Amino acid dipepetide frequency for Cowpea polerovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.293AlaAla: 6.293 ± 0.659
0.994AlaCys: 0.994 ± 0.424
0.662AlaAsp: 0.662 ± 0.571
2.319AlaGlu: 2.319 ± 0.861
2.319AlaPhe: 2.319 ± 0.728
4.969AlaGly: 4.969 ± 0.648
1.325AlaHis: 1.325 ± 0.622
4.637AlaIle: 4.637 ± 1.024
2.981AlaLys: 2.981 ± 0.98
7.95AlaLeu: 7.95 ± 2.334
1.656AlaMet: 1.656 ± 0.353
2.319AlaAsn: 2.319 ± 0.948
5.3AlaPro: 5.3 ± 0.349
2.319AlaGln: 2.319 ± 0.714
4.306AlaArg: 4.306 ± 0.56
6.625AlaSer: 6.625 ± 1.228
2.981AlaThr: 2.981 ± 0.976
4.637AlaVal: 4.637 ± 2.097
2.319AlaTrp: 2.319 ± 0.448
2.981AlaTyr: 2.981 ± 1.332
0.0AlaXaa: 0.0 ± 0.0
Cys
0.662CysAla: 0.662 ± 0.417
0.0CysCys: 0.0 ± 0.0
0.994CysAsp: 0.994 ± 0.543
0.994CysGlu: 0.994 ± 0.263
1.325CysPhe: 1.325 ± 0.634
0.331CysGly: 0.331 ± 0.463
0.0CysHis: 0.0 ± 0.0
0.662CysIle: 0.662 ± 0.311
2.319CysLys: 2.319 ± 0.699
2.319CysLeu: 2.319 ± 0.879
0.331CysMet: 0.331 ± 0.209
0.331CysAsn: 0.331 ± 0.286
0.994CysPro: 0.994 ± 0.486
1.656CysGln: 1.656 ± 0.433
0.662CysArg: 0.662 ± 0.311
0.994CysSer: 0.994 ± 0.52
0.0CysThr: 0.0 ± 0.0
1.987CysVal: 1.987 ± 0.473
0.0CysTrp: 0.0 ± 0.0
0.331CysTyr: 0.331 ± 0.286
0.0CysXaa: 0.0 ± 0.0
Asp
1.987AspAla: 1.987 ± 0.956
1.987AspCys: 1.987 ± 0.735
4.637AspAsp: 4.637 ± 1.14
2.319AspGlu: 2.319 ± 0.459
2.65AspPhe: 2.65 ± 0.95
1.656AspGly: 1.656 ± 0.497
0.331AspHis: 0.331 ± 0.209
2.65AspIle: 2.65 ± 0.944
0.662AspLys: 0.662 ± 0.571
3.975AspLeu: 3.975 ± 1.643
0.331AspMet: 0.331 ± 0.274
1.987AspAsn: 1.987 ± 0.605
2.65AspPro: 2.65 ± 0.527
2.65AspGln: 2.65 ± 0.818
3.975AspArg: 3.975 ± 1.124
2.981AspSer: 2.981 ± 0.54
3.312AspThr: 3.312 ± 1.221
2.319AspVal: 2.319 ± 1.261
1.656AspTrp: 1.656 ± 0.497
1.325AspTyr: 1.325 ± 0.452
0.0AspXaa: 0.0 ± 0.0
Glu
4.306GluAla: 4.306 ± 0.731
0.662GluCys: 0.662 ± 0.571
4.306GluAsp: 4.306 ± 1.775
3.312GluGlu: 3.312 ± 0.837
2.319GluPhe: 2.319 ± 0.852
6.293GluGly: 6.293 ± 1.354
0.662GluHis: 0.662 ± 0.311
2.319GluIle: 2.319 ± 0.474
0.331GluLys: 0.331 ± 0.318
5.962GluLeu: 5.962 ± 1.52
1.656GluMet: 1.656 ± 0.578
1.325GluAsn: 1.325 ± 0.853
2.65GluPro: 2.65 ± 0.69
1.656GluGln: 1.656 ± 0.578
2.981GluArg: 2.981 ± 0.514
3.644GluSer: 3.644 ± 1.008
2.981GluThr: 2.981 ± 0.787
2.65GluVal: 2.65 ± 0.773
2.981GluTrp: 2.981 ± 0.622
1.987GluTyr: 1.987 ± 0.912
0.0GluXaa: 0.0 ± 0.0
Phe
3.312PheAla: 3.312 ± 0.532
0.331PheCys: 0.331 ± 0.209
0.994PheAsp: 0.994 ± 0.424
3.312PheGlu: 3.312 ± 0.574
2.65PhePhe: 2.65 ± 1.245
2.981PheGly: 2.981 ± 1.171
1.325PheHis: 1.325 ± 0.477
3.644PheIle: 3.644 ± 1.003
2.65PheLys: 2.65 ± 0.866
2.981PheLeu: 2.981 ± 1.122
0.0PheMet: 0.0 ± 0.0
1.656PheAsn: 1.656 ± 0.798
0.994PhePro: 0.994 ± 0.424
1.987PheGln: 1.987 ± 0.751
2.65PheArg: 2.65 ± 1.648
2.981PheSer: 2.981 ± 0.866
0.994PheThr: 0.994 ± 0.464
5.962PheVal: 5.962 ± 1.102
0.331PheTrp: 0.331 ± 0.286
1.325PheTyr: 1.325 ± 0.489
0.0PheXaa: 0.0 ± 0.0
Gly
3.644GlyAla: 3.644 ± 0.397
0.994GlyCys: 0.994 ± 0.263
2.981GlyAsp: 2.981 ± 1.272
3.644GlyGlu: 3.644 ± 0.763
4.637GlyPhe: 4.637 ± 1.202
6.293GlyGly: 6.293 ± 2.463
0.331GlyHis: 0.331 ± 0.286
3.644GlyIle: 3.644 ± 0.829
3.975GlyLys: 3.975 ± 1.029
5.962GlyLeu: 5.962 ± 1.311
1.325GlyMet: 1.325 ± 0.542
2.65GlyAsn: 2.65 ± 0.957
2.65GlyPro: 2.65 ± 0.977
2.65GlyGln: 2.65 ± 1.016
6.625GlyArg: 6.625 ± 2.279
8.612GlySer: 8.612 ± 1.829
2.65GlyThr: 2.65 ± 0.435
5.962GlyVal: 5.962 ± 1.107
0.662GlyTrp: 0.662 ± 0.417
2.319GlyTyr: 2.319 ± 0.712
0.0GlyXaa: 0.0 ± 0.0
His
1.987HisAla: 1.987 ± 0.871
1.325HisCys: 1.325 ± 0.398
1.987HisAsp: 1.987 ± 0.362
1.325HisGlu: 1.325 ± 0.398
0.0HisPhe: 0.0 ± 0.0
0.331HisGly: 0.331 ± 0.286
0.0HisHis: 0.0 ± 0.0
0.331HisIle: 0.331 ± 0.209
0.331HisLys: 0.331 ± 0.209
1.987HisLeu: 1.987 ± 0.65
1.325HisMet: 1.325 ± 0.585
0.662HisAsn: 0.662 ± 0.311
2.319HisPro: 2.319 ± 0.76
0.331HisGln: 0.331 ± 0.209
2.319HisArg: 2.319 ± 0.879
2.65HisSer: 2.65 ± 0.891
0.994HisThr: 0.994 ± 0.464
0.662HisVal: 0.662 ± 0.515
0.0HisTrp: 0.0 ± 0.0
0.662HisTyr: 0.662 ± 0.311
0.0HisXaa: 0.0 ± 0.0
Ile
4.306IleAla: 4.306 ± 0.68
0.331IleCys: 0.331 ± 0.463
1.656IleAsp: 1.656 ± 0.841
1.656IleGlu: 1.656 ± 0.33
2.319IlePhe: 2.319 ± 0.931
1.325IleGly: 1.325 ± 0.347
1.656IleHis: 1.656 ± 0.5
1.656IleIle: 1.656 ± 0.714
2.981IleLys: 2.981 ± 0.787
4.969IleLeu: 4.969 ± 0.588
0.662IleMet: 0.662 ± 0.446
2.65IleAsn: 2.65 ± 0.717
4.306IlePro: 4.306 ± 0.781
0.331IleGln: 0.331 ± 0.209
3.644IleArg: 3.644 ± 1.554
5.631IleSer: 5.631 ± 1.759
3.975IleThr: 3.975 ± 1.313
2.319IleVal: 2.319 ± 1.206
0.0IleTrp: 0.0 ± 0.0
0.994IleTyr: 0.994 ± 0.424
0.0IleXaa: 0.0 ± 0.0
Lys
3.975LysAla: 3.975 ± 0.849
0.994LysCys: 0.994 ± 0.486
1.325LysAsp: 1.325 ± 0.946
0.994LysGlu: 0.994 ± 0.441
2.319LysPhe: 2.319 ± 0.87
4.969LysGly: 4.969 ± 0.97
1.325LysHis: 1.325 ± 0.591
2.65LysIle: 2.65 ± 0.737
0.662LysLys: 0.662 ± 0.296
2.319LysLeu: 2.319 ± 0.906
0.994LysMet: 0.994 ± 0.51
2.981LysAsn: 2.981 ± 1.092
5.962LysPro: 5.962 ± 1.819
1.987LysGln: 1.987 ± 0.737
2.65LysArg: 2.65 ± 0.658
2.65LysSer: 2.65 ± 1.404
5.3LysThr: 5.3 ± 1.742
1.987LysVal: 1.987 ± 0.486
0.662LysTrp: 0.662 ± 0.571
1.656LysTyr: 1.656 ± 0.714
0.331LysXaa: 0.331 ± 0.286
Leu
4.306LeuAla: 4.306 ± 1.483
3.312LeuCys: 3.312 ± 1.37
2.319LeuAsp: 2.319 ± 0.527
5.631LeuGlu: 5.631 ± 1.376
3.644LeuPhe: 3.644 ± 0.98
5.631LeuGly: 5.631 ± 1.998
0.994LeuHis: 0.994 ± 1.109
5.962LeuIle: 5.962 ± 1.343
3.312LeuLys: 3.312 ± 0.944
9.937LeuLeu: 9.937 ± 3.288
0.662LeuMet: 0.662 ± 0.311
1.325LeuAsn: 1.325 ± 0.592
5.962LeuPro: 5.962 ± 1.035
4.637LeuGln: 4.637 ± 0.66
4.969LeuArg: 4.969 ± 1.51
6.625LeuSer: 6.625 ± 0.959
6.293LeuThr: 6.293 ± 1.47
5.631LeuVal: 5.631 ± 1.663
1.325LeuTrp: 1.325 ± 0.47
3.644LeuTyr: 3.644 ± 0.652
0.0LeuXaa: 0.0 ± 0.0
Met
1.987MetAla: 1.987 ± 0.579
0.331MetCys: 0.331 ± 0.209
1.656MetAsp: 1.656 ± 0.801
1.987MetGlu: 1.987 ± 0.43
0.331MetPhe: 0.331 ± 0.463
0.331MetGly: 0.331 ± 0.209
0.662MetHis: 0.662 ± 0.311
0.331MetIle: 0.331 ± 0.209
1.325MetLys: 1.325 ± 0.622
1.987MetLeu: 1.987 ± 0.848
0.331MetMet: 0.331 ± 0.286
0.662MetAsn: 0.662 ± 0.523
0.662MetPro: 0.662 ± 0.311
0.331MetGln: 0.331 ± 0.286
0.0MetArg: 0.0 ± 0.0
1.656MetSer: 1.656 ± 0.969
1.656MetThr: 1.656 ± 0.33
2.319MetVal: 2.319 ± 1.728
0.0MetTrp: 0.0 ± 0.0
0.994MetTyr: 0.994 ± 0.263
0.0MetXaa: 0.0 ± 0.0
Asn
2.981AsnAla: 2.981 ± 1.166
0.662AsnCys: 0.662 ± 0.571
2.319AsnAsp: 2.319 ± 0.621
1.325AsnGlu: 1.325 ± 0.627
0.331AsnPhe: 0.331 ± 0.463
5.3AsnGly: 5.3 ± 2.145
0.994AsnHis: 0.994 ± 0.424
0.662AsnIle: 0.662 ± 0.333
3.644AsnLys: 3.644 ± 0.693
3.644AsnLeu: 3.644 ± 1.202
0.662AsnMet: 0.662 ± 0.471
1.325AsnAsn: 1.325 ± 0.592
1.656AsnPro: 1.656 ± 0.635
0.994AsnGln: 0.994 ± 0.263
6.625AsnArg: 6.625 ± 2.102
1.987AsnSer: 1.987 ± 0.883
3.975AsnThr: 3.975 ± 1.148
0.662AsnVal: 0.662 ± 0.446
0.0AsnTrp: 0.0 ± 0.0
2.319AsnTyr: 2.319 ± 1.343
0.0AsnXaa: 0.0 ± 0.0
Pro
4.969ProAla: 4.969 ± 1.455
0.662ProCys: 0.662 ± 0.296
1.987ProAsp: 1.987 ± 0.821
3.975ProGlu: 3.975 ± 0.895
1.325ProPhe: 1.325 ± 0.372
3.975ProGly: 3.975 ± 0.859
1.325ProHis: 1.325 ± 0.55
4.306ProIle: 4.306 ± 1.094
2.65ProLys: 2.65 ± 0.957
2.981ProLeu: 2.981 ± 1.275
1.987ProMet: 1.987 ± 0.453
1.987ProAsn: 1.987 ± 0.986
7.618ProPro: 7.618 ± 2.461
1.656ProGln: 1.656 ± 0.59
5.3ProArg: 5.3 ± 1.578
4.969ProSer: 4.969 ± 1.071
4.306ProThr: 4.306 ± 0.826
2.65ProVal: 2.65 ± 0.569
1.325ProTrp: 1.325 ± 0.622
1.325ProTyr: 1.325 ± 0.601
0.0ProXaa: 0.0 ± 0.0
Gln
3.975GlnAla: 3.975 ± 1.245
0.0GlnCys: 0.0 ± 0.0
1.987GlnAsp: 1.987 ± 0.746
1.325GlnGlu: 1.325 ± 0.591
1.656GlnPhe: 1.656 ± 0.664
1.325GlnGly: 1.325 ± 0.592
1.656GlnHis: 1.656 ± 0.624
0.662GlnIle: 0.662 ± 0.311
2.65GlnLys: 2.65 ± 0.875
3.975GlnLeu: 3.975 ± 0.89
0.331GlnMet: 0.331 ± 0.286
2.65GlnAsn: 2.65 ± 0.717
0.331GlnPro: 0.331 ± 0.286
1.325GlnGln: 1.325 ± 0.611
3.312GlnArg: 3.312 ± 0.963
1.987GlnSer: 1.987 ± 1.248
1.987GlnThr: 1.987 ± 0.605
2.319GlnVal: 2.319 ± 0.714
1.325GlnTrp: 1.325 ± 0.824
1.325GlnTyr: 1.325 ± 0.622
0.0GlnXaa: 0.0 ± 0.0
Arg
4.306ArgAla: 4.306 ± 2.183
0.0ArgCys: 0.0 ± 0.0
2.65ArgAsp: 2.65 ± 1.301
3.312ArgGlu: 3.312 ± 0.785
4.306ArgPhe: 4.306 ± 1.306
5.962ArgGly: 5.962 ± 2.048
2.319ArgHis: 2.319 ± 0.751
3.312ArgIle: 3.312 ± 1.032
3.312ArgLys: 3.312 ± 0.857
4.969ArgLeu: 4.969 ± 1.419
0.662ArgMet: 0.662 ± 0.442
6.293ArgAsn: 6.293 ± 2.961
3.975ArgPro: 3.975 ± 1.1
1.656ArgGln: 1.656 ± 0.779
9.275ArgArg: 9.275 ± 4.298
5.962ArgSer: 5.962 ± 0.992
4.969ArgThr: 4.969 ± 0.724
3.312ArgVal: 3.312 ± 0.904
0.994ArgTrp: 0.994 ± 0.504
2.65ArgTyr: 2.65 ± 0.928
0.0ArgXaa: 0.0 ± 0.0
Ser
2.981SerAla: 2.981 ± 0.97
0.662SerCys: 0.662 ± 0.311
3.644SerAsp: 3.644 ± 0.397
2.65SerGlu: 2.65 ± 1.0
2.319SerPhe: 2.319 ± 0.66
10.931SerGly: 10.931 ± 1.92
2.319SerHis: 2.319 ± 0.966
5.3SerIle: 5.3 ± 1.279
2.981SerLys: 2.981 ± 0.605
7.618SerLeu: 7.618 ± 1.356
1.325SerMet: 1.325 ± 0.398
4.306SerAsn: 4.306 ± 0.964
5.962SerPro: 5.962 ± 2.39
2.65SerGln: 2.65 ± 0.59
5.962SerArg: 5.962 ± 1.926
11.924SerSer: 11.924 ± 2.498
4.969SerThr: 4.969 ± 0.817
4.637SerVal: 4.637 ± 0.987
2.319SerTrp: 2.319 ± 0.712
2.65SerTyr: 2.65 ± 1.36
0.0SerXaa: 0.0 ± 0.0
Thr
4.969ThrAla: 4.969 ± 1.003
1.656ThrCys: 1.656 ± 0.5
3.644ThrAsp: 3.644 ± 1.255
3.644ThrGlu: 3.644 ± 0.523
3.644ThrPhe: 3.644 ± 1.142
3.975ThrGly: 3.975 ± 1.181
1.987ThrHis: 1.987 ± 0.579
1.325ThrIle: 1.325 ± 0.398
3.312ThrLys: 3.312 ± 1.556
2.981ThrLeu: 2.981 ± 0.824
2.981ThrMet: 2.981 ± 0.672
1.656ThrAsn: 1.656 ± 0.578
3.975ThrPro: 3.975 ± 0.436
2.65ThrGln: 2.65 ± 0.717
2.319ThrArg: 2.319 ± 0.959
6.956ThrSer: 6.956 ± 1.074
3.644ThrThr: 3.644 ± 0.821
3.975ThrVal: 3.975 ± 1.437
0.994ThrTrp: 0.994 ± 0.493
0.662ThrTyr: 0.662 ± 0.311
0.0ThrXaa: 0.0 ± 0.0
Val
3.975ValAla: 3.975 ± 1.195
0.331ValCys: 0.331 ± 0.463
4.306ValAsp: 4.306 ± 1.101
6.625ValGlu: 6.625 ± 0.937
2.65ValPhe: 2.65 ± 0.391
4.306ValGly: 4.306 ± 1.005
0.662ValHis: 0.662 ± 0.311
2.65ValIle: 2.65 ± 0.677
4.969ValLys: 4.969 ± 1.102
5.962ValLeu: 5.962 ± 1.3
1.325ValMet: 1.325 ± 0.654
1.987ValAsn: 1.987 ± 0.585
2.981ValPro: 2.981 ± 1.005
2.319ValGln: 2.319 ± 0.852
2.65ValArg: 2.65 ± 1.356
3.975ValSer: 3.975 ± 1.214
2.65ValThr: 2.65 ± 0.77
3.975ValVal: 3.975 ± 0.862
1.656ValTrp: 1.656 ± 0.5
0.994ValTyr: 0.994 ± 0.711
0.0ValXaa: 0.0 ± 0.0
Trp
0.662TrpAla: 0.662 ± 0.571
0.662TrpCys: 0.662 ± 0.296
1.325TrpAsp: 1.325 ± 0.452
2.65TrpGlu: 2.65 ± 0.736
0.662TrpPhe: 0.662 ± 0.311
0.331TrpGly: 0.331 ± 0.286
0.662TrpHis: 0.662 ± 0.523
0.0TrpIle: 0.0 ± 0.0
0.331TrpLys: 0.331 ± 0.286
1.325TrpLeu: 1.325 ± 0.47
0.331TrpMet: 0.331 ± 0.209
0.994TrpAsn: 0.994 ± 0.263
0.331TrpPro: 0.331 ± 0.209
0.662TrpGln: 0.662 ± 0.311
2.319TrpArg: 2.319 ± 0.79
3.312TrpSer: 3.312 ± 1.292
1.987TrpThr: 1.987 ± 0.486
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.306TyrAla: 4.306 ± 0.827
0.994TyrCys: 0.994 ± 0.424
0.662TyrAsp: 0.662 ± 0.571
1.987TyrGlu: 1.987 ± 0.749
1.656TyrPhe: 1.656 ± 0.592
1.325TyrGly: 1.325 ± 0.494
0.994TyrHis: 0.994 ± 0.631
0.662TyrIle: 0.662 ± 0.436
3.312TyrLys: 3.312 ± 1.346
2.319TyrLeu: 2.319 ± 0.537
0.331TyrMet: 0.331 ± 0.286
2.319TyrAsn: 2.319 ± 0.589
0.0TyrPro: 0.0 ± 0.0
1.656TyrGln: 1.656 ± 0.33
1.656TyrArg: 1.656 ± 0.779
1.987TyrSer: 1.987 ± 0.456
1.325TyrThr: 1.325 ± 0.452
2.65TyrVal: 2.65 ± 0.648
0.0TyrTrp: 0.0 ± 0.0
0.994TyrTyr: 0.994 ± 0.885
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.331XaaVal: 0.331 ± 0.286
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (3020 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski