± 0.048	0.112MetCys: 0.112 ± 0.01	1.02MetAsp: 1.02 ± 0.028	0.826MetGlu: 0.826 ± 0.03	0.551MetPhe: 0.551 ± 0.025	1.366MetGly: 1.366 ± 0.033	0.469MetHis: 0.469 ± 0.023	0.699MetIle: 0.699 ± 0.024	0.692MetLys: 0.692 ± 0.026	2.343MetLeu: 2.343 ± 0.052	0.331MetMet: 0.331 ± 0.02	0.62MetAsn: 0.62 ± 0.024	1.328MetPro: 1.328 ± 0.039	0.806MetGln: 0.806 ± 0.027	1.809MetArg: 1.809 ± 0.048	1.338MetSer: 1.338 ± 0.034	1.064MetThr: 1.064 ± 0.029	1.264MetVal: 1.264 ± 0.037	0.178MetTrp: 0.178 ± 0.013	0.347MetTyr: 0.347 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.071AsnAla: 3.071 ± 0.054	0.163AsnCys: 0.163 ± 0.013	1.261AsnAsp: 1.261 ± 0.035	0.987AsnGlu: 0.987 ± 0.032	0.766AsnPhe: 0.766 ± 0.032	2.267AsnGly: 2.267 ± 0.055	0.486AsnHis: 0.486 ± 0.02	0.855AsnIle: 0.855 ± 0.033	0.496AsnLys: 0.496 ± 0.025	2.425AsnLeu: 2.425 ± 0.05	0.36AsnMet: 0.36 ± 0.018	0.608AsnAsn: 0.608 ± 0.026	1.535AsnPro: 1.535 ± 0.038	0.74AsnGln: 0.74 ± 0.03	1.606AsnArg: 1.606 ± 0.045	0.904AsnSer: 0.904 ± 0.031	1.086AsnThr: 1.086 ± 0.038	1.727AsnVal: 1.727 ± 0.04	0.351AsnTrp: 0.351 ± 0.021	0.726AsnTyr: 0.726 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	9.404ProAla: 9.404 ± 0.135	0.384ProCys: 0.384 ± 0.021	3.493ProAsp: 3.493 ± 0.059	3.172ProGlu: 3.172 ± 0.057	1.79ProPhe: 1.79 ± 0.045	5.352ProGly: 5.352 ± 0.079	1.315ProHis: 1.315 ± 0.033	1.585ProIle: 1.585 ± 0.04	1.216ProLys: 1.216 ± 0.035	6.056ProLeu: 6.056 ± 0.074	1.219ProMet: 1.219 ± 0.032	1.134ProAsn: 1.134 ± 0.033	3.829ProPro: 3.829 ± 0.095	2.096ProGln: 2.096 ± 0.047	4.216ProArg: 4.216 ± 0.062	2.64ProSer: 2.64 ± 0.055	2.108ProThr: 2.108 ± 0.051	4.257ProVal: 4.257 ± 0.061	0.949ProTrp: 0.949 ± 0.028	1.321ProTyr: 1.321 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	5.419GlnAla: 5.419 ± 0.086	0.21GlnCys: 0.21 ± 0.015	1.594GlnAsp: 1.594 ± 0.04	1.343GlnGlu: 1.343 ± 0.039	1.042GlnPhe: 1.042 ± 0.031	2.868GlnGly: 2.868 ± 0.043	0.78GlnHis: 0.78 ± 0.026	1.27GlnIle: 1.27 ± 0.037	0.786GlnLys: 0.786 ± 0.028	4.006GlnLeu: 4.006 ± 0.07	0.661GlnMet: 0.661 ± 0.025	0.704GlnAsn: 0.704 ± 0.029	2.249GlnPro: 2.249 ± 0.049	1.713GlnGln: 1.713 ± 0.053	3.387GlnArg: 3.387 ± 0.066	1.549GlnSer: 1.549 ± 0.041	1.449GlnThr: 1.449 ± 0.039	2.78GlnVal: 2.78 ± 0.052	0.552GlnTrp: 0.552 ± 0.022	0.824GlnTyr: 0.824 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	10.545ArgAla: 10.545 ± 0.125	0.637ArgCys: 0.637 ± 0.023	4.244ArgAsp: 4.244 ± 0.066	5.036ArgGlu: 5.036 ± 0.086	2.952ArgPhe: 2.952 ± 0.062	6.255ArgGly: 6.255 ± 0.084	2.314ArgHis: 2.314 ± 0.053	3.568ArgIle: 3.568 ± 0.062	1.918ArgLys: 1.918 ± 0.045	10.137ArgLeu: 10.137 ± 0.127	1.905ArgMet: 1.905 ± 0.042	1.718ArgAsn: 1.718 ± 0.037	4.443ArgPro: 4.443 ± 0.075	3.15ArgGln: 3.15 ± 0.064	8.004ArgArg: 8.004 ± 0.115	3.378ArgSer: 3.378 ± 0.056	3.241ArgThr: 3.241 ± 0.062	5.527ArgVal: 5.527 ± 0.087	1.532ArgTrp: 1.532 ± 0.042	2.399ArgTyr: 2.399 ± 0.054	0.0ArgXaa: 0.0 ± 0.0
Ser	5.807SerAla: 5.807 ± 0.082	0.359SerCys: 0.359 ± 0.019	2.327SerAsp: 2.327 ± 0.052	1.945SerGlu: 1.945 ± 0.043	1.827SerPhe: 1.827 ± 0.042	4.746SerGly: 4.746 ± 0.105	1.042SerHis: 1.042 ± 0.032	1.804SerIle: 1.804 ± 0.047	1.047SerLys: 1.047 ± 0.038	4.899SerLeu: 4.899 ± 0.084	0.983SerMet: 0.983 ± 0.028	1.128SerAsn: 1.128 ± 0.037	2.68SerPro: 2.68 ± 0.055	1.486SerGln: 1.486 ± 0.046	3.349SerArg: 3.349 ± 0.066	2.461SerSer: 2.461 ± 0.061	2.352SerThr: 2.352 ± 0.05	3.321SerVal: 3.321 ± 0.052	0.687SerTrp: 0.687 ± 0.028	1.388SerTyr: 1.388 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	5.618ThrAla: 5.618 ± 0.092	0.327ThrCys: 0.327 ± 0.019	2.297ThrAsp: 2.297 ± 0.052	1.793ThrGlu: 1.793 ± 0.042	1.392ThrPhe: 1.392 ± 0.044	4.204ThrGly: 4.204 ± 0.088	0.975ThrHis: 0.975 ± 0.031	1.656ThrIle: 1.656 ± 0.052	0.785ThrLys: 0.785 ± 0.032	5.845ThrLeu: 5.845 ± 0.101	0.796ThrMet: 0.796 ± 0.027	0.95ThrAsn: 0.95 ± 0.032	3.203ThrPro: 3.203 ± 0.059	1.409ThrGln: 1.409 ± 0.048	3.257ThrArg: 3.257 ± 0.061	2.035ThrSer: 2.035 ± 0.051	2.209ThrThr: 2.209 ± 0.077	3.948ThrVal: 3.948 ± 0.084	0.597ThrTrp: 0.597 ± 0.024	1.154ThrTyr: 1.154 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	9.998ValAla: 9.998 ± 0.1	0.627ValCys: 0.627 ± 0.023	4.433ValAsp: 4.433 ± 0.063	4.194ValGlu: 4.194 ± 0.073	2.377ValPhe: 2.377 ± 0.047	5.607ValGly: 5.607 ± 0.083	1.612ValHis: 1.612 ± 0.04	2.704ValIle: 2.704 ± 0.051	1.784ValLys: 1.784 ± 0.049	8.332ValLeu: 8.332 ± 0.09	1.337ValMet: 1.337 ± 0.037	1.95ValAsn: 1.95 ± 0.049	4.139ValPro: 4.139 ± 0.063	2.427ValGln: 2.427 ± 0.054	5.658ValArg: 5.658 ± 0.083	3.633ValSer: 3.633 ± 0.065	3.695ValThr: 3.695 ± 0.083	5.8ValVal: 5.8 ± 0.084	0.898ValTrp: 0.898 ± 0.033	1.694ValTyr: 1.694 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.363TrpAla: 1.363 ± 0.037	0.165TrpCys: 0.165 ± 0.013	0.7TrpAsp: 0.7 ± 0.027	0.512TrpGlu: 0.512 ± 0.022	0.552TrpPhe: 0.552 ± 0.023	0.971TrpGly: 0.971 ± 0.035	0.436TrpHis: 0.436 ± 0.021	0.648TrpIle: 0.648 ± 0.024	0.4TrpLys: 0.4 ± 0.018	2.444TrpLeu: 2.444 ± 0.058	0.342TrpMet: 0.342 ± 0.018	0.495TrpAsn: 0.495 ± 0.019	0.883TrpPro: 0.883 ± 0.028	0.741TrpGln: 0.741 ± 0.025	1.606TrpArg: 1.606 ± 0.045	0.846TrpSer: 0.846 ± 0.028	0.824TrpThr: 0.824 ± 0.028	0.912TrpVal: 0.912 ± 0.028	0.3TrpTrp: 0.3 ± 0.02	0.395TrpTyr: 0.395 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.441TyrAla: 3.441 ± 0.062	0.209TyrCys: 0.209 ± 0.013	1.573TyrAsp: 1.573 ± 0.05	1.148TyrGlu: 1.148 ± 0.032	0.914TyrPhe: 0.914 ± 0.029	2.356TyrGly: 2.356 ± 0.058	0.496TyrHis: 0.496 ± 0.021	0.665TyrIle: 0.665 ± 0.026	0.532TyrLys: 0.532 ± 0.023	2.712TyrLeu: 2.712 ± 0.055	0.344TyrMet: 0.344 ± 0.019	0.637TyrAsn: 0.637 ± 0.028	1.24TyrPro: 1.24 ± 0.033	0.879TyrGln: 0.879 ± 0.031	2.329TyrArg: 2.329 ± 0.053	1.075TyrSer: 1.075 ± 0.041	1.236TyrThr: 1.236 ± 0.044	1.87TyrVal: 1.87 ± 0.047	0.409TyrTrp: 0.409 ± 0.023	0.799TyrTyr: 0.799 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3277 proteins (1098678 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---