Amino acid dipepetide frequency for Zambian malbrouck virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.907AlaAla: 9.907 ± 1.256
3.62AlaCys: 3.62 ± 0.721
3.81AlaAsp: 3.81 ± 1.056
3.429AlaGlu: 3.429 ± 1.181
5.334AlaPhe: 5.334 ± 1.512
4.953AlaGly: 4.953 ± 0.999
2.096AlaHis: 2.096 ± 0.683
7.239AlaIle: 7.239 ± 1.465
2.667AlaLys: 2.667 ± 0.679
10.859AlaLeu: 10.859 ± 1.208
0.762AlaMet: 0.762 ± 0.247
2.667AlaAsn: 2.667 ± 0.678
5.906AlaPro: 5.906 ± 1.49
2.858AlaGln: 2.858 ± 0.822
4.763AlaArg: 4.763 ± 0.955
5.144AlaSer: 5.144 ± 1.184
4.191AlaThr: 4.191 ± 1.027
4.763AlaVal: 4.763 ± 0.843
0.572AlaTrp: 0.572 ± 0.292
2.477AlaTyr: 2.477 ± 0.974
0.0AlaXaa: 0.0 ± 0.0
Cys
2.286CysAla: 2.286 ± 0.547
1.334CysCys: 1.334 ± 0.686
2.096CysAsp: 2.096 ± 0.506
1.143CysGlu: 1.143 ± 0.466
1.524CysPhe: 1.524 ± 0.708
2.096CysGly: 2.096 ± 0.67
2.096CysHis: 2.096 ± 0.946
1.715CysIle: 1.715 ± 0.674
1.143CysLys: 1.143 ± 0.343
2.858CysLeu: 2.858 ± 0.704
1.143CysMet: 1.143 ± 0.639
0.953CysAsn: 0.953 ± 0.357
1.143CysPro: 1.143 ± 0.618
0.762CysGln: 0.762 ± 0.286
1.524CysArg: 1.524 ± 0.52
2.858CysSer: 2.858 ± 0.726
2.667CysThr: 2.667 ± 0.755
2.858CysVal: 2.858 ± 0.985
0.953CysTrp: 0.953 ± 0.543
0.953CysTyr: 0.953 ± 0.63
0.0CysXaa: 0.0 ± 0.0
Asp
4.001AspAla: 4.001 ± 0.845
1.524AspCys: 1.524 ± 0.655
2.477AspAsp: 2.477 ± 0.605
0.762AspGlu: 0.762 ± 0.251
3.81AspPhe: 3.81 ± 0.934
3.62AspGly: 3.62 ± 1.081
0.762AspHis: 0.762 ± 0.292
2.286AspIle: 2.286 ± 0.783
1.524AspLys: 1.524 ± 0.561
5.144AspLeu: 5.144 ± 0.837
0.762AspMet: 0.762 ± 0.292
0.381AspAsn: 0.381 ± 0.265
4.572AspPro: 4.572 ± 1.066
0.953AspGln: 0.953 ± 0.351
1.905AspArg: 1.905 ± 0.626
1.905AspSer: 1.905 ± 0.626
2.858AspThr: 2.858 ± 0.441
3.62AspVal: 3.62 ± 1.021
1.143AspTrp: 1.143 ± 0.561
1.143AspTyr: 1.143 ± 0.586
0.0AspXaa: 0.0 ± 0.0
Glu
3.239GluAla: 3.239 ± 0.693
0.953GluCys: 0.953 ± 0.572
1.143GluAsp: 1.143 ± 0.322
0.762GluGlu: 0.762 ± 0.219
0.572GluPhe: 0.572 ± 0.399
2.667GluGly: 2.667 ± 1.043
1.334GluHis: 1.334 ± 0.699
1.905GluIle: 1.905 ± 0.41
1.334GluLys: 1.334 ± 0.53
3.62GluLeu: 3.62 ± 1.419
0.381GluMet: 0.381 ± 0.265
1.334GluAsn: 1.334 ± 0.306
2.477GluPro: 2.477 ± 0.808
0.953GluGln: 0.953 ± 0.429
1.905GluArg: 1.905 ± 0.39
2.858GluSer: 2.858 ± 0.92
1.905GluThr: 1.905 ± 0.545
2.286GluVal: 2.286 ± 0.815
0.953GluTrp: 0.953 ± 0.392
0.572GluTyr: 0.572 ± 0.439
0.0GluXaa: 0.0 ± 0.0
Phe
4.001PheAla: 4.001 ± 1.006
1.715PheCys: 1.715 ± 0.832
3.239PheAsp: 3.239 ± 0.732
1.334PheGlu: 1.334 ± 0.53
2.667PhePhe: 2.667 ± 0.542
3.048PheGly: 3.048 ± 1.131
0.953PheHis: 0.953 ± 0.347
3.429PheIle: 3.429 ± 0.723
2.286PheLys: 2.286 ± 0.456
3.81PheLeu: 3.81 ± 1.297
0.572PheMet: 0.572 ± 0.348
1.524PheAsn: 1.524 ± 1.134
2.286PhePro: 2.286 ± 0.617
1.715PheGln: 1.715 ± 0.97
1.905PheArg: 1.905 ± 0.351
5.525PheSer: 5.525 ± 1.858
3.62PheThr: 3.62 ± 1.688
3.81PheVal: 3.81 ± 1.296
0.191PheTrp: 0.191 ± 0.234
1.143PheTyr: 1.143 ± 0.67
0.0PheXaa: 0.0 ± 0.0
Gly
4.763GlyAla: 4.763 ± 1.49
2.477GlyCys: 2.477 ± 0.632
4.763GlyAsp: 4.763 ± 1.441
1.524GlyGlu: 1.524 ± 0.592
3.239GlyPhe: 3.239 ± 0.453
3.62GlyGly: 3.62 ± 0.771
2.477GlyHis: 2.477 ± 0.59
4.382GlyIle: 4.382 ± 0.583
3.429GlyLys: 3.429 ± 0.764
5.144GlyLeu: 5.144 ± 0.679
1.524GlyMet: 1.524 ± 0.524
2.096GlyAsn: 2.096 ± 0.535
2.858GlyPro: 2.858 ± 0.825
2.096GlyGln: 2.096 ± 0.448
3.62GlyArg: 3.62 ± 0.721
4.953GlySer: 4.953 ± 1.616
5.525GlyThr: 5.525 ± 1.148
4.382GlyVal: 4.382 ± 0.968
0.762GlyTrp: 0.762 ± 0.409
3.048GlyTyr: 3.048 ± 0.737
0.0GlyXaa: 0.0 ± 0.0
His
2.667HisAla: 2.667 ± 0.881
0.953HisCys: 0.953 ± 0.354
1.143HisAsp: 1.143 ± 0.703
0.762HisGlu: 0.762 ± 0.667
2.286HisPhe: 2.286 ± 0.949
2.286HisGly: 2.286 ± 0.632
1.143HisHis: 1.143 ± 0.529
2.096HisIle: 2.096 ± 0.88
0.762HisLys: 0.762 ± 0.292
2.858HisLeu: 2.858 ± 0.822
1.524HisMet: 1.524 ± 0.37
1.715HisAsn: 1.715 ± 0.738
1.905HisPro: 1.905 ± 0.771
1.143HisGln: 1.143 ± 0.717
0.953HisArg: 0.953 ± 0.884
1.715HisSer: 1.715 ± 1.349
2.096HisThr: 2.096 ± 0.789
1.524HisVal: 1.524 ± 0.363
0.762HisTrp: 0.762 ± 0.307
1.143HisTyr: 1.143 ± 0.341
0.0HisXaa: 0.0 ± 0.0
Ile
3.81IleAla: 3.81 ± 0.815
2.477IleCys: 2.477 ± 0.771
1.905IleAsp: 1.905 ± 0.845
1.334IleGlu: 1.334 ± 0.371
2.858IlePhe: 2.858 ± 1.523
3.429IleGly: 3.429 ± 0.702
0.762IleHis: 0.762 ± 0.523
3.239IleIle: 3.239 ± 0.837
2.667IleLys: 2.667 ± 0.803
5.906IleLeu: 5.906 ± 1.445
0.762IleMet: 0.762 ± 0.33
1.334IleAsn: 1.334 ± 0.477
3.429IlePro: 3.429 ± 1.24
2.096IleGln: 2.096 ± 0.747
1.524IleArg: 1.524 ± 0.687
4.001IleSer: 4.001 ± 1.088
6.287IleThr: 6.287 ± 1.29
4.001IleVal: 4.001 ± 0.63
0.0IleTrp: 0.0 ± 0.0
1.334IleTyr: 1.334 ± 0.681
0.0IleXaa: 0.0 ± 0.0
Lys
2.858LysAla: 2.858 ± 0.613
1.524LysCys: 1.524 ± 0.794
1.334LysAsp: 1.334 ± 0.57
0.953LysGlu: 0.953 ± 0.854
3.048LysPhe: 3.048 ± 0.804
2.096LysGly: 2.096 ± 0.485
1.334LysHis: 1.334 ± 0.488
1.524LysIle: 1.524 ± 0.527
2.667LysLys: 2.667 ± 0.825
5.906LysLeu: 5.906 ± 1.385
0.953LysMet: 0.953 ± 0.66
1.715LysAsn: 1.715 ± 0.628
2.667LysPro: 2.667 ± 0.692
1.715LysGln: 1.715 ± 0.59
1.715LysArg: 1.715 ± 0.483
2.096LysSer: 2.096 ± 0.421
3.048LysThr: 3.048 ± 0.725
3.048LysVal: 3.048 ± 0.82
0.191LysTrp: 0.191 ± 0.174
0.953LysTyr: 0.953 ± 0.344
0.0LysXaa: 0.0 ± 0.0
Leu
10.478LeuAla: 10.478 ± 2.279
3.62LeuCys: 3.62 ± 0.799
5.334LeuAsp: 5.334 ± 1.171
3.81LeuGlu: 3.81 ± 0.793
4.953LeuPhe: 4.953 ± 1.015
6.096LeuGly: 6.096 ± 0.577
2.667LeuHis: 2.667 ± 1.026
5.715LeuIle: 5.715 ± 1.373
4.191LeuLys: 4.191 ± 0.658
11.812LeuLeu: 11.812 ± 3.353
1.524LeuMet: 1.524 ± 0.525
3.81LeuAsn: 3.81 ± 0.782
6.287LeuPro: 6.287 ± 1.199
2.667LeuGln: 2.667 ± 1.192
5.715LeuArg: 5.715 ± 1.459
7.239LeuSer: 7.239 ± 1.103
6.668LeuThr: 6.668 ± 1.579
7.43LeuVal: 7.43 ± 1.053
1.524LeuTrp: 1.524 ± 0.564
2.286LeuTyr: 2.286 ± 0.517
0.0LeuXaa: 0.0 ± 0.0
Met
2.286MetAla: 2.286 ± 0.45
0.572MetCys: 0.572 ± 0.293
0.381MetAsp: 0.381 ± 0.27
0.381MetGlu: 0.381 ± 0.281
0.191MetPhe: 0.191 ± 0.258
1.715MetGly: 1.715 ± 0.443
0.381MetHis: 0.381 ± 0.272
1.334MetIle: 1.334 ± 0.391
0.762MetLys: 0.762 ± 0.365
0.953MetLeu: 0.953 ± 0.472
0.191MetMet: 0.191 ± 0.174
0.572MetAsn: 0.572 ± 0.218
1.334MetPro: 1.334 ± 0.327
0.191MetGln: 0.191 ± 0.133
0.953MetArg: 0.953 ± 0.544
0.572MetSer: 0.572 ± 0.218
0.572MetThr: 0.572 ± 0.398
1.715MetVal: 1.715 ± 0.564
0.191MetTrp: 0.191 ± 0.133
0.572MetTyr: 0.572 ± 0.218
0.0MetXaa: 0.0 ± 0.0
Asn
1.905AsnAla: 1.905 ± 0.727
1.524AsnCys: 1.524 ± 0.409
1.334AsnAsp: 1.334 ± 0.57
2.667AsnGlu: 2.667 ± 0.809
2.096AsnPhe: 2.096 ± 0.382
3.239AsnGly: 3.239 ± 0.629
1.524AsnHis: 1.524 ± 0.704
2.667AsnIle: 2.667 ± 1.454
1.143AsnLys: 1.143 ± 0.863
2.477AsnLeu: 2.477 ± 0.447
0.191AsnMet: 0.191 ± 0.174
0.762AsnAsn: 0.762 ± 0.622
2.096AsnPro: 2.096 ± 0.563
0.953AsnGln: 0.953 ± 0.528
0.953AsnArg: 0.953 ± 0.532
1.905AsnSer: 1.905 ± 0.778
2.858AsnThr: 2.858 ± 0.836
1.524AsnVal: 1.524 ± 0.468
0.0AsnTrp: 0.0 ± 0.0
2.858AsnTyr: 2.858 ± 0.834
0.0AsnXaa: 0.0 ± 0.0
Pro
5.906ProAla: 5.906 ± 1.836
1.143ProCys: 1.143 ± 0.452
3.048ProAsp: 3.048 ± 0.671
3.048ProGlu: 3.048 ± 0.831
2.286ProPhe: 2.286 ± 0.452
3.81ProGly: 3.81 ± 1.19
2.477ProHis: 2.477 ± 0.773
1.905ProIle: 1.905 ± 0.656
3.239ProLys: 3.239 ± 1.01
4.763ProLeu: 4.763 ± 0.591
0.572ProMet: 0.572 ± 0.289
2.286ProAsn: 2.286 ± 0.439
6.096ProPro: 6.096 ± 1.74
1.715ProGln: 1.715 ± 0.562
3.429ProArg: 3.429 ± 0.598
4.763ProSer: 4.763 ± 1.2
5.715ProThr: 5.715 ± 1.037
5.715ProVal: 5.715 ± 1.47
1.143ProTrp: 1.143 ± 0.638
3.048ProTyr: 3.048 ± 0.779
0.0ProXaa: 0.0 ± 0.0
Gln
2.477GlnAla: 2.477 ± 0.992
0.953GlnCys: 0.953 ± 0.403
0.762GlnAsp: 0.762 ± 0.307
1.715GlnGlu: 1.715 ± 0.461
1.143GlnPhe: 1.143 ± 0.342
2.667GlnGly: 2.667 ± 0.501
0.572GlnHis: 0.572 ± 0.364
0.953GlnIle: 0.953 ± 0.347
0.762GlnLys: 0.762 ± 0.331
3.429GlnLeu: 3.429 ± 1.072
0.191GlnMet: 0.191 ± 0.174
1.524GlnAsn: 1.524 ± 0.812
1.334GlnPro: 1.334 ± 0.54
1.524GlnGln: 1.524 ± 0.536
0.762GlnArg: 0.762 ± 0.596
2.286GlnSer: 2.286 ± 0.953
2.096GlnThr: 2.096 ± 0.851
2.477GlnVal: 2.477 ± 0.549
0.191GlnTrp: 0.191 ± 0.258
1.715GlnTyr: 1.715 ± 0.361
0.0GlnXaa: 0.0 ± 0.0
Arg
4.191ArgAla: 4.191 ± 0.67
1.143ArgCys: 1.143 ± 0.601
1.905ArgAsp: 1.905 ± 0.737
1.143ArgGlu: 1.143 ± 0.586
2.286ArgPhe: 2.286 ± 0.677
2.858ArgGly: 2.858 ± 0.522
1.715ArgHis: 1.715 ± 0.692
1.334ArgIle: 1.334 ± 0.675
1.143ArgLys: 1.143 ± 0.495
4.953ArgLeu: 4.953 ± 1.007
0.762ArgMet: 0.762 ± 0.381
2.096ArgAsn: 2.096 ± 0.573
4.382ArgPro: 4.382 ± 0.917
2.096ArgGln: 2.096 ± 0.699
4.001ArgArg: 4.001 ± 0.953
1.905ArgSer: 1.905 ± 0.545
2.858ArgThr: 2.858 ± 0.574
2.858ArgVal: 2.858 ± 0.811
0.381ArgTrp: 0.381 ± 0.432
2.667ArgTyr: 2.667 ± 0.701
0.0ArgXaa: 0.0 ± 0.0
Ser
6.668SerAla: 6.668 ± 0.789
2.286SerCys: 2.286 ± 0.869
2.858SerAsp: 2.858 ± 0.632
2.286SerGlu: 2.286 ± 0.772
3.239SerPhe: 3.239 ± 1.408
4.191SerGly: 4.191 ± 0.832
1.905SerHis: 1.905 ± 1.469
2.477SerIle: 2.477 ± 0.934
2.858SerLys: 2.858 ± 0.836
6.858SerLeu: 6.858 ± 3.11
0.762SerMet: 0.762 ± 0.4
3.048SerAsn: 3.048 ± 1.111
4.572SerPro: 4.572 ± 1.209
1.715SerGln: 1.715 ± 0.604
3.048SerArg: 3.048 ± 0.918
5.525SerSer: 5.525 ± 2.181
4.953SerThr: 4.953 ± 1.518
5.144SerVal: 5.144 ± 1.474
0.762SerTrp: 0.762 ± 0.294
2.667SerTyr: 2.667 ± 0.812
0.0SerXaa: 0.0 ± 0.0
Thr
7.43ThrAla: 7.43 ± 1.449
2.096ThrCys: 2.096 ± 0.528
1.143ThrAsp: 1.143 ± 0.442
2.667ThrGlu: 2.667 ± 0.669
1.715ThrPhe: 1.715 ± 0.642
5.906ThrGly: 5.906 ± 1.803
3.62ThrHis: 3.62 ± 0.731
2.667ThrIle: 2.667 ± 1.047
3.62ThrLys: 3.62 ± 0.635
7.62ThrLeu: 7.62 ± 2.117
0.953ThrMet: 0.953 ± 0.335
2.667ThrAsn: 2.667 ± 0.92
6.668ThrPro: 6.668 ± 1.134
1.143ThrGln: 1.143 ± 0.347
4.382ThrArg: 4.382 ± 1.481
5.334ThrSer: 5.334 ± 1.59
6.477ThrThr: 6.477 ± 1.154
4.001ThrVal: 4.001 ± 0.991
0.953ThrTrp: 0.953 ± 0.701
2.667ThrTyr: 2.667 ± 0.612
0.0ThrXaa: 0.0 ± 0.0
Val
5.525ValAla: 5.525 ± 1.027
2.667ValCys: 2.667 ± 0.94
4.572ValAsp: 4.572 ± 1.383
2.286ValGlu: 2.286 ± 0.792
3.048ValPhe: 3.048 ± 1.229
5.144ValGly: 5.144 ± 0.952
2.286ValHis: 2.286 ± 0.522
3.62ValIle: 3.62 ± 1.052
2.858ValLys: 2.858 ± 0.647
8.383ValLeu: 8.383 ± 0.903
0.953ValMet: 0.953 ± 0.338
2.477ValAsn: 2.477 ± 0.589
4.191ValPro: 4.191 ± 1.517
1.334ValGln: 1.334 ± 0.486
2.096ValArg: 2.096 ± 0.597
5.144ValSer: 5.144 ± 1.369
5.334ValThr: 5.334 ± 1.261
6.477ValVal: 6.477 ± 1.508
0.381ValTrp: 0.381 ± 0.146
2.858ValTyr: 2.858 ± 1.433
0.0ValXaa: 0.0 ± 0.0
Trp
0.762TrpAla: 0.762 ± 0.413
0.191TrpCys: 0.191 ± 0.133
0.762TrpAsp: 0.762 ± 0.39
0.191TrpGlu: 0.191 ± 0.317
1.143TrpPhe: 1.143 ± 0.679
0.572TrpGly: 0.572 ± 0.292
0.0TrpHis: 0.0 ± 0.0
0.381TrpIle: 0.381 ± 0.265
0.572TrpLys: 0.572 ± 0.588
2.286TrpLeu: 2.286 ± 1.021
0.191TrpMet: 0.191 ± 0.23
0.572TrpAsn: 0.572 ± 0.398
0.572TrpPro: 0.572 ± 0.373
0.762TrpGln: 0.762 ± 0.292
0.381TrpArg: 0.381 ± 0.277
0.191TrpSer: 0.191 ± 0.174
0.381TrpThr: 0.381 ± 0.229
0.762TrpVal: 0.762 ± 0.33
0.0TrpTrp: 0.0 ± 0.0
0.762TrpTyr: 0.762 ± 0.511
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.858TyrAla: 2.858 ± 0.802
1.334TyrCys: 1.334 ± 0.563
1.143TyrAsp: 1.143 ± 0.309
0.953TyrGlu: 0.953 ± 0.336
1.334TyrPhe: 1.334 ± 0.395
2.667TyrGly: 2.667 ± 1.023
1.334TyrHis: 1.334 ± 0.804
2.286TyrIle: 2.286 ± 0.495
1.715TyrLys: 1.715 ± 0.628
4.191TyrLeu: 4.191 ± 1.018
0.953TyrMet: 0.953 ± 0.368
1.143TyrAsn: 1.143 ± 0.306
1.334TyrPro: 1.334 ± 0.354
1.143TyrGln: 1.143 ± 0.541
1.143TyrArg: 1.143 ± 0.439
2.096TyrSer: 2.096 ± 0.904
3.62TyrThr: 3.62 ± 1.039
3.239TyrVal: 3.239 ± 0.848
0.381TyrTrp: 0.381 ± 0.146
2.096TyrTyr: 2.096 ± 0.993
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (5250 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski