Amino acid dipepetide frequency for Bean leafroll virus (BLRV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.148AlaAla: 2.148 ± 0.37
0.859AlaCys: 0.859 ± 0.45
2.577AlaAsp: 2.577 ± 1.207
5.155AlaGlu: 5.155 ± 1.534
3.866AlaPhe: 3.866 ± 1.362
2.148AlaGly: 2.148 ± 0.556
3.007AlaHis: 3.007 ± 1.473
2.577AlaIle: 2.577 ± 0.999
5.155AlaLys: 5.155 ± 1.35
4.725AlaLeu: 4.725 ± 1.789
1.718AlaMet: 1.718 ± 0.901
1.289AlaAsn: 1.289 ± 1.069
3.436AlaPro: 3.436 ± 0.865
0.859AlaGln: 0.859 ± 0.295
7.302AlaArg: 7.302 ± 1.441
5.155AlaSer: 5.155 ± 0.92
4.296AlaThr: 4.296 ± 0.413
4.725AlaVal: 4.725 ± 1.395
1.289AlaTrp: 1.289 ± 0.792
3.866AlaTyr: 3.866 ± 2.231
0.0AlaXaa: 0.0 ± 0.0
Cys
1.718CysAla: 1.718 ± 0.901
0.859CysCys: 0.859 ± 0.45
0.43CysAsp: 0.43 ± 0.356
2.148CysGlu: 2.148 ± 1.037
0.43CysPhe: 0.43 ± 0.323
0.859CysGly: 0.859 ± 0.647
0.859CysHis: 0.859 ± 0.45
0.0CysIle: 0.0 ± 0.0
1.718CysLys: 1.718 ± 0.584
1.289CysLeu: 1.289 ± 0.622
0.0CysMet: 0.0 ± 0.0
0.43CysAsn: 0.43 ± 0.323
2.148CysPro: 2.148 ± 1.176
0.43CysGln: 0.43 ± 0.323
0.0CysArg: 0.0 ± 0.0
0.859CysSer: 0.859 ± 0.647
0.0CysThr: 0.0 ± 0.0
0.43CysVal: 0.43 ± 0.323
0.0CysTrp: 0.0 ± 0.0
1.718CysTyr: 1.718 ± 0.901
0.0CysXaa: 0.0 ± 0.0
Asp
6.014AspAla: 6.014 ± 0.701
1.289AspCys: 1.289 ± 0.622
4.296AspAsp: 4.296 ± 1.989
3.007AspGlu: 3.007 ± 0.74
1.718AspPhe: 1.718 ± 0.901
3.866AspGly: 3.866 ± 0.929
1.289AspHis: 1.289 ± 0.309
2.577AspIle: 2.577 ± 0.491
3.007AspLys: 3.007 ± 1.295
4.725AspLeu: 4.725 ± 0.961
0.859AspMet: 0.859 ± 0.647
2.577AspAsn: 2.577 ± 1.207
2.577AspPro: 2.577 ± 1.207
1.718AspGln: 1.718 ± 0.721
1.718AspArg: 1.718 ± 1.327
4.296AspSer: 4.296 ± 0.815
0.859AspThr: 0.859 ± 0.553
3.007AspVal: 3.007 ± 0.957
0.0AspTrp: 0.0 ± 0.0
2.577AspTyr: 2.577 ± 0.767
0.0AspXaa: 0.0 ± 0.0
Glu
5.155GluAla: 5.155 ± 0.752
2.577GluCys: 2.577 ± 0.739
4.296GluAsp: 4.296 ± 0.6
7.732GluGlu: 7.732 ± 2.849
1.718GluPhe: 1.718 ± 0.584
2.148GluGly: 2.148 ± 0.879
1.718GluHis: 1.718 ± 0.367
4.296GluIle: 4.296 ± 1.989
4.725GluLys: 4.725 ± 1.487
8.162GluLeu: 8.162 ± 1.902
0.859GluMet: 0.859 ± 0.45
1.289GluAsn: 1.289 ± 0.506
3.436GluPro: 3.436 ± 0.734
1.289GluGln: 1.289 ± 0.622
4.725GluArg: 4.725 ± 1.143
5.155GluSer: 5.155 ± 0.777
2.148GluThr: 2.148 ± 1.871
6.014GluVal: 6.014 ± 1.776
0.859GluTrp: 0.859 ± 0.295
2.577GluTyr: 2.577 ± 0.322
0.0GluXaa: 0.0 ± 0.0
Phe
1.289PheAla: 1.289 ± 0.792
2.148PheCys: 2.148 ± 1.037
3.007PheAsp: 3.007 ± 0.957
3.007PheGlu: 3.007 ± 0.957
0.43PhePhe: 0.43 ± 0.356
3.436PheGly: 3.436 ± 0.397
0.859PheHis: 0.859 ± 0.295
2.577PheIle: 2.577 ± 0.618
2.577PheLys: 2.577 ± 1.94
2.148PheLeu: 2.148 ± 0.763
0.859PheMet: 0.859 ± 0.637
2.577PheAsn: 2.577 ± 0.767
0.43PhePro: 0.43 ± 0.356
0.0PheGln: 0.0 ± 0.0
4.296PheArg: 4.296 ± 0.639
4.725PheSer: 4.725 ± 1.422
1.289PheThr: 1.289 ± 0.745
3.436PheVal: 3.436 ± 0.889
0.0PheTrp: 0.0 ± 0.0
0.43PheTyr: 0.43 ± 0.323
0.0PheXaa: 0.0 ± 0.0
Gly
3.436GlyAla: 3.436 ± 1.203
0.859GlyCys: 0.859 ± 0.647
2.148GlyAsp: 2.148 ± 0.515
4.296GlyGlu: 4.296 ± 1.371
3.007GlyPhe: 3.007 ± 0.678
1.289GlyGly: 1.289 ± 0.792
1.289GlyHis: 1.289 ± 0.569
1.718GlyIle: 1.718 ± 0.472
4.296GlyLys: 4.296 ± 0.413
2.577GlyLeu: 2.577 ± 1.421
0.859GlyMet: 0.859 ± 0.295
3.866GlyAsn: 3.866 ± 1.456
2.577GlyPro: 2.577 ± 1.764
1.289GlyGln: 1.289 ± 0.406
4.296GlyArg: 4.296 ± 1.006
3.436GlySer: 3.436 ± 2.104
1.718GlyThr: 1.718 ± 0.745
3.007GlyVal: 3.007 ± 1.295
0.0GlyTrp: 0.0 ± 0.0
2.577GlyTyr: 2.577 ± 1.137
0.0GlyXaa: 0.0 ± 0.0
His
1.289HisAla: 1.289 ± 0.622
0.0HisCys: 0.0 ± 0.0
0.859HisAsp: 0.859 ± 0.553
2.148HisGlu: 2.148 ± 1.319
0.859HisPhe: 0.859 ± 0.45
1.289HisGly: 1.289 ± 0.699
0.0HisHis: 0.0 ± 0.0
1.289HisIle: 1.289 ± 0.309
0.0HisLys: 0.0 ± 0.0
2.148HisLeu: 2.148 ± 1.425
0.859HisMet: 0.859 ± 0.295
2.148HisAsn: 2.148 ± 1.176
0.43HisPro: 0.43 ± 0.356
0.43HisGln: 0.43 ± 0.356
1.718HisArg: 1.718 ± 0.883
2.577HisSer: 2.577 ± 1.244
0.0HisThr: 0.0 ± 0.0
2.148HisVal: 2.148 ± 0.619
0.859HisTrp: 0.859 ± 0.45
2.148HisTyr: 2.148 ± 0.685
0.0HisXaa: 0.0 ± 0.0
Ile
4.296IleAla: 4.296 ± 1.757
0.859IleCys: 0.859 ± 0.647
3.436IleAsp: 3.436 ± 1.206
5.155IleGlu: 5.155 ± 1.253
0.43IlePhe: 0.43 ± 0.356
1.289IleGly: 1.289 ± 0.622
0.859IleHis: 0.859 ± 0.45
1.289IleIle: 1.289 ± 0.745
3.007IleLys: 3.007 ± 0.631
3.866IleLeu: 3.866 ± 1.018
0.43IleMet: 0.43 ± 0.323
5.584IleAsn: 5.584 ± 0.562
4.296IlePro: 4.296 ± 2.073
0.859IleGln: 0.859 ± 0.553
3.436IleArg: 3.436 ± 0.963
3.436IleSer: 3.436 ± 1.411
5.155IleThr: 5.155 ± 2.355
2.577IleVal: 2.577 ± 0.491
0.0IleTrp: 0.0 ± 0.0
0.43IleTyr: 0.43 ± 0.323
0.0IleXaa: 0.0 ± 0.0
Lys
5.155LysAla: 5.155 ± 0.643
0.43LysCys: 0.43 ± 0.356
5.155LysAsp: 5.155 ± 0.767
3.436LysGlu: 3.436 ± 0.907
6.014LysPhe: 6.014 ± 0.946
1.718LysGly: 1.718 ± 0.584
2.148LysHis: 2.148 ± 0.619
5.155LysIle: 5.155 ± 1.112
6.014LysLys: 6.014 ± 0.739
3.436LysLeu: 3.436 ± 0.9
2.148LysMet: 2.148 ± 0.818
3.436LysAsn: 3.436 ± 0.521
4.296LysPro: 4.296 ± 0.622
1.289LysGln: 1.289 ± 0.97
8.162LysArg: 8.162 ± 1.902
5.155LysSer: 5.155 ± 0.725
2.577LysThr: 2.577 ± 0.491
3.866LysVal: 3.866 ± 0.86
1.289LysTrp: 1.289 ± 0.506
0.43LysTyr: 0.43 ± 0.356
0.43LysXaa: 0.43 ± 0.356
Leu
6.443LeuAla: 6.443 ± 1.26
1.718LeuCys: 1.718 ± 0.883
5.155LeuAsp: 5.155 ± 0.962
4.296LeuGlu: 4.296 ± 1.475
0.859LeuPhe: 0.859 ± 0.295
3.007LeuGly: 3.007 ± 1.322
0.859LeuHis: 0.859 ± 0.295
4.725LeuIle: 4.725 ± 1.531
7.732LeuLys: 7.732 ± 1.669
2.148LeuLeu: 2.148 ± 0.772
0.859LeuMet: 0.859 ± 0.663
1.718LeuAsn: 1.718 ± 0.483
8.591LeuPro: 8.591 ± 1.082
4.725LeuGln: 4.725 ± 0.731
2.148LeuArg: 2.148 ± 1.158
4.725LeuSer: 4.725 ± 1.177
4.296LeuThr: 4.296 ± 1.29
4.296LeuVal: 4.296 ± 1.115
0.859LeuTrp: 0.859 ± 0.45
2.148LeuTyr: 2.148 ± 0.686
0.0LeuXaa: 0.0 ± 0.0
Met
0.859MetAla: 0.859 ± 0.599
0.859MetCys: 0.859 ± 0.647
1.289MetAsp: 1.289 ± 1.223
1.289MetGlu: 1.289 ± 0.745
1.289MetPhe: 1.289 ± 0.309
0.43MetGly: 0.43 ± 0.323
2.148MetHis: 2.148 ± 1.176
0.859MetIle: 0.859 ± 0.45
1.289MetLys: 1.289 ± 0.699
1.718MetLeu: 1.718 ± 0.367
1.718MetMet: 1.718 ± 0.883
0.859MetAsn: 0.859 ± 0.599
0.43MetPro: 0.43 ± 0.356
0.43MetGln: 0.43 ± 0.323
0.859MetArg: 0.859 ± 0.45
1.289MetSer: 1.289 ± 0.745
0.859MetThr: 0.859 ± 0.45
3.007MetVal: 3.007 ± 0.751
0.0MetTrp: 0.0 ± 0.0
1.289MetTyr: 1.289 ± 0.309
0.0MetXaa: 0.0 ± 0.0
Asn
3.866AsnAla: 3.866 ± 0.99
0.859AsnCys: 0.859 ± 0.295
2.148AsnAsp: 2.148 ± 0.801
2.148AsnGlu: 2.148 ± 0.619
1.718AsnPhe: 1.718 ± 0.367
6.014AsnGly: 6.014 ± 1.557
0.43AsnHis: 0.43 ± 0.356
2.148AsnIle: 2.148 ± 0.879
3.436AsnLys: 3.436 ± 0.88
2.148AsnLeu: 2.148 ± 0.402
0.859AsnMet: 0.859 ± 0.45
6.014AsnAsn: 6.014 ± 1.406
2.577AsnPro: 2.577 ± 0.322
0.859AsnGln: 0.859 ± 0.713
2.577AsnArg: 2.577 ± 0.767
3.436AsnSer: 3.436 ± 2.447
3.436AsnThr: 3.436 ± 0.397
3.866AsnVal: 3.866 ± 0.681
0.43AsnTrp: 0.43 ± 0.356
1.289AsnTyr: 1.289 ± 0.506
0.0AsnXaa: 0.0 ± 0.0
Pro
1.718ProAla: 1.718 ± 0.902
0.859ProCys: 0.859 ± 0.45
2.577ProAsp: 2.577 ± 1.139
3.866ProGlu: 3.866 ± 0.622
2.577ProPhe: 2.577 ± 0.767
3.007ProGly: 3.007 ± 1.485
1.289ProHis: 1.289 ± 0.792
1.289ProIle: 1.289 ± 0.309
7.302ProLys: 7.302 ± 1.644
5.155ProLeu: 5.155 ± 0.962
0.43ProMet: 0.43 ± 0.356
2.148ProAsn: 2.148 ± 0.37
7.302ProPro: 7.302 ± 2.387
3.436ProGln: 3.436 ± 1.074
4.296ProArg: 4.296 ± 1.58
6.014ProSer: 6.014 ± 1.571
5.155ProThr: 5.155 ± 0.777
6.014ProVal: 6.014 ± 0.921
0.0ProTrp: 0.0 ± 0.0
0.43ProTyr: 0.43 ± 0.323
0.0ProXaa: 0.0 ± 0.0
Gln
3.007GlnAla: 3.007 ± 0.559
0.859GlnCys: 0.859 ± 0.647
0.859GlnAsp: 0.859 ± 0.647
0.43GlnGlu: 0.43 ± 0.323
1.718GlnPhe: 1.718 ± 0.483
1.718GlnGly: 1.718 ± 0.367
1.289GlnHis: 1.289 ± 0.622
0.43GlnIle: 0.43 ± 0.323
1.718GlnLys: 1.718 ± 0.492
2.148GlnLeu: 2.148 ± 0.515
0.859GlnMet: 0.859 ± 0.608
1.289GlnAsn: 1.289 ± 0.792
1.718GlnPro: 1.718 ± 1.425
0.859GlnGln: 0.859 ± 0.663
2.577GlnArg: 2.577 ± 1.501
3.007GlnSer: 3.007 ± 1.169
2.577GlnThr: 2.577 ± 0.742
3.866GlnVal: 3.866 ± 0.438
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.155ArgAla: 5.155 ± 1.987
0.43ArgCys: 0.43 ± 0.323
2.148ArgAsp: 2.148 ± 0.619
1.718ArgGlu: 1.718 ± 0.679
2.148ArgPhe: 2.148 ± 0.772
3.007ArgGly: 3.007 ± 1.457
0.43ArgHis: 0.43 ± 0.61
3.007ArgIle: 3.007 ± 0.547
4.296ArgLys: 4.296 ± 1.17
6.443ArgLeu: 6.443 ± 1.438
2.577ArgMet: 2.577 ± 0.561
3.436ArgAsn: 3.436 ± 0.865
3.436ArgPro: 3.436 ± 1.239
3.866ArgGln: 3.866 ± 1.568
8.162ArgArg: 8.162 ± 2.103
6.873ArgSer: 6.873 ± 1.509
3.007ArgThr: 3.007 ± 3.036
5.584ArgVal: 5.584 ± 0.877
2.577ArgTrp: 2.577 ± 0.767
4.296ArgTyr: 4.296 ± 0.454
0.0ArgXaa: 0.0 ± 0.0
Ser
2.148SerAla: 2.148 ± 1.076
0.0SerCys: 0.0 ± 0.0
1.289SerAsp: 1.289 ± 0.506
5.584SerGlu: 5.584 ± 1.895
4.296SerPhe: 4.296 ± 1.222
5.584SerGly: 5.584 ± 1.974
0.0SerHis: 0.0 ± 0.0
7.732SerIle: 7.732 ± 1.662
6.443SerLys: 6.443 ± 0.935
6.873SerLeu: 6.873 ± 2.615
3.007SerMet: 3.007 ± 1.779
2.577SerAsn: 2.577 ± 0.618
5.584SerPro: 5.584 ± 1.383
3.007SerGln: 3.007 ± 0.819
8.591SerArg: 8.591 ± 3.454
9.88SerSer: 9.88 ± 4.201
3.436SerThr: 3.436 ± 1.446
5.584SerVal: 5.584 ± 1.171
0.43SerTrp: 0.43 ± 0.61
2.148SerTyr: 2.148 ± 0.495
0.0SerXaa: 0.0 ± 0.0
Thr
3.866ThrAla: 3.866 ± 0.475
0.0ThrCys: 0.0 ± 0.0
3.007ThrAsp: 3.007 ± 1.485
3.866ThrGlu: 3.866 ± 0.438
1.718ThrPhe: 1.718 ± 0.483
1.718ThrGly: 1.718 ± 0.492
1.289ThrHis: 1.289 ± 0.309
3.007ThrIle: 3.007 ± 0.74
2.148ThrLys: 2.148 ± 0.556
3.866ThrLeu: 3.866 ± 0.533
2.577ThrMet: 2.577 ± 1.076
2.577ThrAsn: 2.577 ± 2.024
4.725ThrPro: 4.725 ± 1.264
2.148ThrGln: 2.148 ± 0.686
1.289ThrArg: 1.289 ± 0.792
6.014ThrSer: 6.014 ± 2.433
4.296ThrThr: 4.296 ± 1.771
1.289ThrVal: 1.289 ± 0.506
0.43ThrTrp: 0.43 ± 0.356
0.859ThrTyr: 0.859 ± 0.295
0.0ThrXaa: 0.0 ± 0.0
Val
6.014ValAla: 6.014 ± 0.718
0.0ValCys: 0.0 ± 0.0
5.584ValAsp: 5.584 ± 0.966
6.014ValGlu: 6.014 ± 1.673
2.577ValPhe: 2.577 ± 0.556
2.577ValGly: 2.577 ± 0.917
1.718ValHis: 1.718 ± 0.472
2.148ValIle: 2.148 ± 1.037
5.155ValLys: 5.155 ± 1.548
6.014ValLeu: 6.014 ± 0.653
0.43ValMet: 0.43 ± 0.323
2.148ValAsn: 2.148 ± 0.685
5.584ValPro: 5.584 ± 1.139
1.718ValGln: 1.718 ± 0.492
4.296ValArg: 4.296 ± 0.639
4.296ValSer: 4.296 ± 1.73
3.007ValThr: 3.007 ± 0.326
6.873ValVal: 6.873 ± 1.012
0.859ValTrp: 0.859 ± 0.713
3.007ValTyr: 3.007 ± 0.597
0.0ValXaa: 0.0 ± 0.0
Trp
0.43TrpAla: 0.43 ± 0.356
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.718TrpGlu: 1.718 ± 0.883
1.289TrpPhe: 1.289 ± 0.622
0.43TrpGly: 0.43 ± 0.323
0.859TrpHis: 0.859 ± 0.553
0.0TrpIle: 0.0 ± 0.0
0.43TrpLys: 0.43 ± 0.356
0.859TrpLeu: 0.859 ± 0.45
0.0TrpMet: 0.0 ± 0.0
0.43TrpAsn: 0.43 ± 0.356
0.859TrpPro: 0.859 ± 0.45
0.43TrpGln: 0.43 ± 0.323
0.43TrpArg: 0.43 ± 0.61
0.859TrpSer: 0.859 ± 0.713
0.859TrpThr: 0.859 ± 0.713
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.43TrpTyr: 0.43 ± 0.356
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.148TyrAla: 2.148 ± 0.685
0.859TyrCys: 0.859 ± 0.45
1.718TyrAsp: 1.718 ± 0.367
3.866TyrGlu: 3.866 ± 0.968
1.289TyrPhe: 1.289 ± 0.97
3.007TyrGly: 3.007 ± 0.95
0.859TyrHis: 0.859 ± 0.553
3.866TyrIle: 3.866 ± 0.929
1.289TyrLys: 1.289 ± 0.97
0.859TyrLeu: 0.859 ± 0.45
0.43TyrMet: 0.43 ± 0.526
3.866TyrAsn: 3.866 ± 0.475
0.43TyrPro: 0.43 ± 0.356
1.289TyrGln: 1.289 ± 0.532
1.718TyrArg: 1.718 ± 0.367
3.007TyrSer: 3.007 ± 1.53
1.718TyrThr: 1.718 ± 0.367
0.0TyrVal: 0.0 ± 0.0
0.43TyrTrp: 0.43 ± 0.323
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.43XaaVal: 0.43 ± 0.356
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2329 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski