Amino acid dipepetide frequency for Chlamydia psittaci 84-8471/1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.88AlaAla: 4.88 ± 0.162
1.085AlaCys: 1.085 ± 0.071
2.773AlaAsp: 2.773 ± 0.102
3.648AlaGlu: 3.648 ± 0.124
3.217AlaPhe: 3.217 ± 0.115
3.529AlaGly: 3.529 ± 0.118
1.358AlaHis: 1.358 ± 0.072
4.978AlaIle: 4.978 ± 0.141
4.215AlaLys: 4.215 ± 0.12
8.237AlaLeu: 8.237 ± 0.205
1.673AlaMet: 1.673 ± 0.082
2.549AlaAsn: 2.549 ± 0.094
2.479AlaPro: 2.479 ± 0.092
2.514AlaGln: 2.514 ± 0.096
2.773AlaArg: 2.773 ± 0.108
5.311AlaSer: 5.311 ± 0.133
3.371AlaThr: 3.371 ± 0.116
4.166AlaVal: 4.166 ± 0.134
0.595AlaTrp: 0.595 ± 0.049
2.458AlaTyr: 2.458 ± 0.091
0.0AlaXaa: 0.0 ± 0.0
Cys
0.903CysAla: 0.903 ± 0.066
0.525CysCys: 0.525 ± 0.056
0.697CysAsp: 0.697 ± 0.048
0.837CysGlu: 0.837 ± 0.054
1.078CysPhe: 1.078 ± 0.061
1.12CysGly: 1.12 ± 0.071
0.403CysHis: 0.403 ± 0.037
1.138CysIle: 1.138 ± 0.06
0.77CysLys: 0.77 ± 0.046
2.139CysLeu: 2.139 ± 0.09
0.413CysMet: 0.413 ± 0.042
0.616CysAsn: 0.616 ± 0.046
0.809CysPro: 0.809 ± 0.059
0.592CysGln: 0.592 ± 0.048
0.83CysArg: 0.83 ± 0.063
1.736CysSer: 1.736 ± 0.078
0.669CysThr: 0.669 ± 0.047
1.015CysVal: 1.015 ± 0.061
0.2CysTrp: 0.2 ± 0.026
0.658CysTyr: 0.658 ± 0.05
0.0CysXaa: 0.0 ± 0.0
Asp
3.046AspAla: 3.046 ± 0.104
0.662AspCys: 0.662 ± 0.051
1.803AspAsp: 1.803 ± 0.093
2.601AspGlu: 2.601 ± 0.105
2.535AspPhe: 2.535 ± 0.102
2.184AspGly: 2.184 ± 0.099
1.064AspHis: 1.064 ± 0.064
3.522AspIle: 3.522 ± 0.108
2.909AspLys: 2.909 ± 0.095
5.146AspLeu: 5.146 ± 0.123
1.085AspMet: 1.085 ± 0.063
1.918AspAsn: 1.918 ± 0.07
2.223AspPro: 2.223 ± 0.093
1.498AspGln: 1.498 ± 0.08
2.093AspArg: 2.093 ± 0.084
3.179AspSer: 3.179 ± 0.102
2.356AspThr: 2.356 ± 0.088
2.948AspVal: 2.948 ± 0.11
0.406AspTrp: 0.406 ± 0.038
1.782AspTyr: 1.782 ± 0.072
0.0AspXaa: 0.0 ± 0.0
Glu
4.554GluAla: 4.554 ± 0.137
0.777GluCys: 0.777 ± 0.056
3.319GluAsp: 3.319 ± 0.103
5.584GluGlu: 5.584 ± 0.185
2.402GluPhe: 2.402 ± 0.09
3.735GluGly: 3.735 ± 0.113
1.614GluHis: 1.614 ± 0.08
4.694GluIle: 4.694 ± 0.137
4.957GluLys: 4.957 ± 0.128
5.549GluLeu: 5.549 ± 0.152
1.463GluMet: 1.463 ± 0.072
3.539GluAsn: 3.539 ± 0.112
1.498GluPro: 1.498 ± 0.07
2.345GluGln: 2.345 ± 0.089
3.049GluArg: 3.049 ± 0.119
4.152GluSer: 4.152 ± 0.108
3.144GluThr: 3.144 ± 0.113
3.809GluVal: 3.809 ± 0.129
0.487GluTrp: 0.487 ± 0.042
1.719GluTyr: 1.719 ± 0.073
0.0GluXaa: 0.0 ± 0.0
Phe
2.951PheAla: 2.951 ± 0.101
1.19PheCys: 1.19 ± 0.061
2.013PheAsp: 2.013 ± 0.08
1.929PheGlu: 1.929 ± 0.082
3.214PhePhe: 3.214 ± 0.149
2.871PheGly: 2.871 ± 0.098
1.099PheHis: 1.099 ± 0.063
3.287PheIle: 3.287 ± 0.099
2.272PheLys: 2.272 ± 0.09
6.693PheLeu: 6.693 ± 0.182
0.966PheMet: 0.966 ± 0.055
1.747PheAsn: 1.747 ± 0.088
2.671PhePro: 2.671 ± 0.096
1.467PheGln: 1.467 ± 0.08
2.016PheArg: 2.016 ± 0.08
6.109PheSer: 6.109 ± 0.177
2.282PheThr: 2.282 ± 0.079
2.559PheVal: 2.559 ± 0.101
0.553PheTrp: 0.553 ± 0.045
1.911PheTyr: 1.911 ± 0.089
0.0PheXaa: 0.0 ± 0.0
Gly
3.791GlyAla: 3.791 ± 0.128
1.194GlyCys: 1.194 ± 0.068
2.741GlyAsp: 2.741 ± 0.101
3.501GlyGlu: 3.501 ± 0.108
3.007GlyPhe: 3.007 ± 0.115
4.148GlyGly: 4.148 ± 0.155
1.089GlyHis: 1.089 ± 0.069
4.94GlyIle: 4.94 ± 0.147
4.512GlyLys: 4.512 ± 0.135
5.685GlyLeu: 5.685 ± 0.154
1.642GlyMet: 1.642 ± 0.075
2.559GlyAsn: 2.559 ± 0.101
1.575GlyPro: 1.575 ± 0.069
1.673GlyGln: 1.673 ± 0.07
2.444GlyArg: 2.444 ± 0.093
4.509GlySer: 4.509 ± 0.14
2.927GlyThr: 2.927 ± 0.104
4.103GlyVal: 4.103 ± 0.124
0.616GlyTrp: 0.616 ± 0.05
2.156GlyTyr: 2.156 ± 0.082
0.0GlyXaa: 0.0 ± 0.0
His
1.68HisAla: 1.68 ± 0.074
0.396HisCys: 0.396 ± 0.039
0.956HisAsp: 0.956 ± 0.059
1.162HisGlu: 1.162 ± 0.062
1.19HisPhe: 1.19 ± 0.073
1.278HisGly: 1.278 ± 0.064
0.777HisHis: 0.777 ± 0.063
1.862HisIle: 1.862 ± 0.092
1.446HisLys: 1.446 ± 0.069
2.836HisLeu: 2.836 ± 0.113
0.438HisMet: 0.438 ± 0.04
1.145HisAsn: 1.145 ± 0.067
1.46HisPro: 1.46 ± 0.079
1.106HisGln: 1.106 ± 0.058
1.264HisArg: 1.264 ± 0.074
1.827HisSer: 1.827 ± 0.073
1.358HisThr: 1.358 ± 0.071
1.684HisVal: 1.684 ± 0.076
0.21HisTrp: 0.21 ± 0.025
0.931HisTyr: 0.931 ± 0.058
0.0HisXaa: 0.0 ± 0.0
Ile
5.23IleAla: 5.23 ± 0.139
1.176IleCys: 1.176 ± 0.073
3.672IleAsp: 3.672 ± 0.107
4.435IleGlu: 4.435 ± 0.125
4.033IlePhe: 4.033 ± 0.125
3.886IleGly: 3.886 ± 0.124
1.953IleHis: 1.953 ± 0.088
4.53IleIle: 4.53 ± 0.124
3.732IleLys: 3.732 ± 0.12
8.083IleLeu: 8.083 ± 0.184
1.288IleMet: 1.288 ± 0.062
2.58IleAsn: 2.58 ± 0.094
3.819IlePro: 3.819 ± 0.132
2.717IleGln: 2.717 ± 0.09
3.298IleArg: 3.298 ± 0.103
5.986IleSer: 5.986 ± 0.148
4.106IleThr: 4.106 ± 0.108
4.267IleVal: 4.267 ± 0.138
0.536IleTrp: 0.536 ± 0.042
2.31IleTyr: 2.31 ± 0.092
0.0IleXaa: 0.0 ± 0.0
Lys
4.103LysAla: 4.103 ± 0.128
0.609LysCys: 0.609 ± 0.046
3.462LysAsp: 3.462 ± 0.125
5.433LysGlu: 5.433 ± 0.15
2.055LysPhe: 2.055 ± 0.086
3.077LysGly: 3.077 ± 0.112
1.677LysHis: 1.677 ± 0.075
5.181LysIle: 5.181 ± 0.158
5.248LysLys: 5.248 ± 0.142
5.496LysLeu: 5.496 ± 0.12
1.533LysMet: 1.533 ± 0.069
3.515LysAsn: 3.515 ± 0.107
1.985LysPro: 1.985 ± 0.087
2.871LysGln: 2.871 ± 0.096
3.056LysArg: 3.056 ± 0.106
4.362LysSer: 4.362 ± 0.127
4.015LysThr: 4.015 ± 0.136
3.574LysVal: 3.574 ± 0.113
0.487LysTrp: 0.487 ± 0.043
1.743LysTyr: 1.743 ± 0.072
0.0LysXaa: 0.0 ± 0.0
Leu
7.635LeuAla: 7.635 ± 0.188
1.89LeuCys: 1.89 ± 0.087
4.765LeuAsp: 4.765 ± 0.111
6.55LeuGlu: 6.55 ± 0.139
5.829LeuPhe: 5.829 ± 0.163
7.306LeuGly: 7.306 ± 0.138
2.622LeuHis: 2.622 ± 0.091
6.97LeuIle: 6.97 ± 0.151
6.427LeuLys: 6.427 ± 0.161
11.854LeuLeu: 11.854 ± 0.248
2.447LeuMet: 2.447 ± 0.092
4.246LeuAsn: 4.246 ± 0.126
5.423LeuPro: 5.423 ± 0.155
4.659LeuGln: 4.659 ± 0.139
5.094LeuArg: 5.094 ± 0.138
10.527LeuSer: 10.527 ± 0.189
5.538LeuThr: 5.538 ± 0.146
6.021LeuVal: 6.021 ± 0.14
1.127LeuTrp: 1.127 ± 0.069
3.308LeuTyr: 3.308 ± 0.106
0.0LeuXaa: 0.0 ± 0.0
Met
1.463MetAla: 1.463 ± 0.067
0.301MetCys: 0.301 ± 0.033
1.117MetAsp: 1.117 ± 0.069
1.372MetGlu: 1.372 ± 0.069
0.966MetPhe: 0.966 ± 0.063
1.372MetGly: 1.372 ± 0.072
0.721MetHis: 0.721 ± 0.056
1.673MetIle: 1.673 ± 0.063
1.621MetLys: 1.621 ± 0.073
2.409MetLeu: 2.409 ± 0.102
0.508MetMet: 0.508 ± 0.048
0.98MetAsn: 0.98 ± 0.058
0.914MetPro: 0.914 ± 0.061
0.928MetGln: 0.928 ± 0.057
1.25MetArg: 1.25 ± 0.065
1.603MetSer: 1.603 ± 0.075
1.344MetThr: 1.344 ± 0.063
1.25MetVal: 1.25 ± 0.066
0.151MetTrp: 0.151 ± 0.024
0.564MetTyr: 0.564 ± 0.046
0.0MetXaa: 0.0 ± 0.0
Asn
2.433AsnAla: 2.433 ± 0.083
0.669AsnCys: 0.669 ± 0.046
1.565AsnAsp: 1.565 ± 0.074
2.069AsnGlu: 2.069 ± 0.081
2.191AsnPhe: 2.191 ± 0.098
1.897AsnGly: 1.897 ± 0.085
1.365AsnHis: 1.365 ± 0.077
3.126AsnIle: 3.126 ± 0.116
2.895AsnLys: 2.895 ± 0.103
4.533AsnLeu: 4.533 ± 0.137
0.854AsnMet: 0.854 ± 0.055
1.978AsnAsn: 1.978 ± 0.09
2.706AsnPro: 2.706 ± 0.103
1.75AsnGln: 1.75 ± 0.086
1.932AsnArg: 1.932 ± 0.097
3.018AsnSer: 3.018 ± 0.097
2.381AsnThr: 2.381 ± 0.086
2.454AsnVal: 2.454 ± 0.084
0.27AsnTrp: 0.27 ± 0.033
1.425AsnTyr: 1.425 ± 0.065
0.0AsnXaa: 0.0 ± 0.0
Pro
2.356ProAla: 2.356 ± 0.096
0.721ProCys: 0.721 ± 0.059
1.894ProAsp: 1.894 ± 0.075
3.571ProGlu: 3.571 ± 0.106
2.191ProPhe: 2.191 ± 0.087
2.57ProGly: 2.57 ± 0.094
1.372ProHis: 1.372 ± 0.075
3.13ProIle: 3.13 ± 0.104
3.074ProLys: 3.074 ± 0.103
4.628ProLeu: 4.628 ± 0.134
1.001ProMet: 1.001 ± 0.057
1.806ProAsn: 1.806 ± 0.08
1.981ProPro: 1.981 ± 0.11
1.925ProGln: 1.925 ± 0.088
1.659ProArg: 1.659 ± 0.072
3.368ProSer: 3.368 ± 0.11
2.223ProThr: 2.223 ± 0.08
2.482ProVal: 2.482 ± 0.093
0.553ProTrp: 0.553 ± 0.044
1.456ProTyr: 1.456 ± 0.072
0.0ProXaa: 0.0 ± 0.0
Gln
2.941GlnAla: 2.941 ± 0.098
0.434GlnCys: 0.434 ± 0.04
2.051GlnAsp: 2.051 ± 0.084
3.399GlnGlu: 3.399 ± 0.111
1.316GlnPhe: 1.316 ± 0.066
2.755GlnGly: 2.755 ± 0.099
1.05GlnHis: 1.05 ± 0.064
2.391GlnIle: 2.391 ± 0.097
2.878GlnLys: 2.878 ± 0.101
3.728GlnLeu: 3.728 ± 0.116
0.896GlnMet: 0.896 ± 0.054
1.743GlnAsn: 1.743 ± 0.083
1.39GlnPro: 1.39 ± 0.075
1.96GlnGln: 1.96 ± 0.095
1.936GlnArg: 1.936 ± 0.077
2.416GlnSer: 2.416 ± 0.093
1.845GlnThr: 1.845 ± 0.082
2.132GlnVal: 2.132 ± 0.091
0.375GlnTrp: 0.375 ± 0.037
1.054GlnTyr: 1.054 ± 0.061
0.0GlnXaa: 0.0 ± 0.0
Arg
2.738ArgAla: 2.738 ± 0.104
0.886ArgCys: 0.886 ± 0.056
2.237ArgAsp: 2.237 ± 0.086
3.291ArgGlu: 3.291 ± 0.104
2.142ArgPhe: 2.142 ± 0.097
2.503ArgGly: 2.503 ± 0.102
1.124ArgHis: 1.124 ± 0.064
3.494ArgIle: 3.494 ± 0.124
3.48ArgLys: 3.48 ± 0.123
4.786ArgLeu: 4.786 ± 0.135
1.215ArgMet: 1.215 ± 0.062
2.167ArgAsn: 2.167 ± 0.093
1.477ArgPro: 1.477 ± 0.066
1.757ArgGln: 1.757 ± 0.078
2.493ArgArg: 2.493 ± 0.111
3.525ArgSer: 3.525 ± 0.113
1.82ArgThr: 1.82 ± 0.078
3.095ArgVal: 3.095 ± 0.112
0.504ArgTrp: 0.504 ± 0.045
1.782ArgTyr: 1.782 ± 0.088
0.0ArgXaa: 0.0 ± 0.0
Ser
4.961SerAla: 4.961 ± 0.136
1.806SerCys: 1.806 ± 0.073
3.06SerAsp: 3.06 ± 0.103
4.624SerGlu: 4.624 ± 0.12
3.994SerPhe: 3.994 ± 0.127
5.412SerGly: 5.412 ± 0.156
1.936SerHis: 1.936 ± 0.083
5.542SerIle: 5.542 ± 0.145
4.617SerLys: 4.617 ± 0.129
10.355SerLeu: 10.355 ± 0.231
1.792SerMet: 1.792 ± 0.084
2.594SerAsn: 2.594 ± 0.109
4.064SerPro: 4.064 ± 0.124
3.343SerGln: 3.343 ± 0.113
3.935SerArg: 3.935 ± 0.124
8.286SerSer: 8.286 ± 0.207
3.949SerThr: 3.949 ± 0.119
4.887SerVal: 4.887 ± 0.135
0.952SerTrp: 0.952 ± 0.065
2.657SerTyr: 2.657 ± 0.098
0.0SerXaa: 0.0 ± 0.0
Thr
3.609ThrAla: 3.609 ± 0.117
0.872ThrCys: 0.872 ± 0.052
1.936ThrAsp: 1.936 ± 0.08
2.78ThrGlu: 2.78 ± 0.104
2.762ThrPhe: 2.762 ± 0.1
3.06ThrGly: 3.06 ± 0.102
1.348ThrHis: 1.348 ± 0.064
3.739ThrIle: 3.739 ± 0.099
2.762ThrLys: 2.762 ± 0.093
6.34ThrLeu: 6.34 ± 0.15
1.078ThrMet: 1.078 ± 0.059
1.869ThrAsn: 1.869 ± 0.092
2.92ThrPro: 2.92 ± 0.107
1.894ThrGln: 1.894 ± 0.11
2.181ThrArg: 2.181 ± 0.087
4.11ThrSer: 4.11 ± 0.141
3.483ThrThr: 3.483 ± 0.131
3.196ThrVal: 3.196 ± 0.114
0.494ThrTrp: 0.494 ± 0.042
1.523ThrTyr: 1.523 ± 0.081
0.0ThrXaa: 0.0 ± 0.0
Val
3.924ValAla: 3.924 ± 0.139
1.201ValCys: 1.201 ± 0.062
2.888ValAsp: 2.888 ± 0.104
3.301ValGlu: 3.301 ± 0.127
3.462ValPhe: 3.462 ± 0.121
3.452ValGly: 3.452 ± 0.112
1.26ValHis: 1.26 ± 0.081
4.765ValIle: 4.765 ± 0.137
3.238ValLys: 3.238 ± 0.112
6.861ValLeu: 6.861 ± 0.161
1.421ValMet: 1.421 ± 0.068
2.251ValAsn: 2.251 ± 0.097
2.531ValPro: 2.531 ± 0.103
1.862ValGln: 1.862 ± 0.094
2.902ValArg: 2.902 ± 0.105
5.507ValSer: 5.507 ± 0.142
3.018ValThr: 3.018 ± 0.107
4.446ValVal: 4.446 ± 0.146
0.585ValTrp: 0.585 ± 0.044
1.775ValTyr: 1.775 ± 0.074
0.0ValXaa: 0.0 ± 0.0
Trp
0.448TrpAla: 0.448 ± 0.039
0.14TrpCys: 0.14 ± 0.021
0.417TrpAsp: 0.417 ± 0.041
0.7TrpGlu: 0.7 ± 0.055
0.403TrpPhe: 0.403 ± 0.039
0.746TrpGly: 0.746 ± 0.057
0.224TrpHis: 0.224 ± 0.027
0.672TrpIle: 0.672 ± 0.047
0.756TrpLys: 0.756 ± 0.051
1.12TrpLeu: 1.12 ± 0.063
0.256TrpMet: 0.256 ± 0.026
0.438TrpAsn: 0.438 ± 0.04
0.273TrpPro: 0.273 ± 0.032
0.382TrpGln: 0.382 ± 0.04
0.49TrpArg: 0.49 ± 0.04
0.662TrpSer: 0.662 ± 0.055
0.371TrpThr: 0.371 ± 0.036
0.672TrpVal: 0.672 ± 0.044
0.14TrpTrp: 0.14 ± 0.023
0.217TrpTyr: 0.217 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.16TyrAla: 2.16 ± 0.079
0.613TyrCys: 0.613 ± 0.047
1.596TyrAsp: 1.596 ± 0.072
1.603TyrGlu: 1.603 ± 0.079
1.813TyrPhe: 1.813 ± 0.07
1.911TyrGly: 1.911 ± 0.085
0.949TyrHis: 0.949 ± 0.059
2.006TyrIle: 2.006 ± 0.072
1.673TyrLys: 1.673 ± 0.084
3.76TyrLeu: 3.76 ± 0.115
0.539TyrMet: 0.539 ± 0.038
1.271TyrAsn: 1.271 ± 0.066
1.761TyrPro: 1.761 ± 0.082
1.446TyrGln: 1.446 ± 0.066
1.82TyrArg: 1.82 ± 0.082
2.577TyrSer: 2.577 ± 0.106
1.754TyrThr: 1.754 ± 0.086
1.89TyrVal: 1.89 ± 0.083
0.287TyrTrp: 0.287 ± 0.03
1.204TyrTyr: 1.204 ± 0.077
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2863 proteins (285655 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski