Yersinia pestis

Taxonomy:

Average proteome isoelectric point is 6.54

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3910 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2U2H2B3|A0A2U2H2B3_YERPE Uncharacterized protein OS=Yersinia pestis OX=632 GN=YPO3245 PE=4 SV=1
MM1 pKa = 7.65KK2 pKa = 10.05ILVRR6 pKa = 11.84ISSSTDD12 pKa = 2.97YY13 pKa = 11.21DD14 pKa = 3.98VYY16 pKa = 10.97PLFMVKK22 pKa = 10.04CDD24 pKa = 3.57GLNDD28 pKa = 3.81EE29 pKa = 5.49EE30 pKa = 4.03IQAAIEE36 pKa = 4.17RR37 pKa = 11.84NLVEE41 pKa = 4.25YY42 pKa = 10.15TGMDD46 pKa = 3.74ADD48 pKa = 4.3SVHH51 pKa = 7.24VDD53 pKa = 3.62DD54 pKa = 7.1DD55 pKa = 4.74GVCWSNGSCWYY66 pKa = 10.82VDD68 pKa = 3.2DD69 pKa = 4.13TTPVSDD75 pKa = 3.86EE76 pKa = 4.25DD77 pKa = 3.77AAHH80 pKa = 7.27LEE82 pKa = 4.4RR83 pKa = 11.84ILGISTFEE91 pKa = 3.84

Molecular weight: 10.2 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q8ZBA7|RL27_YERPE 50S ribosomal protein L27 OS=Yersinia pestis OX=632 GN=rpmA PE=3 SV=1
MM1 pKa = 7.45KK2 pKa = 9.51RR3 pKa = 11.84TFQPSVLKK11 pKa = 10.6RR12 pKa = 11.84NRR14 pKa = 11.84SHH16 pKa = 7.16GFRR19 pKa = 11.84ARR21 pKa = 11.84MATKK25 pKa = 10.4NGRR28 pKa = 11.84QVLARR33 pKa = 11.84RR34 pKa = 11.84RR35 pKa = 11.84AKK37 pKa = 10.18SRR39 pKa = 11.84SRR41 pKa = 11.84LTVSKK46 pKa = 11.03

Molecular weight: 5.43 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3908

2

3910

1243634

14

3705

318.1

35.19

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.245 ± 0.049

1.038 ± 0.014

5.166 ± 0.033

5.493 ± 0.04

3.798 ± 0.03

7.261 ± 0.046

2.256 ± 0.024

6.229 ± 0.035

4.348 ± 0.039

10.933 ± 0.055

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.652 ± 0.021

4.095 ± 0.042

4.375 ± 0.032

4.846 ± 0.037

5.343 ± 0.036

6.297 ± 0.037

5.42 ± 0.045

6.899 ± 0.037

1.357 ± 0.018

2.949 ± 0.025
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski