Amino acid dipepetide frequency for Trichoderma gamsii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.121AlaAla: 10.121 ± 0.068	1.098AlaCys: 1.098 ± 0.018	4.447AlaAsp: 4.447 ± 0.029	5.205AlaGlu: 5.205 ± 0.044	3.198AlaPhe: 3.198 ± 0.022	5.736AlaGly: 5.736 ± 0.04	1.791AlaHis: 1.791 ± 0.019	4.702AlaIle: 4.702 ± 0.032	4.34AlaLys: 4.34 ± 0.038	7.846AlaLeu: 7.846 ± 0.041	2.055AlaMet: 2.055 ± 0.02	3.182AlaAsn: 3.182 ± 0.026	4.71AlaPro: 4.71 ± 0.039	3.526AlaGln: 3.526 ± 0.031	4.742AlaArg: 4.742 ± 0.033	7.727AlaSer: 7.727 ± 0.046	5.468AlaThr: 5.468 ± 0.035	5.509AlaVal: 5.509 ± 0.034	1.2AlaTrp: 1.2 ± 0.02	2.243AlaTyr: 2.243 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	0.927CysAla: 0.927 ± 0.015	0.26CysCys: 0.26 ± 0.008	0.684CysAsp: 0.684 ± 0.012	0.588CysGlu: 0.588 ± 0.01	0.573CysPhe: 0.573 ± 0.011	0.929CysGly: 0.929 ± 0.018	0.336CysHis: 0.336 ± 0.009	0.736CysIle: 0.736 ± 0.012	0.509CysLys: 0.509 ± 0.01	1.243CysLeu: 1.243 ± 0.016	0.254CysMet: 0.254 ± 0.007	0.439CysAsn: 0.439 ± 0.011	0.628CysPro: 0.628 ± 0.012	0.476CysGln: 0.476 ± 0.009	0.72CysArg: 0.72 ± 0.012	0.953CysSer: 0.953 ± 0.016	0.664CysThr: 0.664 ± 0.011	0.774CysVal: 0.774 ± 0.017	0.207CysTrp: 0.207 ± 0.007	0.362CysTyr: 0.362 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	5.001AspAla: 5.001 ± 0.035	0.654AspCys: 0.654 ± 0.012	4.43AspAsp: 4.43 ± 0.041	4.648AspGlu: 4.648 ± 0.041	2.277AspPhe: 2.277 ± 0.023	4.237AspGly: 4.237 ± 0.031	1.197AspHis: 1.197 ± 0.016	3.304AspIle: 3.304 ± 0.027	2.596AspLys: 2.596 ± 0.025	4.965AspLeu: 4.965 ± 0.033	1.328AspMet: 1.328 ± 0.015	1.978AspAsn: 1.978 ± 0.019	3.06AspPro: 3.06 ± 0.026	1.869AspGln: 1.869 ± 0.02	2.898AspArg: 2.898 ± 0.036	4.217AspSer: 4.217 ± 0.034	2.849AspThr: 2.849 ± 0.025	3.728AspVal: 3.728 ± 0.026	0.887AspTrp: 0.887 ± 0.012	1.616AspTyr: 1.616 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.739GluAla: 5.739 ± 0.042	0.612GluCys: 0.612 ± 0.011	4.254GluAsp: 4.254 ± 0.041	5.468GluGlu: 5.468 ± 0.066	1.977GluPhe: 1.977 ± 0.019	3.477GluGly: 3.477 ± 0.032	1.363GluHis: 1.363 ± 0.018	3.134GluIle: 3.134 ± 0.024	3.663GluLys: 3.663 ± 0.038	5.283GluLeu: 5.283 ± 0.042	1.494GluMet: 1.494 ± 0.017	2.29GluAsn: 2.29 ± 0.022	2.73GluPro: 2.73 ± 0.029	2.507GluGln: 2.507 ± 0.028	3.705GluArg: 3.705 ± 0.038	4.326GluSer: 4.326 ± 0.032	3.425GluThr: 3.425 ± 0.028	3.33GluVal: 3.33 ± 0.03	0.899GluTrp: 0.899 ± 0.013	1.653GluTyr: 1.653 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	3.102PheAla: 3.102 ± 0.026	0.553PheCys: 0.553 ± 0.011	2.342PheAsp: 2.342 ± 0.022	2.143PheGlu: 2.143 ± 0.019	1.656PhePhe: 1.656 ± 0.023	2.877PheGly: 2.877 ± 0.029	0.904PheHis: 0.904 ± 0.014	2.014PheIle: 2.014 ± 0.023	1.591PheLys: 1.591 ± 0.019	3.43PheLeu: 3.43 ± 0.033	0.81PheMet: 0.81 ± 0.014	1.511PheAsn: 1.511 ± 0.02	1.914PhePro: 1.914 ± 0.019	1.468PheGln: 1.468 ± 0.016	1.897PheArg: 1.897 ± 0.019	3.124PheSer: 3.124 ± 0.026	2.175PheThr: 2.175 ± 0.021	2.372PheVal: 2.372 ± 0.022	0.642PheTrp: 0.642 ± 0.012	1.128PheTyr: 1.128 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.394GlyAla: 5.394 ± 0.039	0.851GlyCys: 0.851 ± 0.015	3.67GlyAsp: 3.67 ± 0.029	3.618GlyGlu: 3.618 ± 0.028	2.801GlyPhe: 2.801 ± 0.026	5.611GlyGly: 5.611 ± 0.06	1.715GlyHis: 1.715 ± 0.02	3.637GlyIle: 3.637 ± 0.033	3.423GlyLys: 3.423 ± 0.027	6.046GlyLeu: 6.046 ± 0.039	1.492GlyMet: 1.492 ± 0.018	2.648GlyAsn: 2.648 ± 0.025	3.177GlyPro: 3.177 ± 0.029	2.537GlyGln: 2.537 ± 0.025	3.973GlyArg: 3.973 ± 0.026	5.821GlySer: 5.821 ± 0.042	3.799GlyThr: 3.799 ± 0.037	4.217GlyVal: 4.217 ± 0.032	1.152GlyTrp: 1.152 ± 0.015	2.119GlyTyr: 2.119 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.775HisAla: 1.775 ± 0.018	0.323HisCys: 0.323 ± 0.01	1.332HisAsp: 1.332 ± 0.015	1.298HisGlu: 1.298 ± 0.016	0.938HisPhe: 0.938 ± 0.012	1.678HisGly: 1.678 ± 0.018	0.867HisHis: 0.867 ± 0.018	1.26HisIle: 1.26 ± 0.015	0.946HisLys: 0.946 ± 0.012	2.242HisLeu: 2.242 ± 0.023	0.512HisMet: 0.512 ± 0.01	0.874HisAsn: 0.874 ± 0.014	1.532HisPro: 1.532 ± 0.019	1.046HisGln: 1.046 ± 0.017	1.475HisArg: 1.475 ± 0.017	1.814HisSer: 1.814 ± 0.022	1.184HisThr: 1.184 ± 0.016	1.458HisVal: 1.458 ± 0.018	0.343HisTrp: 0.343 ± 0.008	0.688HisTyr: 0.688 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.447IleAla: 4.447 ± 0.033	0.776IleCys: 0.776 ± 0.015	3.051IleAsp: 3.051 ± 0.025	3.037IleGlu: 3.037 ± 0.027	2.112IlePhe: 2.112 ± 0.023	3.362IleGly: 3.362 ± 0.031	1.279IleHis: 1.279 ± 0.017	2.756IleIle: 2.756 ± 0.029	2.395IleLys: 2.395 ± 0.023	4.647IleLeu: 4.647 ± 0.036	1.077IleMet: 1.077 ± 0.014	1.987IleAsn: 1.987 ± 0.021	3.02IlePro: 3.02 ± 0.026	2.099IleGln: 2.099 ± 0.025	2.896IleArg: 2.896 ± 0.024	4.15IleSer: 4.15 ± 0.029	2.93IleThr: 2.93 ± 0.025	3.217IleVal: 3.217 ± 0.03	0.774IleTrp: 0.774 ± 0.013	1.457IleTyr: 1.457 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.53LysAla: 4.53 ± 0.034	0.494LysCys: 0.494 ± 0.012	2.924LysAsp: 2.924 ± 0.024	3.384LysGlu: 3.384 ± 0.032	1.543LysPhe: 1.543 ± 0.018	2.944LysGly: 2.944 ± 0.026	1.12LysHis: 1.12 ± 0.016	2.377LysIle: 2.377 ± 0.024	3.399LysLys: 3.399 ± 0.042	4.305LysLeu: 4.305 ± 0.035	1.061LysMet: 1.061 ± 0.014	1.794LysAsn: 1.794 ± 0.02	2.702LysPro: 2.702 ± 0.027	1.904LysGln: 1.904 ± 0.023	3.334LysArg: 3.334 ± 0.031	3.613LysSer: 3.613 ± 0.031	2.869LysThr: 2.869 ± 0.026	2.77LysVal: 2.77 ± 0.024	0.691LysTrp: 0.691 ± 0.011	1.394LysTyr: 1.394 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	7.997LeuAla: 7.997 ± 0.044	1.219LeuCys: 1.219 ± 0.016	5.308LeuAsp: 5.308 ± 0.035	5.512LeuGlu: 5.512 ± 0.045	3.397LeuPhe: 3.397 ± 0.03	5.939LeuGly: 5.939 ± 0.04	2.173LeuHis: 2.173 ± 0.02	4.101LeuIle: 4.101 ± 0.033	4.303LeuLys: 4.303 ± 0.033	8.486LeuLeu: 8.486 ± 0.056	1.805LeuMet: 1.805 ± 0.018	3.218LeuAsn: 3.218 ± 0.031	5.396LeuPro: 5.396 ± 0.036	3.96LeuGln: 3.96 ± 0.039	5.521LeuArg: 5.521 ± 0.04	7.468LeuSer: 7.468 ± 0.047	4.692LeuThr: 4.692 ± 0.03	5.357LeuVal: 5.357 ± 0.037	1.242LeuTrp: 1.242 ± 0.019	2.376LeuTyr: 2.376 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.379MetAla: 2.379 ± 0.024	0.231MetCys: 0.231 ± 0.007	1.279MetAsp: 1.279 ± 0.017	1.312MetGlu: 1.312 ± 0.017	0.716MetPhe: 0.716 ± 0.011	1.449MetGly: 1.449 ± 0.019	0.455MetHis: 0.455 ± 0.009	1.021MetIle: 1.021 ± 0.014	1.038MetLys: 1.038 ± 0.014	1.925MetLeu: 1.925 ± 0.02	0.604MetMet: 0.604 ± 0.011	0.838MetAsn: 0.838 ± 0.012	1.336MetPro: 1.336 ± 0.02	0.874MetGln: 0.874 ± 0.014	1.273MetArg: 1.273 ± 0.017	1.871MetSer: 1.871 ± 0.02	1.272MetThr: 1.272 ± 0.015	1.256MetVal: 1.256 ± 0.016	0.269MetTrp: 0.269 ± 0.007	0.515MetTyr: 0.515 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.236AsnAla: 3.236 ± 0.023	0.456AsnCys: 0.456 ± 0.01	2.037AsnAsp: 2.037 ± 0.019	2.075AsnGlu: 2.075 ± 0.02	1.434AsnPhe: 1.434 ± 0.018	3.095AsnGly: 3.095 ± 0.037	0.891AsnHis: 0.891 ± 0.012	2.175AsnIle: 2.175 ± 0.021	1.687AsnLys: 1.687 ± 0.019	3.292AsnLeu: 3.292 ± 0.025	0.91AsnMet: 0.91 ± 0.016	1.653AsnAsn: 1.653 ± 0.023	2.355AsnPro: 2.355 ± 0.023	1.396AsnGln: 1.396 ± 0.016	1.973AsnArg: 1.973 ± 0.018	2.942AsnSer: 2.942 ± 0.031	2.15AsnThr: 2.15 ± 0.024	2.331AsnVal: 2.331 ± 0.024	0.586AsnTrp: 0.586 ± 0.013	1.111AsnTyr: 1.111 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.066ProAla: 5.066 ± 0.042	0.52ProCys: 0.52 ± 0.012	3.086ProAsp: 3.086 ± 0.026	3.657ProGlu: 3.657 ± 0.031	2.066ProPhe: 2.066 ± 0.022	3.74ProGly: 3.74 ± 0.037	1.268ProHis: 1.268 ± 0.016	2.603ProIle: 2.603 ± 0.025	2.651ProLys: 2.651 ± 0.027	4.748ProLeu: 4.748 ± 0.034	1.102ProMet: 1.102 ± 0.016	2.207ProAsn: 2.207 ± 0.022	4.906ProPro: 4.906 ± 0.069	2.42ProGln: 2.42 ± 0.031	3.21ProArg: 3.21 ± 0.029	5.762ProSer: 5.762 ± 0.041	3.67ProThr: 3.67 ± 0.032	3.375ProVal: 3.375 ± 0.027	0.739ProTrp: 0.739 ± 0.011	1.467ProTyr: 1.467 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.601GlnAla: 3.601 ± 0.03	0.449GlnCys: 0.449 ± 0.009	2.12GlnAsp: 2.12 ± 0.024	2.365GlnGlu: 2.365 ± 0.025	1.372GlnPhe: 1.372 ± 0.018	2.463GlnGly: 2.463 ± 0.025	1.075GlnHis: 1.075 ± 0.016	1.951GlnIle: 1.951 ± 0.019	1.995GlnLys: 1.995 ± 0.02	3.658GlnLeu: 3.658 ± 0.031	0.917GlnMet: 0.917 ± 0.015	1.588GlnAsn: 1.588 ± 0.021	2.566GlnPro: 2.566 ± 0.027	2.575GlnGln: 2.575 ± 0.046	2.62GlnArg: 2.62 ± 0.027	3.131GlnSer: 3.131 ± 0.026	2.292GlnThr: 2.292 ± 0.023	2.179GlnVal: 2.179 ± 0.02	0.605GlnTrp: 0.605 ± 0.01	1.18GlnTyr: 1.18 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.548ArgAla: 4.548 ± 0.031	0.7ArgCys: 0.7 ± 0.014	3.348ArgAsp: 3.348 ± 0.034	3.629ArgGlu: 3.629 ± 0.037	2.083ArgPhe: 2.083 ± 0.019	3.609ArgGly: 3.609 ± 0.033	1.552ArgHis: 1.552 ± 0.018	2.946ArgIle: 2.946 ± 0.028	3.233ArgLys: 3.233 ± 0.028	5.435ArgLeu: 5.435 ± 0.041	1.243ArgMet: 1.243 ± 0.016	2.205ArgAsn: 2.205 ± 0.02	3.386ArgPro: 3.386 ± 0.035	2.599ArgGln: 2.599 ± 0.025	4.851ArgArg: 4.851 ± 0.049	4.624ArgSer: 4.624 ± 0.046	2.998ArgThr: 2.998 ± 0.024	3.173ArgVal: 3.173 ± 0.026	0.884ArgTrp: 0.884 ± 0.014	1.632ArgTyr: 1.632 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.893SerAla: 6.893 ± 0.039	0.907SerCys: 0.907 ± 0.014	4.297SerAsp: 4.297 ± 0.032	4.192SerGlu: 4.192 ± 0.034	3.127SerPhe: 3.127 ± 0.025	5.63SerGly: 5.63 ± 0.037	1.987SerHis: 1.987 ± 0.02	4.245SerIle: 4.245 ± 0.033	3.883SerLys: 3.883 ± 0.031	7.388SerLeu: 7.388 ± 0.043	1.757SerMet: 1.757 ± 0.019	3.164SerAsn: 3.164 ± 0.03	5.299SerPro: 5.299 ± 0.054	3.406SerGln: 3.406 ± 0.029	4.953SerArg: 4.953 ± 0.041	9.036SerSer: 9.036 ± 0.072	5.345SerThr: 5.345 ± 0.044	4.573SerVal: 4.573 ± 0.033	1.184SerTrp: 1.184 ± 0.015	2.123SerTyr: 2.123 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.35ThrAla: 5.35 ± 0.038	0.731ThrCys: 0.731 ± 0.014	2.814ThrAsp: 2.814 ± 0.022	3.071ThrGlu: 3.071 ± 0.031	2.217ThrPhe: 2.217 ± 0.022	4.043ThrGly: 4.043 ± 0.037	1.185ThrHis: 1.185 ± 0.016	3.171ThrIle: 3.171 ± 0.029	2.636ThrLys: 2.636 ± 0.024	5.093ThrLeu: 5.093 ± 0.034	1.21ThrMet: 1.21 ± 0.014	2.137ThrAsn: 2.137 ± 0.022	4.017ThrPro: 4.017 ± 0.036	2.03ThrGln: 2.03 ± 0.021	2.933ThrArg: 2.933 ± 0.024	5.087ThrSer: 5.087 ± 0.041	4.041ThrThr: 4.041 ± 0.042	3.627ThrVal: 3.627 ± 0.03	0.833ThrTrp: 0.833 ± 0.013	1.568ThrTyr: 1.568 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.371ValAla: 5.371 ± 0.036	0.808ValCys: 0.808 ± 0.013	3.69ValAsp: 3.69 ± 0.024	3.702ValGlu: 3.702 ± 0.03	2.423ValPhe: 2.423 ± 0.026	3.826ValGly: 3.826 ± 0.036	1.311ValHis: 1.311 ± 0.015	3.083ValIle: 3.083 ± 0.024	2.888ValLys: 2.888 ± 0.025	5.45ValLeu: 5.45 ± 0.038	1.288ValMet: 1.288 ± 0.015	2.244ValAsn: 2.244 ± 0.022	3.448ValPro: 3.448 ± 0.027	2.329ValGln: 2.329 ± 0.019	3.195ValArg: 3.195 ± 0.027	4.591ValSer: 4.591 ± 0.037	3.474ValThr: 3.474 ± 0.027	4.164ValVal: 4.164 ± 0.036	0.864ValTrp: 0.864 ± 0.014	1.697ValTyr: 1.697 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.198TrpAla: 1.198 ± 0.018	0.195TrpCys: 0.195 ± 0.006	0.946TrpAsp: 0.946 ± 0.015	0.839TrpGlu: 0.839 ± 0.013	0.548TrpPhe: 0.548 ± 0.01	0.924TrpGly: 0.924 ± 0.012	0.364TrpHis: 0.364 ± 0.008	0.806TrpIle: 0.806 ± 0.013	0.812TrpLys: 0.812 ± 0.013	1.385TrpLeu: 1.385 ± 0.018	0.363TrpMet: 0.363 ± 0.007	0.674TrpAsn: 0.674 ± 0.013	0.641TrpPro: 0.641 ± 0.012	0.578TrpGln: 0.578 ± 0.009	0.936TrpArg: 0.936 ± 0.015	1.053TrpSer: 1.053 ± 0.015	0.913TrpThr: 0.913 ± 0.013	0.86TrpVal: 0.86 ± 0.014	0.288TrpTrp: 0.288 ± 0.008	0.417TrpTyr: 0.417 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.171TyrAla: 2.171 ± 0.021	0.425TyrCys: 0.425 ± 0.009	1.681TyrAsp: 1.681 ± 0.019	1.583TyrGlu: 1.583 ± 0.02	1.196TyrPhe: 1.196 ± 0.014	2.132TyrGly: 2.132 ± 0.023	0.754TyrHis: 0.754 ± 0.012	1.448TyrIle: 1.448 ± 0.017	1.166TyrLys: 1.166 ± 0.016	2.604TyrLeu: 2.604 ± 0.024	0.631TyrMet: 0.631 ± 0.011	1.153TyrAsn: 1.153 ± 0.016	1.438TyrPro: 1.438 ± 0.018	1.101TyrGln: 1.101 ± 0.016	1.575TyrArg: 1.575 ± 0.016	2.077TyrSer: 2.077 ± 0.02	1.585TyrThr: 1.585 ± 0.019	1.577TyrVal: 1.577 ± 0.017	0.448TyrTrp: 0.448 ± 0.01	0.931TyrTyr: 0.931 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11178 proteins (5506319 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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